News & Perspective

Nov 15, 2007

Nov 15, 2007

THE PANDEMIC VACCINE PUZZLE Can we vaccinate enough people in time to matter?

Maryn McKennaContributing Writer

(CIDRAP News) – This in-depth article investigates the prospects for development of vaccines to head off the threat of an influenza pandemic posed by the H5N1 avian influenza virus. Its seven parts put advances in vaccine technology in perspective by illuminating the formidable barriers to producing an effective and widely usable vaccine in a short time frame.

Nov 02, 2007

Nov 02, 2007

THE PANDEMIC VACCINE PUZZLE Part 7: Time for a vaccine 'Manhattan Project'?

Editor's note: This is the last in a seven-part series investigating the prospects for development of vaccines to head off the threat of an influenza pandemic posed by the H5N1 avian influenza virus. The series puts promising advances in vaccine technology in perspective by illuminating the formidable barriers to producing large amounts of an effective and widely usable vaccine in a short time.

Oct 25, 2007

Oct 25, 2007

THE PANDEMIC VACCINE PUZZLE Bibliography

Editor's note: This is the bibliography to a seven-part series launched October 25, 2007, investigating the prospects for development of vaccines to head off the threat of an influenza pandemic posed by the H5N1 avian influenza virus. The series puts advances in vaccine technology in perspective by illuminating the formidable barriers to producing an effective and widely usable vaccine in a short time frame.

Oct 25, 2007

THE PANDEMIC VACCINE PUZZLE Part 1: Flu research: a legacy of neglect

Editor's note: This is the first in a seven-part series investigating the prospects for development of vaccines to head off the threat of an influenza pandemic posed by the H5N1 avian influenza virus. The series puts advances in vaccine technology in perspective by illuminating the formidable barriers to producing an effective and widely usable vaccine in a short time frame.

Aug 10, 2007

Aug 10, 2007

Researchers create H5N1 mutations to pave way for new vaccines and treatments

(CIDRAP News) – Global health officials have long feared genetic changes that would make the H5N1 avian influenza virus more easily transmissible among humans, but a new report from researchers at the National Institute of Allergy and Infectious Diseases (NIAID) predicts some of the crucial mutations, which could open the door to preemptive vaccines and treatments.

Jul 19, 2007

Jul 19, 2007

HHS updates pandemic stockpile totals and planning efforts

(CIDRAP News) – In an update on the nation's pandemic preparedness efforts, the US Department of Health and Human Services (HHS) yesterday said it had stockpiled enough H5N1 avian influenza vaccine to protect about 6 million people and that federal and state supplies contain enough antiviral medication to treat more than 48 million.

Jul 16, 2007

Jul 16, 2007

Study: Inhibiting cytokine response might not reverse H5N1 infections

(CIDRAP News) – Scientists have hoped that disabling the body's destructive immune-system overreaction to the H5N1 avian influenza virus, known as "cytokine storm," could lead to new lifesaving treatments, but according to a new study, trials testing the strategy didn't protect mice infected with the disease.

Jun 08, 2007

Jun 08, 2007

Human antibodies protect mice from H5N1 avian flu

(CIDRAP News) – Antibodies gleaned from four Vietnamese patients who survived H5N1 avian influenza were used successfully to prevent and treat H5N1 infection in mice, suggesting that the same approach might be useful in humans, according to a recent report by an international team of researchers.

May 29, 2007

May 29, 2007

Welsh officials announce four H7N2 flu cases, suspect human-to-human transmission

(CIDRAP News) - Four people in Wales and northwest England have tested positive for the low-pathogenic H7N2 avian influenza subtype found last week in chickens at a small farm in Wales, and local public health authorities suspect some degree of human-to-human transmission of the disease.

Apr 04, 2007

Apr 04, 2007

NIAID unveils multicenter flu research initiative

(CIDRAP News) – In a major effort to track influenza viruses in nature and learn more about how they interact with the human body, the federal government this week announced a $23-million-a-year program to fund research centers at six institutions around the country.

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