Influenza, General

Recent News

Jul 12, 2018
Sick daughter on mom's lap

BARDA support paves way for at-home flu tests

BARDA will provide $24 million in initial funds to 2 companies to advance tests for influenza A and B.

Jul 10, 2018

News Scan for Jul 10, 2018

MERS in Saudi Arabia
DRC polio outbreaks
Wellcome funds innovation
Southern Hemisphere flu rise
Australia Wolbachia mosquitoes
Jun 27, 2018

Flu Scan for Jun 27, 2018

FDA priority review for new flu drug
Southern Hemisphere flu rise
Avian flu outbreaks in poultry
Jun 26, 2018

News Scan for Jun 26, 2018

Kenya's Rift Valley fever outbreak expands
Tool visualizes flu damage in real time
Jun 13, 2018

News Scan for Jun 13, 2018

Plague case in Idaho
Tamiflu and nursing home outbreaks
Vaccine exemptions in US
Jun 12, 2018

News Scan for Jun 12, 2018

Tests rule out more Ebola cases
Colistin-resistant E coli in Vietnam
Orthobunyavirus research developments
Hospital precaution failure patterns
PCV and Hib vaccine impact
Global flu trends
Jun 11, 2018

News Scan for Jun 11, 2018

MERS household cluster
US flu deaths in kids
Polio in Venezuela
Cyclospora infections in 2 states
Measles in Brazil
H5N1, H5N8 poultry outbreaks
Jun 11, 2018

Stewardship / Resistance Scan for Jun 11, 2018

Influenza-MRSA coinfection in kids
Combo therapy for resistant Klebsiella
Jun 08, 2018
Stethoscope exam on coughing patient

CDC study: Antibiotics still widely overused for respiratory infections

Fully 41% of antibiotic prescriptions written for patients with ARIs were inappropriate.

Jun 07, 2018

News Scan for Jun 07, 2018

Pandemic surveillance
Influenza spread and humidity
Nipah contained
Measles overview in California

Resources & Literature

Recent Literature

AAP Committee on Infectious Diseases. Recommendations for prevention and control of influenza in children, 2017-2018. Pediatrics 2017 (published online Sep 4)

Abdel-Hady DM, Al Balushi RM, Al Abri BA, et al. Estimating the burden of influenza-associated hospitalization and deaths in Oman (2012-2015). Influenza Other Respir Viruses 2017 (published online Dec 5)

Adlhoch C, Snacken R, Melidou A, et al. Dominant influenza A(H3N2) and B/Yamagata virus circulation in EU/EEA, 2016/17 and 2017/18 seasons, respectively. Euro Surveill 2018 Mar 29;23(13):pii=18-00146

Ahmed M, Aleem MA, Roguski K, et al. Estimates of seasonal influenza-associated mortality in Bangladesh, 2010-2012. Influenza Other Respir Viruses 2017 (published online Dec 2)

Bedford T, Neher R. Seasonal influenza circulation patterns and projections for Sep 2017 to Sep 2018. BioRxiv 2017 Sep 26

Beigel JH, Bao Y, Beeler J, et al. Oseltamivir, amantadine, and ribavirin combination antiviral therapy versus oseltamivir monotherapy for the treatment of influenza: a multicentre, double-blind, randomised phase 2 trial. Lancet Infect Dis 2017 (published online Sep 22)

Beigel JH, Voell J, Munoz P, et al. Safety, tolerability, and pharmacokinetics of radavirsen (AVI-7100) an antisense oligonucleotide targeting influenza A M1/M2 translation. Br J Clin Pharmacol 2017 (published online Sep 20)

Biggerstaff M, Kniss K, Jernigan DB, et al. Systematic assessment of multiple routine and near-real time indicators to classify the severity of influenza seasons and pandemics in the United States, 2003-04 through 2015-2016. Am J Epidemiol 2017 (published online Oct 19)

Blanton L, Wentworth DE, Alabi N, et al. Influenza Activity — United States and Worldwide, May 21-September 23, 2017. (Update) MMWR 2017 Oct 6;66(39):1043-51

Bradley JS, Blumer JF, Romero JR, et al. Intravenous Zanamivir in hospitalized patients with influenza. Pediatrics 2017 (published online Oct 19)

Budd AP, Wentworth DE, Blanton L, et al. Influenza activity — United States, October 1, 2017-February 3, 2018. (Update) MMWR 2018 Feb 16;67(6):169-79

Caini S, Alonso WJ, Seblain CE, et al. The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe? Euro Surveill 2017 Aug 31;22(35):pii=30606

Caini S, Schellevis F, El-Guerche C, et al. Important changes in the timing of influenza epidemics in the WHO European Region over the past 20 years: virological surveillance 1996 to 2016. Euro Surveill 2018 Jan 4;23(1):pii=17-00302

Caini S, Seblain CEG, Ciblak M, et al. Epidemiology of seasonal influenza in the Middle East and North Africa regions, 2010-2016: circulating influenza A and B viruses and spatial timing of epidemics. Influenza Other Respir Viruses 2018 (published online Feb 5)

Caini S, Spreeuwenberg P, Kusznierz G, et al. Distribution of influenza virus types by age using case-based global surveillance data from twenty-nine countries, 1999-2014. BMC Infect Dis 2018 Jun 8;18:269

Casado I, Dominguez A, Toledo D, et al. Repeated influenza vaccination for preventing severe and fatal influenza infection in older adults: a multicentre case-control study. CMAJ 2018 Jan 8;190(1):E3-12

Chandrasekhar R, Sloan C, Mitchel E, et al. Social determinants of influenza hospitalization in the United States. Influenza Other Respir Viruses 2017 (published online Sep 5)

Chao WC, Tseng CH, Chien YC, et al. Association of day 4 cumulative fluid balance with mortality in critically ill patients with influenza: a multicenter retrospective cohort study in Taiwan. PLoS One 2018 Jan 9;13(1):e0190952

Cheng HY, Chen WC, Chou YR, et al. Containing influenza outbreaks with antiviral use in long-term care facilities in Taiwan, 2008-2014. Influenza Other Respir Viruses 2018 (published online Jan 17)

Coleman BL, Fadel SA, Fitzpatrick T, et al. Risk factors for serious outcomes associated with influenza illness in high- versus low- and middle-income countries: systematic literature review and meta-analysis. Influenza Other Respir Viruses 2017 (published online Dec 2)

Dahlgren FS, Shay DK, Izurieta HS, et al. Evaluating oseltamivir prescriptions in Centers for Medicare and Medicaid Services medical claims records as an indicator of seasonal influenza in the United States. Influenza Other Respir Viruses 2018 (published online Mar 5)

Dahlgren FS, Shay DK, Izurieta HS, et. Al. Evaluating oseltamivir prescriptions in Centers for Medicare and Medicaid Services medical claims records as an indicator of seasonal influenza in the United States. Influenza Other Respir Viruses 2018 (published online Mar 25)

Dawa JA, Chaves SS, Nyawanda B, et al. National burden of hospitalized and non-hospitalized influenza-associated severe acute respiratory illness in Kenya, 2012-2014. Influenza Other Respir Viruses 2017 (published online Dec 15)

Dominguez A, Romero-Tamarit A, Soldevila N, et al. Effectiveness of antiviral treatment in preventing death in severe hospitalised influenza cases over six seasons. Epidemiol Infect 2018 (published online Apr 2)

Dugan VG, Blanton L, Elal AIA, et al. Influenza activity — United States, October 1-November 25, 2017. (Update) MMWR 2017 Dec 8;66(48):1318-26

Related Practices

Health Matters - pandemic flu issue

Health Matters is a well-written, 8-page newsletter that provides essential information about pandemic influenza to the public. The articles provide essential and practical information about what to expect during a pandemic, and emphasize personal preparedness, prevention, and home care. The document is an ideal tool for placement on desks or web sites at local health departments or distribution at health fairs, clinics, and public presentations.

PIO avian flu functional exercise

The PIO avian flu functional exercise materials were adapted from a public information exercise designed to test the Ohio state communications plan and practice the formation of a joint information center.

"Protect Iowa Health" communications campaign advocates preparedness for everyone

An interactive Web site describes in English and Spanish ways in which anyone can be a preparedness hero.

Pandemic Influenza Planning Kit for Schools

The Planning Kit for Schools has the potential to increase pandemic influenza awareness, assist schools in maintaining continuity of education, and serve as a resource for the greater community. The kit carefully describes tangible steps that schools can take to plan for a pandemic, and the templates require organizations to identify specific school personnel as part of an incident command structure.

Social Distancing Protocol

The Social Distancing Protocol identifies types of social distancing, assesses the probable economic and social impact of each measure, and provides a guide for phased implementation based on WHO pandemic phase and local surveillance. These materials would be useful for review by state and local health departments, because they reference proposed decision-makers at each level of implementation.

Community Readiness Challenge

The Community Readiness Challenge encourages individuals and families to build a pandemic preparedness kit by providing detailed lists of weekly items to buy and ways to prepare for 26 weeks. The LOCC box portion of the program uses business donations to assemble personal preparedness kits for economically-disadvantaged citizens. This practice is noteworthy, because it addresses a group for which there is little focus on prevention and planning efforts.

Prioritization of public health services for pandemic influenza

A local attempt prioritized public health services and determined pertinent parameters for operation during a pandemic. The description of each prioritized service is accompanied by information on the minimum number of staff required to perform the service, necessary products, and ability of staff to perform the service from home. The document could serve as a beginning template for local agencies that have not begun the difficult discussions around public health continuity.

Medical Coordination Centers

A concept paper provides a process by which a public health department can provide statewide accessibility to select medical information and home medical treatment during an influenza pandemic. Existing Medical Coordination Centers (MCCs) are proposed as regional centers for public health operations, such as phone banks, home visit dispatch, provision of medical advice, security, Medical Reserve Corps operations, antiviral dispensing, and EMS coordination.

Caring for the sick at home when it's the only option

The hour-long DVD provides practical, detailed information on caring for ill persons, including those with influenza, at home. It is aimed at non-medical care providers.

Allocating Influenza Vaccines in Minnesota

A well-written and valuable guide on the ethics of influenza vaccine distribution was the product of a multidisciplinary work group composed of public health professionals, ethicists, healthcare providers, and legal experts. The aim of the work group was to provide ethical guidance for Minnesota's statewide pandemic planning efforts, and the group chose to focus on ethical distribution of vaccine as a scarce resource.

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