MERS-CoV

Middle East respiratory syndrome coronavirus

Recent News

Jul 25, 2016

News Scan for Jul 25, 2016

Saudi MERS update
Ebola vaccine, viral shedding
New chikungunya cases
Jul 22, 2016

News Scan for Jul 22, 2016

Yellow fever decline in Angola
New Saudi MERS case
Salmonella-related meat recall
Jul 20, 2016
Drawing blood

Fatal MERS in Najran as study pans convalescent plasma

Only 2.7% of 443 samples from recovered patients, health workers, and others had high enough antibody levels.

Jul 18, 2016

News Scan for Jul 18, 2016

Zika pregnancy lab findings
MERS family cluster probe
Ebola vaccine developments
HPV vaccine safety
Jul 14, 2016

News Scan for Jul 14, 2016

Saudi MERS case
Southern Hemisphere flu rise
Resistant fungal infections
HAIs: Melioidosis, mycobacteria
EV-D68 and flaccid myelitis
Jul 11, 2016
Two emergency room beds

Patient proximity key in Korean MERS super-spreader event

In findings that could help other hospitals, patients with the highest risk shared the emergency room.

Jul 08, 2016
Camels

Two new Saudi MERS cases noted as experts air road map

Neither new case is linked to a Riyadh outbreak, and experts describe priorities for MERS-CoV research and development.

Jul 07, 2016

News Scan for Jul 07, 2016

MERS developments
H3N2v susceptibility in kids
Viral vs bacterial infection test
Hepatitis death rise
Jul 05, 2016

News Scan for Jul 05, 2016

Ebola survivor drug study
MERS linked to camels
Reduced antibiotics
HPV and cervical abnormalities
Jun 30, 2016

News Scan for Jun 30, 2016

More yellow fever
Saudi MERS cases
New chikungunya cases
FDA on raw dough
H5N1 in Ghana
Hand sanitizer rule

Resources & Literature

Resources

 

Jump to Recent Literature

 

Last updated Oct 8, 2014

Latest Cases & General Information

Frequently updated case list from FluTrackersTransmission electron micrograph of Middle East Respiratory Syndrome Coronavirus
Disease outbreak news from WHO
Maia Majumder, MPH, MERS resources on Tumblr
Virology Down Under MERS-CoV page
Naming of MERS-CoV from Science (May 6, 2013)
Genetic sequence of MERS-CoV from PHE

Health Agency Documents

World Health Organization (WHO)

MERS-CoV page 
List of latest case updates
Summary updates landing page
Latest risk assessment (Apr 24, 2014)
Frequently asked questions (May 9, 2014)
Interim Case Definitions (Jul 14, 2014)
Guidance on conducting case-control studies (Jul 15, 2014)
Interim surveillance recommendations (Jun 27, 2013)
Interim recommendations for laboratory testing (Sep 16, 2o13)
Seroepidemiological investigation of contacts (Nov 19, 2013)                                                                     Risk factors of infection among health care personnel (Jan 27, 2014)
Guidance for health care professionals (May 6, 2013)
Clinical management (Feb 11, 2013)
Home care for patients with MERS-CoV infection (Aug 8, 2013)
Travel recommendations (Jun 5, 2013)
Travel advice for pilgrims (Jun 3, 2014)
Naming of the novel coronavirus (May 28, 2013)

US Centers for Disease Control and Prevention (CDC)

MERS-CoV page
Press release on first US case
(May 2, 2014)
Press release on clearing of contacts of first 2 US cases (Jun 17, 2014)
Health Alert Network advisory (May 3, 2014)
Frequently asked questions
(Aug 4, 2014)
Case definitions (Jun 25, 2014)
Interim guidance for healthcare professionals (Jul 29, 2014)
Guidance for travelers (May 21, 2014)
Infection prevention and control guidelines (Jul 11, 2014)
Information and guidance for clinicians (Jun 18, 2013)
Guidance on air medical transport for MERS patients (Jul 3, 2014)

Interim guidance for airline crew
(Mar 10, 2014)
Guidelines for evaluation of MERS-CoV (Jun 7, 2013)                                                                                   Interim guidelines for collection, processing and transport of clinical specimens (Jun 7, 2013)          Interim guidance for preventing MERS-CoV from spreading in homes and communities (Jul 11, 2014)
Interim home care and isolation guidance for MERS-CoV (Jul 11, 2014)
Advanced molecular detection (Aug 25, 2014)
MERS-CoV Images                                                   

European Centre for Disease Prevention and Control (ECDC)

MERS-CoV page
Updated rapid risk assessment (Apr 25, 2014) 
Epidemiologic update
(May 16, 2014)

Public Health England (PHE)

MERS-CoV page
Key facts  (Oct 4, 2013)
Risk assessment (May 2, 2014)
Treatment of MERS-CoV: Decision support tool (Jul 14, 2014)
Infection control advice (Jun 28, 2013)
Primary care algorithm for MERS & avian flu (May 28, 2014)
Algorithm for management of possible cases (Jul 14, 2014)
Algorithm for management of close contacts (May 16, 2014)
Epidemiologic protocols (Nov 11, 2013)

Food and Drug Administration (FDA)

RT-PCR Assay fact sheet for health care professionals (Jun 12, 2014)
RT-PCR assay fact sheet for patients (Jun 12, 2014) 
Emergency use authorization (Jun 10, 2014)

World Organization for Animal Health (OIE)

Questions and answers  (Aug 2014)

Public Health Agency of Canada (PHAC)

Risk assessment (Oct 8, 2014)
Public health notice (Oct 1, 2014)
Travel health notice (Jul 24, 2014)
Infection prevention and control guidance (Oct 4, 2013)
Interim case definition (Sep 23, 2013)
Coronavirus in animals (May 28, 2013)
Case report form (Apr 22, 2013) 

Saudi Arabia Ministry of Health (MOH)

MERS-CoV Page 
Infection prevention and control precautions (May 15, 2013)
Frequently asked questions
Procedures for suspected or confirmed cases 
Media Statements  

Twitter 

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers (@FluTrackers)
Jason Gale (@jwgale)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
Ian M Mackay, PhD (@MackayIM)
Maia Majumder, MPH (@maiamajumder)
NPR Global Health (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

Recent Literature

Adney DR, Bielefeldt-Ohmann H, Hartwig AE, et al. Infection, replication, and transmission of Middle East respiratory syndrome coronavirus in alpacas. Emerg Infect Dis 2016 Jun;22(6):1031-7

Al Hammadi ZM, Chu DK, Eltahir YM, et al. Asymptomatic MERS-CoV infection in humans possibly linked to infected camels imported from Oman to United Arab Emirates, May 2015. Emerg Infect Dis 2015 Dec;21(12)

Al Hosani FL, Pringle K, Al Mulla M, et al. Response to emergence of Middle East respiratory syndrome coronavirus, Abu Dhabi, United Arab

Alsahafi AJ, Cheng AC. The epidemiology of Middle East respiratory syndrome (MERS) coronavirus in the Kingdom of Saudi Arabia, 2012-2015. Int J Infect Dis 2016 (published online Feb 10)

Alshukairi AN, Khalid I, Ahmed WA, et al. Antibody response and disease severity in healthcare worker MERS survivors. Emerg Infect Dis 2016 (published online Apr 27)

Arabi Y, Hajeer AH, Luke T, et al. Feasibility of using convalescent plasma immunotherapy for MERS-CoV infection, Saudi Arabia. Emerg Infect Dis 2016 (published online Jul 20)

Arwady MA, Alraddadi B, Basler C, et al. Middle East respiratory syndrome coronavirus transmission in extended family, Saudi Arabia, 2014. Emerg Infect Dis 2016 (published online Jul 15)

Arwady MA, Alraddadi B, Basler C, et al. Middle East respiratory syndrome coronavirus transmission in extended family, Saudi Arabia, 2014. Emerg Infect Dis 2016 (published online May 18)

Assiri A, Abedi GR, Almasry M, et al. Middle East respiratory syndrome coronavirus infection during pregnancy: a report of 5 cases from Saudi Arabia. Clin Infect Dis 2016 (published online Jun 28)

Assiri A, Abedi GR, Saeed AAB, et al. Multifacility outbreak of Middle East respiratory syndrome in Taif, Saudi Arabia. Emerg Infect Dis 2015 (published online Nov 2)

Assiri AM, Midgley CM, Abedi GR, et al. Epidemiology of a novel recombinant MERS-CoV in humans in Saudi Arabia. J Infect Dis 2016 (published online Jun 14)

Atabani, SF, Wilson S, Overton-Lewis C, et al. Active screening and surveillance in the United Kingdom for Middle East respiratory syndrome coronavirus in returning travelers and pilgrims from the Middle East — a prospective descriptive study for the period 2013-2015. Int J Infect Dis 2016 (published online Apr 23)

Badawi A, Ryoo SG. Prevalence of comorbidities in the Middle East respiratory syndrome coronavirus (MERS-CoV): a systematic review and meta-analysis. Int J Infect Dis 2016 (published online Jun 21)

Balkhy HH, Alenazi TH, Alshamrani MM, et al. Nosocomial outbreak of Middle East respiratory syndrome in a large tertiary care hospital — Riyadh, Saudi Arabia, 2015. (Notes from the field) MMWR 2016 Feb 19;65(6):163-4

Butt TS, Koutlakis-Barron I, AlJumaah S, et al. Infection control and prevention practices implemented to reduce transmission risk of Middle East respiratory syndrome-coronavirus in a tertiary care institution in Saudi Arabia. Am J Infect Control 2016 (published online Feb 25)

Cauchemez S, Nouvellet P, Cori A, et al. Unraveling the drivers of MERS-CoV transmission. Proc Natl Acad Sci USA 2016 (published online Jul 25)

Cho SY, Kang JM, Ha YE, et al. MERS-CoV outbreak following a single patient exposure in an emergency room in South Korea: an epidemiological outbreak study. Lancet 2016 (published online Jul 8)

Chowell G, Abdirizak F, Lee S, et al. Transmission characteristics of MERS and SARS in the healthcare setting: a comparative study. BMC Medicine 2015 Sep 3;13:210

Chu DK, Oladipo JO, Perera RA, et al. Middle East respiratory syndrome coronavirus (MERS-COV) in dromedary camels in Nigeria, 2015. Euro Surveill 2015 Dec 10;20(49):pii=30086

Chu J, Zhou J, Wong BH, et al. Middle East respiratory syndrome coronavirus efficiently infects human primary T lymphocytes and activates the extrinsic and intrinsic apoptosis pathways. J Infect Dis 2015 (published online Jul 22)

Corman VM, Albarrak AM, Omrani AS, et al. Viral shedding and antibody response in 37 patients with MERS-coronavirus infection. Clin Infect Dis 2015 (published online Nov 12)

Corti D, Zhao J, Pedotti M, et al. Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus. Proc Natl Acad Sci 2015 (published online Jul 27)

Crameri G, Durr PA, Klein R, et al. Experimental infection and response to rechallenge of alpacas with Middle East respiratory syndrome coronavirus. Emerg Infect Dis 2016 (published online Mar 3)

Deem SL, Fevre EM, Kinnaird M, et al. Serological evidence of MERS-CoV antibodies in dromedary camels (Camelus dromedaries) in Laikipia County, Kenya. PLoS One 2015 Oct 16;10(10):e0140125

Excler JL, Delvecchio CJ, Wiley RE, et al. Toward developing a preventive MERS-CoV vaccine — report from a workshop organized by the Saudi Arabia Ministry of Health and the International Vaccine Institute, Riyadh, Saudi Arabia, November 14-15, 2015. Emerg Infect Dis 2016 (published online Jun 24)

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