H7N9 Avian Influenza

Recent News

Oct 19, 2017
Ferret

Study: latest H7N9 strains edge closer to efficient transmission

In a sample from a patient who died, researchers saw signs that the H7N9 virus had started to mutate to a form resistant to Tamiflu.

Sep 25, 2017

Flu Scan for Sep 25, 2017

Flu in Maryland fair pigs
H7N9 cluster analysis
Peramivir pediatric indication
H5N1 in Malaysia
Sep 19, 2017

News Scan for Sep 19, 2017

H7N9 vaccine development
Cyclospora cases rise
MERS vaccine trial
Zika transmission prediction
Nigerian cholera vaccination
Sep 08, 2017

Flu Scan for Sep 08, 2017

Flu vaccine not tied to embolism
H7N9 case in China
H5N8 outbreak in Africa
Sep 07, 2017

Avian Flu Scan for Sep 07, 2017

Lab-created H5N8-H5N1 virus
H7N9 fifth-wave features
Bird outbreaks in Taiwan, Italy
Sep 01, 2017

Flu Scan for Sep 01, 2017

H1N2v case in Ohio
H7N9 death in China
Canine influenza
Aug 25, 2017

Flu Scan for Aug 25, 2017

H7N9 cases in China
Philippines H5N6 monitoring
Impact of no nasal flu vaccine
Aug 15, 2017

News Scan for Aug 15, 2017

Saudi MERS case
H7N9 in China
Recurrent C diff treatment
Oropouche fever in Brazil
Hendra virus threat
Plant-based polio vaccine
Aug 04, 2017

Flu Scan for Aug 04, 2017

H1N2v flu case in Ohio
New H7N9 infection in China
Avian flu outbreaks
Jul 21, 2017

News Scan for Jul 21, 2017

H7N9 case in China
Zika birth defects
High-dose flu vaccine in nursing home patients

Resources & Literature

Resources

Jump to Recent Literature

 

Last updated Oct 8, 2014

Center of Excellence for Influenza Research and Surveillance (CEIRS) Resources

H7N9 PDF of epidemiologic curve, other case graphs, and map
PowerPoint slides of the H7N9 graphs and map

 

 


Latest Case Information

Frequently updated case list from FluTrackers
Graphs, charts, maps, and other info from FluTrackers
Healthmap.org (search for H7N9 near top)
Disease outbreak news from WHO
Graphs, charts, maps, and other info from Virology Down Under
Google case map compiled by South China Morning Post
H7N9 infographic from Bloomberg News
Genetic analysis of virus from The Lancet (May 1, 2013)

Health Agency Documents

World Health Organization (WHO)

H7N9 page
Risk assessment (Jul 4, 2013)
H7N9 overview (May 31, 2013)
Latest case update (May 29, 2013)
Candidate vaccine viruses (May 26, 2014)
Joint mission report (May 18, 2013)
Lab guidance (May 10, 2013)
Surveillance recommendations (May 10, 2013)
Frequently asked questions (Feb 14, 2014)
Preliminary assessments of age and sex distribution (Apr 22, 2013)
RT-PCR protocol for H7N9 detection (Apr 15, 2013)
Background and summary (Apr 5, 2013)
Weekly report

US Centers for Disease Control and Prevention (CDC)

H7N9 page (updated Feb 12, 2014)

Frequently asked questions
 (Sep 9, 2014)
Interim guidance on case definitions (Jan 10, 2014)
Study on risk factors (Jun 17, 2014)
Top 10 pandemic response planning tips (May 30, 2013)

Emergence of avian influenza A(H7N9) virus causing severe human illness (May 10, 2013)
Testing recommendations for possible H7N9 infection in US (Jan 24, 2014)
H7N9 images

Department of Health and Human Services (HHS)

H7N9 page

Hong Kong Centre for Health Protection (CHP)
Avian influenza page

Weekly avian influenza report

Chinese Center for Disease Control and Prevention

H7N9 page
Daily updates
Frequently asked questions
Research highlights
Health tips for travelers

European Centre for Disease Prevention and Control (ECDC)

Risk assessment (Jan 27, 2014)
Epidemiologic update (Feb 7, 2014)
Case definition and case finding algorithm (Apr 26, 2013)
Genetic analysis from Euro Surveill (Apr 18, 2013)
Detection and clinical validation guidance from Euro Surveill (Apr 18, 2013)
Avian influenza page                                                                                                                                        Laboratory preparedness in EU/EEA for detection of H7N9 from Euro Surveill (Jan 30, 2014)

Public Health Agency of Canada (PHAC)

H7N9 page 
Travel health notice (Feb 17, 2014)
Public health notice (Oct 8, 2014)
Risk assessment (Oct 8, 2014)
Infection prevention and control guidance (Jun 24, 2013)
Biosafety advisory (Mar 17, 2014)

Public Health England (PHE)

Guidance for possible cases in travelers

World Organization for Animal Health (OIE)

Frequently asked questions
Statement on key role of live-bird markets (Apr 30, 2013)

Food and Agriculture Organization (FAO)

Frequently asked questions (May 27, 2013)

American Public Health Association (APHA)

What you should know now (Apr 19, 2013 blog post)

Twitter

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
CDC: Flu (@CDCFlu)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers.com (@FluTrackers)
Jason Gale (@jwgale)
GISAID AI Digest (@AIDigest)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
nprGlobalHealth (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

 

Recent Literature

Bahl K, Senn JJ, Yuzhakov O, et al. Preclinical and clinical demonstration of immunogenicity by mRNA vaccines against H10N8 and H7N9 influenza viruses. Mol Ther 2017 (published online Apr 27)

Cui B, Liao Q, Lam WWT, et al. Avian influenza A/H7N9 risk perception information trust and adoption of protective behaviours among poultry farmers in Jiangsu Province, China. BMC Public Health 2017 May 18;17:463

de Vries RP, Peng W, Grant OC, et al. Three mutations switch H7N9 influenza to human-type receptor specificity. PLoS Pathog 2017 Jun 15;13(6):e1006390

Huang DTN, Lu CY, Chi YH, et al. Adaptation of influenza A(H7N9) virus in primary human airway epithelial cells. Sci Rep 2017 (published online Sep 12)

Huo X, Chen L, Qi X, et al. Significantly elevated number of human infections with H7N9 virus in Jiangsu in eastern China, October 2016 to January 2017. Euro Surveill 2017 Mar 30;22(13):pii=30496

Iuliano AD, Jang Y, Jones J, et al. Increase in human infections with avian influenza A(H7N9) virus during the fifth epidemic — China, October 2016-February 2017. MMWR 2017 Mar 3;66(Early release)

Kang M, Lau EHY, Guan W, et al. Epidemiology of human infections with highly pathogenic avian influenza A(H7N9) virus in Guangdong, 2016 to 2017. Euro Surveill 2017 Jul 6;22(27):pii=30568

Kile JC, Ren R, Liu L, et al. Increase in human infections with novel Asian lineage avian influenza A(H7N9) viruses during the fifth epidemic — China, October 1, 2016-August 7, 2017. (Update) MMWR 2017 Sep 8;66(35):928-32

Kiso M, Iwatsuki-Horimoto K, Yamayoshi S, et al. Emergence of oseltamivir-resistant H7N9 influenza viruses in immunosuppressed cynomolgus macaques. J Infect Dis 2017 (published online Jun 21)

Kwok KO, Riley S, Perera RAPM, et al. Relative incidence and individual-level severity of seasonal influenza A H3N2 compared with 2009 pandemic H1N1. BMC Infect Dis 2017 May 11;17:337

Lin X, Zhang D, Wang X, et al. Attitudes of consumers and live-poultry workers to central slaughtering in controlling H7N9: a cross-sectional study. BMC Public Health 2017 May 26;17:517

Liu B, Havers FP, Zhou L, et al. Clusters of human infections with avian influenza A(H7N9) virus in China, March 2013 to June 2015. J Infect Dis 2017 (published online Sep 19)

Liu D, Zhang Z, He L, et al. Characteristics of the emerging chicken-origin highly pathogenic H7N9 viruses: a new threat to public health and poultry industry. J Infect 2017 (published online Sep 20)

Lu J, Raghwani J, Wu J, et al. Molecular evolution, diversity and adaptation of H7N9 influenza A viruses in China. bioRxiv 2017 (published online Jun 25)

Ma W, Huang H, Chen J, et al. Predictors for fatal human infections with avian H7N9 influenza, evidence from 4 epidemic waves in Jiangsu Province, Eastern China, 2013-2016. Influenza Other Respir Viruses 2017 (published online Jul 4)

Wang X, Jiang H, Wu P, et al. Epidemiology of avian influenza A H7N9 virus in human beings across five epidemics in mainland China, 2013-17: an epidemiological study of laboratory-confirmed case series. Lancet Infect Dis 2017 (published online Jun 2)

Wu UI, Hsieh SM, Lee WS, et al. Safety and immunogenicity of an inactivated cell culture-derived H7N9 influenza vaccine in healthy adults: a phase I/II, prospective, randomized, open-label trial. Vaccine 2017 (published online Jun 28)

Xiang N, Bai T, Kang K, et al. Sero-epidemiologic study of influenza A(H7N9) infection among exposed populations, China 2013-2014. Influenza Other Respir Viruses 2016 (published online Oct 20)

Yang L, Zhu W, Li X, et al. Genesis and spread of newly emerged highly pathogenic H7N9 avian viruses in mainland China. J Virol 2017 (published online Sep 27)

Yu F, Song H, Wu Y, et al. A potent germline-like human monoclonal antibody targets a pH-sensitive epitope on H7N9 influenza hemagglutinin. Cell Host Microbe 2017 (published online Sep 28)

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