Zika

Recent News

Dec 08, 2017

News Scan for Dec 08, 2017

Texas Zika cases
H7N9 survivor study
Avian flu in Europe, South Africa
Marburg outbreak over
Malaria in Mekong
Dec 06, 2017

News Scan for Dec 06, 2017

Boston BSL-4 lab OK'd
Zika infection patterns
Refugee diphtheria outbreak
Dec 05, 2017
Vaccinating teen girl

Phase 1 trials promising for 2 Zika vaccines, including shelved one

Trials of both an inactivated and a DNA vaccine showed good safety and immune response data.

Dec 05, 2017

News Scan for Dec 05, 2017

MERS infection
Dengue vaccine review
Madagascar plague
Microcephaly in Angola
Dec 04, 2017

Vector-borne Disease Scan for Dec 04, 2017

Chikungunya cases
Zika screening
Nov 28, 2017
Aedes mosquito

Takeda launches Zika vaccine trial; Chembio lands contract for rapid test

Japan-based Takeda announces the launch of a phase 1 trial of its Zika vaccine.

Nov 21, 2017

News Scan for Nov 21, 2017

Zika spread, complications
Monkeypox in Nigeria
Nov 20, 2017

News Scan for Nov 20, 2017

Saudi MERS case
Zika in Miami-Dade
Plague in Madagascar
Nov 14, 2017
Drawing blood

Brazilian study indicates Zika may have hit poor hardest

The study of people in Salvador, Brazil, shows infection rates exceeding 60% in many populations.

Nov 08, 2017
Dengue infection

Dengue study adds to evidence for antibody enhancement

The study highlights ADE, when previous virus exposure enhances disease response.

Resources & Literature

Resources

Jump to Selected Reading

 

Last updated Nov 27, 2017

Most Recently Added

aedes aegypti mosquito

News/Commentary

Drones distribute swarms of sterile mosquitoes to stop Zika and other diseases (IEEE Spectrum, Nov 20)
Assessing Zika risk in international travelers (Allison Walker, PhD, MPH, commentary on Medscape, Nov 20)
Drug used to treat malaria could help fight Zika’s damaging effects (CBS Miami, Nov 20)
Florida confirms second local Zika virus infection for 2017 (AP, Nov 17)
A plan to develop a Zika vaccine runs into controversy, as questions swirl about price and conflicts of interest (Stat, Nov 17)
Evolution of neurovirulent Zika virus (Commentary in Science, Nov 17)
Birth rate in Brazil falls to 26-year low after Zika crisis (Medical Xpress, Nov 14)
To find an effective Zika vaccine, we must include pregnant women in the trials (Commentary in The Hill, Nov 12)
Some good news, as a Zika-exposed baby turns one (WAMU, Nov 9)
US government approves 'killer' mosquitoes to fight disease (Nature News, Nov 6)
Although the number of Zika cases has fallen, the virus is unlikely to vanish (Washington Post, Nov 4)
Sexually transmitted case of Zika confirmed in Miami-Dade (Miami Herald, Nov 3)
The forgotten mothers and babies of Zika (CNN, Nov 2)
Zika virus has always been neurotropic (Virology blog, Nov 2)

CDC

Zika and animals (Jun 29, 2017)

Selected Reading

Bierle CJ, Fernandez-Alarcon C, Hernandez-Alvarado N, et al. Assessing Zika virus replication and the development of Zika-specific antibodies after a mid-gestation viral challenge in guinea pigs. PLoS One 2017 Nov 3;12(11):e0187720
Brault AC, Domi A, McDonald EM, et al. A Zika vaccine targeting NS1 protein protects immunocompetent adult mice in a lethal challenge model. Sci Rep 2017 (published online Nov 7)
Carlson CJ, Dougherty E, Boots M, et al. Consensus and conflict among ecological forecasts of Zika virus outbreaks in the United States. bioRxiv 2017 Nov 14
Coimbra BM, Coelho FC, Armstrong M, et al. Zika: an ongoing threat to women and infants. bioRxiv 2017 Nov 16
Colon-Gonzalez FJ, Peres CA, Bernardo CSS, et al. After the epidemic: Zika virus projections for Latin America and the Caribbean. PLoS Negl Trop Dis 2017 Nov 1;11(11):e0006007
Deng YQ, Zhang NN, Li XF, et al. Intranasal infection and contact transmission of Zika virus in guinea pigs. Nat Commun 2017 (Nov 21)
DeSilva M, Munoz FM, Sell E, et al. Congenital microcephaly: case definition & guidelines for data collection, analysis, and presentation of safety data after maternal immunisation. (Commentary) Vaccine 2017 (published online Nov 14)
Flamand C, Fritzell C, Matheus S, et al. The proportion of asymptomatic infections and spectrum of disease among pregnant women infected by Zika virus: systematic monitoring in French Guiana, 2016. Euro Surveill 2017 Nov 2;22(44):pii=17-00102
Fontes-Garfias CR, Shan C, Luo H, et al. Functional analysis of glycosylation of Zika virus envelope protein. Cell Rep 2017 (published online Oct 31)
Goldfarb IT, Jaffe E, Lyerly AD. Responsible care in the face of shifting recommendations and imperfect diagnostics for Zika virus. JAMA 2017 (published online Oct 27)
Griffin I, Zhang G, Fernandez D, et al. Epidemiology of pediatric Zika virus infections. Pediatrics 2017 (published online Nov 1)
Epelboin Y, Talaga S, Epelboin L, et al. Zika virus: an updated review of competent or naturally infected mosquitoes. PLoS Negl Trop Dis 2017 Nov 16;11(11):e0005933
Fuller TL, Calvet G, Estevam CG, et al. Behavioral, climatic, and environmental risk factors for Zika and Chikungunya virus infections in Rio de Janeiro, Brazil, 2015-16. PLoS One 2017 Nov 16;12(11):e0188002
Ho HJ, Wong JGX, Kyaw WM, et al. Diagnostic accuracy of parameters for Zika and dengue virus infections, Singapore. Emerg Infect Dis 2017 (published online Nov 2)
Hoyt AT, Canfield MA, Langlois PH, et al. Pre-Zika descriptive epidemiology of microcephaly in Texas, 2008–2012. Birth Defects Res 2017 (published online Nov 24)
Jurado KA, Yockey LJ, Wong PW, et al. Antiviral CD8 T cells induce Zika-virus-associated paralysis in mice. Nat Microbiol 2017 (published online Nov 20)
Kroelinger CD, Romero L, Lathrop E, et al. State and local implementation strategies for increasing access to contraception during zika preparedness and response — United States, September 2016. (Meeting summary) MMWR 2017 Nov 10;66(44):1230-5
Landais A, Audrey Cesaire A, Fernandez M, et al. Zika vasculitis: a new cause of stroke in children? (Letter) J Neurol Sci 2017 (published online Oct 27)
Lee CT, Greene SK,  Baumgartner J, et al. Disparities in Zika virus testing and incidence among women of reproductive age — New York City, 2016. J Public Health Manag Pract 2017 (published online Oct 27)
Lourenco-de-Oliveira R, Marques JT, Sreenu VB, et al. Culex quinquefasciatus mosquitoes do not support replication of Zika virus. J Gen Virol 2017 (published online Oct 27)
Musso D, Bossin H, Mallet HP, et al. Zika virus in French Polynesia 2013-14: anatomy of a completed outbreak. Lancet Infect Dis 2017 (published online Nov 14)
Nogueira ML, Junior NRRN, Estofolete CF, et al. Adverse birth outcomes associated with Zika virus exposure during pregnancy in Sao Jose do Rio Preto, Brazil. Clin Microbiol Infect 2017 (published online Nov 10)
Orioli IM, Dolk H, Lopez-Camelo JS, et al. Prevalence and clinical profile of microcephaly in South America pre-Zika, 2005-14: prevalence and case-control study. BMJ 2017 Nov 21;359:j5018
Ortiz MR, Le NK, Sharma V, et al. Post-earthquake Zika virus surge: disaster and public health threat amid climatic conduciveness. Sci Rep 2017 (published online Nov 13)
Netto EM, Moreira-Sotoc A, Pedroso C, et al. High Zika virus seroprevalence in Salvador, northeastern Brazil limits the potential for further outbreaks. mBio 2017 (published online Nov 14)
Rodriguez-Diaz CE, Garriga-Lopez A, Malave-Rivera SM, et al. Zika virus epidemic in Puerto Rico: health justice too long delayed. Int J Infect Dis 2017 (published online Nov 15)
Rosenfeld AB, Doobin DJ, Warren AL, et al. Replication of early and recent Zika virus isolates throughout mouse brain development. Proc Natl Acad Sci USA 2017 (published online Oct 31)
Russell S, Ryff K, Gould C, et al. Detecting local Zika virus transmission in the continental United States: a comparison of surveillance strategies. PLoS Curr 2017 Nov 22
Sariol CA, Nogueira ML, Vasilakis N. A tale of two viruses: does heterologous flavivirus immunity enhance Zika disease? Trends Microbiol 2017 (published online Nov 6)
Shiryaev SA, Mesci P, Pinto A, et al. Repurposing of the anti-malaria drug chloroquine for Zika Virus treatment and prophylaxis. Sci Rep 2017 (published online Nov 17)
Simkins J, Anjan S, Morillas-Rodriquez JA, et al. Screening for Zika virus in deceased organ donors in Florida. Am J Transplant 2017 (published online Nov 8)
Song S, Li Y, Fu S, et al. Could Zika virus emerge in mainland China? Virus isolation from nature in Culex quinquefasciatus, 2016. Emerg Microbes Infect 2017 (published online Nov 1)
Tabata T, Petitt M, Puerta-Guardo H, et al. Zika virus replicates in proliferating cells in explants from first-trimester human placentas, potential sites for dissemination of infection. J Infect Dis 2017 (published online Nov 2)
Turner LH, Kinder JM, Adrienne Wilburn A, et al. Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection. PLoS Pathog 2017 Nov 16;13(11):e1006684
Vanchiere JA, Ruiz JC, Brady AG, et al. Experimental Zika virus infection of neotropical primates. Am J Trop Med Hyg 2017 (published online Nov 27)
Wen J, Ngono AE, Regla-Nava JA, et al. Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge. Nat Commun 2017 (published online Nov 13)



Latest Cases & General Information

Zika virus (CDC landing page)
Latest Zika situation reports (WHO)
Zika virus infections and complications called Public Health Emergency of International Concern (WHO, Feb 1, 2016)
Zika virus disease, frequently asked questions about Zika virus (WHO Emergencies Preparedness, Response)
Zika virus infection (PAHO/WHO landing page)

Maps

Current Zika transmission (ECDC)
2016 Zika outbreak timeline map (HealthMap)
Pacific Disaster Center maps (updated periodically)
Zika in the United States, explained in 9 maps (Vox, Aug 4, 2016)
Zika cases in the United States (New York Times, Jul 29, 2016)
Maps predict possible Zika hot spots (USA Today, Apr 28, 2016)
Mapping global environmental suitability for Zika virus (eLife study, Apr 19, 2016)

Latest News & Commentary

Most recent CIDRAP News coverage (updated frequently)
Drones distribute swarms of sterile mosquitoes to stop Zika and other diseases (IEEE Spectrum, Nov 20)
Assessing Zika risk in international travelers (Allison Walker, PhD, MPH, commentary on Medscape, Nov 20)
Drug used to treat malaria could help fight Zika’s damaging effects (CBS Miami, Nov 20)
Florida confirms second local Zika virus infection for 2017 (AP, Nov 17)
A plan to develop a Zika vaccine runs into controversy, as questions swirl about price and conflicts of interest (Stat, Nov 17)
Evolution of neurovirulent Zika virus (Commentary in Science, Nov 17)
Birth rate in Brazil falls to 26-year low after Zika crisis (Medical Xpress, Nov 14)
To find an effective Zika vaccine, we must include pregnant women in the trials (Commentary in The Hill, Nov 12)
Some good news, as a Zika-exposed baby turns one (WAMU, Nov 9)
US government approves 'killer' mosquitoes to fight disease (Nature News, Nov 6)
Although the number of Zika cases has fallen, the virus is unlikely to vanish (Washington Post, Nov 4)
Sexually transmitted case of Zika confirmed in Miami-Dade (Miami Herald, Nov 3)
The forgotten mothers and babies of Zika (CNN, Nov 2)
Zika virus has always been neurotropic (Virology blog, Nov 2)

World Health Organization (WHO)

General Information

The history of Zika virus (timeline)
WHO podcast episodes 2017
(updated Mar 29, 2017)
Zika virus and potential complications: questions and answers
(Mar 10, 2017)
Zika: then, now, and tomorrow (Feb 2, 2017)
Zika: we must be ready for the long haul
(Feb 1, 2017, commentary from director-general Margaret Chan)
WHO Zika virus research agenda (Oct 26, 2016)
Dispelling rumours around Zika and complications (updated Sep 12, 2016)
One year into the Zika outbreak: how an obscure disease became a global health emergency
(May 5, 2016)
WHO involvement in Zika R&D
(Feb 8, 2016)
Zika virus outbreaks in the Americas (WHO Weekly Epidemiological Record, Nov 6, 2015)

Blood Supply

Maintaining a safe and adequate blood supply during Zika virus outbreaks, interim guidance (Feb 19, 2016)

Case Definitions

Zika virus disease: interim case definition (Feb 12, 2016)

Congenital Zika Syndrome/Fetal Infection

Fifth meeting of the Emergency Committee under the International Health Regulations (2005) regarding microcephaly, other neurological disorders and Zika virus (Nov 18, 2016)
Zika causality statement
(updated Sep 7, 2016)
Assessment of infants with microcephaly in the context of Zika virus: interim guidance
(updated Aug 30, 2016)
Surveillance for Zika virus infection, microcephaly and Guillain-Barre syndrome: interim guidance
(Apr 7, 2016)
Zika situation report: Neurological syndrome and congenital abnormalities
(Feb 5, 2016)

Diagnostics

Update on Zika diagnostic tests and WHO’s related activities (Feb 2, 2017, PLoS Negl Trop Dis policy platform)
Laboratory testing for Zika virus infection: interim guidance
(Mar 23, 2016)
WHO and experts prioritize vaccines, diagnostics and innovative vector control tools for Zika R&D (Note for media, Mar 9, 2016)

Epidemiology

WHO confirms Zika virus strain imported from the Americas to Cabo Verde (May 20, 2016)
Zika virus infection — Argentina and France
(Disease Outbreak News, Mar 7, 2016)

Neurologic Manifestations

Fifth meeting of the Emergency Committee under the International Health Regulations (2005) regarding microcephaly, other neurological disorders and Zika virus (Nov 18, 2016)
Guillain-Barre syndrome: fact sheet
(updated October 2016)
Identification and management of Guillain-Barre syndrome in the context of Zika virus: interim guidance
(updated Aug 22, 2016)
Guillain-Barre syndrome
United States of America (Disease Outbreak News, Mar 21, 2016)
Guillain-Barre syndrome — France - French Polynesia (Disease Outbreak News, Mar 7, 2016)
Zika situation report: Neurological syndrome and congenital abnormalities (Feb 5, 2016)
Guillain-Barre syndrome — El Salvador (Disease Outbreak News, Jan 21, 2016)

Outbreak Dynamics, Control

Disease Outbreak News updates
Zika situation report: Zika and potential complications (Feb 12, 2016)

Pregnancy/Breastfeeding

Breastfeeding in the context of Zika virus: interim guidance (updated Jun 29, 2016)
Pregnancy management in the context of Zika virus infection: interim guidance update
(updated May 13, 2016)

Recommendations/Responses

Fifth meeting of the Emergency Committee under the International Health Regulations (2005) regarding microcephaly, other neurological disorders and Zika virus (Nov 18, 2016)
Zika strategic response plan
(quarterly update, Oct 27, 2016)
Zika: strategic response plan (Jun 17, 2016)
Zika virus outbreak global response: interim report (May 27, 2016)
Zika outbreak: WHO's global emergency response plan (updated Jul 15, 2016)

Risk

Zika virus expected to spread in Europe in late spring and summer: overall risk low to moderate (May 18, 2016)
Zika virus vectors and risk of spread in the WHO European Region (Mar 18, 2016)
Zika virus risk assessment in the WHO African Region (February 2016)

Sexual and Other Non-Vector Transmission

Zika and sexual transmission (Q&A, updated Mar 10, 2017)
Prevention of sexual transmission of Zika virus: interim guidance (updated Sep 6, 2016)

Tools

WHO toolkit for the care and support of people affected by complications associated with Zika virus(Jun 18, 2017)
Zika open (Bull World Health Organ papers posted in the context of the Public Health Emergency of International Concern)

Travelers

Brazil — health advice for travellers to the 2016 Summer Olympic and Paralympic Games (updated Sep 6, 2016)
WHO public health advice regarding the Olympics and Zika virus (news release, May 28, 2016)

Vector Control/Mosquito Transmission

Vector control operations framework for Zika virus: operations framework (May 30, 2016)
Zika virus vectors and risk of spread in the WHO European Region (Mar 18, 2016)

Pan American Health Organization (PAHO)

General Information

Zika virus infection (landing page)
Zika research projects list (updated continuously)
PAHO Executive Committee briefed on Zika outbreak, advances new arbovirus control strategy (updated Mar 22, 2017)
Zika a year later: how a new virus took the Americas by surprise (updated Mar 22, 2017)
The Zika Virus outbreak continues one year after the global emergency (Feb 1, 2017)
2016: the year Zika evolved from an emergency into a long-term public health challenge (Dec 29, 2016)
PAHO director: Fight against Zika will be a ‘marathon’ (Nov 14, 2016)
Zika epidemic shows value of regional health collaboration (Sep 26, 2016)
PAHO launches database that gathers worldwide Zika virus research (updated Jun 20, 2016)
Questions and answers on vector control for Zika virus (Mar 24, 2016)
PAHO statement on Zika virus transmission and prevention (updated Feb 2, 2016)
PAHO activities on Zika prevention and control (Jan 27, 2016)
Question and Answers: Zika and pregnancy (updated Mar 25, 2016)
Community work: a key to Zika prevention in Colombia (updated Mar 15, 2016)

Congenital Zika Syndrome/Fetal Infection

PAHO/WHO updates the characterization of Zika congenital syndrome (Jul 22, 2016)
Scientists probe Zika congenital syndrome at Brazil meeting (Jul 21, 2016)
Scientists call for intensified research on Zika and microcephaly (updated Mar 7, 2016)
Neurological syndrome, congenital malformations, and Zika virus infection (Epidemiologic update, Jan 17, 2016)
Neurological syndrome, congenital malformations, and Zika virus infection. Implications for public health in the Americas (Epidemiologic alert, Dec 1, 2015)

Diagnostics

PAHO aims for faster diagnosis, more integration in combat against Zika, Dengue and Chikungunya viruses (updated Feb 18, 2016)

Epidemiology

Zika epidemiological update (updated May 25, 2017)
Zika virus infection (Epidemiologic alert, May 7, 2015)
Neurological syndrome, congenital malformations, and Zika virus infection (Epidemiologic update, Jan 17, 2016)
Neurological syndrome, congenital malformations, and Zika virus infection. Implications for public health in the Americas (Epidemiologic alert, Dec 1, 2015)

Neurologic Manifestations

Neurological syndrome, congenital malformations, and Zika virus infection (Epidemiologic update, Jan 17, 2016)
Neurological syndrome, congenital malformations, and Zika virus infection. Implications for public health in the Americas (Epidemiologic alert, Dec 1, 2015)

Recommendations/Responses

WHO and PAHO initiative to support 17 new research proposals on Zika in seven countries in Latin America and the Caribbean (Feb 23, 2017)
Cartoon Network, PAHO and UNICEF launch second phase of campaign to educate kids about preventing Zika (Feb 16, 2017)
Latin American countries conduct surveys to identify gaps in knowledge about Zika, with support from PAHO/WHO (Aug 12, 2016)
Zika ethics consultation: ethics guidance on key issues raised by the outbreak (May 23, 2016)
Cartoon Network joins PAHO, UNICEF to educate kids about preventing Zika (May 19, 2016)

Risk

Zika risk communication, community engagement focus of new prevention efforts by CDC, CDC Foundation, PAHO in U.S. Territories and the Americas (May 18, 2016)

Vector Control/Mosquito Transmission

Health leaders discuss action against mosquito-borne viruses such as Zika and dengue (Oct 21, 2016)
Caribbean Mosquito Awareness Week launched to raise awareness on preventing Zika (May 9, 2016)
Communities urged to clean up mosquito breeding sites to prevent Zika, during Vaccination Week in the Americas (Apr 28, 2016)
Scientists studying intensified vector control measures to combat Zika, dengue and chikungunya in the Americas (Mar 11, 2016)

Virus Detection

Zika virus surveillance intensifying in the Americas, but burden of disease still unclear (updated Mar 29, 2016)
PAHO, laboratories set guidelines to identify, confirm Zika virus (Feb 26, 2016)
PAHO aims for faster diagnosis, more integration in combat against Zika, Dengue and Chikungunya viruses (updated Feb 18, 2016)
As the Zika virus spreads, PAHO advises countries to monitor and report birth anomalies and other suspected complications of the virus (updated Feb 4, 2016)

US Centers for Disease Control and Prevention (CDC)

General Information

Question and answers: Zika virus infection (Zika) and pregnancy
Questions and answers for pediatric healthcare providers: Infants and Zika virus infection

Facts about microcephaly

Fact sheets and posters
(in multiple languages)
Zika virus microsite (for info sharing and tracking developments)
Zika data repository on Github

Zika and animals (Jun 29, 2017)
Zika: What you need to know (updated Jun 29, 2017)
Information for parents
(updated Jun 21, 2016)
Zika virus: information for clinicians
(slide set, Jun 13, 2016)
CDC director addresses National Press Club
(transcript, May 26, 2016—most is on Zika)
Symptoms
(updated May 1, 2017)
Zika virus 101
(video, Apr 7, 2017)
Prevention
(updated Jan 9, 2017)
5 things you really need to know about Zika
(Public Health Matters Blog, Feb 24, 2016)
Zika virus — what clinicians need to know
(Jan 26, 2016)
Zika virus —10 public health achievements in 2016 and future priorities
(updated Jan 5, 2017, MMWR report)
CDC highlights significant contributions in the fight against Zika in 2016
(Dec 30, 2016)
Information for specific groups (updated Dec 15, 2016)
US Zika Pregnancy Registry: what parents need to know (Apr 22, 2016)
Zika Action Plan Summit (Apr 1, 2016)
National Zika summit focused on coordinated U.S. response (news release, Apr 1, 2016)
Information for parents about Zika virus
(Mar 19, 2016)

Congenital Zika Syndrome/Fetal Infection

Characteristics of dysphagia in infants with microcephaly caused by congenital Zika virus infection, Brazil, 2015. (Jun 12, 2017)
Implementing CDC guidance for infant and placental Zika virus testing and infant head ultrasound
(May 5, 2017)
About 1 in 10 U.S. pregnant women with confirmed Zika infection had a fetus or baby with birth defects in 2016 (updated Apr 6, 2017)
CDC study estimates 20-fold increase in certain types of birth defects in pregnancies with possible Zika infection compared with pre-Zika years
(Mar 2, 2017)
Tips for communicating with your baby's doctor or healthcare provider
(Jan 17, 2017)
What to know: If your baby was born with congenital Zika syndrome (Dec 20, 2016)
CDC releases preliminary estimates of birth defects following Zika virus infection in pregnancy
(Dec 15, 2016)
Study finds Zika virus replicates and persists in fetal brains and placentas (Dec 13, 2016)
Preliminary report of microcephaly potentially associated with Zika virus infection during pregnancy — Colombia, January-November 2016 (Dec 9, 2016, MMWR report)
Zika update: clinical laboratory testing and care of infants with congenital Zika virus infection
(COCA call, Aug 23, 2016)
Interim guidance for the evaluation and management of infants with possible congenital Zika virus infection — United States, August 2016. (Aug 19, 2016, update)
Support for families of newborns affected by Zika (Aug 19, 2016)
CDC concludes Zika causes microcephaly and other birth defects (media statement, Apr 13, 2016)

Diagnostics

Understanding Zika virus test results (updated May 10, 2017)
Testing for Zika virus (including for pregnancy, updated Nov 8, 2016)
Zika update: clinical laboratory testing and care of infants with congenital Zika virus infection (COCA call, Aug 23, 2016)
Zika diagnostic tools, testing algorithms, and interpretation guidance (Jun 13, 2016)
Diagnostic testing of urine specimens for suspected Zika virus infection (HAN advisory, May 25, 2016)
Recognizing, managing, and reporting Zika virus infections in travelers returning from Central America, South America, the Caribbean, and Mexico (Health Advisory, Jan 15, 2016)
Revised diagnostic testing for Zika, chikungunya, and dengue viruses in US Public Health Laboratories (memo, Jan 7, 2016)
CDC scientists use AMD methods to develop diagnostic tools for Zika virus (Feb 3, 2016, fact sheet)

Epidemiology

CDC supporting Texas investigation of possible local Zika transmission (Nov 28, 2016)
Florida investigation links four recent Zika cases to local mosquito-borne virus transmission (Jul 29, 2016)
Zika infections increasing rapidly in Puerto Rico (Jul 29, 2016)
Possible Zika virus infection among pregnant women — United States and territories, May 2016
(MMWR report, May 20, 2016)

Funding

CDC awards nearly $184 million to continue the fight against Zika (Dec 22, 2016)
CDC announces supplemental funding opportunity for continued Zika response in 2017
(Oct 21, 2016)
CDC awards $13 million to establish the first Vector Control Unit in Puerto Rico
(Sep 27, 2016)
CDC awards $2.4 million to five jurisdictions to fight Zika (Sep 2, 2016)
CDC awards $6.8 million to partners to support Zika response (Aug 24, 2016)
CDC continues to support Florida in response to Zika outbreak (Aug 24, 2016)
CDC awards $16 million to states and territories to fight Zika
(Aug 2, 2016)
CDC awards $60 million to help states and territories battle Zika (Jul 21, 2016)
CDC awards funds for states and territories to prepare for Zika (Jul 1, 2016)

Guidance

CDC updates Zika guidance for Miami-Dade County, Florida (updated Jun 30, 2017)
Implementing CDC guidance for infant and placental Zika virus testing and infant head ultrasound
(May 5, 2017)
CDC updates guidance on interpretation of Zika testing results for pregnant women
(May 5, 2017)
CDC updates Zika travel guidance for pregnant women to not travel to any area with Zika risk
(Mar 10, 2017)
CDC adds 4 countries to interim travel guidance related to Zika virus
(Mar 10, 2017)
CDC issues Zika virus guidance for Brownsville, Texas (Dec 14, 2016)
CDC updates Zika guidance for South Miami Beach (FL) area
(Dec 9, 2016)
CDC updates guidance for Little River (FL) area with active Zika transmission (Dec 2, 2016)
CDC updates guidance for Miami Beach (FL) area with active Zika transmission (Nov 22, 2016)
Guidance for U.S. laboratories testing for Zika virus infection
(updated Nov 16, 2016)
Zika virus response planning: interim guidance for district and school administrators in the continental United States and Hawaii (Oct 20, 2016)
CDC updates guidance related to local Zika transmission in Miami-Dade County, Florida (Oct 19, 2016)
CDC updates guidance for pregnant women and women and men of reproductive age for Zika virus infection related to the ongoing investigation of local mosquito-borne Zika virus transmission in Miami-Dade County, Florida
(HAN notice, Oct 19, 2016)
CDC updates interim guidance for pre-pregnancy counseling and prevention of sexual transmission of Zika (Sep 30, 2016)
CDC updates guidance for travel and testing of pregnant women and women of reproductive age for Zika virus infection related to the ongoing investigation of local mosquito-borne Zika virus transmission in Miami-Dade County, Florida
(HAN notification, Sep 20, 2016)
CDC updates guidance for Wynwood (FL) neighborhood with active Zika transmission (Sep 19, 2016)
CDC expands guidance for travel and testing of pregnant women, women of reproductive age, and their partners for Zika virus infection related to mosquito-borne Zika virus transmission in Miami-Dade, Florida
(HAN advisory, Aug 19, 2016)
Interim guidance for the evaluation and management of infants with possible congenital Zika virus infection — United States, August 2016. (Aug 19, 2016, update)
Resources and guidance for healthcare providers caring for infants affected by Zika virus (Aug 19, 2016)
CDC issues travel guidance related to Miami neighborhood with active Zika spread (Aug 1, 2016)
CDC guidance for travel and testing of pregnant women and women of reproductive age for Zika virus infection related to the investigation for local mosquito-borne Zika virus transmission in Miami-Dade and Broward Counties, Florida (Health Alert Network notice, Aug 1, 2016)
CDC issues updated Zika recommendations: interim guidance for healthcare providers caring for pregnant women with possible exposure to Zika virus; interim guidance for the prevention of sexually transmitted Zika virus (Jul 25, 2016)
Interim guidance for interpretation of Zika virus antibody test results
(MMWR report, May 31, 2016)
Interim guidance for protecting workers from occupational exposure to Zika virus (CDC/OSHA, Apr 22, 2016)
Interim guidance for prevention of sexual transmission of Zika virus — United States, 2016
. (MMWR, Mar 25, 2016)
Interim guidance for health care providers caring for women of reproductive age with possible Zika virus exposure — United States, 2016. (MMWR, Mar 25, 2016)
Biosafety guidance for transportation of specimens and for work with Zika virus in the laboratory (Mar 15, 2016)
Zika virus risk-based preparedness and response guidance for states (Mar 9, 2016)
CDC encourages following guidance to prevent sexual transmission of Zika virus (media statement, Feb 23, 2016)

Neurologic Manifestations

Facts about microcephaly
About 1 in 10 U.S. pregnant women with confirmed Zika infection had a fetus or baby with birth defects in 2016
(updated Apr 6, 2017)
CDC study estimates 20-fold increase in certain types of birth defects in pregnancies with possible Zika infection compared with pre-Zika years (Mar 2, 2017)
What to know: If your doctor suspects microcephaly during pregnancy (Dec 20, 2016)
Preliminary report of microcephaly potentially associated with Zika virus infection during pregnancy — Colombia, January-November 2016 (Dec 9, 2016, MMWR report)
CDC concludes Zika causes microcephaly and other birth defects (media statement, Apr 13, 2016)
Increase in reported prevalence of microcephaly in infants born to women living in areas with confirmed Zika virus transmission during the first trimester of pregnancy — Brazil, 2015
(MMWR, Mar 8, 2016)

Outbreak Dynamics, Control

CDC, Miami-Dade and Miami Beach collaborate and make progress on better understanding and stopping the Zika outbreak (Oct 27, 2016)
CDC working with Florida to respond to new active Zika transmission area in Miami-Dade County (Oct 14, 2016)
CDC works with Florida as Miami Beach active Zika transmission area expands
(Sep 17, 2016)
Additional area of active Zika transmission identified in Miami Beach (Aug 19, 2016)

Pregnancy/Breastfeeding

Question and answers: Zika virus infection (Zika) and pregnancy
Testing pregnant women
(updated Jun 1, 2017)
CDC updates guidance on interpretation of Zika testing results for pregnant women (May 5, 2017)
Zika virus: protecting pregnant women and babies
(digital press kit, Apr 4, 2017)
CDC updates Zika travel guidance for pregnant women to not travel to any area with Zika risk
(Mar 10, 2017)
Zika virus and pregnancy
(grand round presentation, Jan 30, 2017)
Zika virus testing: For pregnant women who may have been exposed to Zika 2-12 weeks ago (Jan 10, 2017)
Zika virus testing: For pregnant women living in an area with Zika
(Jan 10, 2017)
Zika virus testing: For pregnant women who may have been exposed to Zika within the past 2 weeks
(Jan 10, 2017)
Evidence that microcephaly risk is highest among pregnant women infected early in pregnancy (Dec 9, 2016)
Testing for Zika virus (including for pregnancy, updated Nov 8, 2016)
CDC updates guidance for pregnant women and women and men of reproductive age for Zika virus infection related to the ongoing investigation of local mosquito-borne Zika virus transmission in Miami-Dade County, Florida (HAN notice, Oct 19, 2016)
CDC updates guidance for travel and testing of pregnant women and women of reproductive age for Zika virus infection related to the ongoing investigation of local mosquito-borne Zika virus transmission in Miami-Dade County, Florida (HAN notification, Sep 20, 2016)
CDC expands guidance for travel and testing of pregnant women, women of reproductive age, and their partners for Zika virus infection related to mosquito-borne Zika virus transmission in Miami-Dade, Florida (HAN advisory, Aug 19, 2016)
CDC guidance for travel and testing of pregnant women and women of reproductive age for Zika virus infection related to the investigation for local mosquito-borne Zika virus transmission in Miami-Dade and Broward Counties, Florida (Health Alert Network notice, Aug 1, 2016)
Pregnant women: how to protect yourself (updated Jul 28, 2016)
CDC issues updated Zika recommendations: interim guidance for healthcare providers caring for pregnant women with possible exposure to Zika virus; interim guidance for the prevention of sexually transmitted Zika virus (Jul 25, 2016)
CDC begins reporting pregnancy and birth outcomes of women affected by Zika virus during pregnancy
(Jun 16, 2016)
CDC changes reporting of numbers of pregnant women affected by Zika virus (May 20, 2016)
The Strategic National Stockpile's unique role in Zika prevention (Public Health Matters Blog, May 9, 2016)
Zika and pregnancy: what you should know (updated Apr 1, 2016)
Zika and sex: Information for pregnant women living in areas with Zika (Fact sheet, Mar 14, 2016)
For pregnant women in areas with Zika: Protect your pregnancy (Fact sheet, Mar 10, 2016)
Increase in reported prevalence of microcephaly in infants born to women living in areas with confirmed Zika virus transmission during the first trimester of pregnancy — Brazil, 2015 (MMWR, Mar 8, 2016)
Zika virus infection among U.S. pregnant travelers — August 2015–February 2016. (MMWR, Feb 26, 2016)

Recommendations/Responses

Advice for people living in or traveling to South Florida (updated Jun 2, 2017)
Guidance for areas with a previous Zika cautionary (yellow) designation in the continental United States and Hawaii
(Jun 1, 2017)
CDC Zika sustainment strategy presentation: overview
(May 10, 2017)
CDC Zika interim response plan
(updated May 5, 2017)
CDC and the Instituto Nacional de Salud of Colombia collaborate to understand long-term effects of Zika virus infection during pregnancy
(Sep 2, 2016)
CDC issues updated Zika recommendations: interim guidance for healthcare providers caring for pregnant women with possible exposure to Zika virus; interim guidance for the prevention of sexually transmitted Zika virus (Jul 25, 2016)
U.S. Centers for Disease Control and Prevention and Environmental Protection Agency urge Commonwealth of Puerto Rico to consider aerial spraying as part of integrated mosquito control to reduce Zika-associated birth defects (Jul 6, 2016)
CDC recommendations for subsequent Zika IgM antibody testing (Health Alert Network, Jun 21, 2016)
Zika: CDC draft interim response plan (Jun 14, 2016)
CDC issues advice for travel to the 2016 Summer Olympic Games (Feb 26, 2016)

Risk

CDC identifies potential risk of Zika virus transmission since June 15, 2016, in Miami-Dade, Broward, and Palm Beach counties (Mar 13, 2017)
Evidence that microcephaly risk is highest among pregnant women infected early in pregnancy (Dec 9, 2016)
Healthcare exposure to Zika and infection control (Oct 21, 2016)
Zika virus risk-based preparedness and response guidance for states
(Mar 9, 2016)

Sexual and Other Non-Vector Transmission

Sexual transmission and prevention (updated Aug 2, 2017)
CDC assisting Utah investigation of Zika virus infection apparently not linked to travel (Jul 18, 2016)
First female-to-male sexual transmission of Zika virus infection reported in New York City (Jul 15, 2016)
Estimating contraceptive needs and increasing access to contraception in response to the Zika virus disease outbreak — Puerto Rico, 2016. (MMWR, Mar 25, 2016)
Interim guidance for prevention of sexual transmission of Zika virus — United States, 2016
. (MMWR, Mar 25, 2016)
Preventing transmission of Zika virus in labor and delivery settings through implementation of standard precautions — United States, 2016. (MMWR, Mar 22, 2016)
Zika and sex: Information for men with pregnant partners living in areas with Zika (Fact sheet, Mar 14, 2016)
Zika and sex: Information for pregnant women living in areas with Zika (Fact sheet, Mar 14, 2016)
Transmission of Zika virus through sexual contact with travelers to areas of ongoing transmission — continental United States, 2016
. (MMWR, Feb 26, 2016)
Update: Interim guidelines for prevention of sexual transmission of Zika virus — United States, 2016
(Health Alert Network advisory, Feb 23, 2016)
CDC encourages following guidance to prevent sexual transmission of Zika virus (media statement, Feb 23, 2016)

Serology

Prolonged IgM antibody response in people infected with Zika virus: implications for interpreting serologic testing results for pregnant women (Health Alert Network, May 5, 2017)

Tools

Fact sheets and posters (in multiple languages)
Toolkit for investigating possible local mosquito-borne transmission of Zika virus (May 5, 2017
Symptoms (updated May 1, 2017)
Healthcare provider toolkit: for obstetricians
(Feb 21, 2017)
Healthcare provider toolkit: for pediatricians (Feb 21, 2017)
Pregnancy & Zika testing Web tool (updated Jan 30, 2017)
Zika virus: a primer for nurses (grand round presentation, Jan 30, 2017)
Zika virus and pregnancy (grand round presentation, Jan 30, 2017)
Zika and infants: a primer
(grand round presentation, Jan 30, 2017)
Zika training for healthcare providers (updated Jan 18, 2017)
What to know: If your baby may have been affected by Zika but has no related health conditions at birth
(Dec 20, 2016)
What to know: If your baby was born with congenital Zika syndrome
(Dec 20, 2016)
What to know: If your doctor suspects microcephaly during pregnancy
(Dec 20, 2016)
Zika in the ED: how emergency care staff can take action (Nov 1, 2016, COCA call)
Zika is in your area: what to do (Aug 1, 2016)
Pregnant women: how to protect yourself (updated Jul 28, 2016)
Build your own Zika prevention kit (updated Jul 1, 2016)
Tools for health care providers (updated Mar 26, 2016)

Travelers

Travel health notices
Zika travel information
(updated Jun 29, 2017)
Advice for people living in or traveling to South Florida (updated Jun 2, 2017)
CDC adds 4 countries to interim travel guidance related to Zika virus
(Mar 10, 2017)
CDC updates Zika travel guidance for pregnant women to not travel to any area with Zika risk
(Mar 10, 2017)
CDC updates guidance for pregnant women and women and men of reproductive age for Zika virus infection related to the ongoing investigation of local mosquito-borne Zika virus transmission in Miami-Dade County, Florida (HAN notice, Oct 19, 2016)
CDC issues Zika special travel considerations for 11 Southeast Asian countries (Sep 29, 2016)
CDC updates guidance for travel and testing of pregnant women and women of reproductive age for Zika virus infection related to the ongoing investigation of local mosquito-borne Zika virus transmission in Miami-Dade County, Florida (HAN notification, Sep 20, 2016)
CDC expands guidance for travel and testing of pregnant women, women of reproductive age, and their partners for Zika virus infection related to mosquito-borne Zika virus transmission in Miami-Dade, Florida (HAN advisory, Aug 19, 2016)
CDC issues travel guidance related to Miami neighborhood with active Zika spread (Aug 1, 2016)
CDC guidance for travel and testing of pregnant women and women of reproductive age for Zika virus infection related to the investigation for local mosquito-borne Zika virus transmission in Miami-Dade and Broward Counties, Florida (Health Alert Network notice, Aug 1, 2016)
CDC models risk of Zika virus importation resulting from travel to the 2016 Olympic and Paralympic Games (Jul 13, 2016)
Revision to CDC's Zika travel notices: minimal likelihood for mosquito-borne Zika virus transmission at elevations above 2,000 meters. (MMWR, Mar 11, 2016)
Zika virus infection among U.S. pregnant travelers — August 2015–February 2016. (MMWR, Feb 26, 2016)
Transmission of Zika virus through sexual contact with travelers to areas of ongoing transmission — continental United States, 2016. (MMWR, Feb 26, 2016)
CDC issues advice for travel to the 2016 Summer Olympic Games
(Feb 26, 2016)
Recognizing, managing, and reporting Zika virus infections in travelers returning from Central America, South America, the Caribbean, and Mexico (Health Advisory, Jan 15, 2016)

Vector Control/Mosquito Transmission

CDC surveys find increase in the number of U.S. counties with Aedes aegypti and Aedes albopictus mosquitoes that can spread Zika (Jun 20, 2017)
Toolkit for investigating possible local mosquito-borne transmission of Zika virus
(May 5, 2017
CDC awards $13 million to establish the first Vector Control Unit in Puerto Rico (Sep 27, 2016)
Florida health officials report on response to Zika in Wynwood; evidence shows aerial spraying likely helped interrupt local transmission (Sep 23, 2016)
Florida investigation links four recent Zika cases to local mosquito-borne virus transmission (Jul 29, 2016)
U.S. Centers for Disease Control and Prevention and Environmental Protection Agency urge Commonwealth of Puerto Rico to consider aerial spraying as part of integrated mosquito control to reduce Zika-associated birth defects (Jul 6, 2016)
The Strategic National Stockpile's unique role in Zika prevention (Public Health Matters Blog, May 9, 2016)
Preparing for local mosquito-borne transmission of Zika virus — United States, 2016. (MMWR, Apr 1, 2016)
Zika, mosquitoes, and standing water (Public Health Matters Blog, Mar 22, 2016)
Revision to CDC's Zika travel notices: minimal likelihood for mosquito-borne Zika virus transmission at elevations above 2,000 meters. (MMWR, Mar 11, 2016)

Virus Detection

Testing pregnant women (updated Jun 1, 2017)
Implementing CDC guidance for infant and placental Zika virus testing and infant head ultrasound (May 5, 2017)
CDC updates guidance on interpretation of Zika testing results for pregnant women
(May 5, 2017)
CDC and Thailand partnership improves lab testing for Zika virus (Mar 27, 2017)
Guidance for U.S. laboratories testing for Zika virus infection (updated Nov 16, 2016)
Testing for Zika virus (including for pregnancy, updated Nov 8, 2016)
CDC continues to build US laboratory capacity to rapidly detect Zika virus infection (Sep 20, 2016)
Zika update: clinical laboratory testing and care of infants with congenital Zika virus infection (COCA call, Aug 23, 2016)
Collection and submission of specimens for Zika virus testing at time of birth (Aug 19, 2016)
Collection and submission of fetal tissues for Zika virus testing (Aug 19, 2016)
Triple testing: CDC works rapidly to develop unprecedented Zika test (Aug 16, 2016)
Diagnostic testing of urine specimens for suspected Zika virus infection (HAN advisory, May 25, 2016)
CDC changes reporting of numbers of pregnant women affected by Zika virus (May 20, 2016)
New CDC laboratory test for Zika virus authorized for emergency use by FDA (Feb 26, 2016)

Virus Traits/Structure/Mutations/Actions

Prolonged IgM antibody response in people infected with Zika virus: implications for interpreting serologic testing results for pregnant women (Health Alert Network, May 5, 2017)
Study finds Zika virus replicates and persists in fetal brains and placentas
(Dec 13, 2016)

Zika and Other Pathogens

West Nile to Zika: how one virus helped New York City prepare for another (Public Health Matters Blog, Sep 12, 2016)
Triple testing: CDC works rapidly to develop unprecedented Zika test
(Aug 16, 2016)
Revised diagnostic testing for Zika, chikungunya, and dengue viruses in US Public Health Laboratories
(memo, Jan 7, 2016)

Government of Canada

Zika virus (landing page)
Public health notice — Zika virus (Public Health Agency of Canada [PHAC])
Zika virus infection in the America (Travel health notice, PHAC)

European Centre for Disease Prevention and Control (ECDC)

General Information

Zika virus infection (landing page)
Current Zika virus transmission — list of countries: ECDC adaptation of WHO's Zika virus country classification scheme
(Jun 29, 2017)
Recent scientific findings based on literature reviewed after the ninth update of the ECDC Rapid Risk Assessment on Zika virus infection (19 October to 27 January 2017)
(Feb 6, 2017)
Recent scientific findings based on literature reviewed after the eighth update of the ECDC Rapid Risk Assessment on Zika virus infection (Oct 28, 2016)
Infographic: How is Zika virus transmitted? (Aug 26, 2016)
Zika virus and safety of substances of human origin (Jul 15, 2016)

Epidemiology

Outbreaks of Zika virus and complications potentially linked to the Zika virus infection (epidemiologic update, Jul 21, 2016)
Outbreaks of Zika virus and complications potentially linked to the Zika virus infection (epidemiologic update, Jun 23, 2016)
Outbreaks of Zika virus and complications potentially linked to the Zika virus infection
(Feb 4, 2016, epidemiologic update)

Neurologic Manifestations

The Zika epidemic and association to microcephaly and Guillain-Barre (updated risk assessment, Jul 11, 2016)
Microcephaly in Brazil potentially linked to the Zika virus epidemic, ECDC assesses the risk
(Nov 24, 2015)

Tools

Zika virus and safety of substances of human origin (Jul 15, 2016)

Recommendations/Responses

Preparing for Zika in the EU – policy briefing (Jun 26, 2016)
Zika virus disease epidemic: preparedness planning guide for diseases transmitted by Aedes aegypti and Aedes albopictus
(Apr 8, 2016)

Risk

The Zika epidemic and association to microcephaly and Guillain-Barre (updated risk assessment, Jul 11, 2016)
Accumulating evidence on Zika virus disease and potential link to severe outcomes
(Rapid risk assessment, Apr 12, 2016)
Microcephaly in Brazil potentially linked to the Zika virus epidemic, ECDC assesses the risk (Nov 24, 2015)
Zika virus infection outbreak, French Polynesia (Rapid risk assessment, updated Feb 14, 2014)

United Nations

A socio-economic impact assessment of the Zika virus in Latin America and the Caribbean: with a focus on Brazil, Colombia and Suriname (Apr 3, 2017)
Zika could end up costing Latin America and the Caribbean up to $18 billion, UN report finds
(Apr 6, 2017)
The human rights dimensions of Zika (commentary by Alexandra Phelan & Lawrence Gostin, Apr 4, 2016)

UNICEF

ZIKV diagnostics request for proposal launched; $10 million advance purchase commitment created (Feb 28, 2017)

Public Health England (PHE)

The characteristics, symptoms, diagnosis and epidemiology of Zika (landing page)

London School of Hygiene and Tropical Medicine

Web page

New Zealand Ministry of Health

Zika virus (landing page)
Zika virus: updated travel advice for pregnant women (Mar 1, 2016)

US National Institutes of Health (NIH)

Study to examine effects of Zika infection in Guatemalan infants and children (Jun 19, 2017)
Zika virus
(resource page)
Zika virus and older adults — what you need to know: tips from the National Institute on Aging (Nov 9, 2016)
NIH begins testing investigational Zika vaccine in humans (Aug 3, 2016)
NIH funds Zika virus study involving U.S. Olympic team (Jul 5, 2016)
NIH launches large study of pregnant women in areas affected by Zika virus (Jun 21, 2016)
Zika’s potential threat to world blood supply deserves study — and action (Jun 14, 2016)
Snapshots of life: portrait of Zika virus (NIH Director’s Blog, May 19, 2016)
Zika and birth defects: the evidence mounts (NIH Director’s Blog, Mar 15, 2016)
NIH seeks research applications to study Zika in pregnancy, developing fetus (Feb 5, 2016)
Zika virus: an emerging health threat (NIH Director’s blog, Jan 26, 2016)
Notice of NIAID's interest to highlight high-priority Zika virus (ZIKV) research areas (Jan 22, 2016)

US Health and Human Services (HHS)

General information

Zika virus health information resources (Disaster Information Management Research Center, updated daily)
Zika: resources at your fingertips (updated monthly)
Ensuring a coordinated response to Zika and other public health threats (Dec 5, 2016, ASPR Blog)
Here’s what you need to know about the Zika virus (Secretary Burwell, Jul 25, 2016)

Diagnostics

HHS funds development of Zika diagnostic test for use in doctors' offices (Aug 25, 2016)
HHS awards $7 million to OraSure to speed development of Zika diagnostic test
(Aug 23, 2016)
HHS awards $2.6 million to DiaSorin Group to develop rapid, high-capacity Zika diagnostic laboratory test
(Aug 22, 2016)
HHS helping lift key hurdle in the efforts to develop better Zika diagnostics (Apr 27, 2016)

Funding

Zika supplemental funding spend plan (Oct 26, 2016)
HHS awards $350,000 to American Academy of Pediatrics to help children affected by the Zika virus (Sep 8, 2016)
HHS funds development of Zika diagnostic test for use in doctors' offices (Aug 25, 2016)
HHS awards $7 million to OraSure to speed development of Zika diagnostic test
(Aug 23, 2016)
HHS awards $2.6 million to DiaSorin Group to develop rapid, high-capacity Zika diagnostic laboratory test
(Aug 22, 2016)
HHS awards more than $742,000 to health centers in American Samoa and the Virgin Islands to fight Zika (Jun 23, 2016)
HHS awards $5 million to Puerto Rico health centers to fight the spread of Zika virus (Apr 26, 2016)

Travelers

Take precautions to avoid Zika virus infection during trips abroad (ASPR Blog, Jul 6, 2016)

Vaccines

HHS accelerates development of mRNA-based Zika vaccine (Sep 7, 2016)
HHS calls on center for innovation to accelerate Zika vaccine development (Jun 27, 2016)

US Food and Drug Administration (FDA)

Zika Virus Response Updates from FDA (landing page)
FDA provides new tools for the development and proper evaluation of tests for detecting Zika virus infection (Aug 17, 2017)
ZIKV Detect IgM Capture ELISA by InBios International, Inc: FDA safety communication — wait for confirmatory test results before making patient management decisions (Dec 23, 2016)
Statement from Peter Marks, M.D., Ph.D., Director, FDA’s Center for Biologics Evaluation and Research (on blood screening, Jul 28, 2016)
FDA takes action against Zika virus (FDA Voice blog, Jul 12, 2016)
FDA allows use of investigational test to screen blood donations for Zika virus (news release, Mar 30, 2016)
FDA issues recommendations to reduce the risk of Zika virus transmission by human cell and tissue products (news release, Mar 1, 2016)
Emergency Use Authorization for Zika test (Feb 26, 2016)

US White House

Remarks by the president on the Zika virus (Jul 1, 2016)
The private sector is stepping up to combat the Zika virus—Congress should too (blog post, Jun 6, 2016)
Taking every step necessary, as quickly as possible, to protect the American people from Zika (blog post, Apr 6, 2016)
Preparing for and responding to the Zika virus at home and abroad (fact sheet, Feb 8, 2016)

US National Institute for Occupational Safety and Health (NIOSH)

Zika virus: key worker resources

US Congressional Research Service

Zika virus in Latin America and the Caribbean: U.S. policy considerations (Jun 29, 2016)
Zika response funding: request and congressional action (May 20, 2016)
Zika response funding: in brief (Apr 14, 2016)
Zika virus: global health considerations (CRS Insight, Feb 9, 2016)

US Government Accountability Office (GAO)

Preliminary observations on the Zika virus outbreak (Mar 2, 2016)

US Department of Agriculture (USDA)

USDA-ARS researchers are controlling mosquitoes naturally (video, Sep 26, 2017)

US Department of Defense

Walter Reed scientists test Zika vaccine candidate (Jun 9, 2016)
DoD adds funding to enhance Zika surveillance by military labs (May 16, 2016)

USAID

Combatting Zika and future threats: a grand challenge for development (Apr 13, 2016)

Institute of Medicine

Potential research priorities to inform public health and medical practice for domestic Zika virus (workshop brief, Feb 29, 2016)
Research priorities to inform public health and medical practice for domestic Zika Virus: a workshop (National Academies meeting video, Feb 16, 2016)

Public Health Emergency (US)

Promoting stress management for pregnant women during the Zika virus disease outbreak (Jun 29, 2016)

Resources in Affected Countries

CIDRAP-compiled list of health ministry links for affected countries

Resources from Journals, News Organizations

Zika virus detection and sexual transmission (Euro Surveill collection)
Zika reports (MMWR)
Zika virus (N Engl J Med)
Zika virus resource centre (Lancet)
Zika virus: free articles by discipline (Springer/Nature)
Zika virus resource center (Elsevier)
Zika virus: full coverage (USA Today)
Zika virus (BMJ)
Zika in 30 seconds: what you need to know today (STAT News)
Zika virus (Elsevier)
Zika virus outbreak (NBC News)
Reuters focus: the Zika virus
Zika virus disease (JAMA patient page, Jun 14, 2016)
Zika virus infection (compilation of Eurosurveillance articles on Zika)
Zika virus resources (PLoS Collections)
Zika virus resource page (Science Open)
Zika spotlight (Emerging Infectious Diseases articles, 2007-2016)
Zika virus in pregnancy: where to find useful guidance (BJOG)
Zika: a clinical guide (BMJ)

American Public Health Association (APHA)

New Zika virus chapter updates 'Control of Communicable Diseases Manual' (News release, May 11, 2016)

Association of Public Health Laboratories (APHL)

3 Zika tests explained (Aug 5, 2016)

American Medical Association (AMA)

Zika virus resource center

American Society for Microbiology (ASM)

Zika virus resources

American Congress of Obstetricians and Gynecologists (ACOG)

Zika virus
Practice advisory on Zika virus
(Aug 3, 2016, with SMFM)

American Academy of Pediatrics

Zika virus: psychosocial support videos (Apr 2017)

Wellcome Trust

The ethics of Zika trials in pregnancy (blog post, Apr 14, 2016)
Zika: Why now and what next? (video, Mar 1, 2016)
What we need to find out about Zika and pregnancy (Feb 18, 2016)
Zika: Q&A with the infectious disease expert (Feb 16, 2016)
Sharing data during Zika and other global health emergencies (Feb 10, 2016)
Zika virus outbreak in the Americas (Feb 1, 2016, blog post)
Taking action on Zika (Feb 2, 2016, blog post)
Zika: Q&A with the mapping expert (Feb 23, 2016)

Global Health Network, Fiocruz Institute (Brazil)

Zika infection

ReliefWeb

Zika virus infection: step-by-step guide to risk communication and community engagement (Jan 13, 2017)

March of Dimes

Zika Care Connect

New York University

U.S. public's perception of Zika risk: awareness, knowledge, and receptivity to public health interventions (Oct 28, 2016)

Johns Hopkins University

Hearing Notes: U.S. public health response to the Zika virus — continuing challenges (Bifurcated Needle blog, May 30, 2017)
The Zika virus: emerging data, uncertainty, and response (Bloomberg School of Public Health video, May 23, 2017)
What you need to know about Zika virus | Pregnancy and sexual transmission
(video, Apr 4, 2016)

UpToDate

Zika virus infection: an overview

Global Virus Network

GVN launches Zika Task Force (Feb 16, 2016)

MPHonline

Bitten: Zika virus 101 (infographic)

Center for Infectious Disease Modeling and Analysis (CIDMA)

A cost-effectiveness tool for informing policies on Zika control

Pregnancy Research Ethics for Vaccines, Epidemics, and New Technologies (PREVENT)

Pregnant women & the Zika virus vaccine research agenda: ethics guidance on priorities, inclusion, and evidence generation (Jun 2017)

National Association of County & City Health Officials (NACCHO)

Mosquito control capabilities in the U.S. (report, Oct 2017)
Shifting our approach to mosquito control capabilities in the U.S. (Oct 16, 2017)
Summer is here and so are the mosquitoes: why local vector control is key to combating Zika
(Jul 31, 2017)

Twitter 

CIDRAP (@CIDRAP)
PAHO-WHO (@pahowho)
World Health Organization (@WHO)
ECDC (@ECDC_EU)
Tom Frieden, MD, MPH (@DrFrieden)
Helen Branswell (@HelenBranswell)
Ian M Mackay, PhD (@MackayIM)
Lisa Schnirring (@lisaschnirring)
Michael Coston (@Fla_Medic)
Crawford Kilian (@crof)
Maryn McKenna (@marynmck)
Delthia Ricks (@DelthiaRicks)
Laurie Garrett (@Laurie_Garrett)
Martin Enserink (@martinenserink)
Jon Cohen (@sciencecohen)
Greg Folkers, MPH (@greg_folkers)
Maia Majumder, MPH (@maiamajumder)
Tara C. Smith, PhD (@aetiology)
Peter J. Hotez, MD (@PeterHotez)
Michael Edelstein, MbChB (@epi_michael)
Judy Stone, MD (@DrJudyStone)
Jeremy Farrar, MD (@JeremyFarrar)
PLoS Currents (@PLOSCurrents)

Selected Reading

2017

General Information

Ali S, Gugliemini O, Harber S, et al. Environmental and social change drive the explosive emergence of Zika virus in the Americas. PLoS Negl Trop Dis 2017 Feb 9;11(2):e0005135
Baud D, Gubler DJ, Schaub B, et al. An update on Zika virus infection. Lancet 2017 (published online Jun 21)
Bierle CJ, Fernandez-Alarcon C, Hernandez-Alvarado N, et al. Assessing Zika virus replication and the development of Zika-specific antibodies after a mid-gestation viral challenge in guinea pigs. PLoS One 2017 Nov 3;12(11):e0187720
Carlson CJ, Dougherty E, Boots M, et al. Consensus and conflict among ecological forecasts of Zika virus outbreaks in the United States. bioRxiv 2017 Nov 14
Cheema S, Maisonneuve P, Weber I, et al. Knowledge and perceptions about Zika virus in a Middle East country. BMC Infect Dis 2017 (published online Jul 26)
Coimbra BM, Coelho FC, Armstrong M, et al. Zika: an ongoing threat to women and infants. bioRxiv 2017 Nov 16
Colon-Gonzalez FJ, Peres CA, Bernardo CSS, et al. After the epidemic: Zika virus projections for Latin America and the Caribbean. PLoS Negl Trop Dis 2017 Nov 1;11(11):e0006007
He D, Gao D, Lou Y, et al. A comparison study of Zika virus outbreaks in French Polynesia, Colombia and the state of Bahia in Brazil. Sci Rep 2017 (published online Mar 21)
GAO (US Government Accountability Office).
Emerging infectious diseases: actions needed to address the challenges of responding to Zika virus disease outbreaks. GAO-17-445. May 23, 2017
Goldfarb IT, Jaffe E, Lyerly AD. Responsible care in the face of shifting recommendations and imperfect diagnostics for Zika virus. JAMA 2017 (published online Oct 27)
Hilgard J, Jamieson KH. Does a scientific breakthrough increase confidence in science? News of a Zika vaccine and trust in science. Sci Commun 2017 (published online Jul 25)
Krow-Lucal ER, Biggerstaff BJ, Staples JE. Estimated incubation period for Zika virus disease. Emerg Infect Dis 2017 (published online Mar 10)
Leder K, Grobusch MP, Gautret P, et al. Zika beyond the Americas: travelers as sentinels of Zika virus transmission. A GeoSentinel analysis, 2012 to 2016. PLoS One 2017 Oct 3;12(10):e0185689
Ortiz MR, Le NK, Sharma V, et al. Post-earthquake Zika virus surge: disaster and public health threat amid climatic conduciveness. Sci Rep 2017 (published online Nov 13)
Painter JE, Plaster AN, Tjersland DH, et al. Zika virus knowledge, attitudes, and vaccine interest among university students. Vaccine 2017 (published online Jan 6)
Prue CE, Roth Jr. JN, Garcia-Williams A, et al. Awareness, beliefs, and actions concerning Zika virus among pregnant women and community members — U.S. Virgin Islands, November-December 2016. MMWR 2017 Aug 31;66(34):909-13
Simkins J, Anjan S, Morillas-Rodriquez JA, et al. Screening for Zika virus in deceased organ donors in Florida. Am J Transplant 2017 (published online Nov 8)
Sorensen CJ, Borbor-Cordova MJ, Calvello-Hynes, et al. Climate variability, vulnerability and natural disasters: a case study of Zika virus in Manabi, Ecuador following the 2016 earthquake. GeoHealth 2017 (published online Oct 12)
Subissi L, Daudens-Vaysse E, Cassadou S, et al. Revising rates of asymptomatic Zika virus infections based on sentinel surveillance data from French overseas territories. Int J Infect Dis 2017 (published online Oct 25)
Yung CF, Tam CC, Rajadurai VS, et al. Rapid assessment Zika virus knowledge among clinical specialists in Singapore: a cross-sectional survey. PLoS Curr 2017 May 3
Wu Y, Cui X, Wu N, et al. A unique case of human Zika virus infection in association with severe liver injury and coagulation disorders. Sci Rep 2017 (published online Sep 12)

Antiviral Response/Candidates

Albulescu IC, Kovacikova K, Tas A, et al. Suramin inhibits Zika virus replication by interfering with virus attachment and release of infectious particles. Antiviral Res 2017 (published online Apr 28)
Best K, Guedj J, Madelain V, et al. Zika plasma viral dynamics in nonhuman primates provides insights into early infection and antiviral strategies. Proc Natl Acad Sci USA 2017 (published online Aug 1)
Boldescu V, Behnam MAM, Vasilakis N, et al. Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond. Nat Rev Drug Discov 2017 (published online May 5)
Costa VV, Del Sarto JL, Rocha RF, et al. N-methyl-d-aspartate (NMDA) receptor blockade prevents neuronal death induced by Zika virus infection. mBio 2017 Apr 25;8(2):e00350-17
Estoppey D, Lee CM, Janoschke, et al. The natural product cavinafungin selectively interferes with Zika and dengue virus replication by inhibition of the host signal peptidase. Cell Rep 2017 Apr 18:19(3):451-60
Fernandez E, Dejnirattisai W, Cao B, et al. Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection. Nat Immunol 2017 (published online Sep 25)
Ferreira AC, Zaverucha-do-Valle C, Reis PA, et al. Sofosbuvir protects Zika virus-infected mice from mortality, preventing short- and long-term sequelae. Sci Rep 2017 (published online Aug 25)
Ferreira MLB, de Brito CAA, Moreira AJP, et al. Guillain-Barre Syndrome, acute disseminated encephalomyelitis and encephalitis associated with Zika virus infection in Brazil: detection of viral RNA and isolation of virus during late infection. Am J Trop Med Hyg 2017 (published online Aug 28)
Hamel R, Ferraris P, Wichit S, et al. African and Asian Zika virus strains differentially induce early antiviral responses in primary human astrocytes. Infect Genet Evol 2017 (published online Jan 14)
Kazmirchuk T, Dick K, Burnside DJ, et al.
Designing anti-Zika virus peptides derived from predicted human-Zika virus protein-protein interactions. bioRxiv 2017 Jun 29
Li C, Deng YQ, Wang S, et al. 25-hydroxycholesterol protects host against Zika virus infection and its associated microcephaly in a mouse model. Immunity 2017 (published online Mar 14)
Li C, Zhu X,  Quanquin N, et al.
Chloroquine, a FDA-approved drug, prevents ZIKV infection and its associated congenital microcephaly in mice. EBioMedicine 2017 (published online Sep 28)
Magnani DM, Rogers TF, Beutler N, et al.
Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques. Sci Transl Med 2017 (published online Oct 4)
Magnani DM, Silveira CGT, Rosen BC, et al.
A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus.PLoS Negl Trop Dis 2017 Jun 12;11(6): e0005655
McArthur MA. Zika virus: recent advances towards the development of vaccines and therapeutics. Viruses 2017 (published online Jun 13)
Meertens L, Labeau A, Dejarnac O, et al. Axl mediates Zika virus entry in human glial cells and modulates innate immune responses. Cell Rep 2017 Jan 10;18(2):324-33
Metz SW, Gallichotte EN, Brackbill A, et al. In vitro assembly and stabilization of dengue and Zika virus envelope protein Homo-Dimers. Sci Rep 2017 (published online Jul 3)
Mounce BC, Cesaro T, Carrau L, et al. Curcumin inhibits Zika and chikungunya virus infection by inhibiting cell binding. Antiviral Res 2017 (published online Mar 24)
Mumtaz N, Jimmerson LC, Bushman LR, et al. Cell-line dependent antiviral activity of sofosbuvir against Zika virus. Antiviral Res 2017 (published online Sep 11)
Rausch K, Hackett BA, Weinbren NL, et al. Screening bioactives reveals nanchangmycin as a braod spectrum antiviral active against ZIka virus. Cell Rep 2017 Jan 17;18(3):804-15
Robbiani DF, Bozzacco L, Keeffe JR, et al. Recurrent potent human neutralizing antibodies to Zika virus in Brazil and Mexico. Cell 2017 (published online May 4)
Sacramento CQ, de Melo GR, de Freitas CS, et al. The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication. Sci Rep 2017 (published online Jan 18)
Salam AP, Rojek A, Dunning J, et al. Clinical trials of therapeutics for the prevention of congenital Zika virus disease: challenges and potential solutions. Ann Intern Med 2017 (published online Mar 21)
Saiz JC, Martín-Acebes MA.
The race to find antivirals for Zika virus. Antimicrob Agents Chemother 2017 (published online Mar 27)
Shiryaev SA, Mesci P, Pinto A, et al. Repurposing of the anti-malaria drug chloroquine for Zika Virus treatment and prophylaxis. Sci Rep 2017 (published online Nov 17)
Siddharta A, Pfaender S, Vielle NJ, et al. Virucidal activity of WHO-recommended formulations against enveloped viruses including Zika, Ebola and emerging coronaviruses. J Infect Dis 2017 (published online Feb 1)
Stein DR, Golden JW, Griffin BD, et al. Human polyclonal antibodies produced in transchromosomal cattle prevent lethal Zika virus infection and testicular atrophy in mice. Antiviral Res 2017 (published online Sep 8)
Smith DR, Hollidge B, Daye S, et al. Neuropathogenesis of Zika virus in a highly susceptible immunocompetent mouse model after antibody blockade of type I interferon. PLoS Negl Trop Dis 2017 Jan 9;11(1):e0005296
Wang J, Bardelli M, Espinosa DA, et al. A human bi-specific antibody against Zika virus with high therapeutic potential. Cell 2017 (published online Sep 21)
Wen J, Tang WW, Sheets N, et al. Identification of Zika virus epitopes reveals immunodominant and protective roles for dengue virus cross-reactive CD8+T cells. Nat Microbiol 2017 (published online Mar 13)
Yu Y, Deng YQ, Zou P, et al. A peptide-based viral inactivator inhibits Zika virus infection in pregnant mice and fetuses. Nat Commun 2017 (published online Jul 25)
Watanabe M, Jessie E. Buth JE, Vishlaghi N, et al. Self-organized cerebral organoids with human-specific features predict effective drugs to combat Zika virus infection. Cell Rep 2017 (published online Oct 10)

Blood Supply

Chevalier MS, Biggerstaff BJ, Basavaraju SV, et al. Use of blood donor screening data to estimate Zika virus incidence, Puerto Rico, April-August 2016. Emerg Infect Dis 2017 (published online Mar 6)
Galel SA, Williamson PC, Busch MP, et al. First Zika-positive donations in the continental United States. Transfusion 2017 (published online Feb 5)
Gake B, Vernet MA, Leparc-Goffart I, et al. Low seroprevalence of Zika virus in Cameroonian blood donors. Braz J Infect Dis 2017 (published online May 23)
Lum FM, Lin C, Susova OY, et al.
Sensitive detection of Zika virus antigen in patients' whole blood as an alternative diagnostic approach. J Infect Dis 2017 (published online Jun 6)
Mansuy JM, Mengelle C, Pasquier C, et al. Zika virus infection and prolonged viremia in whole-blood specimens. Emerg Infect Dis 2017 (published online Mar 3)
Rossini G, Gaibani P, Vocale C, et al. Comparison of Zika virus (ZIKV) RNA detection in plasma, whole blood and urine — case series of travel-associated ZIKV infection imported to Italy, 2016. J Infect 2017 (published online Jun 22)
Williamson PC, Linnen JM, Kessler DA, et al. First cases of Zika virus–infected US blood donors outside states with areas of active transmission. Transfusion 2017 (published online Feb 23)

Case Definitions

Braga JU, Bressan C, Dalvi APR, et al. Accuracy of Zika virus disease case definition during simultaneous dengue and chikungunya epidemics. PLoS One 2017 Jun 26;12(6):e0179725
Chow A, Ho H, Win MK, et al. Assessing sensitivity and specificity of surveillance case definitions for Zika virus disease. Emerg Infect Dis 2017 (published online Jan 24)
DeSilva M, Munoz FM, Sell E, et al. Congenital microcephaly: case definition & guidelines for data collection, analysis, and presentation of safety data after maternal immunisation. (Commentary) Vaccine 2017 (published online Nov 14)

Congenital Zika Syndrome/Fetal Infection

Acosta-Reyes J, Navarro E, Herrera MJ, et al. Severe neurologic disorders in 2 fetuses with Zika virus infection, Colombia. Emerg Infect Dis 2017 (published online Mar 15)
Adebanjo T, Godfred-Cato S, Viens L, et al. Update: Interim guidance for the diagnosis, evaluation, and management of infants with possible congenital Zika virus infection — United States, October 2017. MMWR 2017 Oct 20:66(41);1089-99
Adhikari EH, Nelson DB, Johnson KA, et al.Infant outcomes among women with ZIka virus infection during pregnancy: results of a large prenatal Zika screening program. Am J Obstet Gynecol 2017 (published online Jan 30)
Awadh A, Chughtai AA, Dyda A, et al. Does Zika virus cause microcephaly — applying the Bradford Hill viewpoints. PLoS Curr 2017 Feb 22
Benjamin I, Fernandez G, Figueira JV, et al. Zika virus detected in amniotic fluid and umbilical cord blood in an in vitro fertilization-conceived pregnancy in Venezuela. Fertil Steril 2017 (published online Apr 6)
Besnard M, Dub T, Geradin P. Outcomes for 2 children after peripartum acquisition of Zika virus infection, French Polynesia, 2013-2014. Emerg Infect Dis 2017 (published online May 9)
Chavali PL, Stojic L, Meredith LW, et al.
Neurodevelopmental protein Musashi 1 interacts with the Zika genome and promotes viral replication. Science 2017 (published online Jun 1)
Chibueze EC, Parsons AJQ, da Silva Lopes K, et al. Diagnostic accuracy of ultrasound scanning for prenatal microcephaly in the context of Zika virus infection: a systematic review and meta-analysis. Sci Rep 2017 (published online May 23)
Coelho AVC, Crovella S. Microcephaly prevalence in infants born to Zika virus-infected women: a systematic review and meta-analysis. Int J Mol Sci 2017 (published online Aug 5)
Coelho FC, Armstrong M, Saraceni V, et al. Can Zika account for the missing babies? bioRxiv 2017 Apr 12
Cragan JD, Mai CT, Petersen EE, et al. Baseline prevalence of birth defects associated with congenital Zika virus infection — Massachusetts, North Carolina, and Atlanta, Georgia, 2013-2014. MMWR 2017 Mar 3;66(8):219-22
Cunha AJLA, de Magalhaes-Barbosa MC, Lima-Setta F, et al. Microcephaly case fatality rate associated with Zika virus infection in Brazil: current estimates. Pediatr Infect Dis J 2017 May;36(5):528-30
del Campo M, Feitosa IML, Ribeiro EM, et al. The phenotypic spectrum of congenital Zika syndrome. Am J Med Genet 2017 Apr;173(4):841-57
de Lima Petribu NC, de Fatima Vasco Aragao M, van der Linden V, et al. Follow-up brain imaging of 37 children with congenital Zika syndrome: case series study. BMJ 2017 (published online Oct 13)
de Olveira WK, de Franca GVA, Carmo EH, et al. Infection-related microcephaly after the 2015 and 2016 Zika virus outbreaks in Brazil: a surveillance-based analysis. Lancet 2017 (published online Jun 21)
DeSilva M, Munoz FM, Sell E, et al. Congenital microcephaly: case definition & guidelines for data collection, analysis, and presentation of safety data after maternal immunisation. (Commentary) Vaccine 2017 (published online Nov 14)
Eggo RM, Kucharski AJ. Expected duration of adverse pregnancy outcomes after Zika epidemic. Emerg Infect Dis 2017 (published online Oct 23)
Fernandez MP, Saad EP,  Martinez MO, et al. Ocular histopathologic features of congenital Zika syndrome. JAMA Ophthalmol 2017 (published online Sep 21)
Graham KA, Fox DJ, Talati A, et al. Prevalence and clinical attributes of congenital microcephaly — New York, 2013-2015. MMWR 2017 Feb 10;66(5):125-9
Halai UA, Nielsen-Saines K, Moreira ME, et al. Maternal Zika virus disease severity, virus load, prior dengue antibodies and their relationship to birth outcomes. Clin Infect Dis 2017 (published online May 23)
Hall NB, Broussard K, Evert N, et al. Zika virus-associated neonatal birth defects surveillance — Texas, January 2016-July 2017. (Notes from the field) MMWR 2017 Aug 11;66(31):835-6
Hoyt AT, Canfield MA, Langlois PH, et al. Pre-Zika descriptive epidemiology of microcephaly in Texas, 2008–2012. Birth Defects Res 2017 (published online Nov 24)
Hurtado-Villa P, Puerto AK, Victoria S, et al. Raised frequency of central nervous system malformations related to Zika virus infection in two birth defects surveillance systems in Bogota and Cali, Colombia. Pediatr Infect Dis J 2017 (published online Jul 1)
Kapogiannis BG, Chakhtoura N, Hazra R, et al. Bridging knowledge gaps to understand how Zika virus exposure and infection affect child development. JAMA Pediatr 2017 (published online Feb 20)
Krauer F, Riesen M, Reveiz L, et al. Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barre syndrome: systematic review. PLoS Med 2017 Jan 3;14(1):e1002203
Lum FM, Low DKS, Fan Y, et al. Zika virus infects human fetal brain microglia and induces inflammation. Clin Infect Dis 2017 (published online Feb 21)
Mattar S, Ojeda C, Arboleda J, et al. Case report: microcephaly associated with Zika virus infection, Colombia. BMC Infect Dis 2017 (published online Jun 13)
McGrath EL, Rossi SL, Gao J, et al. Differential responses of human fetal brain neural stem cell to Zika virus infection. Stem Cell Rep 2017 (published online Feb 16)
Mejdoubi M, Monthieux A, Cassan T, et al. Brain MRI in infants after maternal Zika virus infection during pregnancy. (Letter) N Engl J Med 2017 (published online Oct 4)
Merfeld E, Ben-Avi L, Kennon M, et al. Potential mechanisms of Zika-linked microcephaly. Dev Biol 2017 (published online Apr 6)
Mohr EL, Block LN, Newman CM, et al. Ocular and uteroplacental pathology in macaque congenital Zika virus infection. bioRxiv 2017 Sep 30
Moreira-Soto A, Sarno M, Pedroso C, et al. Evidence for congenital Zika virus infection from neutralizing antibody titers in maternal sera, north-eastern Brazil. J Infect Dis 2017 (published online Oct 9)
Nogueira ML, Junior NRRN, Estofolete CF, et al. Adverse birth outcomes associated with Zika virus exposure during pregnancy in Sao Jose do Rio Preto, Brazil. Clin Microbiol Infect 2017 (published online Nov 10)
Orioli IM, Dolk H, Lopez-Camelo JS, et al. Prevalence and clinical profile of microcephaly in South America pre-Zika, 2005-14: prevalence and case-control study. BMJ 2017 Nov 21;359:j5018
Rasmussen SA, Meaney-Delman DM, Petersen LR, et al. Studying the effects of emerging infections on the fetus: experience with West Nile and Zika viruses. Birth Defects Res 2017 Mar 15;109(5):363-71
Reagan-Steiner S, Simeone R, Simon E, et al. Evaluation of placental and fetal tissue specimens for Zika virus infection — 50 states and District of Columbia, January-December, 2016. MMWR 2017 Jun 23;66(24):636-43
Reynolds MR, Jones AM, Petersen EE, et al. Update on Zika virus-associated birth defects and evaluation of all U.S. infants with congenital Zika virus exposure — U.S. Zika Pregnancy Registry, 2016. (Vital signs) MMWR 2017 Apr 4;66(Early release)
Santos VS, Oliveira SJG, Gurgel RQ, et al. Microcephaly in twins due to the Zika virus. Am J Trop Med Hyg 2017 (published online Apr 10)
Schaub B, Vouga M, Najioullah F, et al. Analysis of blood from Zika virus-infected fetuses: a prospective case series. Lancet Infect Dis 2017 (published online Feb 10)
Shapiro-Mendoza CK, Rice ME, Galang RR, et al. Pregnancy outcomes after maternal Zika virus infection during pregnancy — U.S. territories, January 1, 2016-April 25, 2017. MMWR 2017 Jun 8;66(Early release)
Sheridan MA, Yunusov D, Balaraman V, et al.
Vulnerability of primitive human placental trophoblast to Zika virus. Proc Natl Acad Sci USA 2017 (published online Feb 13)
Sousa AQ, Cavalcante DIM, Franco LM, et al. Postmortem findings for 7 neonates with congenital Zika virus infection. Emerg Infect Dis 2017 (published online May 1)
Tabata T, Petitt M, Puerta-Guardo H, et al. Zika virus replicates in proliferating cells in explants from first-trimester human placentas, potential sites for dissemination of infection. J Infect Dis 2017 (published online Nov 2)
Turner LH, Kinder JM, Adrienne Wilburn A, et al. Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection. PLoS Pathog 2017 Nov 16;13(11):e1006684
Vermillion MS, Lei J, Shabi Y, et al. Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes. Nat Commun 2017 (published online Feb 21)
Wang D, Chen C, Liu S, et al. A mutation identified in neonatal microcephaly destabilizes Zika virus NS1 assembly in vitro. Sci Rep 2017 (published online Feb 15)
Weaver SC. Emergence of epidemic Zika virus transmission and congenital Zika syndrome: are recently evolved traits to blame? mBio 2017 Jan 10;8(1):e02063-16
Yuan L, Huang XY, Liu ZY, et al. A single mutation in the prM protein of Zika virus contributes to fetal microcephaly. Science 2017 (published online Sep 28)
Zacharias N, Whitty J, Noblin S, et al. First neonatal demise with travel-associated Zika virus infection in the United States of America. AJP Rep 2017 Apr;7(2):e68-73
Zin AA, Tsui I, Rossetto J, et al. Screening criteria for ophthalmic manifestations of congenital Zika virus infection. JAMA Pediatr 2017 (published online Jul 17)

Cutaneous Symptoms

Chen L, Hafeez F, Curry CL, et al. Cutaneous eruption in a U.S woman with locally acquired Zika virus infection. (Letter) N Engl J Med 2017 (published online Jan 11)

Diagnostics

Balmaseda A, Stettler K, Medialdea-Carrera R, et al. Antibody-based assay discriminates Zika virus infection from other flaviviruses. PNAS 2017 (published online Jul 17)
Bosch I, de Puig H, Hiley M, et al.
Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum. Sci Transl Med 2017 (published online Sep 27)
Calvert AE, Biggerstaff BJ, Tanner NA, et al.
Rapid colorimetric detection of Zika virus from serum and urine specimens by reverse transcription loop-mediated isothermal amplification (RT-LAMP). PLoS One 2017 Sep 25;12(9):e0185340
Chibueze EC, Parsons AJQ, da Silva Lopes K, et al.
Diagnostic accuracy of ultrasound scanning for prenatal microcephaly in the context of Zika virus infection: a systematic review and meta-analysis. Sci Rep 2017 (published online May 23)
Chua A, Prat I, Nuebling CM, et al.
Update on Zika diagnostic tests and WHO’s related activities. PLoS Negl Trop Dis 2017 Feb 2;11(2):e0005269
Eppes C, Rac M, Dunn J, et al. Testing for Zika virus (ZIKV) infection in pregnancy: key concepts to deal with an emerging epidemic. Am J Obstet Gynecol 2017 (published online Jan 23)
Felix AC, Souza NCS, Figueiredo WM, et al. Cross reactivity of commercial anti-dengue immunoassays in patients with acute Zika virus infection. J Med Virol 2017 (published online Mar 3)
Goldfarb IT, Jaffe E, Lyerly AD. Responsible care in the face of shifting recommendations and imperfect diagnostics for Zika virus. JAMA 2017 (published online Oct 27)
Hancock WT, Soeters HM, Hills SL, et al. Establishing a timeline to discontinue routine testing of asymptomatic pregnant women for Zika virus infection — American Samoa, 2016-2017. MMWR 2017 Mar 24;66(11):299-301
Ho HJ, Wong JGX, Kyaw WM, et al.
Diagnostic accuracy of parameters for Zika and dengue virus infections, Singapore. Emerg Infect Dis 2017 (published online Nov 2)
Jiang Q, Chandar YJ, Cao S, et al.
Rapid, point-of-care, paper-based plasmonic biosensor for Zika virus diagnosis. Adv Biosyst 2017 (published online Aug 10)
Lee AJ, Bhattacharya R, Scheuermann RH, et al.
 Identification of diagnostic peptide regions that distinguish Zika virus from related mosquito-borne Flaviviruses. PLoS One 2017 May 31;12(5):e0178199.
L'Huillier AG, Hamid-Allie A, Kristjanson E, et al. Evaluation of Euroimmun anti-Zika virus ELISAs (IgM & IgG) for Zika virus serologic testing. J Clin Microbiol 2017 (published online May 31)
Lum FM, Lin C, Susova OY, et al. Sensitive detection of Zika virus antigen in patients' whole blood as an alternative diagnostic approach. J Infect Dis 2017 (published online Jun 6)
Oduyebo T, Polen KD, Walke HT, et al. Interim guidance for health care providers caring for pregnant women with possible Zika virus exposure — United States (including U.S. territories), July 2017. (Update) MMWR 2017 Jul 24;66(Early online)
Olschlager S, Enfissi A, Zaruba M, et al. Diagnostic validation of the RealStar Zika virus reverse transcription polymerase chain reaction kit for detection of Zika virus RNA in urine and serum specimens. Am J Trop Med Hyg 2017 Oct;97(4):1070-1
Priye A, Bird SW, Light YK, et al. A smartphone-based diagnostic platform for rapid detection of Zika, chikungunya, and dengue viruses. Sci Rep 2017 (published online Mar 20)
Safronetz D, Sloan A, Stein DR, et al. Evaluation of 5 commercially available Zika virus immunoassays. Emerg Infect Dis 2017 (published online Aug 17)
Tsai WY, Youn HH, Brites C, et al. Distinguishing secondary dengue virus infection from Zika virus infection with previous dengue by a combination of three simple serological tests. Clin Infect Dis 2017 (published online Jul 29)
Wahed AAE, Sanabani SS, Faye O, et al. Rapid molecular detection of Zika virus in acute-phase urine samples using the recombinase polymerase amplification assay. PLoS Curr 2017 Jan 25
Wilson HL, Tran T, Druce J, et al. A neutralization assay for Zika and Dengue viruses using a real-time PCR-based endpoint assessment. J Clin Microbiol 2017 (published online Aug 9)
Zhang B, Pinsky BA, Ananta JS, et al. Diagnosis of Zika virus infection on a nanotechnology platform. Nat Med 2017 (published online Mar 6)
Zuanazzi D, Arts EJ, Jorge PK, et al. Postnatal identification of Zika virus peptides from saliva. J Dent Res 2017 (published online Aug 21)

Economic Burden

Lee BY, Alfaro-Murillo JA, Parpia AS, et al. The potential economic burden of Zika in the continental United States. PLoS Negl Trop Dis 2017 Apr 27;11(4):e0005531

Epidemiology

Ali S, Gugliemini O, Harber S, et al. Environmental and social change drive the explosive emergence of Zika virus in the Americas. PLoS Negl Trop Dis 2017 Feb 9;11(2):e0005135
Boggild AK, Geduld J, Libman M, et al. Surveillance report of Zika virus among Canadian travelers returning from the Americas. CMAJ 2017 Mar 6;189(9):E334-40
Faria NR, Quick J, Morales I, et al. Epidemic establishment and cryptic transmission of Zika virus in Brazil and the Americas. bioRxiv 2017 Mar 27
Ferreira MLB, de Brito CAA, Moreira AJP, et al.
Guillain-Barre Syndrome, acute disseminated encephalomyelitis and encephalitis associated with Zika virus infection in Brazil: detection of viral RNA and isolation of virus during late infection. Am J Trop Med Hyg 2017 (published online Aug 28)
Griffin I, Zhang G, Fernandez D, et al.
Epidemiology of pediatric Zika virus infections. Pediatrics 2017 (published online Nov 1)
Grubaugh ND, Ladner JT, Kraemer MUG, et al.
Genomic epidemiology reveals multiple introductions of Zika virus into the United States. (Letter) Nature 2017 (published online May 24)
Herrera BB, Chang CA, Hamel DJ, et al. Continued transmission of Zika virus in humans in West Africa, 1992-2016. J Infect Dis 2017 (published online Apr 8)
Ho ZJM, Hapuarachchl HC, Barkham T, et al. Outbreak of Zika virus infection in Singapore: an epidemiological, entomological, virological, and clinical analysis. Lancet Infect Dis 2017 (published online May 17)
Lourenco J, de Lourdes Monteiro M, Valdez T, et al. Zika virus outbreak in Cabo Verde Islands, West Africa: early epidemiological findings. bioRxiv 2017 Oct 6
Massad E, Burattini MN, Khan K, et al. On the origin and timing of Zika virus introduction in Brazil. Epidemiol Infect 2017 (published online Jun 15)
Osorio-de-Castro CGS, Miranda ES, Machado de Freitas C, et al. The Zika virus outbreak in Brazil: knowledge gaps and challenges for risk reduction. Am J Public Health 2017 (published online Apr 20)
Reagan-Steiner S, Simeone R, Simon E, et al. Evaluation of placental and fetal tissue specimens for Zika virus infection — 50 states and District of Columbia, January-December, 2016. MMWR 2017 Jun 23;66(24):636-43
Rodriguez-Morales AJ, Ruiz P, Tabares J, et al. Mapping the ecoepidemiology of Zika virus infection in urban and rural areas of Pereira, Risaralda, Colombia, 2015-2016: implications for public health and travel medicine. Travel Med Infect Dis 2017 (published online May 6)
Sapkal GN, Yadav PD, Vegad MM, et al. First laboratory confirmation on the existence of Zika virus disease in India. J Infect 2017 (published online Oct 6)
Spiteri G, Sudre B, Septfons A. Surveillance of Zika virus infection in the EU/EEA, June 2015 to January 2017. Euro Surveill 2017 Oct 12;22(41):pii=17-00254
Wong N, Ahmed A, Ahmed O, et al. A series of Zika virus cases imported into the UK 2016: comparative epidemiological and clinical features. J Infect 2017 (published online Mar 23)
Zhang Q, Sun K, Chinazzi M, et al. Spread of Zika virus in the Americas. Proc Natl Acad Sci USA 2017 (published online Apr 25)

Genetic Characteristics

Black A, Potter B, Dudas G, et al. Genetic characterization of the Zika virus epidemic in the US Virgin Islands. bioRxiv 2017 Mar 3
Blohm GM, Lednicky JA, Marquez M, et al. Complete genome sequences of identical Zika virus isolates in a nursing mother and her infant. Genome Announc 2017 (published online Apr 27)
Faria NR, Quick J, Claro IM, et al.
Establishment and cryptic transmission of Zika virus in Brazil and the Americas. (Letter) Nature 2017 (published online May 24)
Garcez PP, Nascimento JM, de Vasconcelos JM, et al. Zika virus disrupts molecular fingerprinting of human neurospheres. Sci Rep 2017 (published online Jan 23)
Garg H, Sedano M, Plata G, et al. Development of virus like particle vaccine and reporter assay for Zika virus. J Virol 2017 (published online Aug 9)
Grubaugh ND, Ladner JT, Kraemer MUG, et al. Genomic epidemiology reveals multiple introductions of Zika virus into the United States. (Letter) Nature 2017 (published online May 24)
Gu SH, Song DH, Lee D, et al. Whole-genome sequence analysis of Zika virus, amplified from urine of traveler from the Philippines.Virus Genes 2017 (published online Aug 9)
Li G, Poulsen M, Fenyvuesvolgyi C, et al. Characterization of cytopathic factors through genome-wide analysis of the Zika viral proteins in fission yeast. Proc Natl Acad Sci USA 2017 (published online Jan 3)
Metsky HC, Matranga CB, Wohl S, et al. Zika virus evolution and spread in the Americas. (Letter) Nature 2017 (published online May 24)
Moni MA, Lio P. Genetic profiling and comorbidities of Zika infection. J Infect Dis 2017 (published online Jul 27)
Setoh YX, Prow NA, Peng N, et al. De novo generation and characterization of new Zika virus isolate using sequence data from a microcephaly case. mSphere 2017 (published online May 17)
Widman DG, Young E, Yount BL, et al. A reverse genetics platform that spans the Zika virus family tree. mBio 2017 Mar 7;8(2):e02014-16
Yudhaputri FA, Trimarsanto H, Perkasa A, et al. Genomic characterization of Zika virus isolated from Indonesia. Virology 2017 (published online Jul 26)

Literature Review

Albuquerque PC, Castro MJC, Santos-Gandelman J, et al. Bibliometric indicators of the Zika outbreak. PLoS Negl Trop Dis 2017 Jan 19;11(1): e0005132

Male Fertility Issues

de Laval F, Matheus S, Labrousse T, et al. Kinetics of Zika viral load in semen. (Letter to the editor) N Engl J Med 2017 (published online Aug 17)
Joguet G, Mansuy JM, Matusali G, et al.
Effect of acute Zika virus infection on sperm and virus clearance in body fluids: a prospective observational study. Lancet Infect Dis 2017 (published online Aug 21)
Shan C, Muruato AE, Jagger BW, et al.
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage. Nat Commun 2017 (published online Sep 22)
Uraki R, Hwang J, Jurado KA, et al.
Zika virus causes testicular atrophy. Sci Adv 2017 Feb 22;3(2):e1602899

Musculoskeletal Sequelae

Molko N, Simon O, Guyon D, et al. Zika virus infection and myasthenia gravis: report of 2 cases. Neurology 2017 (published online Feb 10)

Neurologic Manifestations

Aid M, Abbink P, Larocca RA, et al. Zika virus persistence in the central nervous system and lymph nodes of rhesus monkeys. Cell 2017 (published online Apr 27)
Anaya JM, Rodriguez Y, Monsalve DM, et al. A comprehensive analysis and immunobiology of autoimmune neurological syndromes during the Zika virus outbreak in Cucuta, Colombia. J Autoimmun 2017 (published online Jan 3)
Brito CAA, Azevedo F, Cordeiro MT, et al. Central and peripheral nervous system involvement caused by Zika and chikungunya coinfection. PLoS Negl Trop Dis 2017 Jul 13;11(7):e0005583
Chavali PL, Stojic L, Meredith LW, et al. Neurodevelopmental protein Musashi 1 interacts with the Zika genome and promotes viral replication. Science 2017 (published online Jun 1)
Costa VV, Del Sarto JL, Rocha RF, et al. N-methyl-d-aspartate (NMDA) receptor blockade prevents neuronal death induced by Zika virus infection. mBio 2017 Apr 25;8(2):e00350-17
Coelho AVC, Crovella S. Microcephaly prevalence in infants born to Zika virus-infected women: a systematic review and meta-analysis. Int J Mol Sci 2017 (published online Aug 5)
Cui L, Zou P, Chen E, et al. Visual and motor deficits in grown-up mice with congenital Zika virus infection. eBioMedicine 2017 (published online Apr 24)
da Silva IRF, Frontera JA, de Filippis AMB, et al. Neurologic complications associated with the Zika virus in Brazilian adults. JAMA Neurol 2017 (published online Aug 14)
de Lima Petribu NC, de Fatima Vasco Aragao M, van der Linden V, et al. Follow-up brain imaging of 37 children with congenital Zika syndrome: case series study. BMJ 2017 (published online Oct 13)
Dirlikov E, Medina NA, Major CG, et al. Acute Zika virus infection as a risk factor for Guillain-Barre syndrome in Puerto Rico. (Letter) JAMA 2017 Oct 17;318(15):1498-1500
Gabriel E, Ramani A, Karow U, et al. Recent Zika virus isolates induce premature differentiation of neural progenitors in human brain organoids. Cell Stem Cell 2017 (published online Jan 26)
Hurtado-Villa P, Puerto AK, Victoria S, et al. Raised frequency of central nervous system malformations related to Zika virus infection in two birth defects surveillance systems in Bogota and Cali, Colombia. Pediatr Infect Dis J 2017 (published online Jul 1)
Jurado KA, Yockey LJ, Wong PW, et al. Antiviral CD8 T cells induce Zika-virus-associated paralysis in mice. Nat Microbiol 2017 (published online Nov 20)
Kam YW, Leite JA, Lum FM, et al. Specific biomarkers associated with neurological complications and congenital CNS abnormalities from Zika virus-infected patients in Brazil. J Infect Dis 2017 (published online May 30)
Krauer F, Riesen M, Reveiz L, et al. Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barre syndrome: systematic review. PLoS Med 2017 Jan 3;14(1):e1002203
Landais A, Audrey Cesaire A, Fernandez M, et al. Zika vasculitis: a new cause of stroke in children? (Letter) J Neurol Sci 2017 (published online Oct 27)
Mejdoubi M, Monthieux A, Cassan T, et al. Brain MRI in infants after maternal Zika virus infection during pregnancy. (Letter) N Engl J Med 2017 (published online Oct 4)
Oh Y, Zhang F, Wang Y, et al. Zika virus directly infects peripheral neurons and induces cell death. Nat Neurosci 2017 (published online Jul 31)
Ramalho FS, Yamamoto AY, da Silva LL, et al. Congenital Zika virus infection induces severe spinal cord injury. Clin Infect Dis 2017 (published online Apr 21)
Rosenfeld AB, Doobin DJ, Warren AL, et al. Replication of early and recent Zika virus isolates throughout mouse brain development. Proc Natl Acad Sci USA 2017 (published online Oct 31)
Roze B, Najioullah F, Ferge JL, et al. Guillain-Barre syndrome associated with Zika virus infection in Martinique in 2016: a prospective study. Clin Infect Dis 2017 (published online Jul 20)
Salinas JL, Major CG, Pastula DM, et al. Incidence and clinical characteristics of Guillain-Barre syndrome before the introduction of Zika virus in Puerto Rico. J Neurol Sci 2017 (published online Apr 7)
Salinas JL, Walteros DM, Styczynski A, et al. Zika virus disease-associated Guillain-Barre syndrome — Barranquilla, Colombia 2015-2016. J Neurol Sci 2017 (published online Sep 4)
Schwartzmann PV, Ramalho LNZ, Neder L, et al. Zika virus meningoencephalitis in an immunocompromised patient. Mayo Clin Proc 2017 Mar;92(3):460-6
Styczynski AR, Malta JMAS, Krow-Lucal ER, et al. Increased rates of Guillain-Barre syndrome associated with Zika virus outbreak in the Salvador metropolitan area, Brazil. PLoS Negl Trop Dis 2017 Aug 30;11(8):e0005869
Tsakiri S, Zacharias N, Garcia J, et al. Cranial asymmetry versus microcephaly: implications for practice during the Zika virus epidemic. Tex Med 2017 Aug 2;113(9):e1
van den Pol AN, Mao G, Yang Y, et al. Zika virus targeting in the developing brain. J Neurosci 2017 (published online Jan 25)
Yi L, Pimentel H, Pachter L. Zika infection of neural progenitor cells perturbs transcription in neurodevelopmental pathways. PLoS One 2017 Apr 27;12(4):e0175744
Yuan L, Huang XY, Liu ZY, et al. A single mutation in the prM protein of Zika virus contributes to fetal microcephaly. Science 2017 (published online Sep 28)

Non-Human Primate Infections

Aid M, Abbink P, Larocca RA, et al. Zika virus persistence in the central nervous system and lymph nodes of rhesus monkeys. Cell 2017 (published online Apr 27)
Best K, Guedj J, Madelain V, et al. Zika plasma viral dynamics in nonhuman primates provides insights into early infection and antiviral strategies. Proc Natl Acad Sci USA 2017 (published online Aug 1)
Carroll T, Lo M, Lanteri M, et al. Zika virus preferentially replicates in the female reproductive tract after vaginal inoculation of rhesus macaques.PLoS Pathog 2017 Jul 26;13(7):e1006537
Chiu CY, Bouquet J, Li T, et al. Experimental Zika virus infection in a new world monkey model reproduces key features of the human disease. bioRxiv  2017 Jan 21
George J, Valiant WG, Mattapallil MJ, et al. Prior exposure to Zika virus significantly enhances peak dengue-2 viremia in rhesus macaques. Sci Rep 2017 (published online Sep 5)
Haddow AD, Nalca A, Rossi FD, et al. High infection rates for adult macaques after intravaginal or intrarectal inoculation with Zika virus. Emerg Infect Dis 2017 (published online May 26)
Hirsch AJ, Smith JL, Haese NN, et al. Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues. PLoS Pathog 2017 Mar 9;13(3):e1006219
Magnani DM, Rogers TF, Beutler N, et al. Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques. Sci Transl Med 2017 (published online Oct 4)
McCracken MK, Gromowski GD, Friberg HL, et al. Impact of prior flavivirus immunity on Zika virus infection in rhesus macaques. PLoS Pathog 2017 Aug 3;13(8):e1006487
Newman C, Friedrich TC, O’Connor DH. Macaque monkeys in Zika virus research: 1947-present. Curr Opin Virol 2017 (published online Jul 24)
Newman CM, Dudley DM, Aliota MT, et al. Oropharyngeal mucosal transmission of Zika virus in rhesus macaques. Nat Commun 2017 (published online Aug 1)
Nguyen SM, Antony KM, Dudley DM, et al. Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques. bioRxiv 2017 May 11
Pantoja P, Perez-Guzman EX, Rodriguez IV, et al. Zika virus pathogenesis in rhesus macaques is unaffected by pre-existing immunity to dengue virus. Nat Commun 2017 (published online Jun 23)
Vanchiere JA, Ruiz JC, Brady AG, et al. Experimental Zika virus infection of neotropical primates. Am J Trop Med Hyg 2017 (published online Nov 27)

Non-Mosquito Vectors

Darbellay J, Lai K, Babiuk S, et al. Neonatal pigs are susceptible to experimental Zika virus infection. (Letter) Emerg Microb Infect 2017 (published online Feb 15)
Ragan IK, Blizzard EL, Gordy P, et al. Investigating the potential role of North American animals as hosts for Zika virus. Vector Borne Zoonotic Dis 2017 (published online Feb 1)

Ophthalmologic Manifestations

Aleman TS, Ventura CV, Cavalcanti MM, et al. Quantitative assessment of microstructural changes of the retina in infants with congenital Zika syndrome. JAMA Opthalmol 2017 (published online Sep 7)
Fernandez MP, Saad EP,  Martinez MO, et al.
Ocular histopathologic features of congenital Zika syndrome. JAMA Ophthalmol 2017 (published online Sep 21)
Mohr EL, Block LN, Newman CM, et al. Ocular and uteroplacental pathology in macaque congenital Zika virus infection. bioRxiv 2017 Sep 30
Tan JJL, Balne PK, Leo YS, et al.
Persistence of Zika virus in conjunctival fluid of convalescence patients. Sci Rep 2017 (published online Sep 11)
Yepez JB, Murati FA, Pettito M, et al.
Ophthalmic manifestations of congenital Zika syndrome in Colombia and Venezuela. JAMA Ophthamol 2017 (published online Apr 13)
Zin AA, Tsui I, Rossetto J, et al. Screening criteria for ophthalmic manifestations of congenital Zika virus infection. JAMA Pediatr 2017 (published online Jul 17)

Outbreak Dynamics, Control

Alaniz AJ, Bacigalupo A, Cattan PE. Spatial quantification of the world population potentially exposed to Zika virus. Int J Epidemiol 2017 (published online Feb 23)
Andronico A, Dorleans F, Ferge JL, et al. Real-time assessment of health-care requirements during the Zika virus epidemic in Martinique. Am J Epidemiol 2017 (published online Feb 15)
Brooks T, Roy-Burman A, Tuholske C, et al. Real-time evolution of Zika virus disease outbreak, Roatan, Honduras. Emerg Infect Dis 2017 (published online Apr 27)
Castro LA, Fox SJ, Chen X, et al. Assessing real-time Zika risk in the United States. bioRxiv 2017 Mar 22
Castro M, Perez D, Guzman MG, et al.
Why did Zika not explode in Cuba? The role of active community participation to sustain control of vector-borne diseases. Am J Trop Med Hyg 2017 Aug;97(2):311-2
Faria NR, Quick J, Claro IM, et al.
Establishment and cryptic transmission of Zika virus in Brazil and the Americas.(Letter) Nature 2017 (published online May 24)
GAO (US Government Accountability Office). Emerging infectious diseases: actions needed to address the challenges of responding to Zika virus disease outbreaks. GAO-17-445. May 23, 2017
He D, Gao D, Lou Y, et al. A comparison study of Zika virus outbreaks in French Polynesia, Colombia and the state of Bahia in Brazil. Sci Rep 2017 (published online Mar 21)
Ho ZJM, Hapuarachchl HC, Barkham T, et al. Outbreak of Zika virus infection in Singapore: an epidemiological, entomological, virological, and clinical analysis. Lancet Infect Dis 2017 (published online May 17)
Kroelinger CD, Romero L, Lathrop E, et al. State and local implementation strategies for increasing access to contraception during zika preparedness and response — United States, September 2016. (Meeting summary) MMWR 2017 Nov 10;66(44):1230-5
Lourenco J, de Lourdes Monteiro M, Valdez T, et al. Zika virus outbreak in Cabo Verde Islands, West Africa: early epidemiological findings. bioRxiv 2017 Oct 6
Marini G, Guzzetta G, Rosa R, et al. First outbreak of Zika virus in the continental United States: a modelling analysis. Euro Surveill 2017 Sep 14;22(37):pii=30612
Massad E, Burattini MN, Khan K, et al. On the origin and timing of Zika virus introduction in Brazil. Epidemiol Infect 2017 (published online Jun 15)
Metsky HC, Matranga CB, Wohl S, et al. Zika virus evolution and spread in the Americas. (Letter) Nature 2017 (published online May 24)
Mordecai EA, Cohen JM, Evans MV, et al. Detecting the impact of temperature on transmission of Zika, dengue, and chikungunya using mechanistic models. PLoS Negl Trop Dis 2017 Apr 27;11(4):e0005568
Musso D, Bossin H, Mallet HP, et al. Zika virus in French Polynesia 2013-14: anatomy of a completed outbreak. Lancet Infect Dis 2017 (published online Nov 14)
Osorio-de-Castro CGS, Miranda ES, Machado de Freitas C, et al. The Zika virus outbreak in Brazil: knowledge gaps and challenges for risk reduction. Am J Public Health 2017 (published online Apr 20)
Pompon J, Morales-Vargas R, Manuel M, et al. A Zika virus from America is more efficiently transmitted than an Asian virus by Aedes aegypti mosquitoes from Asia. Sci Rep 2017 (published online Apr 27)
Ryan SJ, Carlson CJ, Stewart-Ibarra AM, et al. Outbreak of Zika virus infections, Dominica, 2016. Emerg Infect Dis 2017 (published online Oct 11)
Shacham E, Nelson EJ, Hoft DF, et al. Potential high-risk areas for
Zika virus transmission in the contiguous United States
. Am J Public Health 2017 (published online Mar 21)
Teng Y, Bi D, Xie G, et al. Dynamic forecasting of Zika epidemics using Google Trends. PLoS One 2017 Jan 6;12(1):e0165085
Zhang Q, Sun K, Chinazzi M, et al. Spread of Zika virus in the Americas. Proc Natl Acad Sci USA 2017 (published online Apr 25)

Pregnancy

Adhikari EH, Nelson DB, Johnson KA, et al.Infant outcomes among women with ZIka virus infection during pregnancy: results of a large prenatal Zika screening program. Am J Obstet Gynecol 2017 (published online Jan 30)
Blohm GM, Lednicky JA, Marquez M, et al. Complete genome sequences of identical Zika virus isolates in a nursing mother and her infant. Genome Announc 2017 (published online Apr 27)
Berenson AB, Hirth JM, Guo F, et al. Prevention practices among the United States pregnant women who travel to Zika outbreak areas.Am J Trop Med Hyg 2017 (published online Oct 23)
D'Angelo DV, von Essen BS, Lamias MJ, et al.
Measures taken to prevent Zika virus infection during pregnancy — Puerto Rico, 2016. MMWR 2017 Jun 9;66(22):574-8
Eppes C, Rac M, Dunn J, et al. Testing for Zika virus (ZIKV) infection in pregnancy: key concepts to deal with an emerging epidemic. Am J Obstet Gynecol 2017 (published online Jan 23)
Flamand C, Fritzell C, Matheus S, et al. The proportion of asymptomatic infections and spectrum of disease among pregnant women infected by Zika virus: systematic monitoring in French Guiana, 2016. Euro Surveill 2017 Nov 2;22(44):pii=17-00102
Hancock WT, Soeters HM, Hills SL, et al. Establishing a timeline to discontinue routine testing of asymptomatic pregnant women for Zika virus infection — American Samoa, 2016-2017. MMWR 2017 Mar 24;66(11):299-301
Mejdoubi M, Monthieux A, Cassan T, et al. Brain MRI in infants after maternal Zika virus infection during pregnancy. (Letter) N Engl J Med 2017 (published online Oct 4)
Nguyen SM, Antony KM, Dudley DM, et al. Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques. PLoS Pathog 2017 May 25;13(5):e1006378
Oduyebo T, Polen KD, Walke HT, et al. Interim guidance for health care providers caring for pregnant women with possible Zika virus exposure — United States (including U.S. territories), July 2017. (Update) MMWR 2017 Jul 24;66(Early online)
Prue CE, Roth Jr. JN, Garcia-Williams A, et al. Awareness, beliefs, and actions concerning Zika virus among pregnant women and community members — U.S. Virgin Islands, November-December 2016. MMWR 2017 Aug 31;66(34):909-13
Rao R, Gaw SL, Han CS, et al. Zika risk and pregnancy in the clinical practice: ongoing experience as the outbreak evolves. Obstet Gynecol 2017 (published online May 5)
Shapiro-Mendoza CK, Rice ME, Galang RR, et al. Pregnancy outcomes after maternal Zika virus infection during pregnancy — U.S. territories, January 1, 2016-April 25, 2017. MMWR 2017 Jun 8;66(Early release)
Shan C, Muruato AE, Jagger BW, et al. A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage. Nat Commun 2017 (published online Sep 22)
Terzian ACB, Estofolete CF, da Silva RA, et al. Long-term viruria in Zika virus-infected pregnant women, Brazil, 2016. Emerg Infect Dis 2017 (published online Oct 2)
Winkler CW, Woods TA, Rosenke R, et al. Sexual and vertical transmission of Zika virus in anti-interferon receptor-treated Rag1-deficient mice. Sci Rep 2017 (published online Aug 3)

Risk

Ajelli M, Moise IK, Hutchings TCSG, et al. Host outdoor exposure variability affects the transmission and spread of Zika virus: insights for epidemic control. PLoS Negl Trop Dis 2017 Sep 14;11(9):e0005851
Alaniz AJ, Bacigalupo A, Cattan PE.
Spatial quantification of the world population potentially exposed to Zika virus. Int J Epidemiol 2017 (published online Feb 23)
Asher J, Barker C, Chen G, et al.
Preliminary results of models to predict areas in the Americas with increased likelihood of Zika virus transmission in 2017. bioRxiv 2017 Sep 29
Castro LA, Fox SJ, Chen X, et al. Assessing real-time Zika risk in the United States. BMC Infect Dis 2017 May 4;17:284
Coimbra BM, Coelho FC, Armstrong M, et al. Zika: an ongoing threat to women and infants. bioRxiv 2017 Nov 16
Colon-Gonzalez FJ, Peres CA, Bernardo CSS, et al. After the epidemic: Zika virus projections for Latin America and the Caribbean. PLoS Negl Trop Dis 2017 Nov 1;11(11):e0006007
Duchemin JB, Mee PT, Lynch SE, et al. Zika vector transmission risk in temperate Australia: a vector competence study. Virol J 2017 (published online Jun 9)
Fuller TL, Calvet G, Estevam CG, et al.
Behavioral, climatic, and environmental risk factors for Zika and Chikungunya virus infections in Rio de Janeiro, Brazil, 2015-16. PLoS One 2017 Nov 16;12(11):e0188002
Gridley-Smith CL.
Examining mosquito surveillance and control capacity in the top 10 areas at risk for Zika virus exposure in the United States. J Public Health Manag Pract 2017 Aug;23(5):515-7
Lee CT, Greene SK,  Baumgartner J, et al.
Disparities in Zika virus testing and incidence among women of reproductive age — New York City, 2016. J Public Health Manag Pract 2017 (published online Oct 27)
Rodriguez-Valero N, Borobia AM, Lago M, et al.
Zika virus screening among Spanish team members after 2016 Rio de Janeiro, Brazil, Olympic Games. Emerg Infect Dis 2017 (published online Jun 19)
Siraj AS, Perkins TA. Assessing the population at risk of Zika virus in Asia — is the emergency really over? BMJ Glob Health 2017 (published online Sep 25)
Song S, Li Y, Fu S, et al. Could Zika virus emerge in mainland China? Virus isolation from nature in Culex quinquefasciatus, 2016. Emerg Microbes Infect 2017 (published online Nov 1)
van Meer R, Hohenadel K, Fitzgerald-Husek A, et al. Zika virus in Ontario: evaluating a rapid risk assessment tool for emerging infectious disease threats. Health Security 2017 (published online Jun 1)
Watts AG, Miniota J, Joseph HA, et al.
Elevation as a proxy for mosquito-borne Zika virus transmission in the Americas. PLoS One 2017 May 24;12(5):e0178211

Serology

Aubry M, Teissier A, Huart M, et al. Zika virus seroprevalence, French Polynesia, 2014-2015. Emerg Infect Dis 2017 (published online Jan 13)
Buechler CR, Bailey AL, Weiler AM, et al. Seroprevalence of Zika virus in wild African green monkeys and baboons. mSphere 2017 (published online Mar 8)
Gake B, Vernet MA, Leparc-Goffart I, et al. Low seroprevalence of Zika virus in Cameroonian blood donors. Braz J Infect Dis 2017 (published online May 23)
Gallian P, Cabie A, Richard P, et al. Zika virus in asymptomatic blood donors in Martinique. (Letter) Blood 2017 Jan 12;129(2):263-6
L'Huillier AG, Hamid-Allie A, Kristjanson E, et al. Evaluation of Euroimmun anti-Zika virus ELISAs (IgM & IgG) for Zika virus serologic testing. J Clin Microbiol 2017 (published online May 31)
Moreira-Soto A, Sarno M, Pedroso C, et al. Evidence for congenital Zika virus infection from neutralizing antibody titers in maternal sera, north-eastern Brazil. J Infect Dis 2017 (published online Oct 9)
Netto EM, Moreira-Sotoc A, Pedroso C, et al. High Zika virus seroprevalence in Salvador, northeastern Brazil limits the potential for further outbreaks. mBio 2017 (published online Nov 14)

Sexual & Other Non-Vector Transmission

Allard A, Althouse BM, Hebert-Dufresne L, et al. The risk of sustained sexual transmission of Zika is underestimated. PLoS Pathog 2017 Sep 21;13(9):e1006633
Blohm GM, Lednicky JA, Marquez M, et al.
Complete genome sequences of identical Zika virus isolates in a nursing mother and her infant. Genome Announc 2017 (published online Apr 27)
Carroll T, Lo M, Lanteri M, et al. Zika virus preferentially replicates in the female reproductive tract after vaginal inoculation of rhesus macaques.PLoS Pathog 2017 Jul 26;13(7):e1006537
Colt S, Garcia-Casal MN, Pena-Rosas JP, et al.
Transmission of Zika virus through
breast milk and other breastfeeding-related bodily-fluids: a systematic review
. PLoS Negl Trop Dis 2017 Apr 10;11(4):e0005528
de Laval F, Matheus S, Labrousse T, et al. Kinetics of Zika viral load in semen. (Letter to the editor) N Engl J Med 2017 (published online Aug 17)
Deng YQ, Zhang NN, Li XF, et al. Intranasal infection and contact transmission of Zika virus in guinea pigs. Nat Commun 2017 (Nov 21)
Duggal NK, Ritter JM, Pestorius SE, et al. Frequent Zika virus sexual transmission and prolonged viral RNA shedding in an immunodeficient mouse model. Cell Rep 2017 Feb 14;18(7):1751-60
Faria NR, Quick J, Morales I, et al. Epidemic establishment and cryptic transmission of Zika virus in Brazil and the Americas. BioRxiv 2017 Feb 2
Folkers KM, Caplan AL, Igel LH. Zika, sexual transmission and prudent public health policy. Public Health 2017 (published online Apr 15)
Kroelinger CD, Romero L, Lathrop E, et al. State and local implementation strategies for increasing access to contraception during zika preparedness and response — United States, September 2016. (Meeting summary) MMWR 2017 Nov 10;66(44):1230-5
Haddow AD, Nalca A, Rossi FD, et al. High infection rates for adult macaques after intravaginal or intrarectal inoculation with Zika virus. Emerg Infect Dis 2017 (published online May 26)
Hamer DH, Wilson ME, Jean J, et al. Epidemiology, prevention, and potential future treatments of sexually transmitted Zika virus infection. Curr Infect Dis Rep 2017 (published online Mar 9)
Heck E, Cavanagh HD, Robertson DM. Zika virus RNA in an asymptomatic donor's vitreous: risk for transmission? (Letter) Am J Transplant 2017 (published online Apr 27)
Joguet G, Mansuy JM, Matusali G, et al. Effect of acute Zika virus infection on sperm and virus clearance in body fluids: a prospective observational study. Lancet Infect Dis 2017 (published online Aug 21)
Krow-Lucal ER, Biggerstaff BJ, Staples JE. Estimated incubation period for Zika virus disease. Emerg Infect Dis 2017 (published online Mar 10)
Martinez LE, Garcia G, Contreras D, et al. Pathogenesis of Zika virus infection via rectal route. bioRxiv 2017 Apr 19
McDonald EM, Duggal NK, Brault AC. Pathogenesis and sexual transmission of Spondweni and Zika viruses. PLoS Negl Trop Dis 2017 Oct 6;11(10):e0005990.
Moreira J, Peixoto TM, Machado de Siqueira A, et al. Sexually acquired Zika virus: a systematic review. Clin Microbiol Infect 2017 (published online Jan 3)
Newman CM, Dudley DM, Aliota MT, et al. Oropharyngeal mucosal transmission of Zika virus in rhesus macaques. Nat Commun 2017 (published online Aug 1)
Paz-Bailey G, Rosenberg ES, Doyle K, et al. Persistence of Zika virus in body fluids — preliminary report. N Engl J Med 2017 (published online Feb 14)
Spencer JL, Lahon A, Tran LL, et al. Replication of Zika virus in human prostate cells: a potential source of sexually transmitted virus. J Infect Dis 2017 (published online Aug 24)
Sotelo JR, Sotelo AB, Sotelo FBJ, et al. Persistence of Zika virus in breast milk after infection in late stage of pregnancy. Emerg Infect Dis 2017 (published online Feb 13)
Tan JJL, Balne PK, Leo YS, et al. Persistence of Zika virus in conjunctival fluid of convalescence patients. Sci Rep 2017 (published online Sep 11)
Uraki R, Jurado KA, Hwang J, et al. Sexual transmission of ZIKV causes fetal growth restriction in mice. J Infect Dis 2017 (published online May 2)
Vouga M, Musso D, Schuab B, et al. Zika virus: are we going too far? (Letter) Lancet 2017 (published online Jan 14)
Winkler CW, Woods TA, Rosenke R, et al. Sexual and vertical transmission of Zika virus in anti-interferon receptor-treated Rag1-deficient mice. Sci Rep 2017 (published online Aug 3)

Societal Implications

Bragazzi NL, Alicino C, Trucchi C, et al. Global reaction to the recent outbreaks of Zika virus: insights from a Big Data analysis. PLoS One 2017 Sep 21;12(9):e0185263
Castro M, Perez D, Guzman MG, et al.
Why did Zika not explode in Cuba? The role of active community participation to sustain control of vector-borne diseases. Am J Trop Med Hyg 2017 Aug;97(2):311-2
Diaz-Quijano FA, Filho ADPC.
Reduction of the birth rate in Sao Paulo: a probable effect of the panic caused by the Zika-associated microcephaly epidemic. Ann Epidemiol 2017 (published online Aug 12)
Rodriguez-Diaz CE, Garriga-Lopez A, Malave-Rivera SM, et al.
Zika virus epidemic in Puerto Rico: health justice too long delayed. Int J Infect Dis 2017 (published online Nov 15)
Seltzer EK, Horst-Martz E, Lu M, et al.
Public sentiment and discourse about Zika virus on Instagram. Public Health 2017 (published online Aug 12)

Travelers

Boggild AK, Geduld J, Libman M, et al. Surveillance report of Zika virus among Canadian travelers returning from the Americas. CMAJ 2017 Mar 6;189(9):E334-40
Leder K, Grobusch MP, Gautret P, et al. Zika beyond the Americas: travelers as sentinels of Zika virus transmission. A GeoSentinel analysis, 2012 to 2016. PLoS One 2017 Oct 3;12(10):e0185689

Vaccines

Boigard H, Alimova A, Martin GR, et al. Zika virus-like particle (VLP) based vaccine. PLoS Negl Trop Dis 2017 May 8;11(5): e0005608
Brault AC, Domi A, McDonald EM, et al. A Zika vaccine targeting NS1 protein protects immunocompetent adult mice in a lethal challenge model. Sci Rep 2017 (published online Nov 7)
Fernandez E, Diamond MS. Vaccination strategies against Zika virus. Curr Opin Virol 2017 (published online Apr 19)
Garg H, Sedano M, Plata G, et al. Development of virus like particle vaccine and reporter assay for Zika virus. J Virol 2017 (published online Aug 9)
Griffin BD, Muthumani K, Warner BM, et al. DNA vaccination protects mice against Zika virus-induced damage to the testes. Nat Commun 2017 (published online Jun 7)
Lagunas-Rangel FA, Viveros-Sandoval ME, Reyes-Sandoval A. Current trends in Zika vaccine development. J Virus Erad 2017 (published online Jul 1)
McArthur MA. Zika virus: recent advances towards the development of vaccines and therapeutics. Viruses 2017 (published online Jun 13)
Pardi N, Hogan MJ, Pelc RS, et al. Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination. (Letter) Nature 2017 (published online Feb 2)
Richner JM, Himansu S, Dowd KA, et al. Modified mRNA vaccines protect against Zika virus infection. Cell 2017 (published online Feb 17)
Richner JM, Jagger BW, Shan C, et al. Vaccine mediated protection against Zika virus-induced congenital disease. Cell 2017 (published online Jul 13)
Shan C, Muruato AE, Nunes BTD, et al. A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models. Nat Med 2017 (published online Apr 10)
Shan C, Muruato AE, Jagger BW, et al. A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage. Nat Commun 2017 (published online Sep 22)
Tebas P, Roberts CC, Muthumani K, et al. Safety and immunogenicity of an anti-Zika virus DNA vaccine — preliminary report. N Engl J Med 2017 (published online Oct 4)
Thomas SJ. Zika virus vaccines — a full field and looking for the closers. N Engl J Med 2017 May 11;378(19):1883-6
Xie X, Yang Y, Muruato AE, et al. Understanding Zika virus stability and developing a chimeric vaccine through functional analysis. MBio 2017 Feb 7;8(1)e02134-16
Yang Y, Shan C, Zou J, et al. A cDNA clone-launched platform for high-yield production of inactivated Zika vaccine. EBioMedicine 2017 (published online Feb 6)

Vector Control/Mosquito Transmission

Abad-Franch F, Zamora-Perea E, Luz SLB. Mosquito-disseminated insecticide for citywide vector control and its potential to block arbovirus epidemics: entomological observations and modeling results from Amazonian Brazil. PLoS Med 2017 Jan 17;14(1):e1002213
Armstrong PM, Andreadis TG, Shepard JJ, et al. Northern range expansion of the Asian tiger mosquito (Aedes albopictus): analysis of mosquito data from Connecticut, USA. PLoS Negl Trop Dis 2017 May 18;11(5):e0005623
Ayllon T, de Mendonca Campos Renata, Brasil P, et al. Early evidence for Zika virus circulation among Aedes aegypti mosquitoes, Rio de Janeiro, Brazil. Emerg Infect Dis 2017 (published online Jun 19)
Azar SR, Roundy CM, Rossi SL, et al. Differential vector competency of Aedes albopictus populations from the Americas for Zika virus. Am J Trop Hyg 2017 (published online May 8)
Balestrino F, Puggioli A, Carrieri M, et al. Quality control methods for Aedes albopictus sterile male production. PLoS Negl Trop Dis 2017 Sep 11;11(9):e0005881
Bibbs CS, Kaufman PE. Volatile pyrethroids as a potential mosquito abatement tool: a review of pyrethroid-containing spatial repellents. J Integr Pest Manag 2017 (published online Aug 2)
Bradt DL, Bradley KK, Hoback WW, et al. New records of Aedes aegypti in southern Oklahoma, 2016. J Am Mosq Control Assoc 2017 Mar;33(1):56-9
Burkhalter KL, Savage HM. Detection of Zika virus in desiccated mosquitoes by real-time reverse transcription PCR and plaque assay. Emerg Infect Dis 2017 (published online Jan 11)
Carvalho MS, Honorio NA, Garcia LMT, et al. Aedes aegypti control in urban areas: a systemic approach to a complex dynamic. PLoS Negl Trop Dis 2017 Jul 27;11(7):e0005632
Cevallos V, Ponce P, Waggoner JJ, et al. Zika and Chikungunya virus detection in naturally infected Aedes aegypti in Ecuador. Acta Trop 2017 (published online Oct 2)
Ciota AT, Bialosuknia SM, Ehrbar DJ, et al. Vertical transmission of Zika virus by Aedes aegypti and Ae. albopictus mosquitoes. Emerg Infect Dis. 2017 (published online Mar 9)
de Oliveira S, Villela DAM, Dias FBS, et al. How does competition among wild type mosquitoes influences the performance of Aedes aegypti and dissemination of Wolbachia pipientis? PLoS Negl Trop Dis 2017 Oct 9;11(10):e0005947
Duchemin JB, Mee PT, Lynch SE, et al. Zika vector transmission risk in temperate Australia: a vector competence study. Virol J 2017 (published online Jun 9)
Elizondo-Quiroga D, Medina-Sanchez A, Sanchez-Gonzalez JM, et al. Zika virus in salivary glands of five different species of wild-caught mosquitoes from Mexico. bioRxiv 2017 Jun 19
Epelboin Y, Talaga S, Epelboin L, et al.
Zika virus: an updated review of competent or naturally infected mosquitoes. PLoS Negl Trop Dis 2017 Nov 16;11(11):e0005933
Etebari K, Hegde S, Saldana MA, et al.
Global transcriptome analysis of Aedes aegypti mosquitoes in response to Zika virus infection. bioxRiv 2017 Aug 22
Francis S, Saavedra-Rodriguez K, Perera R, et al.
Insecticide resistance to permethrin and malathion and associated mechanisms in Aedes aegypti mosquitoes from St. Andrew Jamaica. PLoS One 2017 Jun 26;12(6):e0179673
Fu S, Song S, Liu H, et al. Zika virus isolated from mosquitoes: a field and laboratory investigation in China, 2016. Sci China Life Sci 2017 (published online Oct 19)
Gardner L, Chen N, Sarkar S. Vector status of Aedes species determines geographical risk of autochthonous Zika virus establishment. PLoS Negl Trop Dis 2017 Mar 24;11(3):e0005487
Gendernalik A, Weger-Lucarelli J, Luna SMG, et al. American Aedes vexans mosquitoes are competent vectors of Zika virus. Am J Trop Med Hyg 2017 (published online Mar 13)
Goertz GP, Vogels CBF, Geertsema C, et al. Mosquito co-infection with Zika and chikungunya virus allows simultaneous transmission without affecting vector competence of Aedes aegypti. PLoS Negl Trop Dis 2017 Jun 1;11(6): e0005654
Gridley-Smith CL. Examining mosquito surveillance and control capacity in the top 10 areas at risk for Zika virus exposure in the United States. J Public Health Manag Pract 2017 Aug;23(5):515-7
Guedes DRD, Paiva MHS, Donato MMA, et al. Zika virus replication in the mosquito Culex quinquefasciatus in Brazil. Emerg Microbes Infect 2017 (published online Aug 9)
Hahn MB, Eisen L, McAllister J, et al. Updated reported distribution of Aedes (Stegomyia) aegypti and Aedes (Stegomyia) albopictus (Diptera: Culicidae) in the United States, 1995-2016. J Med Entomol 2017 (published online Jun 19)
Heitmann A, Jansen S, Luhken R, et al. Experimental transmission of Zika virus by mosquitoes from central Europe. Eurosurveill 2017 Jan 12;22(2):pi=30437
Huang YJS, Lyons AC, Hsu WW, et al. Differential outcomes of Zika virus infection in Aedes aegypti orally challenged with infectious blood meals and infectious protein meals. PLoS One 2017 Aug 10;12(8):e0182386
Johnson TL, Haque U, Monaghan AJ, et al. Modeling the environmental suitability for Aedes (Stegomyia) aegypti and Aedes (Stegomyia) albopictus (diptera: Culicidae) in the contiguous United States. J Med Entomol 2017 (published online Sep 21)
Kollars TM. Assessing likely invasion sites of Zika virus-infected mosquitoes in civilian and naval maritime ports in Florida. Res Rep Trop Med 2017 Jan 7;8:1-6
Kotsakiozi P, Gloria-Soria A, Caccone A, et al. Tracking the return of Aedes aegypti to Brazil, the major vector of the dengue, chikungunya and Zika viruses. PLoS Negl Trop Dis 2017 Jul 25;11(7):e0005653
Leal WS, Barbosa RMR, Zeng F, et al. Does Zika virus infection affect mosquito response to repellents? Sci Rep 2017 (published online Feb 16)
Liu Y, Liu J, Du S, et al. Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes. (Letter) Nature 2017 (published online May 17)
Lourenco-de-Oliveira R, Marques JT, Sreenu VB, et al. Culex quinquefasciatus mosquitoes do not support replication of Zika virus. J Gen Virol 2017 (published online Oct 27)
Manni M, Guglielmino CR, Scolari F, et al. Genetic evidence for a worldwide chaotic dispersion pattern of the arbovirus vector, Aedes albopictus. PLoS Negl Trop Dis 2017 Jan 30;11(1):e0005332
Medlock JM, Vaux AGC, Cull B, et al. Detection of the invasive mosquito species Aedes albopictus in southern England. (Letter) Lancet Infect Dis 2017 Feb;17(2):140
Moyes CL, Vontas J, Martins AJ, et al. Contemporary status of insecticide resistance in the major Aedes vectors of arboviruses infecting humans. PLoS Negl Trop Dis 2017 Jul 20;11(7):e0005625
O'Donnel KL, Bixby MA, Morin KJ, et al. Potential of a northern population of Aedes vexans (Diptera: Culicidae) to transmit Zika virus. J Med Entomol 2017 (published online May 12)
Pingen M, Schmid MA, Harris E, et al. Mosquito biting modulates skin response to virus infection. Cell 2017 (published online May 8)
Pless E, Gloria-Soria A, Evans BR, et al. Multiple introductions of the dengue vector, Aedes aegypti, into California. PLoS Negl Trop Dis 2017 Aug 10;11(8):e0005718
Pruszynski CA, Hribar LJ, Mickle R, et al. A large scale biorational approach using Bacillus thuringiensis israeliensis (strain AM65-52) for managing Aedes aegypti populations to prevent dengue, chikungunya and Zika transmission. PLoS One 2017 Feb 15;12(2):e0170079
Roundy CM, Azar SR, Rossi SL, et al. Variation in Aedes aegypti mosquito competence for Zika virus transmission. Emerg Infect Dis. 2017 (published online Feb 28)
Ruckert C, Weger-Lucarelli J, Garcia-Luna SM, et al. Impact of simultaneous exposure to arboviruses on infection and transmission by Aedes aegypti mosquitoes. Nat Commun 2017 (published online May 19)
Saldana MA, Etebari K, Hart CE, et al. Zika virus alters the microRNA expression profile and elicits an RNAi response in Aedes aegypti mosquitoes. PLoS Negl Trop Dis 2017 Jul 17;11(7):e0005760
Secundino NFC, Chaves BA, Orfano AS, et al. Zika virus transmission to mouse ear by mosquito bite: a laboratory model that replicates the natural transmission process. Parasit Vectors 2017 (published online Jul 20)
Smartt CT, Stenn TMS, Chen TY, et al. Evidence of Zika virus RNA fragments in Aedes albopictus (Diptera: Culicidae) field-collected eggs from Camacari, Bahia, Brazil. J Med Entomol 2017 (published online Apr 14)
Schmidt TL, Barton NH, Rasic G, et al. Local introduction and heterogeneous spatial spread of dengue-suppressing Wolbachia through an urban population of Aedes aegypti. PLoS Biol 2017 May 30;15(5):e2001894
Song S, Li Y, Fu S, et al.
Could Zika virus emerge in mainland China? Virus isolation from nature in Culex quinquefasciatus, 2016. Emerg Microbes Infect 2017 (published online Nov 1)
Trewin BJ, Darbro JM, Jansen CC, et al.
The elimination of the dengue vector, Aedes aegypti, from Brisbane, Australia: the role of surveillance, larval habitat removal and policy. PLoS Negl Trop Dis 2017 Aug 28;11(8):e0005848
Varjak M, Donald CL, Mottram TJ, et al.
Characterization of the Zika virus induced small RNA response in Aedes aegypti cells. PLoS Negl Trop Dis 2017 Oct 17;11(10):e0006010
Watts AG, Miniota J, Joseph HA, et al.
Elevation as a proxy for mosquito-borne Zika virus transmission in the Americas. PLoS One 2017 May 24;12(5):e0178211

Virus Detection

Afsahi S, Lerner MB, Goldstein JM, et al. Novel graphene-based biosensor for early detection of Zika virus infection. Biosens Bioelectron 2017 (published online Aug 24)
Balmaseda A, Stettler K, Medialdea-Carrera R, et al. Antibody-based assay discriminates Zika virus infection from other flaviviruses. PNAS 2017 (published online Jul 17)
Bosch I, de Puig H, Hiley M, et al.
Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum. Sci Transl Med 2017 (published online Sep 27)
Calvert AE, Biggerstaff BJ, Tanner NA, et al.
Rapid colorimetric detection of Zika virus from serum and urine specimens by reverse transcription loop-mediated isothermal amplification (RT-LAMP). PLoS One 2017 Sep 25;12(9):e0185340
Chotiwan N, Brewster CD, Magalhaes T, et al.
Rapid and specific detection of Asian- and African-lineage Zika viruses. Sci Transl Med 2017 May 3;9(388):eaag0538
Coffey LL, Pesavento PA, Keesler RI, et al. Zika virus tissue and blood compartmentalization in acute infection of rhesus macaques. PLoS One 2017 Jan 31;12(1):e0171148
Froeschl G, Huber K, von Sonnenburg F, et al. Long-term kinetics of Zika virus RNA and antibodies in body fluids of a vasectomized traveller returning from Martinique: a case report. BMC Infect Dis 2017 Jan 10;17:55
Jiang Q, Chandar YJ, Cao S, et al. Rapid, point-of-care, paper-based plasmonic biosensor for Zika virus diagnosis. Adv Biosyst 2017 (published online Aug 10)
Lee AJ, Bhattacharya R, Scheuermann RH, et al.  Identification of diagnostic peptide regions that distinguish Zika virus from related mosquito-borne Flaviviruses. PLoS One 2017 May 31;12(5):e0178199.
Olschlager S, Enfissi A, Zaruba M, et al. Diagnostic validation of the RealStar Zika virus reverse transcription polymerase chain reaction kit for detection of Zika virus RNA in urine and serum specimens. Am J Trop Med Hyg 2017 Oct;97(4):1070-1
Passos SRL, dos Santos MAB, Cerbino-Neto J, et al. Detection of Zika virus in April 2013 patient samples, Rio de Janeiro, Brazil. Emerg Infect Dis 2017 (published online Sep 27)
Penot P, Brichler S, Guilleminot J, et al. Infectious Zika virus in vaginal secretions from an HIV-infected woman, France, August 2016. Eurosurveill 2017 Jan 19;22(3):pii=30444
Russell S, Ryff K, Gould C, et al. Detecting local Zika virus transmission in the continental United States: a comparison of surveillance strategies. PLoS Curr 2017 Nov 22
Rodriguez-Valero N, Borobia AM, Lago M, et al. Zika virus screening among Spanish team members after 2016 Rio de Janeiro, Brazil, Olympic Games. Emerg Infect Dis 2017 (published online Jun 19)
Rossini G, Gaibani P, Vocale C, et al. Comparison of Zika virus (ZIKV) RNA detection in plasma, whole blood and urine — case series of travel-associated ZIKV infection imported to Italy, 2016. J Infect 2017 (published online Jun 22)
Safronetz D, Sloan A, Stein DR, et al. Evaluation of 5 commercially available Zika virus immunoassays. Emerg Infect Dis 2017 (published online Jun 30)
Subissi L, Daudens-Vaysse E, Cassadou S, et al. Revising rates of asymptomatic Zika virus infections based on sentinel surveillance data from French overseas territories. Int J Infect Dis 2017 (published online Oct 25)
Tsai WY, Youn HH, Brites C, et al. Distinguishing secondary dengue virus infection from Zika virus infection with previous dengue by a combination of three simple serological tests. Clin Infect Dis 2017 (published online Jul 29)
Vouga M, Musso D, Schuab B, et al. Zika virus: are we going too far? (Letter) Lancet 2017 (published online Jan 14)
Weaver SC. Emergence of epidemic Zika virus transmission and congenital Zika syndrome: are recently evolved traits to blame? mBio 2017 Jan 10;8(1):e02063-16
Wilson HL, Tran T, Druce J, et al. A neutralization assay for Zika and Dengue viruses using a real-time PCR-based endpoint assessment. J Clin Microbiol 2017 (published online Aug 9)
Zuanazzi D, Arts EJ, Jorge PK, et al. Postnatal identification of Zika virus peptides from saliva. J Dent Res 2017 (published online Aug 21)

Virus Traits/Structure/Mutations/Actions

Aldunate F, Gambaro F, Fajardo A, et al. Evidence of increasing diversification of Zika virus strains isolated in the American continent. J Med Virol 2017 (published online Aug 9)
Amorim R, Temzi A, Griffin BD, et al.
Zika virus inhibits eIF2α-dependent stress granule assembly. PLoS Negl Trop Dis 2017 Jul 17;11(7):e0005775
Barreto-Vieira DF, Jacome FC, da Silva MAN, et al.
Structural investigation of C6/36 and Vero cell cultures infected with a Brazilian Zika virus. PLoS One 2017 Sep 12;12(9):e0184397
Best K, Guedj J, Madelain V, et al.
Zika plasma viral dynamics in nonhuman primates provides insights into early infection and antiviral strategies. Proc Natl Acad Sci USA 2017 (published online Aug 1)
Bowen JR, Quicke KM, Maddur MS, et al.
Zika virus antagonizes type 1 interferon responses during infection of human dendritic cells. PLoS Pathog 2017 Feb 2;13(2):e1006164
Chavali PL, Stojic L, Meredith LW, et al. Neurodevelopmental protein Musashi 1 interacts with the Zika genome and promotes viral replication. Science 2017 (published online Jun 1)
Cortese M, Goellner S, Acosta EG, et al. Ultrastructural characterization of Zika virus replication factories. Cell Rep 2017 Feb 28;18(9):2113-23

Dowall SD, Graham VA, Rayner E, et al. Lineage-dependent differences in the disease progression of Zika virus infection in type-I interferon receptor knockout (A129) mice. PLoS Negl Trop Dis 2017 Jul 3;11(7):e0005704
Fontes-Garfias CR, Shan C, Luo H, et al. Functional analysis of glycosylation of Zika virus envelope protein. Cell Rep 2017 (published online Oct 31)
Foo SS, Chen W, Chan Y, et al. Asian Zika virus strains target CD14+ blood monocytes and induce M2-skewed immunosuppression during pregnancy. Nat Microbiol 2017 (published online Aug 21)
Hou W, Armstrong N, Obwolo LA, et al. Determination of the cell permissiveness spectrum, mode of RNA replication, and RNA-protein interaction of Zika virus. BMC Infect Dis 2017 Mar 31;17:239
Jurado KA, Yockey LJ, Wong PW, et al. Antiviral CD8 T cells induce Zika-virus-associated paralysis in mice. Nat Microbiol 2017 (published online Nov 20)

Kam YW, Leite JA, Lum FM, et al. Specific biomarkers associated with neurological complications and congenital CNS abnormalities from Zika virus-infected patients in Brazil. J Infect Dis 2017 (published online May 30)
Lai L, Rouphael N, Xu Y, et al. Innate, T and B cell responses in acute human Zika patients. Clin Infect Dis 2017 (published online Aug 17)
McLinden JH, Bhattarai N, Stapleton JT, et al. Yellow fever virus, but not Zika or Dengue virus inhibits T cell receptor-mediated T cell function by an RNA-based mechanism. J Infect Dis 2017 (published online Sep 2)
Metz SW, Gallichotte EN, Brackbill A, et al. In vitro assembly and stabilization of dengue and Zika virus envelope protein Homo-Dimers. Sci Rep 2017 (published online Jul 3)
Michlmayr D, Andrade P, Gonzalez K, et al. CD14+CD16+ monocytes are the main target of Zika virus infection in peripheral blood mononuclear cells in a paediatric study in Nicaragua. (Letter) Nat Microbiol 2017 (published online Oct 2)
Miner JJ, Diamond MS. Zika virus pathogenesis and tissue tropism. Cell Host Microbe 2017 Feb 8;21(2):134-42

Monel B, Compton AA, Bruel T, et al. Zika virus induces massive cytoplasmic vacuolization and paraptosis‐like death in infected cells. EMBO J 2017 (published online May 4)
Oh Y, Zhang F, Wang Y, et al. Zika virus directly infects peripheral neurons and induces cell death. Nat Neurosci 2017 (published online Jul 31)

Pagani, Ghezzi S, Ulisse A, et al. Human endometrial stromal cells are highly permissive to productive infection by Zika virus. Sci Rep 2017 (published online Mar 10)
Pardy RD, Rajah MM, Condotta SA, et al. Analysis of the T cell response to Zika virus and identification of a novel CD8+ T cell epitome in immunocompetent mice. PLoS Pathog 2017 Feb 13;13(2):e1006184
Peralta-Aros C, García-Nieto V. Does Zika virus infection induce prolonged remissions in children with idiopathic nephrotic syndrome? Pediatr Nephrol 2017 (published online Feb 7)
Prasad VM, Miller AS, Klose T, et al.Structure of the immature Zika virus at 9 Angstrom resolution. Nat Struct Mol Biol 2017 (published online Jan 9)

Richard AS, Shim BS, Kwon YC, et al. AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses. Proc Natl Acad Sci USA 2017 (published online Feb 6)
Rogers TF, Goodwin EC, Briney B, et al. Zika virus activates de novo and cross-reactive memory B cell responses in dengue-experienced donors. Sci Immunol 2017 (published online Aug 18)
Saldana MA, Etebari K, Hart CE, et al. Zika virus alters the microRNA expression profile and elicits an RNAi response in Aedes aegypti mosquitoes. PLoS Negl Trop Dis 2017 Jul 17;11(7):e0005760
Siddharthan V, Van Wettere AJ, Li R, et al. Zika virus infection of adult and fetal STAT2 knock-out hamsters. Virology 2017 (published online Apr 18)
Terzian ACB, Schanoski AS, de Oliveira Mota MT, et al. Viral load and cytokine response profile does not support antibody-dependent enhancement in dengue-primed Zika-infected patients. Clin Infect Dis 2017 (published online Jun 20)
Tripathi S, Balasubramaniam VRMT, Brown JA, et al. A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses. PLoS Pathog 2017 Mar 9;13(3):e1006258
Varjak M, Donald CL, Mottram TJ, et al.
Characterization of the Zika virus induced small RNA response in Aedes aegypti cells. PLoS Negl Trop Dis 2017 Oct 17;11(10):e0006010
Yokoyama S, Starmer WT.
Possible roles of new mutations shared by Asian and American Zika viruses. Mol Biol Evol 2017 (published online Jan 12)
Yuan L, Huang XY, Liu ZY, et al. A single mutation in the prM protein of Zika virus contributes to fetal microcephaly. Science 2017 (published online Sep 28)
Zhao B, Yi G, Du F, et al. Structure and function of the Zika virus full-length NS5 protein. Nat Commun 2017 (published online Mar 27)

Zika and Other Pathogens

Andrade DV, Harris E. Recent advances in understanding the adaptive immune response to Zika virus and the effect of previous flavivirus exposure. Virus Res 2017 (published online Jun 26)
Bosch I, de Puig H, Hiley M, et al. Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum. Sci Transl Med 2017 (published online Sep 27)
Braga JU, Bressan C, Dalvi APR, et al.
Accuracy of Zika virus disease case definition during simultaneous dengue and chikungunya epidemics. PLoS One 2017 Jun 26;12(6):e0179725
Cevallos V, Ponce P, Waggoner JJ, et al. Zika and Chikungunya virus detection in naturally infected Aedes aegypti in Ecuador. Acta Trop 2017 (published online Oct 2)
Collins MH, McGowan E, Jadi R, et al. Lack of durable cross-neutralizing antibodies against Zika virus from dengue virus infection. Emerg Infect Dis 2017 (published online Mar 27)
Fernandez E, Dejnirattisai W, Cao B, et al.
Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection. Nat Immunol 2017 (published online Sep 25)
George J, Valiant WG, Mattapallil MJ, et al. Prior exposure to Zika virus significantly enhances peak dengue-2 viremia in rhesus macaques. Sci Rep 2017 (published online Sep 5)
Goertz GP, Vogels CBF, Geertsema C, et al. Mosquito co-infection with Zika and chikungunya virus allows simultaneous transmission without affecting vector competence of Aedes aegypti. PLoS Negl Trop Dis 2017 Jun 1;11(6): e0005654
Grifoni A, Pham J, Sidney J, et al. Prior dengue virus exposure shapes T cell immunity to Zika virus in humans. J Virol 2017 (published online Oct 4)
Halai UA, Nielsen-Saines K, Moreira ME, et al. Maternal Zika virus disease severity, virus load, prior dengue antibodies and their relationship to birth outcomes.Clin Infect Dis 2017 (published online May 23)
Ho HJ, Wong JGX, Kyaw WM, et al. Diagnostic accuracy of parameters for Zika and dengue virus infections, Singapore. Emerg Infect Dis 2017 (published online Nov 2)
Lee AJ, Bhattacharya R, Scheuermann RH, et al.  Identification of diagnostic peptide regions that distinguish Zika virus from related mosquito-borne Flaviviruses. PLoS One 2017 May 31;12(5):e0178199.
McCracken MK, Gromowski GD, Friberg HL, et al. Impact of prior flavivirus immunity on Zika virus infection in rhesus macaques. PLoS Pathog 2017 Aug 3;13(8):e1006487
McDonald EM, Duggal NK, Brault AC. Pathogenesis and sexual transmission of Spondweni and Zika viruses. PLoS Negl Trop Dis 2017 Oct 6;11(10):e0005990.
McLinden JH, Bhattarai N, Stapleton JT, et al. Yellow fever virus, but not Zika or Dengue virus inhibits T cell receptor-mediated T cell function by an RNA-based mechanism. J Infect Dis 2017 (published online Sep 2)
Moni MA, Lio P. Genetic profiling and comorbidities of Zika infection. J Infect Dis 2017 (published online Jul 27)
Moreno-Madrinan MJ, Turell M. Factors of concern regarding Zika and other Aedes aegypti-transmitted viruses in the United States. J Med Entomol 2017 (published online Jan 3)
Neaterour P, Rivera A, Galloway RL, et al. Fatal Leptospira spp./Zika virus coinfection — Puerto Rico, 2016. Am J Trop Med Hyg 2017 (published online Jun 26)
Pantoja P, Perez-Guzman EX, Rodriguez IV, et al. Zika virus pathogenesis in rhesus macaques is unaffected by pre-existing immunity to dengue virus. Nat Commun 2017 (published online Jun 23)
Riou J, Poletto C, Boelle PY. A comparative analysis of chikungunya and Zika transmission. bioRxiv 2017 Jan 29
Sariol CA, Nogueira ML, Vasilakis N. A tale of two viruses: does heterologous flavivirus immunity enhance Zika disease? Trends Microbiol 2017 (published online Nov 6)
Suwanmanee S, Luplertlop N. Dengue and Zika viruses: lessons learned from the similarities between these Aedes mosquito-vectored arboviruses. J Microb 2017 (published online Jan 26)
Terzian ACB, Schanoski AS, de Oliveira Mota MT, et al. Viral load and cytokine response profile does not support antibody-dependent enhancement in dengue-primed Zika-infected patients. Clin Infect Dis 2017 (published online Jun 20)
Tsai WY, Youn HH, Brites C, et al. Distinguishing secondary dengue virus infection from Zika virus infection with previous dengue by a combination of three simple serological tests. Clin Infect Dis 2017 (published online Jul 29)
Vazquez-Calvo A, Blazquez AB, Escribano-Romero E, et al. Zika virus infection confers protection against West Nile virus challenge in mice. Emerg Microb Infect 2017 (published online Sep 20)
Wen J, Ngono AE, Regla-Nava JA, et al. Dengue virus-reactive CD8+ T cells mediate cross-protection against subsequent Zika virus challenge. Nat Commun 2017 (published online Nov 13)

2016

Acharya D, Bastola P, Le L, et al. An ultrasensitive electrogenerated chemiluminescence-based immunoassay for specific detection of Zika virus. Sci Rep 2016 (published online Aug 24)
Adams Waldorf KM, Stencel-Baerenwald JE. Kapur RP, et al. Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate. Nat Med 2016 (published online Sep 12)
Adcock RS, Chu YK, Golden JE, et al. Evaluation of anti-Zika virus activities of broad-spectrum antivirals and NIH clinical collection compounds using a cell-based, high-throughput screen assay. Antiviral Res 2016 (published online Dec 3)
Adibi JJ, Marques ETA Jr, Cartus A, et al. Teratogenic effects of the Zika virus and the role of the placenta. (Hypothesis). Lancet 2016 (published online Mar 4)
Ahmad SSY, Amin TN, Ustianowski A. Zika virus: management of infection and risk. BMJ 2016 (published online Feb 26)
Aiken ARA, Gomperts R, Trussell J, et al. Requests for abortion in Latin America related to concern about Zika virus exposure. (Letter) N Engl J Med 2016 (published online Jun 22)
Akiner MM, Demirci B, Babuadze G, et al. Spread of the invasive mosquitoes Aedes aegypti and Aedes albopictus in the Black Sea region increases risk of chikungunya, dengue, and Zika outbreaks in Europe. PLoS Negl Trop Dis 2016 Apr 26;10(4):e0004664
Aliota MT, Caine EA, Walker EC, et al. Characterization of lethal Zika virus infection in AG129 mice. PLoS Negl Trop Dis 2016 Apr 19;10(4):e0004682
Aliota MT, Dudley DM, Newman CM, et al. Heterologous protection against Asian ZIka virus challenge in rhesus macaques. PLoS Negl Trop Dis 2016 Dec 2;10(12):e0005168
Aliota MT, Peinado SA, Velez ID, et al. The wMel strain of Wolbachia reduces transmission of Zika virus by Aedes aegypti. Sci Rep 2016 (published online Jul 1)
Allard A, Althouse BM, Hebert-Dufresne L, et al. The risk of sustained sexual transmission of Zika is underestimated. bioRxiv 2016 Nov 30
Allen M, Blumenstock JS. Public health acts to detect, respond to, and prevent the latest public health threat — Zika virus disease. J Public Health Manage Pract 2016 Jul/Aug;22(4):424-6
Althaus CL, Low N. How relevant is sexual transmission of Zika virus? (Commentary) PLoS Med 2016 Oct 25;13(10):e1002157
Amraoui F, Atyame-Nten C, Vega-Rua A, et al. Culex mosquitoes are experimentally unable to transmit Zika virus. Euro Surveill 2016 Sep 1;21(35):pii=30333
Anaya JM, Ramirez-Santana C, Salgado-Castaneda I, et al. Zika virus and neurologic autoimmunity: the putative role of gangliosides. (Commentary) BMC Med 2016 Mar 21;14:49
Anderson KB, Thomas SJ, Endy TP. The emergence of Zika virus: a narrative review. Ann Intern Med 2016 (published online May 3)
Arias A, Torres-Tobar L, Hernandez G, et al. Guillain-Barre syndrome in patients with a recent history of Zika in Cucuta, Colombia, a descriptive case series of 19 patients from December 2015 to March 2016. J Crit Care 2016 (published online Aug 18)
Armstrong P, Hennessey M, Adams M, et al. Travel-associated Zika virus disease cases among U.S. residents — United States, January 2015-February 2016. MMWR 2016 Mar 18;65(Early release)
Arsuaga M, Bujalance SG, Diaz-Menendez M, et al. Probable sexual transmission of Zika virus from a vasectomized man. Lancet Infect Dis 2016 Oct;(16)10:1107
Arzusa-Ortega L, Polo A, Perez-Tatis G, et al. Fatal Zika virus infection in girl with sickle cell disease, Colombia. (Letter) Emerg Infect Dis (published online Jan 26, 2016)
Atieh T, Baronti C, de Lamballerie X, et al. Simple reverse genetics systems for Asian and African Zika viruses.Sci Rep 2016 (published online Dec 19)
Atkinson B, Hearn P, Afrough B, et al. Detection of Zika virus in semen. (Letter) Emerg Infect Dis 2016 (published online Feb 11)
Attar N. ZIKA virus circulates in new regions. Nature Rev Microbiol (published online Jan 11, 2016)
Aubry M, Richard V, Green J, et al. Inactivation of Zika virus in plasma with amotosalen and ultraviolet A illumination Transfusion 56(1):33-40, Jan 2016
Ayres CFJ. Identification of Zika virus vectors and implications for control. Lancet Infect Dis 2016 (published online Feb 4)
Barba-Spaeth G, Dejnirattisai W, Rouvinski A, et al. Structural basis of potent Zika–dengue virus antibody cross-neutralization. Nature 2016 (published online Jun 23)
Barcellos C, Xavier DR, Pavao A, et al. Increased hospitalizations for neuropathies as indicators of Zika virus infection, according to health information system data, Brazil. Emerg Infect Dis 2016 (published online Sept 7)
Barreto ML, Barral-Netto M, Stabeli R, et al. Zika virus and microcephaly in Brazil: a scientific agenda. Lancet 2016 (published online Feb 24)
Barton MA, Salvadori MI. Zika virus and microcephaly. (Commentary) CMAJ 2016 (published online Mar 21)
Barzon L, Pacenti M, Berto A, et al. Isolation of infectious Zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the Dominican Republic to Italy, January 2016. Euro Surveill. 2016 Mar 10;21(10):pii=30159
Barzon L, Pacenti M, Franchin E, et al. Infection dynamics in a traveler with persistent shedding of Zika virus RNA in semen for six months after returning from Haiti to Italy, January 2016. Euro Surveill 2016 Aug 11;21(32):pii=30316
Basarab M, Bowman C, Aarons EJ, et al. Zika virus. (Clinical review) BMJ 2016 (published online Feb 26)
Bastos L, Villela DAM, Carvalho LM, et al. Zika in Rio de Janeiro: assessment of basic reproductive number and its comparison with dengue. bioRxiv 2016 May 25
Basu R, Tumban E. Zika virus on a spreading spree: what we now know that was unknown in the 1950's. Virol J 2016 (published online Oct 6)
Baud D, Van Mieghem T, Musso D, et al. Clinical management of pregnant women exposed to Zika virus. (Letter) Lancet Infect Dis 2016 (published online Apr 4)
Bayless NL, Greenberg RS, Swigut T, et al. Zika virus infection induces cranial neural crest cells to produce cytokines at levels detrimental for neurogenesis. Cell Host Microb 2016 (published online Sep 29)
Beckham JD, Pastula DM, Massey A, et al. Zika virus as an emerging global pathogen: neurological complications of Zika virus. JAMA Neurol 2016 (published online May 16)
Benelli G. Spread of Zika virus: the key role of mosquito vector control. Asian Pac J Trop Biomed 2016 (published online Apr 20)
Benelli G, Canale A, Higuchi A, et al. The recent outbreaks of Zika virus: mosquito control faces a further challenge. Asian Pac J Trop Dis 2016 Apr;6(4):253-8
Besnard M, Eyrolle-Guignot D, Guillemette-Artur P, et al. Congenital cerebral malformations and dysfunction in fetuses and newborns following the 2013 to 2014 Zika virus epidemic in French Polynesia. Euro Surveill 2016 Mar 31;21(13):pii=30181
Bhatnagar J, Rabeneck DB, Martines RB, et al. Zika virus RNA replication and persistence in brain and placental tissue. Emerg Infect Dis 2016 (published online Dec 13)
Bingham AM, Cone M, Mock V, et al. Comparison of test results for Zika virus RNA in urine, serum, and saliva specimens from persons with travel-associated Zika virus disease — Florida, 2016. MMWR 2016 May 10;65(Early release)
Boccolini D, Toma L, Di Luca M, et al. Experimental investigation of the susceptibility of Italian Culex pipiens mosquitoes to Zika virus infection. Euro Surveill 2016 Sep 1;21(35):pii=30328
Bogoch II, Brady OJ, Kraemer MU, et al. Anticipating the international spread of Zika virus from Brazil. (Letter) Lancet 2016 Jan 23;387(10016):335-6
Bogoch II, Brady OJ, Kraemer MUG, et al. Potential for Zika virus introduction and transmission in resource-limited countries in Africa and the Asia-Pacific region: a modelling study. Lancet Infect Dis 2016 (published online Sep 1)
Boeuf P, Drummer HE, Richards JS, et al. The global threat of Zika virus to pregnancy: epidemiology, clinical perspectives, mechanisms, and impact. BMJ Med 2016 (published online Aug 3)
Bonaldo MC, Ribeiro IP, Lima NS, et al. Isolation of infective Zika virus from urine and saliva of patients in Brazil. PLoS Negl Trop Dis 2016 Jun 24;10(6):e0004816
Boulet SL, D'Angelo DV, Brian Morrow B, et al. Contraceptive use among nonpregnant and postpartum women at risk for unintended pregnancy, and female high school students, in the context of Zika preparedness — United States, 2011-2013 and 2015. MMWR 2016 Aug 2;65(Early release)
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Reiter P. Control of urban Zika vectors: should we return to the successful PAHO/WHO strategy? (Commentary) PLoS Negl Trop Dis 2016 Jun 1;10(6):e0004769
Retallack H, Di Lullo E, Arias C, et al. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. Proc Natl Acad Sci USA 2016 (published online Nov 29)
Reusken C, Pas S, GeurtsvanKessel C, et al. Longitudinal follow-up of Zika virus RNA in semen of a traveller returning from Barbados to the Netherlands with Zika virus disease, March 2016. Euro Surveill 2016 Jun 8;21(23):pii=30251
Reznik SE, Ashby CR Jr. Sofosbuvir: an anti-viral drug with potential efficacy against Zika infection. Int J Infect Dis 2016 (published online Dec 14)
Ribeiro LS, Marques RE, Ribeiro de Jesus AM, et al. Zika crisis in Brazil: challenges in research and development. Curr Opin Virol 2016 (published online May 12)
Rojas DP, Dean NE, Yang Y, et al. The epidemiology and transmissibility of Zika virus in Girardot and San Andres Island, Colombia. bioRxiv 2016 Apr 24
Rojas DP, Dean NE, Yang Y, et al. The epidemiology and transmissibility of Zika virus in Girardot and San Andres island, Colombia, September 2015 to January 2016. Euro Surveill 2016 Jul 14;21(28):pii=30283
Rosa R, Abbo LM, Kapur G, et al.Development and implication of a Zika virus disease response protocol at a large academic medical center. Disaster Med Public Health Prep 2016 (published online Jul 19)
Rosenberg R. Threat from emerging vectorborne viruses. (Commentary) Emerg Infect Dis 2016 (published online Mar 22)
Rossi SL, Tesh RB, Azar SR, et al. Characterization of a novel murine model to study Zika virus. Am J Trop Med Hyg 2016 (published online Mar 28)
Roze B, Najioullah F, Ferge J, et al. Zika virus detection in urine from patients with Guillain-Barre syndrome on Martinique, January 2016. Euro Surveill 2016;21(9):pii=30154
Rubin EJ, Greene MF, Baden LR. Zika virus and microcephaly. (Editorial) N Engl J Med 2016 (published online Feb 10)
Russell K, Hills SL, Oster AM, et al. Male-to-female sexual transmission of Zika virus — United States, January-April 2016. Clin Infect Dis 2016 (published online Oct 19)
Russell K, Oliver SE, Lewis L, et al. Interim guidance for the evaluation and management of infants with possible congenital Zika virus infection — United States, August 2016. (Update) MMWR 2016 Aug 19;65
Russell PK.
The Zika pandemic — a perfect storm? (Editorial) PLoS Negl Trop Dis 2016 Mar 18;10(3):e0004589
Saad-Roy CM, van den Driessche P, Ma J. Estimation of Zika virus prevalence by appearance of microcephaly. BMC Infect Dis 2016 Dec 12;16:754
Sacramento CQ, de Melo GR, Rocha N, et al. The clinically approved antiviral drug sofosbuvir impairs Brazilian zika virus replication. bioRxiv 2016 Jul 6
Saenz C. Zika virus: ethics preparedness for old and new challenges. (Letter) Lancet Glob Health 2016 Oct;4(10):e686
Salinas S, Erkilic N, Damodar K, et al.Zika virus efficiently replicates in human retinal pigment epithelium and disturbs its permeability. J Virol 2016 (published online Nov 16)
Samarasekera U, Triunfol M. Concern over Zika virus grips the world. (Special report) Lancet 2016 (published online Feb 2)
Sapparapu G, Fernandez E,  Kose N, et al. Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice. (Letter) Nature 2016 (published online Nov 7)
Sardi S, Somasekar S, Naccache SN, et al. Co-infections from Zika and chikungunya virus in Bahia, Brazil identified by metagenomic next-generation sequencing. J Clin Microbiol (published online Jul 13)
Sarmiento-Ospina A, Vasquez-Serna, Jimenez-Canizales CE, et al.
Zika virus associated deaths in Colombia. Lancet Infect Dis 2016 (published online Apr 7)
Sarno M, Aquino M, Pimentel K, et al.
Progressive lesions of central nervous system in microcephalic fetuses with suspected congenital Zika virus syndrome. Ultrasound Obstet Gynecol 2016 (published online Sep 19)
Sarno M, Sacrament GA, Khouri R, et al. Zika virus infection and stillbirths: a case of hydrops fetalis, hydranencephaly and fetal demise. PLoS Negl Trop Dis 2016 Feb 25;10(2):e0004517
Savidis G, Perreira JM, Portmann JM, et al. The IFITMs inhibit Zika virus replication. Cell Rep 2016 (published online Jun 3)
Schneider ADB, Malone RW, Guo JT, et al. Molecular evolution of Zika virus as it crossed the Pacific to the Americas. Cladistics 2016 (published online Dec 13)
Schuck-Paim C, Lopez D, Simonsen L, et al. Unintended pregnancies in Brazil — a challenge for the recommendation to delay pregnancy due to Zika. PLoS Curr 2016 (published online Mar 16)
Schuler-Faccini L, da Silva AA, Vianna FSL, et al. Defining the Zika virus embryopathy phenotype. Reproduct Toxicol 2016 (published online May 10)
Schuler-Faccini L, Ribeiro EM, Feitosa IML, et al. Possible association between Zika virus infection and microcephaly — Brazil, 2015. MMWR 2016;65(3):1-4
Schwarz MC, Sourisseau M, Espino MM, et al. Rescue of the 1947 Zika virus prototype strain with a cytomegalovirus promoter-driven cDNA clone. mSphere 2016 (published online Oct 3)
Septfons A, Leparc-Goffart I, Couturier E, et al. Travel-associated and autochthonous Zika virus infection in mainland France, 1 January to 15 July 2016. Euro Surveill 2016 Aug 11;21(32):pii=30315
Shan C, Xie X, Muruato AE, et al. An infectious cDNA clone of Zika virus to study viral virulence, mosquito transmission, and antiviral inhibitors. Cell Host Microb 2016 (published online May 16)
Sharp TM, Munoz-Jordan J, Perez-Padilla J, et al. Zika virus infection associated with severe thrombocytopenia. Clin Infect Dis 2016 (published online Jul 14)
Shen S, Shi J, Wang J, et al. Phylogenetic analysis revealed the central roles of two African countries in the evolution and worldwide spread of Zika virus. Virol Sin 2016 Apr;31(2):118-30
Shi W, Zhang Z, Ling C, et al. Increasing genetic diversity of Zika virus in the Latin American outbreak. (Letter) Emerg Microb Infect 2016 (published online Jul 6)
Shinohara K, Kutsuna S, Takasaki T, et al. Zika fever imported from Thailand to Japan, and diagnosed by PCR in the urine. J Travel Med 2016 Jan 18;23(1). pii:tav011
Simeone RM, Shapiro-Mendoza CK, Meaney-Delman D, et al. Possible Zika virus infection among pregnant women — United States and territories, May 2016. MMWR 2016 May 20;65(Early release)
Sirohi D, Chen Z, Sun L, et al. The 3.8 Angtrom resolution cryo-EM structure of Zika virus. Science 2016 (published online Mar 31)
Soares CN, Brasil P, Carrera RM, et al. Fatal encephalitis associated with Zika Virus infection in an adult. J Clin Virol 2016 (published online Aug 30)
Soares de Araujo JS, Regis CT, Gomes RGS, et al. Microcephaly in northeast Brazil: a review of 16 208 births between 2012 and 2015. [Submitted] Bull World Health Organ 2016 (posted online Feb 4)
Soares de Oliveira-Szejnfeld P, Levine D, Melo ASO, et al.
Congenital brain abnormalities and Zika virus: what the radiologist can expect to see prenatally and postnatally. Radiology 2016 (published online Aug 24)
Solomon T, Baylis M, Brown D. Zika virus and neurological disease—approaches to the unknown. Lancet Infect Dis 2016 (published online Feb 25)
Song H, Qi J, Haywood J, et al. Zika virus NS1 structure reveals diversity of electrostatic surfaces among flaviviruses. Nat Struct Mol Biol 2016 (published online Apr 18)
Song J, Mauk MG, Hackett BA, et al. Instrument-free point-of-care molecular detection of Zika virus. Anal Chem 2016 (published online Jun 16)
Southwell BG, Dolina S, Jimenez-Magdaleno K, et al. Zika virus–related news coverage and online behavior, United States, Guatemala, and Brazil. (Letter) Emerg Infect Dis 2016 (published online Apr 21)
Souto IO, Alejo-Cancho I, Brustenga JG, et al. Persistence of ZIka virus in semen 93 days after the onset of symptoms. Inferm Infecc Microbiol Clin 2016 (published online Dec 19)
Sow A, Loucoubar C, Diallo D, et al. Concurrent malaria and arbovirus infections in Kedougou, southeastern Senegal. Malar J 2016 Jan 28;15(1):47
Staples JE, Dziuban EJ, Fischer M, et al. Interim guidelines for the evaluation and testing of infants with possible congenital Zika virus infection — United States, 2016. MMWR 2016; 65(3);1-5
Stauft CB, Gorbatsevych O, Cello J, et al. Comparison of African, Asian, and American Zika viruses in Swiss Webster mice: virulence, neutralizing antibodies, and serotypes. bioRxiv 2016 Sep 19
Steinhagen K, Probst C, Radzimski C, et al. Serodiagnosis of Zika virus (ZIKV) infections by a novel NS1-based ELISA devoid of cross-reactivity with dengue virus antibodies: a multicohort study of assay performance, 2015 to 2016. Eurosurveill 2016 Dec 15;(21)50:pii=30426
Stettler K, Beltramello M, Espinosa DA, et al. Specificity, cross-reactivity and function of antibodies elicited by Zika virus infection. Science 2016 (published online Jul 14)
St. George K, Sohi IS, Dufort EM, et al. Zika virus testing considerations: lessons learned from the first eighty real-time RT-PCR-positive cases diagnosed in New York State. J Clin Microbiol 2016 (published online Dec 7)
Sun J, Wu D, Zhong H, et al. Presence of Zika virus in conjunctival fluid. JAMA Ophthalmol 2016 (published online Sep 15)
Swanstrom JA, Plante JA, Plante JA, et al. Dengue virus envelope dimer epitope monoclonal antibodies isolated from Dengue patients are protective against Zika Virus. mBio 2016 (published online Jul 19)
Tabata T, Petitt M, Puerta-Guardo H, et al. Zika virus targets different primary human placental cells, suggesting two routes for vertical transmission. Cell Host Microb 2016 (published online Jul 18)
Tang BL. Zika virus as a causative agent for primary microencephaly: the evidence so far. Arch Microbiol 2016 (published online Jul 13)
Tang H, Hammack C, Ogden SC, et al.
Zika virus infects human cortical neural progenitors and attenuates their growth. Cell Stem Cell 2016 (published online Mar 4)
Tang WW, Young MP, Mamidi A, et al. A  mouse model of Zika virus sexual transmission and vaginal viral replication. Cell Rep 2016 Dec 20;17(12):3091-8
Tepper NK, Goldberg HI, Bernal MIV, et al. Estimating contraceptive needs and increasing access to contraception in response to the Zika virus disease outbreak — Puerto Rico, 2016. MMWR 2016 Mar 25;65(Early release)
Thomas DL, Sharp TM, Torres J, et al. Local transmission of Zika virus — Puerto Rico, November 23, 2015-January 28, 2016. MMWR 2016 Feb 12;65(6):1-6
Thomas SJ, L'Azou M, Barrett ADT, et al. Fast-track Zika vaccine development — is it possible? (Commentary) N Engl J Med 2016 Sep 29;375(13):1212-6
Tian H, Ji X, Yang X, et al. Structural basis of Zika virus helicase in recognizing its substrates. Protein Cell 2016 (published online Jul 18)
Tian H, Ji X, Yang X, et al. The crystal structure of Zika virus helicase: basis for antiviral drug design. (Letter) Protein Cell 2016 (published online May 12)
Tsetsarkin KA, Kenney H, Chen R, et al.
A full-length infectious cDNA clone of Zika virus from the 2015 epidemic in Brazil as a genetic platform for studies of virus-host interactions and vaccine development. mBio 2016 Aug 23;7(4):e01114-16
Turmel JM, Abgueguen P, Hubert B, et al. Late sexual transmission of Zika virus related to persistence in the semen. (Letter) Lancet 2016 (published online Jun 7)
van der Eijk AA, van Genderen PJ, Verdijk RM, et al. Miscarriage associated with Zika virus infection. (Letter) N Engl J Med 2016 (published online Jul 27)
van der Linden V, Filho ELR, Lins OG, et al. Congenital Zika syndrome with arthrogryposis: retrospective case series study. BMJ 2016 (published online Aug 9)
van der Linden V, Pessoa A, Dobyns W, et al. Description of 13 infants born during October 2015-January 2016 with congenital Zika virus infection without microcephaly at birth — Brazil. MMWR 2016 Nov 22;65(Early release)
Van Esbroeck M, Meersman K, Michiels J, et al. Specificity of Zika virus ELISA: interference with malaria. (Letter) Euro Surveill 2016 May 26;21(21):pii=30237
Van Kerkhove MD, Reveiz L, Souza JP, et al. Harmonisation of Zika virus research protocols to address key public health concerns. (Letter) Lancet Glob Health 2016 (published online Nov 3)
Vasquez AM, Sapiano MR, Basavaraju SV, et al. Survey of blood collection centers and implementation of guidance for prevention of transfusion-transmitted Zika virus infection — Puerto Rico, 2016. MMWR 2016 Apr 8;65
Ventura CV, Maia M, Bravo-Filho V, et al. Zika virus in Brazil and macular atrophy in a child with microcephaly. Lancet 2016 (published online Jan 7)
Ventura CV, Maia M, Dias N, et al. Zika: neurological and ocular findings in infant without microcephaly. (Letter) Lancet 2016 (published online Jun 7)
Ventura CV, Maia M, Ventura BV, et al. Ophthalmological findings in infants with microcephaly and presumable intra-uterus Zika virus infection. Arq Bras Oftalmol 2016 Feb;79(1):1-3
Venturi G, Zammarchi L, Fortuna C, et al. An autochthonous case of Zika due to possible sexual transmission, Florence, Italy, 2014. Euro Surveill 2016 Feb 25;21(8):pii=30148
Victora CG, Schuler-Faccini L, Matijasevich A, et al. Microcephaly in Brazil: how to interpret reported numbers? (Commentary) Lancet 2016 (published online Feb 6)
Villamil-Gomez WE, Gonzalez-Camargo O, Rodriguez-Ayubi J, et al. Dengue, chikungunya and Zika co-infection in a patient from Colombia. J Infect Public Health 2016 (published online Jan 2)
Villamil-Gomez WE, Mendoza-Guete A, Villalobos E, et al. Diagnosis, management and follow-up of pregnant women with Zika virus infection: a preliminary report of the ZIKERNCOL cohort study on Sincelejo, Colombia. Travel Med Infect Dis 2016 (published online Mar 4)
Vinhaes ES, Santos LA, Dias L, et al. Transient hearing loss in adults associated with Zika virus infection. Clin Infect Dis 2016 (published online Dec 7)
Vorona GA, Lanni SM. Fetal MRI evaluation of a 21 week fetus with Zika virus infection. Pediatr Neurol 2016 (published online Jul 30)
Vorou R. Zika virus, vectors, reservoirs, amplifying hosts, and their potential to spread worldwide: what we know and what we should investigate urgently. Int J Infect Dis 2016 (published online May 18)
Waddell LA, Greig JD. Scoping review of the Zika virus literature. PLoS One 2016 May 31;11(5):e0156376
Waggoner JJ, Gresh L, Mohamed-Hadley A, et al. Single-reaction multiplex PCR for detection of Zika, chikungunya, and dengue viruses. Emerg Infect Dis 2016 (published online Apr 25)
Waggoner JJ, Pinsky BA. Zika virus: diagnostics for an emerging pandemic threat. J Clin Microbiol 2016 (published online Feb 17)
Wang L, Valderramo SG, Wu A, et al. From mosquitos to humans: genetic evolution of Zika virus. (Commentary) Cell Host Microb 2016 (published online Apr 16)Wang Q, Yang H, Liu X, et al. Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus. Sci Transl Med 2016 Dec 14;(8)369:ra179
Weger-Lucarelli J, Duggal NK, Bullard-Feibelman K, et al. Development and characterization of recombinant virus generated from a new world Zika virus infectious clone. J Virol 2016 (published online Oct 19)
Weisblum Y, Oiknine-Djian E, Vorontsov OM, et al. Zika virus infects early- and mid-gestation human maternal-decidual tissues, inducing distinct innate tissue responses in the maternal-fetal interface. J Virol 2016 (published online Dec 14)
Wikan N, Smith DR. Zika virus: history of a newly emerging arbovirus. Lancet Infect Dis 2016 (published online Jun 6)
Wilson ME, Schlagenhauf P.Aedes and the triple threat of DENV, CHIKV, ZIKV — arboviral risks and prevention at the 2016 Rio Olympic games. Travel Med Infect Dis 2016 (published online Jan 29)
Wiwanitkit S, Wiwanitkit V. Afebrile, asymptomatic and non-thrombocytopenic Zika virus infection: don't miss it! (Letter) Asian Pac J Trop Med 2016 (published online Mar 23)
Wong LP, Alias H, Aghamohammadi N, et al. Differences in perceived severity of Zika virus infection and dengue fever and its influence on mosquito control practices in Malaysia, a dengue-endemic country. bioRxiv 2016 Jul 1
Xie X, Shan C, Shi PY. Restriction of Zika virus by host innate immunity. Cell Host Microb 2016 (published online May 11)
Xu M, Lee EM, Wen Z, et al. Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen. Nat Med 2016 (published online Aug 29)
Yakob L, Kucharski A, Hue S, et al. Low risk of a sexually-transmitted Zika virus outbreak. (Commentary) Lancet Infect Dis 2016 Oct;(16)10:1100-2
Yin Y, Xu Y, Su L, et al. Epidemiologic investigation of a family cluster of imported ZIKV cases in Guangdong, China: probable human-to-human transmission. Emerg Microb Infect 2016 (published online Sep 7)
Yockey LJ, Varela L, Rakib T, et al. Vaginal exposure to Zika virus during pregnancy leads to fetal brain infection. Cell 2016 Aug 25;166(5):1247-56.e4
Yun SI, Song BH, Frank JC, et al.
Complete genome sequences of three historically important, spatiotemporally distinct, and genetically divergent strains of Zika virus: MR-766, P6-740, and PRVABC-59. Genome Announc 2016 Jul/Aug;4(4):e00800-16
Zhang F, Hammack C, Ogden S, et al.
Molecular signatures associated with ZIKV exposure in human cortical neural progenitors. bioRxiv 2016 Aug 23
Zhang FC, Li XF, Deng YQ, et al.
Excretion of infectious Zika virus in urine. (Letter) Lancet Infect Dis 2016 (published online May 12)
Zhang Y, Chen W, Wong G, et al. Highly diversified Zika viruses imported to China, 2016. Protein Cell 2016 (published online May 21)
Zhao H, Fernandez E, Dowd KA, et al. Structural basis of Zika virus-specific antibody protection. Cell 2016 (published online Jul 27)
Zhu Z, Chan JFW, Tee KM, et al. Comparative genomic analysis of pre-epidemic and epidemic Zika virus strains for virological factors potentially associated with the rapidly expanding epidemic. Emerg Microbes Infect 2016 (published online Mar 16)
Zinszer K, Morrison K, Brownstein JS, et al. Reconstruction of Zika virus introduction in Brazil. Emerg Infect Dis 2016 (published online Sep 12)
Zmurko J, Marques RE, Schols D, et al. The viral polymerase inhibitor 7-deaza-2'-C-methyladenosine is a potent inhibitor of in vitro Zika virus replication and delays disease progression in a robust mouse infection model. PLoS Negl Trop Dis 2016 May 10;10(5):e0004695
Zumla A, Goodfellow I, Kasolo F, Ntoumi F, et al. Zika virus outbreak and the case for building effective and sustainable rapid diagnostics laboratory capacity globally. Int J Infect Dis 2016  (published online Mar 4)

2015

Brown C. Zika virus outbreaks in Asia and South America. CMAJ 2015 Dec 22. pii:cmaj.109-5212
Buathong R, Hermann L, Thaisomboonsuk B, et al. Detection of Zika virus infection in Thailand, 2012-2014. Am J Trop Med Hyg 2015 Aug;93(2):380-3. Epub 2015 Jun 22
Derraik JG, Slaney D. Notes on Zika virus – an emerging pathogen now present in the South Pacific. Aust N Z J Public Health 2015 Feb;39(1):5-7. Epub 2015 Jan 5
Diagne CT, Diallo D, Faye O, et al. Potential of selected Senegalese Aedes spp. mosquitoes (Diptera: Culicidae) to transmit Zika virus. BMC Infect Dis 2015 Nov 2;15:492
Dyer O. Zika virus spreads across Americas as concerns mount over birth defects. BMJ 2015 Dec 23;351:h6983
Gatherer D, Kohl A. Zika virus: a previously slow pandemic spreads rapidly through the Americas. J Gen Virol 2015 Dec 18 [Epub ahead of print]
Gautret P, Simon F. Dengue, chikungunya and Zika and mass gatherings: what happened in Brazil, 2014. Travel Med Infect Dis. 2015 Dec 24. pii:S1477-8939(15)00205-7
Hamel R, Dejarnac O, Wichit S, et al. Biology of Zika virus infection in human skin cells. J Virol 2015 Sep;89(17):8880-96. Epub 2015 Jun 17
Kelser EA. Meet dengue's cousin, Zika. Microbes Infect 2015 Dec 17. pii: S1286-4579(15)00259-2. [Epub ahead of print]
Leung GH, Baird RW, Druce J, et al. Zika virus infection in Australia following a monkey bite in Indonesia. Southeast Asian J Trop Med Public Health 2015 May;46(3):460-4
Marano G, Pupella S, Vaglio S, et al. Zika virus and the never-ending story of emerging pathogens and transfusion medicine. Blood Transfus 2015 Nov 5:1-6. [Epub ahead of print]
Marcondes CB, Ximenes MF. Zika virus in Brazil and the danger of infestation by Aedes (Stegomyia) mosquitoes. Rev Soc Bras Med Trop 2015 Dec 22. pii:S0037-86822015005003102
Martinez-Pulgarin DF, Acevedo-Mendoza WF, Cardona-Ospina JA, et al. A bibliometric analysis of global Zika research. Travel Med Infect Dis 2015 Jul 29. pii: S1477-8939(15)00120-9. [Epub ahead of print]
Musso D, Cao-Lormeau VM, Gubler DJ. Zika virus: following the path of dengue and chikungunya? Lancet 2015 Jul 18;386(9990):243-4
Musso D, Roche C, Nhan TX, et al. Detection of Zika virus in saliva. J Clin Virol 2015 Jul;68:53-5. Epub 2015 Apr 29
Musso D, Roche C, Robin E, et al. Potential sexual transmission of Zika virus. Emerg Infect Dis 2015 Feb;21(3):359-61
Patino-Barbosa AM, Medina I, Gil-Restrepo AF, et al. Zika: another sexually transmitted infection? Sex Transm Infect 2015 Aug;91(5):359. Epub 2015 Jun 25
Porse CC, Kramer V, Yoshimizu MH, et al. Public health response to Aedes aegypti and Ae. albopictus mosquitoes invading California, USA. Emerg Infect Dis 2015 Oct;21(10):1827-9
Rodriguez-Morales AJ. Zika: the new arbovirus threat for Latin America. J Infect Dev Ctries 2015 Jul 4;9(6):684-5
Sabogal-Roman JA, Murillo-Garcia DR, Yepes-Echeverri MC, et al. Healthcare students and workers' knowledge about transmission, epidemiology and symptoms of Zika fever in four cities of Colombia. Travel Med Infect Dis. 2015 Dec 23. pii:S1477-8939(15)00204-5
Salvador FS, Fujita DM. Entry routes for Zika virus in Brazil after 2014 world cup: new possibilities. Travel Med Infect Dis 2015 Nov 14. pii:S1477-8939(15)00173-8. [Epub ahead of print]
Summers DJ, Acosta RW, Acosta AM. Zika Virus in an American recreational traveler. J Travel Med 2015 Sep-Oct;22(5):338-40. Epub 2015 May 21
Tappe D, Perez-Giron JV, Zammarchi L, et al. Cytokine kinetics of Zika virus-infected patients from acute to reconvalescent phase. Med Microbiol Immunol 2015 Dec 24. [Epub ahead of print]
Tognarelli J, Ulloa S, Villagra E, et al. A report on the outbreak of Zika virus on Easter Island, South Pacific, 2014. Arch Virol 2015 Nov 26. [Epub ahead of print]
Zammarchi L, Stella G, Mantella A, et al. Zika virus infections imported to Italy: Clinical, immunological and virological findings, and public health implications. J Clin Virol 2015 Feb;63:32-5. Epub 2014 Dec 12
Zammarchi L, Tappe D, Fortuna C, et al. Zika virus infection in a traveller returning to Europe from Brazil, March 2015. Euro Surveill 2015 Jun 11;20(23):pii=21153
Zanluca C, de Melo VCA, Mosimann ALP, et al. First report of autochthonous transmission of Zika virus in Brazil. Memorias do Instituto Oswaldo Cruz 2015 Jun;110(4):569-72

2014

Althouse BM, Hanley KA, Diallo M, et al. Impact of climate and mosquito vector abundance on sylvatic arbovirus circulation dynamics in Senegal. Am J Trop Med Hyg 2015 Jan;92(1):88-97. Epub 2014 Nov 17
Berthet N, Nakoune E, Kamgang B, et al. Molecular characterization of three Zika flaviviruses obtained from sylvatic mosquitoes in the Central African Republic. Vector Borne Zoonotic Dis 2014 Dec;14(12):862-5
Besnard M, Lastere S, Teissier A, et al. Evidence of perinatal transmission of Zika virus, French Polynesia, December 2013 and February 2014. Euro Surveill 2014;19(13):pii=20751
Diallo D, Sall AA, Diagne CT, et al. Zika virus emergence in mosquitoes in southeastern Senegal, 2011. PLoS One 2014;9(10):e109442
Faye O, Freire CCM, Iamarino A, et al. Molecular evolution of Zika virus during its emergence in the 20th century. PLoS Negl Trop Dis 2014;8(1):e2636
Fonseca K, Meatherall B, Zarra D, et al. First case of Zika virus infection in a returning Canadian traveler. Am J Trop Med Hyg 2014 Nov;91(5):1035-8. Epub 2014 Oct 6
Grard G, Caron M, Mombo IM, et al. Zika virus in Gabon (Central Africa) – 2007: a new threat from Aedes albopictus? PLoS Negl Trop Dis 2014 Feb 6;8(2):e2681
Healy K, Hamilton G, Crepeau T, et al. Integrating the public in mosquito management: active education by community peers can lead to significant reduction in peridomestic container mosquito habitats. PLoS One 2014;9(9): e108504
Ioos S, Mallet HP, Leparc Goffart I, et al. Current Zika virus epidemiology and recent epidemics. Med Mal Infect 2014 Jul;44(7):302-7. Epub 2014 Jul 4
Ledermann JP, Guillaumot L, Yug L, et al. Aedes hensilli as a potential vector of chikungunya and Zika viruses. PLoS Negl Trop Dis 2014;8(10):e3188
Musso D, Nhan T, Robin E, et al. Potential for Zika virus transmission through blood transfusion demonstrated during an outbreak in French Polynesia, November 2013 to February 2014 . Euro Surveill 2014;19(14):pii=20761
Musso D, Nilles EJ, Cao-Lormeau VM. Rapid spread of emerging Zika virus in the Pacific area. Clin Microbiol Infect 2014;20(10):O595-6
Oehler E, Watrin L, Larre P, et al. Zika virus infection complicated by Guillain-Barre syndrome – case report, French Polynesia, December 2013. Euro Surveill 2014;19(9):pii=20720
Roth A, Mercier A, Lepers C, et al. Concurrent outbreaks of dengue, chikungunya and Zika virus infections – an unprecedented epidemic wave of mosquito-borne viruses in the Pacific 2012–2014. Euro Surveill 2014;19(41):pii=20929
Tappe D, Rissland J, Gabriel M, et al. First case of laboratory-confirmed Zika virus infection imported into Europe, November 2013. Euro Surveill 2014;19(4):pii=20685

 

Varjak M, Donald CL, Mottram TJ, et al. Characterization of the Zika virus induced small RNA response in Aedes aegypti cells. PLoS Negl Trop Dis 2017 Oct 17;11(10):e0006010

CDC

Zika and animals (Jun 29, 2017)

Recent Literature

Acosta-Reyes J, Navarro E, Herrera MJ, et al. Severe neurologic disorders in 2 fetuses with Zika virus infection, Colombia. Emerg Infect Dis 2017 (published online Mar 15)

Aleman TS, Ventura CV, Cavalcanti MM, et al. Quantitative assessment of microstructural changes of the retina in infants with congenital Zika syndrome. JAMA Opthalmol 2017 (published online Sep 7)

Atkinson B, Thorburn F, Petridou C, et al. Presence and persistence of Zika virus RNA in semen, United Kingdom, 2016. Emerg Infect Dis 2016 (published online Dec 20)

Bhatnagar J, Rabeneck DB, Martines RB, et al. Zika virus RNA replication and persistence in brain and placental tissue. Emerg Infect Dis 2016 (published online Dec 13)

Boggild AK, Geduld J, Libman M, et al. Surveillance report of Zika virus among Canadian travelers returning from the Americas. CMAJ 2017 Mar 6;189(9):E334-40

Brasil P, Pereira JP Jr, Moreira ME, et al. Zika virus infection in pregnant women in Rio de Janeiro. N Engl J Med 2016 (published online Dec 13)

Brito CAA, Azevedo F, Cordero MT, et al. Central and peripheral nervous system involvement caused by Zika and chikungunya coinfection. PLoS Negl Trop Dis 2017 (published online Jul 13)

Cao B, Parnell LA, Diamond MS, et al. Inhibition of autophagy limits vertical transmission of Zika virus in pregnant mice. J Exp Med 2017 (published online Jul 10)

Castanha PMS, Nascimento EJM, Cynthia B, et al. Dengue virus (DENV)-specific antibodies enhance Brazilian Zika virus (ZIKV) infection. J Infect Dis 2016 (published online Dec 29)

Cavalcanti MG, Cabral-Castro MJ, Goncalves JLS, et al. Zika virus shedding in human milk during lactation: an unlikely source of infection? Int J Infect Dis 2017 (published online Feb 7)

Chammard TB, Schepers K, Breurec S, et al. Severe thrombocytopenia after Zika virus infection, Guadeloupe, 2016. Emerg Infect Dis 2016 (published online Dec 20)

Chevalier MS, Biggerstaff BJ, Basavaraju SV, et al. Use of blood donor screening data to estimate Zika virus incidence, Puerto Rico, April-August 2016. Emerg Infect Dis 2017 (published online Mar 6)

Cragan JD, Mai CT, Petersen EE, et al. Baseline prevalence of birth defects associated with congenital Zika virus infection Massachusetts, North Carolina, and Atlanta, Georgia, 2013-2014. MMWR 2017 Mar 3;66(8):219-22

D'Angelo DV, von Essen BS, Lamias MJ, et al. Measures taken to prevent Zika virus infection during pregnancy — Puerto Rico, 2016. MMWR 2017 Jun 9;66(22):574-8

de Oliveira WK, Henriques CM, Coelho G, et al. Zika virus and associated neurologic disorders in Brazil. (Letter) N Engl J Med 2017 (published online Mar 29)

de Olveira WK, de Franca GVA, Carmo EH, et al. Infection-related microcephaly after the 2015 and 2016 Zika virus outbreaks in Brazil: a surveillance-based analysis. Lancet 2017 (published online Jun 21)

Fernandez MP, Saad EP,  Martinez MO, et al. Ocular histopathologic features of congenital Zika syndrome. JAMA Ophthalmol 2017 (published online Sep 21)

Flamand C, Fritzell C, Matheus S, et al. The proportion of asymptomatic infections and spectrum of disease among pregnant women infected by Zika virus: systematic monitoring in French Guiana, 2016. Euro Surveill 2017 Nov 2;22(44):pii=17-00102

GAO (US Government Accountability Office). Emerging infectious diseases: actions needed to address the challenges of responding to Zika virus disease outbreaks. GAO-17-445. May 23, 2017

Gaudinski MR, Houser KV, Morabito KM, et al. Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials. Lancet 2017 (published online Dec 4)

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Grubaugh ND, Ladner JT, Kraemer MUG, et al. Genomic epidemiology reveals multiple introductions of Zika virus into the United States. (Letter) Nature 2017 (published online May 24)

Hall NB, Broussard K, Evert N, et al. Zika virus-associated neonatal birth defects surveillance — Texas, January 2016-July 2017. (Notes from the field) MMWR 2017 Aug 11;66(31):835-6

Halstead SB. Achieving safe, effective, and durable Zika virus vaccines: lessons from dengue. Lancet 2017 (published online Jul 12)

Hart CE, Roundy CM, Azar SR, et al. Zika virus vector competency of mosquitoes, Gulf Coast, United States. (Letter) Emerg Infect Dis 2016 (published online Dec 22)

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