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It's too soon to know if the study applies to people, but West Nile caused fetal brain damage and death in mice.
The patients, hospitalized at a speciality center, had a variety of complications and some unusual features.
Researchers call cardinals West Nile virus "supersupressors," because their lower viral blood levels are less likely to transmit the disease back to mosquitoes.
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Giordano BV, Kaur S, Hunter FF. West Nile virus in Ontario, Canada: a twelve-year analysis of human case prevalence, mosquito surveillance, and climate data. PLoS One 2017 Aug 22;12(8):e0183568
Lopez-Ruiz N, Montano-Remacha MDC, Duran-Pla E, et al. West Nile virus outbreak in humans and epidemiological surveillance, west Andalusia, Spain, 2016. Euro Surveill 2018 Apr 5;23(14):pii=17-00261
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Platt DJ, Smith AM, Arora N, et al. Zika virus-related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice. Sci Transl Med 2018 Jan 31;10(426):eaao7090
Popescu CP, Florescu SA, Cotar AI, et al. Re-emergence of severe West Nile virus neuroinvasive disease in humans in Romania, 2012 to 2017 — implications for travel medicine. Travel Med Infect Dis 2018 (published online Mar 12)
Venter M, Pretorius M, Fuller JA, et al. West Nile virus lineage 2 in horses and other animals with neurologic disease, South Africa, 2008-2015. Emerg Infect Dis 2017 (published online Oct 30)
Worwa G, Hutton AA, Frey M, et al. Increases in the competitive fitness of West Nile virus isolates after introduction into California. Virology 2017 (published online Nov 28)
Yeung MW, Shing E, Nelder M, et al. Epidemiologic and clinical parameters of West Nile virus infections in humans: a scoping review. BMC Infect Dis 2017 Sep 6;17:609
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