Clostridium difficile

Recent News

Jan 22, 2019

Stewardship / Resistance Scan for Jan 22, 2019

Antibiotics for respiratory infections
UTI treatment in older adults
Super donors for fecal transplant
Resistant cholera in Ghana
Jan 17, 2019

Stewardship / Resistance Scan for Jan 17, 2019

Antibiotic overprescribing in tots
Fast track for new C diff drug
Jan 14, 2019

Stewardship / Resistance Scan for Jan 14, 2019

Stewardship in English hospitals
Whiff of C diff in pets
Fecal microbiota transplant trial
Dec 19, 2018

Stewardship / Resistance Scan for Dec 19, 2018

Sparse antibiotic use and resistance
Metronidazole for mild C diff
Dec 17, 2018

Stewardship / Resistance Scan for Dec 17, 2018

Drop in children's antibiotic use
C difficile in toilet water
Dec 05, 2018

Stewardship / Resistance Scan for Dec 05, 2018

Severe MRSA in China, Australia
Antibiotic cycling and MRSA, C diff incidence
Antibiotic time-outs
Nov 28, 2018

Stewardship / Resistance Scan for Nov 28, 2018

VRE, MRSA co-colonization in nursing homes
UV disinfection for C diff
Nov 09, 2018

Stewardship / Resistance Scan for Nov 09, 2018

Antibiotics in long-term care facilities
C diff and adverse outcomes
Stewardship in India
Oct 26, 2018

Stewardship / Resistance Scan for Oct 26, 2018

Stewardship to reduce C diff
Declining ear infections, antibiotics
Oct 16, 2018

Stewardship / Resistance Scan for Oct 16, 2018

C difficile on hospital bed sheets
Colistin resistance diagnostics
Dearth of point-of-care tests
New-antibiotic distribution

Resources & Literature

Recent Literature

Aithinne KA, Cooper CW, Lynch RA, et al. Toilet plume aerosol generation rate and environmental contamination following bowl water inoculation with Clostridium difficile spores. Am J Infect Control 2018 (published online Dec 14)

Albert K, Ross B, Calfee DP, et al. Overreporting healthcare-associated C. difficile: a comparison of NHSN LabID with clinical surveillance definitions in the era of molecular testing. Am J Infect Control 2018 (published online Apr 11)

Aldrich AM, Argo T, Koehler TJ, et al. Analysis of treatment outcomes for recurrent Clostridium difficile infections and feca microbiota transplantation in a pediatric hospital. Pediatr Infect Dis J 2019 Jan;38(1):32-6

Appaneal HJ, Caffrey AR, LaPlante KL. What is the role for metronidazole in the treatment of Clostridium difficile infection? Results from a national cohort study of veterans with initial mild disease. Clin Infect Dis 2018 (published online Dec 18)

Barbut F, Day N, Bouee S, et al. Toxigenic Clostridium difficile carriage in general practice: results of a laboratory-based cohort study. Clin Microbiol Infect 2019 (published online Jan 4)

Beinortas T, Burr NE, Wilcox MH, et al. Comparative efficacy of treatments for Clostridium difficile infection: a systematic review and network meta-analysis. Lancet Infect Dis 2018 (published online Jul 16)

Birch T, Golan Y, Rizzardini G, et al. Efficacy of bezlotoxumab based on timing of administration relative to start of antibacterial therapy for Clostridium difficile infection. J Antimicrob Chemother 2018 (published online May 16)

Brite J, McMillen T, Robilotti E, et al. Effectiveness of ultraviolet disinfection in reducing hospital-acquired Clostridium difficile and vancomycin-resistant Enterococcus on a bone marrow transplant unit. Infect Control Hosp Epidemiol 2018 (published online Sep 18)

Casari E, De Luca C, Calabro M, et al. Reducing rates of Clostridium difficile infection by switching to a stand-alone NAAT with clear sampling criteria. Antimicrob Resis Infect Control 2018 Mar 12;7:40

Chaisson LH, Duong D, Cattamanchi A, et al. Association of rapid molecular testing with duration of respiratory isolation for patients with possible tuberculosis in a US hospital. JAMA Intern Med 2018 (published online Aug 27)

Kong LY, Eyre DW, Corbeil J, et al. Clostridium difficile: investigating transmission patterns between infected and colonized patients using whole genome sequencing. Clin Infect Dis 2018 (published online May 28)

Dong D, Ni Q, Wang C, et al. Effects of intestinal colonization by Clostridium difficile and Staphylococcus aureus on microbiota diversity in healthy individuals in China. BMC Infect Dis 2018 May 3;18:207

Dotson KM, Aitken SL, Sofjan AK, et al. Outcomes associated with Clostridium difficile infection in patients with chronic liver disease. Epidemiol Infect 2018 (published online May 9)

Dubberke ER, Lee CH, Orenstein R, et al. Results from a randomized placebo-controlled clinical trial of a RBX2660 — a microbiota-based drug for the prevention of recurrent Clostridium difficile infection. Clin Infect Dis 2018 (published online Mar 29)

Dubberke ER, Reske KA, Hink T, et al. Clostridium difficile colonization among patients with clinically significant diarrhea and no identifiable cause of diarrhea. Infect Control Hosp Epidemiol 2018 (published online Sep 18)

Endres BT, Dotson KM, Poblete K, et al. Environmental transmission of Clostridioides difficile ribotype 027 at a long-term care facility; an outbreak investigation guided by whole genome sequencing. Infect Control Hosp Epidemiol 2018 (published online Sep 2018)

Eyre DW, Davies KA, Davis G, et al. Two distinct patterns of Clostridium difficile diversity across Europe indicates contrasting routes of spread. Clin Infect Dis 2018 (published online Apr 6)

Fabre V, Markou T, Sick-Samuels A, et al. Impact of case-specific education and face-to-face feedback to prescribers and nurses in the management of hospitalized patients with a positive Clostridium difficile test. Open Forum Infect Dis 2018 (published online Sep 10)

Ford CD, Lopansri BK, Webb BJ, et al. Clostridioides difficile colonization and infection in patients with newly diagnosed acute leukemia: incidence, risk factors, and patient outcomes. Am J Infect Control 2018 (published online Nov 22)

Ganetsky A, Han JH, Hughes ME, et al. Oral vancomycin prophylaxis is highly effective in preventing Clostridium difficile infection in allogeneic hematopoietic cell transplant recipients. Clin Infect Dis 2018 (published online Sep 26)

Gerding DN, Kelly CP, Rahav G, et al. Bezlotoxumab for prevention of recurrent C. difficile infection in patients at increased risk for recurrence. Clin Infect Dis 2018 (published online Mar 10)

Grimmond T, Neelakanta A, Miller B, et al. A microbiological study to investigate the carriage and transmission-potential of Clostridium difficile spores on single-use and reusable sharps containers. Am J Infect Control 2018 (published online May 22)

Guh AY, Hatfield KM, Winston LG, et al. Toxin enzyme immunoassays detect Clostridioides difficile infection with greater severity and higher recurrence rates. Clin Infect Dis 2019 (published online Jan 7)

Gupta A, Cifu AS, Khanna S. Diagnosis and treatment of Clostridium difficile infection. JAMA 2018 (published online Aug 27)

Hudson SL, Amoczy G, Gibson H, et al. Probiotic use as prophylaxis for Clostridium difficile-associated diarrhea in a community hospital. Am J Infect Control 2019 (published online Jan 18)

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