Middle East respiratory syndrome coronavirus

Recent News

Mar 18, 2019

News Scan for Mar 18, 2019

Measles spreads in NY, NJ, US
Saudi MERS cases
AAP on flu shots, vaccine exemptions
Suspected Nipah in Bangladesh
Avian flu in Nepal, Denmark
Mar 14, 2019

News Scan for Mar 14, 2019

Veterinary plague exposure
Butterball turkey recall
Saudi MERS details
Avian flu on 3 continents
Mar 13, 2019

News Scan for Mar 13, 2019

Acting FDA acting chief named
MERS-CoV in Kenyan camels
Subclinical Nipah infections
Avian flu in Iran, Vietnam
Mar 12, 2019

MERS-CoV infects 2 more in Saudi Arabia, 102 this year

Fifty-seven cases are linked to the outbreak in Wadi ad-Dawasir.

Mar 11, 2019

News Scan for Mar 11, 2019

MERS in Saudi hot spots
Zika pediatric outcomes
WHO global flu strategy
Zoonotic disease guide
Measles in Europe
Mar 08, 2019

News Scan for Mar 08, 2019

Five new Ebola cases in DRC
True cost of not vaccinating
MERS in Saudi Arabia
Pregnancy infections and autism
New polio case in Nigeria
Mar 07, 2019

News Scan for Mar 07, 2019

Saudi MERS cases
Yellow fever in South America
Absenteeism and illness
Flu vaccine and heart attack
Mar 06, 2019

News Scan for Mar 06, 2019

New Saudi MERS case
WHO organizational reform
Cost of measles in health workers
First Marburg vaccine
Bayer's indoor insecticide
Mar 05, 2019

News Scan for Mar 05, 2019

FDA chief resigns
MMR vaccine not tied to autism (again)
MERS across Saudi Arabia
Lassa fever decline in Nigeria
Global flu update
Mar 04, 2019
Oman map

Oman reports second MERS cluster, 8 new cases, 2 deaths

Also, the virus sickened four more people in Saudi Arabia over the past few days, three from Riyadh.

Resources & Literature



Jump to Recent Literature


Last updated Oct 8, 2014

Latest Cases & General Information

Frequently updated case list from FluTrackersTransmission electron micrograph of Middle East Respiratory Syndrome Coronavirus
Disease outbreak news from WHO
Maia Majumder, MPH, MERS resources on Tumblr
Virology Down Under MERS-CoV page
Naming of MERS-CoV from Science (May 6, 2013)
Genetic sequence of MERS-CoV from PHE

Health Agency Documents

World Health Organization (WHO)

MERS-CoV page 
List of latest case updates
Summary updates landing page
Latest risk assessment (Apr 24, 2014)
Frequently asked questions (May 9, 2014)
Interim Case Definitions (Jul 14, 2014)
Guidance on conducting case-control studies (Jul 15, 2014)
Interim surveillance recommendations (Jun 27, 2013)
Interim recommendations for laboratory testing (Sep 16, 2o13)
Seroepidemiological investigation of contacts (Nov 19, 2013)                                                                     Risk factors of infection among health care personnel (Jan 27, 2014)
Guidance for health care professionals (May 6, 2013)
Clinical management (Feb 11, 2013)
Home care for patients with MERS-CoV infection (Aug 8, 2013)
Travel recommendations (Jun 5, 2013)
Travel advice for pilgrims (Jun 3, 2014)
Naming of the novel coronavirus (May 28, 2013)

US Centers for Disease Control and Prevention (CDC)

MERS-CoV page
Press release on first US case
(May 2, 2014)
Press release on clearing of contacts of first 2 US cases (Jun 17, 2014)
Health Alert Network advisory (May 3, 2014)
Frequently asked questions
(Aug 4, 2014)
Case definitions (Jun 25, 2014)
Interim guidance for healthcare professionals (Jul 29, 2014)
Guidance for travelers (May 21, 2014)
Infection prevention and control guidelines (Jul 11, 2014)
Information and guidance for clinicians (Jun 18, 2013)
Guidance on air medical transport for MERS patients (Jul 3, 2014)

Interim guidance for airline crew
(Mar 10, 2014)
Guidelines for evaluation of MERS-CoV (Jun 7, 2013)                                                                                   Interim guidelines for collection, processing and transport of clinical specimens (Jun 7, 2013)          Interim guidance for preventing MERS-CoV from spreading in homes and communities (Jul 11, 2014)
Interim home care and isolation guidance for MERS-CoV (Jul 11, 2014)
Advanced molecular detection (Aug 25, 2014)
MERS-CoV Images                                                   

European Centre for Disease Prevention and Control (ECDC)

MERS-CoV page
Updated rapid risk assessment (Apr 25, 2014) 
Epidemiologic update
(May 16, 2014)

Public Health England (PHE)

MERS-CoV page
Key facts  (Oct 4, 2013)
Risk assessment (May 2, 2014)
Treatment of MERS-CoV: Decision support tool (Jul 14, 2014)
Infection control advice (Jun 28, 2013)
Primary care algorithm for MERS & avian flu (May 28, 2014)
Algorithm for management of possible cases (Jul 14, 2014)
Algorithm for management of close contacts (May 16, 2014)
Epidemiologic protocols (Nov 11, 2013)

Food and Drug Administration (FDA)

RT-PCR Assay fact sheet for health care professionals (Jun 12, 2014)
RT-PCR assay fact sheet for patients (Jun 12, 2014) 
Emergency use authorization (Jun 10, 2014)

World Organization for Animal Health (OIE)

Questions and answers  (Aug 2014)

Public Health Agency of Canada (PHAC)

Risk assessment (Oct 8, 2014)
Public health notice (Oct 1, 2014)
Travel health notice (Jul 24, 2014)
Infection prevention and control guidance (Oct 4, 2013)
Interim case definition (Sep 23, 2013)
Coronavirus in animals (May 28, 2013)
Case report form (Apr 22, 2013) 

Saudi Arabia Ministry of Health (MOH)

MERS-CoV Page 
Infection prevention and control precautions (May 15, 2013)
Frequently asked questions
Procedures for suspected or confirmed cases 
Media Statements  


Helen Branswell (@HelenBranswell)
Michael Coston (@Fla_Medic)
Martin Enserink (@martinenserink)
FluTrackers (@FluTrackers)
Jason Gale (@jwgale)
Gregory Hartl (@HaertlG) (@healthmap)
Crawford Kilian (@crof)
Ian M Mackay, PhD (@MackayIM)
Maia Majumder, MPH (@maiamajumder)
NPR Global Health (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

Recent Literature

Ahmed AE, Al-Jahdali H, Alaqeel M, et al. Factors associated with recovery delay in a sample of patients diagnosed by MERS-CoV rRT-PCR: a Saudi Arabian multicenter retrospective study. Influenza Other Respir Viruses 2018 (published online Apr 25)

Al-Abdely HM, Midgley CM, Alkhamis AM, et al. Middle East respiratory syndrome coronavirus infection dynamics and antibody responses among clinically diverse patients, Saudi Arabia. Emerg Infect Dis 2019 Apr;25(4):753-66

Al-Tawfiq JA, Abdrabalnabi R, Taher A, et al. Infection control influence of Middle East respiratory syndrome coronavirus: a hospital-based analysis. Am J Infect Control 2018 (published online Nov 27)

Al-Tawfiq JA, Gautret P. Asymptomatic Middle East respiratory syndrome coronavirus (MERS-CoV) infection: extent and implications for infection control: a systematic review. Travel Med Infect Dis 2018 (published online Dec 11)

Al-Tawfiq JA, Memish ZA. Lack of seasonal variation of Middle East respiratory syndrome coronavirus (MERS-CoV). Travel Med Infect Dis 2018 (published online Sep 12)

Alfaraj SH, Al-Tawfiq JA, Altuwaijri TA, et al. Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia. Front Med 2018 (published online Apr 6)

Alfaraj SH, Al-Tawfiq JA, Assiri AY, et al. Clinical predictors of mortality of Middle East respiratory syndrome (MERS) infection: a cohort study. Travel Med Infect Dis 2019 (published online Mar 11)

Alfaraj SH, Al-Tawfiq JA, Memish ZA. Middle East respiratory syndrome coronavirus intermittent positive cases: implications for infection control. Am J Infect Control 2018 (published online Oct 20)

Alqahtani FY, Aleanizy FS, Ali El Hadi Mohamed R, et al. Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus: a retrospective study. Epidemiol Infect 2018 (published online Nov 5)

Alraddadi BM, Qushmaq I, Al‐Hameed FM, et al. Noninvasive ventilation in critically ill patients with the Middle East respiratory syndrome. Influenza Other Respir Viruses 2019 (published online Mar 19)

Alshukairi AN, Zheng J, Zhao J, et al. High prevalence of MERS-CoV infection in camel workers in Saudi Arabia. mBio 2018 (published online Oct 30)

Aman S, Aljaber MI, Alwehaibi AI, et al. Awareness of MERS-CoV among staff members of Prince Sultan Military Medical City in Riyadh, Saudi Arabia. bioRxiv 2018 Nov 19

Amer H, Alqahtani AS, Alaklobi F, et al. Healthcare workers exposure to Middle East respiratory syndrome corona virus (MERS-CoV): revision of screening strategies urgently needed. Int J Infect Dis 2018 (published online Apr 9)

Amer H, Alqahtani AS, Alzoman H, et al. Unusual presentation of Middle East respiratory syndrome coronavirus leading to a large outbreak in Riyadh during 2017. Am J Infect Control 2018 (published online Apr 13)

Chung YS, Kim JM, Kim HM, et al. Genetic characterization of Middle East respiratory syndrome coronavirus, South Korea, 2018. Emerg Infect Dis 2019 (published online Feb 12)

David D, Rotenberg D, Khinich E, et al. Middle East respiratory syndrome coronavirus specific antibodies in naturally exposed Israeli llamas, alpacas and camels. One Health 2018 (published online May 4)

Dighe A, Jombart T, Van Kerkhove MD, et al. A systematic review of MERS-CoV (Middle East respiratory syndrome coronavirus) seroprevalence and viral RNA prevalence in dromedary camels: implications for animal vaccination. bioRxiv 2019 (published online Mar 11)

Farag EAB, Nour M, El Idrissi A, et al. Survey on implementation of One Health approach for MERS-CoV preparedness and control in Gulf Cooperation Council and Middle East countries. Emerg Infect Dis 2019 (published online Jan 31)

Kandeil A, Gomaa M, Shehata M, et al. Middle East respiratory syndrome coronavirus infection in non-camelid domestic mammals. Emerg Microbes Infect 2019 (published online Jan 16)

Park WB, Poon LLM, Choi SJ, et al. Replicative virus shedding in the respiratory tract of the patients with Middle East respiratory syndrome coronavirus infection. Int J Infect Dis 2018 (published online May 9)

Payne DC, Biggs HM, Al-Abdallat MM, et al. Multi-hospital outbreak of a Middle East respiratory syndrome coronavirus deletion variant, Jordan: a molecular, serologic, and epidemiologic investigation. Open Forum Infect Dis 2018 (published online Apr 28)

So RTY, Perera RAPM, Oladipo JO, et al. Lack of serological evidence of Middle East respiratory syndrome coronavirus infection in virus exposed camel abattoir workers in Nigeria, 2016. Euro Surveill 2018 Aug 9;23(32):pii=1800175

Te N, Vergara-Alert J, Lehmbecker A, et al. Co-localization of Middle East respiratory syndrome coronavirus (MERS-CoV) and dipeptidyl peptidase-4 in the respiratory tract and lymphoid tissues of pigs and llamas. Transbound Emerg Dis 2018 (published online Dec 6)

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