Study: Antibiotics for bacterial vaginosis don't cut preterm birth risk

The results of a large randomized, controlled trial in France suggest that early antibiotic treatment for bacterial vaginosis does not reduce the risk for late miscarriage or very preterm birth in women who have low-risk pregnancies.

The study of more than 84,000 pregnant women at 40 French hospitals, published in The Lancet, found that the rate of late miscarriage and spontaneous very preterm birth was nearly equal in women with low-risk pregnancies who were randomly assigned to receive clindamycin or a placebo before 15 weeks' gestation. In addition, a sub-trial in women with high-risk pregnancies found no significant difference in rates of late miscarriage or very preterm delivery between women who received either a single course or