(CIDRAP News) The US Food and Drug Administration's (FDA's) Pediatric Advisory Committee voted today to recommend stronger label warnings for two antiviral influenza medicationsoseltamivir and zanamivirthat have been linked to reports of neuropsychiatric problems in children and teens, mainly in Japan.
Oseltamivir already carries a warning, but zanamivir currently carries no warning about reported neuropsychiatric effects.
(CIDRAP News) This in-depth article investigates the prospects for development of vaccines to head off the threat of an influenza pandemic posed by the H5N1 avian influenza virus. Its seven parts put advances in vaccine technology in perspective by illuminating the formidable barriers to producing an effective and widely usable vaccine in a short time frame.
Editor's note: This is the last in a seven-part series investigating the prospects for development of vaccines to head off the threat of an influenza pandemic posed by the H5N1 avian influenza virus. The series puts promising advances in vaccine technology in perspective by illuminating the formidable barriers to producing large amounts of an effective and widely usable vaccine in a short time.
(CIDRAP News) The company that markets oseltamivir (Tamiflu) in Japan has announced it will launch new studies to explore whether the antiviral drug contributes to adverse psychiatric and neurologic events in teenagers.
(CIDRAP News) Resistance to oseltamivir (Tamiflu) over the three influenza seasons from 2003 to 2006 remained low in Japan, the country with the world's highest use of the drug, according to a preliminary study from the World Health Organization (WHO).
(CIDRAP News) – Japanese researchers who identified antiviral-resistant strains of influenza B found that they seemed to circulate in communities and families and to make patients just as sick as their nonresistant counterparts did, contrary to a common assumption that resistant flu viruses are likely to be less transmissible and less virulent.
(CIDRAP News) Japan's health ministry today ordered the country's importer of oseltamivir (Tamiflu) to warn doctors against prescribing the drug to teens, because of continuing concerns that psychiatric symptoms might be linked to the influenza medication, according to news services.