Clostridium difficile

Recent News

Jan 10, 2018

Stewardship / Resistance Scan for Jan 10, 2018

C difficile decline
Antibiotics in nursing homes
Environmental health risks
Jan 04, 2018

News Scan for Jan 04, 2018

Sexually transmitted Zika
Sanofi fined
Typhoid vaccine
Non-vaccinating parents
Real-time C diff alert
Dec 20, 2017

Stewardship / Resistance Scan for Dec 20, 2017

Long-term FMT success
Antibiotic choice for C diff
Dec 15, 2017
Doctor writing in patient's chart

Experts call for new approach to regulating fecal transplants

A 3-track system would offer key advantages to the FDA's approach, the experts say.

Dec 04, 2017

News Scan for Dec 04, 2017

H7N9, H9N2 cases in China
Saudi MERS cases
Salmonella in melons
Bats and filoviruses
C diff vaccine axed
Nov 28, 2017
Oral capsule

Fecal transplant by capsule may match colonoscopy for C diff

Rates of prevention of recurrent C diff were similar, with fewer side effects.

Nov 27, 2017

Stewardship / Resistance Scan for Nov 27, 2017

Protecting the gut from antibiotics
Cost of C diff in kids
MDR-TB in Europe
Nov 22, 2017

Stewardship / Resistance Scan for Nov 22, 2017

C diff and stewardship
Clinical decision support
EMR protocol and C diff rates
Nov 17, 2017

Stewardship / Resistance Scan for Nov 17, 2017

Primary care stewardship
No-touch superbug disinfection
Surgical antimicrobial prescribing
Nov 08, 2017

Stewardship / Resistance Scan for Nov 08, 2017

Community-related C diff
Antibiotic sparing for UTIs

Resources & Literature

Recent Literature

AHRQ. Diagnosis, prevention, and treatment of C. difficile: current state of the evidence. May 30, 2017

Bernatz JT, Safdar N, Hetzel S, et al.  Antibiotic overuse is a major risk factor for Clostridium difficile infection in surgical patients. Infect Control Hosp Epidemiol 2017 (published online Jul 31)

Borren NZ, Ghadermarzi S, Hutfless S, et al. The emergence of Clostridium difficile infection in Asia: a systematic review and meta-analysis of incidence and impact. PLoS One 2017 May 2;12(5):e0176797

Brown KA, Daneman N, Jones M, et al. The drivers of acute and long-term care C. difficile infection rates: a retrospective multilevel cohort study of 251 facilities. Clin Infect Dis 2017 (published online Jun 8)

Bruno-Murtha LA, Osgood RA, Alexandre CE. A successful strategy to decrease hospital-onset Clostridium difficile. Infect Control Hosp Epidemiol 2018 (published online Jan 5)

Cheong E, Roberts T, Rattanavong S, et al. Clostridium difficile infection  in the Lao People’s Democratic Republic: first isolation and review of the literature. BMC Infect Dis 2017 Sep 21;17:635

Delgado A, Reveles IA, Cabello FT, et al. Poorer outcomes among cancer patients diagnosed with Clostridium difficile infections in United States community hospitals. BMC Infect Dis 2017 Jun 23;17:448

Deschenes P, Chano F, Dionne LL, et al. Efficacy of the World Health Organization-recommended handwashing technique and a modified washing technique to remove Clostridium difficile from hands. Am J Infect Control 2017 (published online May 16)

Dingle KE, Didelot X, Quan TP, et al. Effects of control interventions on Clostridium difficile infection in England: an observational study. Lancet Infect Dis 2017 (published online Jan 24)

Goda H, Yamaoka H, Nakayama-Imaohji H, et al. Microbicidal effects of weakly acidified chlorous acid water against feline calcivirus and Clostridium difficile spores under protein-rich conditions. PLoS One 2017 May 4;12(5):e0176718

Gross AE, Johannes RS, Gupta V, et al. The effect of a piperacillin/tazobactam shortage on antimicrobial prescribing and Clostridium difficile risk in 88 U.S. medical centers. Clin Infect Dis 2017 (published online Apr 24)

Grzeskowiak L, Martinez-Vallespin B, Dadi TH, et al. Formula-feeding predisposes neonatal piglets to Clostridium difficile gut infection. J Infect Dis 2017 (published online Nov 1)

Guery B, Menichetti F, Anttila VJ, et al. Extended-pulsed fidaxomicin versus vancomycin for Clostridium difficile infection in patients 60 years and older (EXTEND): a randomised, controlled, open-label, phase 3b/4 trial. Lancet Infect Dis 2017 (published online Dec 19)

Guh AY, Mu Y, Baggs J, et al. Trends in incidence of long-term-care facility onset Clostridium difficile infections in 10 US geographic locations during 2011-2015. Am J Infect Control 2018 (published online Jan 9)

Hiensch R, Poeran J, Saunders-Hao P, et al. Impact of an electronic sepsis initiative on antibiotic use and health care facility-onset Clostridium difficile infection rates. Am J Infect Control 2017 (published online Jun 8)

Hocquart M, Lagier JC, Cassir N, et al. Early faecal microbiota transplantation improves survival in severe Clostridium difficile infections. Clin Infect Dis 2017 (published online Aug 24)

Kenters N, Huijskens EGW, de Wit SCJ, et al. Effectiveness of various cleaning and disinfectant products on Clostridium difficile spores of PCR ribotypes 010, 014 and 027. Antimicrob Resist Infect Control 2017 June 2;6:54

Krishna A, Pervaiz A, Lephart P, et al. Prevalence of Clostridium difficile infection in acute care hospitals, long-term care facilities, and outpatient clinics: is Clostridium difficile infection underdiagnosed in long-term care facility patients? Am J Infect Control 2017 (published online Jun 8)

Ma GK, Brensinger CM, Wu Q, et al. Increasing incidence of multiply recurrent Clostridium difficile infection in the United States: a cohort study. Ann Intern Med 2017 (published online Jul 4)

Mamo Y, Woodworth MH, Wang T, et al. Durability and long-term clinical outcomes of fecal microbiota transplant (FMT) treatment in patients with recurrent Clostridium difficile infection. Clin Infect Dis 2017 (published online Dec 19)

Mehrotra P, Jang J, Gidengil C, et al. Attributable cost of Clostridium difficile infection in pediatric patients. Infect Control Hosp Epidemiol 2017 (published online Nov 27)

Murray SG, Yim JWL, Croci R, et al. Using spatial and temporal mapping to identify nosocomial disease transmission of Clostridium difficile. (Letter) JAMA Intern Med 2017 (published online Oct 23)

Na'amnih W, Adler A, Miller-Roll T, et al. Incidence and risk factors for community and hospital acquisition of Clostridium difficile infection in the Tel Aviv Sourasky Medical Center. Infect Control Hosp Epidemiol 2017 (published online May 31)

Nanwa N, Sander B, Krahn M, et al. A population-based matched cohort study examining the mortality and costs of patients with community-onset Clostridium difficile infection identified using emergency department visits and hospital admissions. PLoS One 2017 Mar 3;12(3):e0172410

Nelson RL, Suda KJ, Evans CT. Antibiotic treatment for Clostridium difficile-associated diarrhoea in adults. Cochrane Libr 2017 (published online Mar 3)

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