H7N9 Avian Influenza

Recent News

Aug 27, 2015

Flu Scan for Aug 27, 2015

H5N1 in Ivory Coast and Nigeria
H7N9 research highlights
Global flu update
Aug 24, 2015

Avian Flu Scan for Aug 24, 2015

H5N1 in Russian birds
H7N9 evolution
Jul 22, 2015

Flu Scan for Jul 22, 2015

H7N9 vaccine and adjuvants
Broadly protective flu vaccine
H5N1 in China, Ghana
Jul 20, 2015

Avian Flu Scan for Jul 20, 2015

West Africa H5N1 alert
More H5N2 in Taiwan
WHO on H7N9 cases in China
Jul 10, 2015

Flu Scan for Jul 10, 2015

H7N9 cases in China
Influenza B lineages compared
Jun 22, 2015

Avian Flu Scan for Jun 22, 2015

Novel H5N9 virus in chickens
H5N1 in China, Israel
Jun 15, 2015

Avian Flu Scan for Jun 15, 2015

H7N9 cases in China
H5N1 in Iranian flock
H5N2 outbreaks in Taiwan
Jun 11, 2015

Avian Flu Scan for Jun 11, 2015

H7N9 cases, death in China
H5N1 in Ghanaian chickens
Jun 10, 2015

News Scan for Jun 10, 2015

Mideast MERS cases
More H7N9 in China
Effect of rotavirus vaccine
Acid suppression and C diff
Vaccine exemptions
Zika virus alert
Jun 09, 2015

News Scan for Jun 09, 2015

Saudi MERS case
XDR-TB traveler in US
H7N9 cases in China

Resources & Literature

Resources

Jump to Recent Literature

 

Last updated Oct 8, 2014

Center of Excellence for Influenza Research and Surveillance (CEIRS) Resources

H7N9 PDF of epidemiologic curve, other case graphs, and map
PowerPoint slides of the H7N9 graphs and map

 

 


Latest Case Information

Frequently updated case list from FluTrackers
Graphs, charts, maps, and other info from FluTrackers
Case table and other info from Flu Wiki
Healthmap.org (search for H7N9 near top)
Disease outbreak news from WHO
Graphs, charts, maps, and other info from Virology Down Under
Google case map compiled by South China Morning Post
H7N9 infographic from Bloomberg News
Genetic analysis of virus from The Lancet (May 1, 2013)

Health Agency Documents

World Health Organization (WHO)

H7N9 page
Risk assessment (Jul 4, 2013)
H7N9 overview (May 31, 2013)
Latest case update (May 29, 2013)
Candidate vaccine viruses (May 26, 2014)
Joint mission report (May 18, 2013)
Lab guidance (May 10, 2013)
Surveillance recommendations (May 10, 2013)
Frequently asked questions (Feb 14, 2014)
Preliminary assessments of age and sex distribution (Apr 22, 2013)
RT-PCR protocol for H7N9 detection (Apr 15, 2013)
Background and summary (Apr 5, 2013)
Weekly report

US Centers for Disease Control and Prevention (CDC)

H7N9 page (updated Feb 12, 2014)
                                                                                                                           Frequently asked questions (Sep 9, 2014)
                                                                                                       Interim guidance on case definitions (Jan 10, 2014)
                                                                                          Study on risk factors (Jun 17, 2014)                                                                                                                    Top 10 pandemic response planning tips (May 30, 2013)
                                                                                   Emergence of avian influenza A(H7N9) virus causing severe human illness (May 10, 2013)                     Interim guidance for healthcare professionals (Jan 23, 2014)                                                                       Interim antiviral guidance (Sep 30, 2013)                                                                                                             Interim guidance on chemoprophylaxis with antiviral medications (Sep 30, 2013)                                 Testing recommendations for possible H7N9 infection in US (Jan 24, 2014)                                               H7N9 images

Department of Health and Human Services (HHS)

H7N9 page

Hong Kong Centre for Health Protection (CHP)
Avian influenza page

Weekly avian influenza report

Chinese Center for Disease Control and Prevention

H7N9 page
Daily updates
Frequently asked questions
Research highlights
Health tips for travelers

European Centre for Disease Prevention and Control (ECDC)

Risk assessment (Jan 27, 2014)
Epidemiologic update (Feb 7, 2014)
Case definition and case finding algorithm (Apr 26, 2013)
Genetic analysis from Euro Surveill (Apr 18, 2013)
Detection and clinical validation guidance from Euro Surveill (Apr 18, 2013)
Avian influenza page                                                                                                                                        Laboratory preparedness in EU/EEA for detection of H7N9 from Euro Surveill (Jan 30, 2014)

Public Health Agency of Canada (PHAC)

H7N9 page 
Travel health notice (Feb 17, 2014)
Public health notice (Oct 8, 2014)
Risk assessment (Oct 8, 2014)
Infection prevention and control guidance (Jun 24, 2013)

Biosafety advisory (Mar 17, 2014)

Public Health England (PHE)

Guidance for possible cases in travelers

World Organization for Animal Health (OIE)

Frequently asked questions
Statement on key role of live-bird markets (Apr 30, 2013)

Food and Agriculture Organization (FAO)

Frequently asked questions (May 27, 2013)

American Public Health Association (APHA)

What you should know now (Apr 19, 2013 blog post)

Twitter

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
CDC: Flu (@CDCFlu)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers.com (@FluTrackers)
Jason Gale (@jwgale)
GISAID AI Digest (@AIDigest)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
nprGlobalHealth (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

 

Recent Literature

Cheng VCC, Tai JWM, Lee WM, et al. Infection control preparedness for human infection with influenza A H7N9 in Hong Kong. Infect Control Hosp Epidemiol 2015 Jan;36(1):87-92

Ding H, Chen Y, Yu Z, et al. A family cluster of three confirmed cases infected with avian influenza A (H7N9) virus in Zhejiang Province of China. BMC Infect Dis 2014 Dec 31;14:3846

Dunand CJH, Leon PE, Kaur K, et al. Preexisting human antibodies neutralize recently emerged H7N9 influenza strains. J Clin Invest 2015 (published online Feb 17)

Farooqui A, Leon AJ, Huang L, et al. Genetic diversity of the 2013-14 human isolates of influenza H7N9 in China. BMC Infect Dis 2015 Feb 28;15:109

Feng L, Wu JT, Liu X, et al. Clinical severity of human infections with avian influenza A(H7N9) virus, China, 2013/14. Euro Surveill 2014 Dec 11;19(49):pii=20984

Jackson LA, Campbell JD, Frey SE, et al. Effect of varying doses of a monovalent H7N9 influenza vaccine with and without AS03 and MF59 adjuvants on immune response: a randomized clinical trial. JAMA 2015 Jul 21;314(3):237-46

Jones JC, Sonnberg S, Webby RJ, et al. Influenza A(H7N9) virus transmission between finches and poultry. Emerg Infect Dis 2015 (published online Mar 11)

Ke C, Lu J, Wu J, et al. Circulation of reassortant influenza A(H7N9) viruses in poultry and humans, Guangdong province, China, 2013. Emerg Infect Dis 2014 (published online Aug 27)

Kucharski AJ, Mills HL, Donnelly CA, et al. Transmission potential of influenza A(H7N9) virus, China, 2013-2014. Emerg Infect Dis 2015 (published online Apr 1)

Leung Y, To M, Lam T, et al. Epidemiology of human influenza A(H7N9) infection in Hong Kong. J Microbiol Immunol Infect 2015 (published online Jul 25)

Ma MJ, Ma GY, Yang XX, et al. Avian influenza A(H7N9) virus antibodies in close contacts of infected persons, China, 2013-2014. Emerg Infect Dis 2014 (published online Dec 23)

Marjuki H, Mishin VP, Chesnokov AP, et al. Characterization of drug-resistant influenza A(H7N9) variants isolated from an oseltamivir-treated patient in Taiwan. J Infect Dis 2015 Jan 15;211(2):249-57

Millman AJ, Havers F, Iuliano AD, et al. Detecting spread of avian influenza A(H7N9) virus beyond China. Emerg Infect Dis 2015 (published online Apr 6)

Pu J, Wang S, Yin Y, et al. Evolution of the H9N2 influenza genotype that facilitated the genesis of the novel H7N9 virus. Proc Natl Acad Sci 2014 (published online Dec 29)

Qin Y, Horby PW, Tsang TK, et al. Differences in the epidemiology of human cases of avian influenza A(H7N9) and A(H5N1) viruses infection. Clin Infect Dis 2015 (published online May 4)

Spackman E, Pantin-Jackwood M, Swayne DE, et al. Impact of route of exposure and challenge dose on the pathogenesis of H7N9 low pathogenicity avian influenza virus in chickens. Virology 2015 Mar;477:72-81

Terajima M, Co MDT, Cruz J, et al. High antibody-dependent cellular cytotoxicity antibody titers to H5N1 and H7N9 avian influenza A viruses in healthy US adults and older children. J Infect Dis 2015 (published online Mar 20)

Wong SS, Kaplan B, Zanin M, et al. Impact of adjuvants on the immunogenicity and efficacy of split-virion H7N9 vaccine in ferrets. J Infect Dis 2015 (published online Feb 23)

Wu J, Zou L, Ni H, et al. Serologic screenings for H7N9 from three sources among high-risk groups in the early stage of H7N9 circulation in Guangdong Province, China. Virol J 2014 Oct 23;11:184

Xie S, Jia W, Lin Y, et al. Third wave of influenza A(H7N9) virus from poultry, Guangdong Province, China, 2014-2015. Emerg Infect Dis 2015 (published online Jul 1)

Yang JR, Kuo CY, Huang HY, et al. Characterization of influenza A (H7N9) viruses isolated from human cases imported into Taiwan. PLoS One 2015 Mar 6;10(3):e0119792

Zaraket H, Baranovich T, Kaplan BS, et al. Mammalian adaptation of influenza A(H7N9) virus is limited by a narrow genetic bottleneck. Nat Commun 2015 Apr 8;6:6553

Zhou X, Li Y, Wang Y, et al. The role of live poultry movement and live bird market biosecurity in the epidemiology of influenza A(H7N9): a cross-sectional observational study in four eastern China provinces. J Infect 2015 (published online Jul)

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