Influenza, General

Recent News

Sep 25, 2017
Antiviral capsules

Antiviral combo cuts flu virus shedding but not symptoms

By day 7, both treatment groups had similar rates of viral shedding.

Sep 25, 2017

Flu Scan for Sep 25, 2017

Flu in Maryland fair pigs
H7N9 cluster analysis
Peramivir pediatric indication
H5N1 in Malaysia
Sep 20, 2017

News Scan for Sep 20, 2017

Global flu hot spots
Flu vaccine trial launch
Nigerian yellow fever
Yemen cholera
Sep 06, 2017

News Scan for Sep 06, 2017

Two MERS cases
Newer rapid flu tests
Zika-GBS link
More Cyclospora
Sep 05, 2017

Flu Scan for Sep 05, 2017

Flu and pregnancy
Global flu hot spots
More H5N8 in South Africa
Sep 01, 2017

Flu Scan for Sep 01, 2017

H1N2v case in Ohio
H7N9 death in China
Canine influenza
Aug 22, 2017

Flu Scan for Aug 22, 2017

Prior year flu vaccination
H5N8 in South Africa
Global flu hot spots
Aug 15, 2017
Tamiflu macro

ECDC experts confirm support for neuraminidase inhibitors

The review didn't find any new evidence to drive policy changes, but said more research and new antivirals are needed.

Aug 08, 2017

News Scan for Aug 08, 2017

Global flu update
H5N8 in Russia
Third papaya recall
Jul 27, 2017

News Scan for Jul 27, 2017

Saudi MERS case
Public health funding threat
Hepatitis battle snapshot
Global flu vaccine uptake

Resources & Literature

Recent Literature

AAP Committee on Infectious Diseases. Recommendations for prevention and control of influenza in children, 2017-2018. Pediatrics 2017 (published online Sep 4)

Akers IE, Weber R, Sax H, et al. Influence of time to diagnosis of severe influenza on antibiotic use, length of stay, isolation precautions and mortality: a retrospective study. Influenza Other Respir Viruses 2017 (published online Apr 5)

Ang LW, Yap J, Lee V, et al. Influenza-associated hospitalizations for cardiovascular diseases in the tropics. Am J Epidemiol 2017 (published online Feb 25)

Baranovich T, Vongphrachanh P, Ketmayoon P, et al. Antiviral drug-resistant influenza B viruses carrying H134N substitution in neuraminidase, Laos, February 2016. Emerg Infect Dis 2017 (published online Mar 17)

Beigel JH, Tebas P, Elie-Tureene MC, et al. Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study. Lancet Respir Med 2017 (published online May 15)

Beigel JH, Voell J, Munoz P, et al. Safety, tolerability, and pharmacokinetics of radavirsen (AVI-7100) an antisense oligonucleotide targeting influenza A M1/M2 translation. Br J Clin Pharmacol 2017 (published online Sep 20)

Blanton L, Alabi N, Mustaquim D, et al. Influenza activity in the United States during the 2016-17 season and composition of the 2017-18 influenza vaccine. (Update) MMWR 2017 Jun 30;66(25):668-76

Blanton L, Mustaquim D, Alabi N, et al. Update: influenza activity — United States, October 2, 2016-February 4, 2017. MMWR 2017 Feb 17;66(6):159-66

Brendish NJ, Malachira AK, Armstrong L, et al. Routine molecular point-of-care testing for respiratory viruses in adults presenting to hospital with acute respiratory illness (ResPOC): a pragmatic, open-label randomised controlled trial. Lancet Respir Med 2017 (published Apr 6)

Britton PN, Blyth CC, Macartney K, et al. The spectrum and burden of influenza-associated neurological disease in children: combined encephalitis and influenza sentinel site surveillance from Australia 2013-2015. Clin Infect Dis 2017 (published online Apr 29)

Budd A, Blanton L, Kniss K, et al. Influenza activity — United States and worldwide, May 22-September 10, 2016. (Update) MMWR 2016 Sep 23;(65)37:1008-14

Bui CM, Chughtai AA, Adam DC, et al. An overview of the epidemiology and emergence of influenza A infection in humans over time. Arch Public Health 2017 Mar 27;75:15

Caini S, Alonso WJ, Balmaseda A, et al. Characteristics of seasonal influenza A and B in Latin America: influenza surveillance data from ten countries. PLoS One 2017 Mar 27;12(3):e0174592

Caini S, Alonso WJ, Seblain CE, et al. The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe? Euro Surveill 2017 Aug 31;22(35):pii=30606

Chandrasekhar R, Sloan C, Mitchel E, et al. Social determinants of influenza hospitalization in the United States. Influenza Other Respir Viruses 2017 (published online Sep 5)

Chiu S, Black CL, Yue X, et al. Working with influenza-like illness: presenteeism among US health care personnel during the 2014-2015 influenza season.  Am J Infect Control 2017 (published online May 16)

Choi WS, Cowling BJ, Noh JY, et al. Disease burden of 2013-2014 seasonal influenza in adults in Korea. PLoS One 2017 Mar 9;12(3):e0172012

Cowling BJ, Caini S, Chotpitayasunondh T, et al. Influenza in the Asia-Pacific region: findings and recommendations from the Global Influenza Initiative. Vaccine 2017 (published online Jan 9)

Cowling BJ, Wu P, Lo JYC, et al. Population-based hospitalization burden of lineage specific influenza B children in Hong Kong, 2004-2014. Clin Infect Dis 2017 (published online Apr 6)

Deyle ER, Maher MC, Hernandez RD, et al. Global environmental drivers of influenza. Proc Natl Acad Sci USA 2016 (published online Oct 31)

Ewing A, Lee EC, Viboud C, et al. Contact, travel, and transmission: the impact of winter holidays on influenza dynamics in the United States. J Infect Dis 2016 (published online Dec 28)

Fell DB, Azziz-Baumgartner E, Baker MG, et al. Influenza epidemiology and immunization during pregnancy: final report of a World Health Organization working group. Vaccine 2017 (published online Sep 1)

Filleul L, Ranoaritiana DB, Balleydier E, et al. A major impact of the influenza seasonal epidemic on intensive care units, Reunion, April to August 2016. Euro Surveill 2016 Nov 24;21(47):pii=30405

Fougerolle S, Legrand L, Lecouturier F, et al. Genetic evolution of equine influenza virus strains (H3N8) isolated in France from 1967 to 2015 and the implications of several potential pathogenic factors. Virology 2017 (published online Mar 11)

Ghaderi S, Stordal K, Gunnes N, et al. Encephalitis after influenza and vaccination: a nationwide population-based registry study from Norway. Int J Epidemiol 2017 (published online Jul 27)

Related Practices

Health Matters - pandemic flu issue

Health Matters is a well-written, 8-page newsletter that provides essential information about pandemic influenza to the public. The articles provide essential and practical information about what to expect during a pandemic, and emphasize personal preparedness, prevention, and home care. The document is an ideal tool for placement on desks or web sites at local health departments or distribution at health fairs, clinics, and public presentations.

PIO avian flu functional exercise

The PIO avian flu functional exercise materials were adapted from a public information exercise designed to test the Ohio state communications plan and practice the formation of a joint information center.

"Protect Iowa Health" communications campaign advocates preparedness for everyone

An interactive Web site describes in English and Spanish ways in which anyone can be a preparedness hero.

Pandemic Influenza Planning Kit for Schools

The Planning Kit for Schools has the potential to increase pandemic influenza awareness, assist schools in maintaining continuity of education, and serve as a resource for the greater community. The kit carefully describes tangible steps that schools can take to plan for a pandemic, and the templates require organizations to identify specific school personnel as part of an incident command structure.

Social Distancing Protocol

The Social Distancing Protocol identifies types of social distancing, assesses the probable economic and social impact of each measure, and provides a guide for phased implementation based on WHO pandemic phase and local surveillance. These materials would be useful for review by state and local health departments, because they reference proposed decision-makers at each level of implementation.

Community Readiness Challenge

The Community Readiness Challenge encourages individuals and families to build a pandemic preparedness kit by providing detailed lists of weekly items to buy and ways to prepare for 26 weeks. The LOCC box portion of the program uses business donations to assemble personal preparedness kits for economically-disadvantaged citizens. This practice is noteworthy, because it addresses a group for which there is little focus on prevention and planning efforts.

Prioritization of public health services for pandemic influenza

A local attempt prioritized public health services and determined pertinent parameters for operation during a pandemic. The description of each prioritized service is accompanied by information on the minimum number of staff required to perform the service, necessary products, and ability of staff to perform the service from home. The document could serve as a beginning template for local agencies that have not begun the difficult discussions around public health continuity.

Medical Coordination Centers

A concept paper provides a process by which a public health department can provide statewide accessibility to select medical information and home medical treatment during an influenza pandemic. Existing Medical Coordination Centers (MCCs) are proposed as regional centers for public health operations, such as phone banks, home visit dispatch, provision of medical advice, security, Medical Reserve Corps operations, antiviral dispensing, and EMS coordination.

Caring for the sick at home when it's the only option

The hour-long DVD provides practical, detailed information on caring for ill persons, including those with influenza, at home. It is aimed at non-medical care providers.

Allocating Influenza Vaccines in Minnesota

A well-written and valuable guide on the ethics of influenza vaccine distribution was the product of a multidisciplinary work group composed of public health professionals, ethicists, healthcare providers, and legal experts. The aim of the work group was to provide ethical guidance for Minnesota's statewide pandemic planning efforts, and the group chose to focus on ethical distribution of vaccine as a scarce resource.

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