MERS-CoV

Middle East respiratory syndrome coronavirus

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Recent News

Oct 14, 2013

WHO confirms two more Saudi MERS cases

Robert Roos | News Editor | CIDRAP News
 |
Oct 14, 2013

As the Hajj starts, the WHO confirms two previously reported Saudi MERS cases, both fatal.

Oct 10, 2013

Survey: MERS advice for high-risk Hajj pilgrims often ignored

Lisa Schnirring | Staff Writer | CIDRAP News
 |
Oct 10, 2013

Pre-Hajj survey finds that at-risk French pilgrims aren't cancelling plans because of MERS.

Oct 04, 2013

WHO confirms 6 MERS cases in Saudi Arabia

Robert Roos | News Editor | CIDRAP News
 |
Oct 04, 2013

The cases, apparently previously reported by Saudi Arabia, raise the global count to 136, with 58 deaths.

Oct 03, 2013

News Scan for Oct 03, 2013

Potential MERS treatment
Fecal transplant via pill
FSMA rules wrangling
Malaria in London
Oct 01, 2013

News Scan for Oct 01, 2013

More Saudi MERS cases
Boston BSL-4 lab clears hurdle
Colorado TB investigation
Hepatitis C screening
Polio in South Sudan
Oct 01, 2013

Fed shutdown affects disease detection, food safety

Lisa Schnirring and Robert Roos | Staff Writers | CIDRAP News
 |
Oct 01, 2013

Response to seasonal flu, H7N9, MERS, and other threats could be markedly diminished.

Sep 30, 2013

Saudis report more MERS-CoV cases; serologic study draws blank

Robert Roos | News Editor | CIDRAP News
 |
Sep 30, 2013

Saudi Arabia reports three more MERS cases, and a serologic study finds no evidence of exposure.

Sep 27, 2013

Reports detail changing pattern of MERS-CoV cases

Robert Roos | News Editor | CIDRAP News
 |
Sep 27, 2013

Cases in recent months show steep declines in the percent of severe and fatal cases.

Sep 25, 2013

WHO panel says MERS still not an emergency

Robert Roos | News Editor | CIDRAP News
 |
Sep 25, 2013

Experts today reaffirmed their earlier finding that MERS is not a global health emergency.

Sep 24, 2013

News Scan for Sep 24, 2013

MERS-CoV research wanted
Hepatitis A berry outbreak
H5N1 outbreaks in Nepal
Land use and disease
All MERS-CoV News

Resources & Literature

Resources: 

 

Jump to Recent Literature

Latest Case Information

Frequently updated case list from FluTrackersTransmission electron micrograph of Middle East Respiratory Syndrome Coronavirus
Case table and other info from Flu Wiki
Disease outbreak news from WHO
Global case map from California Department of Public Health (Jul 23)
Global overview of MERS-CoV slides from WHO (May 23)
Naming of MERS-CoV from Science (May 6)
Genetic sequence of MERS-CoV from PHE
Healthmap.org (click on Coronavirus Surveillance tab at bottom)
Graphs, charts, maps, and other info from Virology Down Under
Latest news from ABC News

Health Agency Documents

World Health Organization (WHO)

MERS-CoV page
Frequently asked questions (Aug 9)
Home care for patients with MERS-CoV infection (Aug 8)
Latest case update (Jul 13)
Interim Case Definitions (Jul 3)
Interim surveillance recommendations (Jun 27)
Interim recommendations for laboratory testing (Sep 16)                                                                          Summary and literature update (Jun 20)
Travel recommendations (Jun 5)
Naming of the novel coronavirus (May 28)
Guidance for health care professionals (May 6)
Clinical management

US Centers for Disease Control and Prevention (CDC)

MERS-CoV page 
MERS-CoV overview (Aug 14)
Case definitions (Aug 19)
Interim guidance for healthcare professionals (Aug 19)
Guidance for travelers (Jul 26)
Infection prevention and control guidelines (Jul 10)
Information and guidance for clinicians (Jun 13)
Interim guidance for airline crew (Jun 10)
Guidelines for evaluation of MERS-CoV (Jun 7)                                                                                           Interim guidelines for collection, processing and transport of clinical specimens (Jun 7)                        Interim guidance for preventing MERS-CoV from spreading in homes and communities (Sep 26) Interim home care and isolation guidance for MERS-CoV (Sep 25)                                                           MERS-CoV Images                                                  

European Centre for Disease Prevention and Control (ECDC)

MERS-CoV page
Updated Rapid risk assessment (Sep 24)
Epidemiological update (Jul 5)
Confirmed case count table (Jun 3)

Public Health England (PHE)

MERS-CoV page
Treatment of MERS-CoV: Decision support tool (Jul 29)
Infection control advice (Jun 28)
Algorithm for management of possible cases (Jun 26)
Key facts  (Jun 19)
Algorithm for management of close contacts (Jun 6)
Information for healthcare professionals (Mar 28)
Risk assessment (Jan 18)
Epidemiological protocols (Nov 30, 2012)

Food and Drug Administration (FDA)

RT-PCR Assay fact sheet for health care professionals (May 30)
RT-PCR assay fact sheet for patients (May 30) 
Emergency use authorization (May 29)

World Organisation for Animal Health (OIE)

Questions and answers 

Public Health Agency of Canada (PHAC)

Risk assessment (Aug 27)
Public health notice (Aug 27)
Travel health notice (Aug 6)
Frequently asked questions (Jun 17)
Infection prevention and control guidance (May 31)
Interim case definition (May 28)
Coronavirus in animals (May 28)
Case report form (Apr 22) 

Saudi Arabia Ministry of Health (MOH)

MERS-CoV Page 
Infection prevention and control precautions (May 15)
Frequently asked questions
Procedures for suspected or confirmed cases 
Media Statements  

Twitter 

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers.com (@FluTrackers)
Jason Gale (@jwgale)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
nprGlobalHealth (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

Recent Literature

 Almazan F, DeDiego ML, Sola I, et al. Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate. MBio 2013 Sep 10; vol. 4 no. 5 e00650-13

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MBio

Annan A, Baldwin HJ, Corman VM, et al. Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe. Emerg Infect Dis 2013 Mar;19(3):456-9

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Emerg Infect Dis

Anthony S, Ojeda-Flores R, Rico-Chavez O, et al. Coronaviruses in bats from Mexico. J Gen Virol 2013 (published online Jan 30)

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J Gen Virol

Assiri A, Al-Tawfig JA, Al-Rabeeah AA, et al. Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study. Lancet Infect Dis 2013 Sep;13(9):752-61

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Lancet Infect Dis

Assiri A, McGeer A, Perl RM, et al. Hospital outbreak of Middle East respiratory syndrome coronavirus. N Engl J Med 2013 Aug 1;369:407-16

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N Engl J Med

Breban R, Riou J, Fontanet A. Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk. Lancet 2013 Aug 24;382(9893):694-9

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Lancet

Cauchemez S, Van Kerkhove MD, Riley S, et al. Transmission scenarios for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and how to tell them apart. Euro Surveill 2013 Jun 13;18(24):pii=20503

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Euro Surveill

CDC. Update: severe respiratory illness associated with a novel coronavirus--worldwide, 2012-2013. MMWR 2013 Mar 15;62(10):194

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MMWR

CDC. Update: Severe respiratory illness associated with Middle East respiratory syndrome coronavirus (MERS-CoV)—worldwide, 2012-2013. MMWR 2013 Jun 7;62(Early release):1-4

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MMWR

CDC. Updated information on the epidemiology of Middle East respiratory syndrome coronavirus (MERS-CoV) infection and guidance for the public, clinicians, and public health authorities, 2012-2013. MMWR 2013 Sep 27;62(38):793-6

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MMWR

Chan JFW, Chan KH, Choi GKY, et al. Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: implications on disease pathogenesis and clinical manifestation. J Infect Dis 2013 Jun 1;207(11):1743-52

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J Infect Dis

Chan JFW, Chan KH, Kao RYT, et al. Broad-specturum antivirals for the emerging Middle East respiratory syndrome coronavirus. J Infect 2013 (published online Oct 3)

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J Infect Dis

Chan JFW, Li KSM, To KKW, et al. Is the discovery of the novel human betacoronavirus 2c EMC/2012 the beginning of another SARS-like pandemic? J Infect 2012 Dec;65(6):477-89

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J Infect Dis

Chan KH, Chan JFW, Tse H, et al. Cross-reactive antibodies in convalescent SARS patients' sera against the emerging novel human coronavirus EMC (2012) by both immunofluorescent and neutralizing antibody tests. J Infect 2013 Aug;67(2):130-40

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J Infect

Coleman CM, Frieman MB. Emergence of the Middle East respiratory syndrome coronavirus. PLoS Pathog 2013 Sep 5;9(9):e1003595

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PLoS Pathog

Cotten M, Watson SJ, Kellam P, et al. Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study. Lancet 2013 (published online Sep 20) 

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Lancet

Cotton M, Lam TT, Watson SJ, et al. Full-genome deep sequencing and phylogenetic analysis of novel human betacoronavirus. Emerg Infect Dis 2013 May;19(5):736-42

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Emerg Infect Dis

Cui J, Eden J-S, Holmes EC, et al. Adaptive evolution of bad dipeptidyl peptidase 4 (dpp4): implications for the origin and emergence of Middle East respiratory syndrome coronavirus. Virol J 2013 (published online Oct 10) 

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Virol J

de Groot RJ, Baker SC, Baric RS, et al. Middle East Respiratory Syndrome Coronavirus (MERS-CoV); announcement of the coronavirus study group. J Virol 2013 (published online May 15)

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J Virol

de Wit E, Rasmussen AL, Falzarano D, et al. Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques. Proc Natl Acad Sci 2013 (published online Sep 23)

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Proc Natl Acad Sci

Drosten C, Seilmaier M, Corman VM, et al. Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infection. Lancet Infect Dis 2013 Sep;13(9):745-51

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Lancet Infect Dis

Du L, Zhao G, Kou Z, et al. Identification of receptor-binding domain in S protein of the novel human coronavirus MERS-CoV as an essential target for vaccine development. J Virol 2013 (published online Jul 3)

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J Virol

Falzarano D, de Wit E, Rasmussen AL, et al. Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV–infected rhesus macaques. (Letter) Nat Med 2013 (published online Sep 8)

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Nat Med

Gautret P, Benkouiten S, Salaheddine I, et al. Hajj pilgrims' knowledge about Middle East respiratory syndrome coronavirus, August to September 2013. Euro Surveill 2013 Oct 10; 18(41):pii=206604

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Euro Surveill

Gierer, S, Hofmann-Winkler H, Albuali WH, et al. Lack of MERS coronavirus neutralizing antibodies in humans, Eastern Province, Saudi Arabia. Emerg Infect Dis 2013 (published online Sep 27)

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Emerg Infect Dis
More Literature
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