News & Perspective

Oct 19, 2017

Oct 19, 2017
Ferret

Study details pandemic potential of latest H7N9 flu strains

In a sample from a patient who died, researchers saw signs that the H7N9 virus had started to mutate to a form resistant to Tamiflu.

Mar 08, 2016

Mar 08, 2016
Influenza researcher

COMMENTARY: Six policy options for conducting gain-of-function research

Experts offer approaches for moving the GOF conundrum forward that are not mutually exclusive, such as lifting the moratorium, seeking international consensus, and establishing a review board.

Mar 29, 2013

Mar 29, 2013

Scientists seek ethics review of H5N1 gain-of-function research

(CIDRAP News) – A group of scientists acting under the aegis of a vaccine research advocacy organization has asked President Obama's bioethics committee to evaluate the ethics of experiments designed to increase the transmissibility of H5N1 avian influenza viruses.

Jun 21, 2012

Jun 21, 2012

Fouchier study reveals changes enabling airborne spread of H5N1

(CIDRAP News) – A study showing that it takes as few as five mutations to turn the H5N1 avian influenza virus into an airborne spreader in mammals—and that launched a historic debate on scientific accountability and transparency—was released today in Science, spilling the full experimental details that many experts had sought to suppress out of concern that publishing them could lead to the unleashing of a dangerous virus.

Apr 02, 2012

Apr 02, 2012

Major players weigh implications of NSABB H5N1 reversal

(CIDRAP News) – A federal advisory board's reversal on publishing two controversial H5N1 studies is poised to shift discussions on the topic that continue in London this week, as more participants in the debate weigh in following the Mar 30 announcement.

Jan 31, 2012

Jan 31, 2012

NSABB: Studies show how H5N1 can jump natural barrier

(CIDRAP News) – The core of a US biosecurity advisory board's concern about two controversial, as-yet-unpublished studies on H5N1 viruses is that the studies have shown how to remove the apparent natural barrier that keeps the viruses from spreading efficiently in mammals, members of the board said in statements published today.

Jan 23, 2012

Jan 23, 2012

Experts debate aspects of H5N1 transmission studies

(CIDRAP News) – More experts weighed in recently on various aspects of yet-unpublished H5N1 avian influenza transmissibility studies that have raised concerns about the risk of an intentional or accidental release of the mutant pathogens, as well as worries about scientific censorship.

Dec 23, 2011

Dec 23, 2011

Fears about mutant H5N1 hinge on ferrets as flu model

(CIDRAP News) – In the influenza literature, it's a given that ferrets are the best animal model for influenza in humans. They show similar clinical signs of disease, such as fever, coughing, and sneezing, and flu viruses that spread among humans usually spread in ferrets as well.

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