Influenza, General

Recent News

Dec 14, 2017
Elderly hand in hospital bed

New estimate shows higher global rate of deaths from flu

About 291,000 to 646,000 people in the world die from seasonal flu each year, experts estimate.

Dec 12, 2017

News Scan for Dec 12, 2017

Smallpox drug review
Flu rise in North America, Asia
Cholera in Kenya, Zambia
Dec 08, 2017
Get a flu shot sign in Chicago

US flu continues to rise and expand its reach

The number of states reporting geographically widespread flu rose from 4 to 7.

Dec 04, 2017
Physician with critical patient

Studies spotlight heavy burden of severe flu in developing nations

A meta-analysis finds 4 key differences between low-income and high-income nations involving children, pregnant women, and those with certain underlying medical conditions.

Dec 01, 2017
Woman with flu

US flu data show season ramping up

Flulike illness is high in 3 southern states, flu is widespread in 4 states, and one marker has topped the national baseline.

Nov 28, 2017
Busy waiting room

CDC sees some signs of an early flu season

The agency reports increased activity overall, 5 pediatric deaths, and a variant H1N1 infection in Iowa.

Nov 27, 2017

News Scan for Nov 27, 2017

Saudi MERS cases
Peds Tamiflu review
Polio in Syria
Brazilian yellow fever
Lyme diagnosis
Nov 17, 2017

News Scan for Nov 17, 2017

Saudi MERS case
Polio in Afghanistan
Tainted tiny turtles
Pandemic planning guide
US flu rises
Nov 15, 2017

News Scan for Nov 15, 2017

Northern Hemisphere flu uptick
Flu vaccine protection by age
Madagascar plague declines
Nov 13, 2017

News Scan for Nov 13, 2017

New MERS cases
Yellow fever in Nigeria
HHS secretary nomination
Legionnaires' at Disney
Canadian flu cost estimate

Resources & Literature

Recent Literature

AAP Committee on Infectious Diseases. Recommendations for prevention and control of influenza in children, 2017-2018. Pediatrics 2017 (published online Sep 4)

Abdel-Hady DM, Al Balushi RM, Al Abri BA, et al. Estimating the burden of influenza-associated hospitalization and deaths in Oman (2012-2015). Influenza Other Respir Viruses 2017 (published online Dec 5)

Ahmed M, Aleem MA, Roguski K, et al. Estimates of seasonal influenza-associated mortality in Bangladesh, 2010-2012. Influenza Other Respir Viruses 2017 (published online Dec 2)

Akers IE, Weber R, Sax H, et al. Influence of time to diagnosis of severe influenza on antibiotic use, length of stay, isolation precautions and mortality: a retrospective study. Influenza Other Respir Viruses 2017 (published online Apr 5)

Ang LW, Yap J, Lee V, et al. Influenza-associated hospitalizations for cardiovascular diseases in the tropics. Am J Epidemiol 2017 (published online Feb 25)

Baranovich T, Vongphrachanh P, Ketmayoon P, et al. Antiviral drug-resistant influenza B viruses carrying H134N substitution in neuraminidase, Laos, February 2016. Emerg Infect Dis 2017 (published online Mar 17)

Bedford T, Neher R. Seasonal influenza circulation patterns and projections for Sep 2017 to Sep 2018. BioRxiv 2017 Sep 26

Beigel JH, Bao Y, Beeler J, et al. Oseltamivir, amantadine, and ribavirin combination antiviral therapy versus oseltamivir monotherapy for the treatment of influenza: a multicentre, double-blind, randomised phase 2 trial. Lancet Infect Dis 2017 (published online Sep 22)

Beigel JH, Tebas P, Elie-Tureene MC, et al. Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study. Lancet Respir Med 2017 (published online May 15)

Beigel JH, Voell J, Munoz P, et al. Safety, tolerability, and pharmacokinetics of radavirsen (AVI-7100) an antisense oligonucleotide targeting influenza A M1/M2 translation. Br J Clin Pharmacol 2017 (published online Sep 20)

Biggerstaff M, Kniss K, Jernigan DB, et al. Systematic assessment of multiple routine and near-real time indicators to classify the severity of influenza seasons and pandemics in the United States, 2003-04 through 2015-2016. Am J Epidemiol 2017 (published online Oct 19)

Blanton L, Alabi N, Mustaquim D, et al. Influenza activity in the United States during the 2016-17 season and composition of the 2017-18 influenza vaccine. (Update) MMWR 2017 Jun 30;66(25):668-76

Blanton L, Mustaquim D, Alabi N, et al. Update: influenza activity — United States, October 2, 2016-February 4, 2017. MMWR 2017 Feb 17;66(6):159-66

Blanton L, Wentworth DE, Alabi N, et al. Influenza Activity — United States and Worldwide, May 21-September 23, 2017. (Update) MMWR 2017 Oct 6;66(39):1043-51

Bradley JS, Blumer JF, Romero JR, et al. Intravenous Zanamivir in hospitalized patients with influenza. Pediatrics 2017 (published online Oct 19)

Brendish NJ, Malachira AK, Armstrong L, et al. Routine molecular point-of-care testing for respiratory viruses in adults presenting to hospital with acute respiratory illness (ResPOC): a pragmatic, open-label randomised controlled trial. Lancet Respir Med 2017 (published Apr 6)

Britton PN, Blyth CC, Macartney K, et al. The spectrum and burden of influenza-associated neurological disease in children: combined encephalitis and influenza sentinel site surveillance from Australia 2013-2015. Clin Infect Dis 2017 (published online Apr 29)

Bui CM, Chughtai AA, Adam DC, et al. An overview of the epidemiology and emergence of influenza A infection in humans over time. Arch Public Health 2017 Mar 27;75:15

Caini S, Alonso WJ, Balmaseda A, et al. Characteristics of seasonal influenza A and B in Latin America: influenza surveillance data from ten countries. PLoS One 2017 Mar 27;12(3):e0174592

Caini S, Alonso WJ, Seblain CE, et al. The spatiotemporal characteristics of influenza A and B in the WHO European Region: can one define influenza transmission zones in Europe? Euro Surveill 2017 Aug 31;22(35):pii=30606

Chandrasekhar R, Sloan C, Mitchel E, et al. Social determinants of influenza hospitalization in the United States. Influenza Other Respir Viruses 2017 (published online Sep 5)

Chiu S, Black CL, Yue X, et al. Working with influenza-like illness: presenteeism among US health care personnel during the 2014-2015 influenza season.  Am J Infect Control 2017 (published online May 16)

Choi WS, Cowling BJ, Noh JY, et al. Disease burden of 2013-2014 seasonal influenza in adults in Korea. PLoS One 2017 Mar 9;12(3):e0172012

Coleman BL, Fadel SA, Fitzpatrick T, et al. Risk factors for serious outcomes associated with influenza illness in high- versus low- and middle-income countries: systematic literature review and meta-analysis. Influenza Other Respir Viruses 2017 (published online Dec 2)

Cowling BJ, Caini S, Chotpitayasunondh T, et al. Influenza in the Asia-Pacific region: findings and recommendations from the Global Influenza Initiative. Vaccine 2017 (published online Jan 9)

Related Practices

Health Matters - pandemic flu issue

Health Matters is a well-written, 8-page newsletter that provides essential information about pandemic influenza to the public. The articles provide essential and practical information about what to expect during a pandemic, and emphasize personal preparedness, prevention, and home care. The document is an ideal tool for placement on desks or web sites at local health departments or distribution at health fairs, clinics, and public presentations.

PIO avian flu functional exercise

The PIO avian flu functional exercise materials were adapted from a public information exercise designed to test the Ohio state communications plan and practice the formation of a joint information center.

"Protect Iowa Health" communications campaign advocates preparedness for everyone

An interactive Web site describes in English and Spanish ways in which anyone can be a preparedness hero.

Pandemic Influenza Planning Kit for Schools

The Planning Kit for Schools has the potential to increase pandemic influenza awareness, assist schools in maintaining continuity of education, and serve as a resource for the greater community. The kit carefully describes tangible steps that schools can take to plan for a pandemic, and the templates require organizations to identify specific school personnel as part of an incident command structure.

Social Distancing Protocol

The Social Distancing Protocol identifies types of social distancing, assesses the probable economic and social impact of each measure, and provides a guide for phased implementation based on WHO pandemic phase and local surveillance. These materials would be useful for review by state and local health departments, because they reference proposed decision-makers at each level of implementation.

Community Readiness Challenge

The Community Readiness Challenge encourages individuals and families to build a pandemic preparedness kit by providing detailed lists of weekly items to buy and ways to prepare for 26 weeks. The LOCC box portion of the program uses business donations to assemble personal preparedness kits for economically-disadvantaged citizens. This practice is noteworthy, because it addresses a group for which there is little focus on prevention and planning efforts.

Prioritization of public health services for pandemic influenza

A local attempt prioritized public health services and determined pertinent parameters for operation during a pandemic. The description of each prioritized service is accompanied by information on the minimum number of staff required to perform the service, necessary products, and ability of staff to perform the service from home. The document could serve as a beginning template for local agencies that have not begun the difficult discussions around public health continuity.

Medical Coordination Centers

A concept paper provides a process by which a public health department can provide statewide accessibility to select medical information and home medical treatment during an influenza pandemic. Existing Medical Coordination Centers (MCCs) are proposed as regional centers for public health operations, such as phone banks, home visit dispatch, provision of medical advice, security, Medical Reserve Corps operations, antiviral dispensing, and EMS coordination.

Caring for the sick at home when it's the only option

The hour-long DVD provides practical, detailed information on caring for ill persons, including those with influenza, at home. It is aimed at non-medical care providers.

Allocating Influenza Vaccines in Minnesota

A well-written and valuable guide on the ethics of influenza vaccine distribution was the product of a multidisciplinary work group composed of public health professionals, ethicists, healthcare providers, and legal experts. The aim of the work group was to provide ethical guidance for Minnesota's statewide pandemic planning efforts, and the group chose to focus on ethical distribution of vaccine as a scarce resource.

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