Recent News

Jan 09, 2019
Doctor prescribing using electronic tablet

Study sheds more light on delamanid role in treating MDR-TB

Safety profile was good, and sensitivity analysis favored delamanid as part of MDR-TB treatment.

Dec 03, 2018

News Scan for Dec 03, 2018

Severe Zika thrombocytopenia
Polio outbreak over in Syria
UK vaccine center, more CEPI funds
TB funding climbs
Nov 02, 2018

News Scan for Nov 02, 2018

Polio in 4 countries
Avian flu in Minnesota, Vietnam
Testing for very resistant TB
New CWD type in moose?
Oct 19, 2018

Stewardship / Resistance Scan for Oct 19, 2018

Undetected MDR-TB in South Africa
Carbapenem prescribing algorithm
Sep 27, 2018
DNA test genetic sequencing

Study heralds genetic era of TB drug susceptibility testing

Whole-genome sequencing could lead to faster, more accurate resistance testing.

Sep 26, 2018

News Scan for Sep 26, 2018

Expanded retail info in food recalls
Flu transmission and humidity
Novel pertussis vaccine
Global TB commitment
Sep 25, 2018

News Scan for Sep 25, 2018

Adjuvanted TB vaccine
Congenital syphilis surge
Undiagnosed Disease Network grows
H5N6 in Vietnamese poultry
Sep 18, 2018
Mycobacterium tuberculosis bacteria

WHO report warns efforts to end TB are falling short

TB remains high in many low- and middle-income nations, and about 558,000 people in 2017 developed rifampicin-resistant TB.

Sep 12, 2018

News Scan for Sep 12, 2018

Nigeria assist for UK monkeypox
Measles and public health cuts
Global Fund disease progress
Seqirus cell-based flu vaccine
Sep 07, 2018
Capsules and syringe

Study provides data behind new MDR-TB guidance

Newer and repurposed drugs produced better results and fewer deaths than older treatments did.

Resources & Literature

Recent Literature

Abubakar I, Drobnieswki F, Southern J, et al. Prognostic value of interferon-gamma release assays and tuberculin skin test in predicting the development of active tuberculosis (UK PREDICT TB): a prospective cohort study. Lancet Infect Dis 2018 (published online Aug 30)

Ahmad N, Ahuja SD, Akkerman OW, et al. Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis. Lancet 2018 Sep 8;392(10150):821-34

Anaraki S, Bell AJ, Perkins S, et al. Expected background rates of latent TB infection in London inner city schools: lessons from a TB contact investigation exercise in a secondary school. Epidemiol Infect 2018 (published online Aug 23)

Bei C, Fu M, Zhang Y, et al. Mortality and associated factors of patients with extensive drug-resistant tuberculosis: an emerging public health crisis in China. BMC Infect Dis 2018 Jun 7;18:261

Brent AJ, Nyundo C, Langat J, et al. Prospective observational study of incidence and preventable burden of childhood tuberculosis, Kenya. Emerg Infect Dis 2018 (published online Jan 29)

Brynildsrud OB, Pepperell CS, Suffys P, et al. Global expansion of Mycobacteium tuberculosis lineage 4 shaped by colonial migration and local adaptation. Sci Adv 2018 Oct 17;4(10):eaat5869

Chaisson LH, Duong D, Cattamanchi A, et al. Association of rapid molecular testing with duration of respiratory isolation for patients with possible tuberculosis in a US hospital. JAMA Intern Med 2018 Oct;178(10):1380-8

Chernyaeva E, Rotkevich M, Krasheninnikova K, et al. Whole-genome analysis of Mycobacterium tuberculosis from patients with tuberculous spondylitis, Russia. Emerg Infect Dis 2018 (published online Jan 29)

Chung CL, Chen YF, Lin YT, et al. Outcome of untreated lung nodules with histological but no microbiological evidence of tuberculosis. BMC Infect Dis 2018 Oct 23;18:530

Conlangeli R, Jedrey H, Kim S, et al. Bacterial factors that predict relapse after tuberculosis therapy. N Engl J Med 2018 Aug 30;379(9):823-33

Cormier M, Schwartzman K, N'Diaye DS, et al. Proximate determinants of tuberculosis in indigenous peoples worldwide: a systematic review. Lancet Glob Health 2019

Cruz AT, Starke JR. Completion rate and safety of tuberculosis infection treatment with shorter regimens. Pediatrics 2018 (published online Jan 23)

Davidson JA, Thomas HL, Maguire H, et al. Understanding TB transmission in the UK: findings from six years of MIRU-VNTR strain typing, 2010 to 2015. Am J Epidemiol 2018 (published online Jun 7)

Deshpande D, Pasipanodya JG, Srivastava S, et al. Minocycline immunomodulates via sonic hedgehog signaling and apoptosis and has direct potency against drug-resistant tuberculosis. J Infect Dis 2018 (published online Dec 28)

Desissa F, Workineh T, Beyene T. Risk factors for the occurrence of multidrug-resistant tuberculosis among patients undergoing multidrug-resistant tuberculosis treatment in East Shoa, Ethiopia. BMC Public Health 2018 Apr 2;18:422

Diallo T, Adjobimey M, Ruslami R, et al. Safety and side effects of rifampin versus isoniazid in children. N Engl J Med 2018 Aug 2;379(5):454-63

Dorjee K, Topgyal S, Dorjee C, et al. High prevalence of active and latent tuberculosis in children and adolescents in Tibetan schools in India: the Zero TB Kids initiative in Tibetan refugee children. Clin Infect Dis 2018 (published online Nov 20)

Dousa KM, Hamad A, Albirair M, et al. Impact of diabetes mellitus on the presentation and response to treatment of adults with pulmonary tuberculosis in Qatar. Open Forum Infect Dis 2018 (published online Dec 19)

Duque-Silva A, Hampole V, Cheng YN, et al. Outcomes of pediatric central nervous system tuberculosis in California, 1993-2011. J Pediatr Infect Dis Soc 2018 (published online Sep 4)

Eshetie S, Alebel A, Wagnew F, et al. Current treatment of multidrug resistant tuberculosis in Ethiopia: an aggregated and individual patients’ data analysis for outcome and effectiveness of the current regimens. BMC Infect Dis 2018 Sep 27;18:486

Faust L, McCarthy A, Schreiber Y. Recommendations for the screening of paediatric latent tuberculosis infection in indigenous communities: a systematic review of screening strategies among high-risk groups in low-incidence countries. BMC Public Health 2018 Aug 6;18:979

Ferlazzo G, Mohr E, Laxmeshwar C, et al. Early safety and efficacy of the combination of bedaquiline and delamanid for the treatment of patients with drug-resistant tuberculosis in Armenia, India, and South Africa: a retrospective cohort study. Lancet Infect Dis 2018 (published online Feb 13)

Fox GJ, Nguyen VN, Dinh NS, et al. Post-treatment mortality among patients with tuberculosis: a prospective cohort study of 10,964 patients in Vietnam. Clin Infect Dis 2018 (published online Sep 7)

Gafar F, Arifin H, Jurnalis YD, et al. Antituberculosis drug-induced liver injury in children. Pediatr Infect Dis J 2019 Jan;38(a):50-3

Garfein RS, Liu L, Cuevas-Mota J, et al. Tuberculosis treatment monitoring by video directly observed therapy in 5 health districts, California, USA. Emerg Infect Dis 2018 (published online Aug 30)

Newsletter Sign-up

Get CIDRAP news and other free newsletters.

Sign up now»


Unrestricted financial support provided by

Bentson Foundation 3MAccelerate DiagnosticsGilead Become an underwriter»