MERS-CoV

Middle East respiratory syndrome coronavirus

Recent News

Feb 05, 2016

News Scan for Feb 05, 2016

Finalized USDA poultry standards
Adult vaccine coverage
First MERS autopsy
Feb 03, 2016

News Scan for Feb 03, 2016

Saudi MERS case
Sierra Leone Ebola update
WHO crisis response critique
Feb 02, 2016

News Scan for Feb 02, 2016

Salmonella tied to supplement
Saudi MERS developments
More Hawaii dengue
Malaria project
Feb 01, 2016

News Scan for Feb 01, 2016

Saudi MERS case
CDC flu advisory
Missing Ebola funds
Jan 29, 2016

News Scan for Jan 29, 2016

MERS vaccine to be tested
GBS and AFP in Wales
TB risk in aircraft
Polio cases in Laos
Jan 27, 2016

News Scan for Jan 27, 2016

New Saudi MERS case
More chikungunya infections
Jan 26, 2016
Camel

WHO Saudi MERS mission finds progress, urges more steps

Also, 5 of 6 recent cases detailed by the WHO involve camel contact.

Jan 25, 2016
Thailand map

Thailand reports imported MERS case; Saudi Arabia notes 2

For the 2nd time in 7 months, Thailand has reported a case in a traveler from Oman.

Jan 22, 2016

News Scan for Jan 22, 2016

Deadly Listeria outbreak
Saudi MERS cases
More Lassa fever in Nigeria
Jan 14, 2016

News Scan for Jan 14, 2016

Two MERS cases in UAE
Italian MCR-1 detection
Polio funds, setback

Resources & Literature

Resources

 

Jump to Recent Literature

 

Last updated Oct 8, 2014

Latest Cases & General Information

Frequently updated case list from FluTrackersTransmission electron micrograph of Middle East Respiratory Syndrome Coronavirus
Disease outbreak news from WHO
Maia Majumder, MPH, MERS resources on Tumblr
Virology Down Under MERS-CoV page
Naming of MERS-CoV from Science (May 6, 2013)
Genetic sequence of MERS-CoV from PHE

Health Agency Documents

World Health Organization (WHO)

MERS-CoV page 
List of latest case updates
Summary updates landing page
Latest risk assessment (Apr 24, 2014)
Frequently asked questions (May 9, 2014)
Interim Case Definitions (Jul 14, 2014)
Guidance on conducting case-control studies (Jul 15, 2014)
Interim surveillance recommendations (Jun 27, 2013)
Interim recommendations for laboratory testing (Sep 16, 2o13)
Seroepidemiological investigation of contacts (Nov 19, 2013)                                                                     Risk factors of infection among health care personnel (Jan 27, 2014)
Guidance for health care professionals (May 6, 2013)
Clinical management (Feb 11, 2013)
Home care for patients with MERS-CoV infection (Aug 8, 2013)
Travel recommendations (Jun 5, 2013)
Travel advice for pilgrims (Jun 3, 2014)
Naming of the novel coronavirus (May 28, 2013)

US Centers for Disease Control and Prevention (CDC)

MERS-CoV page
Press release on first US case
(May 2, 2014)
Press release on clearing of contacts of first 2 US cases (Jun 17, 2014)
Health Alert Network advisory (May 3, 2014)
Frequently asked questions
(Aug 4, 2014)
Case definitions (Jun 25, 2014)
Interim guidance for healthcare professionals (Jul 29, 2014)
Guidance for travelers (May 21, 2014)
Infection prevention and control guidelines (Jul 11, 2014)
Information and guidance for clinicians (Jun 18, 2013)
Guidance on air medical transport for MERS patients (Jul 3, 2014)

Interim guidance for airline crew
(Mar 10, 2014)
Guidelines for evaluation of MERS-CoV (Jun 7, 2013)                                                                                   Interim guidelines for collection, processing and transport of clinical specimens (Jun 7, 2013)          Interim guidance for preventing MERS-CoV from spreading in homes and communities (Jul 11, 2014)
Interim home care and isolation guidance for MERS-CoV (Jul 11, 2014)
Advanced molecular detection (Aug 25, 2014)
MERS-CoV Images                                                   

European Centre for Disease Prevention and Control (ECDC)

MERS-CoV page
Updated rapid risk assessment (Apr 25, 2014) 
Epidemiologic update
(May 16, 2014)

Public Health England (PHE)

MERS-CoV page
Key facts  (Oct 4, 2013)
Risk assessment (May 2, 2014)
Treatment of MERS-CoV: Decision support tool (Jul 14, 2014)
Infection control advice (Jun 28, 2013)
Primary care algorithm for MERS & avian flu (May 28, 2014)
Algorithm for management of possible cases (Jul 14, 2014)
Algorithm for management of close contacts (May 16, 2014)
Epidemiologic protocols (Nov 11, 2013)

Food and Drug Administration (FDA)

RT-PCR Assay fact sheet for health care professionals (Jun 12, 2014)
RT-PCR assay fact sheet for patients (Jun 12, 2014) 
Emergency use authorization (Jun 10, 2014)

World Organization for Animal Health (OIE)

Questions and answers  (Aug 2014)

Public Health Agency of Canada (PHAC)

Risk assessment (Oct 8, 2014)
Public health notice (Oct 1, 2014)
Travel health notice (Jul 24, 2014)
Infection prevention and control guidance (Oct 4, 2013)
Interim case definition (Sep 23, 2013)
Coronavirus in animals (May 28, 2013)
Case report form (Apr 22, 2013) 

Saudi Arabia Ministry of Health (MOH)

MERS-CoV Page 
Infection prevention and control precautions (May 15, 2013)
Frequently asked questions
Procedures for suspected or confirmed cases 
Media Statements  

Twitter 

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers (@FluTrackers)
Jason Gale (@jwgale)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
Ian M Mackay, PhD (@MackayIM)
Maia Majumder, MPH (@maiamajumder)
NPR Global Health (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

Recent Literature

Al Hammadi ZM, Chu DK, Eltahir YM, et al. Asymptomatic MERS-CoV infection in humans possibly linked to infected camels imported from Oman to United Arab Emirates, May 2015. Emerg Infect Dis 2015 Dec;21(12)

Assiri A, Abedi GR, Saeed AAB, et al. Multifacility outbreak of Middle East respiratory syndrome in Taif, Saudi Arabia. Emerg Infect Dis 2015 (published online Nov 2)

Breakwell L, Pringle K, Chea N, et al. Lack of transmission among close contacts of patient with imported case of Middle East respiratory syndrome into the United States, 2014. Emerg Infect Dis 2015 (published online Apr 8)

Chan JFW, Yao Y, Yeung ML, et al. Treatment with lopinavir/ritonavir or interferon-beta-1b improves outcome of MERS-CoV infection in a non-human primate model of common marmoset.  J Infect Dis 2015 (published online Jul 21)

Chan SMS, Damdinjav B, Perera RAPM, et al. Absence of MERS-coronavirus in Bactrian camels, southern Mongolia, November 2014. (Letter) Emerg Infect Dis 2015 (published online Mar 4)

Chowell G, Abdirizak F, Lee S, et al. Transmission characteristics of MERS and SARS in the healthcare setting: a comparative study. BMC Medicine 2015 Sep 3;13:210

Chu DK, Oladipo JO, Perera RA, et al. Middle East respiratory syndrome coronavirus (MERS-COV) in dromedary camels in Nigeria, 2015. Euro Surveill 2015 Dec 10;20(49):pii=30086

Chu J, Zhou J, Wong BH, et al. Middle East respiratory syndrome coronavirus efficiently infects human primary T lymphocytes and activates the extrinsic and intrinsic apoptosis pathways. J Infect Dis 2015 (published online Jul 22)

Corman VM, Albarrak AM, Omrani AS, et al. Viral shedding and antibody response in 37 patients with MERS-coronavirus infection. Clin Infect Dis 2015 (published online Nov 12)

Corti D, Zhao J, Pedotti M, et al. Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus. Proc Natl Acad Sci 2015 (published online Jul 27)

Cowling BJ, Park M, Fang V, et al. Preliminary epidemiological assessment of MERS-CoV outbreak in South Korea, May to June 2015. Euro Surveill 2015 Jun 25;20(25):pii=21163

Deem SL, Fevre EM, Kinnaird M, et al. Serological evidence of MERS-CoV antibodies in dromedary camels (Camelus dromedaries) in Laikipia County, Kenya. PLoS One 2015 Oct 16;10(10):e0140125

Fabgo SF, Skakni L, Chu DKW, et al. Molecular epidemiology of hospital outbreak of Middle East respiratory syndrome, Riyadh, Saudi Arabia, 2014. Emerg Infect Dis 2015 (published online Jul 20)

Feikin DR, Alraddadi B, Qutub M, et al. Association of higher MERS-CoV virus load with severe disease and death, Saudi Arabia, 2014. Emerg Infect Dis 2015 (published online Jul 24)

Gostin LO, Lucey D. Middle East respiratory syndrome: a global health challenge. (Commentary) JAMA 2015 (published online Jun 17)

Gutierrez C, Tejedor-Junco MT, Gonzalez M, et al. Presence of antibodies but no evidence for circulation of MERS-CoV in dromedaries on the Canary Islands, 2015. Euro Surveill 2015 Sep 17;20(37):pii=30019

Haagmans BL, van den Brand JMA, Raj VS, et al. An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels. Science 2015 (published online Dec 17)

Johnson RF, Bagci U, Keith L, et al. 3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012. Virology 2016 (published online Jan 30)

 

Johnson RF, Via LE, Kumar MR, et al. Intratracheal exposure to common marmosets to MERS-CoV Jordan-n3/3012 or MERS-CoV EMC/2012 isolates does not result in lethal disease. Virology 2015 (published online Sep 3)


Khalafalla AI, Lu X, Al-Mubarak AIA, et al. MERS-CoV in upper respiratory tract and lungs of dromedary camels, Saudi Arabia, 2013-2014. Emerg Infect Dis 2015 (published online Apr 22)

Lee SS, Wong NS. Probable transmission chains of Middle East respiratory syndrome coronavirus and the multiple generations of secondary infection in South Korea. Int J Infect Dis 2015 Sep;38(suppl C): 65-7

Li K, Wohlford-Lenane C, Perlman S, et al. Middle East respiratory syndrome coronavirus cause multiple organ damage and lethal disease in mice transgenic for human dipeptidyl peptidase 4. J Infect Dis 2015 (published online Oct 20)

Majumder MS, Kluberg SA, Mekaru SR, et al. Mortality risk factors for Middle East respiratory syndrome outbreak, South Korea 2015. Emerg Infect Dis 2015 (published online Aug 19)

Memish ZA, Al-Tawfiq JA, Alhakeem RF, et al. Middle East respiratory syndrome coronavirus (MERS-CoV): a cluster analysis with implications for global management of suspected cases. Travel Med Infect Dis 2015 (published online Jul 14)

Miguel E, Perera RAPM, Baubekova A, et al. Absence of Middle East respiratory syndrome coronavirus in camelids, Kazakhstan, 2015. (Letter) Emerg Infect Dis 2015 (published online Nov 25)

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