Recent News

Oct 18, 2017
Pulmonary tuberculosis

Studies show rise in drug-resistant TB in India, China

Almost a third of TB cases in India are multidrug-resistant, and rates are climbing in Chinese kids.

Sep 14, 2017
DNA amplification test

New rapid molecular test for MDR-TB shows promise

The fast, automated assay performs well against gold standard TB tests.

Sep 13, 2017

News Scan for Sep 13, 2017

Malaria drug show promise
Global Fund and lives saved
Aug 16, 2017

Stewardship / Resistance Scan for Aug 16, 2017

MDR- and XDR-TB in China
Patient empowerment tool for hand hygiene
Aug 04, 2017
Sample of DNA

CDC to invest millions in enhanced antibiotic resistance testing

Funds will help combat resistance, launch a TB surveillance center.

Aug 04, 2017

News Scan for Aug 04, 2017

Saudi MERS case, death
Molecular diagnostics for TB
Australian drug stewardship report
Aug 01, 2017
Tuberculosis chest x-ray

New treatments for MDR-, XDR-TB show promise in small studies

The drugs studied are bedaquiline and delamanid, both drugs of last resort.

Jul 31, 2017

Stewardship / Resistance Scan for Jul 31, 2017

Stewardship in US hospitals
Resistant E coli
Death and MDR-TB
Jul 13, 2017

Stewardship / Resistance Scan for Jul 13, 2017

MDR-TB in Georgia
Stewardship in the ED
Jun 20, 2017

Stewardship / Resistance Scan for Jun 20, 2017

New antibiotic OK'd
MDR-TB in US kids
Virus tests and stewardship
Penalties for poor Rx
US Candida auris
Resistance testing

Resources & Literature

Recent Literature

Achar J, Hewison C, Cavalheiro AP, et al. Off-label use of bedaquiline in children and adolescents with multidrug-resistant tuberculosis. Emerg Infect Dis 2017 (published online Jul 31)

Adjemian J, Frankland TB, Daida YG, et al. Epidemiology of nontuberculous mycobacterial lung disease and tuberculosis, Hawaii, USA. Emerg Infect Dis 2017 (published online Feb 3)

Aibana O, Acharya X, Huang CC, et al. Nutritional status and tuberculosis risk in adult and pediatric household contacts. PLoS One 2016 Nov 11;11(11):e0166333

Aibana O, Bachmaha M, Krasiuk V, et al. Risk factors for poor multidrug-resistant tuberculosis treatment outcomes in Kyiv Oblast, Ukraine. BMC Infect Dis 2017 Feb 7;17:129

Ansumana R, Keitell S, Roberts GMT, et al. Impact of infectious disease epidemics on tuberculosis diagnostic, management and prevention services: experiences and lessons from the 2014-2015 Ebola virus disease outbreak in West Africa. Int J Infect Dis 2016 (published online Nov 3)

Arnold A, Cooke GS, Kon OM, et al. Drug resistant TB: UK multicentre study (DRUMS): treatment, management and outcomes in London and West Midlands 2008-2014. J Infect 2016 (published online Dec 18)

Benoit SR, Gregg EW, Jonnalagadda S, et al. Association of diabetes and tuberculosis disease among US-bound adult refugees, 2009-2014. (Letter) Emerg Infect Dis 2017 (published online Jan 26)

Blanco-Guillot F, Delgado-Sanchez G, Mongua-Rodriguez N, et al. Molecular clustering of patients with diabetes and pulmonary tuberculosis: a systematic review and meta-analysis. PLoS One 2017 Sep 13;12(9):e0184675

Boeree MJ, Heinrich N, Aarnoutse R, et al. High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial. Lancet Infect Dis 2016 (published online Oct 26)

Bonnett LJ, Ken-Dror G, Koh G, et al. Comparing the efficacy of drug regimens for pulmonary tuberculosis: meta-analysis of endpoints in early phase clinical trials. Clin Infect Dis 2017 (published online Apr 10)

Bourdillon PM, Goncalves CCM, Pelissari DM, et al. Increase in tuberculosis cases among prisoners, Brazil, 2009-2014. Emerg Infect Dis 2017 (published online Jan 26)

Bozorgmehr K, Razum O, Saure D, et al. Yield of active screening for tuberculosis among asylum seekers in Germany: a systematic review and meta-analysis. Euro Surveill 2017 Mar 23;22(12):pii=30491

Calligaro GL, Zikenah LS, Peter JG, et al. Effect of new tuberculosis diagnostic technologies on community-based intensified case finding: a multicenter randomized controlled trial. Lancet Infect Dis 2017 (published online Jan 4)

Cathey EF, Matthias J, Beedie KA, et al. Large tuberculosis contact investigation involving two hospitals — Okaloosa County, Florida, 2014. (Notes from the field) MMWR 2016 Dec 2;65(47):1349-50

Chen MY, Lo YC, Chen WC, et al. Recurrence after successful treatment of multidrug-resistant tuberculosis in Taiwan. PLoS One 2017 Jan 26;12(1):e0170980

Cheng MP, Chakra CNA, Yansouni CP, et al. Risk of active tuberculosis in patients with cancer: a systematic review and meta-analysis. Clin Infect Dis 2016 (published online Dec 16)

Dale KD, Tay EL, Trauer JM, et al. Comparing tuberculosis management under public and private healthcare providers: Victoria, Australia, 2002-2015. BMC Infect Dis 2017 May 3;17:324

de Vries G, Tsolova S, Anderson LF, et al. Health system factors influencing management of multidrug-resistant tuberculosis in four European Union countries — learning from country experiences. BMC Public Health 2017 Apr 19;17:334

de Vries SG, Cremers AL, Heuvelings CC, et al. Barriers and facilitators to the uptake of tuberculosis diagnostic and treatment services by hard-to-reach populations in countries of low and medium tuberculosis incidence: a systematic review of qualitative literature. Lancet Infect Dis 2017 (published online Mar 10)

Dheda K, Gumbo T, Maartens G, et al. The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis. Lancet Respir Med 2017 (published online Mar 23)

Dobler CC, Farah WH, Alsawas M, et al. Tuberculin skin test conversions and occupational exposure risk in US healthcare workers. Clin Infect Dis 2017 (published online Oct 4)

Eshetie S, Bizachew M, Dagnew M, et al. Multidrug resistant tuberculosis in Ethiopian settings and its association with previous history of anti-tuberculosis treatment: a systematic review and meta-analysis. BMC Infect Dis 2017 Mar 20;17:219

Folkvardsen DB, Norman A, Andersen AB, et al. Genomic epidemiology of a major Mycobacterium tuberculosis outbreak: retrospective cohort study in a low incidence setting using sparse time-series sampling. J Infect Dis 2017 (published online Jun28)

Gegla M, Winters N, Benedetti A, et al. Treatment of isoniazid-resistant tuberculosis with first-line drugs: a systematic review and meta-analysis. Lancet Infect Dis 2016 (published online November 16)

Gehre F, Otu J, Kendall L, et al. The emerging threat of pre-extensively drug-resistant tuberculosis in West Africa: preparing for large-scale tuberculosis research and drug resistance surveillance. BMC Med 2016 Nov 3;14:160

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