MERS-CoV

Middle East respiratory syndrome coronavirus

Recent News

Aug 21, 2014

News Scan for Aug 21, 2014

Controlling MRSA
Marburg virus drug trial
Vaccine-linked polio in Texas
A new animal model for MERS
Aug 19, 2014

News Scan for Aug 19, 2014

Flu evolution in pigs
MERS-CoV in African camels
Lab incident findings
Vaccine-resistant polio
WHO gets large Saudi gift for Iraq
Aug 18, 2014

News Scan for Aug 18, 2014

Chikungunya update
MERS death
MERS in camels
Aug 12, 2014

News Scan for Aug 12, 2014

New Saudi MERS case
Synthetic malaria drug batches
Hepatitis C epidemic
Neuro arbovirus cases in kids
Aug 11, 2014

News Scan for Aug 11, 2014

Another chikungunya spike
MERS case in Saudi Arabia
Salmonella from baby poultry
Polio vaccination in Iraq
Aug 05, 2014

News Scan for Aug 05, 2014

MERS surveillance in England
Foodborne disease outbreak data
Jul 28, 2014

News Scan for Jul 28, 2014

Fist bump for hygiene
H5N8 in Korea
Oral drugs for hepatitis C
Saudi MERS update
Jul 25, 2014

News Scan for Jul 25, 2014

Feed antibiotics ruling
US-Mexico produce safety
MERS and bioterrorism?
Global hepatitis battle
Jul 23, 2014

Iran notes 5th MERS case; Saudis extend case-free streak

A 67-year-old Iranian woman died of MERS on Jun 25, , the WHO said, marking the country's second fatal case.

Jul 22, 2014

Study: Pieces of MERS-CoV found in air of camel barn

The findings raise the possibility of airborne spread, but an expert called them preliminary.

Resources & Literature

Resources

 

Jump to Recent Literature

 

Last updated Aug 22, 2014

Latest Cases & General Information

Frequently updated case list from FluTrackersTransmission electron micrograph of Middle East Respiratory Syndrome Coronavirus
Disease outbreak news from WHO
Maia Majumder, MPH, MERS resources on Tumblr
Virology Down Under MERS-CoV page
Naming of MERS-CoV from Science (May 6, 2013)
Genetic sequence of MERS-CoV from PHE

Health Agency Documents

World Health Organization (WHO)

MERS-CoV page 
List of latest case updates
Summary updates landing page
Latest risk assessment (Apr 24, 2014)
Frequently asked questions (May 9, 2014)
Interim Case Definitions (Jul 3, 2013)
Guidance on conducting case-control studies (Jul 15, 2014)
Interim surveillance recommendations (Jun 27, 2013)
Interim recommendations for laboratory testing (Sep 16, 2o13)
Seroepidemiological investigation of contacts (Nov 19, 2013)                                                                     Risk factors of infection among health care personnel (Jan 27, 2014)
Guidance for health care professionals (May 6, 2013)
Clinical management (Feb 11, 2013)
Home care for patients with MERS-CoV infection (Aug 8, 2013)
Travel recommendations (Jun 5, 2013)
Travel advice for pilgrims (Jun 3, 2014)
Naming of the novel coronavirus (May 28, 2013)

US Centers for Disease Control and Prevention (CDC)

MERS-CoV page
Press release on first US case
(May 2, 2014)
Press release on clearing of contacts of first 2 US cases (Jun 17, 2014)
Health Alert Network advisory (May 3, 2014)
Frequently asked questions
(Aug 4, 2014)
Case definitions (Jun 25, 2014)
Interim guidance for healthcare professionals (Jul 29, 2014)
Guidance for travelers (May 21, 2014)
Infection prevention and control guidelines (Jul 11, 2014)
Information and guidance for clinicians (Jun 18, 2013)
Guidance on air medical transport for MERS patients (Jul 3, 2014)

Interim guidance for airline crew
(Mar 10, 2014)
Guidelines for evaluation of MERS-CoV (Jun 7, 2013)                                                                                   Interim guidelines for collection, processing and transport of clinical specimens (Jun 7, 2013)          Interim guidance for preventing MERS-CoV from spreading in homes and communities (Jul 11, 2014)
Interim home care and isolation guidance for MERS-CoV (Jul 11, 2014)
Advanced molecular detection (Jun 4, 2014)
MERS-CoV Images                                                   

European Centre for Disease Prevention and Control (ECDC)

MERS-CoV page
Updated rapid risk assessment (Apr 25, 2014) 
Epidemiologic update
(May 16, 2014)

Public Health England (PHE)

MERS-CoV page
Key facts  (Oct 4, 2013)
Risk assessment (May 2, 2014)
Treatment of MERS-CoV: Decision support tool (Jul 14, 2014)
Infection control advice (Jun 28, 2013)
Primary care algorithm for MERS & avian flu (May 28, 2014)
Algorithm for management of possible cases (Jul 14, 2014)
Algorithm for management of close contacts (May 16, 2014)
Epidemiologic protocols (Nov 11, 2013)

Food and Drug Administration (FDA)

RT-PCR Assay fact sheet for health care professionals (Jun 12, 2014)
RT-PCR assay fact sheet for patients (Jun 12, 2014) 
Emergency use authorization (Jun 10, 2014)

World Organization for Animal Health (OIE)

Questions and answers  (Aug 2014)

Public Health Agency of Canada (PHAC)

Risk assessment (Aug 21, 2014)
Public health notice (Aug 21, 2014)
Travel health notice (Jul 24, 2014)
Infection prevention and control guidance (Oct 4, 2013)
Interim case definition (Sep 23, 2013)
Coronavirus in animals (May 28, 2013)
Case report form (Apr 22, 2013) 

Saudi Arabia Ministry of Health (MOH)

MERS-CoV Page 
Infection prevention and control precautions (May 15, 2013)
Frequently asked questions
Procedures for suspected or confirmed cases 
Media Statements  

Twitter 

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers (@FluTrackers)
Jason Gale (@jwgale)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
Ian M Mackay, PhD (@MackayIM)
Maia Majumder, MPH (@maiamajumder)
NPR Global Health (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

Recent Literature

Abroug F, Slim A, Ouanes-Besbes L, et al. Family cluster of Middle East respiratory syndrome coronavirus infections, Tunisia, 2013. Emerg Infect Dis 2014 (published online Jun 9)

Aburizaiza AS, Mattes FM, Azhar EI, et al. Investigation of anti-MERS-coronavirus antibodies in blood donors and abattoir workers in Jeddah and Makkah, Kingdom of Saudi Arabia, fall 2012. J Infect Dis 2013 (published online Nov 11)

Al-Abdallat MM, Payne DC, Alqasrawi S, et al. Hospital-associated outbreak of Middle East respiratory syndrome coronavirus: a serologic, epidemiologic, and clinical description. Clin Infect Dis 2014 (published online May 14)

Al-Tawfiq JA, Hinedi K, Ghandour J, et al. Middle East respiratory syndrome-coronavirus (MERS-CoV): a case-control study of hospitalized patients. Clin Infect Dis 2014 (published online Apr 9)

Alagaili AN, Briese T, Mishra N, et al. Middle East respiratory syndrome coronavirus infection in dromedary camels in Saudi Arabia. MBio 2014 Feb 25;5(2):e00884-14

Alexandersen S, Kobinger GP, Soule G, et al. Middle East respiratory syndrome coronavirus antibody reactors among camels in Dubai, United Arab Emirates, in 2005. Transbound Emerg Dis 2014 (published online Jan 24)

Almazan F, DeDiego ML, Sola I, et al. Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate. MBio 2013 Sep 10; vol. 4 no. 5 e00650-13

Arabi YM, Afifi AA, Balkhy HH, et al. Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection. Ann Intern Med 2014 (published online Jan 28)

Azhar EI, El-Kafrawy SA, Farraj SA, et al. Evidence for camel-to-human transmission of MERS coronavirus. N Engl J Med 2014 (published online Jun 3)

Azhar EI, Hashem AM, El-Kafrawy SA, et al. Detection of the Middle East respiratory syndrome coronavirus genome in an air sample originating from a camel barn owned by an infected patient. MBio 2014 Jul 22;5(4):e01450-14

Briese T, Mishra N, Jain K, et al. Middle East respiratory syndrome coronavirus quasispecies that include homologues of human isolates revealed through whole-genome analysis and virus cultured from dromedary camels in Saudi Arabia. MBio 2014;5(3):301146-14 (published online Apr 29)

Cauchemez S, Fraser C, Kerkhove MDV, et al. Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility. Lancet Infect Dis 2013 (published online Nov 13)

CDC. First confirmed cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in the United States, updated information on the epidemiology of MERS-CoV infection, and guidance for the public, clinicians, and public health authorities. MMWR 2014 May 14;63(early release):1-6

CDC. Updated information on the epidemiology of Middle East respiratory syndrome coronavirus (MERS-CoV) infection and guidance for the public, clinicians, and public health authorities, 2012-2013. MMWR 2013 Sep 27;62(38):793-6

Chan JFW, Chan KH, Kao RYT, et al. Broad-specturum antivirals for the emerging Middle East respiratory syndrome coronavirus. J Infect 2013 (published online Oct 3)

Chu DKW, Poon LLM, Gomaa MM, et al. MERS coronavirus in dromedary camels, Egypt. Emerg Infect Dis 2014 (published online Feb 27)

Coleman CM, Frieman MB. Emergence of the Middle East respiratory syndrome coronavirus. PLoS Pathog 2013 Sep 5;9(9):e1003595

Corman VM, Ithete NL, Richards LR, et al. Rooting the phylogenetic tree of MERS-coronavirus by characterization of a conspecific virus from an African bat. J Virol 2014 (published online Jul 16)

Corman VM, Jores J, Meyer B, et al. Antibodies against MERS coronavirus in dromedary camels, Kenya, 1992-2013. Emerg Infect Dis 2014 Aug;20(8)

Cotten M, Watson SJ, Kellam P, et al. Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study. Lancet 2013 (published online Sep 20) 

Cotten M, Watson SJ, Zumla AI, et al. Spread, circulation, and evolution of the Middle East respiratory syndrome coronavirus. MBio 2014 Feb 18;5(1):e01062

Cui J, Eden J-S, Holmes EC, et al. Adaptive evolution of bad dipeptidyl peptidase 4 (dpp4): implications for the origin and emergence of Middle East respiratory syndrome coronavirus. Virol J 2013 (published online Oct 10) 

de Wit E, Rasmussen AL, Falzarano D, et al. Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques. Proc Natl Acad Sci 2013 (published online Sep 23)

Doremalen NV, Bushmaker T, Karesh WB, et al. Stability of Middle East respiratory syndrome coronavirus in milk. (Letter) Emerg Infect Dis 2014 (published online Apr 7)

Eckerle I, Corman VM, Muller MA, et al. Replicative capacity of MERS coronavirus in livestock cell lines. Emerg Infect Dis 2013 (published online Dec 18)

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