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The new drug is a 'modernized' version of tetracycline, designed to address antibiotic resistance, but its clinical role isn't yet clear.
A total of 62.4% of patients taking tafenoquine were free of P vivax after 6 months.
Brazil has confirmed almost 1,000 human cases since July 2016, and cases in animals have doubled.
Strains in Africa are becoming more drug resistant.
The cost study looked at different attack-rate ranges, putting the upper-end estimate at as much as $2 billion.
Tocantins joins Para, Rio de Janeiro, Sao Paulo, Espirito Santo, and Minas Gerais as states with confirmed human yellow fever cases.
Outbreak responders hope to get a jump on mosquitoes by scaling up vaccination during a dry period.
The disease persists in Angola, local cases were reported in a new part of the DRC's Kinshasa province, and investigators are looking at cases in other nations.
The findings are similar to earlier studies showing Wolbachia's ability to cut dengue transmission.
Also, a study found distinct temporal patterns between cases, GBS, and microcephaly.
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