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Scientists have identified two mutations usually associated with adaptation to mammals.
The current spurt of cases might be caused by increased circulation of H5N1 in poultry and other factors.
Egypt's health ministry reports 17 more H5N1 to the WHO, indicating continued disease activity.
Egypt has 10 more cases in the past few days, and both Indonesian cases involved likely poultry exposure.
A new H5N1 strain may be associated with a sharp increase in human cases in Egypt.
The WHO said Egyptian authorities reported 30 cases in March alone.
The 7 latest patients in Egypt include a mother and son who got sick on the same day after poultry exposure.
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