H7N9 Avian Influenza

Recent News

Apr 18, 2014

News Scan for Apr 18, 2014

Flu uptick in Northeast
Two new H7N9 cases
Wikipedia ILI predictions
Guinea Ebola toll
Apr 16, 2014

News Scan for Apr 16, 2014

Chikungunya in Tonga
HPV and throat cancer
New H7N9 case
Apr 15, 2014

Flu Scan for Apr 15, 2014

New H7N9 case in China
Unreported flulike illness
Apr 14, 2014

Flu Scan for Apr 14, 2014

H7N9 update
H5 outbreaks in Japan
Apr 11, 2014

Flu Scan for Apr 11, 2014

New H7N9 case in China
US flu activity stays level
Flu centers of excellence
Apr 10, 2014

China, Hong Kong report four more H7N9 cases

The new H7N9 cases include three from the mainland and one from Hong Kong.

Apr 10, 2014

News Scan for Apr 10, 2014

Flu antiviral efficacy
Experimental H7N9 vaccine
Zika in blood donors
Apr 09, 2014

Avian Flu Scan for Apr 09, 2014

New H7N9 case
H5N1 in North Korea
Apr 07, 2014

Flu Scan for Apr 07, 2014

Two new H7N9 cases
H5N1 case in Egypt
Low global flu activity
Apr 04, 2014

Flu Scan for Apr 04, 2014

Uptick in flu activity
More H7N9 cases

Resources & Literature


Jump to Recent Literature


Last updated Apr 14, 2014

Center of Excellence for Influenza Research and Surveillance (CEIRS) Resources

H7N9 PDF of epidemiologic curve, other case graphs, and map
PowerPoint slides of the H7N9 graphs and map



Latest Case Information

Frequently updated case list from FluTrackers
Graphs, charts, maps, and other info from FluTrackers
Case table and other info from Flu Wiki
Healthmap.org (search for H7N9 near top)
Disease outbreak news from WHO
Graphs, charts, maps, and other info from Virology Down Under
Google case map compiled by South China Morning Post
H7N9 infographic from Bloomberg News
Genetic analysis of virus from The Lancet (May 1, 2013)

Health Agency Documents

World Health Organization (WHO)

H7N9 page
Risk assessment (Jul 4, 2013)
H7N9 overview (May 31, 2013)
Latest case update (May 29, 2013)
Candidate vaccine viruses (Jan 24, 2014)
Joint mission report (May 18, 2013)
Lab guidance (May 10, 2013)
Surveillance recommendations (May 10, 2013)
Frequently asked questions (Apr 30, 2013)
Preliminary assessments of age and sex distribution (Apr 22, 2013)
RT-PCR protocol for H7N9 detection (Apr 15, 2013)
Background and summary (Apr 5, 2013)
Weekly report

US Centers for Disease Control and Prevention (CDC)

US Centers for Disease Control and Prevention (CDC)

H7N9 page (updated Jan 17, 2014)
                                                                                                                           Frequently asked questions (Aug 30, 2013)
                                                                                                       Interim guidance on case definitions (Jan 10, 2014)
                                                                                           Top 10 pandemic response planning tips (May 30, 2013)
                                                                                   Emergence of avian influenza A(H7N9) virus causing severe human illness (May 10, 2013)                     Information for travelers to China (updated Jan 22, 2014)
                                                                               Interim guidance for healthcare professionals (Jan 23, 2014)                                                                       Interim antiviral guidance (Sep 30, 2013)                                                                                                             Interim guidance on chemoprophylaxis with antiviral medications (Sep 30, 2013)                                 Testing recommendations for possible H7N9 infection in US (Jan 24, 2014)                                               H7N9 images

Department of Health and Human Services (HHS)

H7N9 page

Hong Kong Centre for Health Protection (CHP)
Avian influenza page

Special notes for the hotel industry
Weekly avian influenza report

Chinese Center for Disease Control and Prevention

H7N9 page
Daily updates
Frequently asked questions
Research highlights
Health tips for travelers

European Centre for Disease Prevention and Control (ECDC)

Risk assessment (Jan 27, 2014)
Epidemiologic update (Apr 29, 2013)
Case definition and case finding algorithm (Apr 26, 2013)
Genetic analysis from Euro Surveill (Apr 18, 2013)
Detection and clinical validation guidance from Euro Surveill (Apr 18, 2013)
Avian influenza page                                                                                                                                        Laboratory preparedness in EU/EEA for detection of H7N9 from Euro Surveill (Jan 30, 2014)

Public Health Agency of Canada (PHAC)

H7N9 page 
Travel health notice (Dec 20, 2013)
Public health notice (Jan 29, 2014)
Risk assessment (Jul 29, 2014)
Infection prevention and control guidance (Jun 24, 2013)

Biosafety advisory (Apr 10, 2013)

Public Health England (PHE)

Guidance for possible cases in travelers

World Organization for Animal Health (OIE)

Frequently asked questions
Statement on key role of live-bird markets (Apr 30, 2013)

Food and Agriculture Organization (FAO)

Frequently asked questions (May 27, 2013)
Reducing H7N9 risk with good biosecurity and hygiene (Apr 11, 2013)

American Public Health Association (APHA)

What you should know now (Apr 19, 2013 blog post)


Helen Branswell (@HelenBranswell)
CDC: Flu (@CDCFlu)
Michael Coston (@Fla_Medic)
Martin Enserink (@martinenserink)
FluTrackers.com (@FluTrackers)
Jason Gale (@jwgale)
GISAID AI Digest (@AIDigest)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
nprGlobalHealth (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

H7N9 PDF of epidemiologic curve, other case graphs, and map
PowerPoint slides of the H7N9 graphs and map

Recent Literature

Ai J, Huang Y, Xu K, et al. Case-control study of risk factors for human infection with influenza A(H7N9) virus in Jiangsu Province, China, 2013. Euro Surveill 2013 Jun 27;18(26):pii=20510

Baas C, Barr IG, Fouchier RA, et al. A comparison of rapid point-of-care tests for the detection of avian influenza A(H7N9) virus, 2013. Euro Surveill 2013 May 23;18(21):pii=20487

Bai T, Zhou J, Shu Y, et al. Serologic study for influenza A (H7N9) among high-risk groups in China. (Letter) N Engl J Med 2013 Jun 13;368:2339-40

Bao CJ, CUI LB, Zhou MH, et al. Live-animal markets and influenza A (H7N9) virus infection. (Letter) N Engl J Med 2013 Jun 13;368:2337-9

Belser JA, Gustin KM, Pearce MB, et al. Pathogenesis and transmission of avian influenza A (H7N9) virus in ferrets and mice. (Letter) Nature 2013 (published online Jul 10)

Boni MF, Chau NVV, Dong N, et al. Population-level antibody estimates to novel influenza A/H7N9. J Infect Dis 2013 Aug 15;208(4):554-8

CDC. Emergence of avian influenza A(H7N9) virus causing severe human illness--China, February-April 2013. MMWR 2013 May 10;62(18):366-71

Chan MCW, Chan RWY, Chan LLY, et al. Tropism and innate host responses of a novel avian influenza A H7N9 virus: an analysis of ex-vivo and in-vitro cultures of the human respiratory tract. Lancet Respi Med 2013 (published online Jul 25)

Chang SY, Lin PH, Tsai JC, et al. The first case of H7N9 influenza in Taiwan. (Letter) Lancet 2013 May 11;381(9878):1621

Chen Y, Liang W, Yang S, et al. Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterization of viral genome. Lancet 2013 Jun 1;381(9881):1916-25

Chen Z, Baz M, Lu J, et al. Development of a high yield live attenuated H7N9 influenza vaccine that provides protection against homologous and heterologous H7 wild-type viruses in ferrets. J Virol 2014 (published online Apr 9)

Chi U, Zhu U, Wen T, et al. Cytokine and chemokine levels in patients infected with the novel avian influenza A (H7N9) virus in China. J Infect Dis 2013 (published online Aug 29)

Chowell G, Simonsen L, Towers S, et al. Transmission potential of influenza A/H7N9, February to May 2013, China. BMC Medicine 2013 (published online Oct 2)

Cowling BJ, Freeman G, Wong JY, et al. Preliminary inferences on the age-specific seriousness of human disease caused by avian influenza A(H7N9) infections in China, March to April 2013. Euro Surveill 2013 May 9;18(18):20475

Cowling BJ, Jin L, Lau EHY, et al. Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases. Lancet 2013 Jul 13;382(9887):129-37

Ding H, Xie L, Sun Z, et al. Epidemiologic characterization of 30 confirmed cases of human infection with avian influenza A(H7N9) virus in Hangzhou, China. BMC Infect Dis 2014 Mar 31;14:175

Fang LQ, Li XL, Liu K, et al. Mapping spread and risk of avian influenza A (H7N9) in China. Sci Rep 2013 (published online Sep 26) 

FAO. Addressing the avian influenza A(H7N9) emergency: risk management along the food chain. May 16, 2013

Feng Y, Mao H, Xu C, et al. Origin and characteristics of internal genes affect infectivity of the novel avian-origin influenza A (H7N9) virus. PLoS One 2013 (published online Nov 22)

Fouchier RAM, Kawaoka Y, Cardona C, et al. Gain of function experiments on H7N9. (Letter) Nature 2013 Aug 8;500:150-1 

Fuller T, Havers F, Xu C, et al. Identifying areas with a high risk of human infection with the avian influenza A (H7N9) virus in East Asia. J Infect 2014 (published online Mar 15)

Gabbard JD, Dlugolenski D, Van Riel D, et al. Novel H7N9 influenza virus shows low infectious dose, high growth and efficient contact transmission in the guinea pig model. J Virol 2013 (published online Nov 13) 

Gao HN, Lu HZ, Cao B, et al. Clinical findings in 111 cases of influenza A (H7N9) virus infection. N Engl J Med 2013 Jun 13;368:2277-85

Goodwin R, Sun S. Public perceptions and reactions to H7N9 in Mainland China. J Infect 2013 (published online Jul 5)

Hackett H, Bialasiewicz S, Jacob K, et al. Screening for H7N9 influenza A by matrix gene-based real-time reverse-transcription PCR. J Virol Methods 2013 (published online Oct 14)

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