MERS-CoV

Middle East respiratory syndrome coronavirus

Recent News

Sep 22, 2017

News Scan for Sep 22, 2017

MERS in UAE
Vaccine-related polio
More chikungunya in France, Italy
Waning flu vaccine protection
H5N8 in South Africa
Sep 19, 2017

News Scan for Sep 19, 2017

H7N9 vaccine development
Cyclospora cases rise
MERS vaccine trial
Zika transmission prediction
Nigerian cholera vaccination
Sep 12, 2017
ICU patient

MERS mortality linked to age, illness severity, hospital infection

In addition, Oman reports its first MERS case of the year, in a middle-aged man.

Sep 11, 2017

News Scan for Sep 11, 2017

Campylobacter and puppies
Salmonella in papayas
Saudi MERS case
H5N6 reassortants
Sep 07, 2017

News Scan for Sep 07, 2017

Saudi MERS case
Zika retina damage
VHF PPE profile
Yellow fever in Brazil
Pakistani polio case
Sep 06, 2017

News Scan for Sep 06, 2017

Two MERS cases
Newer rapid flu tests
Zika-GBS link
More Cyclospora
Sep 05, 2017

News Scan for Sep 05, 2017

Saudi MERS case
CRE treatment
Cholera in Yemen
Chikungunya drop
Sep 01, 2017

News Scan for Sep 01, 2017

Saudi MERS infection
New polio cases
ESBL E coli in Germany
Aug 30, 2017

News Scan for Aug 30, 2017

Saudi MERS cases
New Chagas drug
Avian flu outbreaks
Ebola progression
Cholera in Yemen
High C diff rates
Aug 28, 2017

Saudi Arabia, UAE report MERS cases days before hajj

The annual Muslim pilgrimage to Mecca begins on Wednesday.

Resources & Literature

Resources

 

Jump to Recent Literature

 

Last updated Oct 8, 2014

Latest Cases & General Information

Frequently updated case list from FluTrackersTransmission electron micrograph of Middle East Respiratory Syndrome Coronavirus
Disease outbreak news from WHO
Maia Majumder, MPH, MERS resources on Tumblr
Virology Down Under MERS-CoV page
Naming of MERS-CoV from Science (May 6, 2013)
Genetic sequence of MERS-CoV from PHE

Health Agency Documents

World Health Organization (WHO)

MERS-CoV page 
List of latest case updates
Summary updates landing page
Latest risk assessment (Apr 24, 2014)
Frequently asked questions (May 9, 2014)
Interim Case Definitions (Jul 14, 2014)
Guidance on conducting case-control studies (Jul 15, 2014)
Interim surveillance recommendations (Jun 27, 2013)
Interim recommendations for laboratory testing (Sep 16, 2o13)
Seroepidemiological investigation of contacts (Nov 19, 2013)                                                                     Risk factors of infection among health care personnel (Jan 27, 2014)
Guidance for health care professionals (May 6, 2013)
Clinical management (Feb 11, 2013)
Home care for patients with MERS-CoV infection (Aug 8, 2013)
Travel recommendations (Jun 5, 2013)
Travel advice for pilgrims (Jun 3, 2014)
Naming of the novel coronavirus (May 28, 2013)

US Centers for Disease Control and Prevention (CDC)

MERS-CoV page
Press release on first US case
(May 2, 2014)
Press release on clearing of contacts of first 2 US cases (Jun 17, 2014)
Health Alert Network advisory (May 3, 2014)
Frequently asked questions
(Aug 4, 2014)
Case definitions (Jun 25, 2014)
Interim guidance for healthcare professionals (Jul 29, 2014)
Guidance for travelers (May 21, 2014)
Infection prevention and control guidelines (Jul 11, 2014)
Information and guidance for clinicians (Jun 18, 2013)
Guidance on air medical transport for MERS patients (Jul 3, 2014)

Interim guidance for airline crew
(Mar 10, 2014)
Guidelines for evaluation of MERS-CoV (Jun 7, 2013)                                                                                   Interim guidelines for collection, processing and transport of clinical specimens (Jun 7, 2013)          Interim guidance for preventing MERS-CoV from spreading in homes and communities (Jul 11, 2014)
Interim home care and isolation guidance for MERS-CoV (Jul 11, 2014)
Advanced molecular detection (Aug 25, 2014)
MERS-CoV Images                                                   

European Centre for Disease Prevention and Control (ECDC)

MERS-CoV page
Updated rapid risk assessment (Apr 25, 2014) 
Epidemiologic update
(May 16, 2014)

Public Health England (PHE)

MERS-CoV page
Key facts  (Oct 4, 2013)
Risk assessment (May 2, 2014)
Treatment of MERS-CoV: Decision support tool (Jul 14, 2014)
Infection control advice (Jun 28, 2013)
Primary care algorithm for MERS & avian flu (May 28, 2014)
Algorithm for management of possible cases (Jul 14, 2014)
Algorithm for management of close contacts (May 16, 2014)
Epidemiologic protocols (Nov 11, 2013)

Food and Drug Administration (FDA)

RT-PCR Assay fact sheet for health care professionals (Jun 12, 2014)
RT-PCR assay fact sheet for patients (Jun 12, 2014) 
Emergency use authorization (Jun 10, 2014)

World Organization for Animal Health (OIE)

Questions and answers  (Aug 2014)

Public Health Agency of Canada (PHAC)

Risk assessment (Oct 8, 2014)
Public health notice (Oct 1, 2014)
Travel health notice (Jul 24, 2014)
Infection prevention and control guidance (Oct 4, 2013)
Interim case definition (Sep 23, 2013)
Coronavirus in animals (May 28, 2013)
Case report form (Apr 22, 2013) 

Saudi Arabia Ministry of Health (MOH)

MERS-CoV Page 
Infection prevention and control precautions (May 15, 2013)
Frequently asked questions
Procedures for suspected or confirmed cases 
Media Statements  

Twitter 

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers (@FluTrackers)
Jason Gale (@jwgale)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
Ian M Mackay, PhD (@MackayIM)
Maia Majumder, MPH (@maiamajumder)
NPR Global Health (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

Recent Literature

Abolfotouh MA, AlQarni AA, Al-Ghamdi SM, et al. An assessment of the level of concern among hospital-based health-care workers regarding MERS outbreaks in Saudi Arabia. BMC Infect Dis 2017 Jan 3;17:4

Adegboye OA, Gayawan E, Hanna F. Spatial modelling of contribution of individual level risk factors for mortality from Middle East respiratory syndrome coronavirus in the Arabian Peninsula. PLoS One 2017 Jul 31;12(7):e0181215

Ahmed AE. Diagnostic delays in 537 symptomatic cases of MERS-CoV infection in Saudi Arabia. Int J Infect Dis 2017 (published online Jul 17)

Ahmed AE. The predictors of 3- and 30-day mortality in 660 MERS-CoV patients. BMC Infect Dis 2017 Sep 11;17:615

Alenazi TH, Al Arbash H, El-Saed A, et al. Identified transmission dynamics of Middle East respiratory syndrome coronavirus infection during an outbreak: implications of an overcrowded emergency department. Clin Infect Dis 2017 (published online May 31)

Ali M, El-Shesheny R, Kandeil A, et al. Cross-sectional surveillance of Middle East respiratory syndrome coronavirus (MERS-COV) in dromedary camels and other mammals in Egypt, August 2015 to January 2016. Euro Surveill 2017 Mar 16;22(11):pii=30487

Alraddadi BM, Al-Salmi HS, Jacobs-Slifka K, et al. Risk factors for Middle East respiratory syndrome coronavirus infection among healthcare personnel. Emerg Infect Dis 2016 (published online Oct 11)

Anthony SJ, Gilardi K, Menachery VD, et al. Further evidence for bats as the evolutionary source of Middle East respiratory syndrome coronavirus. mBio 2017 Apr 4;8(2):e00373-17

Arabi YM, Balkhy HH, Hayden FG, et al. Middle East respiratory syndrome. N Engl J Med 2017 Feb 9;376(6):584-94

Aung KT, Hsu LY, Koh TH, et al. Prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in retail food in Singapore. Antimicrob Resist Infect Control 2017 Sep 4;6:94

Chen Z, Bao L, Chen C, et al. Human neutralizing monoclonal antibody efficiently inhibits MERS-CoV replication in common marmoset. J Infect Dis 2017 (published online May 2)

Choe PG, Perera RAPM, Park WB, et al. MERS-CoV antibody responses 1 year after symptom onset, South Korea, 2015. Emerg Infect Dis 2017 (published online May 8)

de Wit E, Feldmann F, Horne E, et al. Domestic pig unlikely reservoir for MERS-CoV. Emerg Infect Dis 2017 (published online Mar 17)

El Bushra HE, Al Arbash HA, Mohammed M, et al. Outcome of strict implementation of infection prevention control measures during an outbreak of Middle East respiratory syndrome. Am J Infect Control 2017 (published online Feb 8)

Foote MMK, Styles TS, Quinn CL. Assessment of hospital emergency department response to potentially infectious diseases using unannounced mystery patient drills — New York City, 2016. MMWR 2017 Sep 15;66(36):945-9

Hemida MG, Alnaeem A, Chu DKW, et al. Longitudinal study of Middle East Respiratory Syndrome coronavirus infection in dromedary camel herds in Saudi Arabia, 2014-2015. Emerg Microbes Infect 2017 (published online Jun 21)

Kim SW, Park JW, Jung HD, et al. Risk factors for transmission of Middle East respiratory syndrome coronavirus infection during the 2015 outbreak in South Korea. Clin Infect Dis 2016 (published online Dec 10)

Lee JY, Kim YJ, Chung EH, et al. The clinical and virological features of the first imported case causing MERS-CoV outbreak in South Korea, 2014. BMC Infect Dis 2017 Jul 14;17:498

Lin SC, Ho CT, Chuo WH, et al. Effective inhibition of MERS-CoV infection by resveratrol. BMC Infect Dis 2017 Feb 13;17:144

Lippold SA, Objio T, Vonnahme L, et al. Conveyance contact investigation for imported Middle East respiratory syndrome cases, United States, May 2014. Emerg Infect Dis 2017 (published online Aug 17)

Miguel E, Chevalier V, Ayelet G, et al. Risk factors for MERS coronavirus infection in dromedary camels in Burkina Faso, Ethiopia, and Morocco, 2015. Euro Surveill 2017 Mar 30;22(13):pii=30498

Mohd HA, Memish ZA, Alfaraj SH, et al. Predictors of MERS-CoV infection: a large case control study of patients presenting with ILI at a MERS-CoV referral hospital in Saudi Arabia. Travel Med Infect Dis 2016 (published online Sep 24)

Moon SY, Son JS. Infectivity of an asymptomatic patient with Middle East respiratory syndrome coronavirus infection. Clin Infect Dis 2017 (published online Apr 22)

Nam HS, Park JW, Ki M, et al. High fatality rates and associated factors in two hospital outbreaks of MERS in Daejeon, the Republic of Korea. Int J Infect Dis 2017 (published online Feb 19)

Oh MD, Park WB, Choe PG, et al. Viral load kinetics of MERS coronavirus infection. (Letter) N Engl J Med 2016 Sep 29;375(13):1303-5

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