Influenza, General

Recent News

Feb 19, 2018
Drawing vaccine from a vial

Senate bill would jump-start universal flu vaccine efforts

The proposed law would direct $200 million a year for 5 years to research.

Feb 16, 2018
Mother holding child's hand in the hospital

CDC: Flu activity still high, deaths in kids climb to 84

The rate of ILI clinic visits drops slightly, but 22 new deaths in kids show the season is not relenting.

Feb 15, 2018

Flu Scan for Feb 15, 2018

High-dose flu vaccine in elderly
US seasonal flu burden
Feb 13, 2018
Baby boy on oxygen

Study shows youngest kids most at risk of flu death

A probe of child flu deaths over 6 seasons found vaccination gaps and a somber reminder that even healthy kids can succumb.

Feb 09, 2018
Woman in ICU

Flu-like illness in US reaches 2009 pandemic levels

"This year is not a pandemic, but the high ILI is a sign of the severity," CDC Director Anne Schuchat says.

Feb 09, 2018

News Scan for Feb 09, 2018

Olympics norovirus outbreak
2018 priority diseases
Polio in Afghanistan, DRC
Guinea Lassa fever case
Far-UV light against flu
Feb 07, 2018

News Scan for Feb 07, 2018

Winter Olympics health advisory
South Sudan cholera winds down
Feb 06, 2018

Flu Scan for Feb 06, 2018

High Northern Hemisphere flu levels
Avian flu in UK, France
Feb 02, 2018
Woman sick in bed

CDC: Flu still rising across US; 16 new pediatric deaths

By every metric, this H3N2-dominated season is measuring up as a bad one.

Jan 29, 2018

News Scan for Jan 29, 2018

MERS in Saudi Arabia
North Korea H1N1 outbreak
Avian flu in Iraq, South Korea
Fast-tracked Zika vaccine
Aerosolized toilet flushes
New botulism toxin

Resources & Literature

Recent Literature

AAP Committee on Infectious Diseases. Recommendations for prevention and control of influenza in children, 2017-2018. Pediatrics 2017 (published online Sep 4)

Abdel-Hady DM, Al Balushi RM, Al Abri BA, et al. Estimating the burden of influenza-associated hospitalization and deaths in Oman (2012-2015). Influenza Other Respir Viruses 2017 (published online Dec 5)

Ahmed M, Aleem MA, Roguski K, et al. Estimates of seasonal influenza-associated mortality in Bangladesh, 2010-2012. Influenza Other Respir Viruses 2017 (published online Dec 2)

Akers IE, Weber R, Sax H, et al. Influence of time to diagnosis of severe influenza on antibiotic use, length of stay, isolation precautions and mortality: a retrospective study. Influenza Other Respir Viruses 2017 (published online Apr 5)

Ang LW, Yap J, Lee V, et al. Influenza-associated hospitalizations for cardiovascular diseases in the tropics. Am J Epidemiol 2017 (published online Feb 25)

Baranovich T, Vongphrachanh P, Ketmayoon P, et al. Antiviral drug-resistant influenza B viruses carrying H134N substitution in neuraminidase, Laos, February 2016. Emerg Infect Dis 2017 (published online Mar 17)

Bedford T, Neher R. Seasonal influenza circulation patterns and projections for Sep 2017 to Sep 2018. BioRxiv 2017 Sep 26

Beigel JH, Bao Y, Beeler J, et al. Oseltamivir, amantadine, and ribavirin combination antiviral therapy versus oseltamivir monotherapy for the treatment of influenza: a multicentre, double-blind, randomised phase 2 trial. Lancet Infect Dis 2017 (published online Sep 22)

Beigel JH, Tebas P, Elie-Tureene MC, et al. Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study. Lancet Respir Med 2017 (published online May 15)

Beigel JH, Voell J, Munoz P, et al. Safety, tolerability, and pharmacokinetics of radavirsen (AVI-7100) an antisense oligonucleotide targeting influenza A M1/M2 translation. Br J Clin Pharmacol 2017 (published online Sep 20)

Biggerstaff M, Kniss K, Jernigan DB, et al. Systematic assessment of multiple routine and near-real time indicators to classify the severity of influenza seasons and pandemics in the United States, 2003-04 through 2015-2016. Am J Epidemiol 2017 (published online Oct 19)

Blanton L, Alabi N, Mustaquim D, et al. Influenza activity in the United States during the 2016-17 season and composition of the 2017-18 influenza vaccine. (Update) MMWR 2017 Jun 30;66(25):668-76

Blanton L, Mustaquim D, Alabi N, et al. Update: influenza activity — United States, October 2, 2016-February 4, 2017. MMWR 2017 Feb 17;66(6):159-66

Blanton L, Wentworth DE, Alabi N, et al. Influenza Activity — United States and Worldwide, May 21-September 23, 2017. (Update) MMWR 2017 Oct 6;66(39):1043-51

Bradley JS, Blumer JF, Romero JR, et al. Intravenous Zanamivir in hospitalized patients with influenza. Pediatrics 2017 (published online Oct 19)

Brendish NJ, Malachira AK, Armstrong L, et al. Routine molecular point-of-care testing for respiratory viruses in adults presenting to hospital with acute respiratory illness (ResPOC): a pragmatic, open-label randomised controlled trial. Lancet Respir Med 2017 (published Apr 6)

Britton PN, Blyth CC, Macartney K, et al. The spectrum and burden of influenza-associated neurological disease in children: combined encephalitis and influenza sentinel site surveillance from Australia 2013-2015. Clin Infect Dis 2017 (published online Apr 29)

Budd AP, Wentworth DE, Blanton L, et al. Influenza activity — United States, October 1, 2017-February 3, 2018. (Update) MMWR 2018 Feb 16;67(6):169-79

Bui CM, Chughtai AA, Adam DC, et al. An overview of the epidemiology and emergence of influenza A infection in humans over time. Arch Public Health 2017 Mar 27;75:15

Caini S, Alonso WJ, Balmaseda A, et al. Characteristics of seasonal influenza A and B in Latin America: influenza surveillance data from ten countries. PLoS One 2017 Mar 27;12(3):e0174592

Caini S, Alonso WJ, Seblain CE, et al. The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe? Euro Surveill 2017 Aug 31;22(35):pii=30606

Caini S, Schellevis F, El-Guerche C, et al. Important changes in the timing of influenza epidemics in the WHO European Region over the past 20 years: virological surveillance 1996 to 2016. Euro Surveill 2018 Jan 4;23(1):pii=17-00302

Caini S, Seblain CEG, Ciblak M, et al. Epidemiology of seasonal influenza in the Middle East and North Africa regions, 2010-2016: circulating influenza A and B viruses and spatial timing of epidemics. Influenza Other Respir Viruses 2018 (published online Feb 5)

Casado I, Dominguez A, Toledo D, et al. Repeated influenza vaccination for preventing severe and fatal influenza infection in older adults: a multicentre case-control study. CMAJ 2018 Jan 8;190(1):E3-12

Chandrasekhar R, Sloan C, Mitchel E, et al. Social determinants of influenza hospitalization in the United States. Influenza Other Respir Viruses 2017 (published online Sep 5)

Related Practices

Health Matters - pandemic flu issue

Health Matters is a well-written, 8-page newsletter that provides essential information about pandemic influenza to the public. The articles provide essential and practical information about what to expect during a pandemic, and emphasize personal preparedness, prevention, and home care. The document is an ideal tool for placement on desks or web sites at local health departments or distribution at health fairs, clinics, and public presentations.

PIO avian flu functional exercise

The PIO avian flu functional exercise materials were adapted from a public information exercise designed to test the Ohio state communications plan and practice the formation of a joint information center.

"Protect Iowa Health" communications campaign advocates preparedness for everyone

An interactive Web site describes in English and Spanish ways in which anyone can be a preparedness hero.

Pandemic Influenza Planning Kit for Schools

The Planning Kit for Schools has the potential to increase pandemic influenza awareness, assist schools in maintaining continuity of education, and serve as a resource for the greater community. The kit carefully describes tangible steps that schools can take to plan for a pandemic, and the templates require organizations to identify specific school personnel as part of an incident command structure.

Social Distancing Protocol

The Social Distancing Protocol identifies types of social distancing, assesses the probable economic and social impact of each measure, and provides a guide for phased implementation based on WHO pandemic phase and local surveillance. These materials would be useful for review by state and local health departments, because they reference proposed decision-makers at each level of implementation.

Community Readiness Challenge

The Community Readiness Challenge encourages individuals and families to build a pandemic preparedness kit by providing detailed lists of weekly items to buy and ways to prepare for 26 weeks. The LOCC box portion of the program uses business donations to assemble personal preparedness kits for economically-disadvantaged citizens. This practice is noteworthy, because it addresses a group for which there is little focus on prevention and planning efforts.

Prioritization of public health services for pandemic influenza

A local attempt prioritized public health services and determined pertinent parameters for operation during a pandemic. The description of each prioritized service is accompanied by information on the minimum number of staff required to perform the service, necessary products, and ability of staff to perform the service from home. The document could serve as a beginning template for local agencies that have not begun the difficult discussions around public health continuity.

Medical Coordination Centers

A concept paper provides a process by which a public health department can provide statewide accessibility to select medical information and home medical treatment during an influenza pandemic. Existing Medical Coordination Centers (MCCs) are proposed as regional centers for public health operations, such as phone banks, home visit dispatch, provision of medical advice, security, Medical Reserve Corps operations, antiviral dispensing, and EMS coordination.

Caring for the sick at home when it's the only option

The hour-long DVD provides practical, detailed information on caring for ill persons, including those with influenza, at home. It is aimed at non-medical care providers.

Allocating Influenza Vaccines in Minnesota

A well-written and valuable guide on the ethics of influenza vaccine distribution was the product of a multidisciplinary work group composed of public health professionals, ethicists, healthcare providers, and legal experts. The aim of the work group was to provide ethical guidance for Minnesota's statewide pandemic planning efforts, and the group chose to focus on ethical distribution of vaccine as a scarce resource.

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