Diagnostics

Recent News

Mar 26, 2019

News Scan for Mar 26, 2019

Limits of rapid diagnostics
Measles in Michigan, NY
More Lassa in Nigeria
Mar 14, 2019

Stewardship / Resistance Scan for Mar 14, 2019

MRSA in hospital roaches
Test for resistant gonorrhea
German funding for CARB-X
Feb 26, 2019

News Scan for Feb 26, 2019

Diagnostic tests in an emergency
CWD expansion in Kansas
Brazil chikungunya arrival
Feb 18, 2019
Baby with fever

Model derived to rule out bacteria in feverish infants

A protocol involving urinalysis, absolute neutrophil count, and procalcitonin levels showed 97.7% sensitivity and 60.0% specificity.

Feb 15, 2019

Stewardship / Resistance Scan for Feb 15, 2019

Electronic stewardship intervention
Antibiotic resistance and UTI risk
C diff testing in children
Jan 24, 2019

Stewardship / Resistance Scan for Jan 24, 2019

Antibiotic-resistant Brucella
New STI test cleared
KFC fulfills antibiotics pledge
Dec 21, 2018

Stewardship / Resistance Scan for Dec 21, 2018

Rapid meningitis tests
Novel pneumonia antibiotic
Dec 11, 2018

Stewardship / Resistance Scan for Dec 11, 2018

Susceptibility testing platforms
De-escalation and patient outcome
Highly concerning ICU sepsis
Resistant Klebsiella in pets, people
Nov 29, 2018

Stewardship / Resistance Scan for Nov 29, 2018

Antibiotics after rhinoplasty
Rapid flu diagnostic tests
CDC funding for AMR initiatives
Nov 02, 2018

News Scan for Nov 02, 2018

Polio in 4 countries
Avian flu in Minnesota, Vietnam
Testing for very resistant TB
New CWD type in moose?

Resources & Literature

Recent Literature

Abbas S, Bernard S, Lee KB, et al. Rapid respiratory panel testing: impact of active antimicrobial stewardship. Am J Infect Control 2018 (published online Oct 30)

Abubakar I, Drobnieswki F, Southern J, et al. Prognostic value of interferon-gamma release assays and tuberculin skin test in predicting the development of active tuberculosis (UK PREDICT TB): a prospective cohort study. Lancet Infect Dis 2018 (published online Aug 30)

Althaus T, Greer RC, Swe MMM, et al. Effect of point-of-care C-reactive protein testing on antibiotic prescription in febrile patients attending primary care in Thailand and Myanmar: an open-label, randomised, controlled trial. Lancet 2019 J;7(1):PE119-3

Aurelie C, Bonacorsi S, Truong J, et al. Detection of carbapenemases-producing Enterobacteriaceae in positive blood culture using Immunochromatographic RESIST-4 O.K.N.V assay. Antimicrob Agents Chemother 2018 (published online Sep 24)

Barnes GK, Gudina EK, Berhane M, et al. New molecular tools for meningitis diagnostics in Ethiopia – a necessary step towards improving antimicrobial prescription. BMC Infect Dis 2018 (published online Dec 20)

Bellew S, Grijalva CG, Williams DJ, et al. Pneumococcal and Legionella urinary antigen tests in community-acquired pneumonia: prospective evaluation of indications for testing. Clin Infect Dis 2018 (published online Sep 28)

Benirschke RC, McElvania E, Thomson R, et al. Clinical impact of rapid point-of-care polymerase chain reaction influenza testing in an urgent care setting: a single center study. J Clin Microbiol 2019 (published online Jan 2)

Bulabula ANH, Nelson JA, Musafiri EM, et al. Prevalence, predictors, and successful treatment outcomes of Xpert MTB/RIF-identified rifampicin-resistant tuberculosis in post-conflict eastern Democratic Republic of the Congo, 2012-2017: a retrospective province-wide cohort study. Clin Infect Dis 2019 (published online Feb 12)

Buss BA, Baures TJ, Yoo M, et al. Impact of a multiplex PCR assay for bloodstream infections with and without antimicrobial stewardship intervention at a cancer hospital. Open Forum Infect Dis 2018 (published online Oct 10)

Buss CG, Dudani JS, Akana RTK, et al. Protease activity sensors noninvasively classify bacterial infections and antibiotic responses. Ebio Medicine 2018 (published online Nov 29)

Cantais A, Mory O, Plat A, et al. Impact of bedside diagnosis of influenza in the paediatric emergency ward. Clin Microbiol Infect 2018 (published online Nov 28)

Chaisson LH, Duong D, Cattamanchi A, et al. Association of rapid molecular testing with duration of respiratory isolation for patients with possible tuberculosis in a US hospital. JAMA Intern Med 2018 Oct;178(10):1380-8

Cheaveau J, Nguyen H, Chow B, et al. Clinical validation of a commercial LAMP test for ruling out malaria in returning travelers: a prospective diagnostic trial. Open Forum Infect Dis 2018 (published online Oct 12)

Coppens J, Van Heirstraeten L, Ruzin A, et al. Comparison of GeneXpert MRSA/SA ETA assay with semi-quantitative and quantitative cultures and nuc gene-based qPCR for detection of Staphylococcus aureus in endotracheal aspirate samples. Antimicrob Resist Infect Control 2019 Jan 5;8:4

DeDiodato G, Bradbury N. Cerebrospinal fluid analysis with the BioFire FilmArray meningitis/encephalitis molecular panel reduces length of hospital stay in patients with suspected central nervous system infections. Open Forum Infect Dis 2019 (published online Mar 5)

Dou M, Macias N, Shen F, et al. Rapid and accurate diagnosis of the respiratory disease pertussis on a point-of-care biochip. EClinicalMedicine 2019 (published online Mar 5)

Dumont E, Vergalli J, Conraux L, et al. Antibiotics and efflux: combined spectrofluorimetry and mass spectrometry to evaluate the involvement of concentratin and efflux activity in antibiotic intracellular accumulation. J Antimicrob Chemother 2018 (published online Oct 15)

ECDC. Expert consensus protocol on colistin resistance detection and characterization for the survey of carbapenem- and/or colistin-resistant Enterobacteriaceae. Jan 14, 2019

Ellis O, Hemarajata P, Shahkolahi A, et al. A multi-site implementation of a real-time polymerase chain reaction assay to predict ciprofloxacin susceptibility in Neisseria gonorrhoeae. Diagn Microbiol Infect Dis 2019 (published online Jan 14)

Fauconnier C, Dodemont M, Depouhon A, et al. Lateral flow immunochromatographic assay for rapid screening of faecal carriage of carbapenemase-producing Enterobacteriaceae. J Antimicrob Chemother 2018 (published online Oct 30)

Feng ZS, Zhao L, Wang J, et al. A multiplex one-tube nested real time RT-PCR assay for simultaneous detection of respiratory syncytial virus, human rhinovirus and human metapneumovirus. Virol J 2018 Oct 30;15:167

Girlich D, Naas T, Dortet L. Comparison of the Superpolymyxin and CHROMID Colistin R screening media for the detection of colistin-resistant Enterobacteriaceae from spiked rectal swabs. Antimicrob Agents Chemother 2018 (published online Oct 15)

Girma S, Cheaveau J, Mohon AN, et al. Prevalence and epidemiological characteristics of asymptomatic malaria based on ultrasensitive diagnostics: a cross-sectional study. Clin Infect Dis 2018 (published online Nov 26)

Guo LU, Li YJ, Liu LL, et al. Detection of pediatric bacterial meningitis pathogens from cerebrospinal fluid by next-generation sequencing technology. J Infection 2018 (published online Dec 11)

Henritzi D, Hoffmann B, Wacheck S, et al. A newly developed tetraplex real time RT‐PCR for simultaneous screening of influenza virus types A, B, C and D. Influenza Other Respir Viruses 2018 (published online Sep 28)

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