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The patients, hospitalized at a speciality center, had a variety of complications and some unusual features.
The Florida study suggests a 'perfect storm' of conditions made Miami a favorable setting for Zika and that mosquito control helped reduce disease levels.
In other Zika news, Florida reported more local Zika cases over the past few days, officials announced the launch of a vaccine trial, and Palau reported its first local case.
It's called antibody-dependent enhancement (ADE), wherein the dengue vaccine sets up severe disease in those not previously exposed — and it might have repercussions for Zika.
The study sheds light on how Zika antibodies bind to the virus. Also, Florida is investigating four possible local cases now, all from the same two counties: Broward and neighboring Miami-Dade.
Also, a study found distinct temporal patterns between cases, GBS, and microcephaly.
Structure details may yield clues on how Zika damages cells and offer an inside track to drug, vaccine, and test developers.
The approach could be used to screen other dengue vaccine candidates, as well as for Zika vaccines.
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CIDRAP - Center for Infectious Disease Research and PolicyOffice of the Vice President for Research, University of Minnesota, Minneapolis, MN
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