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Although vaccines have saved millions of lives, experts estimate that, since 2016, cases have increased by more than 30%.
Trinidad and Tobago as well as Vietnam report suspected Zika-linked microcephaly.
Other new reports detail co-infections with other mosquito-borne viruses and fatal encephalitis.
In other developments, a transgenic mosquito project is in the works for Grand Cayman and Spain reported a travel-linked microcephaly case.
Study says 2.2 billion people live in areas suitable for Zika spread, and over the next year more than 5 million babies will be born in vulnerable parts of the Americas.
Experts said only 2 of the new methods—Wolbachia and transgenic mosquitoes—were at the stage for carefully designed pilot projects.
CDC guidance now excludes destinations above 6,500 feet, as Aedes mosquitoes are rare in those areas.
Also, Brazil's health ministry rejected a possible microcephaly link to larvicides, and experts are gathering for a US Zika priority workshop tomorrow.
The WHO's top drug and development official projected the launch of a large vaccine trial is still at least 18 months away, but a test might be available within weeks.
Seven outbreak countries are seeing a rise in microcephaly or Guillain-Barre disease.
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