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The country has had 337 new cases this week, twice the number in Guinea and Liberia combined.
Bats in a hollow tree and a silent train of transmission may have fueled the unprecedented epidemic.
Scotland detected its first Ebola case, as the illness toll topped 20,000 and the outbreak passed the 1-year mark.
Sierra Leone's western area is seeing intense Ebola activity, and in Guinea a surge of cases in one area propelled the country into its highest weekly case incidence so far.
The authors say the findings have proved useful in creating a more potent version.
The CDC director said Ebola outbreak conditions have improved since his first visit, but tough challenges remain.
In the first stop of a 3-day tour, the UN director warned against easing up on response efforts.
New information now indicates phase 2 trials will most likely start in Africa in February.
Case counts vary, but progress is being made toward the UN goal of isolating & treating, and safely burying where necessary, all Ebola patients.
A report in MMWR details challenges investigation teams in West Africa have faced.
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