MERS-CoV

Middle East respiratory syndrome coronavirus

Recent News

Oct 22, 2014

News Scan for Oct 22, 2014

New MERS case in Saudi Arabia
Flu virus mutation
Live-poultry Salmonella outbreak over
Oct 21, 2014

News Scan for Oct 21, 2014

New Saudi MERS illness
More EV-D68 cases
Oct 20, 2014

Turkey has first MERS case; Saudi Arabia acts to stop cluster

Turkey's case involves a man who visited Saudi Arabia, which has a cluster in Taif.

Oct 17, 2014

WHO: Several recent MERS patients drank camel milk

Four recent Saudi case-patients had frequent contact with camels and often had their milk, both of which are considered risk factors for human disease.

Oct 14, 2014

News Scan for Oct 14, 2014

Another MERS case in Saudi Arabia
New EV-D68 test
Chikungunya on Tahiti
Oct 13, 2014

News Scan for Oct 13, 2014

MERS in Qatar, Saudi Arabia
Chikungunya spread continues
Fecal transplant for C diff
H5N2 in Germany
Oct 09, 2014

News Scan for Oct 09, 2014

Costs of foodborne illness
Severe illness with MERS
Haiti cholera lawsuit
Oct 07, 2014

News Scan for Oct 07, 2014

EV-D68 cases top 600
Dengue in India, China
Two MERS cases in Saudi Arabia
Flu ebbs in Southern Hemisphere
Oct 06, 2014

News Scan for Oct 06, 2014

New Saudi MERS cases
Chikungunya numbers rise
Marburg in Uganda
Pakistan polio cases top 200
Oct 02, 2014

WHO: Saudi MERS patient in Austria was sick during travel

Two of the woman's close contacts have respiratory symptoms and are being tested for MERS-CoV.

Resources & Literature

Resources

 

Jump to Recent Literature

 

Last updated Oct 8, 2014

Latest Cases & General Information

Frequently updated case list from FluTrackersTransmission electron micrograph of Middle East Respiratory Syndrome Coronavirus
Disease outbreak news from WHO
Maia Majumder, MPH, MERS resources on Tumblr
Virology Down Under MERS-CoV page
Naming of MERS-CoV from Science (May 6, 2013)
Genetic sequence of MERS-CoV from PHE

Health Agency Documents

World Health Organization (WHO)

MERS-CoV page 
List of latest case updates
Summary updates landing page
Latest risk assessment (Apr 24, 2014)
Frequently asked questions (May 9, 2014)
Interim Case Definitions (Jul 14, 2014)
Guidance on conducting case-control studies (Jul 15, 2014)
Interim surveillance recommendations (Jun 27, 2013)
Interim recommendations for laboratory testing (Sep 16, 2o13)
Seroepidemiological investigation of contacts (Nov 19, 2013)                                                                     Risk factors of infection among health care personnel (Jan 27, 2014)
Guidance for health care professionals (May 6, 2013)
Clinical management (Feb 11, 2013)
Home care for patients with MERS-CoV infection (Aug 8, 2013)
Travel recommendations (Jun 5, 2013)
Travel advice for pilgrims (Jun 3, 2014)
Naming of the novel coronavirus (May 28, 2013)

US Centers for Disease Control and Prevention (CDC)

MERS-CoV page
Press release on first US case
(May 2, 2014)
Press release on clearing of contacts of first 2 US cases (Jun 17, 2014)
Health Alert Network advisory (May 3, 2014)
Frequently asked questions
(Aug 4, 2014)
Case definitions (Jun 25, 2014)
Interim guidance for healthcare professionals (Jul 29, 2014)
Guidance for travelers (May 21, 2014)
Infection prevention and control guidelines (Jul 11, 2014)
Information and guidance for clinicians (Jun 18, 2013)
Guidance on air medical transport for MERS patients (Jul 3, 2014)

Interim guidance for airline crew
(Mar 10, 2014)
Guidelines for evaluation of MERS-CoV (Jun 7, 2013)                                                                                   Interim guidelines for collection, processing and transport of clinical specimens (Jun 7, 2013)          Interim guidance for preventing MERS-CoV from spreading in homes and communities (Jul 11, 2014)
Interim home care and isolation guidance for MERS-CoV (Jul 11, 2014)
Advanced molecular detection (Aug 25, 2014)
MERS-CoV Images                                                   

European Centre for Disease Prevention and Control (ECDC)

MERS-CoV page
Updated rapid risk assessment (Apr 25, 2014) 
Epidemiologic update
(May 16, 2014)

Public Health England (PHE)

MERS-CoV page
Key facts  (Oct 4, 2013)
Risk assessment (May 2, 2014)
Treatment of MERS-CoV: Decision support tool (Jul 14, 2014)
Infection control advice (Jun 28, 2013)
Primary care algorithm for MERS & avian flu (May 28, 2014)
Algorithm for management of possible cases (Jul 14, 2014)
Algorithm for management of close contacts (May 16, 2014)
Epidemiologic protocols (Nov 11, 2013)

Food and Drug Administration (FDA)

RT-PCR Assay fact sheet for health care professionals (Jun 12, 2014)
RT-PCR assay fact sheet for patients (Jun 12, 2014) 
Emergency use authorization (Jun 10, 2014)

World Organization for Animal Health (OIE)

Questions and answers  (Aug 2014)

Public Health Agency of Canada (PHAC)

Risk assessment (Oct 8, 2014)
Public health notice (Oct 1, 2014)
Travel health notice (Jul 24, 2014)
Infection prevention and control guidance (Oct 4, 2013)
Interim case definition (Sep 23, 2013)
Coronavirus in animals (May 28, 2013)
Case report form (Apr 22, 2013) 

Saudi Arabia Ministry of Health (MOH)

MERS-CoV Page 
Infection prevention and control precautions (May 15, 2013)
Frequently asked questions
Procedures for suspected or confirmed cases 
Media Statements  

Twitter 

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers (@FluTrackers)
Jason Gale (@jwgale)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
Ian M Mackay, PhD (@MackayIM)
Maia Majumder, MPH (@maiamajumder)
NPR Global Health (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

Recent Literature

Abroug F, Slim A, Ouanes-Besbes L, et al. Family cluster of Middle East respiratory syndrome coronavirus infections, Tunisia, 2013. Emerg Infect Dis 2014 (published online Jun 9)

Aburizaiza AS, Mattes FM, Azhar EI, et al. Investigation of anti-MERS-coronavirus antibodies in blood donors and abattoir workers in Jeddah and Makkah, Kingdom of Saudi Arabia, fall 2012. J Infect Dis 2013 (published online Nov 11)

Adney DR, van Doremalen N, Brown VR, et al. Replication and shedding of MERS-CoV in upper respiratory tract of inoculated dromedary camels. Emerg Infect Dis 2014 (published online Sep 24)

Al-Abdallat MM, Payne DC, Alqasrawi S, et al. Hospital-associated outbreak of Middle East respiratory syndrome coronavirus: a serologic, epidemiologic, and clinical description. Clin Infect Dis 2014 (published online May 14)

Al-Tawfiq JA, Hinedi K, Ghandour J, et al. Middle East respiratory syndrome-coronavirus (MERS-CoV): a case-control study of hospitalized patients. Clin Infect Dis 2014 (published online Apr 9)

Al-Tawfiq JA, Zumla A, Memish ZA. Travel implications of emerging coronaviruses: SARS and MERS-CoV. Travel Med Infect Dis 2014 Sep-Oct;12(5):422-8

Alagaili AN, Briese T, Mishra N, et al. Middle East respiratory syndrome coronavirus infection in dromedary camels in Saudi Arabia. MBio 2014 Feb 25;5(2):e00884-14

Alexandersen S, Kobinger GP, Soule G, et al. Middle East respiratory syndrome coronavirus antibody reactors among camels in Dubai, United Arab Emirates, in 2005. Transbound Emerg Dis 2014 (published online Jan 24)

Arabi YM, Afifi AA, Balkhy HH, et al. Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infection. Ann Intern Med 2014 (published online Jan 28)

Azhar EI, El-Kafrawy SA, Farraj SA, et al. Evidence for camel-to-human transmission of MERS coronavirus. N Engl J Med 2014 (published online Jun 3)

Azhar EI, Hashem AM, El-Kafrawy SA, et al. Detection of the Middle East respiratory syndrome coronavirus genome in an air sample originating from a camel barn owned by an infected patient. MBio 2014 Jul 22;5(4):e01450-14

Briese T, Mishra N, Jain K, et al. Middle East respiratory syndrome coronavirus quasispecies that include homologues of human isolates revealed through whole-genome analysis and virus cultured from dromedary camels in Saudi Arabia. MBio 2014;5(3):301146-14 (published online Apr 29)

Cauchemez S, Fraser C, Kerkhove MDV, et al. Middle East respiratory syndrome coronavirus: quantification of the extent of the epidemic, surveillance biases, and transmissibility. Lancet Infect Dis 2013 (published online Nov 13)

CDC. First confirmed cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in the United States, updated information on the epidemiology of MERS-CoV infection, and guidance for the public, clinicians, and public health authorities. MMWR 2014 May 14;63(early release):1-6

Chan RWY, Hemida MG, Kayali G, et al. Tropism and replication of Middle East respiratory syndrome coronavirus from dromedary camels in the human respiratory tract: an in-vitro and ex-vivo study. Lancet Respir Med 2014 (published online Aug 29)

Chu DKW, Poon LLM, Gomaa MM, et al. MERS coronavirus in dromedary camels, Egypt. Emerg Infect Dis 2014 (published online Feb 27)

Corman VM, Ithete NL, Richards LR, et al. Rooting the phylogenetic tree of MERS-coronavirus by characterization of a conspecific virus from an African bat. J Virol 2014 (published online Jul 16)

Corman VM, Jores J, Meyer B, et al. Antibodies against MERS coronavirus in dromedary camels, Kenya, 1992-2013. Emerg Infect Dis 2014 Aug;20(8)

Cotten M, Watson SJ, Zumla AI, et al. Spread, circulation, and evolution of the Middle East respiratory syndrome coronavirus. MBio 2014 Feb 18;5(1):e01062

Doremalen NV, Bushmaker T, Karesh WB, et al. Stability of Middle East respiratory syndrome coronavirus in milk. (Letter) Emerg Infect Dis 2014 (published online Apr 7)

Drosten C, Meyer B, Muller MA, et al. Transmission of MERS-coronavirus in household contacts. N Engl J Med 2014 Aug 28;371(9):828-35

Eckerle I, Corman VM, Muller MA, et al. Replicative capacity of MERS coronavirus in livestock cell lines. Emerg Infect Dis 2013 (published online Dec 18)

Falzarano D, de Wit E, Feldmann F, et al. Infection with MERS-CoV causes lethal pneumonia in the common marmoset. PLoS Pathog 2014 Aug 21;10(8):e1004250

Ferguson NM, Kerkhove MDV. Identification of MERS-CoV in dromedary camels. Lancet Infect Dis 2013 (published online Dec 17)

Gardner LM, MacIntyre CR. Unanswered questions about the Middle East respiratory syndrome coronavirus (MERS-CoV). BMC Res Notes 2014 Jun 11;7:358

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