(CIDRAP News) – While many pathogens cause serious diarrhea in children in developing countries, four stand out as culprits in most of the infections, a finding that could drive new prevention strategies, an international research team reported today.
(CIDRAP News) – Norovirus has eclipsed rotavirus as the leading cause of gastroenteritis in US children and carries substantial infection and treatment costs, according to a new study led by a research team at the Centers for Disease Control and Prevention (CDC).
(CIDRAP News) – Immunization systems in Africa still have supply, financing, and sustainability issues and need urgent attention from country leaders to reach the region's health goals, African experts said yesterday.
Armah GE, Kapikian AZ, Vesikari T, et al. Efficacy, immunogenicity, and safety of two doses of a tetravalent rotavirus vaccine RRV-TV in Ghana with the first dose administered during the neonatal period. J Infect Dis 2013 Aug 1;208(3):423-31
Cardellino A, Khawaja S, Cruz ES, et al. Effectiveness of vaccination with the pentavalent rotavirus vaccine in Nicaragua as determined using the screening method. Hum Vacc Immunother 2013 Jul;9(7):1449-53
Gastanaduy PA, Curns AT, Parashar UD, et al. Gastroenteritis hospitalizations in older children and adults in the United States before and after implementation of infant rotavirus vaccination. JAMA 2013 Aug 28;310(8):851-3
Hsieh YC, TzyWu F, Hsiung CA, et al. Comparison of virus shedding after live attenuated and pentavalent reassortment rotavirus vaccine. Vaccine 2013 (published online Sep 24)
Matthijnssens J, Makagomi O, Kirkwood CD, et al. Group A rotavirus universal mass vaccination: how and to what extent will selective pressure influence prevalence of rotavirus genotypes? Expert Rev Vaccines 2012 Nov 1;11(11):1347-54
Moon S, Wang Y, Edens C, et al. Dose sparing and enhanced immunogenicity of inactivated rotavirus vaccine administered by skin vaccination using a microneedle patch. Vaccine 2013 Jul 25;31(34):3396-402
Stumpf KA, Thompson T, Sanchez PJ. Rotavirus vaccination of very low birth weight infants at discharge from the NICU. Pediatrics 2013 (published online Aug 12)
Tate JE, Mijatovic-Rustempasic S, Tam KI, et al. Comparison of 2 assays for diagnosing rotavirus and evaluating vaccine effectiveness in children with gastroenteritis. Emerg Infect Dis 2013 Aug;19(8):1245-52
Wikswo ME, Desai R, Edwards KM, et al. Clinical profile of children with norovirus disease in rotavirus vaccine era. (Letter) Emerg Infect Dis 2013 (published online Aug 27)