H7N9 Avian Influenza

Recent News

May 17, 2016

News Scan for May 17, 2016

MERS details
H7N9 cases in China
Yellow fever emergency panel
Salmonella tied to greens
Global meningitis seasonality
May 13, 2016

News Scan for May 13, 2016

Sprout outbreak winds down
H7N9 severity shifts
May 11, 2016

News Scan for May 11, 2016

Animal-antibiotic sales
H7N9 infections in China
Polio case in Nigeria
DTaP delays and pertussis
Apr 19, 2016

News Scan for Apr 19, 2016

Public health funding
Saudi MERS cases
More chikungunya
New H7N9 cases
MRSA in athletes
Apr 18, 2016

News Scan for Apr 18, 2016

Hospital MERS detection
H7N9 cases in China
Healthcare visits and Ebola
Antimicrobial stewardship
Apr 11, 2016

Avian Flu Scan for Apr 11, 2016

H7N9 cases in China
H5N1 outbreak in Vietnam
Mar 30, 2016

Avian Flu Scan for Mar 30, 2016

H7N9 case in China
More H5N1 in Nigeria
Mar 28, 2016

Avian Flu Scan for Mar 28, 2016

H7N9 case in China
H5N8 outbreak in South Korea
Mar 21, 2016

News Scan for Mar 21, 2016

More Ebola in Guinea
Flu virus in coughs, breaths
H7N9 case in Hong Kong
New anthrax drug approved
Mar 17, 2016

Flu Scan for Mar 17, 2016

Canadian flu vaccine effectiveness
New H7N9 case in China

Resources & Literature


Jump to Recent Literature


Last updated Oct 8, 2014

Center of Excellence for Influenza Research and Surveillance (CEIRS) Resources

H7N9 PDF of epidemiologic curve, other case graphs, and map
PowerPoint slides of the H7N9 graphs and map



Latest Case Information

Frequently updated case list from FluTrackers
Graphs, charts, maps, and other info from FluTrackers
Case table and other info from Flu Wiki
Healthmap.org (search for H7N9 near top)
Disease outbreak news from WHO
Graphs, charts, maps, and other info from Virology Down Under
Google case map compiled by South China Morning Post
H7N9 infographic from Bloomberg News
Genetic analysis of virus from The Lancet (May 1, 2013)

Health Agency Documents

World Health Organization (WHO)

H7N9 page
Risk assessment (Jul 4, 2013)
H7N9 overview (May 31, 2013)
Latest case update (May 29, 2013)
Candidate vaccine viruses (May 26, 2014)
Joint mission report (May 18, 2013)
Lab guidance (May 10, 2013)
Surveillance recommendations (May 10, 2013)
Frequently asked questions (Feb 14, 2014)
Preliminary assessments of age and sex distribution (Apr 22, 2013)
RT-PCR protocol for H7N9 detection (Apr 15, 2013)
Background and summary (Apr 5, 2013)
Weekly report

US Centers for Disease Control and Prevention (CDC)

H7N9 page (updated Feb 12, 2014)
                                                                                                                           Frequently asked questions (Sep 9, 2014)
                                                                                                       Interim guidance on case definitions (Jan 10, 2014)
                                                                                          Study on risk factors (Jun 17, 2014)                                                                                                                    Top 10 pandemic response planning tips (May 30, 2013)
                                                                                   Emergence of avian influenza A(H7N9) virus causing severe human illness (May 10, 2013)                     Interim guidance for healthcare professionals (Jan 23, 2014)                                                                       Interim antiviral guidance (Sep 30, 2013)                                                                                                             Interim guidance on chemoprophylaxis with antiviral medications (Sep 30, 2013)                                 Testing recommendations for possible H7N9 infection in US (Jan 24, 2014)                                               H7N9 images

Department of Health and Human Services (HHS)

H7N9 page

Hong Kong Centre for Health Protection (CHP)
Avian influenza page

Weekly avian influenza report

Chinese Center for Disease Control and Prevention

H7N9 page
Daily updates
Frequently asked questions
Research highlights
Health tips for travelers

European Centre for Disease Prevention and Control (ECDC)

Risk assessment (Jan 27, 2014)
Epidemiologic update (Feb 7, 2014)
Case definition and case finding algorithm (Apr 26, 2013)
Genetic analysis from Euro Surveill (Apr 18, 2013)
Detection and clinical validation guidance from Euro Surveill (Apr 18, 2013)
Avian influenza page                                                                                                                                        Laboratory preparedness in EU/EEA for detection of H7N9 from Euro Surveill (Jan 30, 2014)

Public Health Agency of Canada (PHAC)

H7N9 page 
Travel health notice (Feb 17, 2014)
Public health notice (Oct 8, 2014)
Risk assessment (Oct 8, 2014)
Infection prevention and control guidance (Jun 24, 2013)

Biosafety advisory (Mar 17, 2014)

Public Health England (PHE)

Guidance for possible cases in travelers

World Organization for Animal Health (OIE)

Frequently asked questions
Statement on key role of live-bird markets (Apr 30, 2013)

Food and Agriculture Organization (FAO)

Frequently asked questions (May 27, 2013)

American Public Health Association (APHA)

What you should know now (Apr 19, 2013 blog post)


Helen Branswell (@HelenBranswell)
CDC: Flu (@CDCFlu)
Michael Coston (@Fla_Medic)
Martin Enserink (@martinenserink)
FluTrackers.com (@FluTrackers)
Jason Gale (@jwgale)
GISAID AI Digest (@AIDigest)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
nprGlobalHealth (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)


Recent Literature

Chan EYY, Cheng CKY, Tam G, et al. Knowledge, attitudes, and practices of Hong Kong population towards human A/H7N9 influenza pandemic preparedness, China, 2014. BMC Public Health 2015 Sep 22;15:943

Chen C, Wang M, Zhu Z, et al. Multiple gene mutations identified in patients infected with influenza A (H7N9) virus. Sci Rep 2016 (published online May 9)

Chen H, Liu S, Liu J, et al. Nosocomial co-transmission of avian influenza A(H7N9) and A(H1N1)pdm09 viruses between 2 patients with hematologic disorders. Emerg Infect Dis 2016 (published online Feb 23)

Cheng QL, Ding H, Sun Z, et al. Retrospective study of risk factors of mortality in human avian influenza A(H7N9) cases in Zhejiang Province, China, March 2013 to June 2014. Int J Infect Dis 2015 (published online Sep 13)

FAO. Addressing avian influenza A(H7N9): guidelines for risk communication messaging. Sep 25, 2015

Farooqui A, Liu W, Zeng T, et al. Probable hospital cluster of H7N9 influenza infection. (Letter) N Engl J Med 2016 Feb 11;374:596-98

Jackson LA, Campbell JD, Frey SE, et al. Effect of varying doses of a monovalent H7N9 influenza vaccine with and without AS03 and MF59 adjuvants on immune response: a randomized clinical trial. JAMA 2015 Jul 21;314(3):237-46

He F, Chen EF, Li FD, et al. Human infection and environmental contamination with avian influenza A (H7N9) virus in Zhejiang Province, China: risk trend across the three waves of infection. BMC Public Health 2015 Sep 21;15:931

Hoffmann J, Otte A, Thiele S, et al. Sex differences in H7N9 influenza A virus pathogenesis. Vaccine 2015 (published online Aug 25)

Leung Y, To M, Lam T, et al. Epidemiology of human influenza A(H7N9) infection in Hong Kong. J Microbiol Immunol Infect 2015 (published online Jul 25)

Nakamura K, Shirakura M, Suzuki Y, et al. Development of a high-yield reassortant influenza vaccine virus derived from the A/Anhui/1/2013 (H7N9) strain. Vaccine 2015 (published online Dec 1)

Root JJ, Bosco-Lauth AM, Bielefeldt-Ohmann H, et al. Experimental infection of peridomestic mammals with emergent H7N9 (A/Anhui/1/2013) influenza A virus: implications for biosecurity and wet markets. Virology 2015 (published online Nov 6)

Rudenko L, Isakova-Sivak I, Naykhin A, et al. H7N9 live attenuated influenza vaccine in healthy adults: a randomised, double-blind, placebo-controlled, phase 1 trial. Lancet Infect Dis 2015 (published online Dec 7)

Shi D, Shen S, Gan X, et al. Evaluation of commercial diagnostic assays for the specific detection of avian influenza A(H7N9) virus RNA using a quality-control panel and clinical specimens in China. PLoS One 2015 (published online Sep 11)

Skowronski DM, Chambers C, Gustafson R, et al. Avian influenza A(H7N9) virus infection in 2 travelers returning from China to Canada, January 2015. Emerg Infect Dis 2015 (published online Sep 25)

Sobhanie M, Matsuoka Y, Jegaskanda S, et al. Evaluation of the safety and immunogenicity of a candidate pandemic live attenuated influenza vaccine (pLAIV) against influenza A(H7N9). J Infect Dis 2015 (published online Dec 9)

Virlogeux V, Yang J, Fang VJ, et al. Association between the severity of influenza A(H7N9) virus infections and length of the incubation period. PLoS One 2016 Feb 17;11(2):e0148506

Wang X, Liu S, Mao H, et al. Surveillance of avian H7N9 virus in various environments of Zhejiang Province, China before and after live poultry markets were closed in 2013-2014. PLoS One 2015 Aug 26;10(8):e0135718

Wu P, Peng Z, Fang VJ, et al. Human infection with influenza A(H7N9) virus during 3 major epidemic waves, China, 2013-2015. Emerg Infect Dis 2016 (published online May 12)

Xie S, Jia W, Lin Y, et al. Third wave of influenza A(H7N9) virus from poultry, Guangdong Province, China, 2014-2015. Emerg Infect Dis 2015 (published online Jul 1)

Yuan J, Lau EHY, Li K, et al. Effect of live poultry market closure on avian influenza A(H7N9) virus activity in Guangzhou, China, 2014. Emerg Infect Dis 2015 (published online Sep 3)

Zhang YK, Li J,  Yang JP, et al. Lung ultrasonography for the diagnosis of 11 patients with acute respiratory distress syndrome due to bird flu H7N9 infection. Virol J 2015 (published online Oct 26)

Zhou X, Li Y, Wang Y, et al. The role of live poultry movement and live bird market biosecurity in the epidemiology of influenza A(H7N9): a cross-sectional observational study in four eastern China provinces. J Infect 2015 (published online Jul)

Newsletter Sign-up

Get CIDRAP news.

Sign up now»


Unrestricted financial support provided by

Bentson Foundation 3MGilead Become an underwriter»