Influenza, General

Recent News

Feb 22, 2017

News Scan for Feb 22, 2017

Global flu, H3N2
Bipartisan pro-vaccine letter
Yemen cholera
Feb 17, 2017
Doctor examining girl

Flu widespread in 46 states; 9 more kids' deaths reported

The H3N2 strain continues to dominate, especially affecting the elderly.

Feb 10, 2017
nasal swab

Flu widespread in 43 states; 5 more fatal cases in kids

Flu markers rose to their highest points yet, as influenza B detections rose slightly, typical for the later months of the flu season.

Feb 03, 2017
Sick child

CDC: Widespread flu leads to 7 new deaths in kids

Clinic visits and hospitalizations for flu rose again last week, with the disease now widespread in 40 states and Puerto Rico.

Jan 27, 2017
Hands of elderly patient

CDC: Flu now widespread in 37 states

For the first time this season, the marker for pneumonia and flu deaths rose above the seasonal and epidemic thresholds.

Jan 25, 2017

Flu Scan for Jan 25, 2017

H7N9 cases climb
Global flu increases
Jan 20, 2017
ICU baby

US flu numbers rise as 2 more pediatric deaths noted

Flu markers rose again last week, with disease activity now widespread in 29 states.

Jan 13, 2017
Elderly patient in hospital

US flu season picks up as European levels stay high

The US reports widespread flu and 3 pediatric deaths, while Europe is being hit hard.

Jan 10, 2017

News Scan for Jan 10, 2017

Trump taps anti-vaxxer
DURC recommendations
Saudi MERS cases
MCR-1 in pigs
Flu in Northern Hemisphere
Madagascar plague
Jan 06, 2017
Flu vax supplies

US flu activity shows steady rise

Flu is now widespread in 12 states, with a growing percentage of clinic visits for flu and hospitalization rates rising quickly for seniors, a group typically hit hard by H3N2.

Resources & Literature

Recent Literature

Abente EJ, Anderson TK, Rajao DS, et al. The avian-origin H3N2 canine influenza virus that recently emerged in the United States has limited replication in swine. Influenza Other Respir Viruses 2016 (published online Apr 25)

Ballester J, Rodo X, Robine JM, et al. European seasonal mortality and influenza incidence due to winter temperature variability. (Letter) Nat Clim Chang 2016 (published online Jul 4)

Blanton L, Mustaquim D, Alabi N, et al. Update: influenza activity — United States, October 2, 2016-February 4, 2017. MMWR 2017 Feb 17;66(6):159-66

Broberg E, Melidou A, Prosenc K, et al. Predominance of influenza A(H1N1)PDM09 virus genetic subclade 6B.1 and influenza B/Victoria lineage viruses at the start of the 2015/16 influenza season in Europe. Euro Surveill 2016 Mar 31;21(13):pii=30184

Budd A, Blanton L, Kniss K, et al. Influenza activity — United States and worldwide, May 22-September 10, 2016. (Update) MMWR 2016 Sep 23;(65)37:1008-14

Cowling BJ, Caini S, Chotpitayasunondh T, et al. Influenza in the Asia-Pacific region: findings and recommendations from the Global Influenza Initiative. Vaccine 2017 (published online Jan 9)

Davlin SL, Blanton L, Kniss K, et al. Influenza activity —United States, 2015-16 season and composition of the 2016-17 influenza vaccine. MMWR 2016 Jun 10;65(22):567-75

Descalzo MA, Clara W, Guzman G, et al. Estimating the burden of influenza-associated hospitalizations and deaths in Central America. Influenza Other Respir Viruses 2016 (published online Mar 4)

Deyle ER, Maher MC, Hernandez RD, et al. Global environmental drivers of influenza. Proc Natl Acad Sci USA 2016 (published online Oct 31)

Ewing A, Lee EC, Viboud C, et al. Contact, travel, and transmission: the impact of winter holidays on influenza dynamics in the United States. J Infect Dis 2016 (published online Dec 28)

Fell DB, Buckeridge DL, Platt RW, et al. Circulating influenza virus and adverse pregnancy outcomes: a time-series study. Am J Epidemiol 2016 (published online Jul 22)

Ferguson L, Olivier AK, Genova S, et al. Pathogenesis of influenza D virus in cattle. J Virol 2016 (published online Mar 30)

Filleul L, Ranoaritiana DB, Balleydier E, et al. A major impact of the influenza seasonal epidemic on intensive care units, Reunion, April to August 2016. Euro Surveill 2016 Nov 24;21(47):pii=30405

Fleming DM, Durnall H, Warburton F, et al. Is the onset of influenza in the community age-related? Epidemiol Infect 2016 (published online Apr 8)

Furuya-Kanamori L, Cox M, Milinovich GJ, et al. Heterogeneous and dynamic prevalence of asymptomatic influenza virus infections. Emerg Infect Dis 2016 (published online May 11)

Harvala H, Frampton D, Grant P, et al. Emergence of a novel subclade of influenza A(H3N2) virus in London, December 2016 to January 2017. Euro Surveill 2017 Feb 23;22(8):pii=30466

Hendriks W, Boshuizen H, Dekkers A, et al. Temporal cross-correlation between influenza-like illnesses and invasive pneumococcal disease in the Netherlands. Influenza Other Respir Viruses 2016 (published online Dec 10)

Hirose R, Daidoji T, Naito Y, et al. Long term detection of seasonal influenza RNA in faeces and intestine. Clin Microbiol Infect 2016 (published online Jul 14)

Holbrook BC, D’Agostino RB, Parks GD, et al. Adjuvanting an inactivated influenza vaccine with flagellin improves the function and quantity of the long-term antibody response in a nonhuman primate neonate model. Vaccine 2016 Aug 8

Hurt AC, Su YCF, Aban M, et al. Evidence for the introduction, reassortment and persistence of diverse influenza A viruses in Antarctica. J Virol 2016 (published online Aug 17)

Ilyicheva T, Durymanov A, Susloparov I, et al. Fatal cases of seasonal influenza in Russia in 2015-2016. PLoS One 2016 Oct 24;11(10):e0165332

Jones AH, Ampofo W, Akuffo R, et al. Sentinel surveillance for influenza among severe acute respiratory infection and acute febrile illness inpatients at three hospitals in Ghana. Influenza Other Respir Viruses 2016 (published online May 30)

Kamal MA, Smith PF, Chaiyakunapruk N, et al. Interdisciplinary pharmacometrics linking oseltamivir pharmacology, influenza epidemiology, and health economics to inform antiviral use in pandemics. Br J Clin Pharmacol 2017 (published online Fab 8)

Kashiwagi S, Watanabe A, Ikematsu H, et al. Long-acting neuraminidase inhibitor laninamivir octanoate as post-exposure prophylaxis for influenza. Clin Infect Dis 2016 (published online Apr 26)

Klein EY, Monteforte B, Gupta A, et al. The frequency of influenza and bacterial co-infection: a systematic review and meta-analysis. Influenza Other Respir Viruses 2016 (published online May 27)

Related Practices

Health Matters - pandemic flu issue

Health Matters is a well-written, 8-page newsletter that provides essential information about pandemic influenza to the public. The articles provide essential and practical information about what to expect during a pandemic, and emphasize personal preparedness, prevention, and home care. The document is an ideal tool for placement on desks or web sites at local health departments or distribution at health fairs, clinics, and public presentations.

PIO avian flu functional exercise

The PIO avian flu functional exercise materials were adapted from a public information exercise designed to test the Ohio state communications plan and practice the formation of a joint information center.

"Protect Iowa Health" communications campaign advocates preparedness for everyone

An interactive Web site describes in English and Spanish ways in which anyone can be a preparedness hero.

Pandemic Influenza Planning Kit for Schools

The Planning Kit for Schools has the potential to increase pandemic influenza awareness, assist schools in maintaining continuity of education, and serve as a resource for the greater community. The kit carefully describes tangible steps that schools can take to plan for a pandemic, and the templates require organizations to identify specific school personnel as part of an incident command structure.

Social Distancing Protocol

The Social Distancing Protocol identifies types of social distancing, assesses the probable economic and social impact of each measure, and provides a guide for phased implementation based on WHO pandemic phase and local surveillance. These materials would be useful for review by state and local health departments, because they reference proposed decision-makers at each level of implementation.

Community Readiness Challenge

The Community Readiness Challenge encourages individuals and families to build a pandemic preparedness kit by providing detailed lists of weekly items to buy and ways to prepare for 26 weeks. The LOCC box portion of the program uses business donations to assemble personal preparedness kits for economically-disadvantaged citizens. This practice is noteworthy, because it addresses a group for which there is little focus on prevention and planning efforts.

Prioritization of public health services for pandemic influenza

A local attempt prioritized public health services and determined pertinent parameters for operation during a pandemic. The description of each prioritized service is accompanied by information on the minimum number of staff required to perform the service, necessary products, and ability of staff to perform the service from home. The document could serve as a beginning template for local agencies that have not begun the difficult discussions around public health continuity.

Medical Coordination Centers

A concept paper provides a process by which a public health department can provide statewide accessibility to select medical information and home medical treatment during an influenza pandemic. Existing Medical Coordination Centers (MCCs) are proposed as regional centers for public health operations, such as phone banks, home visit dispatch, provision of medical advice, security, Medical Reserve Corps operations, antiviral dispensing, and EMS coordination.

Caring for the sick at home when it's the only option

The hour-long DVD provides practical, detailed information on caring for ill persons, including those with influenza, at home. It is aimed at non-medical care providers.

Allocating Influenza Vaccines in Minnesota

A well-written and valuable guide on the ethics of influenza vaccine distribution was the product of a multidisciplinary work group composed of public health professionals, ethicists, healthcare providers, and legal experts. The aim of the work group was to provide ethical guidance for Minnesota's statewide pandemic planning efforts, and the group chose to focus on ethical distribution of vaccine as a scarce resource.

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