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In other developments, research teams describe viral levels in semen and thrombocytopenia as a complication.
The cost study looked at different attack-rate ranges, putting the upper-end estimate at as much as $2 billion.
The Florida study suggests a 'perfect storm' of conditions made Miami a favorable setting for Zika and that mosquito control helped reduce disease levels.
The patients, hospitalized at a speciality center, had a variety of complications and some unusual features.
About 75% of counties on the US mainland have suitable habitat for Aedes mosquitoes, CDC researchers say.
In the past, the city has experienced outbreaks of dengue, Zika, and chikungunya that were spread by Aedes aegypti mosquitoes.
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