H7N9 Avian Influenza

Last Updated
Oct 02, 2013

Recent News

Oct 15, 2013

Chinese man hospitalized with severe H7N9 flu

A man from Zhejiang province is in critical condition with H7N9 flu, the first case in 2 months.

Oct 15, 2013

Flu Scan for Oct 15, 2013

H5N1 in Vietnam
Mercury in flu vaccines
H7N9 vaccine trial
Oct 14, 2013

Flu Scan for Oct 14, 2013

Global flu activity
H7N9 vaccine in Taiwan
Oct 09, 2013

Flu Scan for Oct 09, 2013

H7N9 growth in lung tissue
Low H1N1 vaccine hypersensitivity
Oct 02, 2013

Flu Scan for Oct 02, 2013

H7N9 transmission estimates
H7N9 treatment, prophylaxis guidance
Oct 01, 2013

Fed shutdown affects disease detection, food safety

Response to seasonal flu, H7N9, MERS, and other threats could be markedly diminished.

Sep 27, 2013

News Scan for Sep 27, 2013

H7N9 vaccine strain selection
Vaccine research funding
Tdap vaccine shortage
Sep 26, 2013

Dutch court affirms limit on publishing H5N1 findings

The court upheld an export rule, but virologist Fouchier said the decision won't apply to H7N9 research.

Sep 19, 2013

Avian Flu Scan for Sep 19, 2013

Cambodian H5N1 cases
H7N9 evolution clues
Sep 18, 2013

NIH to test H7N9 vaccines with adjuvants

Clinical trials will test a candidate vaccine for H7N9 flu in varying doses, some with immune boosters.

Resources & Literature

Resources

Jump to Recent Literature

Minnesota Center of Excellence for Influenza Research and Surveillance (MCEIRS) Resources

H7N9 Epi Curve

 

H7N9 PDF of epidemiologic curve, other case graphs, and map
PowerPoint slides of the H7N9 graphs and map

 


Latest Case Information

Frequently updated case list from FluTrackers
Graphs, charts, maps, and other info from FluTrackers
Case table and other info from Flu Wiki
Healthmap.org (search for H7N9 near top)
Disease outbreak news from WHO
Graphs, charts, maps, and other info from Virology Down Under
Google case map compiled by South China Morning Post
H7N9 infographic from Bloomberg News
Genetic analysis of virus from The Lancet (May 1)

Health Agency Documents

World Health Organization (WHO)

H7N9 page
Risk assessment (Jul 4)
H7N9 overview (May 31)
Latest case update (May 29)
Candidate vaccine viruses (May 25)
Joint mission report (May 18)
Lab guidance (May 10)
Surveillance recommendations (May 10)
Frequently asked questions (Apr 30)
Preliminary assessments of age and sex distribution (Apr 22)
RT-PCR protocol for H7N9 detection (Apr 15)
Background and summary (Apr 5)
Weekly report

US Centers for Disease Control and Prevention (CDC)

H7N9 page
Frequently asked questions (Aug 9)
Interim guidance on case definitions (Jun 7)
Top 10 pandemic response planning tips (May 30)
Emergence of avian influenza A(H7N9) virus causing severe human illness (May 10)
Information for travelers to China (Apr 29)
Interim guidance for healthcare professionals (Apr 22)
Interim antiviral guidance (Sep 30)                                                                                       Interim guidance on chemoprophylaxis with antiviral medications (Sep 30)
H7N9 images

Department of Health and Human Services (HHS)

H7N9 page

Hong Kong Centre for Health Protection (CHP)
Avian influenza page

Special notes for the hotel industry
Weekly avian influenza report

Chinese Center for Disease Control and Prevention

H7N9 page
Daily updates
Frequently asked questions
Research highlights
Health tips for travelers

European Centre for Disease Prevention and Control (ECDC)

Risk assessment (May 8)
Epidemiologic update (Apr 29)
Case definition and case finding algorithm (Apr 26)
Genetic analysis from Euro Surveill (Apr 18)
Detection and clinical validation guidance from Euro Surveill (Apr 18)
Avian influenza page

Public Health Agency of Canada (PHAC)

H7N9 page 
Travel health notice (Aug 16)
Public health notice (Jul 27)
Risk assessment (Jul 27)
Infection prevention and control guidance (Jun 24)

Biosafety advisory (Apr 10)

Public Health England (PHE)

Guidance for possible cases in travelers

World Organization for Animal Health (OIE)

Frequently asked questions
Statement on key role of live-bird markets (Apr 30)

Food and Agriculture Organization (FAO)

Frequently asked questions (May 27)
Reducing H7N9 risk with good biosecurity and hygiene (Apr 11)

American Public Health Association (APHA)

What you should know now (Apr 19 blog post)

Twitter

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
CDC: Flu (@CDCFlu)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers.com (@FluTrackers)
Jason Gale (@jwgale)
GISAID AI Digest (@AIDigest)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
nprGlobalHealth (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

Recent Literature

 Yang H, Carney PJ, Chang JC, et al. Structural analysis of the hemagglutinin from the recent 2013 H7N9 influenza virus. J Virol 2013 (published online Sep 11)

Ai J, Huang Y, Xu K, et al. Case-control study of risk factors for human infection with influenza A(H7N9) virus in Jiangsu Province, China, 2013. Euro Surveill 2013 Jun 27;18(26):pii=20510

Baas C, Barr IG, Fouchier RA, et al. A comparison of rapid point-of-care tests for the detection of avian influenza A(H7N9) virus, 2013. Euro Surveill 2013 May 23;18(21):pii=20487

Bai T, Zhou J, Shu Y, et al. Serologic study for influenza A (H7N9) among high-risk groups in China. (Letter) N Engl J Med 2013 Jun 13;368:2339-40

Bao CJ, CUI LB, Zhou MH, et al. Live-animal markets and influenza A (H7N9) virus infection. (Letter) N Engl J Med 2013 Jun 13;368:2337-9

Belser JA, Gustin KM, Pearce MB, et al. Pathogenesis and transmission of avian influenza A (H7N9) virus in ferrets and mice. (Letter) Nature 2013 (published online Jul 10)

Boni MF, Chau NVV, Dong N, et al. Population-level antibody estimates to novel influenza A/H7N9. J Infect Dis 2013 Aug 15;208(4):554-8

CDC. Emergence of avian influenza A(H7N9) virus causing severe human illness--China, February-April 2013. MMWR 2013 May 10;62(18):366-71

CDC. Interim guidance for infection control within healthcare settings when caring for patients with confirmed, probable, or cases under investigation of avian influenza A(H7N9) virus infection. Apr 11, 2013

Chan MCW, Chan RWY, Chan LLY, et al. Tropism and innate host responses of a novel avian influenza A H7N9 virus: an analysis of ex-vivo and in-vitro cultures of the human respiratory tract. Lancet Respi Med 2013 (published online Jul 25)

Chang SY, Lin PH, Tsai JC, et al. The first case of H7N9 influenza in Taiwan. (Letter) Lancet 2013 May 11;381(9878):1621

Chen Y, Liang W, Yang S, et al. Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterization of viral genome. Lancet 2013 Jun 1;381(9881):1916-25

Chi U, Zhu U, Wen T, et al. Cytokine and chemokine levels in patients infected with the novel avian influenza A (H7N9) virus in China. J Infect Dis 2013 (published online Aug 29)

Chowell G, Simonsen L, Towers S, et al. Transmission potential of influenza A/H7N9, February to May 2013, China. BMC Medicine 2013 (published online Oct 2)

Corman VM, Erickmann M, Landt O, et al. Specific detection by real-time reverse-transcription reaction assays of a novel avian influenza A(H7N9) strain associated with human spillover infections in China. Euro Surveill 2013 Apr 18;18(16):pii=20461

Cowling BJ, Freeman G, Wong JY, et al. Preliminary inferences on the age-specific seriousness of human disease caused by avian influenza A(H7N9) infections in China, March to April 2013. Euro Surveill 2013 May 9;18(18):20475

-Cowling BJ, Jin L, Lau EHY, et al. Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases. Lancet 2013 Jul 13;382(9887):129-37

Fang LQ, Li XL, Liu K, et al. Mapping spread and risk of avian influenza A (H7N9) in China. Sci Rep 2013 (published online Sep 26) 

FAO. Addressing the avian influenza A(H7N9) emergency: risk management along the food chain. May 16, 2013

Fouchier RAM, Kawaoka Y, Cardona C, et al. Gain of function experiments on H7N9. (Letter) Nature 2013 Aug 8;500:150-1 

Gao HN, Lu HZ, Cao B, et al. Clinical findings in 111 cases of influenza A (H7N9) virus infection. N Engl J Med 2013 Jun 13;368:2277-85

Gao R, Cao B, Hu Y, et al. Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med 2013 May 16;368:1888-97

Goodwin R, Sun S. Public perceptions and reactions to H7N9 in Mainland China. J Infect 2013 (published online Jul 5)

Hackett H, Bialasiewicz S, Jacob K, et al. Screening for H7N9 influenza A by matrix gene-based real-time reverse-transcription PCR. J Virol Methods 2013 (published online Oct 14)

Han J, Jin M, Zhang P, et al. Epidemiological link between exposure to poultry and all influenza A(H7N9) confirmed cases in Huzhou city, China, March to May 2013. Euro Surveill 2013 May 16;18(20):pii=20481

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