Clostridium difficile

Recent News

Nov 17, 2017

Stewardship / Resistance Scan for Nov 17, 2017

Primary care stewardship
No-touch superbug disinfection
Surgical antimicrobial prescribing
Nov 08, 2017

Stewardship / Resistance Scan for Nov 08, 2017

Community-related C diff
Antibiotic sparing for UTIs
Oct 26, 2017
Emergency room care

Antibiotics, EDs linked to community C diff infections

The data show emergency department visits, among other factors, increase C difficile risk.

Oct 24, 2017

News Scan for Oct 24, 2017

Saudi MERS case
Patient movement and C diff
Marburg outbreak details
Monkeypox stigma
Low bioterror readiness
Yellow fever and semen
Oct 06, 2017
Senior dental patient

Study links dental antibiotics to C diff cases

Researchers say better communication about antibiotics is needed, and dentists need to be included in stewardship programs.

Sep 19, 2017

Stewardship / Resistance Scan for Sep 19, 2017

New vaginosis antibiotic
Gene sequencing for CRE
C diff and tetracyclines
Sep 15, 2017

Stewardship / Resistance Scan for Sep 15, 2017

Promising novel assay
Transmissible Enterobacteriaceae
Additional FMT benefits
Sep 12, 2017

Stewardship / Resistance Scan for Sep 12, 2017

Funding for new C diff drug
Antimicrobial resistance in Africa
Sep 06, 2017

Stewardship / Resistance Scan for Sep 06, 2017

Precision antimicrobials
Money for antibiotic development
Canada AMR framework
Pharmacist stewardship
Aug 30, 2017

News Scan for Aug 30, 2017

Saudi MERS cases
New Chagas drug
Avian flu outbreaks
Ebola progression
Cholera in Yemen
High C diff rates

Resources & Literature

Recent Literature

AHRQ. Diagnosis, prevention, and treatment of C. difficile: current state of the evidence. May 30, 2017

Anderson DJ, Chen LF, Weber DJ, et al. Enhanced terminal room disinfection and acquisition and infection caused by multidrug-resistant organisms and Clostridium difficile (the Benefits of Enhanced Terminal Room Disinfection study): a cluster-randomised, multicentre, crossover study. Lancet 2017 (published online Jan 16)

Bernatz JT, Safdar N, Hetzel S, et al.  Antibiotic overuse is a major risk factor for Clostridium difficile infection in surgical patients. Infect Control Hosp Epidemiol 2017 (published online Jul 31)

Borren NZ, Ghadermarzi S, Hutfless S, et al. The emergence of Clostridium difficile infection in Asia: a systematic review and meta-analysis of incidence and impact. PLoS One 2017 May 2;12(5):e0176797

Brown KA, Daneman N, Jones M, et al. The drivers of acute and long-term care C. difficile infection rates: a retrospective multilevel cohort study of 251 facilities. Clin Infect Dis 2017 (published online Jun 8)

Chen Y, Glass K, Liu B, et al. Burden of Clostridium difficile infection: associated hospitalization in a cohort of middle-aged and older adults. Am J Infect Control 2017 (published online Jan 14)

Cheong E, Roberts T, Rattanavong S, et al. Clostridium difficile infection  in the Lao People’s Democratic Republic: first isolation and review of the literature. BMC Infect Dis 2017 Sep 21;17:635

Delgado A, Reveles IA, Cabello FT, et al. Poorer outcomes among cancer patients diagnosed with Clostridium difficile infections in United States community hospitals. BMC Infect Dis 2017 Jun 23;17:448

Deschenes P, Chano F, Dionne LL, et al. Efficacy of the World Health Organization-recommended handwashing technique and a modified washing technique to remove Clostridium difficile from hands. Am J Infect Control 2017 (published online May 16)

Dingle KE, Didelot X, Quan TP, et al. Effects of control interventions on Clostridium difficile infection in England: an observational study. Lancet Infect Dis 2017 (published online Jan 24)

Goda H, Yamaoka H, Nakayama-Imaohji H, et al. Microbicidal effects of weakly acidified chlorous acid water against feline calcivirus and Clostridium difficile spores under protein-rich conditions. PLoS One 2017 May 4;12(5):e0176718

Gross AE, Johannes RS, Gupta V, et al. The effect of a piperacillin/tazobactam shortage on antimicrobial prescribing and Clostridium difficile risk in 88 U.S. medical centers. Clin Infect Dis 2017 (published online Apr 24)

Grzeskowiak L, Martinez-Vallespin B, Dadi TH, et al. Formula-feeding predisposes neonatal piglets to Clostridium difficile gut infection. J Infect Dis 2017 (published online Nov 1)

Hiensch R, Poeran J, Saunders-Hao P, et al. Impact of an electronic sepsis initiative on antibiotic use and health care facility-onset Clostridium difficile infection rates. Am J Infect Control 2017 (published online Jun 8)

Hocquart M, Lagier JC, Cassir N, et al. Early faecal microbiota transplantation improves survival in severe Clostridium difficile infections. Clin Infect Dis 2017 (published online Aug 24)

Hung YP, Huang IH, Lin HJ, et al. Predominance of Clostridium difficile ribotypes 017 and 078 among toxigenic clinical isolates in Southern Taiwan. PLoS One 2016 Nov 18;11(11):e0166159

Kenters N, Huijskens EGW, de Wit SCJ, et al. Effectiveness of various cleaning and disinfectant products on Clostridium difficile spores of PCR ribotypes 010, 014 and 027. Antimicrob Resist Infect Control 2017 June 2;6:54

Krishna A, Pervaiz A, Lephart P, et al. Prevalence of Clostridium difficile infection in acute care hospitals, long-term care facilities, and outpatient clinics: is Clostridium difficile infection underdiagnosed in long-term care facility patients? Am J Infect Control 2017 (published online Jun 8)

Ma GK, Brensinger CM, Wu Q, et al. Increasing incidence of multiply recurrent Clostridium difficile infection in the United States: a cohort study. Ann Intern Med 2017 (published online Jul 4)

Murray SG, Yim JWL, Croci R, et al. Using spatial and temporal mapping to identify nosocomial disease transmission of Clostridium difficile. (Letter) JAMA Intern Med 2017 (published online Oct 23)

Na'amnih W, Adler A, Miller-Roll T, et al. Incidence and risk factors for community and hospital acquisition of Clostridium difficile infection in the Tel Aviv Sourasky Medical Center. Infect Control Hosp Epidemiol 2017 (published online May 31)

Nanwa N, Sander B, Krahn M, et al. A population-based matched cohort study examining the mortality and costs of patients with community-onset Clostridium difficile infection identified using emergency department visits and hospital admissions. PLoS One 2017 Mar 3;12(3):e0172410

Nelson RL, Suda KJ, Evans CT. Antibiotic treatment for Clostridium difficile-associated diarrhoea in adults. Cochrane Libr 2017 (published online Mar 3)

Orden C, Neila C, Blanco JL, et al. Recreational sandboxes for children and dogs can be a source of epidemic ribotypes of Clostridium difficile. Zoonoses Public Health 2017 (published online Jul 7) 

Putsathit P, Maneerattanaporn M, Piewngam P, et al. Antimicrobial susceptibility of Clostridium difficile isolated in Thailand. Antimicrob Resist Infect Control 2017 (published online Jun 8)

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