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Gaps the GAO identified include instances of agencies overseeing their own labs, a need for more focus on the highest-risk activities, and understaffing.
The most common pathogens not properly inactivated were Bacillus anthracis and Francisella tularensis.
High-containment labs across the US government, including the CDC, have safety gaps, the GAO says.
The plan includes ways to improve safety and security at US labs that conduct infectious disease research.
The CDC proposes adding certain H5N1 viruses to HHS's select agent list; experts have varied reactions.
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