Influenza, General

Recent News

Mar 15, 2019
Sick girl in bed

Wave of H3N2 cases keeps US flu activity high

Several indicators show a downward trend, but deaths in kids have reached 68 and hospitalizations continue to climb.

Mar 11, 2019

News Scan for Mar 11, 2019

MERS in Saudi hot spots
Zika pediatric outcomes
WHO global flu strategy
Zoonotic disease guide
Measles in Europe
Mar 08, 2019
Older woman in hospital bed

CDC: Flu activity still high, linked to 8 new kids' deaths

Clinic visits for flulike illness drop a bit, but other major indicators rise.

Mar 05, 2019

News Scan for Mar 05, 2019

FDA chief resigns
MMR vaccine not tied to autism (again)
MERS across Saudi Arabia
Lassa fever decline in Nigeria
Global flu update
Mar 01, 2019
Sick girl in hospital

US flu activity stays high as 15 new deaths in kids reported

Pediatric flu deaths have now reached 56, and activity is widespread nationwide.

Feb 22, 2019
Patient receiving hospital care

CDC: Flu activity reaches new seasonal high

Hospitalization rates are up, and 7 new deaths in kids are reported, raising the season total to 41.

Feb 19, 2019

Flu Scan for Feb 19, 2019

Flu levels up in many regions
Avian flu in India, Africa
Feb 18, 2019

News Scan for Feb 18, 2019

More MERS infections
US flaccid myelitis cases
H9N2 avian flu case in China
Flu A and B illness differences
Human H3N2 flu challenge
Feb 15, 2019
Doctor holding swab

US flu activity continues to rise

Clinic visits for influenza-like illness increased from 4.3% to 4.8%, 6 more pediatric deaths were confirmed, and the H3N2 strain appears to be surging.

Feb 08, 2019
woman sick with flu

CDC: Flu activity hits highest level this season

Flu is widespread in 47 states, and the CDC reports 4 more pediatric flu deaths.

Resources & Literature

Recent Literature

AAP Committee on Infectious Diseases. Recommendations for prevention and control of influenza in children, 2018-2019. Pediatrics 2018 (published online Sep 3)

Abed Y, Fage C, Lague P, et al. Reduced susceptibility to neuraminidase inhibitors in influenza B isolate, Canada. (Research letter) Emerg Infect Dis 2019 (published online Mar 5)

Adlhoch C, Snacken R, Melidou A, et al. Dominant influenza A(H3N2) and B/Yamagata virus circulation in EU/EEA, 2016/17 and 2017/18 seasons, respectively. Euro Surveill 2018 Mar 29;23(13):pii=18-00146

Ali SO, Takas T, Nyborg A, et al. Evaluation of MEDI8852, an anti-influenza A monoclonal antibody, in treating acute uncomplicated influenza. Antimicrob Agents Chemother 2018 (published online Oct 24)

Ali ST, Cowling BJ, Lau EHY, et al. Mitigation of influenza B epidemic with school closures, Hong Kong, 2018. Emerg Infect Dis 2018 (published online Oct 10)

Appiah GD, Chung JR, Flannery B, et al. Hospitalization following outpatient medical care for influenza: US Influenza Vaccine Effectiveness Network, 2011-12—2015-16. Influenza Other Respir Viruses 2018 (published online Nov 8)

Babakazo P, Lubula L, Disasuani W, et al. The national and provincial burden of medically-attended influenza-associated influenza-like-illness and severe acute respiratory illness in the Democratic Republic of Congo, 2013-2015. Influenza Other Respir Viruses 2018 (published online Aug 17)

Belucci TR, Marra AR, Edmond MB, et al. Evaluation of influenza A H1N1 infection and antiviral utilization in a tertiary care hospital. BMC Infect Dis 2018 Nov 16;18:579

Blanton L, Dugan VG, Elal AIA, et al. Influenza activity — United States, September 20, 2018-February 2, 2019. (Update) MMWR 2019 Feb 15;68(6):125-34

Blyth CC, Macartney KK, McRae J, et al. Influenza epidemiology, vaccine coverage and vaccine effectiveness in children admitted to sentinel Australian hospitals in 2017: results from the PAEDS-FluCAN collaboration. Clin Infect Dis 2018 (published online Aug 21)

Bragstad K, Hungnes O, Litleskare I, et al. Community spread and late season increased incidence of oseltamivir-resistant influenza A(H1N1) viruses in Norway 2016. Influenza Other Respir Viruses 2019 (published online Mar 4)

Budd AP, Elal AIA, Alabi N, et al. Influenza Activity—United States, September 30–December 1, 2018. MMWR 2018 Dec 14;67(49):1369-71

Caini S, Spreeuwenberg P, Kusznierz G, et al. Distribution of influenza virus types by age using case-based global surveillance data from twenty-nine countries, 1999-2014. BMC Infect Dis 2018 Jun 8;18:269

Campos ACA, Goes LGB, Moreira-Soto A, et al. Bat influenza A(HL18NL11) virus in fruit bats, Brazil. Emerg Infect Dis 2019 (published online Jan 7)

Cantais A, Mory O, Plat A, et al. Impact of bedside diagnosis of influenza in the paediatric emergency ward. Clin Microbiol Infect 2018 (published online Nov 28)

Chow EJ, Davis T, Abd Elal AI, et al. Influenza activity — United States and worldwide, May 20-October 13, 2018. (Update) MMWR 2018 Oct 26;67(42):1178-85

Cieslak K, Kowalczyk D, Szymanski K, et al. Influenza and influenza-like viruses: frequent infections in children under 14 years of age during the 2016/2017 epidemic season. Adv Exp Med Biol 2018 (published online Aug 17)

Cleary PR, Crofts J, Parry-Ford, F, et al. Characteristics and mortality of severe influenza cases treated with parenteral aqueous zanamivir, United Kingdom, October 2009 to January 2011. Influenza Other Respir Viruses 2018 (published online Aug 23)

Cohen C, Tshangela A, Valley-Omar Z, et al. Household transmission of seasonal influenza from HIV-infected and -uninfected individuals in South Africa, 2013-2014. J Infect Dis 2018 (published online Dec 12)

Coletti P, Poletto C, Turbelin C, et al. Shifting patterns of seasonal influenza epidemics. Sci Rep 2018 (published online Aug 24)

Collins JP, Campbell AP, Openo K, et al. Clinical features and outcomes of immunocompromised children hospitalized with laboratory-confirmed influenza in the United States, 2011-2015. J Pediatr Infect Dis Soc 2018 (published online Oct 25)

Dahlgren FS, Shay DK, Izurieta HS, et. Al. Evaluating oseltamivir prescriptions in Centers for Medicare and Medicaid Services medical claims records as an indicator of seasonal influenza in the United States. Influenza Other Respir Viruses 2018 (published online Mar 25)

Dominguez A, Romero-Tamarit A, Soldevila N, et al. Effectiveness of antiviral treatment in preventing death in severe hospitalised influenza cases over six seasons. Epidemiol Infect 2018 (published online Apr 2)

Dugas AF, Hsieh YH, Lovecchio F, et al. Derivation and validation of a clinical decision guideline for influenza testing in four U.S. emergency departments. Clin Infect Dis 2019 (published online Mar 7)

Ehrenstein V, Kristensen NR, Monz BU, et al. Oseltamivir in pregnancy and birth outcomes. BMC Infect Dis 2018 Oct 16;18:519

Related Practices

Health Matters - pandemic flu issue

Health Matters is a well-written, 8-page newsletter that provides essential information about pandemic influenza to the public. The articles provide essential and practical information about what to expect during a pandemic, and emphasize personal preparedness, prevention, and home care. The document is an ideal tool for placement on desks or web sites at local health departments or distribution at health fairs, clinics, and public presentations.

PIO avian flu functional exercise

The PIO avian flu functional exercise materials were adapted from a public information exercise designed to test the Ohio state communications plan and practice the formation of a joint information center.

"Protect Iowa Health" communications campaign advocates preparedness for everyone

An interactive Web site describes in English and Spanish ways in which anyone can be a preparedness hero.

Pandemic Influenza Planning Kit for Schools

The Planning Kit for Schools has the potential to increase pandemic influenza awareness, assist schools in maintaining continuity of education, and serve as a resource for the greater community. The kit carefully describes tangible steps that schools can take to plan for a pandemic, and the templates require organizations to identify specific school personnel as part of an incident command structure.

Social Distancing Protocol

The Social Distancing Protocol identifies types of social distancing, assesses the probable economic and social impact of each measure, and provides a guide for phased implementation based on WHO pandemic phase and local surveillance. These materials would be useful for review by state and local health departments, because they reference proposed decision-makers at each level of implementation.

Community Readiness Challenge

The Community Readiness Challenge encourages individuals and families to build a pandemic preparedness kit by providing detailed lists of weekly items to buy and ways to prepare for 26 weeks. The LOCC box portion of the program uses business donations to assemble personal preparedness kits for economically-disadvantaged citizens. This practice is noteworthy, because it addresses a group for which there is little focus on prevention and planning efforts.

Prioritization of public health services for pandemic influenza

A local attempt prioritized public health services and determined pertinent parameters for operation during a pandemic. The description of each prioritized service is accompanied by information on the minimum number of staff required to perform the service, necessary products, and ability of staff to perform the service from home. The document could serve as a beginning template for local agencies that have not begun the difficult discussions around public health continuity.

Medical Coordination Centers

A concept paper provides a process by which a public health department can provide statewide accessibility to select medical information and home medical treatment during an influenza pandemic. Existing Medical Coordination Centers (MCCs) are proposed as regional centers for public health operations, such as phone banks, home visit dispatch, provision of medical advice, security, Medical Reserve Corps operations, antiviral dispensing, and EMS coordination.

Caring for the sick at home when it's the only option

The hour-long DVD provides practical, detailed information on caring for ill persons, including those with influenza, at home. It is aimed at non-medical care providers.

Allocating Influenza Vaccines in Minnesota

A well-written and valuable guide on the ethics of influenza vaccine distribution was the product of a multidisciplinary work group composed of public health professionals, ethicists, healthcare providers, and legal experts. The aim of the work group was to provide ethical guidance for Minnesota's statewide pandemic planning efforts, and the group chose to focus on ethical distribution of vaccine as a scarce resource.

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