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Scientists are seeing high rates of treatment failure as they struggle to eliminate the disease in the region.
On World Malaria Day, global health leaders aired concerns about stalled progress in some regions and recommitted to the battle against the disease.
Strains with key drug-resistance genes grew from 16% of samples in 2008 to 68% in 2013.
Recent gains in preventing the disease in pregnancy may be lost as resistance to prophylactic treatment rises.
Researchers identify more than 80 genes that contribute to resistance.
Meta-analysis shows a 21% higher antibiotic prescribing rate in patients who tested negative for malaria.
UK researchers report that a frontline drug combo failed in 4 patients.
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