Diagnostics

Recent News

Dec 21, 2018

Stewardship / Resistance Scan for Dec 21, 2018

Rapid meningitis tests
Novel pneumonia antibiotic
Dec 11, 2018

Stewardship / Resistance Scan for Dec 11, 2018

Susceptibility testing platforms
De-escalation and patient outcome
Highly concerning ICU sepsis
Resistant Klebsiella in pets, people
Nov 29, 2018

Stewardship / Resistance Scan for Nov 29, 2018

Antibiotics after rhinoplasty
Rapid flu diagnostic tests
CDC funding for AMR initiatives
Nov 02, 2018

News Scan for Nov 02, 2018

Polio in 4 countries
Avian flu in Minnesota, Vietnam
Testing for very resistant TB
New CWD type in moose?
Oct 25, 2018

Flu Scan for Oct 25, 2018

H3N2v flu and risk groups
Flu, strep rapid tests
H5N6 in Chinese poultry
Oct 24, 2018
Microbes

New test detects 100s of bacteria, resistance genes

Bacterial reads for unexplained sepsis were 1,000 times higher than with a different assay.

Oct 18, 2018

Stewardship / Resistance Scan for Oct 18, 2018

Rapid susceptibility tests
AMR surveillance in South Korea
Biomarkers and sepsis management
Oct 16, 2018

Stewardship / Resistance Scan for Oct 16, 2018

C difficile on hospital bed sheets
Colistin resistance diagnostics
Dearth of point-of-care tests
New-antibiotic distribution
Oct 05, 2018
clinic prescription

Study: Outpatient antibiotics widely prescribed without an infection diagnosis

The new study sheds light on prescribing missed in other studies, including for conditions without an in-patient visit.

Oct 04, 2018

Stewardship / Resistance Scan for Oct 04, 2018

Bacteriophage clinical trial
Improper antibiotic prescribing in China
Point-of-care flu tests and antibiotics

Resources & Literature

Recent Literature

Abbas S, Bernard S, Lee KB, et al. Rapid respiratory panel testing: impact of active antimicrobial stewardship. Am J Infect Control 2018 (published online Oct 30)

Abubakar I, Drobnieswki F, Southern J, et al. Prognostic value of interferon-gamma release assays and tuberculin skin test in predicting the development of active tuberculosis (UK PREDICT TB): a prospective cohort study. Lancet Infect Dis 2018 (published online Aug 30)

Althaus T, Greer RC, Swe MMM, et al. Effect of point-of-care C-reactive protein testing on antibiotic prescription in febrile patients attending primary care in Thailand and Myanmar: an open-label, randomised, controlled trial. Lancet 2019 J;7(1):PE119-3

Aurelie C, Bonacorsi S, Truong J, et al. Detection of carbapenemases-producing Enterobacteriaceae in positive blood culture using Immunochromatographic RESIST-4 O.K.N.V assay. Antimicrob Agents Chemother 2018 (published online Sep 24)

Barnes GK, Gudina EK, Berhane M, et al. New molecular tools for meningitis diagnostics in Ethiopia – a necessary step towards improving antimicrobial prescription. BMC Infect Dis 2018 (published online Dec 20)

Bellew S, Grijalva CG, Williams DJ, et al. Pneumococcal and Legionella urinary antigen tests in community-acquired pneumonia: prospective evaluation of indications for testing. Clin Infect Dis 2018 (published online Sep 28)

Benirschke RC, McElvania E, Thomson R, et al. Clinical impact of rapid point-of-care polymerase chain reaction influenza testing in an urgent care setting: a single center study. J Clin Microbiol 2019 (published online Jan 2)

Buss BA, Baures TJ, Yoo M, et al. Impact of a multiplex PCR assay for bloodstream infections with and without antimicrobial stewardship intervention at a cancer hospital. Open Forum Infect Dis 2018 (published online Oct 10)

Buss CG, Dudani JS, Akana RTK, et al. Protease activity sensors noninvasively classify bacterial infections and antibiotic responses. Ebio Medicine 2018 (published online Nov 29)

Cantais A, Mory O, Plat A, et al. Impact of bedside diagnosis of influenza in the paediatric emergency ward. Clin Microbiol Infect 2018 (published online Nov 28)

Chaisson LH, Duong D, Cattamanchi A, et al. Association of rapid molecular testing with duration of respiratory isolation for patients with possible tuberculosis in a US hospital. JAMA Intern Med 2018 Oct;178(10):1380-8

Cheaveau J, Nguyen H, Chow B, et al. Clinical validation of a commercial LAMP test for ruling out malaria in returning travelers: a prospective diagnostic trial. Open Forum Infect Dis 2018 (published online Oct 12)

Coppens J, Van Heirstraeten L, Ruzin A, et al. Comparison of GeneXpert MRSA/SA ETA assay with semi-quantitative and quantitative cultures and nuc gene-based qPCR for detection of Staphylococcus aureus in endotracheal aspirate samples. Antimicrob Resist Infect Control 2019 Jan 5;8:4

Dumont E, Vergalli J, Conraux L, et al. Antibiotics and efflux: combined spectrofluorimetry and mass spectrometry to evaluate the involvement of concentratin and efflux activity in antibiotic intracellular accumulation. J Antimicrob Chemother 2018 (published online Oct 15)

ECDC. Expert consensus protocol on colistin resistance detection and characterization for the survey of carbapenem- and/or colistin-resistant Enterobacteriaceae. Jan 14, 2019

Ellis O, Hemarajata P, Shahkolahi A, et al. A multi-site implementation of a real-time polymerase chain reaction assay to predict ciprofloxacin susceptibility in Neisseria gonorrhoeae. Diagn Microbiol Infect Dis 2019 (published online Jan 14)

Fauconnier C, Dodemont M, Depouhon A, et al. Lateral flow immunochromatographic assay for rapid screening of faecal carriage of carbapenemase-producing Enterobacteriaceae. J Antimicrob Chemother 2018 (published online Oct 30)

Feng ZS, Zhao L, Wang J, et al. A multiplex one-tube nested real time RT-PCR assay for simultaneous detection of respiratory syncytial virus, human rhinovirus and human metapneumovirus. Virol J 2018 Oct 30;15:167

Girlich D, Naas T, Dortet L. Comparison of the Superpolymyxin and CHROMID Colistin R screening media for the detection of colistin-resistant Enterobacteriaceae from spiked rectal swabs. Antimicrob Agents Chemother 2018 (published online Oct 15)

Girma S, Cheaveau J, Mohon AN, et al. Prevalence and epidemiological characteristics of asymptomatic malaria based on ultrasensitive diagnostics: a cross-sectional study. Clin Infect Dis 2018 (published online Nov 26)

Guo LU, Li YJ, Liu LL, et al. Detection of pediatric bacterial meningitis pathogens from cerebrospinal fluid by next-generation sequencing technology. J Infection 2018 (published online Dec 11)

Henritzi D, Hoffmann B, Wacheck S, et al. A newly developed tetraplex real time RT‐PCR for simultaneous screening of influenza virus types A, B, C and D. Influenza Other Respir Viruses 2018 (published online Sep 28)

Hofmann NE, Moniz CA, Holzschuh A, et al. Diagnostic performance of conventional RDT and ultra-sensitive RDT for malaria diagnosis in febrile outpatients in Tanzania. J Infect Dis 2018 (published online Nov 24)

Hopkins KL, Meunier D, Naas T, et al. Evaluation of the NG-test CARBA 5 multiplex immunochromatograhic assay for the detection of KPC, OXA-48-like, NDM, VIM and IMP carbapenemases. J Antimicrob Chemother 2018 (published online Sep 5)

Hou X, Lee A, Jimenez-Ortigosa C, et al. Rapid detection of ERG11-associated azole resistance and FKS-associated echinocandin resistance in Candida auris. Antimicrob Agents Chemother 2018 (published online Nov 5)

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