(CIDRAP News) – Researchers from the University of Maryland School of Medicine have reported laboratory evidence of Plasmodium falciparum cross-resistance between trimethoprim-sulfamethoxazole, one of the standard treatments for HIV patients in Africa, and sulfadoxine-pyrimethamine, the first-line antimalarial drug in parts of Africa.
(CIDRAP News) – Macrolide antibiotics, the mainstay of treatment for community-acquired pneumonia, are encountering increasing resistance from Streptococcus pneumoniae, the most common cause of the disease, according to a report in the Oct 17 issue of the Journal of the American Medical Association.
(CIDRAP News) A recent analysis of ground pork in grocery stores in five states showed that 4% of the samples contained enterococci with high-level resistance to gentamicin, an antibiotic used to treat enterococcal infections in humans. In addition, most Enterococcus faecium isolates were resistant to quinupristin-dalfopristin (Synercid), a streptogramin antibiotic used to treat infections caused by vancomycin-resistant E faecium.
(CIDRAP News) A study from Taiwan shows a rapid increase in fluoroquinolone resistance in Salmonella enterica serotype choleraesuis in humans over the past 2 years and suggests that the resistant strain spread from pigs. The findings prompted the researchers to urge a ban on fluoroquinoline use in food animals.
(CIDRAP News) Nearly a year and a half after the Food and Drug Administration (FDA) first proposed to stop the use of enrofloxacin (Baytril, a fluoroquinolone antibiotic) in poultry because of safety concerns, the agency says it plans to hold a public hearing on the proposal. The date of the hearing will be set at a prehearing conference on April 8.
A ruling by the Food and Drug Administration on whether to stop the use of enrofloxacin in poultry because of concern about antimicrobial resistance is more than a year away, according to a hearing schedule laid out by an FDA official.
In a Danish study, patients who had infections with a common drug-resistant type of Salmonella enterica were more than twice as likely to die within 2 years as patients infected with drug-susceptible variants of the same strain.
(CIDRAP News) A committee of experts convened by the Alliance for the Prudent Use of Antibiotics (APUA) says that antibiotics should not be used in agriculture except to treat sick animals and protect healthy animals threatened by disease in the herd or flock.