H7N9 Avian Influenza

Recent News

Aug 15, 2017

News Scan for Aug 15, 2017

Saudi MERS case
H7N9 in China
Recurrent C diff treatment
Oropouche fever in Brazil
Hendra virus threat
Plant-based polio vaccine
Aug 04, 2017

Flu Scan for Aug 04, 2017

H1N2v flu case in Ohio
New H7N9 infection in China
Avian flu outbreaks
Jul 21, 2017

News Scan for Jul 21, 2017

H7N9 case in China
Zika birth defects
High-dose flu vaccine in nursing home patients
Jul 14, 2017
China map

China's weekly H7N9 case totals stay in single digits

In other H7N9 developments, China's agriculture ministry this week announced plans to expand poultry vaccination to the whole country.

Jul 07, 2017

News Scan for Jul 07, 2017

Zika birth defects in US
H7N9 in China
Hantavirus cases rise
Meningitis alert for Soliris treatment
Jun 30, 2017
Market chickens

Six more H7N9 avian flu cases reported in China

Cases are down from the 10 reported last week but show ongoing virus circulation in the summer.

Jun 28, 2017

News Scan for Jun 28, 2017

H7N9 illness cluster
Lassa fever in Nigeria
Somalia cholera outbreak
Jail order for egg execs
Hantavirus in Washington
Jun 26, 2017
DNA analysis

Genetic analysis of H7N9 finds adaptations, clade patterns

Current viruses fall into 2 geographically separate clades.

Jun 23, 2017
Broiler Chickens

USDA: Environmental spread, multiple entries likely fueled US H7N9 outbreaks

The virus may have been introduced multiple times, and environmental spread seems to have played a bigger role than did farming.

Jun 23, 2017
Live poultry sales

Ten H7N9 cases confirmed in China as poultry outbreak noted

The 10 cases, 2 of which were fatal, are an increase from 5 reported last week.

Resources & Literature

Resources

Jump to Recent Literature

 

Last updated Oct 8, 2014

Center of Excellence for Influenza Research and Surveillance (CEIRS) Resources

H7N9 PDF of epidemiologic curve, other case graphs, and map
PowerPoint slides of the H7N9 graphs and map

 

 


Latest Case Information

Frequently updated case list from FluTrackers
Graphs, charts, maps, and other info from FluTrackers
Healthmap.org (search for H7N9 near top)
Disease outbreak news from WHO
Graphs, charts, maps, and other info from Virology Down Under
Google case map compiled by South China Morning Post
H7N9 infographic from Bloomberg News
Genetic analysis of virus from The Lancet (May 1, 2013)

Health Agency Documents

World Health Organization (WHO)

H7N9 page
Risk assessment (Jul 4, 2013)
H7N9 overview (May 31, 2013)
Latest case update (May 29, 2013)
Candidate vaccine viruses (May 26, 2014)
Joint mission report (May 18, 2013)
Lab guidance (May 10, 2013)
Surveillance recommendations (May 10, 2013)
Frequently asked questions (Feb 14, 2014)
Preliminary assessments of age and sex distribution (Apr 22, 2013)
RT-PCR protocol for H7N9 detection (Apr 15, 2013)
Background and summary (Apr 5, 2013)
Weekly report

US Centers for Disease Control and Prevention (CDC)

H7N9 page (updated Feb 12, 2014)

Frequently asked questions
 (Sep 9, 2014)
Interim guidance on case definitions (Jan 10, 2014)
Study on risk factors (Jun 17, 2014)
Top 10 pandemic response planning tips (May 30, 2013)

Emergence of avian influenza A(H7N9) virus causing severe human illness (May 10, 2013)
Testing recommendations for possible H7N9 infection in US (Jan 24, 2014)
H7N9 images

Department of Health and Human Services (HHS)

H7N9 page

Hong Kong Centre for Health Protection (CHP)
Avian influenza page

Weekly avian influenza report

Chinese Center for Disease Control and Prevention

H7N9 page
Daily updates
Frequently asked questions
Research highlights
Health tips for travelers

European Centre for Disease Prevention and Control (ECDC)

Risk assessment (Jan 27, 2014)
Epidemiologic update (Feb 7, 2014)
Case definition and case finding algorithm (Apr 26, 2013)
Genetic analysis from Euro Surveill (Apr 18, 2013)
Detection and clinical validation guidance from Euro Surveill (Apr 18, 2013)
Avian influenza page                                                                                                                                        Laboratory preparedness in EU/EEA for detection of H7N9 from Euro Surveill (Jan 30, 2014)

Public Health Agency of Canada (PHAC)

H7N9 page 
Travel health notice (Feb 17, 2014)
Public health notice (Oct 8, 2014)
Risk assessment (Oct 8, 2014)
Infection prevention and control guidance (Jun 24, 2013)
Biosafety advisory (Mar 17, 2014)

Public Health England (PHE)

Guidance for possible cases in travelers

World Organization for Animal Health (OIE)

Frequently asked questions
Statement on key role of live-bird markets (Apr 30, 2013)

Food and Agriculture Organization (FAO)

Frequently asked questions (May 27, 2013)

American Public Health Association (APHA)

What you should know now (Apr 19, 2013 blog post)

Twitter

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
CDC: Flu (@CDCFlu)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers.com (@FluTrackers)
Jason Gale (@jwgale)
GISAID AI Digest (@AIDigest)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
nprGlobalHealth (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

 

Recent Literature

Bahl K, Senn JJ, Yuzhakov O, et al. Preclinical and clinical demonstration of immunogenicity by mRNA vaccines against H10N8 and H7N9 influenza viruses. Mol Ther 2017 (published online Apr 27)

Cui B, Liao Q, Lam WWT, et al. Avian influenza A/H7N9 risk perception information trust and adoption of protective behaviours among poultry farmers in Jiangsu Province, China. BMC Public Health 2017 May 18;17:463

de Vries RP, Peng W, Grant OC, et al. Three mutations switch H7N9 influenza to human-type receptor specificity. PLoS Pathog 2017 Jun 15;13(6):e1006390

Huo X, Chen L, Qi X, et al. Significantly elevated number of human infections with H7N9 virus in Jiangsu in eastern China, October 2016 to January 2017. Euro Surveill 2017 Mar 30;22(13):pii=30496

Iuliano AD, Jang Y, Jones J, et al. Increase in human infections with avian influenza A(H7N9) virus during the fifth epidemic — China, October 2016-February 2017. MMWR 2017 Mar 3;66(Early release)

Kang M, Lau EHY, Guan W, et al. Epidemiology of human infections with highly pathogenic avian influenza A(H7N9) virus in Guangdong, 2016 to 2017. Euro Surveill 2017 Jul 6;22(27):pii=30568

Kiso M, Iwatsuki-Horimoto K, Yamayoshi S, et al. Emergence of oseltamivir-resistant H7N9 influenza viruses in immunosuppressed cynomolgus macaques. J Infect Dis 2017 (published online Jun 21)

Kwok KO, Riley S, Perera RAPM, et al. Relative incidence and individual-level severity of seasonal influenza A H3N2 compared with 2009 pandemic H1N1. BMC Infect Dis 2017 May 11;17:337

Lin X, Zhang D, Wang X, et al. Attitudes of consumers and live-poultry workers to central slaughtering in controlling H7N9: a cross-sectional study. BMC Public Health 2017 May 26;17:517

Liu WJ, Tan S, Zhao M, et al. Cross-immunities against avian influenza H7N9 virus in the healthy population affected by antigenicity-dependent substitutions. J Infect Dis 2016 (published online Oct 12)

Lu J, Raghwani J, Wu J, et al. Molecular evolution, diversity and adaptation of H7N9 influenza A viruses in China. bioRxiv 2017 (published online Jun 25)

Ma W, Huang H, Chen J, et al. Predictors for fatal human infections with avian H7N9 influenza, evidence from 4 epidemic waves in Jiangsu Province, Eastern China, 2013-2016. Influenza Other Respir Viruses 2017 (published online Jul 4)

Madan A, Segall N, Ferguson M, et al. Immunogenicity and safety of an AS03-adjuvanted H7N9 pandemic influenza vaccine in a randomized trial in healthy adults. J Infect Dis 2016 (published online Sep 7)

Wang X, Jiang H, Wu P, et al. Epidemiology of avian influenza A H7N9 virus in human beings across five epidemics in mainland China, 2013-17: an epidemiological study of laboratory-confirmed case series. Lancet Infect Dis 2017 (published online Jun 2)

Wu UI, Hsieh SM, Lee WS, et al. Safety and immunogenicity of an inactivated cell culture-derived H7N9 influenza vaccine in healthy adults: a phase I/II, prospective, randomized, open-label trial. Vaccine 2017 (published online Jun 28)

Xiang N, Bai T, Kang K, et al. Sero-epidemiologic study of influenza A(H7N9) infection among exposed populations, China 2013-2014. Influenza Other Respir Viruses 2016 (published online Oct 20)

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