New CIDRAP program targets chronic wasting disease threat
The University of Minnesota's Center for Infectious Disease Research and Policy (CIDRAP) today announced the launch of the Chronic Wasting Disease Response, Research, and Policy Program (CWD Program) to address the wildlife disease crisis and the potential for zoonotic spread and human-to-human transmission. CIDRAP is the publisher of CIDRAP News.
CWD is a prion disease that affects several cervid species and has been found in at least 26 US states and 3 Canadian provinces. Though no human CWD cases have been detected, many health groups advise against eating meat from animals that have tested positive for CWD.
Michael Osterholm, PhD, MPH, CIDRAP's director and professor in the School of Public Health, said in a University of Minnesota press release that some experts believe human CWD cases linked to contaminated meat may be documented in the years. "There is an immediate and critical need for national leadership on addressing CWD, and the CWD Program establishes the University of Minnesota as both the national and international center for CWD response, research, education and policy," he said.
The program, with support from the university's office of Vice President for Research and office of Vice President for Academic Clinical Affairs, will focus on coordinated and proactive leadership with government agencies and other groups, public education (hunters, healthcare groups, wildlife groups, and policymakers), promotion of rapid testing in cervids, and conduction of primary prevention research.
Mar 19 University of Minnesota press release
FDA requests money to fund food safety technology
In a statement today, Food and Drug Administration (FDA) Commissioner Scott Gottlieb, MD, said the agency has requested funding from President Trump's 2020 budget to fully implement the Food Safety Modernization Act (FSMA).
"We must invest to prevent problems from happening by solidifying the agency's tools under FSMA. We must also embrace new innovations to improve our ability to secure the food supply chain and engage in more effective tracking and tracing of food from farm to fork," Gottlieb said in a statement co-signed by Deputy Commissioner Frank Yiannas, MPH.
The use of whole-genome sequencing (WGS) to identify culprits in foodborne illness outbreaks has greatly increased the number of outbreak investigations in the past few years, Gottlieb said. The FDA investigates approximately 120 potential human food safety outbreak incidents per year and needs increased funds to complete those investigations, he said.
In addition to WGS, the FDA has used more and more blockchain technology to monitor and secure the food supply chain, which also requires additional funding.
"We believe that the additional resources requested from Congress will help our program better protect our nation's food supply and lay the foundation for efforts to create a new era of smarter food safety in which new technologies can provide innovative products, help us better detect outbreaks, and better track and trace foods in the supply chain to prevent contaminated foods from reaching consumers," Gottlieb said.
Mar 19 FDA statement
Anthrax triage checklist designed to help quickly diagnose cases
A study today in the Annals of Internal Medicine used anthrax patient case reports from 1880 through 2013 to develop an initial triage checklist that would help quickly identify the illness in patients during a bioterrorism attack that used Bacillus anthracis, the bacterium that causes anthrax.
Experts from the US Centers for Disease Control and Prevention used medical records from 408 patients who had inhalation, ingestion, or cutaneous anthrax or primary anthrax meningitis, and 657 control patients to establish a checklist that correctly classified 95% of anthrax patients (95% confidence interval [CI], 93% to 97%) without diagnostic testing. The checklist accurately identified controls 76% of the time (CI, 73% to 79%). With the checklist in place, only 5% of anthrax patients required further testing to confirm the bacterial infection.
The progressive checklist contains 12 points, including heart rate, respiratory rate, presence of rash, and headache.
"The screening checklist combines easily collected vital sign data with brief questions on mental function and symptoms; the only physical examination components (required for just 40% of patients in our data set) are observation of cutaneous lesions, auscultation of the lungs, and evaluation for ascites," the authors said.
They concluded that the checklist could be used by both medical and non-medical professionals in a mass casualty setting with confidence.
Mar 19 Ann Intern Med study