The US Food and Drug Administration (FDA) yesterday granted emergency use authorization for Simparica Trio as another potential treatment New World screwworm (NWS) infestations in puppies and dogs. This is the latest medication with emergency approval for NWS in canines after the agency approved nitenpyram for dogs and cats in June. The FDA noted the scientific evidence indicates the benefits of Simparica Trio outweigh its risks.
Most dogs in the United States aren’t likely to be exposed to NSW because of where they live. NWS has been found in some areas of Texas and New Mexico. Dogs who traveled to or live in these areas could have a greater chance of contracting NWS. Right now experts urge dog owners to observe their pups for signs of infestations, which includes maggots and foul-smelling wounds or body orifices, such as noses, mouths, or ears.
Simparica Trio has been used in dogs to treat other parasites
Since 2020 Simparica Trio has been FDA-approved to treat heartworms, fleas, and ticks in dogs, and is available only through a prescription from a veterinarian. An active ingredient in the medication, sarolaner, is an antiparasitic drug that has been associated with neurologic complications, including muscle tremors, loss of coordination, and seizures. It’s recommended that veterinarians monitor dogs taking it.
“We want dog owners to be informed, not alarmed,” Timothy Schell, PhD, director of the FDA’s Center for Veterinary Medicine, said in a press release. “The best thing dog owners can do right now is stay aware of the situation, know the signs of infestation, and have a conversation with their veterinarian if they have concerns.”