CIDRAP Antimicrobial Stewardship Project Newsletter – Nov 21, 2019


In this week's issue:

  • What's new at CIDRAP-ASP
  • Contest for global AMR symbol
  • Antimicrobial sales for animals in Finland
  • Antibiotic access, substandard drugs, and AMR in Kenya
  • AMR and children living in poverty
  • Stewardship tools for long-term care settings
  • Roadmap for antibiotic durations in US animal agriculture
  • Diagnosis and management of MDR Acinetobacter baumannii
  • Applicability of climate change tactics to stewardship efforts
  • Australian campaigns to balance antibiotic overuse and sepsis response
  • Risk factors for antifungal resistance in healthcare and agriculture
  • US-India AMR surveillance and drug development partnerships
  • Online course on agricultural antibiotic stewardship
  • Antibiotic allergy and risk of MRSA colonization
  • Substandard drugs, typhoid misdiagnosis, and AMR in Nigeria
  • Concrete actions for AMR governance and policy




[Connect] In a Breakpoints podcast miniseries from the Society of Infectious Diseases Pharmacists, CIDRAP-ASP Advisory Committee member Arjun Srinivasan, MD, along with Erin McCreary, PharmD and Melinda Neuhauser, PharmD, MPH, discuss the newly released 2019 US Centers for Disease Control and Prevention (CDC) Core Elements of Hospital Antibiotic Stewardship Programs, while Susan Davis, PharmD, and Jason Pogue, PharmD, describe features of the "5 Ways Hospital Pharmacists Can Be Antibiotics Aware" campaign.


[Weigh In] Take our November quiz to gauge your knowledge on the challenges of developing new antibiotics. And to learn more, read a recent CIDRAP News story on antibiotic development issues and opportunities experienced by pharmaceutical companies and clinicians.


[Read] CIDRAP News recently published stories on updates to the US CDC's core elements of hospital antibiotic stewardship programs, antibiotic knowledge among European health workers, US Food and Drug Administration (FDA) approval of cefiderocol for complicated urinary tract infections, and much more.


[Research] Please take a moment to visit our recently launched compendium of databases and tools for antimicrobial resistance (AMR) surveillance, our antimicrobial stewardship diagnostics resources, our database containing hundreds of publicly available clinical tools for antimicrobial stewardship programs, and our educational multimedia page. The surveillance and diagnostics pages are updated at least weekly, and we add new clinical and educational tools monthly.


[Stay Current] If you'd like to stay current on all our news and events, please follow CIDRAP-ASP on Twitter and Facebook, subscribe to our YouTube channel, and subscribe to our antimicrobial stewardship podcasts on iTunes.




[Apply] The EU Joint Action on Antimicrobial Resistance and Healthcare-Associated Infections invites designs for a symbol that represents the global threat of AMR. Symbols must be something that anyone can make and wear, and designs are due by Mar 31, 2020.


[Discover] The Finnish Food Authority, the Finnish Medicines Agency Fimea, and the University of Helsinki published the FINRES-Vet 2018 report, which showed that antimicrobial sales for food-producing animals decreased by 18% from 2014 to 2018.


[Explore] Devex features an in-depth look at issues contributing to AMR in Kenya, including low pharmacy supplies of first-line antibiotics, the presence of substandard medicines, and the misuse of drugs across the food chain, also highlighting the importance of translating global policy to locally feasible and multisectoral action. And in advance of the 30th anniversary of the adoption of the United Nations Convention on the Rights of the Child, ReAct highlights the effect of AMR on children, particularly those living in poverty.


[Peruse] Choosing Wisely Canada released tools, recommendations, and patient resources for using antibiotics appropriately in long-term care settings. And Mediaplanet's Global Cause platform features a compendium of articles on AMR, antimicrobial and antifungal stewardship, and laboratory testing for World Antibiotic Awareness Week 2019.


[Learn] In an article for the Pew Charitable Trusts, Karin Hoelzer, DVM, PhD, proposes a milestone-driven roadmap with clear goals to be met within a 5-year timeframe, allowing the FDA to establish evidence-based durations of use for medically important antibiotics in animal agriculture.


[Examine] In Current Infectious Disease Reports, David A. Butler, PharmD, et al review the diagnosis and antimicrobial management of multidrug-resistant Acinetobacter baumannii, advocating for the combined use of antimicrobial stewardship and rapid diagnostic testing to avoid potentially toxic combination therapy and shorten time to effective treatment.


[Assess] In The Economist, Charles Clift, PhD, MA, discusses the potential applicability of tactics used to tackle climate change to the management of AMR, asserting that AMR must be viewed as an issue of infrastructure and public health development rather than as a problem that can be solved through a series of technical fixes. And in an article for the University of Melbourne, Karin Thursky, MBBS, MD, and Arjun Rajkhowa, PhD, describe Australian initiatives to recognize and treat sepsis rapidly while protecting against the overuse of antibiotics.


[Listen] On Weill Cornell Medicine's Kids Health Cast podcast, Melanie Cole, MS, interviews Paul Chung, MD, about situations in which children should and shouldn't receive antibiotics.


[Analyze] In Current Infectious Disease Reports, Joshua A. Hendrickson, PharmD, et al provide an overview of risk factors for development of antifungal resistance in Candida and Aspergillus species encountered in clinical and agricultural settings.


[Engage] In The Hindu, C. Maya reports on the launch of an antibiotic awareness campaign in the Indian state of Kerala with the goal that everyone in Kerala becomes "antibiotic literate" by 2020. And in the Hindustan Times, US ambassador to India Kenneth I. Juster, JD, MPP, describes partnerships between the US and Indian governments to address AMR, surveillance, and drug development in both countries, urging the importance of an individual and collective response.


[Study] FAI Farms launched on online course on "Antimicrobial Stewardship in the Food Chain: Tackling the Global Challenge of Antibiotic Resistance," facilitated by Laura Higham, BVM&S, MSc.


[Evaluate] In the American Journal of Infection Control, Weyman Lam, MD, et al found that an antibiotic allergy label was associated with a higher prevalence of colonization with methicillin-resistant Staphylococcus aureus in patients at a US hospital.


[Rethink] On Nigeria Health Watch, Patience Adejo describes situations surrounding the misdiagnosis of typhoid and subsequent overuse of antibiotics in Nigeria, advocating for greater attention to training and guideline compliance related to management of suspected typhoid. And in Vanguard, BPharm candidate Melody Okereke describes issues related to AMR in Nigeria, including self-prescription and the prevalence of substandard antimicrobial agents.


[Review] In The Lancet, Susan Rogers Van Katwyk, PhD, et al describe three concrete actions toward governance, leadership, and policy development that can be taken now to ensure sustainable access to effective antibiotics.

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