Diagnostics

Recent News

Nov 02, 2018

News Scan for Nov 02, 2018

Polio in 4 countries
Avian flu in Minnesota, Vietnam
Testing for very resistant TB
New CWD type in moose?
Oct 25, 2018

Flu Scan for Oct 25, 2018

H3N2v flu and risk groups
Flu, strep rapid tests
H5N6 in Chinese poultry
Oct 24, 2018
Microbes

New test detects 100s of bacteria, resistance genes

Bacterial reads for unexplained sepsis were 1,000 times higher than with a different assay.

Oct 18, 2018

Stewardship / Resistance Scan for Oct 18, 2018

Rapid susceptibility tests
AMR surveillance in South Korea
Biomarkers and sepsis management
Oct 16, 2018

Stewardship / Resistance Scan for Oct 16, 2018

C difficile on hospital bed sheets
Colistin resistance diagnostics
Dearth of point-of-care tests
New-antibiotic distribution
Sep 28, 2018
Smart phone microbe diagnostics

Smartphone-based test shows promise for rapid UTI diagnosis

Research on the device indicates it has the potential to provide quick, low-cost diagnostics.

Sep 27, 2018
DNA test genetic sequencing

Study heralds genetic era of TB drug susceptibility testing

Whole-genome sequencing could lead to faster, more accurate resistance testing.

Sep 17, 2018

Stewardship / Resistance Scan for Sep 17, 2018

Azithromycin resistance in N gonorrhoeae
UK antibiotic prescribing
Viral diagnostic shows promise
MDR urinary tract infections
Aug 28, 2018

News Scan for Aug 28, 2018

MERS vaccine partnership
Molecular TB testing
H5N1 avian flu in Malaysia
Aug 28, 2018

Stewardship / Resistance Scan for Aug 28, 2018

New antibiotic for intra-abdominal infections
Web training for antibiotic stewardship
Chest x-ray and pneumonia

Resources & Literature

Recent Literature

Abbas S, Bernard S, Lee KB, et al. Rapid respiratory panel testing: impact of active antimicrobial stewardship. Am J Infect Control 2018 (published online Oct 30)

Abubakar I, Drobnieswki F, Southern J, et al. Prognostic value of interferon-gamma release assays and tuberculin skin test in predicting the development of active tuberculosis (UK PREDICT TB): a prospective cohort study. Lancet Infect Dis 2018 (published online Aug 30)

Aurelie C, Bonacorsi S, Truong J, et al. Detection of carbapenemases-producing Enterobacteriaceae in positive blood culture using Immunochromatographic RESIST-4 O.K.N.V assay. Antimicrob Agents Chemother 2018 (published online Sep 24)

Bellew S, Grijalva CG, Williams DJ, et al. Pneumococcal and Legionella urinary antigen tests in community-acquired pneumonia: prospective evaluation of indications for testing. Clin Infect Dis 2018 (published online Sep 28)

Buss BA, Baures TJ, Yoo M, et al. Impact of a multiplex PCR assay for bloodstream infections with and without antimicrobial stewardship intervention at a cancer hospital. Open Forum Infect Dis 2018 (published online Oct 10)

Chaisson LH, Duong D, Cattamanchi A, et al. Association of rapid molecular testing with duration of respiratory isolation for patients with possible tuberculosis in a US hospital. JAMA Intern Med 2018 Oct;178(10):1380-8

Cheaveau J, Nguyen H, Chow B, et al. Clinical validation of a commercial LAMP test for ruling out malaria in returning travelers: a prospective diagnostic trial. Open Forum Infect Dis 2018 (published online Oct 12)

Dumont E, Vergalli J, Conraux L, et al. Antibiotics and efflux: combined spectrofluorimetry and mass spectrometry to evaluate the involvement of concentratin and efflux activity in antibiotic intracellular accumulation. J Antimicrob Chemother 2018 (published online Oct 15)

Fauconnier C, Dodemont M, Depouhon A, et al. Lateral flow immunochromatographic assay for rapid screening of faecal carriage of carbapenemase-producing Enterobacteriaceae. J Antimicrob Chemother 2018 (published online Oct 30)

Feng ZS, Zhao L, Wang J, et al. A multiplex one-tube nested real time RT-PCR assay for simultaneous detection of respiratory syncytial virus, human rhinovirus and human metapneumovirus. Virol J 2018 Oct 30;15:167

Girlich D, Naas T, Dortet L. Comparison of the Superpolymyxin and CHROMID Colistin R screening media for the detection of colistin-resistant Enterobacteriaceae from spiked rectal swabs. Antimicrob Agents Chemother 2018 (published online Oct 15)

Henritzi D, Hoffmann B, Wacheck S, et al. A newly developed tetraplex real time RT‐PCR for simultaneous screening of influenza virus types A, B, C and D. Influenza Other Respir Viruses 2018 (published online Sep 28)

Hopkins KL, Meunier D, Naas T, et al. Evaluation of the NG-test CARBA 5 multiplex immunochromatograhic assay for the detection of KPC, OXA-48-like, NDM, VIM and IMP carbapenemases. J Antimicrob Chemother 2018 (published online Sep 5)

Hou X, Lee A, Jimenez-Ortigosa C, et al. Rapid detection of ERG11-associated azole resistance and FKS-associated echinocandin resistance in Candida auris. Antimicrob Agents Chemother 2018 (published online Nov 5)

Koehler JW, Douglas CE, Minogue TD. A highly multiplexed broad pathogen detection assay for infectious disease diagnostics. PLOS Negl Trop Dis 2018 Nov 5;12(11):e0006889

Li J, Tao Y, Tang M, et al. Rapid detection of respiratory organisms with the FilmArray respiratory panel in a large children's hospital in China. BMC Infect Dis 2018 Oct 11;18:510

Meunier D, Woodford N, Hopkins KL. Evaluation of the AusDiagnostics MT CRE EU assay for the detection of carbapenemase genes and transferable colistin resistance determinants mcr-1/-2 in MDR gram-negative bacteria. J Antimicrob Chemother 2018 (published online Sep 5)

Nishimura T, Ota M, Mori M, et al. Estimating latent tuberculosis infection using interferon-gamma release assay, Japan. Emerg Infect Dis 2018 Nov;24(11)

Pollock NR, Banz A, Chen X, et al. Comparison of C. difficile stool toxin concentrations in adults with symptomatic infection and asymptomatic carriage using an ultrasensitive quantitative immunoassay. Clin Infect Dis 2018 (published online May 17)

Porter AM, Bland CM, Young HN, et al. Comparison of pharmacist-directed management of multiplex PCR blood culture results with conventional microbiology methods on effective and optimal therapy within a community hospital. Antimicrob Agents Chemother 2018 (published online Oct 15)

Ranjbar R, Farsani FY, Dehkordi FS. Phenotypic analysis of antibiotic resistance and genotypic study of the vacA, cagA, iceA, oipA and babA genotypes of the Helicobacter pylori strains isolated from raw milk. Antimicrob Resist Infect Control 2018 Sep 29;7:118

Sauget M, Bertrand X, Hocquet D. Rapid antibiotic susceptibility testing on blood cultures using MALDI-TOF MS. PLoS One 2018 Oct 11;13(10):e0205603

Tamburini FB, Andermann TM, Tkachenko E, et al. Precision identification of diverse bloodstream pathogens in the gut microbiome. Nat Med 2018 (published online Oct 15)

Tamma PD, Fan Y, Bergman Y, et al. Applying rapid whole genome sequencing to predict phenotypic antimicrobial susceptibility testing results among carbapenem-resistant Klebsiella pneumoniae clinical isolates. Antimicrob Agents Chemother 2018 (published online 29)

Tilton CS, Johnson SW. Development of a risk prediction model for hospital-onset Clostridium difficile infection in patients receiving systemic antibiotics. Am J Infect Control 2018 (published online Oct 11)

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