MERS-CoV

Middle East respiratory syndrome coronavirus

Recent News

Aug 26, 2016
Bangkok airport

Imported MERS case in Thailand is country's third

In another MERS development, Saudi Arabia's health ministry announced an illness in a man from Taif whose exposure is under investigation.

Aug 25, 2016

News Scan for Aug 25, 2016

Estimates of severe MERS
New FSMA guidance
TB rates in India
Intussusception and rotavirus vaccine
Aug 23, 2016
baby goat

More MERS in Saudi Arabia as antibody therapies get funding

In a related development, a new study suggests goats, sheep, and horses aren't likely to pass MERS-CoV to humans.

Aug 18, 2016

News Scan for Aug 18, 2016

Saudi MERS case
Burden of bloodstream infections
UN Haiti cholera shift
Contact lens infections
Aug 16, 2016

News Scan for Aug 16, 2016

Malaria may boost Ebola survival
Scallop hepatitis A source
Inhaled vs injectable flu vaccine
Camels and human cold virus
Venezuela malaria spike
Aug 11, 2016

News Scan for Aug 11, 2016

Experimental MERS drug
Nigerian polio cases
More avian flu in France
New TB guidelines
Plague in Zambia
Aug 08, 2016

News Scan for Aug 08, 2016

H3N2v cases in US
Yellow fever vaccine update
Saudi Arabia MERS case
Anthrax vaccine developments
Measles in Myanmar
AI in Ghana and Denmark
Polio eradication
Aug 04, 2016

News Scan for Aug 04, 2016

Saudi MERS case
New US lab safety head
H5N1 in Nigeria
Monitoring H5N6 in China
Aug 02, 2016

News Scan for Aug 02, 2016

Plasmids and antibiotic resistance
Saudi MERS cases
More chikungunya
Anthrax vaccine candidate
Jul 29, 2016

News Scan for Jul 29, 2016

MERS reappears in Saudi Arabia
Yellow fever slows
Anthrax in Siberia
Statins and flu vaccine protection

Resources & Literature

Resources

 

Jump to Recent Literature

 

Last updated Oct 8, 2014

Latest Cases & General Information

Frequently updated case list from FluTrackersTransmission electron micrograph of Middle East Respiratory Syndrome Coronavirus
Disease outbreak news from WHO
Maia Majumder, MPH, MERS resources on Tumblr
Virology Down Under MERS-CoV page
Naming of MERS-CoV from Science (May 6, 2013)
Genetic sequence of MERS-CoV from PHE

Health Agency Documents

World Health Organization (WHO)

MERS-CoV page 
List of latest case updates
Summary updates landing page
Latest risk assessment (Apr 24, 2014)
Frequently asked questions (May 9, 2014)
Interim Case Definitions (Jul 14, 2014)
Guidance on conducting case-control studies (Jul 15, 2014)
Interim surveillance recommendations (Jun 27, 2013)
Interim recommendations for laboratory testing (Sep 16, 2o13)
Seroepidemiological investigation of contacts (Nov 19, 2013)                                                                     Risk factors of infection among health care personnel (Jan 27, 2014)
Guidance for health care professionals (May 6, 2013)
Clinical management (Feb 11, 2013)
Home care for patients with MERS-CoV infection (Aug 8, 2013)
Travel recommendations (Jun 5, 2013)
Travel advice for pilgrims (Jun 3, 2014)
Naming of the novel coronavirus (May 28, 2013)

US Centers for Disease Control and Prevention (CDC)

MERS-CoV page
Press release on first US case
(May 2, 2014)
Press release on clearing of contacts of first 2 US cases (Jun 17, 2014)
Health Alert Network advisory (May 3, 2014)
Frequently asked questions
(Aug 4, 2014)
Case definitions (Jun 25, 2014)
Interim guidance for healthcare professionals (Jul 29, 2014)
Guidance for travelers (May 21, 2014)
Infection prevention and control guidelines (Jul 11, 2014)
Information and guidance for clinicians (Jun 18, 2013)
Guidance on air medical transport for MERS patients (Jul 3, 2014)

Interim guidance for airline crew
(Mar 10, 2014)
Guidelines for evaluation of MERS-CoV (Jun 7, 2013)                                                                                   Interim guidelines for collection, processing and transport of clinical specimens (Jun 7, 2013)          Interim guidance for preventing MERS-CoV from spreading in homes and communities (Jul 11, 2014)
Interim home care and isolation guidance for MERS-CoV (Jul 11, 2014)
Advanced molecular detection (Aug 25, 2014)
MERS-CoV Images                                                   

European Centre for Disease Prevention and Control (ECDC)

MERS-CoV page
Updated rapid risk assessment (Apr 25, 2014) 
Epidemiologic update
(May 16, 2014)

Public Health England (PHE)

MERS-CoV page
Key facts  (Oct 4, 2013)
Risk assessment (May 2, 2014)
Treatment of MERS-CoV: Decision support tool (Jul 14, 2014)
Infection control advice (Jun 28, 2013)
Primary care algorithm for MERS & avian flu (May 28, 2014)
Algorithm for management of possible cases (Jul 14, 2014)
Algorithm for management of close contacts (May 16, 2014)
Epidemiologic protocols (Nov 11, 2013)

Food and Drug Administration (FDA)

RT-PCR Assay fact sheet for health care professionals (Jun 12, 2014)
RT-PCR assay fact sheet for patients (Jun 12, 2014) 
Emergency use authorization (Jun 10, 2014)

World Organization for Animal Health (OIE)

Questions and answers  (Aug 2014)

Public Health Agency of Canada (PHAC)

Risk assessment (Oct 8, 2014)
Public health notice (Oct 1, 2014)
Travel health notice (Jul 24, 2014)
Infection prevention and control guidance (Oct 4, 2013)
Interim case definition (Sep 23, 2013)
Coronavirus in animals (May 28, 2013)
Case report form (Apr 22, 2013) 

Saudi Arabia Ministry of Health (MOH)

MERS-CoV Page 
Infection prevention and control precautions (May 15, 2013)
Frequently asked questions
Procedures for suspected or confirmed cases 
Media Statements  

Twitter 

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers (@FluTrackers)
Jason Gale (@jwgale)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
Ian M Mackay, PhD (@MackayIM)
Maia Majumder, MPH (@maiamajumder)
NPR Global Health (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

Recent Literature

Adney DR, Bielefeldt-Ohmann H, Hartwig AE, et al. Infection, replication, and transmission of Middle East respiratory syndrome coronavirus in alpacas. Emerg Infect Dis 2016 Jun;22(6):1031-7

Adney DR, Brown VR, Porter SM, et al. Inoculation of goats, sheep, and horses with MERS-CoV does not result in productive viral shedding. Viruses 2016 Aug 19;8(8):230

Al Hosani FL, Pringle K, Al Mulla M, et al. Response to emergence of Middle East respiratory syndrome coronavirus, Abu Dhabi, United Arab

Alsahafi AJ, Cheng AC. The epidemiology of Middle East respiratory syndrome (MERS) coronavirus in the Kingdom of Saudi Arabia, 2012-2015. Int J Infect Dis 2016 (published online Feb 10)

Alshukairi AN, Khalid I, Ahmed WA, et al. Antibody response and disease severity in healthcare worker MERS survivors. Emerg Infect Dis 2016 (published online Apr 27)

Arabi Y, Hajeer AH, Luke T, et al. Feasibility of using convalescent plasma immunotherapy for MERS-CoV infection, Saudi Arabia. Emerg Infect Dis 2016 (published online Jul 20)

Arwady MA, Alraddadi B, Basler C, et al. Middle East respiratory syndrome coronavirus transmission in extended family, Saudi Arabia, 2014. Emerg Infect Dis 2016 (published online Jul 15)

Arwady MA, Alraddadi B, Basler C, et al. Middle East respiratory syndrome coronavirus transmission in extended family, Saudi Arabia, 2014. Emerg Infect Dis 2016 (published online May 18)

Assiri A, Abedi GR, Almasry M, et al. Middle East respiratory syndrome coronavirus infection during pregnancy: a report of 5 cases from Saudi Arabia. Clin Infect Dis 2016 (published online Jun 28)

Assiri A, Abedi GR, Saeed AAB, et al. Multifacility outbreak of Middle East respiratory syndrome in Taif, Saudi Arabia. Emerg Infect Dis 2015 (published online Nov 2)

Assiri AM, Midgley CM, Abedi GR, et al. Epidemiology of a novel recombinant MERS-CoV in humans in Saudi Arabia. J Infect Dis 2016 (published online Jun 14)

Atabani, SF, Wilson S, Overton-Lewis C, et al. Active screening and surveillance in the United Kingdom for Middle East respiratory syndrome coronavirus in returning travelers and pilgrims from the Middle East — a prospective descriptive study for the period 2013-2015. Int J Infect Dis 2016 (published online Apr 23)

Badawi A, Ryoo SG. Prevalence of comorbidities in the Middle East respiratory syndrome coronavirus (MERS-CoV): a systematic review and meta-analysis. Int J Infect Dis 2016 (published online Jun 21)

Balkhy HH, Alenazi TH, Alshamrani MM, et al. Nosocomial outbreak of Middle East respiratory syndrome in a large tertiary care hospital — Riyadh, Saudi Arabia, 2015. (Notes from the field) MMWR 2016 Feb 19;65(6):163-4

Butt TS, Koutlakis-Barron I, AlJumaah S, et al. Infection control and prevention practices implemented to reduce transmission risk of Middle East respiratory syndrome-coronavirus in a tertiary care institution in Saudi Arabia. Am J Infect Control 2016 (published online Feb 25)

Cauchemez S, Nouvellet P, Cori A, et al. Unraveling the drivers of MERS-CoV transmission. Proc Natl Acad Sci USA 2016 (published online Jul 25)

Cho SY, Kang JM, Ha YE, et al. MERS-CoV outbreak following a single patient exposure in an emergency room in South Korea: an epidemiological outbreak study. Lancet 2016 (published online Jul 8)

Chowell G, Abdirizak F, Lee S, et al. Transmission characteristics of MERS and SARS in the healthcare setting: a comparative study. BMC Medicine 2015 Sep 3;13:210

Chu DK, Oladipo JO, Perera RA, et al. Middle East respiratory syndrome coronavirus (MERS-COV) in dromedary camels in Nigeria, 2015. Euro Surveill 2015 Dec 10;20(49):pii=30086

Corman VM, Albarrak AM, Omrani AS, et al. Viral shedding and antibody response in 37 patients with MERS-coronavirus infection. Clin Infect Dis 2015 (published online Nov 12)

Corman VM, Eckerle I, Memish ZA, et al. Link of a ubiquitous human coronavirus to dromedary camels. Proc Natl Acad Sci USA (published online Aug 15)

Crameri G, Durr PA, Klein R, et al. Experimental infection and response to rechallenge of alpacas with Middle East respiratory syndrome coronavirus. Emerg Infect Dis 2016 (published online Mar 3)

Deem SL, Fevre EM, Kinnaird M, et al. Serological evidence of MERS-CoV antibodies in dromedary camels (Camelus dromedaries) in Laikipia County, Kenya. PLoS One 2015 Oct 16;10(10):e0140125

Excler JL, Delvecchio CJ, Wiley RE, et al. Toward developing a preventive MERS-CoV vaccine — report from a workshop organized by the Saudi Arabia Ministry of Health and the International Vaccine Institute, Riyadh, Saudi Arabia, November 14-15, 2015. Emerg Infect Dis 2016 (published online Jun 24)

Gutierrez C, Tejedor-Junco MT, Gonzalez M, et al. Presence of antibodies but no evidence for circulation of MERS-CoV in dromedaries on the Canary Islands, 2015. Euro Surveill 2015 Sep 17;20(37):pii=30019

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