WHO attributes 866 million yearly illnesses, 1.5 million deaths around the world to contaminated food

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Today, as the US Food and Drug Administration (FDA) investigates two new outbreaks of foodborne illness, the World Health Organization (WHO) released global data estimating the annual number of illnesses and deaths tied to unsafe food at 866 million and 1.5 million, respectively. 

The WHO report, published in The Lancet Global Health, also found that, despite children younger than 5 years making up only 9% of the population, this age-group represents nearly one third of all cases of foodborne illness—especially deadly diarrheal diseases. 

The analysis assessed 42 major foodborne dangers, including bacteria, viruses, parasites, and chemicals, in 194 countries from 2000 to 2021. For the first time, it also included contamination from metals, rotavirus, and Trypanosoma cruzi (the parasite that carries Chagas disease).

Contamination cost $310 billion in lost productivity in 2021

Most of the roughly 860 million foodborne illnesses recorded in 2021 originated from biological hazards such as non-typhoidal Salmonella enterica, which causes diarrheal illness. That year, however, chemical-contaminated food contributed to an outsized proportion of deaths (73%), with most traced to inorganic arsenic (42%) and lead (31%). The chemicals, which can cause heart disease and cancers, contaminate foods naturally or through human activities.

“Once these substances have entered the food chain, they are often difficult or impossible to remove,” the agency said in a news release. “WHO calls on governments to prevent contamination at the source—through better agricultural practices, stricter industrial controls and stronger environmental regulations.”

Metal contamination of foods has been declining, but the WHO said that these estimates show for the first time the burden of cardiovascular diseases, cancers, and intellectual disability resulting from these exposures. Inorganic arsenic and lead are tied to more than 1 million deaths a year.

WHO calls on governments to prevent contamination at the source—through better agricultural practices, stricter industrial controls and stronger environmental regulations.

“In addition, exposure to chemical hazards such as methylmercury and lead in food can harm the developing brain and cause lifelong neurological and developmental problems in children,” the WHO said.

Also in 2021, foodborne diseases caused 57.1 million disability-adjusted life years, costing about $310 billion in lost productivity and rising to $647 billion when adjusted for cost-of-living differences between countries. 

‘Delay costs lives’

Many cases of foodborne illness could be prevented by cleaner water, improved sanitation and hygiene practices (eg, pasteurization), and better access to healthcare in low-resource areas. 

“Although the total foodborne disease burden has declined since 2000, major regional inequalities persist, with the greatest burden in Africa and South-East Asia,” the WHO said. The African and South-East Asian regions together experience nearly three quarters of global foodborne illnesses and 60% of deaths.

Food safety is not an abstract issue—it touches every meal, every family, every day.

Tedros Adhanom Ghebreyesus, PhD

Foodborne illness causes a burden similar to that from infectious diseases like tuberculosis, HIV/AIDS, and malaria, the authors noted. 

“Food safety is not an abstract issue—it touches every meal, every family, every day,” WHO Director-General Tedros Adhanom Ghebreyesus, PhD, said in the release. “Unsafe food has always been a major public health concern, but until now we lacked the bigger picture of its staggering human and economic toll. These new estimates change that.”

Dietary changes, environmental pressures, globalization, and food-system inequities continue to determine who is most exposed to unsafe food.

“This report is a wake‑up call—but also a roadmap,” said Yuki Minato, WHO technical officer for food safety and senior author of The Lancet Global Health paper. “The data show that foodborne diseases are not only persistent but are being made worse by climate change, which increases contamination risks, and by antimicrobial resistance, which makes infections harder to treat.”

“A One Health approach—integrating human, animal, plant, and environmental health—is essential,” she added. “Countries must act urgently, using these estimates to target interventions, invest in surveillance, and break down the silos between health, agriculture and environment sectors. Delay costs lives.”

US outbreaks involve Listeria, Cyclospora

In the United States, the FDA is trying to find the sources of two new foodborne illness outbreaks, one involving Listeria (eight cases) and one involving Cyclospora (seven).

Details of both outbreaks are scarce. The FDA hasn’t reported the ages or states of the Listeria or Cyclospora patients. The agency has begun traceback efforts but hasn’t named the food being traced.

Listeriosis, which is caused by Listeria monocytogenes bacteria, causes either a mild non-invasive gastrointestinal illness or a life-threatening invasive disease. The former can cause mild symptoms such as fever, achy muscles, nausea and vomiting, and diarrhea, while the latter can cause headache, stiff neck, balance problems, confusion, convulsions, and death.

Cyclosporiasis, an intestinal infection, is caused by the parasite Cyclospora cayetanensis. It causes symptoms such as diarrhea, weight loss, fever, loss of appetite, stomach cramps, bloating, fatigue, and nausea.

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