CIDRAP Antimicrobial Stewardship Project Newsletter – Jan 9, 2020


In this week's issue:

  • What's new at CIDRAP-ASP
  • Diagnostics and data processing in LMICs
  • Antimicrobial stewardship and AMR surveillance in Ghana
  • Responsible antibiotic use in animal agriculture
  • Consensus statement on UTI treatment in post-acute and long-term care
  • Pharmacist-led stewardship in Uganda
  • Industry and policy perspectives on antibiotic development
  • Use of unregistered antibiotics in Australia
  • Regulations for collaborative stewardship in India
  • Partnerships between stewardship and infection control programs
  • Use of the neonatal early-onset sepsis calculator in the Netherlands
  • Surveillance data and infographics on AMR and stewardship in Canada




[Connect] Please join us in congratulating CIDRAP-ASP Advisory Committee member Debra Goff, PharmD, who is one of 25 people selected by the World Health Organization to help healthcare professionals and government leaders implement antimicrobial stewardship plans in low- and middle-income countries. And the January 2020 issue of the Journal of the American Medical Directors Association features numerous articles on antimicrobial resistance (AMR) and stewardship in US long-term care settings, including a study of interventions to reduce fluoroquinolone use and Clostridioides difficile infections in nursing homes by Christina B. Felsen, MPH, and colleagues, including CIDRAP-ASP Advisory Committee member Elizabeth S. Dodds Ashley, PharmD, MHS.


[Weigh In] Test your memory and take our most popular quiz from 2019 to gauge your knowledge of antimicrobial stewardship pledges from a fast food restaurant and a group of stakeholders in animal agriculture.


[Read] CIDRAP News recently published stories on a study of decolonizing parents to reduce the spread of Staphylococcus aureus to newborns, the bankruptcy filing from antibiotic developer Melinta Therapeutics, extensively drug-resistant Shigella in Australia, and much more.


[Research] Please take a moment to visit our recently launched compendium of databases and tools for AMR surveillance, our antimicrobial stewardship diagnostics resources, our database containing hundreds of publicly available clinical tools for antimicrobial stewardship programs, and our educational multimedia page. The surveillance and diagnostics pages are updated at least weekly, and we add new clinical and educational tools monthly.


[Stay Current] If you'd like to stay current on all our news and events, please follow CIDRAP-ASP on Twitter and Facebook, subscribe to our YouTube channel, and subscribe to our antimicrobial stewardship podcasts on iTunes.




[Rethink] France-based bioMérieux announced that it has been selected as a supplier in a tender process by the Fleming Fund to tackle AMR in low- and middle-income countries by equipping one reference clinical laboratory and one veterinary laboratory in 18 countries across Africa and the Asia-Pacific region with diagnostic, susceptibility testing, and data processing technology over the next 3 years.


[Explore] In a feature story for the Ghana News Agency, Prosper Kuorsoh describes the progression of AMR in Ghana, along with perspectives from policymakers and clinicians on antimicrobial stewardship and the development of a regulatory framework for responsible antibiotic use. And on the blog of the UK Animal & Plant Health Agency, Rod Card, PhD, details the surveillance and laboratory capacity work of the AMR Reference Centre in Ghana.


[Learn] The US National Institute for Animal Agriculture published a white paper synthesizing presentations that occurred at its October 2019 symposium on "Communicating the Science of Responsible Antibiotic Use in Animal Agriculture."


[Study] In the Journal of the American Medical Directors Association (AMDA), Muhammad S. Ashraf, MBBS, and other members of the AMDA Infection Advisory Subcommittee provide a consensus statement on the diagnosis, treatment, and prevention of urinary tract infections in post-acute and long-term care.


[Discover] On IDStewardship, Krutika N. Mediwala, PharmD, and Timothy P. Gauthier, PharmD, interview Peter Babigumira Ahabwe, BPharm, and Winnie Nambatya, MPharm, about opportunities and barriers related to antimicrobial stewardship in Uganda and paths to becoming involved in stewardship practice and advocacy.


[Evaluate] On Contagion, Rolf Wagenaar, MS, provides an industry perspective on the problems plaguing antibiotic development, asserting that healthcare professionals should be empowered with data to use new antibiotics for patients who need them without the fear of financial repercussions. And on Stat, Allan Coukell, BScPharm, offers a policy perspective on national economic incentives to spur antibiotic development and reimbursement in the US.


[Analyze] In Infection, Disease & Health, Nadine T. Hillock, BPharm, MPH, et al found that 18,362 applications to access unregistered antimicrobials were submitted to the Australian Therapeutic Goods Administration from 2012 to 2017, with 51.4% indicated by the prescriber to be for life-threatening infections. The authors discuss the need for regulatory pathways to facilitate both antimicrobial access and safety, given the potential increase in need for novel and unregistered drugs.


[Peruse] In The Week, Namita Kohli, MA, speaks with Balram Bhargava, MBBS, MD, about policies and regulations to enact collaborative antimicrobial stewardship in India. And The New Humanitarian lists AMR as 1 of 10 humanitarian crises deserving attention in 2020.


[Assess] In Infection Control Today, Frank Diamond interviews Katherine K. Perez, PharmD, about how antimicrobial stewardship and infection prevention and control programs can collaborate on similar goals while remaining committed to preserving the strengths and unique processes of each separate program.


[Examine] In the European Journal of Pediatrics, Niek B. Achten, MD, et al assess the implementation of the neonatal early-onset sepsis (EOS) calculator in a Dutch hospital, finding that the tool was associated with significant reductions in EOS laboratory tests and antibiotic days. The researchers also note that the calculator was associated with shorter hospital stays and lower financial costs among term, but not preterm, infants.


[Engage] On Stat, David Mateo Ricci describes his personal experiences with an antibiotic-resistant infection and the need to involve patients in antimicrobial stewardship policy and advocacy. And on the blog of the US Office of the Assistant Secretary for Preparedness and Response, Rick Bright, PhD, describes a personal experience with a drug-resistant infection, along with challenges confronting diagnostic and susceptibility testing along the US hospital, primary, and emergency care pathways.


[Review] The January 2020 issue of the Canada Communicable Disease Report focuses on AMR in Canada and includes a review of prescriber-led antimicrobial stewardship changes associated with the national "Using Antibiotics Wisely" campaign, a surveillance study of drug-resistant tuberculosis across the provinces, and three infographics on AMR in Canadian healthcare, community, and agricultural settings.

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