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The plan includes a $2.8 billion boost to HHS but cuts to global health.
The budget supports earlier commitment to Gavi vaccine initiatives but dials back funds for other global health efforts.
In other developments, the HHS announced more funding for a rapid Ebola test.
UN funding is needed to cover its response activities in the region through 2015, with an urgent need to ramp up before the rainy season.
The administration today asked Congress for $6.18 billion in emergency funds.
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