MERS-CoV

Middle East respiratory syndrome coronavirus

Recent News

Jun 18, 2018
Hospital patient

MERS in Saudi Arabia this year includes hospital, household clusters

Exposure in household settings can occur through close unprotected contact when caring for a family member infected with MERS-CoV.

Jun 11, 2018

News Scan for Jun 11, 2018

MERS household cluster
US flu deaths in kids
Polio in Venezuela
Cyclospora infections in 2 states
Measles in Brazil
H5N1, H5N8 poultry outbreaks
May 31, 2018
Stately camel

Cluster of MERS illnesses reported in Saudi family

The first patient got sick after exposure to camels and their milk, and six others contracted the virus in the household setting.

May 29, 2018

News Scan for May 29, 2018

MERS case in UAE
Southern Hemisphere flu rise
May 18, 2018

News Scan for May 18, 2018

Declining US flu markers
MERS treatment trial launch
Novel poxvirus in Texas
H5N1 in Nepalese poultry
May 16, 2018

News Scan for May 16, 2018

Pandemic exercise lessons
Saudi MERS case
New rapid rabies test
May 07, 2018
Camels in Negev Desert

Study: Israeli camels exposed to MERS, but no sign of virus circulation

There was no sign of active MERS-CoV circulation in recent years.

May 03, 2018

News Scan for May 03, 2018

Saudi MERS case
Chronic wasting and mineral licks
Salmonella in rattlesnake pills
Ebola and retinal lesions
Infection prevention guide
Apr 30, 2018

News Scan for Apr 30, 2018

Universal flu vaccine funds
Pneumococcal vaccine failure
Saudi MERS deaths
Hospital-acquired malaria
Aspergillosis burden
Apr 26, 2018

News Scan for Apr 26, 2018

Modified FMD virus
MERS in Saudi Arabia
Midwest measles
Rotavirus patterns
Listeria and soft cheese
CWD not spread to monkeys

Resources & Literature

Resources

 

Jump to Recent Literature

 

Last updated Oct 8, 2014

Latest Cases & General Information

Frequently updated case list from FluTrackersTransmission electron micrograph of Middle East Respiratory Syndrome Coronavirus
Disease outbreak news from WHO
Maia Majumder, MPH, MERS resources on Tumblr
Virology Down Under MERS-CoV page
Naming of MERS-CoV from Science (May 6, 2013)
Genetic sequence of MERS-CoV from PHE

Health Agency Documents

World Health Organization (WHO)

MERS-CoV page 
List of latest case updates
Summary updates landing page
Latest risk assessment (Apr 24, 2014)
Frequently asked questions (May 9, 2014)
Interim Case Definitions (Jul 14, 2014)
Guidance on conducting case-control studies (Jul 15, 2014)
Interim surveillance recommendations (Jun 27, 2013)
Interim recommendations for laboratory testing (Sep 16, 2o13)
Seroepidemiological investigation of contacts (Nov 19, 2013)                                                                     Risk factors of infection among health care personnel (Jan 27, 2014)
Guidance for health care professionals (May 6, 2013)
Clinical management (Feb 11, 2013)
Home care for patients with MERS-CoV infection (Aug 8, 2013)
Travel recommendations (Jun 5, 2013)
Travel advice for pilgrims (Jun 3, 2014)
Naming of the novel coronavirus (May 28, 2013)

US Centers for Disease Control and Prevention (CDC)

MERS-CoV page
Press release on first US case
(May 2, 2014)
Press release on clearing of contacts of first 2 US cases (Jun 17, 2014)
Health Alert Network advisory (May 3, 2014)
Frequently asked questions
(Aug 4, 2014)
Case definitions (Jun 25, 2014)
Interim guidance for healthcare professionals (Jul 29, 2014)
Guidance for travelers (May 21, 2014)
Infection prevention and control guidelines (Jul 11, 2014)
Information and guidance for clinicians (Jun 18, 2013)
Guidance on air medical transport for MERS patients (Jul 3, 2014)

Interim guidance for airline crew
(Mar 10, 2014)
Guidelines for evaluation of MERS-CoV (Jun 7, 2013)                                                                                   Interim guidelines for collection, processing and transport of clinical specimens (Jun 7, 2013)          Interim guidance for preventing MERS-CoV from spreading in homes and communities (Jul 11, 2014)
Interim home care and isolation guidance for MERS-CoV (Jul 11, 2014)
Advanced molecular detection (Aug 25, 2014)
MERS-CoV Images                                                   

European Centre for Disease Prevention and Control (ECDC)

MERS-CoV page
Updated rapid risk assessment (Apr 25, 2014) 
Epidemiologic update
(May 16, 2014)

Public Health England (PHE)

MERS-CoV page
Key facts  (Oct 4, 2013)
Risk assessment (May 2, 2014)
Treatment of MERS-CoV: Decision support tool (Jul 14, 2014)
Infection control advice (Jun 28, 2013)
Primary care algorithm for MERS & avian flu (May 28, 2014)
Algorithm for management of possible cases (Jul 14, 2014)
Algorithm for management of close contacts (May 16, 2014)
Epidemiologic protocols (Nov 11, 2013)

Food and Drug Administration (FDA)

RT-PCR Assay fact sheet for health care professionals (Jun 12, 2014)
RT-PCR assay fact sheet for patients (Jun 12, 2014) 
Emergency use authorization (Jun 10, 2014)

World Organization for Animal Health (OIE)

Questions and answers  (Aug 2014)

Public Health Agency of Canada (PHAC)

Risk assessment (Oct 8, 2014)
Public health notice (Oct 1, 2014)
Travel health notice (Jul 24, 2014)
Infection prevention and control guidance (Oct 4, 2013)
Interim case definition (Sep 23, 2013)
Coronavirus in animals (May 28, 2013)
Case report form (Apr 22, 2013) 

Saudi Arabia Ministry of Health (MOH)

MERS-CoV Page 
Infection prevention and control precautions (May 15, 2013)
Frequently asked questions
Procedures for suspected or confirmed cases 
Media Statements  

Twitter 

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers (@FluTrackers)
Jason Gale (@jwgale)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
Ian M Mackay, PhD (@MackayIM)
Maia Majumder, MPH (@maiamajumder)
NPR Global Health (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

Recent Literature

Adegboye OA, Gayawan E, Hanna F. Spatial modelling of contribution of individual level risk factors for mortality from Middle East respiratory syndrome coronavirus in the Arabian Peninsula. PLoS One 2017 Jul 31;12(7):e0181215

Ahmed AE, Al-Jahdali H, Alaqeel M, et al. Factors associated with recovery delay in a sample of patients diagnosed by MERS-CoV rRT-PCR: a Saudi Arabian multicenter retrospective study. Influenza Other Respir Viruses 2018 (published online Apr 25)

Ahmed AE, Al-Jahdali H, Alshukairi AN, et al. Early identification of pneumonia patients at increased risk of MERS-CoV infection in Saudi Arabia. Int J Infect Dis 2018 (published online Mar 14)

Ahmed AE. Diagnostic delays in 537 symptomatic cases of MERS-CoV infection in Saudi Arabia. Int J Infect Dis 2017 (published online Jul 17)

Ahmed AE. The predictors of 3- and 30-day mortality in 660 MERS-CoV patients. BMC Infect Dis 2017 Sep 11;17:615

Alfaraj SH, Al-Tawfiq JA, Altuwaijri TA, et al. Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia. Front Med 2018 (published online Apr 6)

Alfaraj SH, Al-Tawfiq JA, Altuwaijri TA, et al. Middle East respiratory syndrome coronavirus transmission among health care workers: implication for infection control. Am J Infect Control 2017 (published online Sep 25)

Amer H, Alqahtani AS, Alaklobi F, et al. Healthcare workers exposure to Middle East respiratory syndrome corona virus (MERS-CoV): revision of screening strategies urgently needed. Int J Infect Dis 2018 (published online Apr 9)

Amer H, Alqahtani AS, Alzoman H, et al. Unusual presentation of Middle East respiratory syndrome coronavirus leading to a large outbreak in Riyadh during 2017. Am J Infect Control 2018 (published online Apr 13)

Aung KT, Hsu LY, Koh TH, et al. Prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in retail food in Singapore. Antimicrob Resist Infect Control 2017 Sep 4;6:94

Beigel JH, Voell J, Kumar P, et al. Safety and tolerability of a novel, polyclonal human anti-MERS coronavirus antibody produced from transchromosomic cattle: a phase 1 randomised, double-blind, single-dose-escalation study. Lancet Infect Dis 2018 (published online Jan 9)

Chen L, Zhang J, Wang J, et al. Newly identified colistin resistance genes, mcr-4 and mcr-5, from upper and lower alimentary tract of pigs and poultry in China. PLoS One 2018 Mar 14;13(3):e0193957

David D, Rotenberg D, Khinich E, et al. Middle East respiratory syndrome coronavirus specific antibodies in naturally exposed Israeli llamas, alpacas and camels. One Health 2018 (published online May 4)

Dudas G, Carvalho LM, Rambaut A, et al. MERS-CoV spillover at the camel-human interface. eLife 2018 Jan 16;7:e31257

Foote MMK, Styles TS, Quinn CL. Assessment of hospital emergency department response to potentially infectious diseases using unannounced mystery patient drills — New York City, 2016. MMWR 2017 Sep 15;66(36):945-9

Hemida MG, Alnaeem A, Chu DKW, et al. Longitudinal study of Middle East Respiratory Syndrome coronavirus infection in dromedary camel herds in Saudi Arabia, 2014-2015. Emerg Microbes Infect 2017 (published online Jun 21)

Islam A, Epstein JH, Rostal MK, et al. Middle East respiratory syndrome coronavirus antibodies in dromedary camels. Bangladesh, 2015. (Letter) Emerg Infect Dis 2018 (published online Mar 22)

Kang JH, Kim EJ, Choi JH, et al. Difficulties in using personal protective equipment: training experiences with the 2015 outbreak of Middle East respiratory syndrome in Korea. Am J Infect Control 2017 (published online Oct 16)

Kieffer N, Aires-de-Sousa M, Nordmann P, et al. High rate of MCR-1-producing Escherichia coli and Klebsiella pneumoniae among pigs, Portugal. Emerg Infect Dis 2017 (published online Oct 31)

Kim Y. Nurses' experiences of care for patients with Middle East respiratory syndrome-coronavirus in South Korea. Am J Infect Control 2018 (published online Mar 1)

Lee JY, Kim G, Lim DG, et al. A Middle East respiratory syndrome screening clinic for health care personnel during the 2015 Middle East respiratory syndrome outbreak in South Korea: a single-center experience. Am J Infect Control 2017 (published online Nov 16)

Lee JY, Kim YJ, Chung EH, et al. The clinical and virological features of the first imported case causing MERS-CoV outbreak in South Korea, 2014. BMC Infect Dis 2017 Jul 14;17:498

Lippold SA, Objio T, Vonnahme L, et al. Conveyance contact investigation for imported Middle East respiratory syndrome cases, United States, May 2014. Emerg Infect Dis 2017 (published online Aug 17)

Ma X, Liu F, Liu L, et al. No MERS-CoV but positive influenza viruses in returning Hajj pilgrims, China, 2013-2015. BMC Infect Dis 2017 Nov 10;17:715

Moreno A, Lelli D, de Sabato L, et al. Detection and full genome characterization of two beta CoV viruses related to Middle East respiratory syndrome from bats in Italy. Virol J 2017 Dec 19;14:239

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