H7N9 Avian Influenza

Recent News

Feb 04, 2016

News Scan for Feb 04, 2016

H7N9 cases in China
Human-to-human Legionnaires'
Avian flu in 3 African nations
Jan 28, 2016

News Scan for Jan 28, 2016

More US listeriosis
H7N9 cases in China
Ebola screening
Jan 27, 2016

Avian Flu Scan for Jan 27, 2016

H7N9 illness in China
H5N1 in Nigeria, Cote d'Ivoire
Jan 19, 2016

News Scan for Jan 19, 2016

More H5N6, H7N9 infections
New chikungunya cases
Ebola vaccine trial
Jan 14, 2016

Avian Flu Scan for Jan 14, 2016

H7N9 total rises in China
Avian flu outbreaks in Nigeria, Vietnam
Jan 12, 2016

News Scan for Jan 12, 2016

H7N9 case in China
Fecal transplant for C diff
Reassessing colistin use
Jan 11, 2016
Bird market

H5N6 kills another in China; H7N9 sickens 9

Four of the 8 H5N6 cases ever reported have been in the past 2 weeks, and H7N9 has topped 700 cases.

Jan 06, 2016

News Scan for Jan 06, 2016

H7N9 cases in China
Microcephaly in Brazil
Campylobacter detection
HPV vaccination
Vaccinia virus in dogs, opossums
Jan 04, 2016

News Scan for Jan 04, 2016

H5N6, H7N9 cases in China
US flu indicators rise
Yellow fever alert
Dec 31, 2015

News Scan for Dec 31, 2015

H7N9 case in China
Global flu update
French avian flu outbreaks

Resources & Literature

Resources

Jump to Recent Literature

 

Last updated Oct 8, 2014

Center of Excellence for Influenza Research and Surveillance (CEIRS) Resources

H7N9 PDF of epidemiologic curve, other case graphs, and map
PowerPoint slides of the H7N9 graphs and map

 

 


Latest Case Information

Frequently updated case list from FluTrackers
Graphs, charts, maps, and other info from FluTrackers
Case table and other info from Flu Wiki
Healthmap.org (search for H7N9 near top)
Disease outbreak news from WHO
Graphs, charts, maps, and other info from Virology Down Under
Google case map compiled by South China Morning Post
H7N9 infographic from Bloomberg News
Genetic analysis of virus from The Lancet (May 1, 2013)

Health Agency Documents

World Health Organization (WHO)

H7N9 page
Risk assessment (Jul 4, 2013)
H7N9 overview (May 31, 2013)
Latest case update (May 29, 2013)
Candidate vaccine viruses (May 26, 2014)
Joint mission report (May 18, 2013)
Lab guidance (May 10, 2013)
Surveillance recommendations (May 10, 2013)
Frequently asked questions (Feb 14, 2014)
Preliminary assessments of age and sex distribution (Apr 22, 2013)
RT-PCR protocol for H7N9 detection (Apr 15, 2013)
Background and summary (Apr 5, 2013)
Weekly report

US Centers for Disease Control and Prevention (CDC)

H7N9 page (updated Feb 12, 2014)
                                                                                                                           Frequently asked questions (Sep 9, 2014)
                                                                                                       Interim guidance on case definitions (Jan 10, 2014)
                                                                                          Study on risk factors (Jun 17, 2014)                                                                                                                    Top 10 pandemic response planning tips (May 30, 2013)
                                                                                   Emergence of avian influenza A(H7N9) virus causing severe human illness (May 10, 2013)                     Interim guidance for healthcare professionals (Jan 23, 2014)                                                                       Interim antiviral guidance (Sep 30, 2013)                                                                                                             Interim guidance on chemoprophylaxis with antiviral medications (Sep 30, 2013)                                 Testing recommendations for possible H7N9 infection in US (Jan 24, 2014)                                               H7N9 images

Department of Health and Human Services (HHS)

H7N9 page

Hong Kong Centre for Health Protection (CHP)
Avian influenza page

Weekly avian influenza report

Chinese Center for Disease Control and Prevention

H7N9 page
Daily updates
Frequently asked questions
Research highlights
Health tips for travelers

European Centre for Disease Prevention and Control (ECDC)

Risk assessment (Jan 27, 2014)
Epidemiologic update (Feb 7, 2014)
Case definition and case finding algorithm (Apr 26, 2013)
Genetic analysis from Euro Surveill (Apr 18, 2013)
Detection and clinical validation guidance from Euro Surveill (Apr 18, 2013)
Avian influenza page                                                                                                                                        Laboratory preparedness in EU/EEA for detection of H7N9 from Euro Surveill (Jan 30, 2014)

Public Health Agency of Canada (PHAC)

H7N9 page 
Travel health notice (Feb 17, 2014)
Public health notice (Oct 8, 2014)
Risk assessment (Oct 8, 2014)
Infection prevention and control guidance (Jun 24, 2013)

Biosafety advisory (Mar 17, 2014)

Public Health England (PHE)

Guidance for possible cases in travelers

World Organization for Animal Health (OIE)

Frequently asked questions
Statement on key role of live-bird markets (Apr 30, 2013)

Food and Agriculture Organization (FAO)

Frequently asked questions (May 27, 2013)

American Public Health Association (APHA)

What you should know now (Apr 19, 2013 blog post)

Twitter

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
CDC: Flu (@CDCFlu)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers.com (@FluTrackers)
Jason Gale (@jwgale)
GISAID AI Digest (@AIDigest)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
nprGlobalHealth (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

 

Recent Literature

Chan EYY, Cheng CKY, Tam G, et al. Knowledge, attitudes, and practices of Hong Kong population towards human A/H7N9 influenza pandemic preparedness, China, 2014. BMC Public Health 2015 Sep 22;15:943

Chen HZ, Liu S, Liu J, et al. Nosocomial co-transmission of avian influenza A(H7N9) and A(H1N1)pdm09 viruses between 2 patients with hematologic disorders. Emerg Infect Dis 2016 (published online Feb 2)

Cheng QL, Ding H, Sun Z, et al. Retrospective study of risk factors of mortality in human avian influenza A(H7N9) cases in Zhejiang Province, China, March 2013 to June 2014. Int J Infect Dis 2015 (published online Sep 13)

Dunand CJH, Leon PE, Kaur K, et al. Preexisting human antibodies neutralize recently emerged H7N9 influenza strains. J Clin Invest 2015 (published online Feb 17)

FAO. Addressing avian influenza A(H7N9): guidelines for risk communication messaging. Sep 25, 2015

Farooqui A, Leon AJ, Huang L, et al. Genetic diversity of the 2013-14 human isolates of influenza H7N9 in China. BMC Infect Dis 2015 Feb 28;15:109

Jackson LA, Campbell JD, Frey SE, et al. Effect of varying doses of a monovalent H7N9 influenza vaccine with and without AS03 and MF59 adjuvants on immune response: a randomized clinical trial. JAMA 2015 Jul 21;314(3):237-46

He F, Chen EF, Li FD, et al. Human infection and environmental contamination with avian influenza A (H7N9) virus in Zhejiang Province, China: risk trend across the three waves of infection. BMC Public Health 2015 Sep 21;15:931

Hoffmann J, Otte A, Thiele S, et al. Sex differences in H7N9 influenza A virus pathogenesis. Vaccine 2015 (published online Aug 25)

Jones JC, Sonnberg S, Webby RJ, et al. Influenza A(H7N9) virus transmission between finches and poultry. Emerg Infect Dis 2015 (published online Mar 11)

Kucharski AJ, Mills HL, Donnelly CA, et al. Transmission potential of influenza A(H7N9) virus, China, 2013-2014. Emerg Infect Dis 2015 (published online Apr 1)

Leung Y, To M, Lam T, et al. Epidemiology of human influenza A(H7N9) infection in Hong Kong. J Microbiol Immunol Infect 2015 (published online Jul 25)

Millman AJ, Havers F, Iuliano AD, et al. Detecting spread of avian influenza A(H7N9) virus beyond China. Emerg Infect Dis 2015 (published online Apr 6)

Nakamura K, Shirakura M, Suzuki Y, et al. Development of a high-yield reassortant influenza vaccine virus derived from the A/Anhui/1/2013 (H7N9) strain. Vaccine 2015 (published online Dec 1)

Qin Y, Horby PW, Tsang TK, et al. Differences in the epidemiology of human cases of avian influenza A(H7N9) and A(H5N1) viruses infection. Clin Infect Dis 2015 (published online May 4)

Root JJ, Bosco-Lauth AM, Bielefeldt-Ohmann H, et al. Experimental infection of peridomestic mammals with emergent H7N9 (A/Anhui/1/2013) influenza A virus: implications for biosecurity and wet markets. Virology 2015 (published online Nov 6)

Rudenko L, Isakova-Sivak I, Naykhin A, et al. H7N9 live attenuated influenza vaccine in healthy adults: a randomised, double-blind, placebo-controlled, phase 1 trial. Lancet Infect Dis 2015 (published online Dec 7)

Shi D, Shen S, Gan X, et al. Evaluation of commercial diagnostic assays for the specific detection of avian influenza A(H7N9) virus RNA using a quality-control panel and clinical specimens in China. PLoS One 2015 (published online Sep 11)

Skowronski DM, Chambers C, Gustafson R, et al. Avian influenza A(H7N9) virus infection in 2 travelers returning from China to Canada, January 2015. Emerg Infect Dis 2015 (published online Sep 25)

Sobhanie M, Matsuoka Y, Jegaskanda S, et al. Evaluation of the safety and immunogenicity of a candidate pandemic live attenuated influenza vaccine (pLAIV) against influenza A(H7N9). J Infect Dis 2015 (published online Dec 9)

Terajima M, Co MDT, Cruz J, et al. High antibody-dependent cellular cytotoxicity antibody titers to H5N1 and H7N9 avian influenza A viruses in healthy US adults and older children. J Infect Dis 2015 (published online Mar 20)

Wang X, Liu S, Mao H, et al. Surveillance of avian H7N9 virus in various environments of Zhejiang Province, China before and after live poultry markets were closed in 2013-2014. PLoS One 2015 Aug 26;10(8):e0135718

Wong SS, Kaplan B, Zanin M, et al. Impact of adjuvants on the immunogenicity and efficacy of split-virion H7N9 vaccine in ferrets. J Infect Dis 2015 (published online Feb 23)

Xie S, Jia W, Lin Y, et al. Third wave of influenza A(H7N9) virus from poultry, Guangdong Province, China, 2014-2015. Emerg Infect Dis 2015 (published online Jul 1)

Yang JR, Kuo CY, Huang HY, et al. Characterization of influenza A (H7N9) viruses isolated from human cases imported into Taiwan. PLoS One 2015 Mar 6;10(3):e0119792

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