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The preliminary genetic analysis suggest that some of the internal genes have changed, compared to earlier H5N6 samples from China and Hong Kong.
The findings may explain infection in people who don't have direct bird contact.
Cameroon's recent outbreak is its first since 2006 and signals southern movement of the virus, the FAO said.
Pennsylvania, New York, and New Jersey reported outbreaks, which a USDA spokesperson said are not uncommon at live markets.
Cambodia, Ghana, and Indonesia report H5N1, and Italy notes its 2nd H7N7 event this month.
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