H7N9 Avian Influenza

Recent News

Mar 16, 2017
Chicken market

Detailing recent H7N9 cases, WHO notes 3 clusters

The agency says there's still no evidence H7N9 has gained capacity for sustained spread.

Mar 10, 2017

News Scan for Mar 10, 2017

More H7N9 cases in China
European H5N8 outbreaks
Lassa fever in Africa
Mar 06, 2017

News Scan for Mar 06, 2017

Zika in Canadian travelers
H7N9 infections in China
New MERS cases
Mar 03, 2017

News Scan for Mar 03, 2017

Zika cases, birth defects
H7N9 spike
Nut butter E coli outbreak
Yellow fever ebbing
Mar 01, 2017
Tamiflu (oseltamivir)

WHO: H7N9 antiviral resistance likely arose after treatment

Officials said the shifts haven't changed the epidemiologic or clinical patterns in people.

Feb 27, 2017
sequencing background

WHO analysis spotlights resistance in H7N9 gene changes

So far there's no sign that H7N9 epidemiology is changing for humans, but for poultry, the virus has become more deadly.

Feb 23, 2017
China Premiere Li Keqiang

H7N9 surge in China prompts high-level call for market closures

China's premier urges officials in affected areas to shutter live-poultry markets.

Feb 21, 2017
Poultry on a bike trailer

China confirms high-path H7N9 in market poultry

For the first time in China, the high-path strain of H7N9 has been detected in live market poultry.

Feb 21, 2017

News Scan for Feb 21, 2017

H7N9 cases in China
Poultry worker avian flu exposure
Yemen polio campaign
Multi-disease mosquito vaccine
Feb 20, 2017
DNA test

H7N9 analyses hint at genetic mutations, drug resistance

Analyses of samples from China and Taiwan hint at resistance to antiviral drugs.

Resources & Literature

Resources

Jump to Recent Literature

 

Last updated Oct 8, 2014

Center of Excellence for Influenza Research and Surveillance (CEIRS) Resources

H7N9 PDF of epidemiologic curve, other case graphs, and map
PowerPoint slides of the H7N9 graphs and map

 

 


Latest Case Information

Frequently updated case list from FluTrackers
Graphs, charts, maps, and other info from FluTrackers
Case table and other info from Flu Wiki
Healthmap.org (search for H7N9 near top)
Disease outbreak news from WHO
Graphs, charts, maps, and other info from Virology Down Under
Google case map compiled by South China Morning Post
H7N9 infographic from Bloomberg News
Genetic analysis of virus from The Lancet (May 1, 2013)

Health Agency Documents

World Health Organization (WHO)

H7N9 page
Risk assessment (Jul 4, 2013)
H7N9 overview (May 31, 2013)
Latest case update (May 29, 2013)
Candidate vaccine viruses (May 26, 2014)
Joint mission report (May 18, 2013)
Lab guidance (May 10, 2013)
Surveillance recommendations (May 10, 2013)
Frequently asked questions (Feb 14, 2014)
Preliminary assessments of age and sex distribution (Apr 22, 2013)
RT-PCR protocol for H7N9 detection (Apr 15, 2013)
Background and summary (Apr 5, 2013)
Weekly report

US Centers for Disease Control and Prevention (CDC)

H7N9 page (updated Feb 12, 2014)
                                                                                                                           Frequently asked questions (Sep 9, 2014)
                                                                                                       Interim guidance on case definitions (Jan 10, 2014)
                                                                                          Study on risk factors (Jun 17, 2014)                                                                                                                    Top 10 pandemic response planning tips (May 30, 2013)
                                                                                   Emergence of avian influenza A(H7N9) virus causing severe human illness (May 10, 2013)                     Interim guidance for healthcare professionals (Jan 23, 2014)                                                                       Interim antiviral guidance (Sep 30, 2013)                                                                                                             Interim guidance on chemoprophylaxis with antiviral medications (Sep 30, 2013)                                 Testing recommendations for possible H7N9 infection in US (Jan 24, 2014)                                               H7N9 images

Department of Health and Human Services (HHS)

H7N9 page

Hong Kong Centre for Health Protection (CHP)
Avian influenza page

Weekly avian influenza report

Chinese Center for Disease Control and Prevention

H7N9 page
Daily updates
Frequently asked questions
Research highlights
Health tips for travelers

European Centre for Disease Prevention and Control (ECDC)

Risk assessment (Jan 27, 2014)
Epidemiologic update (Feb 7, 2014)
Case definition and case finding algorithm (Apr 26, 2013)
Genetic analysis from Euro Surveill (Apr 18, 2013)
Detection and clinical validation guidance from Euro Surveill (Apr 18, 2013)
Avian influenza page                                                                                                                                        Laboratory preparedness in EU/EEA for detection of H7N9 from Euro Surveill (Jan 30, 2014)

Public Health Agency of Canada (PHAC)

H7N9 page 
Travel health notice (Feb 17, 2014)
Public health notice (Oct 8, 2014)
Risk assessment (Oct 8, 2014)
Infection prevention and control guidance (Jun 24, 2013)

Biosafety advisory (Mar 17, 2014)

Public Health England (PHE)

Guidance for possible cases in travelers

World Organization for Animal Health (OIE)

Frequently asked questions
Statement on key role of live-bird markets (Apr 30, 2013)

Food and Agriculture Organization (FAO)

Frequently asked questions (May 27, 2013)

American Public Health Association (APHA)

What you should know now (Apr 19, 2013 blog post)

Twitter

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
CDC: Flu (@CDCFlu)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers.com (@FluTrackers)
Jason Gale (@jwgale)
GISAID AI Digest (@AIDigest)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
nprGlobalHealth (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

 

Recent Literature

Chen C, Wang M, Zhu Z, et al. Multiple gene mutations identified in patients infected with influenza A (H7N9) virus. Sci Rep 2016 (published online May 9)

Dunand CJH, Leon PE, Huang M, et al. Both neutralizing and non-neutralizing human H7N9 influenza vaccine-induced monoclonal antibodies confer protection. Cell Host Microb 2016 Jun 8;19(6):800-13

Iuliano AD, Jang Y, Jones J, et al. Increase in human infections with avian influenza A(H7N9) virus during the fifth epidemic — China, October 2016-February 2017. MMWR 2017 Mar 3;66(Early release)

Liu WJ, Tan S, Zhao M, et al. Cross-immunities against avian influenza H7N9 virus in the healthy population affected by antigenicity-dependent substitutions. J Infect Dis 2016 (published online Oct 12)

Madan A, Segall N, Ferguson M, et al. Immunogenicity and safety of an AS03-adjuvanted H7N9 pandemic influenza vaccine in a randomized trial in healthy adults. J Infect Dis 2016 (published online Sep 7)

Wu P, Peng Z, Fang VJ, et al. Human infection with influenza A(H7N9) virus during 3 major epidemic waves, China, 2013-2015. Emerg Infect Dis 2016 (published online May 12)

Wu Z, Sha J, Yu Z, et al. Epidemiological and virological differences in human-clustered and sporadic infections with avian influenza A H7N9. Int J Infect Dis 2016 (published online May 24)

Xiang N, Bai T, Kang K, et al. Sero-epidemiologic study of influenza A(H7N9) infection among exposed populations, China 2013-2014. Influenza Other Respir Viruses 2016 (published online Oct 20)

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