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The study also found that MRSA infections declined in all facilities, perhaps due to other prevention steps.
Genetic analysis suggested the isolates were unique to the NIH Clinical Center.
The study dashes hopes that combining piperacillin and tazobactam might help prevent overuse of carbapenems.
Researchers say better communication about antibiotics is needed, and dentists need to be included in stewardship programs.
Removing sinks and using a "water-free" method of care reduced colonization with gram-negative bacilli.
Data showed an interesting ebb and flow, as well as evidence of slowly increasing bacterial resistance.
Though the CDC reported good progress earlier this year, central-line infections remain a key problem.
The bacterium may have recently evolved to spread person to person, as it becomes more virulent.
The WHO says preventive antibiotics should be used before and during surgery but not after.
The pockets and sleeves of nurses' scrubs showed contamination 10% of the time.
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