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"Fighting Zika is the most complex epidemic response CDC has taken on," Frieden says.
Also, a review of blood samples suggests Zika-linked microcephaly in Hawaii as far back as 2009.
The data show different rates of defects but shed light on the link between exposure timing and poor outcomes.
The report adds to the growing body of literature linking Zika to a rise in microcephaly.
Also, New York's first 80 cases point to the usefulness of urine testing for diagnosis.
Findings from "minibrain" experiments raise new questions on how Zika infects developing fetal brain cells.
Also, a second mouse study finds evidence that the virus damages testes and fertility.
The agency shifts to long-term response, which it says is more likely to provide sustained funding.
A DNA vaccine could help stamp out the outbreak, while a live-attenuated vaccine could offer lifelong immunity.
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