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In other developments, a few more cases were reported in the Americas and mosquito trials showed a risk of spread in major Kenyan cities.
The Florida study suggests a 'perfect storm' of conditions made Miami a favorable setting for Zika and that mosquito control helped reduce disease levels.
Also, reseachers identify a Zika antibody that might open up new therapy and vaccine possibilities.
Ecuador reports its first yellow fever case since 2012, and, based on the latest Brazil developments, the WHO updates its travel recommendations.
"Fighting Zika is the most complex epidemic response CDC has taken on," Frieden says.
The data show different rates of defects but shed light on the link between exposure timing and poor outcomes.
The report adds to the growing body of literature linking Zika to a rise in microcephaly.
Elsewhere, Florida notes 9 new local cases, and the WHO spells out its research agenda.
Study today provides more evidence of a strong link between Zika and Guillain-Barre syndrome.
Also, the CDC announced $2.4 million to help large cities detect and manage birth defects, and researchers revealed possible differences in brain cell infections between the 2 Zika lineages.
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