Antimicrobial Stewardship

Bibliography

Last updated Jul 22, 2016.

Antimicrobial Resistance

2016
2015
2014
2013
2012
2011
2010

2016

Adams DJ, Eberly MD, Goudie A, et al. Rising vancomycin-resistant Enterococcus infection in hospitalized children in the United States. Hosp Pediatr 2016 (published online Jun 1)

Akova M. Epidemiology of antimicrobial resistance in bloodstream infections. Virulence 2016 Apr 2;7(3):252-66

Bairy LK, Nayak V, A A, et al. Advances in pharmacovigilance initiatives surrounding antimicrobial resistance — Indian perspective. Expert Opin Drug Saf 2016 (published online May 13)

Bassetti M, Welte T, Wunderink RG. Treatment of gram-negative pneumonia in the critical care setting: is the beta-lactam antibiotic backbone broken beyond repair? Crit Care 2 2016 Jan 29;20:19

Batina NG, Crnich CJ, Anderson DF, et al. Models to predict prevalence and transition dynamics of methicillin-resistant Staphylococcus aureus in community nursing homes. Am J Infect Control 2016 May 1;44(5):507-14

Bryce A, Hay AD, Lane IF, et al. Global prevalence of antibiotic resistance in paediatric urinary tract infections caused by Escherichia coli and association with routine use of antibiotics in primary care: systematic review and meta-analysis. BMJ 2016 (published online Mar 15)

Cerceo E, Deitelzweig SB, Sherman BM, et al. Multidrug-resistant gram-negative bacterial infections in the hospital setting: overview, implications for clinical practice, and emerging treatment options. Microb Drug Resist 2016 (published online Feb 11)

Clock SA, Ferng YH, Tabibi S, et al. Colonization with antimicrobial-resistant gram-negative bacilli at neonatal Intensive Care Unit discharge. J Pediatric Infect Dis Soc 2016 (published online Mar 28)

Goodman KE, Simner PJ, Tamma PD, et al. Infection control implications of heterogeneous resistance mechanisms in carbapenem-resistant Enterobacteriaceae (CRE). Expert Rev Anti Infect Ther 2016 Jan;14(1):95-108

Friedman ND, Temkin E, Carmeli Y. The negative impact of antibiotic resistance. Clin Microbiol Infect 2016 May;22(5):416-22

Guillard T, Pons S, Roux D, et al. Antibiotic resistance and virulence: understanding the link and its consequences for prophylaxis and therapy. Bioessays 2016 Jul;38(7):682-93

Hefzy EM, Hassuna NA. Fluoroquinolone-resistant sequence type 131 subgroups O25b and O16 among extraintestinal Escherichia coli Isolates from community-acquired urinary tract infections. Microb Drug Resist 2016 (published online May 23)

Holmes AH, Moore LS, Sundsfjord A, et al. Understanding the mechanisms and drivers of antimicrobial resistance. Lancet 2016 Jan 9;387(10014):176-87

Holubar M, Meng l, Deresinski S. Bacteremia due to methicillin-resistant Staphylococcus aureus: new therapeutic approaches. Infect Dis Clin North Am 2016 Jun;30(2):491-507

Hwang AY, Gums JG. The emergence and evolution of antimicrobial resistance: impact on a global scale. Bioorg Med Chem 2016 (published online Apr 13)

Karam G, Chastre J, Wilcox MH, et al. Antibiotic strategies in the era of multidrug resistance. Crit Care 2016 Jun 22;20(1):136

Karlowsky JA, Biedenbach DJ, Bouchillon SK, et al. In vitro activity of ceftaroline against bacterial pathogens isolated from skin and soft tissue infections in Europe, Russia and Turkey in 2012: results from the Assessing Worldwide Antimicrobial Resistance Evaluation (AWARE) surveillance programme. J Antimicrob Chemother 2016 Jan;71(1):162-9

Leski TA, Taitt CR, Bangura U, et al. High prevalence of multidrug resistant Enterobacteriaceae isolated from outpatient urine samples but not the hospital environment in Bo, Sierra Leone. BMC Infect Dis 2016 Apr 18;16(1):167

Li YL, Tewari D, Yealy CC, et al. Surveillance for travel and domestically acquired multidrug-resistant human Shigella infections — Pennsylvania, 2006-2014. Health Secur 2016 May-Jun;14(3):143-51

MacVane SH. Antimicrobial resistance in the intensive care unit: a focus on gram-negative bacterial infections. J Intensive Care Med 2016 (published online Jan 15)

McKinnell JA, Kunz DF, Moser SA, et al. Patient-level analysis of incident vancomycin-resistant enterococci colonization and antibiotic days of therapy. Epidemiol Infect 2016 Jun;144(8):1748-55

Meletis G. Carbapenem resistance: overview of the problem and future perspectives. Ther Adv Infect Dis 2016 Feb;3(1):15-21

Miller WR, Murray BE, Rice LB, et al. Vancomycin-resistant Enterococci: therapeutic challenges in the 21st century. Infect Dis Clin North Am 2016 Jun;30(2):415-39

Mills JP, Talati NJ, Alby K, et al. The epidemiology of carbapenem-resistant Klebsiella pneumoniae colonization and infection among long-term acute care hospital residents. Infect Control Hosp Epidemiol 2016 Jan;37(1):55-60

Mohammed Y, Gadzama GB, Zailani SB, et al. Characterization of extended-spectrum beta-lactamase from Escherichia coli and Klebsiella species from north eastern Nigeria. J Clin Diagn Res 2016 Feb;10(2):DC07-10

Morgenstern M, Erichsen C, Hackl S, et al. Antibiotic resistance of commensal Staphylococcus aureus and coagulase-negative Staphylococci in an international cohort of surgeons: a prospective point-prevalence study. PLoS One 2016 Feb 3;11(2):e0148437

Moxon CA, Paulus S. Beta-lactamases in Enterobacteriaceae infections in children. J Infect 2016 Jul 5;72(Suppl):S41-9

Ndir A, Diop A, Faye PM, et al. Epidemiology and burden of bloodstream infections caused by extended-spectrum beta-lactamase producing Enterobacteriaceae in a pediatric hospital in Senegal. PLoS One 2016 Feb 11;11(2):e0143729

Patel SJ, Green N, Clock SA, et al. Gram-negative bacilli in infants hospitalized in the neonatal intensive care unit. J Pediatr Infect Dis Soc 2016 (published online Jun 14)

Schwarz S, Johnson AP. Transferable resistance to colistin: a new but old threat. J Antimicrob Chemother 2016 (published online Jun 24)

Spencer JR, Milburn EK, Chukwuma U. Correlation between antimicrobial resistance in Escherichia coli infections in hospitalized patients and rates of inpatient prescriptions for selected antimicrobial agents, Department of Defense hospitals, 2010-2014. MSMR 2016 Mar;23(3):6-10

Suwantarat N, Carroll KC. Epidemiology and molecular characterization of multidrug-resistant Gram-negative bacteria in Southeast Asia. Antimicrob Resist Infect Control 2016 May 4;5:15

Tatarelli P, Mikulska M. Multidrug-resistant bacteria in hematology patients: emerging threats. Future Microbiol 2016 Jun;11:767-80

Thung I, Aramin H, Vavinskaya V, et al. Review article: the global emergence of Helicobacter pylori antibiotic resistance. Aliment Pharmacol Ther 2016 Feb;43(4):514-33

Watkins RR, Bonomo RA. Overview: global and local impact of antibiotic resistance. Infect Dis Clin North Am 2016 Jun;30(2):313-22

Weiner LM, Fridkin SK, Aponte-Torres Z, et al. Vital signs: preventing antibiotic-resistant infections in hospitals — United States, 2014. MMWR 2016 Mar 11;65(9):235-41

Zerr DM, Miles-Jay A, Kronman MP, et al. Previous antibiotic exposure increases risk of infection with extended spectrum beta lactamase- and AmpC-producing Escherichia coli and Klebsiella pneumoniae in pediatric patients. Antimicrob Agents Chemother 2016 May;60(7):4237-43

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2015

Abat C, Desboves G, Olaitan AO, et al. Increasing burden of urinary tract infections due to intrinsic colistin-resistant bacteria in hospitals in Marseille, France. Int J Antimicrob Agents 2015 Feb;45(2):144-50

Abbott IJ, Peleg AY. Stenotrophomonas, Achromobacter, and nonmelioid Burkholderia species: antimicrobial resistance and therapeutic strategies. Semin Respir Crit Care Med 2015 Feb;36(1):99-110

Ahmed I, Sajed M, Sultan A, et al. The erratic antibiotic susceptibility patterns of bacterial pathogens causing urinary tract infections. EXCLI J 2015 Aug 4;14:916-25

Antonanzas F, Lozano C, Torres C. Economic features of antibiotic resistance: the case of methicillin-resistant Staphylococcus aureus. Pharmacoeconomics 2015 Apr;33(4):285-325

Arnaud I, Maugat S, Jarlier V, et al. Ongoing increasing temporal and geographical trends of the incidence of extended-spectrum beta-lactamase-producing Enterobacteriaceae infections in France, 2009 to 2013. Euro Surveill 2015 Sep;20(36):pii=30014

Asbell PA, Sanfilippo CM, Pillar CM, et al. Antibiotic resistance among ocular pathogens in the United States: five-year results from the antibiotic resistance monitoring in ocular microorganisms (ARMOR) surveillance study. JAMA Ophthalmol 2015 Dec;133(12):1445-54

Barber KE, King ST, Stover KR, et al. Therapeutic options for vancomycin-resistant enterococcal bacteremia. Expert Rev Anti Infect Ther 2015 Mar;13(3):363-77

Barfod TS, Wibroe EA, Brauner JV, et al. Changes in antimicrobial susceptibility patterns of Klebsiella pneumoniae, Escherichia coli and Staphylococcus aureus over the past decade. Dan Med J 2015 Oct;62(10):A5145

Barlam TF, Gupta K. Antibiotic resistance spreads internationally across borders. J Law Med Ethics 2015 Summer;43(Suppl 3):12-6

Beever L, Bond R, Graham PA, et al. Increasing antimicrobial resistance in clinical isolates of Staphylococcus intermedius group bacteria and emergence of MRSP in the UK. Vet Rec 2015 Feb 14;176(7):172

Bialvaei AZ, Samadi Kafil H. Colistin, mechanisms and prevalence of resistance. Curr Med Res Opin 2015 Apr;31(4):707-21

Bielicki JA, Lundin R, Sharland M, et al. Antibiotic resistance prevalence in routine bloodstream isolates from children's hospitals varies substantially from adult surveillance data in Europe. Pediatr Infect Dis J 2015 Jul;34(7):734-41

Blair JM, Webber MA, Baylay AJ, et al. Molecular mechanisms of antibiotic resistance. Nat Rev Microbiol 2015 Jan;13(1):42-51

Bowen A, Hurd J, Hoover C, et al. Importation and domestic transmission of Shigella sonnei resistant to ciprofloxacin — United States, May 2014-February 2015. MMWR 2015 Apr 3;64(12):318-20

Boyle DP, Zembower TR. Epidemiology and management of emerging drug-resistant gram-negative bacteria: extended-spectrum beta-lactamases and beyond. Urol Clin North Am 2015 Nov;42(4):493-505

Buono SA, Watson TD, Borenstein LA, et al. Stemming the tide of drug-resistant Neisseria gonorrhoeae: the need for an individualized approach to treatment. J Antimicrob Chemother 2015 Feb;70(2):374-81

Cai T, Nesi G, Mazzoli S, et al. Asymptomatic bacteriuria treatment is associated with a higher prevalence of antibiotic resistant strains in women with urinary tract infections. Clin Infect Dis 2015 Dec 1;61(11):1655-61

Calbo E, Garau J. The changing epidemiology of hospital outbreaks due to ESBL-producing Klebsiella pneumoniae: the CTX-M-15 type consolidation. Future Microbiol 2015 Jun;10(6):1063-75

Chang VS, Dhaliwal DK, Raju L, et al. Antibiotic resistance in the treatment of Staphylococcus aureus keratitis: a 20-Year Review. Cornea 2015 Jun;34(6):698-703

Ciorba V, Odone A, Veronesi L, et al. Antibiotic resistance as a major public health concern: epidemiology and economic impact. Ann Ig 2015 May-Jun;27(3):562-79

Cleveland AA, Harrison LH, Farley MM, et al. Declining incidence of candidemia and the shifting epidemiology of Candida resistance in two US metropolitan areas, 2008-2013: results from population-based surveillance. PLoS One 2015 Mar 30;10(3):e0120452

Cole MJ, Spiteri G, Jacobsson S, et al. Is the tide turning again for cephalosporin resistance in Neisseria gonorrhoeae in Europe? Results from the 2013 European surveillance. BMC Infect Dis 2015 Aug 11;15:321,015-1013-x

De Santis V, Gresoiu M, Corona A, et al. Bacteraemia incidence, causative organisms and resistance patterns, antibiotic strategies and outcomes in a single university hospital ICU: continuing improvement between 2000 and 2013. J Antimicrob Chemother 2015 Jan;70(1):273-8

Doi Y, Paterson DL. Carbapenemase-producing Enterobacteriaceae. Semin Respir Crit Care Med 2015 Feb;36(1):74-84

Drusano GL, Louie A, MacGowan A, et al. Suppression of emergence of resistance in pathogenic bacteria: Keeping our powder dry, part 1. Antimicrob Agents Chemother 2015 Dec 28;60(3):1183-93

Drusano GL, Hope W, MacGowan A, et al. Suppression of emergence of resistance in pathogenic bacteria: Keeping our powder dry, part 2. Antimicrob Agents Chemother 2015 Dec 28;60(3):1194-201

Dryden M, Andrasevic AT, Bassetti M, et al. Managing skin and soft-tissue infection and nosocomial pneumonia caused by MRSA: a 2014 follow-up survey. Int J Antimicrob Agents 2015 Apr 24;45 Suppl 1:S1-14

Fanella S, Embree J. Pediatric Staphylococcus aureus Infections: impact of methicillin resistance at a Canadian center. South Med J 2015 May;108(5):254-7

Ferjani S, Saidani M, Amine FS, et al. A comparative study of antimicrobial resistance rates and phylogenetic groups of community-acquired versus hospital-acquired invasive Escherichia coli. Med Mal Infect 2015 Apr;45(4):133-8

Ferri M, Ranucci E, Romagnoli P, et al. Antimicrobial resistance: a global emerging threat to public health systems. Crit Rev Food Sci Nutr 2015 Oct 13:0

Fridkin SK, Cleveland AA, See I, et al. Emerging Infections Program as surveillance for antimicrobial drug resistance. Emerg Infect Dis 2015 Sep;21(9):1578-81

Garner MJ, Carson C, Lingohr EJ, et al. An assessment of antimicrobial resistant disease threats in Canada. PLoS One 2015 Apr 23;10(4):e0125155

Gentry CA, Williams RJ 2nd. Trends in susceptibility rates and extended-spectrum beta-lactamase production of Klebsiella pneumoniae in bloodstream infections across the United States Veterans Affairs Healthcare System. Microb Drug Resist 2015 Dec;21(6):590-9

George CE, Norman G, Ramana GV, et al. Treatment of uncomplicated symptomatic urinary tract infections: resistance patterns and misuse of antibiotics. J Family Med Prim Care 2015 Jul-Sep;4(3):416-21

Gharbi M, Moore LS, Gilchrist M, et al. Forecasting carbapenem resistance from antimicrobial consumption surveillance: lessons learnt from an OXA-48-producing Klebsiella pneumoniae outbreak in a West London renal unit. Int J Antimicrob Agents 2015 Aug;46(2):150-6

Gibble AM, Gross AE, Huang AM. Examining the clinical effectiveness of non-carbapenem beta-lactams for the treatment of extended-spectrum beta-lactamase-producing Enterobacteriaceae. Antibiotics (Basel) 2015 Dec 15;4(4):653-66

Goldsmith CE, Hara Y, Sato T, et al. Comparison of antibiotic susceptibility in viridans group streptococci in low and high antibiotic-prescribing General Practices. J Clin Pharm Ther 2015 Apr;40(2):204-7

Guidry CA, Davies SW, Metzger R, et al. Whence resistance? Surg Infect (Larchmt) 2015 Dec;16(6):716-20

Guiral E, Saez-Lopez E, Bosch J, et al. Antimicrobial resistance and virulence characterization among Escherichia coli clinical isolates causing severe obstetric infections in pregnant women. J Clin Microbiol 2015 May;53(5):1745-7

Harris P, Paterson D, Rogers B. Facing the challenge of multidrug-resistant gram-negative bacilli in Australia. Med J Aust 2015 Mar 16;202(5):243-7

Heil EL, Lowery AV, Thom KA, et al. Treatment of multidrug-resistant Pseudomonas aeruginosa using extended infusion antimicrobial regimens. Pharmacotherapy 2015 Jan;35(1):54-8

Holmes NE, Tong SY, Davis JS, et al. Treatment of methicillin-resistant Staphylococcus aureus: vancomycin and beyond. Semin Respir Crit Care Med 2015 Feb;36(1):17-30

Holt KE, Wertheim H, Zadoks RN, et al. Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health. Proc Natl Acad Sci 2015 Jul 7;112(27):E3574-81

Ironmonger D, Edeghere O, Bains A, et al. Surveillance of antibiotic susceptibility of urinary tract pathogens for a population of 5.6 million over 4 years. J Antimicrob Chemother 2015 Jun;70(6):1744-50

Jean SS, Lee WS, Lam C, et al. Carbapenemase-producing Gram-negative bacteria: current epidemics, antimicrobial susceptibility and treatment options. Future Microbiol 2015 Mar;10(3):407-25

Johnson AP. Surveillance of antibiotic resistance. Philos Trans R Soc Lond B Biol Sci 2015 Jun 5;370(1670):20140080

Joseph NM, Bhanupriya B, Shewade DG, et al. Relationship between antimicrobial consumption and the incidence of antimicrobial resistance in Escherichia coli and Klebsiella pneumoniae isolates. J Clin Diagn Res 2015 Feb;9(2):DC08-12

Karlowsky JA, Biedenbach DJ, Bouchillon SK, et al. In vitro activity of ceftaroline against bacterial pathogens isolated from skin and soft tissue infections in Europe, Russia and Turkey in 2012: results from the Assessing Worldwide Antimicrobial Resistance Evaluation (AWARE) surveillance programme. J Antimicrob Chemother 2015 Jan;71(1):162-9

Lai CC, Chu CC, Cheng A, et al. Correlation between antimicrobial consumption and incidence of health-care-associated infections due to methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci at a university hospital in Taiwan from 2000 to 2010. J Microbiol Immunol Infect 2015 Aug;48(4):431-6

Lesho EP, Clifford RJ, Chukwuma U, et al. Carbapenem-resistant Enterobacteriaceae and the correlation between carbapenem and fluoroquinolone usage and resistance in the US military health system. Diagn Microbiol Infect Dis 2015 Feb;81(2):119-25

Lindsay JA. Transmission of antimicrobial resistance in resource-poor healthcare. Trends Microbiol 2015 Feb;23(2):69-70

Lob SH, Kazmierczak KM, Badal RE, et al. Trends in susceptibility of Escherichia coli from intra-abdominal infections to ertapenem and comparators in the United States according to data from the SMART program, 2009 to 2013. Antimicrob Agents Chemother 2015 Jun;59(6):3606-10

Logan LK, Renschler JP, Gandra S, et al. Carbapenem-resistant Enterobacteriaceae in children, United States, 1999-2012. Emerg Infect Dis 2015 Nov;21(11):2014-21

Manenzhe RI, Zar HJ, Nicol MP, et al. The spread of carbapenemase-producing bacteria in Africa: a systematic review. J Antimicrob Chemother 2015 Jan;70(1):23-40

Mills JP, Talati NJ, Alby K, et al. The epidemiology of carbapenem-resistant Klebsiella pneumoniae colonization and infection among long-term acute care hospital residents. Infect Control Hosp Epidemiol 2015 (published online Oct 12)

Ny P, Nieberg P, Wong-Beringer A. Impact of carbapenem resistance on epidemiology and outcomes of nonbacteremic Klebsiella pneumoniae infections. Am J Infect Control 2015 Oct 1;43(10):1076-80

Oliveira MC, Oliveira CR, Goncalves KV, et al. Enterobacteriaceae resistant to third generation cephalosporins upon hospital admission: risk factors and clinical outcomes. Braz J Infect Dis 2015 May-Jun;19(3):239-45

Pannaraj PS, Bard JD, Cerini C, et al. Pediatric carbapenem-resistant Enterobacteriaceae in Los Angeles, California, a high-prevalence region in the United States. Pediatr Infect Dis J 2015 Jan;34(1):11-6

Prestinaci F, Pezzotti P, Pantosti A. Antimicrobial resistance: a global multifaceted phenomenon. Pathog Glob Health 2015 Oct;109(7):309-18

Roca I, Akova M, Baquero F, et al. The global threat of antimicrobial resistance: science for intervention. New Microbes New Infect 2015 Apr 16;6:22-9

Sabtu N, Enoch DA, Brown NM. Antibiotic resistance: what, why, where, when and how? Br Med Bull 2015;116:105-13

Slayton RB, Toth D, Lee BY, et al. Vital signs: estimated effects of a coordinated approach for action to reduce antibiotic-resistant infections in health care facilities — United States. MMWR 2015 Aug 7;64(30):826-31

Spellberg B, Bonomo RA. Combination therapy for extreme rrug-resistant Acinetobacter baumannii: ready for prime time? Crit Care Med 2015 Jun;43(6):1332-4

Spellberg B, Doi Y. The rise of fluoroquinolone-resistant Escherichia coli in the community: scarier than we thought. J Infect Dis 2015 Dec 15;212(12):1853-5

Sutherland CA, Nicolau DP. Susceptibility profile of ceftolozane/tazobactam and other parenteral antimicrobials against Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa from US hospitals. Clin Ther 2015 Jul 1;37(7):1564-71

Tal Jasper R, Coyle JR, Katz DE, et al. The complex epidemiology of extended-spectrum beta-lactamase-producing Enterobacteriaceae. Future Microbiol 2015;10(5):819-39

Tangden T, Giske CG. Global dissemination of extensively drug-resistant carbapenemase-producing Enterobacteriaceae: clinical perspectives on detection, treatment and infection control. J Intern Med 2015 May;277(5):501-12

Teillant A, Gandra S, Barter D, et al.. Potential burden of antibiotic resistance on surgery and cancer chemotherapy antibiotic prophylaxis in the USA: a literature review and modelling study. Lancet Infect Dis 2015 Dec;15(12):1429-37

van Bijnen EM, Paget J, de Lange-de Klerk ES, et al. Antibiotic exposure and other risk factors for antimicrobial resistance in nasal commensal Staphylococcus aureus: an ecological study in 8 European countries. PLoS One 2015 Aug 11;10(8):e0135094

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2014

Abera B, Kibret M, Mulu W. Knowledge and beliefs on antimicrobial resistance among physicians and nurses in hospitals in Amhara Region, Ethiopia. BMC Pharmacol Toxicol 2014 May 19;15:26

Anderson DJ, Moehring RW, Sloane R, et al. Bloodstream infections in community hospitals in the 21st century: a multicenter cohort study. PLoS One 2014 Mar 18;9(3):e91713

Arendrup MC, Perlin DS. Echinocandin resistance: an emerging clinical problem? Curr Opin Infect Dis 2014 Dec;27(6):484-92

Bassetti M, Baguneid M, Bouza E, et al. European perspective and update on the management of complicated skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus after more than 10 years of experience with linezolid. Clin Microbiol Infect 2014 apr;20(Suppl 4):3-18

Bassetti M, Nicolau DP, Calandra T. What's new in antimicrobial use and resistance in critically ill patients? Intensive Care Med 2014 Mar;40(3):422-6

Bebell LM, Muiru AN. Antibiotic use and emerging resistance: how can resource-limited countries turn the tide? Glob Heart 2014 Sep;9(3):347-58

Berezin EN, Solorzano F, Latin America Working Group on Bacterial Resistance. Gram-negative infections in pediatric and neonatal intensive care units of Latin America. J Infect Dev Ctries 2014 Aug 13;8(8):942-53

Chambers HF, Bartlett, JG, Bonomo RA, et al. Antibacterial resistance leadership group: open for business. Clin Infect Dis 2014 Jun;58(11):1571-6

Corbellini S, Caccuri F, Gelmi M, et al. Emergence of carbapenem-resistant Klebsiella pneumoniae strains producing KPC-3 in Brescia Hospital, Italy. New Microbiol 2014 Apr;37(2):177-83

David MZ, Daum RS, Bayer AS, et al. Staphylococcus aureus bacteremia at 5 US academic medical centers, 2008-2011: significant geographic variation in community-onset infections. Clin Infect Dis 2014 Sep 15;59(6):798-807

Enne VI, Personne Y, Grgic L, et al. Aetiology of hospital-acquired pneumonia and trends in antimicrobial resistance. Curr Opin Pulm Med 2014 May;20(3):252-8

Fan NC, Chen HH, Chen CL, et al. Rise of community-onset urinary tract infection caused by extended-spectrum beta-lactamase-producing Escherichia coli in children. J Microbiol Immunol Infect 2014 Oct;47(5):399-405

Farmakiotis D, Tarrand JJ, Kontoyiannis DP. Drug-resistant Candida glabrata infection in cancer patients. Emerg Infect Dis 2014 Nov;20(11):1833-40

Gandra S, Barter DM, Laxminarayan R. Economic burden of antibiotic resistance: how much do we really know? Clin Microbiol Infect 2014 Oct;20(10):973-80

Gandra S, Braykov N, Laxminarayan R. Is methicillin-susceptible Staphylococcus aureus (MSSA) sequence type 398 confined to northern Manhattan? Rising prevalence of erythromycin- and clindamycin-resistant MSSA clinical isolates in the United States. Clin Infect Dis 2014 Jan;58(2):306-7

Gedik H, Simsek F, Kanturk A, et al. Bloodstream infections in patients with hematological malignancies: which is more fatal — cancer or resistant pathogens? Ther Clin Risk Manag 2014 Sep 17;10:743-52

Gudiol C, Carratala J. Antibiotic resistance in cancer patients. Expert Rev Anti Infect Ther 2014 Aug;12(8):1003-16

Haghi-Ashtiani MT, Sadeghian M, Nikmanesh B, et al. Antimicrobial susceptibility trends among Streptococcus pneumoniae over an 11-year period in an Iranian referral children hospital. Iran J Microbiol 2014 Dec;6(6):382-6

Hawser SP, Badal RE, Bouchillon SK, et al. Susceptibility of gram-negative aerobic bacilli from intra-abdominal pathogens to antimicrobial agents collected in the United States during 2011. J Infect 2014 Jan;68(1):71-6

Hughes D. Selection and evolution of resistance to antimicrobial drugs. IUBMB Life 2014 Aug;66(8):521-9

Hull CM, Purdy NJ, Moody SC. Mitigation of human-pathogenic fungi that exhibit resistance to medical agents: can clinical antifungal stewardship help? Future Microbiol 2014;9(3):307-25

Jones RN, Flonta M, Gurler N, et al. Resistance surveillance program report for selected European nations (2011). Diagn Microbiol Infect Dis 2014 Apr;78(4):429-36

Kavanagh KT, Calderon LE, Saman DM, et al. The use of surveillance and preventative measures for methicillin-resistant staphylococcus aureus infections in surgical patients. Antimicrob Resist Infect Control 2014 May 14;3:18

Khumalo J, Saidi B, Mbanga J. Evolution of antimicrobial resistance of Salmonella enteritidis (1972-2005). Onderstepoort J Vet Res 2014 Nov 12;81(1)

Lee CS, Doi Y. Therapy of Infections due to carbapenem-resistant gram-negative pathogens. Infect Chemother 2014 Sep;46(3):149-64

Logan LK, Braykov NP, Weinstein RA, et al. Extended-spectrum beta-lactamase-producing and third-generation cephalosporin-resistant Enterobacteriaceae in children: trends in the United States, 1999-2011. J Pediatric Infect Dis Soc 2014 Dec;3(4):320-8

Logan LK, Meltzer LA, McAuley JB, et al. Extended-spectrum beta-lactamase-producing Enterobacteriaceae infections in children: a two-center case-case-control study of risk factors and outcomes in Chicago, Illinois. J Pediatric Infect Dis Soc 2014 Dec;3(4):312-9

MacVane SH, Tuttle LO, Nicolau DP. Impact of extended-spectrum beta-lactamase-producing organisms on clinical and economic outcomes in patients with urinary tract infection. J Hosp Med 2014 Apr;9(4):232-8

Martin-Loeches I, Diaz E, Valles J. Risks for multidrug-resistant pathogens in the ICU. Curr Opin Crit Care 2014 Oct;20(5):516-24

May L, Klein EY, Rothman RE, et al. Trends in antibiotic resistance in coagulase-negative staphylococci in the United States, 1999 to 2012. Antimicrob Agents Chemother 2014;58(3):1404-9

Moremi N, Mushi MF, Fedelis M, et al. Predominance of multi-resistant gram-negative bacteria colonizing chronic lower limb ulcers (CLLUs) at Bugando Medical Center. BMC Res Notes 2014 Apr 4;7:211

Nathwani D, Eckmann C, Lawson W, et al. Influence of real-world characteristics on outcomes for patients with methicillin-resistant Staphylococcal skin and soft tissue infections: a multi-country medical chart review in Europe. BMC Infect Dis 2014 Sep 2;14:476

Nathwani D, Raman G, Sulham K, et al. Clinical and economic consequences of hospital-acquired resistant and multidrug-resistant Pseudomonas aeruginosa infections: a systematic review and meta-analysis. Antimicrob Resist Infect Control 2014 Oct 20;3(1):32

Nicolini G, Sperotto F, Esposito S. Combating the rise of antibiotic resistance in children. Minerva Pediatr 2014 Feb;66(1):31-9

Ng TM, Teng CB, Lye DC, et al. A multicenter case-case control study for risk factors and outcomes of extensively drug-resistant Acinetobacter baumannii bacteremia. Infect Control Hosp Epidemiol 2014 Jan;35(1):49-55

Norton TD, Skeete F, Dubrovskaya Y, et al. Orthopedic surgical site infections: analysis of causative bacteria and implications for antibiotic stewardship. Am J Orthrop (Belle Mead NJ) 2014 May;43(5):E89-92

Patel DA, Shorr AF, Chastre J, et al. Modeling the economic impact of linezolid versus vancomycin in confirmed nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus. Crit Care 2014 Jul 22;18(4):R157

Rajkumari N, John NV, Mathur P, et al. Antimicrobial resistance in Pseudomonas sp. causing infections in trauma patients: a 6 year experience from a South Asian country. J Glob Infect Dis 2014 Oct;6(4):182-5

Robilotti E, Deresinski S. Carbapenemase-producing Klebsiella pneumoniae. F1000Prime Rep 2014 Sep4;6:80

Shetty V, Trumbull K, Hegde A, et al. Prevalence of community-acquired methicillin-resistant Staphylococcus aureus nasal colonization among children. J Clin Diagn Res 2014 Dec;8(12):DC12-5

Spagnolo AM, Orlando P, Panatto D, et al. Staphylococcus aureus with reduced susceptibility to vancomycin in healthcare settings. J Prev Med Hyg 2014 Dec;55(4):137-44

Spellberg B, Bonomo RA. The deadly impact of extreme drug resistance in Acinetobacter baumannii. Crit Care Med 2014 May;42(5):1289-91

Thacker N, Pereira N, Banavali SD, et al. Alarming prevalence of community-acquired multidrug-resistant organisms colonization in children with cancer and implications for therapy: a prospective study. Indian J Cancer 2014 Oct-Dec;51(4):442-6

Thacker N, Pereira N, Banavali SD, et al. Epidemiology of blood stream infections in pediatric patients at a tertiary care cancer centre. Indian J Cancer 2014 Oct-Dec;51(4):438-41

Tokajian S. New epidemiology of Staphylococcus aureus infections in the Middle East. Clin Microbiol Infect 2014 Jul;20(7):624-8

Tsai MH, Wu TL, Su LH, et al. Carbapenem-resistant-only Pseudomonas aeruginosa infection in patients formerly infected by carbapenem-susceptible strains. Int J Antimicrob Agents 2014 Dec;44(6):541-5

Van TD, Dinh QD, Vu PD, et al. Antibiotic susceptibility and molecular epidemiology of Acinetobacter calcoaceticus-baumannii complex strains isolated from a referral hospital in northern Vietnam. J Glob Antimicrob Resist 2014 Dec;2(4):318-21

Voor In't Hold AF, Severin JA, Lesaffre EM, et al. A systematic review and meta-analyses show that carbapenem use and medical devices are the leading risk factors for carbapenem-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother 2014 May;58(5):2626-37

Wailan AM, Paterson DL. The spread and acquisition of NDM-1: a multifactorial problem. Expert Rev Anti Infect Ther 2014 Jan;12(1):91-115

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2013

Bogan C, et al. The role of antimicrobial stewardship in curbing carbapenem resistance. Future Microbiol 2013 Aug;8(8):979-91

Braykov NP, et al. Trends in resistance to carbapenems and third-generation cephalosporins among clinical isolates of Klebsiella pneumoniae in the United States, 1999-2010. Infect Control Hosp Epidemiol 2013 Mar;34(3):259-68

Casapao AM, et al. Clinical outcomes in patients with heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) bloodstream infection. Antimicrob Agents Chemother 2013 Jun 24

CDC. Antimicrobial use and resistance (AUR) module. 2013. Accessed Jul 19, 2016

Chen IL, et al. Antibiotic consumption and healthcare-associated infections caused by multidrug- resistant gram-negative bacilli at a large medical center in Taiwan from 2002 to 2009: implicating the importance of antibiotic stewardship. PLoS One 2013;8(5):e65621

Chen YH, et al. Emerging resistance problems and future perspectives in pharmacotherapy for complicated urinary tract infections. Expert Opin Pharmacother 2013 Apr;14(5):587-96

den Heijer CD, et al. The importance of gender-stratified antibiotic resistance surveillance of unselected uropathogens: a Dutch nationwide extramural surveillance study. PLoS One 2013;8:e60497

Deresinski S. The multiple paths to heteroresistance and intermediate resistance to vancomycin in Staphylococcus aureus. J Infect Dis 2013 Jul;208(1):7-9

Farley JE, et al. Prevalence, risk factors, and molecular epidemiology of methicillin-resistant Staphylococcus aureus nasal and axillary colonization among psychiatric patients on admission to an academic medical center. Am J Infect Control 2013 Mar;41(3):199-203

Johnson JR, et al. Abrupt emergence of a single dominant multidrug-resistant strain of Escherichia coli. J Infect Dis 2013 Mar 15;207(6):919-28

Klein EY, et al. The changing epidemiology of methicillin-resistant Staphylococcus aureus in the United States: a national observational study. Am J Epidemiol 2013 Apr 1;177(7):666-74

Klein EY, et al. The potential impact of age and season on methicillin-resistant Staphylococcus aureus prevalence. Future Microbiol 2013 Jul;8(7):809-12

Laxminarayan R, et al. Antibiotic resistance — the need for global solutions. Lancet Infect Dis 2013 Dec;13(12):1057-98

Master RN, et al. Recent trends in resistance to cell envelope-active antibacterial agents among key bacterial pathogens. Ann N Y Acad Sci 2013;1277:1-7

Montassier E, et al. Recent changes in bacteremia in patients with cancer: a systematic review of epidemiology and antibiotic resistance. Eur J Clin Microbiol Infect Dis 2013 Jul;32(7):841-50

Nguyen KV, et al. Antibiotic use and resistance in emerging economies: a situation analysis for Viet Nam. BMC Public Health 2013;13:1158

Popoola VO, et al. Impact of colonization pressure and strain type on methicillin-resistant Staphylococcus aureus transmission in children. Clin Infect Dis 2013 Nov;57(10):1458-60

Popoola VO, et al. Risk factors for persistent methicillin-resistant Staphylococcus aureus colonization in children with multiple intensive care unit admissions. Infect Control Hosp Epidemiol 2013 Jul;34(7):748-50

Savard P, et al. The challenges of carbapenemase-producing Enterobacteriaceae and infection prevention: protecting patients in the chaos. Infect Control Hosp Epidemiol 2013 Jul;34(7):730-9.

Spellberg B, et al. The future of antibiotics and resistance. N Engl J Med 2013 Jan 24;368(4):299-302

Swaminathan M, et al. Prevalence and risk factors for acquisition of carbapenem-resistant Enterobacteriaceae in the setting of endemicity. Infect Control Hosp Epidemiol 2013 Aug;34(8):809-17

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2012

Aldeyab MA, et al. The impact of antibiotic use on the incidence and resistance pattern of extended- spectrum beta-lactamase-producing bacteria in primary and secondary healthcare settings. Br J Clin Pharmacol 2012 Jul;74(1):171-9

Klein E, et al. Resistance movement: hospital administrators must join the fight against antibiotic overuse. Mod Healthc 2012 Aug 6;42(32):22

Magiorakos AP, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect 2012;18:268-81

Rapp RP, Urban C. Klebsiella pneumoniae carbapenemases in Enterobacteriaceae: history, evolution, and microbiology concerns. Pharmacotherapy 2012;32:399-407

Savard P, et al. A call for action: managing the emergence of multidrug-resistant Enterobacteriaceae in the acute care settings. Curr Opin Infect Dis 2012 Aug;25(4):371-7

Sun L, et al. Seasonality and temporal correlation between community antibiotic use and resistance in the United States. Clin Infect Dis 2012 Sep;55(5):687-94

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2011

Adams-Haduch JM, et al. Molecular epidemiology of carbapenem-nonsusceptible Acinetobacter baumannii in the United States. J Clin Microbiol 2011 Nov;49(11):3849-54

Deresinski S. Cephalosporin-resistant gonorrhea: it’s just a matter of time. AIDS Alert 2011 Oct;26(10):115-6

Eagye KJ, et al. Change in antipseudomonal carbapenem susceptibility in 25 hospitals across 9 years is not associated with the use of ertapenem. J Antimicrob Chemother 2011 Jun;66(6):1392-5

Eagye KJ, et al. Flouoroquinolone use is not associated with the change in imipenem susceptibility of Pseudomonas aeruginosa in 25 hospitals. Adv Ther 2011 Apr;28(4):326-33

Ganguly NK, et al. Rationalizing antibiotic use to limit antibiotic resistance in India. Indian J Med Res 2011 Sep;134:281-94

Grundmann, H, et al. A framework for global surveillance of antibiotic resistance. Drug Resist Updat 2011 Apr;14(2):79-87

Laxminarayan R, et al. Communicating trends in resistance using a drug resistance index. BMJ Open 2011 Nov 14;1(2):e000135

Milstone AM, et al. Methicillin-resistant Staphylococcus aureus colonization and risk of subsequent infection in critically ill children: importance of preventing nosocomial methicillin-resistant Staphylococcus aureus transmission. Clin Infect Dis 2011 Nov;53(9):853-9

Winters HA, et al. Extended-spectrum beta-lactamase-producing bacterial infections in adult solid organ transplant recipients. Ann Pharmacother 2011 Mar;45(3):309-16

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2010

Davey P, et al. Overview of strategies for overcoming the challenge of antimicrobial resistance. Expert Rev Clin Pharmacol 2010 Sep;3(5):667-86

Eggleston K, et al. The global challenge of antimicrobial resistance: insights from economic analysis. Int J Environ Res Public Health 2010;7:3141-9

Furtado GH, et al. Overview perspective of bacterial resistance. Expert Opin Ther Pat 2010 Oct;20(10):1273-6

Hicks LA, et al. Increase in pneumococcus macrolide resistance, USA. Emerg Infect Dis 2010 May;16(5):896-7

Hoffman MS, et al. Increasing resistance of acinetobacter species to imipenem in United States hospitals, 1999-2006. Infect Control Hosp Epidemiol 2010 Feb;31(2):196-7

Hunter PA, et al. Antimicrobial-resistant pathogens in animals and man: prescribing, practices and policies. J Antimicrob Chemother 2010 Feb;65 Suppl1:i3-17

Kallen AJ, et al. Multidrug resistance among gram-negative pathogens that caused healthcare-associated infections reported to the National Healthcare Safety Network, 2006-2008

Maragakis LL, et al. How can we stem the rising tide of multidrug-resistant gram-negative bacilli? Infect Control Hosp Epidemiol 2010 Apr;31(4):338-40

Martin SJ, et al. Antimicrobial resistance: consideration as an adverse drug event. Crit Care Med 2010;38:S155-61

Nseir S, et al. Accuracy of American Thoracic Society/Infectious Diseases Society of America criteria in predicting infection or colonization with multidrug-resistant bacteria at intensive-care unit admission. Clin Microbiol Infect 2010;16:902-8

Tacconelli E, De Angelis G. Fighting antibiotic resistance all over Europe. Expert Rev Anti Infect Ther 2010;8:761-3

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Antimicrobial Use

2016
2015
2014
2013
2012
2011
2010

2016

Al-Yamani A, Khamis F, Al-Zakwani I, et al. Patterns of antimicrobial prescribing in a tertiary care hospital in Oman. Oman Med p 2016 Jan;31(1):35-9

Barlam TF, Soria-Saucedo R, Cabral HJ, et al. Unnecessary antibiotics for acute respiratory tract infections: association with care setting and patient demographics. Open Forum Infect Dis 2016 Jan;3(1):ofw045 

Baysari MT, Lehnbom EC, Li L, et al. The effectiveness of information technology to improve antimicrobial prescribing in hospitals: a systematic review and meta-analysis. Int J Med Inform 2016 Aug;92:15-34

Cai T, Mazzoli S, Lanzafame P, et al. Asymptomatic bacteriuria in clinical urological practice: preoperative control of bacteriuria and management of recurrent UTI. Pathogens 2016 (published online Jan 5)

Castel C, de La Blanchardiere A, Michon J, et al. Study on daptomycin use and implementation of an antimicrobial stewardship program. Int J Clin Pharm 2016 Apr;38(2):421-8

Chaintarli K, Ingle SM, Bhattacharya A, et al. Impact of a United Kingdom-wide campaign to tackle antimicrobial resistance on self-reported knowledge and behaviour change. BMC Public Health 2016 May 12;16(1):393

Charmillon A, Novy E, Agrinier N, et al. The ANTIBIOPERF study: a nationwide cross-sectional survey about practices for beta-lactam administration and therapeutic drug monitoring among critically ill patients in France. Clin Microbiol Infect 2016 (published online May 1)

De Luca M, Dona D, Montagnani C, et al. Antibiotic prescriptions and prophylaxis in Italian children. Is it time to change? Data from the ARPEC project. PLoS One 2016 May 16;11(5):e0154662

Dyar OJ, Beovic B, Vlahovic-Palcevski V, et al. on behalf of ESGAP (the ESCMID [European Society of Clinical Microbiology and Infectious Diseases] Study Group for Antibiotic Policies). How can we improve antibiotic prescribing in primary care? Expert Rev Anti Infect Ther 2016 Apr;14(4):403-13

Fleming-Dutra KE, Hersh AL, Shapiro DJ, et al. Prevalence of inappropriate antibiotic prescriptions among US ambulatory care visits, 2010-2011. JAMA 2016 May 3;315(17):1864-73

Frenk SM, Kit BK, Lukacs SL, et al. Trends in the use of prescription antibiotics: NHANES 1999-2012. J Antimicrob Chemother 2016 Jan;71(1):251-6

Ghazi IM, Nicolau DP, Nailor MD, et al. Antibiotic utilization and opportunities for stewardship among hospitalized patients with Influenza respiratory tract infection. Infect Control Hosp Epidemiol 2016 May;37(5):583-9 

Gillon J, Xu M, Slaughter J, et al. Vancomycin use: room for improvement among hospitalized children. J Pharm Pract 2016 (published online Apr 4)

Grenet J, Davido B, Bouchand F, et al. Evaluating antibiotic therapies prescribed to adult patients in the emergency department. Med Mal Infect 2016 Jun;46(4):207-14

Hahn AW, Jain R, Spach DH. New approaches to antibiotic use and review of recently approved antimicrobial agents. Med Clin North Am 2016 Jul;100(4):911-26

Harris AM, Hicks LA, Qaseem A. Appropriate antibiotic use for acute respiratory tract infection in adults: advice for high-value care from the American college of physicians and the centers for disease control and prevention. Ann Intern Med 2016 Mar 15;164(6):425-34

Heid C, Knobloch MJ, Schulz LT, et al. Use of the health belief model to study patient perceptions of antimicrobial stewardship in the acute care setting. Infect Control Hosp Epidemiol 2016 May;37(5):576-82

Hu Y, Walley J, Chou R, et al. Interventions to reduce childhood antibiotic prescribing for upper respiratory infections: systematic review and meta-analysis. J Epidemiol Community Health 2016 Jun 20. pii: jech-2015-206543

Kelesidis T, Braykov N, Uslan DZ, et al. Indications and types of antibiotic agents used in 6 acute care hospitals, 2009-2010: a pragmatic retrospective observational study. Infect Control Hosp Epidemiol 2016 Jan;37(1):70-9

Marc C, Vrignaud B, Levieux K, et al. Inappropriate prescription of antibiotics in pediatric practice: analysis of the prescriptions in primary care. J Child Health Care 2016 (published online Apr 18)

Marra F, George D, Chong M, et al. Antibiotic prescribing by dentists has increased: why? J Am Dent Assoc 2016 May;147(5):320-7

McDonald ML, Buckley J. Antimicrobial practice patterns for urethroplasty: opportunity for improved stewardship. Urology 2016 (published online Apr 29)

McKay R, Mah A, Law M, et al. Systematic review of factors associated with antibiotic prescribing for respiratory tract infections. Antimicrob Agents Chemother 2016 May;60(7):4106-18

Mohareb AM, Dugas AF, Hsieh YH. Changing epidemiology and management of infectious diseases in US EDs. Am J Emerg Med 2016 (published online Mar 11)

Ness V, Price L, Currie K, et al. Influences on independent nurse prescribers' antimicrobial prescribing behaviour: a systematic review. J Clin Nurse 2016 May;25(9-10):1206-17

Parker HM, Mattick K. The determinants of antimicrobial prescribing among hospital doctors in England: a framework to inform tailored stewardship interventions. Br J Clin Pharmacol 2016 (published online Apr 1)

Ren N, Zhou P, Wen X, et al. Point prevalence survey of antimicrobial use in Chinese hospitals in 2012. Am J Infect Control 2016 Mar 1;44(3):332-9

Roche M, Bornet C, Monges P, et al. Misuse of antibiotics reserved for hospital settings in outpatients: a prospective clinical audit in a university hospital in Southern France. Int J Antimicrob Agents 2016 (published online Apr 25)

Santa-Ana-Tellez Y, Mantel-Teeuwisse AK, Leufkens HG, et al. Effects of over-the-counter sales restriction of antibiotics on substitution with medicines for symptoms relief of cold in Mexico and Brazil: time series analysis. Health Policy Plan 2016 (published online May 26)

Schroder W, Sommer H, Gladstone BP, et al. Gender differences in antibiotic prescribing in the community: a systematic review and meta-analysis. J Antimicrob Chemother 2016 (published online Apr 3)

Shallcross LJ, Freemantle N, Nisar S, et al. A cross-sectional study of blood cultures and antibiotic use in patients admitted from the emergency department: missed opportunities for antimicrobial stewardship. BMC Infect Dis 2016 Apr 18;16(1):166

Sharma S, Bowman C, Alladin-Karan B, et al. Antibiotic prescribing patterns in the pediatric emergency department at Georgetown Public Hospital Corporation: a retrospective chart review. BMC Infect Dis 2016 Apr 19;16(1):170

Teixeira Rodrigues A, Ferreira M, Pineiro-Lamas M, et al. Determinants of physician antibiotic prescribing behavior: a 3 year cohort study in Portugal. Curr Med Res Opin 2016 May;32(5):949-57

Teixeira Rodrigues A, Ferreira M, Roque F, et al. Physicians' attitudes and knowledge concerning antibiotic prescription and resistance: questionnaire development and reliability. BMC Infect Dis 2016 Jan 8;16:7

Versporten A, Bielicki J, Drapier N, et al.; ARPEC project group. The Worldwide Antibiotic Resistance and Prescribing in European Children (ARPEC) point prevalence survey: developing hospital-quality indicators of antibiotic prescribing for children. J Antimicrob Chemother 2016 Apr;71(4):1106-17

Watson JR, Sanchez PJ, Spencer JD, et al. Urinary tract infection and antimicrobial stewardship in the emergency department. Pediatr Emerg Care 2016 (published online Feb 6)

Yoon D, Koo HL, Choe PG, et al. The purpose and appropriateness of carbapenem use in a single university hospital, 2009-2013. Expert Rev Clin Pharmacol 2016 Jun;9(6):863-5 

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2015

Akhloufi H, Streefkerk RH, Melles DC, et al. Point prevalence of appropriate antimicrobial therapy in a Dutch university hospital. Eur J Clin Microbiol Infect Dis 2015 Aug;34(8):1631-7

Alfandari S, Robert J, Pean Y, et al. Antibiotic use and good practice in 314 French hospitals: the 2010 SPA2 prevalence study. Med Mal Infect 2015 Nov-Dec;45(11-12):475-80

Alsan M, Morden NE, Gottlieb JD, et al. Antibiotic use in cold and flu season and prescribing quality: a retrospective cohort study. Med Care 2015 Dec;53(12):1066-71

Barlam TF, Morgan JR, Wetzler LM, et al. Antibiotics for respiratory tract infections: a comparison of prescribing in an outpatient setting. Infect Control Hosp Epidemiol 2015 Feb;36(2):153-9

Batard E, Lecadet N, Goffinet N, et al. High variability among emergency departments in 3rd-generation cephalosporins and fluoroquinolones use for community-acquired pneumonia. Infection 2015 Dec;43(6):681-9

Batard E, Vibet MA, Lemarchand C, et al. Use of broad-spectrum antibiotics in French EDs: different trends for third-generation cephalosporins and fluoroquinolones. Eur J Emerg Med 2015 Sep 29

Cooke J, Stephens P, Ashiru-Oredope D,et al. Longitudinal trends and cross-sectional analysis of English national hospital antibacterial use over 5 years (2008-13): working towards hospital prescribing quality measures. J Antimicrob Chemother 2015 Jan;70(1):279-85

Coon ER, Maloney CG, Shen MW. Antibiotic and diagnostic discordance between ED physicians and hospitalists for pediatric respiratory illness. Hosp Pediatr 2015 Mar;5(3):111-8

Courtenay M, Carter S, Rowbotham S, et al. Antibiotic prescribing in primary care: the need for interprofessional collaboration. J Interprof Care 2015;29(4):404-5

Coxeter P, Del Mar CB, McGregor L, et al. Interventions to facilitate shared decision making to address antibiotic use for acute respiratory infections in primary care. Cochrane Database Syst Rev 2015 Nov 12;(11):CD010907. doi(11):CD010907

Dallas A, Magin P, Morgan S, et al. Antibiotic prescribing for respiratory infections: a cross-sectional analysis of the ReCEnT study exploring the habits of early-career doctors in primary care. Fam Pract 2015 Feb;32(1):49-55

Dalton BR, MacTavish SJ, Bresee LC,et al. Antimicrobial use over a four-year period using days of therapy measurement at a Canadian pediatric acute care hospital. Can J Infect Dis Med Microbiol 2015 Sep-Oct;26(5):253-8

Demirjian A, Sanchez GV, Finkelstein JA, et al. Getting smart about antibiotics. (CDC Grand Rounds) MMWR 2015 Aug 21;64(32):871-3

Filice GA, Drekonja DM, Thurn JR, et al. Diagnostic errors that lead to inappropriate antimicrobial use. Infect Control Hosp Epidemiol 2015 Aug;36(8):949-56

Francois Watkins LK, Sanchez GV, Albert AP, et al. Knowledge and attitudes regarding antibiotic use among adult consumers, adult Hispanic consumers, and health care providers — United States, 2012-2013. MMWR 2015 Jul 24;64(28):767-70

Gerber JS, Prasad PA, Russell Localio A, et al. Variation in antibiotic prescribing across a pediatric primary care network. J Pediatric Infect Dis Soc 2015 Dec;4(4):297-304

Gonzalez-Gonzalez C, Lopez-Vazquez P, Vazquez-Lago JM, et al. Effect of physicians' attitudes and knowledge on the quality of antibiotic prescription: a cohort study. PLoS One 2015 Oct 28;10(10):e0141820

Gualano MR, Gili R, Scaioli G, et al. General population's knowledge and attitudes about antibiotics: a systematic review and meta-analysis. Pharmacoepidemiol Drug Saf 2015 Jan;24(1):2-10

Guo W, He Q, Wang Z, et al. Influence of antimicrobial consumption on gram-negative bacteria in inpatients receiving antimicrobial resistance therapy from 2008-2013 at a tertiary hospital in Shanghai, China. Am J Infect Control 2015 Apr 1;43(4):358-64

Hamilton KW, Gerber JS, Moehring R, et al. Point-of-prescription interventions to improve antimicrobial stewardship. Clin Infect Dis 2015 Apr 15;60(8):1252-8

Hamouda K, Oezkur M, Sinha B, et al. Different duration strategies of perioperative antibiotic prophylaxis in adult patients undergoing cardiac surgery: an observational study. J Cardiothorac Surg 2015 Feb 26;10:25,015-0225-x

Hartley S, Valley S, Kuhn L, et al. Overtreatment of asymptomatic bacteriuria: identifying targets for improvement. Infect Control Hosp Epidemiol 2015 Apr;36(4):470-3

Hassali MA, Kamil TK, Md Yusof FA, et al. General practitioners' knowledge, attitude and prescribing of antibiotics for upper respiratory tract infections in Selangor, Malaysia: findings and implications. Expert Rev Anti Infect Ther 2015 Apr;13(4):511-20

Havey TC, Hull MW, Romney MG, et al. Retrospective cohort study of inappropriate piperacillin-tazobactam use for lower respiratory tract and skin and soft tissue infections: opportunities for antimicrobial stewardship. Am J Infect Control 2015 (published online Jul 6)

Hellman J, Grape M, Ternhag A. Antibiotic consumption among a Swedish cohort of children born in 2006. Acta Paediatr 2015 Oct;104(10):1035-8

Hersh AL, Gerber JS, Hicks LA, et al. Lessons learned in antibiotic stewardship: fluoroquinolone use in pediatrics. J Pediatric Infect Dis Soc 2015 Mar;4(1):57-9

Hicks LA, Bartoces MG, Roberts RM, et al. US outpatient antibiotic prescribing variation according to geography, patient population, and provider specialty in 2011. Clin Infect Dis 2015 May 1;60(9):1308-16

James R, Upjohn L, Cotta M, et al. Measuring antimicrobial prescribing quality in Australian hospitals: development and evaluation of a national antimicrobial prescribing survey tool. J Antimicrob Chemother 2015;70(6):1912-8

Janowski AB, Michaels MG, Martin JM, et al. Piperacillin-tazobactam usage at a tertiary pediatric hospital: an antimicrobial stewardship review. J Pediatric Infect Dis Soc 2015 Jul 13

Jones BE, Sauer B, Jones MM, et al. Variation in outpatient antibiotic prescribing for acute respiratory infections in the veteran population: a cross-sectional study. Ann Intern Med 2015 Jul 21;163(2):73-80

Klein EY, Makowsky M, Orlando M, et al. Influence of provider and urgent care density across different socioeconomic strata on outpatient antibiotic prescribing in the USA. J Antimicrob Chemother 2015 May;70(5):1580-7

Kourlaba G, Kourkouni E, Spyridis N, et al. Antibiotic prescribing and expenditures in outpatient paediatrics in Greece, 2010-13. J Antimicrob Chemother 2015 Aug;70(8):2405-8

Kronman MP, Hersh AL, Gerber JS, et al. Identifying antimicrobial stewardship targets for pediatric surgical patients. J Pediatric Infect Dis Soc 2015 Dec;4(4):e100-8

Larru B, Sulieman SE, Localio R, et al. Frontline clinician knowledge of antimicrobial prescribing in an academic tertiary children's hospital: a point prevalence study. J Pediatric Infect Dis Soc 2015 (published online May 11)

Le Doare K, Barker CI, Irwin A, et al. Improving antibiotic prescribing for children in the resource-poor setting. Br J Clin Pharmacol 2015 Mar;79(3):446-55

Lee C, Walker SA, Daneman N, et al. Point prevalence survey of antimicrobial utilization in a Canadian tertiary-care teaching hospital. J Epidemiol Glob Health 2015 Jun;5(2):143-50

Lee MJ, Kim M, Kim NH, et al. Why is asymptomatic bacteriuria overtreated? A tertiary care institutional survey of resident physicians. BMC Infect Dis 2015 Jul 26;15:289,015-1044-3

Lefebure A, Papy E, Rioux C, et al. Audit of carbapenem prescriptions comparing 2 assessment periods. Med Mal Infect 2015 Jul;45(7):273-8

Lucas PJ, Cabral C, Hay AD, et al. A systematic review of parent and clinician views and perceptions that influence prescribing decisions in relation to acute childhood infections in primary care. Scand J Prim Health Care 2015 Mar;33(1):11-20

Malo S, Bjerrum L, Feja C, et al. Compliance with recommendations on outpatient antibiotic prescribing for respiratory tract infections: the case of Spain. Basic Clin Pharmacol Toxicol 2015 Apr;116(4):337-42

Mangione-Smith R, Zhou C, Robinson JD, et al. Communication practices and antibiotic use for acute respiratory tract infections in children. Ann Fam Med 2015 May-Jun;13(3):221-7

Md Rezal RS, Hassali MA, Alrasheedy AA, et al. Physicians' knowledge, perceptions and behaviour towards antibiotic prescribing: a systematic review of the literature. Expert Rev Anti Infect Ther 2015 May;13(5):665-80

Mueller K, McCammon C, Skrupky L, et al. Vancomycin use in patients discharged from the emergency department: a retrospective observational cohort study. J Emerg Med 2015 Jul;49(1):50-7

Ness V, Malcolm W, McGivern G, et al. Growth in nurse prescribing of antibiotics: the Scottish experience 2007-13. J Antimicrob Chemother 2015 Dec;70(12):3384-9

Osowicki J, Gwee A, Noronha J, et al. Australia-wide point prevalence survey of antimicrobial prescribing in neonatal units: how much and how good? Pediatr Infect Dis J 2015 Aug;34(8):e185-90

Pulcini C, Wencker F, Frimodt-Moller N, et al. European survey on principles of prudent antibiotic prescribing teaching in undergraduate students. Clin Microbiol Infect 2015 Apr;21(4):354-61

Raman G, Avendano E, Berger S, et al. Appropriate initial antibiotic therapy in hospitalized patients with gram-negative infections: systematic review and meta-analysis. BMC Infect Dis 2015 Sep 30;15:395

Reddy SC, Jacob JT, Varkey JB, et al. Antibiotic use in US hospitals: quantification, quality measures and stewardship. Expert Rev Anti Infect Ther. 2015 Jul;13(7):843-54

Roque F, Soares S, Breitenfeld L, et al. Influence of community pharmacists attitudes on antibiotic dispensing behavior: a cross-sectional study in Portugal. Clin Ther 2015 Jan 1;37(1):168-77

Ross RK, Hersh AL, Kronman MP, et al. Cost of antimicrobial therapy across US children's hospitals. Infect Control Hosp Epidemiol 2015 Oct;36(10):1242-4

Saleh EA, Schroeder DR, Hanson AC, et al. Guideline-concordant antibiotic prescribing for pediatric outpatients with otitis media, community-acquired pneumonia, and skin and soft tissue infections in a large multispecialty healthcare system. Clin Res Infect Dis 2015 Jan 10;2(1):1010

Sanchez GV, Fleming-Dutra KE, Hicks LA. Minimizing antibiotic misuse through evidence-based management of outpatient acute respiratory infections. Antimicrob Agents Chemother 2015 Oct;59(10):6673

Shawyer AC, Hatchell AC, Pemberton J, et al. Compliance with published recommendations for postoperative antibiotic management of children with appendicitis: a chart audit. J Pediatr Surg 2015 May;50(5):783-5

Skodvin B, Aase K, Charani E, et al. An antimicrobial stewardship program initiative: a qualitative study on prescribing practices among hospital doctors. Antimicrob Resist Infect Control 2015 Jun 4;4:24

Taylor G, Gravel D, Saxinger L, et al. Prevalence of antimicrobial use in a network of Canadian hospitals in 2002 and 2009. Can J Infect Dis Med Microbiol 2015 Mar-Apr;26(2):85-9

Vanbeek J, Hoffman WW, Huntington MK. Comparison of content and format for upper respiratory illness antibiotic prescribing guideline developed by two Midwestern organizations. S D Med 2015 Jul;68(7):304-7

van Spreuwel PC, Blok H, Langelaar MF, et al. Identifying targets for quality improvement in hospital antibiotic prescribing. Neth J Med 2015 May;73(4):161-8

Vellinga A, Galvin S, Duane S, et al. Intervention to improve the quality of antimicrobial prescribing for urinary tract infection: a cluster randomized trial. CMAJ 2015 (published online Nov 16)

Vora NM, Kubin CJ, Furuya EY. Appropriateness of gram-negative agent use at a tertiary care hospital in the setting of significant antimicrobial resistance. Open Forum Infect Dis 2015 Feb 19;2(1):ofv009

Williams DJ, Edwards KM, Self WH, et al. Antibiotic choice for children hospitalized with pneumonia and adherence to national guidelines. Pediatrics 2015 Jul;136(1):44-52

Yogo N, Haas MK, Knepper BC, et al. Antibiotic prescribing at the transition from hospitalization to discharge: a target for antibiotic stewardship. Infect Control Hosp Epidemiol 2015 Apr;36(4):474-8

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2014

Adler N, Weber H, Gunadasa I, et al. Adherence to therapeutic guidelines for patients with community-acquired pneumonia in Australian hospitals. Clin Med Insights Circ Respir Pulm Med 2014 Sep 14;8:17-20

Charani E, Castro Sanchez E, Holmes A. The role of behavior change in antimicrobial stewardship. Infect Dis Clin North Am 2014 Jun;28(2):169-75

Chaves NJ, Cheng AC, Runnegar N, et al. Analysis of knowledge and attitude surveys to identify barriers and enablers of appropriate antimicrobial prescribing in three Australian tertiary hospitals. Intern Med J 2014 Jun;44(6):568-74

Cooke J, Stephens P, Ashiru-Oredope D. Antibacterial usage in English NHS hospitals as part of a national antimicrobial stewardship programme. Public Health 2014 Aug;128(8):693-7

Covvey JR, Johnson BF, Elliott V, et al. An association between socioeconomic deprivation and primary care antibiotic prescribing in Scotland. J Antimicrob Chemother 2014 Mar;69(3):835-41

Dooling KL, Kandeel A, Hicks LA, et al. Understanding antibiotic use in Minya District, Egypt: physician and pharmacist prescribing and the factors influencing their practices. Antibiotics (Basel) 2014 Jun 20;3(2):233-43

Dooling KL, Shapiro DJ, Van Beneden C, et al. Overprescribing and inappropriate antibiotic selection for children with pharyngitis in the United States, 1997-2010. JAMA Pedatr 2014 Nov;168(11):1073-4

Dreno B, Thiboutot D, Gollnick H, et al. Antibiotic stewardship in dermatology: limiting antibiotic use in acne. Eur J Dermatol 2014 May-Jun;24(3):330-4

Dull RB, Friedman SK, Risoldi ZM, et al. Antimicrobial treatment of asymptomatic bacteriuria in noncatheterized adults: a systematic review. Pharmacotherapy 2014 Sep;34(9):941-60

Dyar OJ, Pulcini C, Howard P, et al. European medical students: a first multicentre study of knowledge, attitudes and perceptions of antibiotic prescribing and antibiotic resistance. J Antimicrob Chemother 2014 Mar;69(3):842-6

Fleming A, Bradly, C, Cullinan S, et al. Antibiotic prescribing in long-term care facilities: a qualitative, multidisciplinary investigation. BMJ Open 2014 Nov 5;4(11):e006442

Fleming-Dutra KE, Shapiro DJ, Hicks LA, et al. Race, otitis media, and antibiotic selection. Pediatrics 2014 Dec;134(6):1059-66

Fridkin S, Baggs J, Fagan R, et al. Vital signs: improving antibiotic use among hospitalized patients. MMWR 2014 Mar 7;63(9):194-200

Glass Kaastra SK, Finley R, Hutchinson J, et al. Longitudinal surveillance of outpatient quinolone antimicrobial use in Canada. Can J Infect Dis Med Microbiol 2014 Mar;25(2):99-102

Glass Kaastra SK, Finley R, Hutchinson J, et al. Provincial and temporal variation in macrolide and lincosamide antimicrobial use by outpatients in Canada, 1995 to 2010. Can J Infect Dis Med Microbiol 2014 Mar;25(2):103-6

Glass Kaastra SK, Finley R, Hutchinson J, et al. Variation in outpatient oral antimicrobial use patterns among Canadian provinces, 2000 to 2010. Can J Infect Dis Med Microbiol 2014 Mar;25(2):95-8

Goff DA, Bauer KA, Mangino, JE. Bad bugs need old drugs: a stewardship program's evaluation of minocycline for multidrug-resistant Acinetobacter baumannii infections. Clin Infect Dis 2014 Dec 1;59(Suppl 6):S381-7

Goffinet N, Lecadet N, Cousin M, et al. Increasing use of third-generation cephalosporins for pneumonia in the emergency department: may some prescriptions be avoided? Eur J Clin Microbiol Infect Dis 2014 Jul;33(7):1095-9

Henard S, Boussat S, Demore B, et al. Comparison of hospital databases on antibiotic consumption in France, for a single management tool. Med Mal Infect 2014 Jul;44(7):308-14

Here HW. Should antibiotics be given prior to outpatient cystoscopy? A plea to urologists to practice antibiotic stewardship. Eur Urol 2014 Apr;65(4):839-42

Hopkins CJ. Inpatient antibiotic consumption in a regional secondary hospital in New Zealand. Intern Med J 2014 Feb;44(2):185-90

Johnson TM, Hawkes J. Awareness of antibiotic prescribing and resistance in primary dental care. Prim Dent J 2014 Nov;3(4):44-7

Justo JA, Gauthier TP, Scheetz MH, et al. Knowledge and attitudes of doctor of pharmacy students regarding the appropriate use of antimicrobials. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S162-9

Kandeel A, El Shoubary W, Hicks LA, et al. Patient attitudes and beliefs and provider practices regarding antibiotic use for acute respiratory tract infections in Minya, Egypt. Antibiotics (Basel) 2014 Nov 14;3(4):632-44

Kronman MP, Zhou C, Mangione Smith R. Bacterial prevalence and antimicrobial prescribing trends for acute respiratory tract infections. Pediatrics 2014 Oct;134(4):e956-65

Laxminarayan R, Van Boeckel TP. The value of tracking antibiotic consumption. Lancet Infect Dis 2014 May;14(5):360-1

Leyenaar JK, Lagu T, Shieh MS, et al. Variation in resource utilization for the management of uncomplicated community-acquired pneumonia across community and children's hospitals. J Pediatr 2014 Sep;165(3):585-91

May L, Gudger G, Armstrong P, et al. Multisite exploration of clinical decision making for antibiotic use by emergency medicine providers using quantitative and qualitative methods. Infect Control Hosp Epidemiol 2014 Sep;35(9):1114-25

McLaughlin MM, Pentoney Z, Skoglund E, et al. Projections for antiinfective drug shortages and time to actual resolution. Am J Health Syst Pharm 2014 Dec 1;71(23):2074-8

Pallin DJ, Camargo CA Jr, Schuur JD. Skin infections and antibiotic stewardship: analysis of emergency department prescribing practices, 2007-2010. West J Emerg Med 2014 May;15(3):282-9

Pogue JM, Neelakanta A, Mynatt RP, et al. Carbapenem-resistance in gram-negative bacilli and intravenous minocycline: an antimicrobial stewardship approach at the Detroit Medical Center. Clin Infect Dis 2014 Dec 1;59(Suppl 6):S388-93

Pulcini C, Botelho-Nevers E, Dyar OJ, et al. The impact of infectious disease specialists on antibiotic prescribing in hospitals. Clin Microbiol Infect 2014 Oct;20(10):963-72

Raman G, Avendano E, Berger S, et al. Initial inappropriate antibiotic therapy in hospitalized patients with gram-negative infections: systematic review and meta-analysis. Value Health 2014 Nov;17(7):A667

Sanchez GV, Hicks LA. Acute sinusitis and pharyngitis as inappropriate indications for antibiotic use. Antimicrob Agents Chemother 2014 Jun;58(6):3572

Sanchez GV, Roberts RM, Albert AP, et al. Effects of knowledge, attitudes, and practices of primary care providers on antibiotic selection, United States. Emerg Infect Dis 2014 Dec;20(12):2041-7

Schultz L, Lowe TJ, Srinivasan A, et al. Economic impact of redundant antimicrobial therapy in US hospitals. Infect Control Hosp Epidemiol 2014 Oct;35(10):1229-35

Shapiro DJ, Hicks LA, Pavia AT, et al. Antibiotic prescribing for adults in ambulatory care in the USA, 2007-09. J Antimicrob Chemother 2014 Jan;69(1):234-40

Short E, Esterly J, Postelnick M, et al. Disposition of linezolid or daptomycin in Enterococcal bloodstream infections according to vancomycin resistant Enterococcus colonization. Antimicrob Resist Infect Control 2014 Dec 1;3(1):37

Siddiqui NU, Qamar FN, Jurair H, et al. Multi-drug resistant gram negative infections and use of intravenous polymyxin B in critically ill children of developing country: retrospective cohort study. BMC Infect Dis 2014 Nov 28;14:626

Suda KJ, Hicks LA, Roberts RM, et al. Trends and seasonal variation in outpatient antibiotic prescription rates in the United States, 2006 to 2010. Antimicrob Agents Chemother 2014 May;58(5):2763-6

Talaat M, Saied T, Kandeel A, et al. A point prevalence zurvey of antibiotic use in 18 hospitals in Egypt. Antibiotics (Basel) 2014 Sep 10;3(3):450-60

Valerio M, Rodriguez Gonzalez CG, Munoz P, et al. Evaluation of antifungal use in a tertiary care institution: antifungal stewardship urgently needed. J Antimicrob Chemother 2014 Jul;69(7):1993-9

Van Boeckel TP, Gandra S, Ashok A, et al. Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data. Lancet Infect Dis 2014 Aug;14(8):742-50

Wortham JM, Shapiro DJ, Hersh AL, et al. Burden of ambulatory visits and antibiotic prescribing patterns for adults with community-acquired pneumonia in the United States, 1998 through 2009. JAMA Intern Med 2014 Sep;174(9):1520-2

Wright AJ, Marra F, Chong M, et al. Increased moxifloxacin utilization associated with an unrestricted addition to a drug reimbursement formulary: a population-based analysis. Can J Infect Dis Med Microbiol 2014 Spring;25(1):27-31

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2013

Akar A, et al. Appropriateness and safety of outpatient parenteral antimicrobial therapy in children: opportunities for pediatric antimicrobial stewardship. Clin Pediatr (Phila) 2013 Nov 6. [Epub ahead of print]

Al-Tawfiq JA, et al. The pattern and impact of infectious diseases consultation on antimicrobial prescription. J Glob Infect Dis 2013 Apr;5(2):45-8

Ambroggio L, et al. Quality improvement methods increase appropriate antibiotic prescribing for childhood pneumonia. Pediatrics 2013 May;131(5):e1623-31

Barr DA, et al. Outpatient parenteral antimicrobial therapy (OPAT) and the general physician. Clin Med 2013 Oct;13(5):495-9

Bartlett JG. How important are anaerobic bacteria in aspiration pneumonia: when should they be treated and what is optimal therapy. Infect Dis Clin North Am 2013 Mar;27(1):149-55

Cairns KA, et al. Prescribing trends before and after implementation of an antimicrobial stewardship program. Med J Aust 2013;198:262-6

Calbo E, et al. A review of the factors influencing antimicrobial prescribing. Enferm Infecc Microbiol Clin 2013 Sep;31(Suppl 4):12-5

Casapao AM, et al. Multicenter study of high-dose daptomycin for treatment of enterococcal infections. Antimicrob Agents Chemother 2013 Sep; 57(9):4190-6

Charani E, et al. Understanding the determinants of antimicrobial prescribing within hospitals: the role of "prescribing etiquette." Clin Infect Dis 2013 Jul;57(2):188-96

Dyar OJ, et al. Knowledge, attitudes, and beliefs of French medical students about antibiotic prescribing and resistance. Med Mal Infect 2013 Oct;43(10):423-30

Evans CT, et al. Antibiotic prescribing trends in the emergency department for veterans with spinal cord injury and disorder 2002-2007. J Spinal Cord Med 2013 Sep;36(5):492-8

Gerber JS, et al. Effect of an outpatient antimicrobial stewardship intervention on broad-spectrum antibiotic prescribing by primary care pediatricians: a randomized trial. JAMA 2013 Jun 12;309(22):2345-52

Graber CJ, et al. Unnecessary antimicrobial use in the context of Clostridium difficile infection: a call to arms for the Veterans Affairs Antimicrobial Stewardship Task Force. Infect Control Hosp Epidemiol 2013 Jun;34(6):651-3

Hurley HJ, et al. Avoidable antibiotic exposure for uncomplicated skin and soft tissue infections in the ambulatory care setting. Am J Med 2013 Dec;126(12):1099-106

Lai A, et al. Outpatient parenteral antimicrobial therapy at large veterans administration medical center. Am J Manag Care 2013 Sep;19(9):e317-24

Li S, et al. Are physicians’ prescribing decisions sensitive to drug prices? Evidence from a free-antibiotics program. Health Econ 2015 Feb;24(2):158-74

Lopez-Medrano F, et al. How to assist clinicians in improving antimicrobial prescribing: tools and interventions provided by stewardship programs. Enferm Infecc Microbiol Clin 2013 Sep;31(Suppl 4):38-44

Madigan T, et al. Characteristics and outcomes of outpatient parenteral antimicrobial therapy at an academic children's hospital. Pediatr Infect Dis J 2013 Apr;32(4):346-9

Peron EP, et al. Another setting for stewardship: high rate of unnecessary antimicrobial use in a veterans affairs long-term care facility. J Am Geriatr Soc 2013 Feb;61(2):289-90

Pulcini C, et al. Drug-specific quality indicators assessing outpatient antibiotic use among French general practitioners. Eur J Public Health 2013 Apr;23(2):262-4

Retamar P, et al. Evaluating the quality of antimicrobial prescribing: is standardisation possible? Enferm Infecc Microbiol Clin 2013 Sep;31(Suppl 4):25-30

Rimawi RH, et al. Impact of regular collaboration between infectious diseases and critical care practitioners on antimicrobial utilization and patient outcome. Crit Care Med 2013 Sep;41(9):2099-107

Schweizer ML, et al. Optimizing antimicrobial prescribing: Are clinicians following national trends in methicillin-resistant staphylococcus aureus (MRSA) infections rather than local data when treating MRSA wound infections. Antimicrob Resist Infect Control 2013 Oct 15;2(1):28

Wertheim H, et al. Global survey of polymyxin use: a call for international guidelines. J Glob Antimicrob Resist 2013 Sep;1(3):131-134

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2012

Ashiru-Oredope D, et al. Improving the quality of antibiotic prescribing in the NHS by developing a new Antimicrobial Stewardship Programme: Start Smart--Then Focus. J Antimicrob Chemother 2012;67(Suppl 1):i51-63

Barr DA, et al. Outpatient parenteral antimicrobial therapy (OPAT) in a teaching hospital-based practice: a retrospective cohort study describing experience and evolution over 10 years. Int J Antimicrob Agents 2012 May;39(5):407-13

Cano EL, et al. Incidence of nephrotoxicity and association with vancomycin use in intensive care unit patients with pneumonia: retrospective analysis of the IMPACT-HAP Database. Clin Ther 2012;34:149-57

Fairlie T, et al. National trends in visit rates and antibiotic prescribing for adults with acute sinusitis. Arch Intern Med 2012 Oct 22;172(19):1513-4

Huttner B, et al. Double trouble: how big a problem is redundant anaerobic antibiotic coverage in Veterans Affairs medical centres? J Antimicrob Chemother 2012;67:1537-9

Roberts RM, et al. Appropriate antibiotic use: family physicians have the power of the pen. Am Fam Physician 2012 Nov 1;86(9):810

Suda KJ, et al. A national evaluation of antibiotic expenditures by healthcare setting in the United States, 2009. J Antimicrob Chemother 2013 Mar;68(3):715-8

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2011

Aldeyab MA, et al. A point prevalence survey of antibiotic prescriptions: benchmarking and patterns of use. Br J Clin Pharmacol 2011;71:293-6

Etienne P, et al. Antimicrobial stewardship program and quality of antibiotic prescriptions. Med Mal Infect 2011;41:608-12

Hicks LA, et al. Outpatient antibiotic prescribing and nonsusceptible Streptococcus pneumoniae in the United States, 1996-2003. Clin Infect Dis 2011 Oct;53(7):631-9

Kiyatkin DE, et al. Improving utilization of antimicrobial drugs among physician assistants in the ED. JAAPA 2011;24:44, 47-8, 50-1

Leekha S, et al. General principles of antimicrobial therapy. Mayo Clin Proc 2011;86:156-67

Montravers P,et al. Strategies of initiation and streamlining of antibiotic therapy in 41 French intensive care units. Crit Care 2011;15:R17

Ozgenç O, et al. Evaluation of the therapeutic use of antibiotics in Aegean Region hospitals of Turkey: a multicentric study. Indian J Med Microbiol 2011;29:124-9

Parienti JJ, et al. Hospital-wide modification of fluoroquinolone policy and methicillin-resistant Staphylococcus aureus rates: a 10-year interrupted time-series analysis. J Hosp Infect 2011;78:118- 22

Polk RE, et al. Benchmarking risk-adjusted adult antibacterial drug use in 70 US academic medical center hospitals. Clin Infect Dis 2011;53:1100-10

Schwartz DN, et al. Deriving measures of intensive care unit antimicrobial use from computerized pharmacy data: methods, validation, and overcoming barriers. Infect Control Hosp Epidemiol 2011 May;32(5):472-80

Seyler L, et al. Recommended beta-lactam regimens are inadequate in septic patients treated with continuous renal replacement therapy. Crit Care 2011;15:R137

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2010

Bhavnani SM, et al. Daptomycin exposure and the probability of elevations in the creatinine phosphokinase level: data from a randomized trial of patients with bacteremia and endocarditis. Clin Infect Dis 2010;50:1568-74

Bjerrum L, et al. Health alliance for prudent prescribing, yield and use of antimicrobial drugs in the treatment of respiratory tract infections (HAPPY AUDIT). BMC Fam Pract 2010;11:29

Di Pentima MC, Chan S. Impact of antimicrobial stewardship program on vancomycin use in a pediatric teaching hospital. Pediatr Infect Dis J 2010;29:707-11

Dryden M, et al. A European survey of antibiotic management of methicillin-resistant Staphylococcus aureus infection: current clinical opinion and practice. Clin Microbiol Infect 2010 Mar;16 Suppl 1:3-30

Frei CR, et al. Guideline-concordant antibiotic use and survival among patients with community- acquired pneumonia admitted to the intensive care unit. Clin Ther 2010;32:293-9

McNulty CA, Francis NA. Optimizing antibiotic prescribing in primary care settings in the UK: findings of a BSAC multi-disciplinary workshop 2009. J Antimicrob Chemother 2010;65:2278-84

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Stewardship: Guidance, Consensus

2016
2015
2014
2013
2012
2011

2016

Barlam TF, Cosgrove SE, Abbo LM, et al. Executive summary: implementing an antibiotic stewardship program: guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. Clin Infect Dis 2016 May 15;62(10):1197-202

Barlam TF, Cosgrove SE, Abbo LM, et al. Implementing an antibiotic stewardship program: guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. Clin Infect Dis 2016 May 15;62(10):e51-77

de With K, Allerberger F, Amann S, et al. Strategies to enhance rational use of antibiotics in hospital: a guideline by the German Society for Infectious Diseases. Infection 2016 Jun;44(3):395-439

Chinese XDR Consensus Working Group. Laboratory diagnosis, clinical management and infection control of the infections caused by extensively drug-resistant Gram-negative bacilli: a Chinese consensus statement. Clin Microbiol Infect 2016 Mar;22(Suppl 1):S15-25

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2015

Miyazaki T, Kohno S. Current recommendations and importance of antifungal stewardship for the management of invasive candidiasis. Expert Rev Anti Infect Ther 2015;13(9):1171-83

Patel S, Abrahamson E, Goldring S, et al. Good practice recommendations for paediatric outpatient parenteral antibiotic therapy (p-OPAT) in the UK: a consensus statement. J Antimicrob Chemother 2015 Feb;70(2):360-73

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2014

Ashiru-Oredope D, Cookson B, Fry C, et al. Developing the first national antimicrobial prescribing and stewardship competences. J Antimicrob Chemother 2014 Nov;69(11):2886-8

Chang CC, Ananda Rajah M, Belcastro A, et al. Consensus guidelines for implementation of quality processes to prevent invasive fungal disease and enhanced surveillance measures during hospital building works, 2014. Intern Med J 2014 Dec;44(12b):1389-97

Cosgrove SE, Hermsen ED, Rybak MJ, et al. Guidance for the knowledge and skills required for antimicrobial stewardship leaders. Infect Control Hosp Epidemiol 2014 Dec;35(12):1444-51

Couch KA, Geide T. ASHP therapeutic position statement on strategies for identifying and preventing pneumococcal resistance. Am J Health Syst Pharm 2014 Mar 1;71(5):417-24

Fridkin SK, Srinivasan A. Implementing a strategy for monitoring inpatient antimicrobial use among hospitals in the United States. Clin Infect Dis 2014 Feb;58(3):401-6

Mehta Y, Gupta A, Todi S, et al. Guidelines for prevention of hospital acquired infections. Indian J Crit Care Med 2014 Mar;18(3):149-63

Pollack LA, Srinivasan A. Core elements of hospital antibiotic stewardship programs from the Centers for Disease Control and Prevention. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S97-100

Septimus E, Yokoe DS, Weinstein RA, et al. Maintaining the momentum of change: the role of the 2014 updates to the compendium in preventing healthcare-associated infections. Infect Control Hosp Epidemiol 2014 Sep;35(Suppl 2):S6-9

Thern J, de With K, Strauss R, et al. Selection of hospital antimicrobial prescribing quality indicators: a consensus among German antibiotic stewardship (ABS) networkers. Infection 2014 Apr;42(2):351-62

Yokoe DS, Anderson DJ, Berenholtz SM, et al. A compendium of strategies to prevent healthcare-associated infections in acute care hospitals: 2014 updates. Infect Control Hosp Epidemiol 2014 Sep;35(Suppl 2):S21-31

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2013

Bratzler DW, et al. Clinical practice guidelines for antimicrobial prophylaxis in surgery. Surg Infect (Larchmt) 2013 Feb;14(1):73-156

Hersh AL, et al. Principles of judicious antibiotic prescribing for upper respiratory tract infections in pediatrics. Pediatrics 2013 Dec;132(6):1146-54

Holmes AH, et al. The Chennai Declaration: India's landmark national commitment to antibiotic stewardship demonstrates that 'truth alone triumphs.' J Antimicrob Chemother 2013 Jul;68(7):1453-4

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2012

Chapman AL, et al. Good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults in the UK: a consensus statement. J Antimicrob Chemother 2012 May;67(5):1053-62

FDA. The judicious use of medically important antimicrobial drugs in food-producing animals. Guidance for industry (#209).  Apr 13, 2012 [See also: FDA. New animal drugs and new animal drug combination products administered in or on medicated feed or drinking water of food-producing animals: recommendations for drug sponsors for voluntarily aligning product use conditions with GFI #209. December 2013]

FDA. Safety and innovation act. Accessed July 2016.

IDSA/SHEA/PIDS. Policy statement on antimicrobial stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS). Infect Control Hosp Epidemiol 2012 Apr;33(4):322-7

Patient Centered Outcomes Research Institute. Draft national priorities for research and research agenda, version 1. Jan 23, 2012

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2011

IDSA. Combating antimicrobial resistance: policy recommendations to save lives. Clin Infect Dis 2011;52:S397-S428

McIntosh KA, et al. A quality improvement initiative to improve adherence to national guidelines for empiric management of community-acquired pneumonia in emergency departments. Int J Qual Health Care 2011;23:142-50

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Stewardship: Health Policy

2016
2015
2014
2013
2012
2011
2010

2016

Ardal C, Outterson K, Hoffman SJ, et al. International cooperation to improve access to and sustain effectiveness of antimicrobials. Lancet 2016 Jan 16;387(10015):296-307

Ashiru-Oredope D, Budd EL, Bhattacharya A, et al.; English Surveillance Programme for Antimicrobial Utilisation and Resistance (ESPAUR). Implementation of antimicrobial stewardship interventions recommended by national toolkits in primary and secondary healthcare sectors in England: TARGET and Start Smart Then Focus. J Antimicrob Chemother 2016 May;71(5):1408-14

Brogan DM, Mossialos E. A critical analysis of the review on antimicrobial resistance report and the infectious disease financing facility. Global Health 2016 Mar 22;12:8

Broom A, Plage S, Broom J, et al. A qualitative study of hospital pharmacists and antibiotic governance: negotiating interprofessional responsibilities, expertise and resource constraints. BMC Health Serv Res 2016 Feb 6;16:43

Castro-Sanchez E, Drumright LN, Gharbi M, et al. Mapping antimicrobial stewardship in undergraduate medical, dental, pharmacy, nursing and veterinary education in the United Kingdom. PLoS One 2016 Feb;11(2):e0150056

Chuenchom N, Thamlikitkul V, Chaiwarith R, et al. Perception, attitude, and knowledge regarding antimicrobial resistance, appropriate antimicrobial use, and infection control among future medical practitioners: a multicenter study. Infect Control Hosp Epidemiol 2016 May;37(5):603-5

Chou AF, Graber CJ, Jones M, et al. Characteristics of antimicrobial stewardship programs at Veterans Affairs hospitals: results of a nationwide survey. Infect Control Hosp Epidemiol 2016 Jun;37(6):647-54

Dar OA, Hasan R, Schlundt J, et al. Exploring the evidence base for national and regional policy interventions to combat resistance. Lancet 2016 Jan 16;387(10015):285-95

Essack SY, Desta AT, Abotsi RE, et al. Antimicrobial resistance in the WHO African region: current status and roadmap for action. J Public Health (Oxf) 2016 (published online Mar 3)

Goff DA, File TM Jr. The evolving role of antimicrobial stewardship in management of multidrug resistant infections. Infect Dis Clin North Am 2016 Jun;30(2):539-51

Holloway KA, Rosella L, Henry D. The impact of WHO essential medicines policies on inappropriate use of antibiotics. PLoS One 2016 Mar 22;11(3):e0152020

Jacobs DM, Kuper K, Septimus E, et al. Assessment of antimicrobial stewardship activities in a large metropolitan area. J Pharm Pract 2016 Jun;29(3):188-93

Kostyanev T, Bonten MJ, O'Brien S, et al. The innovative medicines initiative's new drugs for bad bugs programme: European public-private partnerships for the development of new strategies to tackle antibiotic resistance. J Antimicrob Chemother 2016 Feb;71(2):290-5

Laxminarayan R, Matsoso P, Pant S, et al. Access to effective antimicrobials: a worldwide challenge. Lancet 2016 Jan 9;387(10014):168-75

Mendelson M, Rottingen JA, Gopinathan U, et al. Maximising access to achieve appropriate human antimicrobial use in low-income and middle-income countries. Lancet 2016 Jan 9;387(10014):188-98

Morgan DJ, Croft LD, Deloney V, et al. Choosing wisely in healthcare epidemiology and antimicrobial stewardship. Infect Control Hosp Epidemiol 2016 Mar;37(7):755-60

Olans RN, Olans RD, DeMaria A Jr. The critical role of the staff nurse in antimicrobial stewardship — unrecognized, but already there. Clin Infect Dis 2016 Jan 1;62(1):84-9

Outterson K, McDonnell A. Funding antibiotic innovation with vouchers: recommendations on how to strengthen a flawed incentive policy. Health Aff (Millwood) 2016 May 1;35(5):784-90

Pollack LA, van Santen KL, Weiner LM, et al. Antibiotic stewardship programs in U.S. acute care hospitals: findings from the 2014 National Healthcare Safety Network (NHSN) Annual Hospital Survey. Clin Infect Dis 2016 (published online May 19)

Premanandh J, Samara BS, Mazen AN. Race against antimicrobial resistance requires coordinated action — an overview. Front Microbiol 2016 Feb;6:1536

Rawson TM, Moore LS, Gilchrist MJ, et al. Antimicrobial stewardship: are we failing in cross-specialty clinical engagement? J Antimicrob Chemother 2016 Feb;71(2):554-9

Spyridis N, Syridou G, Goossens H, et al.; ARPEC Project Group Members. Variation in paediatric hospital antibiotic guidelines in Europe. Arch Dis Child 2016 Jan;101(1):72-6

Steinberg M, Dresser LD, Daneman N, et al. A national survey of critical care physicians' knowledge, attitudes, and perceptions of antimicrobial stewardship programs. J Intensive Care Med 2016 Jan;31(1):61-5

Tacconelli E, Cataldo MA, Paul M, et al. STROBE-AMS: recommendations to optimise reporting of epidemiological studies on antimicrobial resistance and informing improvement in antimicrobial stewardship. BMJ Open 2016 Feb 19;6(2):e010134

Thompson W, Sandoe JA. What does NICE have to say about antimicrobial prescribing to the dental community? Br Dent J 2016 Feb 26;220(4):193-5

Wong D, Spellberg B. Leveraging antimicrobial stewardship into improving rates of carbapenem-resistant Enterobacteriaceae. Virulence 2016 (published online May 17)

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2015

Alsan M, Schoemaker L, Eggleston K, et al. Out-of-pocket health expenditures and antimicrobial resistance in low-income and middle-income countries: an economic analysis. Lancet Infect Dis 2015 Oct;15(10):1203-10

Altiner A, Bell J, Duerden M, et al. More action, less resistance: report of the 2014 summit of the Global Respiratory Infection Partnership. Int J Pharm Pract 2015 Oct;23(5):370-7

Aryee A, Price N. Antimicrobial stewardship — can we afford to do without it? Br J Clin Pharmacol 2015 Feb;79(2):173-81

Ashiru-Oredope D, Hopkins S. Antimicrobial resistance: moving from professional engagement to public action. J Antimicrob Chemother 2015 Nov;70(11):2927-30

Bao L, Peng R, Wang Y, et al. Significant reduction of antibiotic consumption and patients' costs after an action plan in China, 2010-2014. PLoS One 2015 Mar 13;10(3):e0118868

Barriere SL. Clinical, economic and societal impact of antibiotic resistance. Expert Opin Pharmacother 2015 Feb;16(2):151-3

Bishop BM. Antimicrobial stewardship in the emergency department: challenges, opportunities, and a call to action for pharmacists. J Pharm Pract 2015 (published online Jun 1)

Brair A, Toozs-Hobson P, Gray J. Local audit: how tightly should we police antibiotic prescribing for urinary tract infection and how should we modify national policy? Post Reprod Health 2015 Dec;21(4):151-7

Bretonniere C, Leone M, Milesi C, et al. Strategies to reduce curative antibiotic therapy in intensive care units (adult and paediatric). Intensive Care Med 2015 Jul;41(7):1181-96

Broom A, Broom J, Kirby E, et al. What role do pharmacists play in mediating antibiotic use in hospitals? A qualitative study. BMJ Open 2015 Nov 3;5(11):e008326,2015-008326

Broom A, Broom J, Kirby E, et al. The path of least resistance? Jurisdictions, responsibility and professional asymmetries in pharmacists' accounts of antibiotic decisions in hospitals. Soc Sci Med 2015 Dec;146:95-103

Bryant PA, Australasian Stewardship of Antimicrobials in Paediatrics group. Antimicrobial stewardship resources and activities for children in tertiary hospitals in Australasia: a comprehensive survey. Med J Aust 2015 Feb 16;202(3):134-8

Buick S, Joffe AM, Taylor G, et al. A consensus development conference model for establishing health policy for surveillance and screening of antimicrobial-resistant organisms. Clin Infect Dis 2015 Apr 1;60(7):1095-101

Cairns KA, Roberts JA, Cotta MO, et al. Antimicrobial stewardship in Australian hospitals and other settings. Infect Dis Ther 2015 Sep;4(Suppl 1):27-38

Cakmakci M. Antibiotic stewardship programmes and the surgeon's role. J Hosp Infect 2015 Apr;89(4):264-6

Chahine EB, El-Lababidi RM, Sourial M. Engaging pharmacy students, residents, and fellows in antimicrobial stewardship. J Pharm Pract 2015 Dec;28(6):585-91

Cheng VC, Wong SC, Ho PL, et al. Strategic measures for the control of surging antimicrobial resistance in Hong Kong and mainland of China. Emerg Microbes Infect 2015 Feb;4(2):e8

Colligan C, Sneddon J, Bayne G, et al. Six years of a national antimicrobial stewardship programme in Scotland: where are we now? Antimicrob Resist Infect Control 2015 Jun 29;4:28

Daulaire N, Bang A, Tomson G, et al. Universal access to effective antibiotics is essential for tackling antibiotic resistance. J Law Med Ethics 2015 Summer;43(Suppl 3):17-21

Davey P, Peden C, Charani E, et al. Time for action — improving the design and reporting of behaviour change interventions for antimicrobial stewardship in hospitals: early findings from a systematic review. Int J Antimicrob Agents 2015 Mar;45(3):203-12

Fleming A, Tonna A, O'Connor S, et al. Antimicrobial stewardship activities in hospitals in Ireland and the United Kingdom: a comparison of two national surveys. Int J Clin Pharm 2015 Oct;37(5):776-81

Gelband H, Laxminarayan R. Tackling antimicrobial resistance at global and local scales. Trends Microbiol 2015 Sep;23(9):524-6

Gilchrist M, Wade P, Ashiru-Oredope D, et al. Antimicrobial stewardship from policy to practice: experiences from UK antimicrobial pharmacists. Infect Dis Ther 2015 Sep;4(Suppl 1):51-64

Goff DA, Rybak MJ. Global antimicrobial stewardship; challenges and success from frontline stewards. Infect Dis Ther 2015 Sep;4(Suppl 1):1-3

Goldman JL, Newland JG. New horizons for pediatric antibiotic stewardship. Infect Dis Clin North Am 2015 Sep;29(3):503-11

Hersh AL, De Lurgio SA, Thurm C, et al. Antimicrobial stewardship programs in freestanding children's hospitals. Pediatrics 2015 Jan;135(1):33-9

Howard P, Pulcini C, Levy Hara G, et al. An international cross-sectional survey of antimicrobial stewardship programmes in hospitals. J Antimicrob Chemother 2015 Apr;70(4):1245-55

James R, Luu S, Avent M, et al. A mixed methods study of the barriers and enablers in implementing antimicrobial stewardship programmes in Australian regional and rural hospitals. J Antimicrob Chemother 2015 Sep;70(9):2665-70

Jeffs L, Thampi N, Maione M, et al. A qualitative analysis of implementation of antimicrobial stewardship at 3 academic hospitals: Understanding the key influences on success. Can J Hosp Pharm 2015 Sep-Oct;68(5):395-400

Johnson AP, Ashiru-Oredope D, Beech E. Antibiotic stewardship initiatives as part of the UK 5-year antimicrobial resistance strategy. Antibiotics (Basel) 2015 Oct 30;4(4):467-79

Kelly R, Zoubiane G, Walsh D, et al. Public funding for research on antibacterial resistance in the JPIAMR countries, the European Commission, and related European Union agencies: a systematic observational analysis. Lancet Infect Dis 2015 (published online Dec 18)

Kim J, Craft DW, Katzman M. Building an antimicrobial stewardship program: cooperative roles for pharmacists, infectious diseases specialists, and clinical microbiologists. Lab Med 2015 Summer;46(3):e65-71

Lambert ML, Bruyndonckx R, Goossens H, et al. The Belgian policy of funding antimicrobial stewardship in hospitals and trends of selected quality indicators for antimicrobial use, 1999-2010: a longitudinal study. BMJ Open 2015 Feb 13;5(2):e006916

Lee CR, Lee JH, Kang LW, et al. Educational effectiveness, target, and content for prudent antibiotic use. Biomed Res Int 2015;2015:214021

Magsarili HK, Girotto JE, Bennett NJ, et al. Making a case for pediatric antimicrobial stewardship programs. Pharmacotherapy 2015 Nov;35(11):1026-36

Manning ML, Giannuzzi D. Keeping patients safe: antibiotic resistance and the role of nurse executives in antibiotic stewardship. J Nurs Adm 2015 Feb;45(2):67-9

Mendelson M, Rottingen JA, Gopinathan U, et al. Maximising access to achieve appropriate human antimicrobial use in low-income and middle-income countries. Lancet 2015 (published online Nov 18)

Olans RD, Nicholas PK, Hanley D, et al. Defining a role for nursing education in staff nurse participation in antimicrobial stewardship. J Contin Educ Nurs 2015 Jul;46(7):318-21

Olans RN, Olans RD, DeMaria A, Jr. The critical role of the staff nurse in antimicrobial stewardship--unrecognized, but already there. Clin Infect Dis 2015 (published online Aug 11)

Perez F, Villegas MV. The role of surveillance systems in confronting the global crisis of antibiotic-resistant bacteria. Curr Opin Infect Dis 2015 Aug;28(4):375-83

Pogorzelska-Maziarz M, Herzig CT, Larson EL, et al. Implementation of antimicrobial stewardship policies in US hospitals: findings from a national survey. Infect Control Hosp Epidemiol 2015 Mar;36(3):261-4

Roger PM, Courjon J, Leotard S, et al. Antimicrobial stewardship policy: time to revisit the strategy? Eur J Clin Microbiol Infect Dis 2015 Nov;34(11):2167-70

Shallcross LJ, Howard SJ, Fowler T, et al. Tackling the threat of antimicrobial resistance: from policy to sustainable action. Philos Trans R Soc Lond B Biol Sci 2015 Jun 5;370(1670):20140082

Spyridis N, Syridou G, Goossens H, et al. Variation in paediatric hospital antibiotic guidelines in Europe. Arch Dis Child 2015 (published online Sep 28)

Trinh TD, Klinker KP. Antimicrobial stewardship in the emergency department. Infect Dis Ther 2015 Sep;4(Suppl 1):39-50

Viale P, Giannella M, Bartoletti M, et al. Considerations about antimicrobial stewardship in settings with epidemic extended-spectrum beta-lactamase-producing or carbapenem-resistant Enterobacteriaceae. Infect Dis Ther 2015 Sep;4(Suppl 1):65-83

Viens AM, Littmann J. Is antimicrobial resistance a slowly emerging disaster? Public Health Ethics 2015 Nov;8(3):255-65

Welch S. Antimicrobial stewardship in Australian emergency departments. Emerg Med Australas 2015 Oct;27(5):427-30

Wolf J, Sun Y, Tang L, et al. Antimicrobial stewardship barriers and goals in pediatric oncology and bone marrow transplantation: a survey of antimicrobial stewardship practitioners. Infect Control Hosp Epidemiol 2015 (published online Dec 7)

Zaidi MB, Dreser A, Figueroa IM. A collaborative initiative for the containment of antimicrobial resistance in Mexico. Zoonoses Public Health 2015 Apr;62(Suppl 1):52-7

Zhang YZ, Singh S. Antibiotic stewardship programmes in intensive care units: why, how, and where are they leading us. World J Crit Care Med 2015 Feb 4;4(1):13-28

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2014

Abbo LM, Hooton TM. Antimicrobial stewardship and urinary tract infections. Antibiotics (Basel) 2014 May 5;3(2):174-92

Avent ML, Hall L, Davis L, et al. Antimicrobial stewardship activities: a survey of Queensland hospitals. Aust Health Rev 2014 Nov;38(5):557-63

Banerjee R, Beekmann SE, Doby EH, et al. Outpatient parenteral antimicrobial therapy practices among pediatric infectious diseases consultants: results of an emerging infections network survey. J Pediatric Infect Dis Soc 2014 Mar;3(1):85-8

Borg MA, Hulscher M, Scicluna EA, et al. Prevention of meticillin-resistant Staphylococcus aureus bloodstream infections in European hospitals: moving beyond policies. J Hosp Infect 2014 Aug;87(4):203-11

Bowes J, Yasseen AS 3rd, Barrowman N, et al. Antimicrobial stewardship in pediatrics: focusing on the challenges clinicians face. BMC Pediatr 2014 Aug 27;14:212

Campbell KA, Stein S, Looze C, et al. Antibiotic stewardship in orthopaedic surgery: principles and practice. J Am Acad Orthop Surg 2014 Dec;22(12):772-81

Crader MF. Development of antimicrobial competencies and training for staff hospital pharmacists. Hosp Pharm 2014 Jan;49(1):32-40

Dixon J, Duncan CJ. Importance of antimicrobial stewardship to the English National Health Service. Infect Drug Resist 2014 May 30;7:145-52

Ellingson K, McCormick K, Sinkowitz Cochran R, et al. Enhancement of health department capacity for health care-associated infection prevention through Recovery Act-funded programs. Am J Public Health 2014 Apr;104(4):e27-33

Falcione BA, Meyer SM. Development of an antimicrobial stewardship-based infectious diseases elective that incorporates human patient simulation technology. Am J Pharm Educ 2014 Oct 15;78(8):151

File TM Jr, Srinivasan A, Bartlett JG. Antimicrobial stewardship: importance for patient and public health. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S93-6

Flannery DD, Swami S, Chan S, et al. Prescriber perceptions of a pediatric antimicrobial stewardship program. Clin Pediatr (Phila) 2014 Jul;53(8):747-50

Goff DA, Mendelson M. Is it time for an antibiotic prenuptial agreement? Lancet Infect Dis 2014 Dec;14(12):1168-9

Hamilton KW, Fishman NO. Antimicrobial stewardship interventions: thinking inside and outside the box. Infect Dis Clin North Am 2014 Jun;28(2):301-13

Hanberger H, Skoog G, Ternhag A, et al. Antibiotic consumption and antibiotic stewardship in Swedish hospitals. Ups J Med Sci 2014 May;119(2):154-61

Huttner B, Harbarth S, Nathwani D, et al. Success stories of implementation of antimicrobial stewardship: a narrative review. Clin Microbiol Infect 2014 Oct;20(10):954-62

Laxminarayan R. Antibiotic effectiveness: balancing conservation against innovation. Science 2014 Sep 12;345(6202):1299-301

Le Saux N. Antimicrobial stewardship in daily practice: managing an important resource. Paediatr Child Health 2014 May;19(5):261-70

Le Saux N, Canadian Pediatric Society, Infectious Diseases and Immunization Committee. Antimicrobial stewardship in daily practice: managing an important resource. Can J Infect Dis Med Microbiol 2014 Sep;25(5):241-5

Livermore DM. Of stewardship, motherhood and apple pie. Int J Antimicrob Agents 2014 Apr;43(4):319-22

Llor C, Bjerrum L. Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem. Ther Adv Drug Saf 2014 Dec;5(6):229-41

Luyt CE, Brechot N Trouillet JL, et al. Antibiotic stewardship in the intensive care unit. Crit Care 2014 Aug 13;18(5):480

MacKenzie M, Rae N, Nathwani D. Outcomes from global adult outpatient parenteral antimicrobial therapy programmes: a review of the last decade. Int J Antimicrob Agents 2014 Jan;43(1):7-16

Maechler F, Schwab F, Geffers C, et al. Antibiotic stewardship in Germany: a cross-sectional questionnaire survey of 355 intensive care units. Infection 2014 Feb;42(1):119-25

McKellar MR, Fendrick AM. Innovation of novel antibiotics: an economic perspective. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S104-7

Metz M, Shlaes DM. Eight more ways to deal with antibiotic resistance. Antimicrob Agents Chemother 2014 Aug;58(8):4253-6

Moore LS, Freeman R, Gilchrist MJ, et al. Homogeneity of antimicrobial policy, yet heterogeneity of antimicrobial resistance: antimicrobial non-susceptibility among 108,717 clinical isolates from primary, secondary and tertiary care patients in London. J Antimicrob Chemother 2014 Dec;69(12):3409-22

Nagel JL, Stevenson JG, Eiland EH 3rd, et al. Demonstrating the value of antimicrobial stewardship programs to hospital administrators. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S146-53

Newland JG, Gerber JS, Weissman SJ, et al. Prevalence and characteristics of antimicrobial stewardship programs at freestanding children's hospitals in the United States. Infect Control Hosp Epidemiol 2014 Mar;35(3):265-71

Pakyz AL, Moczygemba LR, VanderWielen LM, et al. Facilitators and barriers to implementing antimicrobial stewardship strategies: results from a qualitative study. Am J Infect Control 2014 Oct;42(10 Suppl):S257-63

Richey EA, Dudley L, Liu SK. Quality improvement in hospital management of community-acquired pneumonia: focus on new strategies and current challenges. Curr Infect Dis Rep 2014 Feb;16(2):395

Ruhnke M. Antifungal stewardship in invasive Candida infections. Clin Microbiol Infect 2014 Jun;20(Suppl 6):11-8

Smith RG, Joseph WS. Antibiotic stewardship: the lower-extremity physician's prescription for effectively treating infection. J Am Podiatr Med Assoc 2014 Jan-Feb;104(1):77-84

Tamma PD, Holmes A, Ashley ED. Antimicrobial stewardship: another focus for patient safety? Curr Opin Infect Dis 2014 Aug;27(4):348-55

Thern J, de With K, Strauss R, et al. Selection of hospital antimicrobial prescribing quality indicators: a consensus among German antibiotic stewardship (ABS) networkers. Infection 2014 Apr;42(2):351-62

Tonna AP, Gould IM, Stewart D. A cross-sectional survey of antimicrobial stewardship strategies in UK hospitals. J Clin Pharm Ther 2014 Oct;39(5):516-20

Trivedi KK, Dumartin C, Gilchrist M. Identifying best practices across three countries: hospital antimicrobial stewardship in the United Kingdom, France, and the United States. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S170-8

Trivedi KK, Kuper K. Hospital antimicrobial stewardship in the nonuniversity setting. Infect Dis Clin North Am 2014 Jun;28(2):281-9

Trivedi KK, Pollack LA. The role of public health in antimicrobial stewardship in healthcare. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S101-3

Trivedi KK, Kuper K. Hospital antimicrobial stewardship in the nonuniversity setting. Infect Dis Clin North Am 2014 Jun;28(2):281-9

Trivedi KK, Pollack LA. The role of public health in antimicrobial stewardship in healthcare. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S101-3

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2013

Abbo LM, et al. Medical students' perceptions and knowledge about antimicrobial stewardship: how are we educating our future prescribers? Clin Infect Dis 2013 Sep;57(5):631-8

Almirante B, et al. Scientific evidence and research in antimicrobial stewardship. Enferm Infecc Microbiol Clin 2013 Sep;31(Suppl 4):56-61

Bartlett JG, et al. Seven ways to preserve the miracle of antibiotics. Clin Infect Dis 2013;56:1445-50

Bowen M, et al. Call for antimicrobial stewardship policy. J Am Vet Med Assoc 2013 Dec 15;243(12):1675

Davis SL, et al. Adherence to the 2009 consensus guidelines for vancomycin dosing and monitoring practices: a cross-sectional survey of U.S. hospitals. Pharmacotherapy 2013 Dec;33(12):1256-63

Duane TM, et al. Surgeons do not listen: evaluation of compliance with antimicrobial stewardship program recommendations. Am Surg 2013 Dec;79(12):1269-72

Earnshaw S, et al. Global collaboration to encourage prudent antibiotic use. Lancet Infect Dis 2013 Dec;13(12):1003-4

FDA. Antibacterial Drug Development Task Force.

Gillespie E, et al. Improving antibiotic stewardship by involving nurses. Am J Infect Control 2013;41:365-7

Goncalves-Pereira J, et al. Cooperative approach: a further step in antimicrobial stewardship programs. Crit Care Med 2013 Sep;41(9):2226-7

Hadley S, et al. Antimicrobial stewardship: impact and challenges. Clin Ther 2013 Jun;35(6):748-50

Huang DT, et al. Antibiotic stewardship — what should I do tomorrow? Ann Emerg Med 2013 Jul;62(1):78-9

Hurst JM, Bosso JA. Antimicrobial stewardship in the management of community-acquired pneumonia. Curr Opin Infect Dis 2013;26:184-8

Hyun DY, et al. Antimicrobial stewardship in pediatrics: how every pediatrician can be a steward. JAMA Pediatr 2013 Sep;167(9):859-66

Ladenheim D, et al. Antimicrobial stewardship: the role of the nurse. Nurs Stand 2013 Oct 9- 15;28(6):46-9

Leuthner KD, et al. Antimicrobial stewardship programs. J Clin Microbiol 2013 Dec;51(12):3916-20

Lopez-Medrano F, et al. How to assist clinicians in improving antimicrobial prescribing: tools and interventions provided by stewardship programs. Enferm Infecc Microbiol Clin 2013 Sep;31(Suppl 4):38-44

Luther VP, et al. Antimicrobial stewardship education for medical students. Clin Infect Dis 2013 Nov;57(9):1366

May L, et al. A call to action for antimicrobial stewardship in the emergency department: approaches and strategies. Ann Emerg Med 2013 Jul;62(1):69-77.e2

Muldoon EG, et al. Are we ready for an outpatient parenteral antimicrobial therapy bundle? A critical appraisal of the evidence. Clin Infect Dis 2013 Aug;57(3):419-24

Murni I, et al. Prevention of nosocomial infections in developing countries, a systematic review. Paediatr Int Child Health 2013 May;33(2):61-78

O'Brien DJ, et al. Maximizing the impact of antimicrobial stewardship: the role of diagnostics, national and international efforts. Curr Opin Infect Dis 2013 Aug;26(4):352-8

Pollack LA, et al. In not now, when? Seizing the moment for antibiotic stewardship. Infect Control Hosp Epidemiol 2013 Feb;34(2):117-8

Pulcini C, Gyssens IC. How to educate prescribers in antimicrobial stewardship practices. Virulence 2013;4:192-202

Rello J, et al. Antibiotic stewardship in hospital-acquired pneumonia. Chest 2013 May;143(5):1195-6

Rimawi RH, et al. Impact of regular collaboration between infectious diseases and critical care practitioners on antimicrobial utilization and patient outcome. Crit Care Med 2013 Sep;41(9):2099-107

Rex JH, et al. A comprehensive regulatory framework to address the unmet need for new antibacterial treatments. Lancet Infect Dis 2013;13:269-75

Trivedi KK, Rosenberg J. The state of antimicrobial stewardship programs in California. Infect Control Hosp Epidemiol 2013;34:379-84

Wertheim HF, et al. Providing impetus, tools, and guidance to strengthen national capacity for antimicrobial stewardship in Viet Nam. PLoS Med 2013;10(5):e1001429

Wickens HJ, et al. The increasing role of pharmacists in antimicrobial stewardship in English hospitals. J Antimicrob Chemother 2013 Nov;68(11):2675-81

Wilde AM, et al. A new practitioner's guide to antimicrobial stewardship. Am J Health Syst Pharm 2013 Dec 15;70(24):2180, 2182-3

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2012

Coll A, et al. Design of antimicrobial stewardship care bundles on the high dependency unit. Int J Clin Pharm 2012;34:845-54

Goff DA, et al. Is the "low-hanging fruit" worth picking for antimicrobial stewardship programs? Clin Infect Dis 2012;55:587-92

Griffith M, et al. Antimicrobial stewardship programs: methods of operation and suggested outcomes. Expert Rev Anti Infect Ther 2012;10:63-73

Ikai H, et al. Impact of postgraduate education on physician practice for community-acquired pneumonia. J Eval Clin Pract 2012;18:389-95

McNulty CA, et al. Education of healthcare professionals and the public. J Antimicrob Chemother 2012;67(Suppl 1):i11-8

Morgan DJ, et al. Does nonpayment for hospital-acquired catheter-associated urinary tract infections lead to overtesting and increased antimicrobial prescribing? Clin Infect Dis 2012 Oct;55(7):923-9

Nathwani D, et al. Antimicrobial stewardship in Scotland: impact of a national programme. Antimicrob Resist Infect Control 2012 Feb 3;1(1):7

Shrestha NK, et al. Antimicrobial stewardship at transition of care from hospital to community. Infect Control Hosp Epidemiol 2012 Apr;33(4):401-4

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2011

Acquisto NM, et al. Antimicrobial stewardship in the emergency department. J Pharm Pract 2011 Apr;24(2):196-202

Altunsoy A, et al. The impact of a nationwide antibiotic restriction program on antibiotic usage and resistance against nosocomial pathogens in Turkey. Int J Med Sci 2011;8:339-44

Bartlett JG. A call to arms: the imperative for antimicrobial stewardship. Clin Infect Dis 2011 Aug;53 Suppl1:S4-7

Bevilacqua S, et al. 15 years of antibiotic stewardship policy in the Nancy Teaching Hospital. Med Mal Infect 2011;41:532-9

Evans CT, et al. Knowledge and use of antimicrobial stewardship resources by spinal cord injury providers. PM R 2011;3:619-23

Goff Da. Antimicrobial stewardship: bridging the gap between quality care and cost. Curr Opin Infect Dis 2011 Feb;24 Suppl 1:S11-20

Johannsson B, et al. Improving antimicrobial stewardship: the evolution of programmatic strategies and barriers. Infect Control Hosp Epidemiol 2011;32:367-74

Kesselheim AS, Outterson K. Improving antibiotic markets for long term sustainability. Yale Journal of Health Policy, Law ,and Ethics. 2011

Leung V, et al. Growing a "positive culture" of antimicrobial stewardship in a community hospital. Can J Hosp Pharm 2011;64:314-20

Levy-Hara G, et al. "Ten Commandments" for the Appropriate use of Antibiotics by the Practicing Physician in an Outpatient Setting. Front Microbiol 2011;2:230

Nathwani D, et al. Scottish Antimicrobial Prescribing Group (SAPG): development and impact of the Scottish National Antimicrobial Stewardship Programme. Int J Antimicrob Agents 2011;38:16-26

Ohl CA, Luther VP. Antimicrobial stewardship for inpatient facilities. J Hosp Med 2011;6(suppl 1):S4-15

Palmer HR, et al. Improving patient care through implementation of an antimicrobial stewardship program. Am J Health Syst Pharm 2011;68:2170-4

Spellberg B. The antibiotic crisis: can we reverse 65 years of failed stewardship? Arch Intern Med 2011 Jun 27;171(12):1080-1

Srinivasan A. Engaging hospitalists in antimicrobial stewardship: the CDC perspective. J Hosp Med 2011 Jan;6 Suppl1:S31-3

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2010

Gandhi TN, et al. Managing antimicrobial resistance in intensive care units. Crit Care Med 2010;38:S315-23

Morris AM, et al. Establishing an antimicrobial stewardship program. Healthc Q 2010;13:64-70

Njoku JC, Hermsen ED. Antimicrobial stewardship in the intensive care unit: a focus on potential pitfalls. J Pharm Pract 2010;23:50-60

Toth NR, et al. Implementation of a care bundle for antimicrobial stewardship. Am J Health Syst Pharm 2010;67:746-9

Yang Y, et al. Hospital policies and practices on prevention and treatment of infections caused by methicillin-resistant Staphylococcus aureus. Am J Health Syst Pharm 2010;67:1017-24

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Stewardship: Interventions

(Pre-authorization and/or prospective audit with feedback, education, facility-specific guidelines for common infectious disease syndromes, interventions for patients with specific infectious disease syndromes, CDI risk reduction, prescriber-led review [eg, antibiotic stop orders, antibiotic timeouts], computerized clinical support systems, antibiotic cycling)

2016
2015
2014
2013
2012
2011
2010

2016

Avent ML, Hansen MP, Gilks C, et al. General practitioner antimicrobial stewardship programme study (GAPS): protocol for a cluster randomised controlled trial. BMC Fam Pract 2016 Apr 21;17:48

Beaudoin M, Kabanza F, Nault V, et al. Evaluation of a machine learning capability for a clinical decision support system to enhance antimicrobial stewardship programs. Artif Intell Med 2016 Mar;68:29-36

Beaulac K, Corcione S, Epstein L, et al. Antimicrobial stewardship in a long-term acute care hospital using offsite electronic medical record audit. Infect Control Hosp Epidemiol 2016 Apr;37(4):433-9

Bhalla N, Hussein N, Atari M, et al. Introducing an antibiotic stewardship program in a humanitarian surgical hospital. Am J Infect Control 2016 (published online May 17)

Boel J, Andreasen V, Jarlov JO, et al. Impact of antibiotic restriction on resistance levels of Escherichia coli: a controlled interrupted time series study of a hospital-wide antibiotic stewardship programme. J Antimicrob Chemother 2016 Jul;71(7):2047-51

Bond SE, Boutlis CS, Jansen SG, et al. Discontinuation of peri-operative gentamicin use for indwelling urinary catheter manipulation in orthopaedic surgery. ANZ J Surg 2016 (published online Jun 3)

Borde JP, Nussbaum S, Hauser S, et al. Implementing an intensified antibiotic stewardship programme targeting daptomycin use in orthopaedic surgery: a cost-benefit analysis from the hospital perspective. Infection 2016 Jun;44(3):301-7

Brink AJ, Messina AP, Feldman C, et al. Antimicrobial stewardship across 47 South African hospitals: an implementation study. Lancet Infect Dis 2016 (published online Jun 13)

Broom J, Broom A, Plage S, et al. Barriers to uptake of antimicrobial advice in a UK hospital: a qualitative study. J Hosp Infect 2016 (published online Mar 26)

Brumley PE, Malani AN, Kabara JJ, et al. Effect of an antimicrobial stewardship bundle for patients with Clostridium difficile infection. J Antimicrob Chemother 2016 Mar;71(3):836-40

Cai Y, Shek PY, Teo I, et al. A multidisciplinary antimicrobial stewardship programme safely decreases the duration of broad-spectrum antibiotic prescription in Singaporean adult renal patients. Int J Antimicrob Agents 2016 Jan;47(1):91-6

Cai T, Verze P, Brugnolli A, et al. Adherence to European Association of Urology guidelines on prophylactic antibiotics: an important step in antimicrobial stewardship. Eur Urol 2016 Feb;69(2):276-83

Cheng CY, Lee CY, Wu MW, et al. Prospective antimicrobial audit and feedback did not decrease case fatality: experiences from a hospital in northern Taiwan. J Infect Dev Ctries 2016 Apr 28;10(4):395-9

Cheon S, Kim MJ, Yun SJ, et al. Controlling endemic multidrug-resistant Acinetobacter baumannii in intensive care units using antimicrobial stewardship and infection control. Korean J Intern Med 2016 Mar;31(2):367-74

Chow AL, Ang A, Chow CZ, et al. Implementation hurdles of an interactive, integrated, point-of-care computerised decision support system for hospital antibiotic prescription. Int J Antimicrob Agents 2016 Feb;47(2):132-9

Cresswell K, Mozaffar H, Shah S, et al. A systematic assessment of review to promoting the appropriate use of antibiotics through hospital electronic prescribing systems. Int J Pharm Pract 2016 (published online May 20)

DiDiodato G, McArthur L. Evaluating the effectiveness of an antimicrobial stewardship program on reducing the incidence rate of healthcare-associated Clostridium difficile infection: a non-randomized, stepped wedge, single-site, observational study. PLoS One 2016 Jun 16;11(6):e0157671

DiDiodato G, McArthur L, Beyene J, et al. Evaluating the impact of an antimicrobial stewardship program on the length of stay of immune-competent adult patients admitted to a hospital ward with a diagnosis of community-acquired pneumonia: a quasi-experimental study. Am J Infect Control 2016 May 1;44(5):e73-9

Frenette C, Sperlea D, Tesolin J, et al. Influence of a 5-year serial infection control and antibiotic stewardship intervention on cardiac surgical site infections. Am J Infect Control 2016 (published online Apr 25)

Garcia-Martinez L, Gracia-Ahulfinger I, Machuca I. Impact of the PROVAUR stewardship programme on linezolid resistance in a tertiary university hospital: a before-and-after interventional study. J Antimicrob Chemother 2016 (published online May 30)

Giry M, Pulcini C, Rabaud C, et al. Acceptability of antibiotic stewardship measures in primary care. Med Mal Infect 2016 (published online Apr 4)

Goldstein EJ, Goff DA, Reeve W, et al. Approaches to modifying the behavior of clinicians who are noncompliant with antimicrobial stewardship program guidelines. Clin Infect Dis 2016 (published online Apr 20)

Gong S, Qiu X, Song Y, et al. Effect of financially punished audit and feedback in a pediatric setting in China, within an antimicrobial stewardship program, and as part of an international accreditation process. Front Public Health 2016 May;4:99

Guerri-Fernandez R, Villar-Garcia J, Herrera-Fernandez S, et al. An antimicrobial stewardship program reduces antimicrobial therapy duration and hospital stay in surgical wards. Rev Esp Quimioter 2016 Jun;29(3):119-22

Hallsworth M, Chadborn T, Sallis A, et al. Provision of social norm feedback to high prescribers of antibiotics in general practice: a pragmatic national randomised controlled trial. Lancet 2016 Apr 23;387(10029):1743-52

Heath B, Bernhardt J, Michalski TJ, et al. Results of a Veterans Affairs employee education program on antimicrobial stewardship for older adults. Am J Infect Control 2016 Mar 1;44(3):349-51

Hoffmann C, Zak M, Avery L, et al. Treatment modalities and antimicrobial stewardship initiatives in the management of intra-abdominal infections. Antibiotics (Basel) 2016 Mar;5(1):11

Hogli JU, Garcia BH, Skjold F, et al. An audit and feedback intervention study increased adherence to antibiotic prescribing guidelines at a Norwegian hospital. BMC Infect Dis 2016 Feb 27;16(1):96

Huh K, Chung DR, Park HJ, et al. Impact of monitoring surgical prophylactic antibiotics and a computerized decision support system on antimicrobial use and antimicrobial resistance. Am J Infect Contro. 2016 (published online Mar 11)

Hurst AL, Child J, Pearce K, et al. Handshake stewardship: a highly effective rounding-based antimicrobial optimization service. Pediatr Infect Dis J 2016 (published online May 31)

Ironmonger D, Edeghere O, Gossain S, et al. Use of antimicrobial resistance information and prescribing guidance for management of urinary tract infections: survey of general practitioners in the West Midlands. BMC Infect Dis 2016 May 24;16(1):226

Issa N, Pedeboscq S, Le Quellec F, et al. Proper use of carbapenems: role of the infectious disease specialist. Med Mal Infect 2016 Feb;46(1):10-3 

Jones M, Butler J, Graber CJ, et al. Think twice: a cognitive perspective of an antibiotic timeout intervention to improve antibiotic use. J Biomed Inform 2016 (published online Jun 17)

Knox MC, Edye M. Educational antimicrobial stewardship intervention ineffective in changing surgical prophylactic antibiotic prescribing. Surg Infect (Larchmt) 2016 Apr;17(2):224-8

Kurtzhalts KE, Sellick JA Jr, Ruh CA, et al. Impact of antimicrobial stewardship on outcomes in hospitalized veterans with pneumonia. Clin Ther 2016 Jul;38(7):1750-8

Lai CC, Shi ZY, Chen YH, et al. Effects of various antimicrobial stewardship programs on antimicrobial usage and resistance among common gram-negative bacilli causing health care-associated infections: A multicenter comparison. J Microbiol Immunol Infect2016 Feb;49(1):74-82

Lee KR, Bagga B, Arnold SR. Reduction of broad-spectrum antimicrobial use in a tertiary children's hospital post antimicrobial stewardship program guideline implementation. Pediatr Crit Care Med 2016 Mar;17(3):187-93

Livorsi DJ, Heintz B, Jacob JT, et al. Audit and feedback processes among antimicrobial stewardship programs: a survey of the society for healthcare epidemiology of America research network. Infect Control Hosp Epidemiol 2016 Jun;37(6):704-6

Mack MR, Rohde JM, Jacobsen D, et al. Engaging hospitalists in antimicrobial stewardship: lessons from a multihospital collaborative. J Hosp Med 2016 (published online Apr 30)

Maeda M, Takuma T, Seki H, et al. Effect of interventions by an antimicrobial stewardship team on clinical course and economic outcome in patients with bloodstream infection. J Infect Chemother 2016 Feb;22(2):90-5

Meeker D, Linder JA, Fox CR, et al. Effect of behavioral interventions on inappropriate antibiotic prescribing among primary care practices: a randomized clinical trial. JAMA 2016 Feb 9;315(6):562-70

Morrill HJ, Caffrey AR, Gaitanis MM, et al. Impact of a prospective audit and feedback antimicrobial stewardship program at a veterans affairs medical center: a six-point assessment. PLoS One 2016 Mar;11(3):e0150795

Nguyen-Ha PT, Howrie D, Crowley K, et al. A quality assessment of a collaborative model of a pediatric antimicrobial stewardship program. Pediatrics 2016 Apr;137(4):e20150316

Panesar P, Jones A, Aldous A, et al. Attitudes and behaviours to antimicrobial prescribing following Introduction of a smartphone App. PLoS One 2016 Apr 25;11(4):e0154202

Pano-Pardo JR, Schuffelmann-Gutierrez C, Escosa-Garcia L, et al. Opportunities to improve antimicrobial use in paediatric intensive care units: a nationwide survey in Spain. Clin Microbiol Infect 2016 Feb;22(2):171-7

Ross RK, Beus JM, Metjian TA, et al. Safety of automatic end dates for antimicrobial orders to facilitate stewardship. Infect Control Hosp Epidemiol 2016 May 13:1-5

Sarg M, Waldrop GE, Beier MA, et al. Impact of changes in urine culture ordering practice on antimicrobial utilization in Intensive Care Units at an academic medical center. Infect Control Hosp Epidemiol 2016 Apr;37(4):448-54

Sartelli M, Labricciosa FM, Scoccia L, et al. Non-restrictive antimicrobial stewardship program in a general and emergency surgery unit. Surg Infect (Larchmt) 2016 (published online May )

Shafiq N, Praveen Kumar M, Gautam V, et al. Antibiotic stewardship in a tertiary care hospital of a developing country: establishment of a system and its application in a unit-GASP Initiative. Infection 2016 (published online Jun 20)

Sikkens JJ, van Agtmael MA, Peters EJ, et al. Assessment of appropriate antimicrobial prescribing: do experts agree? J Antimicrob Chemother 2016 (published online Jun 10)

Tagashira Y, Horiuchi M, Tokuda Y, et al. Antimicrobial stewardship for carbapenem use at a Japanese tertiary care center: An interrupted time series analysis on the impact of infectious disease consultation, prospective audit, and feedback. Am J Infect Control 2016 Jun 1;44(6):708-10

Van Hollebeke M, Chapuis C, Bernard S, et al. Compliance with carbapenem guidelines in a university hospital. Med Mal Infect 2016 Mar;46(2):72-8

Wentzel J, van Drie-Pierik R, Nijdam L, et al. Antibiotic information application offers nurses quick support. Am J Infect Control 2016 Jun 1;44(6):677-84

Yeo JM. Antimicrobial stewardship: improving antibiotic prescribing practice in a respiratory ward. BMJ Qual Improv Rep 2016 Jul;5(1)

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2015

Anthierens S, Tonkin-Crine S, Cals JW, et al. Clinicians' views and experiences of interventions to enhance the quality of antibiotic prescribing for acute respiratory tract infections. J Gen Intern Med 2015 Apr;30(4):408-16

Arena F, Scolletta S, Marchetti L, et al. Impact of a clinical microbiology-intensive care consulting program in a cardiothoracic intensive care unit. Am J Infect Control 2015 (published online Jun 3)

Bessesen MT, Ma A, Clegg D, et al. Antimicrobial stewardship programs: comparison of a program with infectious diseases pharmacist support to a program with a geographic pharmacist staffing model. Hosp Pharm 2015 Jun;50(6):477-83

Borde JP, Kern WV, Hug M, et al. Implementation of an intensified antibiotic stewardship programme targeting third-generation cephalosporin and fluoroquinolone use in an emergency medicine department. Emerg Med J 2015 Jul;32(7):509-15

Borde JP, Litterst S, Ruhnke M, et al. Implementing an intensified antibiotic stewardship programme targeting cephalosporin and fluoroquinolone use in a 200-bed community hospital in Germany. Infection 2015 Feb;43(1):45-50

Carreno JJ, Kenney RM, Bloome M, et al. Evaluation of pharmacy generalists performing antimicrobial stewardship services. Am J Health Syst Pharm 2015 Aug 1;72(15):1298-303

Chan S, Hossain J, Di Pentima MC. Implications and impact of prior authorization policy on vancomycin use at a tertiary pediatric teaching hospital. Pediatr Infect Dis J 2015 May;34(5):506-8

Chow AL, Ang A, Chow CZ, et al. Implementation hurdles of an interactive, integrated, point-of-care computerised decision support system for hospital antibiotic prescription. Int J Antimicrob Agents 2015 (published online Dec 28)

Chow A, Lye DC, Arah OA. Psychosocial determinants of physicians' acceptance of recommendations by antibiotic computerised decision support systems: a mixed methods study. Int J Antimicrob Agents 2015 Mar;45(3):295-304

Cook PP, Gooch M. Long-term effects of an antimicrobial stewardship programme at a tertiary-care teaching hospital. Int J Antimicrob Agents 2015 Mar;45(3):262-7

Cotta MO, Robertson MS, Marshall C, et al. Implementing antimicrobial stewardship in the Australian private hospital system: a qualitative study. Aust Health Rev 2015 Jun;39(3):315-22

Daneman N, Guttmann A, Wang X, et al. The association of hospital prevention processes and patient risk factors with the risk of Clostridium difficile infection: a population-based cohort study. BMJ Qual Saf 2015 Jul;24(7):435-43

Day SR, Smith D, Harris K, et al. An infectious diseases physician-led antimicrobial stewardship program at a small community hospital associated with improved susceptibility patterns and cost-savings after the first year. Open Forum Infect Dis 2015 May 12;2(2):ofv064

DiDiodato G, McArthur L, Beyene J, et al. Can an antimicrobial stewardship program reduce length of stay of immune-competent adult patients admitted to hospital with diagnosis of community-acquired pneumonia? Study protocol for pragmatic controlled non-randomized clinical study. Trials 2015 Aug 14;16:355

Dik JW, Hendrix R, Friedrich AW, et al. Cost-minimization model of a multidisciplinary antibiotic stewardship team based on a successful implementation on a urology ward of an academic hospital. PLoS One 2015 May 8;10(5):e0126106

Dik JW, Hendrix R, Lo-Ten-Foe JR, et al. Automatic day-2 intervention by a multidisciplinary antimicrobial stewardship-team leads to multiple positive effects. Front Microbiol 2015 Jun 3;6:546

Evans RS, Olson JA, Stenehjem E, et al. Use of computer decision support in an antimicrobial stewardship program (ASP). Appl Clin Inform 2015 Mar 3;6(1):120-35

Gauthier TP, Sherman EM, Unger NR. An elective course on antimicrobial stewardship. Am J Pharm Educ 2015 Dec 25;79(10):157

Goldman JL, Lee BR, Hersh AL, et al. Clinical diagnoses and antimicrobials predictive of pediatric antimicrobial stewardship recommendations: a program evaluation. Infect Control Hosp Epidemiol 2015 Jun;36(6):673-80

Hall AB, Montero J, Cobian J, et al. The effects of an electronic order set on vancomycin dosing in the ED. Am J Emerg Med 2015 Jan;33(1):92-4

Hamilton KW, Gerber JS, Moehring R, et al. Point-of-prescription interventions to improve antimicrobial stewardship. Clin Infect Dis 2015 Apr 15;60(8):1252-8

Hernandez-Santiago V, Marwick CA, Patton A, et al. Time series analysis of the impact of an intervention in Tayside, Scotland to reduce primary care broad-spectrum antimicrobial use. J Antimicrob Chemother 2015 Aug;70(8):2397-404

Hingorani R, Mahmood M, Alweis R. Improving antibiotic adherence in treatment of acute upper respiratory infections: a quality improvement process. J Community Hosp Intern Med Perspect 2015 Jun 15;5(3):27472

Kamata K, Suzuki H, Kanemoto K, et al. Clinical evaluation of the need for carbapenems to treat community-acquired and healthcare-associated pneumonia. J Infect Chemother 2015 Aug;21(8):596-603

Kram JJ, Borlaug G, Safdar N, et al. Development and distribution of educational materials for carbapenem-resistant Enterobacteriaceae among acute and long-term care facilities. WMJ 2015 Apr;114(2):48-51

Lai CC, Shi ZY, Chen YH, et al. Effects of various antimicrobial stewardship programs on antimicrobial usage and resistance among common gram-negative bacilli causing health care-associated infections: a multicenter comparison. J Microbiol Immunol Infect 2015 (published online Nov 12)

Lawes T, Lopez-Lozano JM, Nebot CA, et al. Effects of national antibiotic stewardship and infection control strategies on hospital-associated and community-associated methicillin-resistant Staphylococcus aureus infections across a region of Scotland: a non-linear time-series study. Lancet Infect Dis 2015 Dec;15(12):1438-49

Lawes T, Lopez-Lozano JM, Nebot C, et al. Turning the tide or riding the waves? Impacts of antibiotic stewardship and infection control on MRSA strain dynamics in a Scottish region over 16 years: non-linear time series analysis. BMJ Open 2015 Mar 26;5(3):e006596

Llewelyn MJ, Hand K, Hopkins S, et al. Antibiotic policies in acute English NHS trusts: implementation of 'Start Smart-Then Focus' and relationship with Clostridium difficile infection rates. J Antimicrob Chemother 2015 Apr;70(4):1230-5

Lesprit P, de Pontfarcy A, Esposito-Farese M, et al. Postprescription review improves in-hospital antibiotic use: a multicenter randomized controlled trial. Clin Microbiol Infect 2015 Feb;21(2):180.e1,180.e7

Liew YX, Lee W, Tay D, et al. Prospective audit and feedback in antimicrobial stewardship: is there value in early reviewing within 48 h of antibiotic prescription? Int J Antimicrob Agents 2015 Feb;45(2):168-73

McCulloh RJ, Queen MA, Lee B, et al. Clinical impact of an antimicrobial stewardship program on pediatric hospitalist practice, a 5-year retrospective analysis. Hosp Pediatr 2015 Oct;5(10):520-7

Mertz D, Brooks A, Irfan N, et al. Antimicrobial stewardship in the intensive care setting--a review and critical appraisal of the literature. Swiss Med Wkly 2015 Dec 21;145:w14220

Messina AP, van den Bergh D, Goff DA. Antimicrobial stewardship with pharmacist intervention improves timeliness of antimicrobials across thirty-three hospitals in South Africa. Infect Dis Ther 2015 Sep;4(Suppl 1):5-14

Micallef C, Aliyu SH, Santos R, et al. Introduction of an antifungal stewardship programme targeting high-cost antifungals at a tertiary hospital in Cambridge, England. J Antimicrob Chemother 2015;70(6):1908-11

Morquin D, Ologeanu-Taddei R, Koumar Y, et al. Implementing a tele-expertise system to optimise the antibiotic use and stewardship: the case of the Montpellier University Hospital (France). Stud Health Technol Inform 2015;210:296-300

Murni IK, Duke T, Kinney S, et al. Reducing hospital-acquired infections and improving the rational use of antibiotics in a developing country: an effectiveness study. Arch Dis Child 2015 May;100(5):454-9

Nguyen CT, Gandhi T, Chenoweth C, et al. Impact of an antimicrobial stewardship-led intervention for Staphylococcus aureus bacteraemia: a quasi-experimental study. J Antimicrob Chemother 2015 Dec;70(12):3390-6

Nilholm H, Holmstrand L, Ahl J, et al. An audit-based, infectious disease specialist-guided antimicrobial stewardship program profoundly reduced antibiotic use without negatively affecting patient outcomes. Open Forum Infect Dis 2015 Mar 23;2(2):ofv042

Okumura LM, Silva MM, Veroneze I. Effects of a bundled antimicrobial stewardship program on mortality: a cohort study. Braz J Infect Dis 2015 May-Jun;19(3):246-52

Percival KM, Valenti KM, Schmittling SE, et al. Impact of an antimicrobial stewardship intervention on urinary tract infection treatment in the ED. Am J Emerg Med 2015 Sep;33(9):1129-33

Popovski Z, Mercuri M, Main C, et al. Multifaceted intervention to optimize antibiotic use for intra-abdominal infections. J Antimicrob Chemother 2015 Apr;70(4):1226-9

Powell N, Franklin BD, Jacklin A, et al. Omitted doses as an unintended consequence of a hospital restricted antibacterial system: a retrospective observational study. J Antimicrob Chemother 2015 Dec;70(12):3379-83

Rocha-Pereira N, Lafferty N, Nathwani D. Educating healthcare professionals in antimicrobial stewardship: can online-learning solutions help? J Antimicrob Chemother 2015 Dec;70(12):3175-7

Roberts E, Dawoud DM, Hughes DA, et al. Evaluation of a consultant audit and feedback programme to improve the quality of antimicrobial prescribing in acute medical admissions. Int J Pharm Pract 2015 Oct;23(5):333-9

Saied T, Hafez SF, Kandeel A, et al. Antimicrobial stewardship to optimize the use of antimicrobials for surgical prophylaxis in Egypt: a multicenter pilot intervention study. Am J Infect Control 2015 Nov 1;43(11):e67-71

Sarma JB, Marshall B, Cleeve V, et al. Effects of fluoroquinolone restriction (from 2007 to 2012) on Clostridium difficile infections: Interrupted time-series analysis. J Hosp Infect 2015 Sep;91(1):74-80

Sneddon J, Gilchrist M, Wickens H. Development of an expert professional curriculum for antimicrobial pharmacists in the UK. J Antimicrob Chemother 2015 May;70(5):1277-80

Song YJ, Kim M, Huh S, et al. Impact of an antimicrobial stewardship on unnecessary double anaerobic coverage prescription. Infect Chemother 2015 Jun;47(2):111-6

Taggart LR, Leung E, Muller MP, et al. Differential outcome of an antimicrobial stewardship audit and feedback program in two intensive care units: a controlled interrupted time series study. BMC Infect Dis 2015 Oct 29;15:480

Teng CB, Ng TM, Tan MW, et al. Safety and effectiveness of improving carbapenem use via prospective review and feedback in a multidisciplinary antimicrobial stewardship programme. Ann Acad Med Singapore 2015 Jan;44(1):19-25

Trautner BW, Grigoryan L, Petersen NJ, et al. Effectiveness of an antimicrobial stewardship approach for urinary catheter-associated asymptomatic bacteriuria. JAMA Intern Med 2015 Jul;175(7):1120-7

Velez RP, Becker KL, Davidson P, et al. A quality improvement intervention to address provider behaviour as it relates to utilisation of CA-MRSA guidelines. J Clin Nurs 2015 Feb;24(3-4):556-62

Waters CD. Pharmacist-driven antimicrobial stewardship program in an institution without infectious diseases physician support. Am J Health Syst Pharm 2015 Mar 15;72(6):466-8

Wattal C, Goel N, Khanna S, et al. Impact of informational feedback to clinicians on antibiotic-prescribing rates in a tertiary care hospital in Delhi. Indian J Med Microbiol 2015 Apr-Jun;33(2):255-9

Wood ZH, Nicolsen NC, Allen N, et al. Remote antimicrobial stewardship in community hospitals. Antibiotics (Basel) 2015 Nov 13;4(4):605-16

Zhou Y, Ma LY, Zhao X, et al. Impact of pharmacist intervention on antibiotic use and prophylactic antibiotic use in urology clean operations. J Clin Pharm Ther 2015 Aug;40(4):404-8

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2014

Aldeyab MA, Scott MG, Kearney MP, et al. Impact of an enhanced antibiotic stewardship on reducing methicillin-resistant Staphylococcus aureus in primary and secondary healthcare settings. Epidemiol Infect 2014 Mar;142(3):494-500

Alfandari S, Berthon C, Coiteaux V. Antifungal stewardship: implementation in a French teaching hospital. Med Mal Infect 2014 Apr;44(4):154-8

Asakura T, Ikeda M, Nakamura A, et al. Efficacy of empirical therapy with non-carbapenems for urinary tract infections with extended-spectrum beta-lactamase-producing Enterobacteriaceae. Int J Infect Dis 2014 Dec;29:91-5

Benson JM. Incorporating pharmacy student activities into an antimicrobial stewardship program in a long-term acute care hospital. Am J Health Syst Pharm 2014 Feb 1;71(3):227-30

Borde JP, Batin N, Rieg S. Adherence to an antibiotic stewardship bundle targeting Staphylococcus aureus blood stream infections at a 200-bed community hospital. Infection 2014 Aug;42(4):713-9

Borde JP, Kaier K, Steib Bauert M, et al. Feasibility and impact of an intensified antibiotic stewardship programme targeting cephalosporin and fluoroquinolone use in a tertiary care university medical center. BMC Infect Dis 2014 Apr 15;14:201

Buyle FM, Wallaert M, Beck N, et al. Implementation of a multidisciplinary infectious diseases team in a tertiary hospital within an antimicrobial stewardship program. Acta Clin Belg 2014 Oct;69(5):320-6

Chaves NJ, Ingram RJ, MacIsaac CM, et al. Sticking to minimum standards: implementing antibiotic stewardship in intensive care. Intern Med J 2014 Dec;44(12a):1180-7

Cisneros JM, Neth O, Gil Navarro MV, et al. Global impact of an educational antimicrobial stewardship programme on prescribing practice in a tertiary hospital centre. Clin Microbiol Infect 2014 Jan;20(1):82-8

Conant MM, Erdman SM, Osterholzer D. Mandatory infectious diseases approval of outpatient parenteral antimicrobial therapy (OPAT): clinical and economic outcomes of averted cases. J Antimicrob Chemother 2014 Jun;69(6):1695-700

De Bus L, Saerens L, Gadeyne B, et al. Development of antibiotic treatment algorithms based on local ecology and respiratory surveillance cultures to restrict the use of broad-spectrum antimicrobial drugs in the treatment of hospital-acquired pneumonia in the intensive care unit: a retrospective analysis. Crit Care 2014 Jul 14;18(4):R152

Demonchy E, Dufour JC, Gaudart J, et al. Impact of a computerized decision support system on compliance with guidelines on antibiotics prescribed for urinary tract infections in emergency departments: a multicentre prospective before-and-after controlled interventional study. J Antimicrob Chemother 2014 Oct;69(10):2857-63

Durnkow LE, Kenney RM, MacDonald NC, et al. Impact of a multidisciplinary culture follow-up program of antimicrobial therapy in the emergency department. Infect Dis Ther 2014 Jun;3(1):45-53

Elemraid MA, Rushton SP, Thomas MF, et al. Changing clinical practice: management of paediatric community-acquired pneumonia. J Eval Clin pract 2014 Feb;20(1):94-9

Forrest GN, Van Schooneveld TC, Kullar R, et al. Use of electronic health records and clinical decision support systems for antimicrobial stewardship. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S122-33

Hadjiphilippou S, Odogwu SE, Jeyaratnam D. Promoting antimicrobial stewardship: using video tools for junior doctors' induction. Br J Hosp Med (Lond) 2014 Feb;75(2):106-8

Halpape K, Sulz L, Schuster B, et al. Audit and feedback-focused approach to evidence-based care in treating patients with pneumonia in hospital (AFFECT study). Can J Hosp Pharm 2014 Jan;67(1):17-27

Hecker MT, Fox CJ, Son AH, et al. Effect of a stewardship intervention on adherence to uncomplicated cystitis and pyelonephritis guidelines in an emergency department setting. PLoS One 2014 Feb 3;9(2):e87899

Hou D, Wang Q, Jiang C, et al. Evaluation of the short-term effects of antimicrobial stewardship in the intensive care unit at a tertiary hospital in China. PLoS One 2014 Jul 7;9(7):e101447

Kelley D, Aaronson P, Poon E, et al. Evaluation of an antimicrobial stewardship approach to minimize overuse of antibiotics in patients with asymptomatic bacteriuria. Infect Control Hosp Epidemiol 2014 Feb;35(2):193-5

Knudsen JD, Andersen SE, Bispebjerg Intervention Group. A multidisciplinary intervention to reduce infections of ESBL- and AmpC-producing, gram-negative bacteria at a university hospital. PLoS One 2014 Jan 23;9(1):e86457

Kullar R, Goff DA. Transformation of antimicrobial stewardship programs through technology and informatics. Infect Dis Clin North Am 2014 Jun;28(2):291-300

Lee TC, Frenette C, Jayaraman D, et al. Antibiotic self-stewardship: trainee-led structured antibiotic time-outs to improve antimicrobial use. Ann Intern Med 2014 Nov 18;161(10 Suppl):S53-8

Mehta JM, Haynes K, Wileyto EP, et al. Comparison of prior authorization and prospective audit with feedback for antimicrobial stewardship. Infect Control Hosp Epidemiol 2014 Sep;35(9):1092-9

Meng P, Fehre K, Rappelsberger A, et al. Mobile display of information about aggregated antibiotic resistance in the hospital setting supported by near field communication. Stud Health Technol Inform 2014;200:88-92

Morquin D, Koumar Y, Ologeanu Taddei R, et al. Integrating electronic medical records to improve antimicrobial stewardship at the Montpellier Hospital in France. World Hosp Health Serv 2014;50(2):35-9

Morrill HJ, Gaitanis MM, LaPlante KL. Antimicrobial stewardship program prompts increased and earlier infectious diseases consultation. Antimicrob Resist Infect Control 2014 Apr 17;3:12

Nachtigall I, Tafelski S, Deja M, et al. Long-term effect of computer-assisted decision support for antibiotic treatment in critically ill patients: a prospective 'before/after' cohort study. BMJ Open 2014 Dec 22;4(12):e005370

Ohl CA, Luther VP. Health care provider education as a tool to enhance antibiotic stewardship practices. Infect Dis Clin North Am 2014 Jun;28(2):177-93

Ostrowsky B, Ruiz R, Brown S, et al. Lessons learned from implementing Clostridium difficile-focused antibiotic stewardship interventions. Infect Control Hosp Epidemiol 2014 Oct;35(Suppl 3):S86-95

Ou Y, Jing BQ, Guo FF, et al. Audits of the quality of perioperative antibiotic prophylaxis in Shandong Province, China, 2006 to 2011. Am J Infect Control 2014 May;42(5):516-20

Palmay L, Elligsen M, Walker SA, et al. Hospital-wide rollout of antimicrobial stewardship: a stepped-wedge randomized trial. Clin Infect Dis 2014 Sep 15;59(6):867-74

Pasquale TR, Trienski TL, Olexia DE, et al. Impact of an antimicrobial stewardship program on patients with acute bacterial skin and skin structure infections. Am J Health Syst Pharm 2014 Jul 1;71(13):1136-9

Pogue JM, Mynatt RP, Marchaim D, et al. Automated alerts coupled with antimicrobial stewardship intervention lead to decreases in length of stay in patients with gram-negative bacteremia. Infect Control Hosp Epidemiol 2014 Feb;35(2):132-8

Pogue JM, Potoski BA, Postelnick M, et al. Bringing the "power" to Cerner's PowerChart for antimicrobial stewardship. Clin Infect Dis 2014 Aug 1;59(3):416-24

Ramos A, Benitez Gutierrez L, Asensio A, et al. Antimicrobial stewardship in patients recently transferred to a ward from the ICU. Rev Esp Quimioter 2014 Mar;27(1):46-50

Reed EE, West JE, Keating EA, et al. Improving the management of candidemia through antimicrobial stewardship interventions. Diagn Microbiol Infect Dis 2014 Feb;78(2):157-61

Rodriguez L, Jung, HS, Goulet JA, et al. Evidence-based protocol for prophylactic antibiotics in open fractures: improved antibiotic stewardship with no increase in infection rates. J Trauma Acute Care Surg 2014 Sep;77(3):400-7

Seah XF, Ong YL, Tan SW, et al. Impact of an antimicrobial stewardship program on the use of carbapenems in a tertiary women's and children's hospital, Singapore. Pharmacotherapy 2014 Nov;34(11):1141-50

Smith T, Philmon CL, Johnson GD, et al. Antimicrobial stewardship in a community hospital: attacking the more difficult problems. Hosp Pharm 2014 Oct;49(9):839-46

Song P, Li W, Zhou Q. An outpatient antibacterial stewardship intervention during the journey to JCI accreditation. BMC Pharmacol Toxicol 2014 Feb 26;15:8

Spellberg B. Antibiotic judo: working gently with prescriber psychology to overcome inappropriate use. JAMA Intern Med 2014 Mar;174(3):432-3

Szymczak JE, Feemster KA, Zaoutis TE, et al. Pediatrician perceptions of an outpatient antimicrobial stewardship intervention. Infect Control Hosp Epidemiol 2014 Oct;35(Suppl 3):S69-78

Van Buul LW, Sikkens JJ, van Agtmael MA, et al. Participatory action research in antimicrobial stewardship: a novel approach to improving antimicrobial prescribing in hospitals and long-term care facilities. J Antimicrob Chemother 2014 Jul;69(7):1734-41

Van Dujin PJ, Bonten MJ. Antibiotic rotation strategies to reduce antimicrobial resistance in gram-negative bacteria in European intensive care units: study protocol for a cluster-randomized crossover controlled trial. Trials 2014 Jul 10;15:277

Van Limburg M, Sinha B, Lo Ten Foe JR, et al. Evaluation of early implementations of antibiotic stewardship program initiatives in nine Dutch hospitals. Antimicrob Resist Infect Control 2014 Oct 23;3(1):33

Venugopal V, Lehmann CU, Diener West M. Longitudinal evaluation of a World Wide Web-based antimicrobial stewardship program: assessing factors associated with approval patterns and trends over time. Am J Infect Control 2014 Feb;42(2):100-5

Wagner B, Filice GA, Drekonja D, et al. Antimicrobial stewardship programs in inpatient hospital settings: a systematic review. Infect Control Hosp Epidemiol 2014 Oct;35(10):1209-28

Wentzel J, van Velsen L, van Limburg M, et al. Participatory eHealth development to support nurses in antimicrobial stewardship. BMC Med Inform Decis Mak 2014 Jun 5;14:45

Yoon YK, Yang KS, Lee SE, et al. Effects of Group 1 versus Group 2 carbapenems on the susceptibility of Acinetobacter baumannii to carbapenems: a before and after intervention study of carbapenem-use stewardship. PLoS One 2014 Jun 9;9(6):e99101

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2013

Ambroggio L, et al. Quality improvement methods increase appropriate antibiotic prescribing for childhood pneumonia. Pediatrics 2013 May;131(5):e1623-31

Amer MR, et al. Antimicrobial stewardship program implementation in a medical intensive care unit at a tertiary care hospital in Saudi Arabia. Ann Saudi Med 2013 Nov-Dec;33(6):547-54

Andersen SE, et al. A managed multidisciplinary programme on multi-resistant Klebsiella pneumoniae in a Danish university hospital. BMJ Qual Saf 2013 Nov;22(11):907-15

Baysari MT, et al. Audit and feedback of antibiotic use: utilising electronic prescription data. Appl Clin Inform 2013 Dec 11;4(4):583-95

Cairns KA, et al. Prescribing trends before and after implementation of an antimicrobial stewardship program. Med J Aust 2013;198:262-6

Camargo LF. The "de-escalation concept" and antibiotic de-escalation: a missed opportunity? Shock 2013;39(7 suppl 1):29-31

Chong Y, et al. Antibiotic rotation for febrile neutropenic patients with haematological malignancies: clinical significance of antibiotic heterogeneity. PLoS One 2013;8:e54190

Chung GW, et al. Antimicrobial stewardship: a review of prospective audit and feedback systems and an objective evaluation of outcomes. Virulence 2013;4:151-7

Davey P, et al. Interventions to improve antibiotic prescribing practices for hospital inpatients. Cochrane Database Syst 2013;4:CD003543

Delory T, et al. Impact of a program combining pre-authorization requirement and post-prescription review of carbapenems: an interrupted time-series analysis. Eur J Clin Microbiol Infect Dis 2013 Dec;32(12):1599-604

Embi PJ, et al. Computerized provider documentation: findings and implications of a multisite study of clinicians and administrators. J Am Med Inform Assoc 2013 Jul-Aug;20(4):718-26

Filice GA, et al. Use of a computer decision support system and antimicrobial therapy appropriateness. Infect Control Hosp Epidemiol 2013;34:558-65

Forrest CB, et al. Improving adherence to otitis media guidelines with clinical decision support and physician feedback. Pediatrics 2013;131:e1071-81

Gerber JS, et al. Effect of an outpatient antimicrobial stewardship intervention on broad-spectrum antibiotic prescribing by primary care pediatricians: a randomized trial. JAMA 2013 Jun 12;309(22):2345-52

Gonzales R, et al. A cluster randomized trial of decision support strategies for reducing antibiotic use in acute bronchitis. JAMA Intern Med 2013;173:267-73

Jardin CG, et al. Assessment of treatment patterns and patient outcomes before vs after implementation of a severity-based Clostridium difficile infection treatment policy. J Hosp Infect 2013 Sep;85(1):28-32

Jury LA, et al. A Clostridium difficile infection (CDI) stewardship initiative improves adherence to practice guidelines for management of CDI. Infect Control Hosp Epidemiol 2013 Nov;34(11):1222-4

Kim YC, et al. Trend of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in an institution with a high rate of MRSA after the reinforcement of antibiotic stewardship and hand hygiene. Am J Infect Control 2013 May;41(5):e39-43

Kullar R, et al. The EPIC challenge of optimizing antimicrobial stewardship: the role of electronic medical records and technology. Clin Infect Dis 2013 Oct;57(7):1005-13

Lin YS, et al. Impact of an antimicrobial stewardship program with multidisciplinary cooperation in a community public teaching hospital in Taiwan. Am J Infect Control 2013 Nov;41(11):1069-72

Mondain V, et al. A 6-year antifungal stewardship programme in a teaching hospital. Infection 2013 Jun;41(3):621-8

Mondain V, et al. An antibiotic stewardship program in a French teaching hospital. Med Mal Infect 2013;43:17-21.

Ostrowsky B, et al. Antimicrobial stewardship and automated pharmacy technology improve antibiotic appropriateness for community-acquired pneumonia. Infect Control Hosp Epidemiol 2013;34:566-72

Ramírez E, et al. Improving linezolid use decreases the incidence of resistance among Gram-positive microorganisms. Int J Antimicrob Agents 2013;41:174-8

Reed EE, et al. Impact of formulary restriction with prior authorization by an antimicrobial stewardship program. Virulence 2013;4:158-62

Rimawi RH, et al. Impact of regular collaboration between infectious diseases and critical care practitioners on antimicrobial utilization and patient outcome. Crit Care Med 2013 Sep;41(9):2099-107

Webber EC, et al. Conversion of a single-facility pediatric antimicrobial stewardship program to multi- facility application with computerized provider order entry and clinical decision support. Appl Clin Inform 2013 Nov 27;4(4):556-68

Weston A, et al. The impact of a Massachusetts state-sponsored educational program on antimicrobial stewardship in acute care hospitals. Infect Control Hosp Epidemiol 2013 Apr;34(4):437-9

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2012

Aldeyab MA, et al. An evaluation of the impact of antibiotic stewardship on reducing the use of high-risk antibiotics and its effect on the incidence of Clostridium difficile infection in hospital settings. J Antimicrob Chemother 2012;67:2988-96

Ash JS, et al. Standard practices for computerized clinical decision support in community hospitals: a national survey. J Am Med Inform Assoc 2012;19:980-7

Baker SN, et al. Pharmacist-managed antimicrobial stewardship program for patients discharged from the emergency department. J Pharm Pract 2012 Apr;25(2):190-4

Cooley TW, et al. Implementation of computerized prescriber order entry in four academic medical centers. Am J Health Syst Pharm 2012;69:2166-73

Cosgrove SE, et al. Evaluation of post-prescription review and feedback as a method of promoting rational antimicrobial use: a multicenter intervention. Infect Control Hosp Epidemiol 2012;33:374-80

Diaz Granados CA. Prospective audit for antimicrobial stewardship in intensive care: impact on resistance and clinical outcomes. Am J Infect Control 2012;40:526-9

Dryden M, et al. Antibiotic stewardship and early discharge from hospital: impact of a structured approach to antimicrobial management. J Antimicrob Chemother 2012;67:2289-96

Elligsen M, et al. Audit and feedback to reduce broad-spectrum antibiotic use among intensive care unit patients: a controlled interrupted time series analysis. Infect Control Hosp Epidemiol 2012 Apr;33(4):354-61

Elligsen M, et al. Prospective audit and feedback of antimicrobial stewardship in critical care: program implementation, experience, and challenges. Can J Hosp Pharm 2012;65:31-6

Evans RS,et al. Clinical use of an enterprise data warehouse. AMIA Annu Symp Proc 2012;2012:189-98

Goff DA. iPhones, iPads, and medical applications for antimicrobial stewardship. Pharmacotherapy 2012;32:657-61

Hashino S, et al. Clinical impact of cycling the administration of antibiotics for febrile neutropenia in Japanese patients with hematological malignancy. Eur J Clin Microbiol Infect Dis 2012;31:173-8

Heenen S, et al. Antibiotic strategies in severe nosocomial sepsis: why do we not de-escalate more often? Crit Care Med 2012;40:1404-9

Hermsen ED, et al. Implementation of a clinical decision support system for antimicrobial stewardship. Infect Control Hosp Epidemiol 2012 Apr;33(4):412-5

Johnston T, et al. Audit of Staphylococcus aureus bacteraemia management in NHS Tayside and comparison with European Antibiotic Strategies study group international quality standards. J Antimicrob Chemother 2012 Sep;67(9):2304-6

Katsios CM, et al. An antimicrobial stewardship program improves antimicrobial treatment by culture site and the quality of antimicrobial prescribing in critically ill patients. Crit Care 2012;16:R216

Kaye KS. Antimicrobial de-escalation strategies in hospitalized patients with pneumonia, intra- abdominal infections, and bacteremia. J Hosp Med 2012;7:S13-21

Kellie SM. Antimicrobial stewardship on the frontier: a pilot study of training using an electronic learning network. Infect Control Hosp Epidemiol 2012 Nov;33(11):1181-3

Lewis GJ, et al. Decreased resistance of Pseudomonas aeruginosa with restriction of ciprofloxacin in a large teaching hospital’s intensive care and intermediate care units. Infect Control Hosp Epidemiol 2012 Apr;33(4):368-73

Litvin CB, et al. Adoption of a clinical decision support system to promote judicious use of antibiotics for acute respiratory infections in primary care. Int J Med Inform 2012;81:521-6

Montravers P, et al. De-escalation: in drug we trust. Crit Care Med 2012;40:1645-6

Newman RE, et al. Impact of a guideline on management of children hospitalized with community- acquired pneumonia. Pediatrics 2012;129:e597-604

Pate PG, et al. Implementation of an antimicrobial stewardship program at a 60-bed long-term acute care hospital. Infect Control Hosp Epidemiol 2012 Apr;33(4):405-8

Patel SJ, et al. Development of an antimicrobial stewardship intervention using a model of actionable feedback. Interdiscip Perspect Infect Dis 2012;2012:150367

Patel J, et al. Effective use of a clinical decision-support system to advance antimicrobial stewardship. Am J Health Syst Pharm 2012;69:1543-4

Po JL, et al. The impact of an infectious diseases specialist-directed computerized physician order entry antimicrobial stewardship program targeting linezolid use. Infect Control Hosp Epidemiol 2012 Apr;33(4):434-5

Potasman I, et al. Impact of a computerized integrated antibiotic authorization system. Isr Med Assoc J 2012;14:415-9

Rauniar GP, et al. Effectiveness of an educational feedback intervention on drug prescribing in dental practice. Kathmandu Univ Med J (KUMJ) 2012;10:30-5

Rodrigues JF, et al. A computer-assisted prescription system to improve antibacterial surgical prophylaxis. Infect Control Hosp Epidemiol 2012;33:435-7

Rolston KV, et al. Antimicrobial de-escalation in cancer patients. Infection 2012;40:223-4

Sarraf-Yazdi S, et al. A 9-year retrospective review of antibiotic cycling in a surgical intensive care unit. J Surg Res 2012;176:e73-8

Shrestha NK, et al. Contribution of infectious disease consultation toward the care of inpatients being considered for community-based parenteral anti-infective therapy. J Hosp Med 2012;7:365-9

Smith MJ, et al. Effectiveness of antimicrobial guidelines for community-acquired pneumonia in children. Pediatrics 2012;129:e1326-33

Storey DF, et al. Implementation of an antimicrobial stewardship program on the medical surgical service of a 100-bed community hospital. Antimicrob Resist Infect Control 2012;1:32

Teo J, et al. The effect of a whole-system approach in an antimicrobial stewardship programme at the Singapore General Hospital. Eur J Clin Microbiol Infect Dis 2012;31:947-55

Vines C, Dean NC. Technology implementation impacting the outcomes of patients with CAP. Semin Respir Crit Care Med 2012;33:292-7

Wang HY, et al. Effectiveness of an integrated CPOE decision-supporting system with clinical pharmacist monitoring practice in preventing antibiotic dosing errors. Int J Clin Pharmacol Ther 2012;50:375-82

Wilde AM, et al. Inappropriate antibiotic use due to decreased compliance with a ventilator-associated pneumonia computerized clinical pathway: implications for continuing education and prospective feedback. Pharmacotherapy 2012 Aug;32(8):755-63

Yam P, et al. Implementation of an antimicrobial stewardship program in a rural hospital. Am J Health Syst Pharm 2012;69:1142-8

Yeo CL, et al. Prospective audit and feedback on antibiotic prescription in an adult hematology-oncology unit in Singapore. Eur J Clin Microbiol Infect Dis 2012 Apr;31(4):583-90

Zaidi ST, Marriott JL. Barriers and facilitators to adoption of a web-based antibiotic decision support system. South Med Rev 2012;5:42-50

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2011

Best JT, et al. Implementation of an evidence-based order set to impact initial antibiotic time intervals in adult febrile neutropenia. Oncol Nurs Forum 2011;38:661-8

Bjerrum L, et al. Health Alliance for prudent antibiotic prescribing in patients with respiratory tract infections (HAPPY AUDIT)‒impact of a non-randomised multifaceted intervention programme. BMC Fam Pract 2011;12:52

Chan YY, et al. Implementation and outcomes of a hospital-wide computerised antimicrobial stewardship programme in a large medical centre in Taiwan. Int J Antimicrob Agents 2011;38:486-92

Dunn K, et al. Implementing a pharmacist-led sequential antimicrobial therapy strategy: a controlled before-and-after study. Int J Clin Pharm 2011;33:208-14

Enoch DA, et al. Outcome for Gram-negative bacteraemia when following restrictive empirical antibiotic guidelines. QJM 2011;104:411-9

Ewig S. Nosocomial pneumonia: de-escalation is what matters. Lancet Infect Dis 2011;11:155-7

Haynes K, et al. Effectiveness of an information technology intervention to improve prophylactic antibacterial use in the postoperative period. J Am Med Inform Assoc 2011;18:164-8

Heintz BH, et al. Impact of a multidisciplinary team review of potential outpatient parenteral antimicrobial therapy prior to discharge from an academic medical center. Ann Pharmacother 2011 Nov;45(11):1329-37

Kazemi A, et al. The effect of computerized physician order entry and decision support system on medication errors in the neonatal ward: experiences from an Iranian teaching hospital. J Med Syst 2011;35:25-37

Kouyos RD, et al. Informed switching strongly decreases the prevalence of antibiotic resistance in hospital wards. PLoS Comput Biol 2011;7:e1001094

Landis Lewis Z, et al. The feasibility of automating audit and feedback for ART guideline adherence in Malawi. J Am Med Inform Assoc 2011;18:868-74

Lima AL, et al. Carbapenem stewardship: positive impact on hospital ecology. Braz J Infect Dis 2011;15:1-5

Mansouri MD, et al. Impact of an antibiotic restriction program on antibiotic utilization in the treatment of community-acquired pneumonia in a Veterans Affairs Medical Center. Infection 2011;39:53-8

Masterton RG. Antibiotic de-escalation. Crit Care Clin 2011;27:149-62

McKinley BA, et al. Computer protocol facilitates evidence-based care of sepsis in the surgical intensive care unit. J Trauma 2011;70:1153-66; discussion 1166-7

Medina Presentado JC, et al. Ceftriaxone and ciprofloxacin restriction in an intensive care unit: less incidence of Acinetobacter spp. and improved susceptibility of Pseudomonas aeruginosa. Rev Panam Salud Publica 2011;30:603-9

Niederman MS, Soulountsi V. De-escalation therapy: is it valuable for the management of ventilator- associated pneumonia? Clin Chest Med 2011;32:517-34

Oliveira PR, et al. Impact of restriction of cefepime use on the antimicrobial susceptibility of gram- negative bacilli related to healthcare-associated infections in an orthopedic hospital. Infect Drug Resist 2011;4:149-54

Ribner BS, et al. A web-based program to ensure compliance of medical staff providers with mandated health care facility requirements. Am J Infect Control 2011;39:511-4

Shime N, et al. De-escalation of antimicrobials in the treatment of bacteraemia due to antibiotic- sensitive pathogens in immunocompetent patients. Infection 2011;39:319-25

Skrlin J, et al. Impact of ceftriaxone de-restriction on the occurrence of ESBL-positive bacterial strains and antibiotic consumption. J Chemother 2011;23:341-4

Talpaert MJ, et al. Impact of guidelines and enhanced antibiotic stewardship on reducing broad- spectrum antibiotic usage and its effect on incidence of Clostridium difficile infection. J Antimicrob Chemother 2011;66:2168-74

Trautner BW, et al. A hospital-site controlled intervention using audit and feedback to implement guidelines concerning inappropriate treatment of catheter-associated asymptomatic bacteriuria. Implement Sci 2011;6:41

Wald HL, Kramer AM. Feasibility of audit and feedback to reduce postoperative urinary catheter duration. J Hosp Med 2011;6:183-9

Westphal JF, et al. Enhanced physician adherence to antibiotic use guidelines through increased availability of guidelines at the time of drug ordering in hospital setting. Pharmacoepidemiol Drug Saf 2011;20:162-8

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2010

Apisarnthanarak A,et al. Impact of education and an antifungal stewardship program for candidiasis at a Thai tertiary care center. Infect Control Hosp Epidemiol 2010;31:722-7

Beardmore RE, Pena-Miller R. Antibiotic cycling versus mixing: the difficulty of using mathematical models to definitively quantify their relative merits. Math Biosci Eng 2010;7:923-33

Beardmore RE, Pena-Miller R. Rotating antibiotics selects optimally against antibiotic resistance, in theory. Math Biosci Eng 2010;7:527-52

Braxton CC, et al. Improving antibiotic stewardship: order set implementation to improve prophylactic antimicrobial prescribing in the outpatient surgical setting. J Ambul Care Manage 2010;33:131-40

Cooke J, et al. Antimicrobial stewardship: an evidence-based, antimicrobial self-assessment toolkit (ASAT) for acute hospitals. J Antimicrob Chemother 2010;65:2669-73

Enne VI. Reducing antimicrobial resistance in the community by restricting prescribing: can it be done? J Antimicrob Chemother 2010;65:179-82

Fowkes CT, et al. Audit of physicians' adherence to a preprinted order set for community-acquired pneumonia. Can J Hosp Pharm 2010;63:289-94

Helmons PJ, et al. Using a clinical decision support system to determine the quality of antimicrobial dosing in intensive care patients with renal insufficiency. Qual Saf Health Care 2010;19:22-6

Hibbard ML, et al. Empiric, broad-spectrum antibiotic therapy with an aggressive de-escalation strategy does not induce gram-negative pathogen resistance in ventilator-associated pneumonia. Surg Infect (Larchmt) 2010;11:427-32

Laible BR, et al. Implementation of a pharmacist-led antimicrobial management team in a community teaching hospital: use of pharmacy residents and pharmacy students in a prospective audit and feedback approach. J Pharm Pract 2010;23:531-5

Morel J, et al. De-escalation as part of a global strategy of empiric antibiotherapy management. A retrospective study in a medico-surgical intensive care unit. Crit Care 2010;14:R225

Rattanaumpawan P, et al. Effectiveness of drug use evaluation and antibiotic authorization on patients' clinical outcomes, antibiotic consumption, and antibiotic expenditures. Am J Infect Control 2010;38:38-43

Schlueter M, et al. Practice patterns for antibiotic de-escalation in culture-negative healthcare-associated pneumonia. Infection 2010;38:357-62

Winters BD, et al. Impact of a restrictive antimicrobial policy on the process and timing of antimicrobial administration. J Hosp Med 2010;5:E41-5

Yong MK, et al. Improved susceptibility of Gram-negative bacteria in an intensive care unit following implementation of a computerized antibiotic decision support system. J Antimicrob Chemother 2010;65:1062-9

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Stewardship: Optimizing Drug Use

(Pharmacokinetic monitoring, dosing strategies for broad spectrum beta-lactam antibiotics, increasing use of oral antibiotics, allergy assessments, reducing antibiotic duration)

2016
2015
2014
2013
2012
2011
2010

2016

Ashfaq A, Zhu A, Iyengar A, et al. Impact of an institutional antimicrobial stewardship program on bacteriology of surgical site infections in cardiac surgery. J Card Surg 2016 Jun;31(6):367-72

Bairy LK, Nayak V, A A, et al. Advances in pharmacovigilance initiatives surrounding antimicrobial resistance — Indian perspective. Expert Opin Drug Saf 2016 May 13:1-8

Bassetti M, Welte T, Wunderink RG. Treatment of Gram-negative pneumonia in the critical care setting: is the beta-lactam antibiotic backbone broken beyond repair? Crit Care 2016 Jan 29;20:19

Davis LC, Covey RB, Weston JS, et al. Pharmacist-driven antimicrobial optimization in the emergency department. Am J Health Syst Pharm 2016 Mar 1;73(5 Suppl 1):S49-56

De Bus L, Denys W, Catteeuw J, et al. Impact of de-escalation of beta-lactam antibiotics on the emergence of antibiotic resistance in ICU patients: a retrospective observational study. Intensive Care Med 2016 Jun;42(6):1029-39

Estep PM, Ferreira JA, Dupree LH, et al. Impact of an antimicrobial stewardship initiative to evaluate beta-lactam allergy in patients ordered aztreonam. Am J Health Syst Pharm 2016 Mar 1;73(5 Suppl 1):S8-13

Monogue ML, Kuti JL, Nicolau DP. Optimizing antibiotic dosing strategies for the treatment of Gram-negative infections in the era of resistance. Expert Rev Clin Pharmacol 2016 Jan 16;9(3):459-76

Nguyen-Ha PT, Howrie D, Crowley K, et al. A quality assessment of a collaborative model of a pediatric antimicrobial stewardship program. Pediatrics 2016 Apr;137(4):e20150316

Niwa T, Watanabe T, Goto T, et al. Daily review of antimicrobial use facilitates the early optimization of antimicrobial therapy and improves clinical outcomes of patients with bloodstream infections. Biol Pharm Bull 2016 May 1;39(5):721-7

Niwa T, Watanabe T, Suzuki K, et al. Early optimization of antimicrobial therapy improves clinical outcomes of patients administered agents targeting methicillin-resistant Staphylococcus aureus. J Clin Pharm Ther 2016 Feb;41(1):19-25

Paul M, Dickstein Y, Raz-Pasteur A. Antibiotic de-escalation for bloodstream infections and pneumonia: systematic review and meta-analysis. Clin Microbiol Infect 2016 (published online Jun 6)

Swearingen SM, White C, Weidert S, et al. A multidimensional antimicrobial stewardship intervention targeting aztreonam use in patients with a reported penicillin allergy. Int J Clin Pharm 2016 Apr;38(2):213-7

Tabah A, Cotta MO, Garnacho-Montero J, et al.; Working Group for Antimicrobial Use in the ICU. A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the intensive care unit. Clin Infect Dis 2016 Apr 15;62(8):1009-17

Trubiano JA, Chen C, Cheng AC, et al.; National Antimicrobial Prescribing Survey (NAPS). Antimicrobial allergy 'labels' drive inappropriate antimicrobial prescribing: lessons for stewardship. J Antimicrob Chemother 2016 Jun;71(6):1715-22

Veve MP, Wagner JL, Kenney RM, et al. Comparison of fosfomycin to ertapenem for outpatient or step-down therapy of extended-spectrum beta-lactamase urinary tract infections. Int J Antimicrob Agents 2016 Jul;48(1):56-60

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2015

Abdul-Aziz MH, Lipman J, Mouton JW, et al. Applying pharmacokinetic/pharmacodynamic principles in critically ill patients: optimizing efficacy and reducing resistance development. Semin Respir Crit Care Med 2015 Feb;36(1):136-53

Aliberti S, Giuliani F, Ramirez J, et al. How to choose the duration of antibiotic therapy in patients with pneumonia. Curr Opin Infect Dis 2015 Apr;28(2):177-84

Arena F, Scolletta S, Marchetti L, et al. Impact of a clinical microbiology-intensive care consulting program in a cardiothoracic intensive care unit. Am J Infect Control 2015 (published online Jun 3)

Barber KE, Werth BJ, Rybak MJ. The combination of ceftaroline plus daptomycin allows for therapeutic de-escalation and daptomycin sparing against MRSA. J Antimicrob Chemother 2015 Feb;70(2):505-9

Barrett J, Edgeworth J, Wyncoll D. Shortening the course of antibiotic treatment in the intensive care unit. Expert Rev Anti Infect Ther 2015 Apr;13(4):463-71

Bassetti M, De Waele JJ, Eggimann P, et al. Preventive and therapeutic strategies in critically ill patients with highly resistant bacteria. Intensive Care Med 2015 May;41(5):776-95

Beique L, Zvonar R. Addressing concerns about changing the route of antimicrobial administration from intravenous to oral in adult inpatients. Can J Hosp Pharm 2015 Jul-Aug;68(4):318-26

del Arco A, Tortajada B, de la Torre J, et al. The impact of an antimicrobial stewardship programme on the use of antimicrobials and the evolution of drug resistance. Eur J Clin Microbiol Infect Dis 2015 Feb;34(2):247-51

Fantoni M, Murri R, Scoppettuolo G, et al. Resource-saving advice from an infectious diseases specialist team in a large university hospital: an exportable model? Future Microbiol 2015;10(1):15-20

Furtado GH, Cardinal L, Macedo RS, et al. Pharmacokinetic/pharmacodynamic target attainment of intravenous beta-lactam regimens against gram-negative bacteria isolated in a Brazilian teaching hospital. Rev Soc Bras Med Trop 2015 Sep-Oct;48(5):539-45

Gilchrist M, Seaton RA. Outpatient parenteral antimicrobial therapy and antimicrobial stewardship: challenges and checklists. J Antimicrob Chemother 2015 Apr;70(4):965-70

Goldman JL, Lee BR, Hersh AL, et al. Clinical diagnoses and antimicrobials predictive of pediatric antimicrobial stewardship recommendations: a program evaluation. Infect Control Hosp Epidemiol 2015 Jun;36(6):673-80

Knackstedt ED, Stockmann C, Davis CR, et al. Outpatient parenteral antimicrobial therapy in pediatrics: an opportunity to expand antimicrobial stewardship. Infect Control Hosp Epidemiol 2015 Feb;36(2):222-4

Lawson W, Nathwani D, Eckmann C, et al. Weight-based antibiotic dosing in a real-world European study of complicated skin and soft-tissue infections due to methicillin-resistance Staphylococcus aureus. Clin Microbiol Infect 2015 Sep;21(Suppl 2):S40-6

Lesprit P, de Pontfarcy A, Esposito-Farese M, et al. Postprescription review improves in-hospital antibiotic use: a multicenter randomized controlled trial. Clin Microbiol Infect 2015 Feb;21(2):180.e1-7

Lew KY, Ng TM, Tan M, et al. Safety and clinical outcomes of carbapenem de-escalation as part of an antimicrobial stewardship programme in an ESBL-endemic setting. J Antimicrob Chemother 2015 Apr;70(4):1219-25

Loo LW, Liew YX, Lee W, et al. Impact of antimicrobial stewardship program (ASP) on outcomes in patients with acute bacterial skin and skin structure infections (ABSSSIs) in an acute-tertiary care hospital. Infect Dis Ther 2015 Sep;4(Suppl 1):15-25

Nathwani D, Lawson W, Dryden M, et al. Implementing criteria-based early switch/early discharge programmes: a European perspective. Clin Microbiol Infect 2015 Sep;21(Suppl 2):S47-55

Nguyen CT, Gandhi T, Chenoweth C, et al. Impact of an antimicrobial stewardship-led intervention for Staphylococcus aureus bacteraemia: a quasi-experimental study. J Antimicrob Chemother 2015 Dec;70(12):3390-6

Niwa T, Watanabe T, Suzuki K, et al. Early optimization of antimicrobial therapy improves clinical outcomes of patients administered agents targeting methicillin-resistant Staphylococcus aureus. J Clin Pharm Ther 2015 (published online Dec 18)

Singh S, Zhang YZ, Chalkley S, et al. A three-point time series study of antibiotic usage on an intensive care unit, following an antibiotic stewardship programme, after an outbreak of multi-resistant Acinetobacter baumannii. Eur J Clin Microbiol Infect Dis 2015 Sep;34(9):1893-900

Spivak ES, Kendall B, Orlando P, et al. Evaluation of outpatient parenteral antimicrobial therapy at a Veterans Affairs hospital. Infect Control Hosp Epidemiol 2015 Sep;36(9):1103-5

Tabah A, Cotta MO, Garnacho-Montero J, et al. A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the intensive care unit. Clin Infect Dis 2015 (published online Dec 23)

Thompson C, Zahradnik M, Brown A, et al. The use of an IV to PO clinical intervention form to improve antibiotic administration in a community based hospital. BMJ Qual Improv Rep 2015 Jan 29;4(1):u200786.w2247

Weiss E, Zahar JR, Lesprit P, et al. Elaboration of a consensual definition of de-escalation allowing a ranking of beta-lactams. Clin Microbiol Infect 2015 Jul;21(7):649.e1-10

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2014

Ahmad F, Pogue JM, Marchaim D, et al. Evaluation of the potential impact of a carbapenem de-escalation program in an academic healthcare system. J Infect Public Health 2014 Feb;7(1):50-3

Bartlett JM, Siola PL. Implementation and first-year results of an antimicrobial stewardship program at a community hospital. Am J Health Syst Pharm 2014 Jun 1;71(11):943-9

Blanchette LM, Kuti JL, Nicolau DP, et al. Clinical comparison of ertapenem and cefepime for treatment of infections caused by AmpC beta-lactamase-producing Enterobacteriaceae. Scand J Infect Dis 2014 Nov;46(11):803

Braykov NP, Morgon DJ, Schweizer ML, et al. Assessment of empirical antibiotic therapy optimisation in six hospitals: an observational cohort study. Lancet Infect Dis 2014 Dec;14(12):1220-7

Buyle RM, Wallaert M, Beck N, et al. Implementation of a multidisciplinary infectious diseases team in a tertiary hospital within an antimicrobial stewardship program. Acta Clin Belg 2014 Oct;69(5):320-6

Cotta MO, Roberts JA, Tabah A, et al. Antimicrobial stewardship of beta-lactams in intensive care units. Expert Rev Anti Infect Ther 2014 May;12(5):581-95

Eckmann C, Lawson W, Nathwani D, et al. Antibiotic treatment patterns across Europe in patients with complicated skin and soft-tissue infections due to meticillin-resistant Staphylococcus aureus: a plea for implementation of early switch and early discharge criteria. Int J Antimicrob Agents 2014 Jul;44(1):56-64

El Houfi A, Javed N, Nathwani D, et al. Early switch/early discharge opportunities for hospitalized patients with methicillin-resistant Staphylococcus aureus complicated skin and soft tissue infections: proof of concept in the United Arab Emirates. Value Health 2014 Nov;17(7):A683

Fagan M, Lindbaek M, Reiso H, et al. A simple intervention to reduce inappropriate ciprofloxacin prescribing in the emergency department. Scand J Infect Dis 2014 Jul;46(7):481-5

Guillard P, de La Blanchardiere A, Cattoir V, et al. Antimicrobial stewardship and linezolid. Int J Clin Pharm 2014 Oct;36(5):1059-68

Landry E, Sulz L, Bell A, et al. Urinary tract infections: leading initiatives in selecting empiric outpatient treatment (UTILISE). Can J Hosp Pharm 2014 Mar;67(2):116-25

MacVane SH, Kuti JL, Nicolau DP. Clinical pharmacodynamics of antipseudomonal cephalosporins in patients with ventilator-associated pneumonia. Antimicrob Agents Chemother 2014 Mar;58(3):1359-64

MacVane SH, Kuti JL, Nicolau DP. Prolonging beta-lactam infusion: a review of the rationale and evidence, and guidance for implementation. Int J Antimicrob Agents 2014 Feb;43(2):105-13

Maddox ML, DeBoer EC, Hammerquist RJ. Administration of extended infusion piperacillin-tazobactam with the use of smart pump technology. Hosp Pharm 2014 May;49(5):444-8

Nathwani D, Eckmann C, Lawson W, et al. Pan-European early switch/early discharge opportunities exist for hospitalized patients with methicillin-resistant Staphylococcus aureus complicated skin and soft tissue infections. Clin Microbiol Infect 2014 Oct;20(10):993-1000.

Pinzone MR, Cacopardo B, Abbo, L, et al. Duration of antimicrobial therapy in community acquired pneumonia: less is more. Sci World J 2014 Jan 21;2014:759138

Sakoulas G, Moise PA, Casapao AM, et al. Antimicrobial salvage therapy for persistent staphylococcal bacteremia using daptomycin plus ceftaroline. Clin Ther 2014 Oct 1;36(10):1317-33

Shrayteh ZM, Rahal MK, Malaeb DN. Practice of switch from intravenous to oral antibiotics. Springerplus 2014 Dec 9;3:717

So W, Kuti JL, Nicolau DP. Population pharmacokinetics of cefazolin in serum and tissue for patients with complicated skin and soft tissue infections (cSSTI). Infect Dis Ther 2014 Dec;3(2):269-79

Vitrat V, Hautefeuille S, Janssen C, et al. Optimizing antimicrobial therapy in critically ill patients. Infect Drug Resist 2014 Oct 20;7:261-71

Wang HY, Chiu CH, Huang CT, et al. Blood culture-guided de-escalation of empirical antimicrobial regimen for critical patients in an online antimicrobial stewardship programme. Int J Antimicrob Agents 2014 Dec;44(6):520-7

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2013

Ampe E, et al. Implementation of a protocol for administration of vancomycin by continuous infusion: pharmacokinetic, pharmacodynamic and toxicological aspects. Int J Antimicrob Agents 2013;41:439- 46

Arnold HM, et al. Prolonged infusion antibiotics for suspected Gram-negative infections in the ICU: a before-after study. Ann Pharmacother 2013; 47:170-80

Bauer KA, et al. Extended-infusion cefepime reduces mortality in patients with Pseudomonas aeruginosa infections. Antimicrob Agents Chemother 2013 Jul;57(7):2907-12

Bhalodi AA, et al. Pharmacokinetics of doripenem in infected patients treated within and outside the intensive care unit. Ann Pharmacother. 2013 May;47(5):617-27

Bhalodi AA, et al. Pharmacokinetics of intravenous linezolid in moderately to morbidly obese adults. Antimicrob Agents Chemother 2013 Mar;57(3):1144-9

Bhalodi AA, et al. Tissue pharmacokinetics of cefazolin in patients with lower limb infections. Antimicrob Agents Chemother 2013 Nov;57(11):5679-83

Boyce JM, et al. A trial of discontinuation of empiric vancomycin therapy in patients with suspected methicillin-resistant Staphylococcus aureus health care-associated pneumonia. Antimicrob Agents Chemother 2013;57:1163-8

Butterfield JM, et al. Daptomycin pharmacokinetics and pharmacodynamics in a pooled sample of patients receiving thrice-weekly hemodialysis. Antimicrob Agents Chemother 2013;57:864-72

Carlier M, et al. Meropenem and piperacillin/tazobactam prescribing in critically ill patients: does augmented renal clearance affect pharmacokinetic/pharmacodynamic target attainment when extended infusions are used? Crit Care 2013;17:R84

Covajes C, et al. Continuous infusion of vancomycin in septic patients receiving continuous renal replacement therapy. Int J Antimicrob Agents 2013;41:261-6

Davis SL, et al. Adherence to the 2009 consensus guidelines for vancomycin dosing and monitoring practices: a cross-sectional survey of U.S. hospitals. Pharmacotherapy 2013 Dec;33(12):1256-63

De Waele JJ, et al. Factors associated with inadequate early vancomycin levels in critically ill patients treated with continuous infusion. Int J Antimicrob Agents 2013;41:434-8

Durante-Mangoni E, et al. Colistin and rifampicin compared with colistin alone for the treatment of serious infections due to extensively drug-resistant Acinetobacter baumannii: a multicenter, randomized clinical trial. Clin Infect Dis 2013 Aug;57(3):349-58

Falagas ME, et al. Clinical outcomes with extended or continuous versus short-term intravenous infusion of carbapenems and piperacillin/tazobactam: a systematic review and meta-analysis. Clin Infect Dis 2013;56:272-82

Falcone M, et al. Variability of pharmacokinetic parameters in patients receiving different dosages of daptomycin: is therapeutic drug monitoring necessary? J Infect Chemother 2013 Aug;19(4):732-9

Fernandez-Hidalgo N, et al. Ampicillin plus ceftriaxone is as effective as ampicillin plus gentamicin for treating Enterococcus faecalis infective endocarditis. Clin Infect Dis 2013;56:1261-8

Fissell WH. Antimicrobial dosing in acute renal replacement. Adv Chronic Kidney Dis 2013;20:85-93

Goff DA, et al. When pharmacodynamics trump costs: an antimicrobial stewardship program's approach to selecting optimal antimicrobial agents. Clin Ther 2013 Jun;35(6):766-71

Golenia BS, et al. Evaluation of a vancomycin dosing nomogram based on the Modification of Diet in Renal Disease equation in intensive care unit patients. J Crit Care 2013 Oct;28(5):710-6

Haeseker M, et al. The ciprofloxacin target AUC: MIC ratio is not reached in hospitalized patients with the recommended dosing regimens. Br J Clin Pharmacol 2013;75:180-5

Hermsen ED, et al. Failure of a pharmacist-initiated antimicrobial step-down protocol to impact physician prescribing behaviour or patient outcomes: a quasi-experimental, cross-over study. J Hosp Admin 2013;2:62-70

Kiratisin P, et al. Pharmacodynamic profiling of doripenem, imipenem and meropenem against prevalent Gram-negative organisms in the Asia-Pacific region. Int J Antimicrob Agents 2013 Jan;41(1):47-51

Kullar R, et al. Implementation of an antimicrobial stewardship pathway with daptomycin for optimal treatment of methicillin-resistant Staphylococcus aureus bacteremia. Pharmacotherapy 2013;33:3-10

Montoya M, et al. Antimicrobial selection and its impact on the incidence of clostridium difficile- associated diarrhea. J Pharm Pract 2013 Oct;26(5):483-7

Murray KP, et al. Early use of daptomycin versus vancomycin for methicillin-resistant Staphylococcus aureus bacteremia with vancomycin minimum inhibitory concentration ≥ 1 mg/L: a matched cohort study. Clin Infect Dis 2013;56:1562-9

Paciullo CA, et al. Vancomycin clearance in high-volume venovenous hemofiltration. Ann Pharmacother 2013;47:e14

Preiswerk B, et al. Experience with daptomycin daily dosing in ICU patients undergoing continuous renal replacement therapy. Infection 2013;41:553-7

Raman K, et al. Early antibiotic discontinuation in patients with clinically suspected ventilator-associated pneumonia and negative quantitative bronchoscopy cultures. Crit Care Med 2013 Jul;41(7):1656-63

Sallach-Ruma R, et al. Evaluation of outcomes of intravenous to oral antimicrobial conversion initiatives: a literature review. Expert Rev Clin Pharmacol 2013 Nov;6(6):703-29

Saugel B, et al. Continuous intravenous administration of vancomycin in medical intensive care unit patients. J Crit Care 2013;28:9-13

Schulz L, et al. The use of best practice alerts with the development of an antimicrobial stewardship navigator to promote antibiotic de-escalation in the electronic medical record. Infect Control Hosp Epidemiol 2013 Dec;34(12):1259-65

Silva BN, et al. De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock. Cochrane Database Syst Rev 2013;3:CD007934

Takahashi Y, et al. Preferable timing of therapeutic drug monitoring in patients with impaired renal function treated with once-daily administration of vancomycin. J Infect Chemother 2013 Aug;19(4):709-16

Udy AA, et al. Can population pharmacokinetic modelling guide vancomycin dosing during continuous renal replacement therapy in critically ill patients? Int J Antimicrob Agents 2013;41:564-8

Vandecasteele SJ, et al. The pharmacokinetics and pharmacodynamics of vancomycin in clinical practice: evidence and uncertainties. J Antimicrob Chemother 2013;68:743-8

Zelenitsky S, et al. Vancomycin pharmacodynamics and survival in patients with methicillin-resistant Staphylococcus aureus-associated septic shock. Int J Antimicrob Agents 2013;41:255-60

Zhao W, et al. Vancomycin continuous infusion in neonates: dosing optimisation and therapeutic drug monitoring. Arch Dis Child 2013;98:449-53

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2012

Avdic E, et al. Impact of an antimicrobial stewardship intervention on shortening the duration of therapy for community-acquired pneumonia. Clin Infect Dis 2012;54:1581-7

Bhalodi AA, et al. Pharmacokinetics of intravenous linezolid in moderately to morbidly obese adults. Antimicrob Agents Chemother 2013 Mar;57(3):1144-9

Buyle FM, et al. Prospective multicentre feasibility study of a quality of care indicator for intravenous to oral switch therapy with highly bioavailable antibiotics. J Antimicrob Chemother 2012;67:2043-6

Deresinski S. Methicillin-resistant Staphylococcus aureus and vancomycin: minimum inhibitory concentration matters. Clin Infect Dis 2012 Mar;54(6):772-4

Duszynska W, et al. Continuous infusion of piperacillin/tazobactam in ventilator-associated pneumonia: a pilot study on efficacy and costs. Int J Antimicrob Agents 2012;39:153-8

El Nekidy WS, et al. Factors influencing vancomycin loading dose for hospitalized hemodialysis patients: prospective observational cohort study. Can J Hosp Pharm 2012;65:436-42

Frazee EN, et al. Effect of continuous venovenous hemofiltration dose on achievement of adequate vancomycin trough concentrations. Antimicrob Agents Chemother 2012;56:6181-5

Geli P, et al. “One-size-fits-all”? Optimizing treatment duration for bacterial infections. PLoS One 2012;7(1):e29838

Georges B, et al. Ceftazidime dosage regimen in intensive care unit patients: from a population pharmacokinetic approach to clinical practice via Monte Carlo simulations. Br J Clin Pharmacol 2012;73:588-96

George JM, et al. Prolonged infusions of beta-lactam antibiotics: implication for antimicrobial stewardship. Pharmacotherapy 2012;32:707-21

Jamal JA, et al. Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy, and extracorporeal membrane oxygenation. Curr Opin Crit Care 2012;18:460-71

Jones M, et al. Parenteral to oral conversion of fluoroquinolones: low-hanging fruit for antimicrobial stewardship programs? Infect Control Hosp Epidemiol 2012 Apr;33(4):362-7

Lee GC, et al. Outcomes of extended-infusion piperacillin-tazobactam: a retrospective analysis of critically ill patients. Clin Ther 2012;34:2297-300

Lee SL, et al. Clinicians' knowledge, beliefs and acceptance of intravenous-to-oral antibiotic switching, Hospital Pulau Pinang. Med J Malaysia 2012;67:190-8

Lodise TP, et al. Telavancin pharmacokinetics and pharmacodynamics in patients with complicated skin and skin structure infections and various degrees of renal function. Antimicrob Agents Chemother 2012;56:2062-6

McKamy S, et al. Evaluation of a pediatric continuous-infusion vancomycin therapy guideline. Am J Health Syst Pharm 2012;69:2066-71

Minne L, et al. Five years of therapeutic drug monitoring in the intensive care did not change vancomycin prescription behaviour: perceived needs for decision support. Minerva Anestesiol 2012;78:684-92

Nicolau DP, et al. Carbapenem stewardship: does ertapenem affect Pseudomonas susceptibility to other carbapenems? A review of the evidence. Int J Antimicrob Agents 2012 Jan;39(1):11-5

Nichols KR, et al. System-wide implementation of the use of an extended-infusion piperacillin/tazobactam dosing strategy: feasibility of utilization from a children's hospital perspective. Clin Ther 2012;34:1459-65

Pea F, et al. Dosing nomograms for attaining optimum concentrations of meropenem by continuous infusion in critically ill patients with severe Gram-negative infections: a pharmacokinetics/pharmacodynamics-based approach. Antimicrob Agents Chemother 2012;56:6343- 8

Piper GL, Kaplan LJ. Antibiotic heterogeneity optimizes antimicrobial prescription and enables resistant pathogen control in the intensive care unit. Surg Infect (Larchmt) 2012;13:194-202

Reynolds DC, et al. Performance of a vancomycin dosage regimen developed for obese patients. Am J Health Syst Pharm 2012;69:944-50

Roberts JA, et al. How to optimise antimicrobial prescriptions in the intensive care unit: principles of individualised dosing using pharmacokinetics and pharmacodynamics. Int J Antimicrob Agents 2012;39:187-92

Silva DC, et al. Vancomycin serum concentrations in pediatric oncologic/hematologic intensive care patients. Braz J Infect Dis 2012;16:361-5

Sinnollareddy MG, et al. Beta-lactam pharmacokinetics and pharmacodynamics in critically ill patients and strategies for dose optimization: a structured review. Clin Exp Pharmacol Physiol 2012;39:489- 96

Soto Guerrero Y, et al. Evaluation of a vancomycin dosing regimen for patients on high flux hemodialysis: an observational study. Bol Asoc Med P R 2012;104:10-4

Tamma PD, et al. Combination therapy for treatment of infections with gram-negative bacteria. Clin Microbiol Rev 2012;25:450-70

Teo J, et al. The effect of a whole-system approach in an antimicrobial stewardship programme at the Singapore General Hospital. Eur J Clin Microbiol Infect Dis 2012;31:947-55

Tran TT, et al. Evaluation of a daptomycin dose-optimization protocol. Am J Health Syst Pharm 2012;69:979-84

Troger U, et al. Decreased meropenem levels in intensive care unit patients with augmented renal clearance: benefit of therapeutic drug monitoring. Int J Antimicrob Agents 2012;40:370-2

Walker MC, et al. Continuous and extended infusions of beta-lactam antibiotics in the pediatric population. Ann Pharmacother 2012;46:1537-46

Wilson FP, Berns JS. Vancomycin levels are frequently subtherapeutic during continuous venovenous hemodialysis (CVVHD). Clin Nephrol 2012;77:329-31

Wilson FP, et al. Low cefepime concentrations during high blood and dialysate flow continuous venovenous hemodialysis. Antimicrob Agents Chemother 2012;56:2178-80

Yen YH, et al. Clinical and economic impact of a pharmacist-managed I.V.-to-P.O. conversion service for levofloxacin in Taiwan. Int J Clin Pharmacol Ther 2012;50:136-41

Yoshizawa K, et al. Optimisation of imipenem regimens in patients with impaired renal function by pharmacokinetic-pharmacodynamic target attainment analysis of plasma and urinary concentration data. Int J Antimicrob Agents 2012;40:427-33

Zelenitsky SA, et al. Initial vancomycin dosing protocol to achieve therapeutic serum concentrations in patients undergoing hemodialysis. Clin Infect Dis 2012;55:527-33

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2011

Abuhasna S, Al Jundi AH. Therapeutic drug monitoring of vancomycin in an obese patient with renal insufficiency. J Anaesthesiol Clin Pharmacol 2011;27:531-3

Aubron C, et al. Evaluation of the accuracy of a pharmacokinetic dosing program in predicting serum vancomycin concentrations in critically ill patients. Ann Pharmacother 2011;45:1193-8

Bosso JA, et al. Relationship between vancomycin trough concentrations and nephrotoxicity: a prospective multicenter trial. Antimicrob Agents Chemother 2011;55:5475-9

Cardone KE, et al. Pharmacokinetics and pharmacodynamics of intravenous daptomycin during continuous ambulatory peritoneal dialysis. Clin J Am Soc Nephrol 2011;6:1081-8

Cheatham SC, et al. Steady-state pharmacokinetics and pharmacodynamics of cefepime administered by prolonged infusion in hospitalised patients. Int J Antimicrob Agents 2011;37:46-50

Cook AM, et al. Pharmacokinetics of intravenous levofloxacin administered at 750 milligrams in obese adults. Antimicrob Agents Chemother 2011;55:3240-3

Chung J, et al. Optimal dose of vancomycin for treating methicillin-resistant Staphylococcus aureus pneumonia in critically ill patients. Anaesth Intensive Care 2011;39:1030-7

Cirillo I, et al. Influence of continuous venovenous hemofiltration and continuous venovenous hemodiafiltration on the disposition of doripenem. Antimicrob Agents Chemother 2011;55:1187-93

Conil JM, et al. Tobramycin disposition in ICU patients receiving a once daily regimen: population approach and dosage simulations. Br J Clin Pharmacol 2011;71:61-71

Connor MJ Jr, et al. Therapeutic drug monitoring of piperacillin-tazobactam using spent dialysate effluent in patients receiving continuous venovenous hemodialysis. Antimicrob Agents Chemother 2011;55:557-60

Crandon JL, et al. Optimization of meropenem dosage in the critically ill population based on renal function. Intensive Care Med 2011 Apr;37(4):632-8

Crandon, JL, et al. Pharmacodynamic approaches to optimizing beta-lactam therapy. Crit Care Clin 2011 Jan;27(1):77-93

Drusano GL, Louie A. Optimization of aminoglycoside therapy. Antimicrob Agents Chemother 2011;55:2528-31

Dunn K, et al. Implementing a pharmacist-led sequential antimicrobial therapy strategy: a controlled before-and-after study. Int J Clin Pharm 2011;33:208-14

Frymoyer A, et al. Impact of a hospitalwide increase in empiric pediatric vancomycin dosing on initial trough concentrations. Pharmacotherapy 2011;31:871-6

Giachetto GA, et al. Vancomycin pharmacokinetic-pharmacodynamic parameters to optimize dosage administration in critically ill children. Pediatr Crit Care Med 2011;12:e250-4

Garonzik SM et al. Population pharmacokinetics of colistin methanesulfonate and formed colistin in critically ill patients from a multicenter study provide dosing suggestions for various categories of patients. Antimicrob Agents Chemother 2011;55:3284-94

Heil EL, et al. Validation of doripenem dosing in patients with end-stage renal disease receiving hemodialysis. Ann Pharmacother 2011 Nov; 45(11):1455-6

Housman ST, et al. Optimizing antibiotic pharmacodynamics in hospital-acquired and ventilator-acquired bacterial pneumonia. Clin Chest Med 2011 Sep;32(3):439-50

Jain R, et al. Implications of obesity for drug therapy: limitations and challenges. Clin Pharmacol Ther 2011;90:77-89

Kaufman SE, et al. Rationale and evidence for extended infusion of piperacillin-tazobactam. Am J Health Syst Pharm 2011;68:1521-6

Keel RA, et al. Pharmacodynamic evaluation of i.v. antimicrobials against Psedomonas aeruginosa samples collected from U.S. hospitals. Am J Health Syst Pharm 2011 Sep 1;68(17):1619-25

Keel, RA. Pharmacodynamic profiling of antimicrobials against gram-negative respiratory isolates from Canadian hospitals. Can J Infect Dis Med Microbiol 2011 Winter;22(4):132-6

Keel RA, et al. Pharmacokinetics of intravenous and oral linezolid in adults with cystic fibrosis. Antimicrob Agents Chemother 2011 Jul;55(7):3393-8

Khachman D, et al. Optimizing ciprofloxacin dosing in intensive care unit patients through the use of population pharmacokinetic-pharmacodynamic analysis and Monte Carlo simulations. J Antimicrob Chemother 2011;66:1798-809

Kullar R, et al. Validation of the effectiveness of a vancomycin nomogram in achieving target trough concentrations of 15-20 mg/L suggested by the vancomycin consensus guidelines. Pharmacotherapy 2011;31:441-8

Kumar A. Optimizing antimicrobial therapy in sepsis and septic shock. Crit Care Nurs Clin North Am 2011;23:79-97

Lodise TP, Butterfield J. Use of pharmacodynamic principles to inform beta-lactam dosing: "S" does not always mean success. J Hosp Med 2011;6:S16-23

Lodise TP, Drusano GL. Pharmacokinetics and pharmacodynamics: optimal antimicrobial therapy in the intensive care unit. Crit Care Clin 2011;27:1-18

Lomaestro BM. Vancomycin dosing and monitoring 2 years after the guidelines. Expert Rev Anti Infect Ther 2011;9:657-67

Mehta SA, Phillips MS. Combination therapy for septic shock: considerations for antibiotic stewardship. Crit Care Med 2011;39:608-9

McKenzie C. Antibiotic dosing in critical illness. J Antimicrob Chemother 2011;66(Suppl 2):ii25-ii32

Nadeau MC, Kuti EL. Clinical and economic impact of intravenous to oral conversion therapy programs. Conn Med 2011;75:25-9

Nicolau DP, et al. Bronchopulmonary pharmacokinetic and pharmacodynamics profiles of levofloxacin 750 mg once daily in adults undergoing treatment for actue exacerbation of chronic bronchitis. Pulm Pharmacol Ther 2012 Feb;25(1):94-8

Nielsen EI, et al. Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization. Antimicrob Agents Chemother 2011;55:4619-30

Nyman HA, et al. Comparative evaluation of the Cockcroft-Gault equation and the modification of diet in renal disease (MDRD) study equation for drug dosing: an opinion of the Nephrology Practice and Research Network of the American College of Clinical Pharmacy. Pharmacotherapy 2011;31:1130- 44

Ohata Y, et al. Optimal dosage regimen of meropenem for pediatric patients based on pharmacokinetic/pharmacodynamic considerations. Drug Metab Pharmacokinet 2011;26:523-31

Patel N, et al. Use of pharmacokinetic and pharmacodynamic principles to determine optimal administration of daptomycin in patients receiving standardized thrice-weekly hemodialysis. Antimicrob Agents Chemother 2011;55:1677-83

Rattanaumpawan P, et al. Impact of antimicrobial stewardship programme changes on unnecessary double anaerobic coverage therapy. J Antimicrob Chemother 2011;66:2655-8

Roberts JA, et al. Vancomycin dosing in critically ill patients: robust methods for improved continuous- infusion regimens. Antimicrob Agents Chemother 2011;55:2704-9

Roberts JA. Using PK/PD to optimize antibiotic dosing for critically ill patients. Curr Pharm Biotechnol 2011;12:2070-9

Rotschafer J, et al. Optimal use of fluoroquinolones in the intensive care setting. Crit Care Clin 2011 Jan;27(1):95-106

Ulldemolins M, et al. The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients. Clin Pharmacokinet 2011;50:99-110

Varghese JM, et al. Antimicrobial pharmacokinetic and pharmacodynamic issues in the critically ill with severe sepsis and septic shock. Crit Care Clin 2011;27:19-34

Vilay AM, et al. Daptomycin pharmacokinetics in critically ill patients receiving continuous venovenous hemodialysis. Crit Care Med 2011;39:19-25

Yamamoto T, et al. Proposal of a pharmacokinetically optimized dosage regimen of antibiotics in patients receiving continuous hemodiafiltration. Antimicrob Agents Chemother 2011;55:5804-12

Yost RJ, et al. The retrospective cohort of extended-infusion piperacillin-tazobactam (RECEIPT) study: a multicenter study. Pharmacotherapy 2011;31:767-75

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2010

Bal AM, et al. Antibiotic heterogeneity: from concept to practice. Ann N Y Acad Sci 2010;1213:81-91

Bazan JA, et al. Peramivir pharmacokinetics in two critically ill adults with 2009 H1N1 influenza A concurrently receiving continuous renal replacement therapy. Pharmacotherapy 2010 Oct;30(10):1016-20

Bulitta JB, et al. Population pharmacokinetic comparison and pharmacodynamics breakpoints of ceftazidime in cystic fibrosis patients and healthy volunteers. Antimicrob Agents Chemother 2010;54:1275-82

Burkhardt O, et al. Underdosing of ertapenem in critically ill patients with pneumonia confirmed by Monte Carlo simulations. Int J Antimicrob Agents 2010;35:96-7

Chapuis TM, et al. Prospective monitoring of cefepime in intensive care unit adult patients. Crit Care 2010;14:R51

Decker BS, et al. Vancomycin pharmacokinetics and pharmacodynamics during short daily hemodialysis. Clin J Am Soc Nephrol 2010;5:1981-7

Delattre IK, et al. Empirical models for dosage optimization of four beta-lactams in critically ill septic patients based on therapeutic drug monitoring of amikacin. Clin Biochem 2010;43:589-98

Giuliano C, et al. Use of vancomycin pharmacokinetic-pharmacodynamic properties in the treatment of MRSA infections. Expert Rev Anti Infect Ther 2010;8:95-106

Gomes Silva BN, et al. De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shock. Cochrane Database Syst Rev 2010;(12):CD007934

Helmons PJ,et al. Using a clinical decision support system to determine the quality of antimicrobial dosing in intensive care patients with renal insufficiency. Qual Saf Health Care 2010;19:22-6

Hermsen ED, et al. Clinical outcomes and nephrotoxicity associated with vancomycin trough concentrations during treatment of deep-seated infections. Expert Opin Drug Saf 2010;9:9-14

Imberti C, et al. Steady-state pharmacokinetics and BAL concentration of colistin in critically ill patients after IV colistin methanesulfonate administration. Chest 2010;138:1333-9

Kielstein JT, et al. Dosing of daptomycin in intensive care unit patients with acute kidney injury undergoing extended dialysis--a pharmacokinetic study. Nephrol Dial Transplant 2010;25:1537-41

Koomanachai P, et al. Pharmacodynamic modeling of intravenous antibiotics against gram-negative bacteria collected in the United States. Clin Ther 2010 Apr;32(4):766-79

Kumar A, et al. Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: a propensity-matched analysis. Crit Care Med 2010;38:1773-85

Legal M, Wan M. Influence of age on frequency of vancomycin dosing. Can J Hosp Pharm 2010;63:13-9

Logman JF, et al. Comparative effectiveness of antibiotics for the treatment of MRSA complicated skin and soft tissue infections. Curr Med Res Opin 2010 Jul;26(7):1565-78

Marques-Minana MR, et al. Population pharmacokinetic analysis of vancomycin in neonates. A new proposal of initial dosage guideline. Br J Clin Pharmacol 2010;70:713-20

Nicasio AM, et al. Length of stay and hospital costs associated with a pharmacodynamics-based clinical pathway for empiric antibiotic choice for ventilator-associated pneumonia. Pharmacotherapy 2010 May;30(5):453-62

Panais R, et al. A protocolized approach to vancomycin dosing in conventional hemodialysis. J Nephrol 2010;23:569-74

Patel N, et al. Determination of antibiotic dosage adjustments in patients with renal impairment: elements for success. J Antimicrob Chemother 2010;65:2285-90

Patel N, et al. Identification of optimal renal dosage adjustments for traditional and extended-infusion piperacillin-tazobactam dosing regimens in hospitalized patients. Antimicrob Agents Chemother 2010;54:460-5

Revilla N, et al. Vancomycin dosing assessment in intensive care unit patients based on a population pharmacokinetic/pharmacodynamic simulation. Br J Clin Pharmacol 2010;70:201-12

Roberts JA, et al. First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis. Int J Antimicrob Agents 2010;35:156-63

Samtani MN, et al. Pharmacokinetic-pharmacodynamic-model-guided doripenem dosing in critically ill patients. Antimicrob Agents Chemother 2010;54:2360-2364

Shaw PA. Combination versus monotherapy for septic shock patients. Crit Care Med 2010;38:1905-6

van de Vijsel LM, et al. Initial vancomycin dosing recommendations for critically ill patients undergoing continuous venovenous hemodialysis. Can J Hosp Pharm 2010;63:196-206

Xamplas RC, et al. Implementation of an extended-infusion piperacillin-tazobactam program at an urban teaching hospital. Am J Health Syst Pharm 2010;67:622-8

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Stewardship: Microbiology

(Use of antibiograms, reporting of antibiotic susceptibility testing, use of rapid viral testing, use of rapid diagnostic testing in addition to cultures, procalcitonin [PCT testing], use of nonculture-based fungal markers in patients with hematologic malignancy)

2016
2015
2014
2013
2012
2011
2010

2016

Banerjee R, Humphries R. Clinical and laboratory considerations for the rapid detection of carbapenem-resistant Enterobacteriaceae. Virulence 2016 May 11:1-13

Brady AC, Lewis JS 2nd, Pfeiffer CD. Rapid detection of bla(OXA) in carbapenem-susceptible Acinetobacter radioresistens bacteremia leading to unnecessary antimicrobial administration. Diagn Microbiol Infect Dis 2016 (published online May 5)

Brennan MB, Osterby K, Schulz L, et al. Impact of low procalcitonin results on antibiotic administration in hospitalized patients at a tertiary care center. Infect Dis Ther 2016 (published online Jun 1)

Brink AJ, Van Wyk J, Moodley VM, et al. The role of appropriate diagnostic testing in acute respiratory tract infections: an antibiotic stewardship strategy to minimise diagnostic uncertainty in primary care. S Afr Med J 2016 May 10;106(6):554-61

de Jong E, van Oers JA, Beishuizen A, et al. Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial. Lancet Infect Dis 2016 Feb 29;16(7):819-27

Downes KJ, Weiss SL, Gerber JS, et al.; Centers for Disease Control and Prevention Epicenters Program. A pragmatic biomarker-driven algorithm to guide antibiotic use in the pediatric intensive care unit: the optimizing antibiotic strategies in Sepsis (OASIS) study. J Pediatric Infect Dis Soc 2016 (published online May 4)

Heil EL, Johnson JK. Impact of CLSI breakpoint changes on microbiology laboratories and antimicrobial stewardship programs. J Clin Microbiol 2016 Apr;54(4):840-4

Hohn A, Heising B, Schutte JK, et al. Procalcitonin-guided antibiotic treatment in critically ill patients. Langenbecks Arch Surg 2016 (published online Jun 10)

Humphries RM, Dien Bard J. Point-counterpoint: reflex cultures reduce laboratory workload and improve antimicrobial stewardship in patients suspected of having urinary tract infections. J Clin Microbiol 2016 Feb;54(2):254-8

Khosla R, Khosla SG, Becker KL, et al. Pleural fluid procalcitonin to distinguish infectious from noninfectious etiologies of pleural effusions. J Hosp Med 2016 May;11(5):363-5

Koncelik DL, Hernandez J. The impact of implementation of rapid QuickFISH testing for detection of Coagulase-Negative Staphylococci at a community-based hospital. Am J Clin Pathol 2016 Jan;145(1):69-74

Liang B, Wheeler JS, Blanchette LM. Impact of combination antibiogram and related education on inpatient fluoroquinolone prescribing patterns for patients with health care-associated Pneumonia. Ann Pharmacother 2016 Mar;50(3):172-9

Lockwood AM, Perez KK, Musick WL,et al. Integrating rapid diagnostics and antimicrobial stewardship in two community hospitals improved process measures and antibiotic adjustment time. Infect Control Hosp Epidemiol 2016 Apr;37(4):425-32

MacVane SH, Hurst JM, Boger MS, et al. Impact of a rapid multiplex polymerase chain reaction blood culture identification technology on outcomes in patients with vancomycin-resistant Enterococcal bacteremia. Infect Dis (Lond) 2016 May 19:1-6

Malcolmson C, Ng K, Hughes S, et al. Impact of matrix-assisted laser desorption and ionization time-of-flight and antimicrobial stewardship intervention on treatment of bloodstream infections in hospitalized children. J Pediatric Infect Dis Soc 2016 (published Jun 23)

Pardo J, Klinker KP, Borgert SJ, et al. Clinical and economic impact of antimicrobial stewardship interventions with the FilmArray blood culture identification panel. Diagn Microbiol Infect Dis 2016 Feb;84(2):159-64

Ray ST, Drew RJ, Hardiman F, et al. Rapid identification of microorganisms by filmArray blood culture identification panel improves clinical management in children. Pediatr Infect Dis J 2016 May;35(5):e134-8

Riedel S, Carroll KC. Early identification and treatment of pathogens in sepsis: molecular diagnostics and antibiotic choice. Clin Chest Med 2016 Jun;37(2):191-207

Scerbo MH, Kaplan HB, Dua A, et al. Beyond blood culture and gram stain analysis: A review of molecular techniques for the early detection of bacteremia in surgical patients. Surg Infect (Larchmt) 2016 Jun;17(3):294-302

Schoepp NG, Khorosheva EM, Schlappi TS, et al. Digital quantification of DNA replication and chromosome segregation enables determination of antimicrobial susceptibility after only 15 minutes of antibiotic exposure. Angew Chem Int Ed Engl 2016 (published online Jun 30)

van der Does Y, Rood PP, Haagsma JA, et al. Procalcitonin-guided therapy for the initiation of antibiotics in the ED: a systematic review. Am J Emerg Med 2016 Jul;34(7):1286-93

Verroken A, Defourny L, le Polain de Waroux O, et al. Clinical impact of MALDI-TOF MS identification and rapid susceptibility testing on adequate antimicrobial treatment in Sepsis with positive blood cultures. PLoS One 2016 May;11(5):e0156299

Walker T, Dumadag S, Lee CJ, et al. Clinical impact of laboratory implementation of Verigene BC-GN microarray-based assay for detection of gram-negative bacteria in positive blood cultures. J Clin Microbiol 2016 Jul;54(7):1789-96

Wenzler E, Goff DA, Mangino JE, et al. Impact of rapid identification of Acinetobacter Baumannii via matrix-assisted laser desorption ionization time-of-flight mass spectrometry combined with antimicrobial stewardship in patients with pneumonia and/or bacteremia. Diagn Microbiol Infect Dis 2016 Jan;84(1):63-8

Wenzler E, Wong JR, Goff DA, et al. Controversies in antimicrobial stewardship: focus on new rapid diagnostic technologies and antimicrobials. Antibiotics (Basel) 2016 Jan 14;5(1)

Wu CT, Chen CL, Lee HY, et al. Decreased antimicrobial resistance and defined daily doses after implementation of a clinical culture-guided antimicrobial stewardship program in a local hospital. J Microbiol Immunol Infect 2016 (published online Jan 22)

Yee C, Suarthana E, Dendukuri N, et al. Evaluating the impact of the multiplex respiratory virus panel polymerase chain reaction test on the clinical management of suspected respiratory viral infections in adult patients in a hospital setting. Am J Infect Control 2016 (published online Jun 13)

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2015

Aitken SL, Hemmige VS, Koo HL, et al. Real-world performance of a microarray-based rapid diagnostic for gram-positive bloodstream infections and potential utility for antimicrobial stewardship. Diagn Microbiol Infect Dis 2015 Jan;81(1):4-8

Albrich WC, Harbarth S. Pros and cons of using biomarkers versus clinical decisions in start and stop decisions for antibiotics in the critical care setting. Intensive Care Med 2015 Oct;41(10):1739-51

Al-Tawfiq JA, Momattin H, Al-Habboubi F, et al. Restrictive reporting of selected antimicrobial susceptibilities influences clinical prescribing. J Infect Public Health 2015 May-Jun;8(3):234-41

Bauer KA, Goff DA. When diagnostic technology is ahead of the hospital budget: what is antimicrobial stewardship to do? Clin Infect Dis 2015 Aug 1;61(3):486-7

Bielicki JA, Sharland M, Johnson AP, et al. Selecting appropriate empirical antibiotic regimens for paediatric bloodstream infections: application of a Bayesian decision model to local and pooled antimicrobial resistance surveillance data. J Antimicrob Chemother 2015 (published online Nov 30)

Boyles TH, Davis K, Crede T, et al. Blood cultures taken from patients attending emergency departments in South Africa are an important antibiotic stewardship tool, which directly influences patient management. BMC Infect Dis 2015 Oct 6;15:410

Box MJ, Sullivan EL, Ortwine KN, et al. Outcomes of rapid identification for gram-positive bacteremia in combination with antibiotic stewardship at a community-based hospital system. Pharmacotherapy 2015 Mar;35(3):269-76

Brechot N, Hekimian G, Chastre J, et al. Procalcitonin to guide antibiotic therapy in the ICU. Int J Antimicrob Agents 2015 Dec;46(Suppl 1):S19-24

Coorevits L, Boelens J, Claeys G. Direct susceptibility testing by disk diffusion on clinical samples: a rapid and accurate tool for antibiotic stewardship. Eur J Clin Microbiol Infect Dis 2015 Jun;34(6):1207-12

Hill JN, Suda KJ, Ramanathan S, et al. Development of a unit-specific antibiogram and planning for implementation: Preimplementation findings. Am J Infect Control 2015 Nov 1;43(11):1264-7

Holm A, Cordoba G, Sorensen TM, et al. Point of care susceptibility testing in primary care — does it lead to a more appropriate prescription of antibiotics in patients with uncomplicated urinary tract infections? Protocol for a randomized controlled trial. BMC Fam Pract 2015 Aug 21;16:106

Hohn A, Heising B, Hertel S, et al. Antibiotic consumption after implementation of a procalcitonin-guided antimicrobial stewardship programme in surgical patients admitted to an intensive care unit: a retrospective before-and-after analysis. Infection 2015 Aug;43(4):405-12

Klepser ME, Adams AJ, Klepser DG. Antimicrobial stewardship in outpatient settings: leveraging innovative physician-pharmacist collaborations to reduce antibiotic resistance. Health Secur 2015 May-Jun;13(3):166-73

Meili M, Muller B, Kulkarni P, et al. Management of patients with respiratory infections in primary care: procalcitonin, C-reactive protein or both? Expert Rev Respir Med 2015 Oct;9(5):587-601

Mertz D, Brooks A, Irfan N, et al. Antimicrobial stewardship in the intensive care setting — a review and critical appraisal of the literature. Swiss Med Wkly 2015 Dec 21;145:w14220

Mwaigwisya S, Assiri RA, O'Grady J. Emerging commercial molecular tests for the diagnosis of bloodstream infection. Expert Rev Mol Diagn 2015 May;15(5):681-92

Pardo J, Klinker KP, Borgert SJ, et al. Clinical and economic impact of antimicrobial stewardship interventions with the FilmArray blood culture identification panel. Diagn Microbiol Infect Dis 2015 (published online Oct 29)

Schuetz P, Aujesky D, Muller C, et al. Biomarker-guided personalised emergency medicine for all — hope for another hype? Swiss Med Wkly 2015 Feb 19;145:w14079

Schuetz P, Balk R, Briel M, et al. Economic evaluation of procalcitonin-guided antibiotic therapy in acute respiratory infections: a US health system perspective. Clin Chem Lab Med 2015 Mar;53(4):583-92

Sothoron C, Ferreira J, Guzman N, et al. A stewardship approach to optimize antimicrobial therapy through use of a rapid microarray assay on blood cultures positive for gram-negative bacteria. J Clin Microbiol 2015 Nov;53(11):3627-9

Southern TR, VanSchooneveld TC, Bannister DL, et al. Implementation and performance of the BioFire FilmArray blood culture identification panel with antimicrobial treatment recommendations for bloodstream infections at a Midwestern academic tertiary hospital. Diagn Microbiol Infect Dis 2015 Feb;81(2):96-101

Timbrook T, Maxam M, Bosso J. Antibiotic discontinuation rates associated with positive respiratory viral panel and low procalcitonin results in proven or suspected respiratory infections. Infect Dis Ther 2015 Sep;4(3):297-306

Warhurst G, Dunn G, Chadwick P, et al. Rapid detection of health-care-associated bloodstream infection in critical care using multipathogen real-time polymerase chain reaction technology: a diagnostic accuracy study and systematic review. Health Technol Assess 2015 May;19(35)

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2014

Aitken SL, Beyda ND, Shah DN, et al. Clinical practice patterns in hospitalized patients at risk for invasive candidiasis: role of antifungal stewardship programs in an era of rapid diagnostics. Ann Pharmacother 2014 Jun;48(6):683-90

Avdic E, Carroll KC. The role of the microbiology laboratory in antimicrobial stewardship programs. Infect Dis Clin North Am 2014 Jun;28(2):215-35

Barraud O, Francois B, Chainier D, et al. Value of integron detection for predicting antibiotic resistance in patients with gram-negative septicaemia. Int J Antimicrob Agents 2014 Oct;44(4):351-3

Bauer KA, Perez KK, Forrest GN, et al. Review of rapid diagnostic tests used by antimicrobial stewardship programs. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S134-45

Branda JA, Lewandrowski K. Utilization management in microbiology. Clin Chim Acta 2014 Jan 1;427:173-7

Crandon JL, MacVane SH, Nicolau DP. Clinical laboratory-based assay methodologies may underestimate and increase variability of vancomycin protein binding in hospitalized patients. Pharmacotherapy 2014 Feb;34(2):203-9

Hill JT, Tran KD, Barton KL, et al. Evaluation of the nanosphere Verigene BC-GN assay for direct identification of gram-negative bacilli and antibiotic resistance markers from positive blood cultures and potential impact for more-rapid antibiotic interventions. J Clin Microbiol 2014 Oct;52(10):3805-7

Housman ST, Sutherland CA, Nicolau DP. Pharmacodynamic profile of commonly utilised parenteral therapies against meticillin-susceptible and meticillin-resistant Staphylococcus aureus collected from US hospitals. Int J Antimicrob Anents 2014 Sep;44(3):235-41

Jain JG, Housman ST, Nicolau DP. Humanized tissue pharmacodynamics of cefazolin against commonly isolated pathogens in skin and skin structure infections. J Antimicrob Chemother 2014 Sep;69(9):2443-7

Koser CU, Ellington MJ, Peacock SJ. Whole-genome sequencing to control antimicrobial resistance. Trends Genet 2014 Sep;30(9):401-7

Kothari A, Morgan M, Haake DA. Emerging technologies for rapid identification of bloodstream pathogens. Clin Infect Dis 2014 Jul 15;59(2):272-8

Langsjoen J, Brady C, Obenauf E, et al. Nasal screening is useful in excluding methicillin-resistant Staphylococcus aureus in ventilator-associated pneumonia. Am J Infect Control 2014 Sep;42(9):1014-5

Lee LY, Korman TM, Graham M. Rapid time to results and high sensitivity of the CarbaNP test on early cultures. J Clin Microbiol 2014 Nov;52(11):4023-6

Leis JA, Rebick GW, Daneman N, et al. Reducing antimicrobial therapy for asymptomatic bacteriuria among noncatheterized inpatients: a proof-of-concept study. Clin Infect Dis 2014 Apr;58(7):980-3

MacFadden DR, Ridgway JP, Robicsek A, et al. Predictive utility of prior positive urine cultures. Clin Infect Dis 2014 Nov 1;59(9):1265-71

Machen A, Drake T, Wang YF. Same day identification and full panel antimicrobial susceptibility testing of bacteria from positive blood culture bottles made possible by a combined lysis-filtration method with MALDI-TOF VITEK mass spectrometry and the VITEK2 system. PLoS One 2014 Feb 14;9(2):e87870

McCulloh RJ, Andrea S, Reinert S, et al. Potential utility of multiplex amplification respiratory viral panel testing in the management of acute respiratory infection in children: a retrospective analysis. J Pediatric Infect Dis Soc 2014 Jun;3(2):146-53

Meisner M. Update on procalcitonin measurements. Ann lab Med 2014 Jul;34(4):263-73

Nagel JL, Huang AM, Kunapuli A, et al. Impact of antimicrobial stewardship intervention on coagulase-negative Staphylococcus blood cultures in conjunction with rapid diagnostic testing. J Clin Microbiol 2014 Aug;52(8):2849-54

Pardo J, Klinker KP, Borgert SJ, et al. Time to positivity of blood cultures supports antibiotic de-escalation at 48 hours. Ann Pharmacother 2014 Jan;48(1):33-40

Peppard WJ, Ledeboer NA. Implementation of polymerase chain reaction to rule out Clostridium difficile infection is associated with reduced empiric antibiotic duration of therapy. Hosp Pharm 2014 Jul;49(7):639-43

Perez KK, Olsen RJ, Musick WL, et al. Integrating rapid diagnostics and antimicrobial stewardship improves outcomes in patients with antibiotic-resistant gram-negative bacteremia. J Infect 2014 Sep;69(3):216-25

Prescott JF. The resistance tsunami, antimicrobial stewardship, and the golden age of microbiology. Vet Microbiol 2014 Jul 16;171(3-4):273-8

Salluh JI, Nobre V, Povoa P. Using procalcitonin to guide antimicrobial duration in sepsis: asking the same questions will not bring different answers. Crit Care 2014 May 13;18(3):142

Schuetz P, Kutz A, Grolimund E, et al. Excluding infection through procalcitonin testing improves outcomes of congestive heart failure patients presenting with acute respiratory symptoms: results from the randomized ProHOSP trial. Int J Cardiol 2014 Aug 20;175(3):464-72

Shehabi Y, Sterba M, Garrett PM, et al. Procalcitonin algorithm in critically ill adults with undifferentiated infection or suspected sepsis. a randomized controlled trial. Am J Respir Crit Care Med 2014 Nov 15;190(10):1102-10

So W, Crandon JL, Zhanel GG, et al. Comparison of in vivo and in vitro pharmacodynamics of a humanized regimen of 600 milligrams of ceftaroline fosamil every 12 hours against Staphylococcus aureus at initial inocula of 106 and 108 CFU per milliliter. Antimicrob Agent Chemother 2014 Nov;58(11)6931-3

Terp S, Krishnadasan A, Bowen W, et al. Introduction of rapid methicillin-resistant Staphylococcus aureus polymerase chain reaction testing and antibiotic selection among hospitalized patients with purulent skin infections. Clin Infect Dis 2014 Apr;58(8):e129-32

Tuite N, Reddington K, Barry T, et al. Rapid nucleic acid diagnostics for the detection of antimicrobial resistance in gram-negative bacteria: is it time for a paradigm shift? J Antimicrob Chemother 2014 Jul;69(7):1729-33

Vazquez Melendez EL, Farrell JJ, Hujer AM, et al. Culture negative empyema in a critically ill child: an opportunity for rapid molecular diagnostics. BMC Anesthesiol 2014 Nov 22;14:107

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2013

Coupat C, et al. Selective reporting of antibiotic susceptibility data improves the appropriateness of intended antibiotic prescriptions in urinary tract infections: a case-vignette randomised study. Eur J Clin Microbiol Infect Dis 2013 May;32(5):627-36

Dhiman N, et al. Evaluation of the BinaxNOW Staphylococcus aureus test for rapid identification of Gram-positive cocci from VersaTREK blood culture bottles. J Clin Microbiol 2013 Sep;51(9):2939-42

Dudley MN, et al. Background and rationale for revised Clinical and Laboratory Standards Institute interpretive criteria (Breakpoints) for Enterobacteriaceae and Pseudomonas aeruginosa: I. Cephalosporins and Aztreonam. Clin Infect Dis 2013;56:1301-9

Farrell JJ, et al. "Salvage microbiology": detection of bacteria directly from clinical specimens following initiation of antimicrobial treatment. PLoS One 2013;8(6):e66349

Gawronski, KM, et al. A stewardship program's retrospective evaluation of vancomycin AIC24/MIC and time to microbiological clearance in patients with methicillin-resistant Staphylococcus aureus bacteremia and osteomyelitis. Clin Ther 2013 Jun;35(6):772-9

Geiger K, Brown J. Rapid testing for methicillin-resistant Staphylococcus aureus: implications for antimicrobial stewardship. Am J Health Syst Pharm 2013;70:335-42

Hombach M, et al. The critical influence of the intermediate category on interpretation errors in revised EUCAST and CLSI antimicrobial susceptibility testing guidelines. Clin Microbiol Infect 2013;19:E59-71

Huang AM, et al. Impact of rapid organism identification via matrix-assisted laser desorption/ionization time-of-flight combined with antimicrobial stewardship team intervention in adult patients with bacteremia and candidemia. Clin Infect Dis 2013 Nov;57(9):1237-45

McGregor JC, et al. Comparison of antibiograms developed for inpatients and primary care outpatients. Diagn Microbiol Infect Dis 2013 May;76(1):73-9

O'Brien DJ, et al. Maximizing the impact of antimicrobial stewardship: the role of diagnostics, national and international efforts. Curr Opin Infect Dis 2013 Aug;26(4):352-8

Patel R. Matrix-assisted laser desorption ionization-time of flight mass spectrometry in clinical microbiology. Clin Infect Dis 2013 Aug;57(4):564-72

Rimawi RH, et al. The impact of penicillin skin testing on clinical practice and antimicrobial stewardship. J Hosp Med 2013 Jun;8(6):341-5

Sango A, et al. Stewardship approach for optimizing antimicrobial therapy through use of a rapid microarray assay on blood cultures positive for Enterococcus species. J Clin Microbiol 2013 Dec;51(12):4008-11

Schuetz P, et al. Using procalcitonin-guided algorithms to improve antimicrobial therapy in ICU patients with respiratory infections and sepsis. Curr Opin Crit Care 2013 Oct;19(5):453-60

Sridharan P, et al. The efficacy of procalcitonin as a biomarker in the management of sepsis: slaying dragons or tilting at windmills? Surg Infect (Larchmt) 2013 Dec;14(6):489-511

Trienski TL, et al. Evaluation and use of a rapid Staphylococcus aureus assay by an antimicrobial stewardship program. Am J Health Syst Pharm 2013 Nov 1;70(21):1908-12

van Belkum A, et al. Rapid clinical bacteriology and its future impact. Ann Lab Med 2013;33:14-27

Zadroga R, et al. Comparison of 2 blood culture media shows significant differences in bacterial recovery for patients on antimicrobial therapy. Clin Infect Dis 2013 Mar;56(6):790-7

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2012

Aldeyab MA, et al. An evaluation of the impact of antibiotic stewardship on reducing the use of high-risk antibiotics and its effect on the incidence of Clostridium difficile infection in hospital settings. J Antimicrob Chemother 2012;67:2988-96

Asin E, et al. Comparison of antimicrobial pharmacokinetic/pharmacodynamic breakpoints with EUCAST and CLSI clinical breakpoints for Gram-positive bacteria. Int J Antimicrob Agents 2012;40:313-22

Baron EJ, Tenover FC. Methicillin-resistant Staphylococcus aureus diagnostics: state of the art. Expert Opin Med Diagn 2012;6:585-92

Frye AM, et al. Clinical impact of a real-time PCR assay for rapid identification of staphylococcal bacteremia. J Clin Microbiol 2012;50:127-33

Goff DA, et al. Using rapid diagnostic tests to optimize antimicrobial selection in antimicrobial stewardship programs. Pharmacotherapy 2012;32:677-87

Heil EL, et al. Impact of a rapid peptide nucleic acid fluorescence in situ hybridization assay on treatment of candida infections. Am J Health Syst Pharm 2012;69:1910-4

Herbert C, et al. Demonstration of the weighted-incidence syndromic combination antibiogram: an empiric prescribing decision aid. Infect Control Hosp Epidemiol 2012;33:381-8

Katsios CM, et al. An antimicrobial stewardship program improves antimicrobial treatment by culture site and the quality of antimicrobial prescribing in critically ill patients. Critical Care 2012;16:R216

Kinnunen P, et al. Self-assembled magnetic bead biosensor for measuring bacterial growth and antimicrobial susceptibility testing. Small 2012;8:2477-82

Perez KK, et al. Integrating rapid pathogen identification and antimicrobial stewardship significantly decreases hospital costs. Arch Pathol Lab Med 2013 Sep;137(9):1247-54

Peter H, et al. Direct detection and genotyping of Klebsiella pneumoniae carbapenemases from urine by use of a new DNA microarray test. J Clin Microbiol 2012;50:3990-8

Riedel S. Procalcitonin and the role of biomarkers in the diagnosis and management of sepsis. Diagn Microbiol Infect Dis 2012;73:221-7

Schulz LT, et al. Can the antibiogram be used to assess microbiologic outcomes after antimicrobial stewardship interventions? A critical review of the literature. Pharmacotherapy 2012;32:668-76

van der Bij AK, et al. Clinical breakpoint changes and their impact on surveillance of antimicrobial resistance in Escherichia coli causing bacteraemia. Clin Microbiol Infect 2012;18:E466-72

Wong JR, et al. Antimicrobial stewardship pharmacist interventions for coagulase-negative staphylococci positive blood cultures using rapid polymerase chain reaction. Ann Pharmacother 2012;46:1484-90

Xu R, et al. Antibiogram compliance in University HealthSystem Consortium participating hospitals with Clinical and Laboratory Standards Institute guidelines. Am J Health Syst Pharm 2012;69:598- 606

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2011

Coghe F, et al. The role of the laboratory in choosing antibiotics. J Matern Fetal Neonatal Med 2011;24:18-20

Dhiman N, et al. Performance and cost analysis of matrix-assisted laser desorption ionization-time of flight mass spectrometry for routine identification of yeast. J Clin Microbiol 2011;49:1614-6

Holtzman C, et al. Assessment of impact of peptide nucleic acid fluorescence in situ hybridization for rapid identification of coagulase-negative staphylococci in the absence of antimicrobial stewardship intervention. J Clin Microbiol 2011 49:1581-2

Laakso S, et al. Evaluation of high-throughput PCR and microarray-based assay in conjunction with automated DNA extraction instruments for diagnosis of sepsis. PLoS One 2011;6:e26655

Liew YX, et al. Use of procalcitonin (PCT) to guide discontinuation of antibiotic use in an unspecified sepsis is an antimicrobial stewardship program (ASP). Eur J Clin Microbiol Infect Dis 2011;30:853-5.

Oliveira PR, et al. Impact of restriction of cefepime use on the antimicrobial susceptibility of Gram- negative bacilli related to healthcare-associated infections in an orthopedic hospital. Infect Drug Resist 2011;4:149-54

Pogue JM, et al. Role of unit-specific combination antibiograms for improving the selection of appropriate empiric therapy for Gram-negative pneumonia. Infect Control Hosp Epidemiol 2011;32:289-92

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2010

Bauer KA, et al. An antimicrobial stewardship program's impact with rapid polymerase chain reaction methicillin-resistant Staphylococcus aureus/S. aureus blood culture test in patients with S. aureus bacteremia. Clin Infect Dis 2010;51:1074-80

Bulik CC, et al. Comparison of meropenem MICs and susceptibilities for carbapenemase-producing Klebsiella pneumoniae isolates by various testing methods. J Clin Microbio 2010 Jul;48(7):2402-6

Parta M, et al. Impact of an assay that enables rapid determination of Staphylococcus species and their drug susceptibility on the treatment of patients with positive blood culture results. Infect Control Hosp Epidemiol 2010;31:1043-8

Tenover FC. Potential impact of rapid diagnostic tests on improving antimicrobial use. Ann N Y Acad Sci 2010;1213:70-80

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Stewardship: Measurement

(Overall measurement approaches [days of therapy vs. defined daily dose], measurements of expenditures, impact measurements)

2016
2015
2014
2013
2012
2011
2010

2016

Akpan MR, Ahmad R, Shebl NA, et al. A review of quality measures for assessing the impact of antimicrobial stewardship programs in hospitals. Antibiotics (Basel) 2016 Jan 13;5(1)

Anderson DJ, Juthani-Mehta M, Morgan DJ. Research methods in healthcare epidemiology and antimicrobial stewardship: Randomized controlled trials. Infect Control Hosp Epidemiol 2016 Jun;37(6):629-34

Borde JP, Nussbaum S, Hauser S, et al. Implementing an intensified antibiotic stewardship programme targeting daptomycin use in orthopaedic surgery: a cost-benefit analysis from the hospital perspective. Infection 2016 Jun;44(3):301-7

Dik JWH, Hendrix R, Poelman R, et al. Measuring the impact of antimicrobial stewardship programs. Expert Rev Anti Infect Ther 2016 Jun;14(6):569-75

Fodero KE, Horey AL, Krajewski MP, et al. Impact of an antimicrobial stewardship program on patient safety in veterans prescribed vancomycin. Clin Ther 2016 Mar;38(3):494-502

García-Martínez L, Gracia-Ahulfinger I, Machuca I, et al. Impact of the PROVAUR stewardship programme on linezolid resistance in a tertiary university hospital: a before-and-after interventional study. J Antimicrob Chemother 2016 (published online May 30)

Karanika S, Paudel S, Grigoras C, et al. Clinical and economic outcomes from the implementation of hospital-based antimicrobial stewardship programs: a systematic review and meta-analysis. Antimicrob Agents Chemother 2016 (published online May 31)

Le Coz P, Carlet J, Roblot F, et al. Human resources needed to perform antimicrobial stewardship teams' activities in French hospitals. Med Mal Infect 2016 Jun;46(4):200-6

Lynch JB. Promoting value through antimicrobial stewardship. Healthc Financ Manage 2016 Mar;70(3):38-41

Morgan DJ, Safdar N, Milstone AM, et al. Research methods in healthcare epidemiology and antimicrobial stewardship. Infect Control Hosp Epidemiol 2016 Jun;37(6):627-8

Murri R, de Belvis AG, Fantoni M, et al.; collaborative SPES Group. Impact of antibiotic stewardship on perioperative antimicrobial prophylaxis. Int J Qual Health Care 2016 Jun 9

Nguyen-Ha PT, Howrie D, Crowley K, et al. A quality assessment of a collaborative model of a pediatric antimicrobial stewardship program. Pediatrics 2016 Apr;137(4):e20150316

Okumura LM, Riveros BS, Gomes-da-Silva MM, et al. A cost-effectiveness analysis of two different antimicrobial stewardship programs. Braz J Infect Dis 2016 May-Jun;20(3):255-61

Schuts EC, Hulscher ME, Mouton JW, et al. Current evidence on hospital antimicrobial stewardship objectives: a systematic review and meta-analysis. Lancet Infect Dis 2016 (published online Mar 2)

Schweizer ML, Braun BI, Milstone AM. Research methods in healthcare epidemiology and antimicrobial stewardship-quasi-experimental designs. Infect Control Hosp Epidemiol 2016 (published online Jun 7)

Snyder GM, Young H, Varman M, et al. Research methods in healthcare epidemiology and antimicrobial stewardship-observational studies. Infect Control Hosp Epidemiol 2016 Jun 20;37(6):627-8

Tabah A, Cotta MO, Garnacho-Montero J, et al.; Working Group for Antimicrobial Use in the ICU. A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the intensive care unit. Clin Infect Dis 2016 Apr 15;62(8):1009-17

Tan C, Ritchie M, Alldred J, et al. Validating hospital antibiotic purchasing data as a metric of inpatient antibiotic use. J Antimicrob Chemother 2016 Feb;71(2):547-53

Vercheval C, Gillet M, Maes N, et al. Quality of documentation on antibiotic therapy in medical records: evaluation of combined interventions in a teaching hospital by repeated point prevalence survey. Eur J Clin Microbiol Infect Dis 2016 (published online Jun 2)

Zachariah P, Newland JG, Gerber JS, et al.; SHARPS Collaborative Project Group. Costs of antimicrobial stewardship programs at US children's hospitals. Infect Control Hosp Epidemiol 2016 Mar 29:1-3

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2015

Boel J, Sogaard M, Andreasen V, et al. Evaluating antibiotic stewardship programs in patients with bacteremia using administrative data: a cohort study. Eur J Clin Microbiol Infect Dis 2015 Jul;34(7):1475-84

Chowers M, Carmeli Y, Shitrit P, et al. Cost analysis of an intervention to prevent methicillin-resistant Staphylococcus aureus (MRSA) transmission. PLoS One 2015 Sep 25;10(9):e0138999

Coulter S, Merollini K, Roberts JA, et al. The need for cost-effectiveness analyses of antimicrobial stewardship programmes: a structured review. Int J Antimicrob Agents 2015 Aug;46(2):140-9

Dik JW, Hendrix R, Friedrich AW, et al. Cost-minimization model of a multidisciplinary antibiotic stewardship team based on a successful implementation on a urology ward of an academic hospital. PLoS One 2015 May 8;10(5):e0126106

Dik JW, Vemer P, Friedrich AW, et al. Financial evaluations of antibiotic stewardship programs-a systematic review. Front Microbiol 2015 Apr 16;6:317

Del Arco A, Tortajada B, de la Torre J, et al. The impact of an antimicrobial stewardship programme on the use of antimicrobials and the evolution of drug resistance. Eur J Clin Microbiol Infect Dis 2015 Feb;34(2):247-51

Drekonja DM, Filice GA, Greer N, et al. Antimicrobial stewardship in outpatient settings: a systematic review. Infect Control Hosp Epidemiol 2015 Feb;36(2):142-52

Evans SR, Rubin D, Follmann D, et al. Desirability of outcome ranking (DOOR) and response adjusted for duration of antibiotic risk (RADAR). Clin Infect Dis 2015 Sep 1;61(5):800-6

Jenkins TC, Knepper BC, Shihadeh K, et al. Long-term outcomes of an antimicrobial stewardship program implemented in a hospital with low baseline antibiotic use. Infect Control Hosp Epidemiol 2015 Jun;36(6):664-72

Lambert ML, Bruyndonckx R, Goossens H, et al. The Belgian policy of funding antimicrobial stewardship in hospitals and trends of selected quality indicators for antimicrobial use, 1999-2010: a longitudinal study. BMJ Open 2015 Feb 13;5(2):e006916

Loo LW, Liew YX, Lee W, et al. Impact of antimicrobial stewardship program (ASP) on outcomes in patients with acute bacterial skin and skin structure infections (ABSSSIs) in an acute-tertiary care hospital. Infect Dis Ther 2015 Sep;4(Suppl 1):15-25

Madaras-Kelly K, Jones M, Remington R, et al. Description and validation of a spectrum score method to measure antimicrobial de-escalation in healthcare associated pneumonia from electronic medical records data. BMC Infect Dis 2015 Apr 25;15:197

Maeda M, Takuma T, Seki H, et al. Effect of interventions by an antimicrobial stewardship team on clinical course and economic outcome in patients with bloodstream infection. J Infect Chemother 2015 (published online Dec 9)

Munoz P, Valerio M, Vena A, et al. Antifungal stewardship in daily practice and health economic implications. Mycoses 2015 Jun;58 Suppl 2:14-25

Pakyz AL, Moczygemba LR, Wang H, et al. An evaluation of the association between an antimicrobial stewardship score and antimicrobial usage. J Antimicrob Chemother 2015 May;70(5):1588-91

Smith MJ, Gerber JS, Hersh AL. Inpatient antimicrobial stewardship in pediatrics: a systematic review. J Pediatric Infect Dis Soc 2015 Dec;4(4):e127-35

van den Bosch CM, Geerlings SE, Natsch S, et al. Quality indicators to measure appropriate antibiotic use in hospitalized adults. Clin Infect Dis 2015 Jan 15;60(2):281-91

You J. Antimicrobial stewardship programs - cost-minimizing or cost-effective? Expert Opin Pharmacother 2015 Feb;16(2):155-7

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2014

Aldeyab MA, McElnay JC, Scott MG, et al. A modified method for measuring antibiotic use in healthcare settings: implications for antibiotic stewardship and benchmarking. J Antimicrob Chemother 2014 Apr;69(4):1132-41

Bansal D, Mangla S, Undela K, et al. Measurement of adult antimicrobial drug use in tertiary care hospital using defined daily dose and days of therapy. Indian J Pharm Sci 2014 May;76(3):211-7

Burnpass JB, McDaneld PM, DePestel DD, et al. Outcomes and metrics for antimicrobial stewardship: survey of physicians and pharmacists. Clin Infect Dis 2014 Oct 15;59 Suppl 3:S108-11

DePestel DD, Eiland EH 3rd, Lusardi K, et al. Assessing appropriateness of antimicrobial therapy: in the eye of the interpreter. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S154-61

Dodds Ashley ES, Kaye KS, DePestel DD, et al. Antimicrobial stewardship: philosophy versus practice. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S112-21

Fukuda T, Watanabe H, Ido S, et al. Contribution of antimicrobial stewardship programs to reduction of antimicrobial therapy costs in community hospital with 429 beds-before-after comparative two-year trial in Japan. J Pharm Policy Pract 2014 Aug 5;7(1):10

Guillot J, Lebel D, Roy H, et al. Usefulness of defined daily dose and days of therapy in pediatrics and obstetrics-gynecology: a comparative analysis of antifungal drugs (2000-2001, 2005-2006, and 2010-2011). J Pediatr Pharmacol Ther 2014 Jul;19(3):196-201

Hermsen ED, McDaneld PM, Eiland ED 3rd, et al. Breaking down the barriers: challenges with development and implementation of an industry-sponsored antimicrobial stewardship data collection and analysis tool. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S179-84

Ibrahim OM, Polk RE. Antimicrobial use metrics and benchmarking to improve stewardship outcomes: methodology, opportunities, and challenges. Infect Dis Clin North Am 2014 Jun;28(2):195-214

Lee TC, Frenette C, Jayaraman D, et al. Antibiotic self-stewardship: trainee-led structured antibiotic time-outs to improve antimicrobial use. Ann Intern Med 2014 Nov 18;161(10 Suppl):S53-8

McGregor JC, Furuno JP. Optimizing research methods used for the evaluation of antimicrobial stewardship programs. Clin Infect Dis 2014 Oct 15;59(Suppl 3):S185-92

Morris AM. Antimicrobial stewardship programs: appropriate measures and metrics to study their impact. Curr Treat Options Infect Dis 2014;6(2):101-12

Seah XF, Ong YL, Tan SW, et al. Impact of an antimicrobial stewardship program on the use of carbapenems in a tertiary women's and children's hospital, Singapore. Pharmacotherapy 2014 Nov;34(11):1141-50

Septimus E. Antimicrobial stewardship-qualitative and quantitative outcomes: the role of measurement. Curr Infect Dis Rep 2014 Nov;16(11):433

Van den Bosch CM, Hulscher ME, Natsch S, et al. Development of quality indicators for antimicrobial treatment in adults with sepsis. BMC Infect Dis 2014 Jun 20;14:345

Yu K, Rho J, Morcos, M, et al. Evaluation of dedicated infectious diseases pharmacists on antimicrobial stewardship teams. Am J Health Syst Pharm 2014 Jun 15;71(12):1019-28

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2013

Antworth A, et al. Impact of an antimicrobial stewardship program comprehensive care bundle on management of candidemia. Pharmacotherapy 2013;33:137-143

Bassi J, et al. Measuring value for money: a scoping review on economic evaluation of health information systems. J Am Med Inform Assoc 2013 Jul-Aug;20(4):792-801

Cappelletty D, et al. Evaluating the impact of a pharmacist's absence from an antimicrobial stewardship team. Am J Health Syst Pharm 2013 Jun 15;70(12):1065-9

Chung GW, et al. Antimicrobial stewardship: a review of prospective audit and feedback systems and an objective evaluation of outcomes. Virulence 2013;4:151-7

Gravatt LA, et al. Challenges in measuring antibiotic consumption. Curr Infect Dis Rep 2013 Dec;15(6):559-63

Hawn MT, et al. Timing of surgical antibiotic prophylaxis and the risk of surgical site infection. JAMA Surg 2013 Jul;148(7):649-57

Hong SY, et al. Evaluation of programmatic changes to an antimicrobial stewardship program with house officer feedback. J Eval Clin Pract 2013;19:388-92

Lin YS, et al. Impact of an antimicrobial stewardship program with multidisciplinary cooperation in a community public teaching hospital in Taiwan. Am J Infect Control 2013 Nov;41(11):1069-72

Malani AN, et al. Clinical and economic outcomes from a community hospital's antimicrobial stewardship program. Am J Infect Control 2013;41:145-148

Mohammadi S, et al. Clinical outcomes of a Veterans Affairs outpatient antimicrobial treatment program. South Med J 2013 Jun;106(6):345-9

Retamar P, et al. Evaluating the quality of antimicrobial prescribing: is standardisation possible? Enferm Infecc Microbiol Clin 2013 Sep;31(Suppl 4):25-30

Rimawi RH, et al. Impact of regular collaboration between infectious diseases and critical care practitioners on antimicrobial utilization and patient outcome. Crit Care Med 2013 Sep;41(9):2099-107

Sick AC, et al. Sustained savings from a longitudinal cost analysis of an internet-based preapproval antimicrobial stewardship program. Infect Control Hosp Epidemiol 2013;34:573-80

Suda KJ, et al. A national evaluation of antibiotic expenditures by healthcare setting in the United States, 2009. J Antimicrob Chemother 2013 Mar;68(3):715-8

Ullman MA, et al. The economic impact of starting, stopping, and restarting an antibiotic stewardship program: a 14-year experience. Antibiotics (Basel) 2013 Apr 24;2(2):256-64

Vettese N, et al. Outcomes associated with a thrice-weekly antimicrobial stewardship programme in a 253-bed community hospital. J Clin Pharm Ther 2013 Oct;38(5):401-4

Willmann M, et al. Time series analysis as a tool to predict the impact of antimicrobial restriction in antibiotic stewardship programs using the example of multidrug-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother 2013;57:1797-803

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2012

Beardsley JR, et al. Show me the money: long-term financial impact of an antimicrobial stewardship program. Infect Control Hosp Epidemiol 2012;33:398-400

Duszynska W, et al. Continuous infusion of piperacillin/tazobactam in ventilator-associated pneumonia: a pilot study on efficacy and costs. Int J Antimicrob Agents 2012;39:153-8

Griffith M, et al. Antimicrobial stewardship programs: methods of operation and suggested outcomes. Expert Rev Anti Infect Ther 2012;10:63-73

Hamblin S, et al. Prevention of adverse drug events and cost savings associated with PharmD interventions in an academic Level I trauma center: an evidence-based approach. J Trauma Acute Care Surg 2012;73:1484-90

Hübner C, et al. Cost-analysis of PCR-guided pre-emptive antibiotic treatment of Staphylococcus aureus infections: an analytic decision model. Eur J Clin Microbiol Infect Dis 2012;31:3065-72

Ibrahim OM, Polk RE. Benchmarking antimicrobial drug use in hospitals. Expert Rev Anti Infect Ther 2012;10:445-57

Khadem TM, et al. Antimicrobial stewardship: a matter of process or outcome? Pharmacotherapy 2012;32:688-706.

Magedanz L, et al. Impact of the pharmacist on a multidisciplinary team in an antimicrobial stewardship program: a quasi-experimental study. Int J Clin Pharm 2012;34:290-4

Manns B, et al. Evaluating the impact of a novel restricted reimbursement policy for quinolone antibiotics: a time series analysis. BMC Health Serv Res 2012;12:290

McGowan JE. Antimicrobial stewardship — the state of the art in 2011: focus on outcome and methods. Infect Control Hosp Epidemiol 2012;33:331-7

Morris AM, et al. Use of a structured panel process to define quality metrics for antimicrobial stewardship programs. Infect Control Hosp Epidemiol 2012 May;33(5):500-6

Neidell MJ, et al. Costs of healthcare- and community-associated infections with antimicrobial- resistant versus antimicrobial-susceptible organisms. Clin Infect Dis 2012;55:807-15

Niwa T, et al. Outcome measurement of extensive implementation of antimicrobial stewardship in patients receiving intravenous antibiotics in a Japanese university hospital. Int J Clin Pract 2012;66:999-1008

Nowak MA, et al. Clinical and economic outcomes of a prospective antimicrobial stewardship program. Am J Health Syst Pharm 2012;69:1500-8

Slekovec C, et al. Impact of a region wide antimicrobial stewardship guideline on urinary tract infection prescription patterns. Int J Clin Pharm 2012;34:325-9

Standiford HC, et al. Antimicrobial stewardship at a large tertiary care academic medical center: cost analysis before, during, and after a 7-year program. Infect Control Hosp Epidemiol 2012 Apr;33(4):338-45

Stevenson KB, et al. The economics of antimicrobial stewardship: the current state of the art and applying the business case model. Infect Control Hosp Epidemiol 2012 Apr;33(4):389-97

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2011

Altunsoy A, et al. The impact of a nationwide antibiotic restriction program on antibiotic usage and resistance against nosocomial pathogens in Turkey. Int J Med Sci 2011;8:339-44

Dumartin C, et al. Antibiotic stewardship programmes: legal framework and structure and process indicator in Southwestern French hospitals, 2005-2008. J Hosp Infect 2011;77:123-8

Enoch DA, et al. Outcome for Gram-negative bacteraemia when following restrictive empirical antibiotic guidelines. QJM 2011;104:411-9

Goff DA. Antimicrobial stewardship: bridging the gap between quality care and cost. Curr Opin Infect Dis 2011;24:S11-20

Heintz BH, et al. Impact of a multidisciplinary team review of potential outpatient parenteral antimicrobial therapy prior to discharge from an academic medical center. Ann Pharmacother 2011;45:1329-37

Kaki R, et al. Impact of antimicrobial stewardship in critical care: a systematic review. J Antimicrob Chemother 2011;66:1223-30

McIntosh KA, et al. A quality improvement initiative to improve adherence to national guidelines for empiric management of community-acquired pneumonia in emergency departments. Int J Qual Health Care 2011;23:142-50

Nadeau MC, Kuti EL. Clinical and economic impact of intravenous to oral conversion therapy programs. Conn Med 2011;75:25-9

Slain D, et al. Impact of a multimodal antimicrobial stewardship program on Pseudomonas aeruginosa susceptibility and antimicrobial use in the intensive care unit setting. Crit Care Res Pract 2011;2011:416426

Talpaert MJ, et al. Impact of guidelines and enhanced antibiotic stewardship on reducing broad- spectrum antibiotic usage and its effect on incidence of Clostridium difficile infection. J Antimicrob Chemother 2011;66:2168-74

Thakkar K, et al. A quality improvement programme to increase compliance with an anti-infective prescribing policy. J Antimicrob Chemother 2011;66:1916-20

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2010

McGarry LJ, et al. Economic assessment of doripenem versus imipenem in the treatment of ventilator-associated pneumonia. J Med Econ 2010 Mar;13(1):142-7

Meyer E, et al. Impact of a change in antibiotic prophylaxis on total antibiotic use in a surgical intensive care unit. Infection 2010;38:19-24

Miyawaki K, et al. Impact of antimicrobial stewardship by infection control team in a Japanese teaching hospital. Yakugaku Zasshi 2010;130:1105-11

Rattanaumpawan P, et al. Effectiveness of drug use evaluation and antibiotic authorization on patients' clinical outcomes, antibiotic consumption, and antibiotic expenditures. Am J Infect Control 2010;38:38-43

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Stewardship: Special Populations

(Immunocompromised patients, residents of nursing homes and skilled nursing facilities, neonatal intensive care units, terminally ill patients)

2016
2015
2014
2013
2012
2011
2010

2016

Baker TM, Satlin MJ. The growing threat of multidrug-resistant Gram-negative infections in patients with hematologic malignancies. Leuk Lymphoma 2016 (published online Jun 24)

Beaulac K, Corcione S, Epstein L, et al. Antimicrobial stewardship in a long-term acute care hospital using offsite electronic medical record audit. Infect Control Hosp Epidemiol 2016 Apr;37(4):433-9

Brandt NJ, Heil E. Antimicrobial stewardship in the post-acute long-term care setting: case discussion and updates. J Gerontol Nurs 2016 Jul 1;42(7):10-4

Cowan RU, Kishan D, Walton AL, et al. Cleaning, resistant bacteria, and antibiotic prescribing in residential aged care facilities. Am J Infect Control 2016 Mar 1;44(3):e19-21

Ellis K, Rubal-Peace G, Chang V, et al. Antimicrobial stewardship for a geriatric behavioral health population. Antibiotics (Basel) 2016 Jan 19;5(1)

Fernandez J, Tandon P, Mensa J, et al. Antibiotic prophylaxis in cirrhosis: good and bad. Hepatology 2016 Jun;63(6):2019-31

Giannella M, Tedeschi S, Bartoletti M, et al. Prevention of infections in nursing homes: antibiotic prophylaxis versus infection control and antimicrobial stewardship measures. Expert Rev Anti Infect Ther 2016 Feb;14(2):219-30

Katz MJ, Roghmann MC. Healthcare-associated infections in the elderly: what's new. Curr Opin Infect Dis 2016 Aug;29(4):388-93

Kidd F, Dubourg D, Heller F, et al. Antimicrobial stewardship in long-term care facilities in Belgium: a questionnaire-based survey of nursing homes to evaluate initiatives and future developments. Antimicrob Resist Infect Control 2016 Mar 8;5:7

McMaughan DK, Nwaiwu O, Zhao H, et al. Impact of a decision-making aid for suspected urinary tract infections on antibiotic overuse in nursing homes. BMC Geriatr 2016 Apr 15;16(1):81

Morrill HJ, Mermel LA, Baier RR, et al. Antimicrobial stewardship in Rhode Island long-term care facilities: current standings and future opportunities. Infect Control Hosp Epidemiol 2016 May 17:1-4

Morrill HJ, Caffrey AR, Jump RL, et al. Antimicrobial stewardship in long-term care facilities: A call to action. J Am Med Dir Assoc 2016 Feb;17(2):183.e1-16

Mylotte JM. Antimicrobial stewardship in long-term care: metrics and risk adjustment. J Am Med Dir Assoc 2016 Jul;17(7):672.e13-8

Shipp KD, Chiang T, Karasick S, et al. Antibiotic stewardship challenges in a referral neonatal intensive care unit. Am J Perinatol 2016 Apr;33(5):518-24

Snyder GM, Patel PR, Kallen AJ, et al. Factors associated with the receipt of antimicrobials among chronic hemodialysis patients. Am J Infect Control 2016 (published online May 13)

So M, Yang DY, Bell C, et al. Solid organ transplant patients: are there opportunities for antimicrobial stewardship? Clin Transplant 2016 (published online Mar 18)

Wolf J, Sun Y, Tang L, et al. Antimicrobial stewardship barriers and goals in pediatric oncology and bone marrow transplantation: A survey of antimicrobial stewardship practitioners. Infect Control Hosp Epidemiol 2016 Mar;37(3):343-7

Yang M, Vleck K, Bellantoni M, et al. Telephone survey of infection-control and antibiotic stewardship practices in long-term care facilities in Maryland. J Am Med Dir Assoc 2016 Jun 1;17(6):491-4

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2015

Backus D. Antimicrobial therapy in long-term care: controversy, colonization, and criteria. Consult Pharm 2015 Sep;30(9):513-22

Beckett CL, Harbarth S, Huttner B. Special considerations of antibiotic prescription in the geriatric population. Clin Microbiol Infect 2015 Jan;21(1):3-9

Bedenic B, Beader N, Godic-Torkar K, et al. Nursing home as a reservoir of carbapenem-resistant Acinetobacter baumannii. Microb Drug Resist 2015 Jun;21(3):270-8

Burns K, Roche F, Donlon S. Healthcare-associated infections and antimicrobial use in long-term care facilities: the Irish experience with the HALT surveys. J Hosp Infect 2015 Apr;89(4):276-80

Cailes B, Vergnano S, Kortsalioudaki C, et al. The current and future roles of neonatal infection surveillance programmes in combating antimicrobial resistance. Early Hum Dev 2015 Nov;91(11):613-8

Campbell DJ, Brown FG, Craig JC, et al. Assessment of current practice and barriers to antimicrobial prophylaxis in peritoneal dialysis patients. Nephrol Dial Transplant 2015 (published online Apr 22)

Cantey JB, Wozniak PS, Sanchez PJ. Prospective surveillance of antibiotic use in the neonatal intensive care unit: results from the SCOUT study. Pediatr Infect Dis J 2015 Mar;34(3):267-72

Chopra T, Goldstein EJ. Clostridium difficile infection in long-term care facilities: a call to action for antimicrobial stewardship. Clin Infect Dis 2015 May 15;60(Suppl 2):S72-6

Cotten CM. Antibiotic stewardship: reassessment of guidelines for management of neonatal sepsis. Clin Perinatol 2015 Mar;42(1):195

Crnich CJ, Jump R, Trautner B, et al. Optimizing antibiotic stewardship in nursing homes: a narrative review and recommendations for improvement. Drugs Aging 2015 Sep;32(9):699-716

Daneman N, Bronskill SE, Gruneir A, et al. Variability in antibiotic use across nursing homes and the risk of antibiotic-related adverse outcomes for individual residents. JAMA Intern Med 2015 Aug;175(8):1331-9

Doernberg SB, Dudas V, Trivedi KK. Implementation of an antimicrobial stewardship program targeting residents with urinary tract infections in three community long-term care facilities: a quasi-experimental study using time-series analysis. Antimicrob Resist Infect Control 2015 Dec 1;4:54

Dyar OJ, Pagani L, Pulcini C. Strategies and challenges of antimicrobial stewardship in long-term care facilities. Clin Microbiol Infect 2015 Jan;21(1):10-9

Fleming A, Bradley C, Cullinan S, et al. Antibiotic prescribing in long-term care facilities: a meta-synthesis of qualitative research. Drugs Aging 2015 Apr;32(4):295-303

Holzmann-Pazgal G, Khan AM, Northrup TF, et al. Decreasing vancomycin utilization in a neonatal intensive care unit. Am J Infect Control 2015 Nov 1;43(11):1255-7

Jump RL, Heath B, Crnich CJ, et al. Knowledge, beliefs, and confidence regarding infections and antimicrobial stewardship: a survey of Veterans Affairs providers who care for older adults. Am J Infect Control 2015 Mar 1;43(3):298-300

Kram JJ, Borlaug G, Safdar N, et al. Development and distribution of educational materials for carbapenem-resistant Enterobacteriaceae among acute and long-term care facilities. WMJ 2015 Apr;114(2):48-51

Lim CJ, Stuart RL, Kong DC. Antibiotic use in residential aged care facilities. Aust Fam Physician 2015 Apr;44(4):192-6

Mills JP, Talati NJ, Alby K, et al. The epidemiology of carbapenem-resistant Klebsiella pneumoniae colonization and infection among long-term acute care hospital residents. Infect Control Hosp Epidemiol 2015 (published online Oct 12)

Osowicki J, Gwee A, Noronha J, et al. Australia-wide point prevalence survey of antimicrobial prescribing in neonatal units: how much and how good? Pediatr Infect Dis J 2015 Aug;34(8):e185-90

Pano-Pardo JR, Schuffelmann-Gutierrez C, Escosa-Garcia L, et al. Opportunities to improve antimicrobial use in paediatric intensive care units: a nationwide survey in Spain. Clin Microbiol Infect 2015 (published online Oct 21)

Schulman J, Dimand RJ, Lee HC, et al. Neonatal intensive care unit antibiotic use. Pediatrics 2015 May;135(5):826-33

Shipp KD, Chiang T, Karasick S, et al. Antibiotic stewardship challenges in a referral neonatal intensive care unit. Am J Perinatol 2015 (published online Dec 18)

Stuart RL, Marshall C, Orr E, et al. Survey of infection control and antimicrobial stewardship practices in Australian residential aged-care facilities. Intern Med J 2015 May;45(5):576-80

Tzialla C, Borghesi A, Pozzi M, et al. Neonatal infections due to multi-resistant strains: epidemiology, current treatment, emerging therapeutic approaches and prevention. Clin Chim Acta 2015 Dec 7;451(Pt A):71-7

van Buul LW, van der Steen JT, Achterberg WP, et al. Effect of tailored antibiotic stewardship programmes on the appropriateness of antibiotic prescribing in nursing homes. J Antimicrob Chemother 2015 Jul;70(7):2153-62

van Buul LW, Veenhuizen RB, Achterberg WP, et al. Antibiotic prescribing in Dutch nursing homes: how appropriate is it? J Am Med Dir Assoc 2015 Mar;16(3):229-37

Wu LD, Walker SA, Elligsen M, et al. Antibiotic use and need for antimicrobial stewardship in long-term care. Can J Hosp Pharm 2015 Nov-Dec;68(6):445-9

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2014

Abbo LM, Ariza-Heredia EJ. Antimicrobial stewardship in immunocompromised hosts. Infect Dis Clin North Am 2014 Jun;28(2):263-79

Balkhy HH, Zingg W. Update on infection control challenges in special pediatric populations. Curr Opin Infect Dis 2014 Aug;27(4):370-8

Cantey JB, Patel SJ. Antimicrobial stewardship in the NICU. Infect Dis Clin North Am 2014 Jun;28(2):247-61

Fleet E, Gopal Rao G, Patel B, et al. Impact of implementation of a novel antimicrobial stewardship tool on antibiotic use in nursing homes: a prospective cluster randomized control pilot study. J Antimicrob Chemother 2014 Aug;69(8):2265-73

Hum RS, Cato K, Sheehan B, et al. Developing clinical decision support within a commercial electronic health record system to improve antimicrobial prescribing in the neonatal ICU. Appl Clin Inform 2014 Apr 9;5(2):368-87

Klastersky J, Georgala A. Strategies for the empirical management of infection in cancer patients with emphasis on the emergence of resistant gram-negative bacteria. Crit Rev Oncol Hematol 2014 Dec;92(3):268-78

Lim CJ, Kong DC, Stuart RL. Reducing inappropriate antibiotic prescribing in the residential care setting: current perspectives. Clin Interv Aging 2014 Jan 13;9:165-77

Lim CJ, Kwong MW, Stuart RL, et al. Antibiotic prescribing practice in residential aged care facilities — health care providers' perspectives. Med J Aust 2014 Jul 21;201(2):98-102

Lim CJ, Kwong M, Stuart RL, et al. Antimicrobial stewardship in residential aged care facilities: need and readiness assessment. BMC Infect Dis 2014 Jul 23;14:410

Mazer L, Tapper EB, Piatkowski G, et al. The need for antibiotic stewardship and treatment standardization in the care of cirrhotic patients with spontaneous bacterial peritonitis — a retrospective cohort study examining the effect of ceftriaxone dosing. F1000 Res 2014 Feb 14;3:57

Mikulska M, Del Bono V, Viscoli C. Bacterial infections in hematopoietic stem cell transplantation recipients. Curr Opin Hematol 2014 Nov;21(6):451-8

Mortensen E, Trivedi KK, Rosenberg J, et al. Multidrug-resistant Acinetobacter baumannii infection, colonization, and transmission related to a long-term care facility providing subacute care. Infect Control Hosp Epidemiol 2014 Apr;35(4):406-11

Nace DA, Drinka PJ, Crnich CJ. Clinical uncertainties in the approach to long term care residents with possible urinary tract infection. J Am Med Dir Assoc 2014 Feb;15(2):133-9

Nicolle LE. Antimicrobial stewardship in long term care facilities: what is effective? Antimicrob Resist Infect Control 2014 Feb 12;3(1):6

Nicolle LE. Infection prevention issues in long-term care. Curr Opin Infect Dis 2014 Aug;27(4):363-9

Popoola VO, Budd A, Wittig SM, et al. Methicillin-resistant Staphylococcus aureus transmission and infections in a neonatal intensive care unit despite active surveillance cultures and decolonization: challenges for infection prevention. Infect Control Hosp Epidemiol 2014 Apr;35(4):412-8

Rhee SM, Stone ND. Antimicrobial stewardship in long-term care facilities. Infect Dis Clin North Am 2014 Jun;28(2):237-46

Rosa RG, Goldani LZ, dos Santos RP. Association between adherence to an antimicrobial stewardship program and mortality among hospitalised cancer patients with febrile neutropaenia: a prospective cohort study. BMC Infect Dis 2014 May 23;14:286

Sanders J, Pallotta A, Bauer S, et al. Antimicrobial stewardship program to reduce antiretroviral medication errors in hospitalized patients with human immunodeficiency virus infection. Infect Control Hosp Epidemiol 2014 Mar;35(3):272-7

Satlin MJ, Jenkins SG, Walsh TJ. The global challenge of carbapenem-resistant Enterobacteriaceae in transplant recipients and patients with hematologic malignancies. Clin Infect Dis 2014 May;58(9):1274-83

Shane AL, Stoll BJ. Neonatal sepsis: progress towards improved outcomes. J Infect 2014 Jan;68(Suppl1):S24-32

Venkatachalam I, Yang HL, Fisher D, et al. Multidrug-resistant gram-negative bloodstream infections among residents of long-term care facilities. Infect Control Hosp Epidemiol 2014 May;35(5):519-26

Waters VJ, Ratjen FA. Is there a role for antimicrobial stewardship in cystic fibrosis? Ann Am Thorac Soc 2014 Sep;11(7):1116-9

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2013

Boivin Y, et al. Antibiotic prescription in nursing homes for dependent elderly people: a cross-sectional study in Franche-Comte. Med Mal Infect 2013 Apr;43(4):163-9

Chong Y, et al. Antibiotic rotation for febrile neutropenic patients with haematological malignancies: clinical significance of antibiotic heterogeneity. PLoS One 2013;8:e54190

Cookson B, et al. Development and assessment of national performance indicators for infection prevention and control and antimicrobial stewardship in European long-term care facilities. J Hosp Infect 2013 Sep;85(1):45-53

D'Agata EM, et al. Antimicrobial use and stewardship programs among dialysis centers. Semin Dial 2013 Jul-Aug;26(4):457-64

Daneman N, et al. Prolonged antibiotic treatment in long-term care: role of the prescriber. JAMA Intern Med 2013 Apr 22;173(8):673-82

Donlon S, et al. A national survey of infection control and antimicrobial stewardship structures in Irish long-term care facilities. Am J Infect Control 2013 Jun;41(6):554-7

Gomez DS, et al. Individualised vancomycin doses for paediatric burn patients to achieve PK/PD targets. Burns 2013;39:445-50

Lepainteur M, et al. Prevalence of resistance to antiseptics and mupirocin among invasive coagulase- negative staphylococci from very preterm neonates in NICU: the creeping threat? J Hosp Infect 2013 Apr;83(4):333-6

Moro ML, et al. Antimicrobial resistance and stewardship in long-term care settings. Future Microbiol 2013 Aug;8(8):1011-25

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2012

Chapman AK, et al. Implementation of computerized provider order entry in a neonatal intensive care unit: impact on admission workflow. Int J Med Inform 2012;81:291-5

Jamal JA, et al. Improving antibiotic dosing in special situations in the ICU: burns, renal replacement therapy, and extracorporeal membrane oxygenation. Curr Opin Crit Care 2012;18:460-71

Jump RL, et al. Effective antimicrobial stewardship in a long-term care facility through an infectious disease consultation service: keeping a LID on antibiotic use. Infect Control Hosp Epidemiol 2012 Dec;33(12):1185-92

Patel SJ, Saiman L. Principles and strategies of antimicrobial stewardship in the neonatal intensive care unit. Semin Perinatol 2012;36:431-6

Rolston KV, et al. Antimicrobial de-escalation in cancer patients. Infection 2012 Apr;40(2):223-4

Silva DC, et al. Vancomycin serum concentrations in pediatric oncologic/hematologic intensive care patients. Braz J Infect Dis 2012;16:361-5.

van Buul LW, et al. Antibiotic use and resistance in long term care facilities. J Am Med Dir Assoc 2012 Jul;13(6):568.e1-13

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2011

Chiu CH, et al. Effectiveness of a guideline to reduce vancomycin use in the neonatal intensive care unit. Pediatr Infect Dis J 2011;30:273-8

Van Schooneveld T, et al. Survey of antimicrobial stewardship practices in Nebraska long-term care facilities. Infect Control Hosp Epidemiol 2011 Jul;32(7):732-4

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2010

Milstone AM, et al. Role of decolonization in a comprehensive strategy to reduce methicillin-resistant Staphylococcus aureus infections in the neonatal intensive care unit: an observational cohort study. Infect Control Hosp Epidemiol 2010 May;31(5):558-60

Murki S, et al. Restriction of cephalosporins and control of extended spectrum beta-lactamase producing Gram-negative bacteria in a neonatal intensive care unit. Indian Pediatr 2010;47:785-8

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Infection Control & Stewardship

2016
2015
2014
2013
2012
2011

2016

Buford VR, Kumar V, Kennedy BR. Relationship of various infection control interventions to the prevalence of multidrug-resistant Pseudomonas aeruginosa among US hospitals. Am J Infect Control 2016 Apr 1;44(4):381-6

Cheon S, Kim MJ, Yun SJ, et al. Controlling endemic multidrug-resistant Acinetobacter baumannii in intensive care units using antimicrobial stewardship and infection control. Korean J Intern Med 2016 Mar;31(2):367-74

Dik JW, Poelman R, Friedrich AW, et al. An integrated stewardship model: antimicrobial, infection prevention and diagnostic (AID). Future Microbiol 2016 Jan;11(1):93-102

Frenette C, Sperlea D, Tesolin J, et al. Influence of a 5-year serial infection control and antibiotic stewardship intervention on cardiac surgical site infections. Am J Infect Control 2016 (published online Apr 25)

Giannella M, Tedeschi S, Bartoletti M, et al. Prevention of infections in nursing homes: antibiotic prophylaxis versus infection control and antimicrobial stewardship measures. Expert Rev Anti Infect Ther 2016 Feb;14(2):219-30

Goodman KE, Simner PJ, Tamma PD, et al. Infection control implications of heterogeneous resistance mechanisms in carbapenem-resistant Enterobacteriaceae (CRE). Expert Rev Anti Infect Ther 2016 Nov;14(1):95-108

Kawamura H, Matsumoto K, Shigemi A, et al. A bundle that includes active surveillance, contact precaution for carriers, and cefazolin-based antimicrobial prophylaxis prevents methicillin-resistant Staphylococcus aureus infections in clean orthopedic surgery. Am J Infect Control 2016 Feb;44(2):210-

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2015

Branch-Elliman W, Stanislawski M, Strymish J, et al. Cardiac electrophysiology laboratories: a potential target for antimicrobial stewardship and quality improvement? Open Forum Infect Dis 2015 Fall;2(Suppl 1):133.78

Bryce E, Grant J, Scharf S, et al. Horizontal infection prevention measures and a risk-managed approach to vancomycin-resistant enterococci: an evaluation. Am J Infect Control 2015 Nov 1;43(11):1238-43

Chen CH, Lin LC, Chang YJ, et al. Infection control programs and antibiotic control programs to limit transmission of multi-drug resistant Acinetobacter baumannii Infections: evolution of old problems and new challenges for institutes. Int J Environ Res Public Health 2015 Jul 30;12(8):8871-82

Chen CH, Lin LC, Chang YJ, et al. Long-term effectiveness of infection and antibiotic control programs on the transmission of carbapenem-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii complex in central Taiwan. Med Mal Infect 2015 Jul;45(7):264-72

Gerlich MG, Piegsa J, Schafer C, et al. Improving hospital hygiene to reduce the impact of multidrug-resistant organisms in health care--a prospective controlled multicenter study. BMC Infect Dis 2015 Oct 22;15:441

Goodman KE, Simner PJ, Tamma PD, et al. Infection control implications of heterogeneous resistance mechanisms in carbapenem-resistant Enterobacteriaceae (CRE). Expert Rev Anti Infect Ther 2015 (published online Nov 4)

Murni IK, Duke T, Kinney S, et al. Reducing hospital-acquired infections and improving the rational use of antibiotics in a developing country: an effectiveness study. Arch Dis Child 2015 May;100(5):454-9

Viale P, Giannella M, Bartoletti M, et al. Considerations about antimicrobial stewardship in settings with epidemic extended-spectrum beta-lactamase-producing or carbapenem-resistant Enterobacteriaceae. Infect Dis Ther 2015 Sep;4(Suppl 1):65-83

Whitelaw AC. Role of infection control in combating antibiotic resistance. S Afr Med J 2015 Apr 10;105(5):421

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2014

Chandy SJ, Michael JS, Veeraraghavan B, et al. ICMR programme on antibiotic stewardship, prevention of infection & ontrol (ASPIC). Indian J Med Res 2014 Feb;139(2):226-30

Cheng VC, Tai JW, Chen JH, et al. Proactive infection control measures to prevent nosocomial transmission of vancomycin-resistant enterococci in Hong Kong. J Formos Med Assoc 2014 Oct;113(10):734-41

Di Pentima MC, Chan S, Briody C, et al. Driving forces of vancomycin-resistant E. faecium and E. faecalis blood-stream infections in children. Antimicrob Resist Infect Control 2014 Sep 1;3:29

Gagliotti C, Cappelli V, Carretto E, et al. Control of carbapenemase-producing Klebsiella pneumoniae: a region-wide intervention. Euro Surveill 2014 Oct 30;19:43

Kim NH, Han WD, Song KH, et al. Successful containment of carbapenem-resistant Enterobacteriaceae by strict contact precautions without active surveillance. Am J Infect Control 2014 Dec;42(12):1270-3

Landelle C, Marimuthu K, Harbarth S. Infection control measures to decrease the burden of antimicrobial resistance in the critical care setting. Curr Opin Crit Care 2014 Oct;20(5):499-506

Luna CM, Rodriguez Noriega E, Bavestrello L, et al. Gram-negative infections in adult intensive care units of Latin America and the Caribbean. Crit Care Res Pract 2014;2014:480463

Osman MF, Askari R. Infection control in the intensive care unit. Surg Clin North Am 2014 Dec;94(6):1175-94

Ruhnke M, Arnold R, Gastmeier P. Infection control issues in patients with haematological malignancies in the era of multidrug-resistant bacteria. Lancet Oncol 2014 Dec;15(13):606-19

Savard P, Perl TM. Combating the spread of carbapenemases in Enterobacteriaceae: a battle that infection prevention should not lose. Clin Microbiol Infect 2014 Sep;20(9):854-61

Zoutman DE, Ford BD, Sopha K. Working relationships of infection prevention and control programs and environmental services and associations with antibiotic-resistant organisms in Canadian acute care hospitals. Am J Infect Control 2014 Apr;42(4):349-52

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2013

Donlon S, et al. A national survey of infection control and antimicrobial stewardship structures in Irish long-term care facilities. Am J Infect Control 2013 Jun;41(6):554-7

Kim YC, et al. Trend of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in an institution with a high rate of MRSA after the reinforcement of antibiotic stewardship and hand hygiene. Am J Infect Control 2013 May;41(5):e39-43

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2012

Moehring RW, Anderson DJ. Antimicrobial stewardship as part of the infection prevention effort. Curr Infect Dis Rep 2012;14:592-600

Moody J, et al. Antimicrobial stewardship: a collaborative partnership between infection preventionists and healthcare epidemiologist. Infect Control Hosp Epidemiol 2012 Apr;33(4):322-7

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2011

Dortch MJ, et al. Infection reduction strategies including antibiotic stewardship protocols in surgical and trauma intensive care units are associated with reduced resistant Gram-negative healthcare- associated infections. Surg Infect (Larchmt) 2011;12:15-25

Wilkinson K, et al. Infection prevention and control practices related to Clostridium difficile infection in Canadian acute and long-term care institutions. Am J Infect Control 2011;39:177-82

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Clostridium difficile

2016
2015
2014
2013
2012
2011
2010

2016

Awali RA, Kandipalli D, Pervaiz A, et al. Risk factors associated with interfacility transfers among patients with Clostridium difficile infection. Am J Infect Control 2016 (published online May 17)

Brown KA, Jones M, Daneman N, et al. Importation, antibiotics, and Clostridium difficile infection in veteran long-term care: a multilevel case-control study. Ann Intern Med 2016 Jun 21;164(12):787-94

Brumley PE, Malani AN, Kabara JJ, et al. Effect of an antimicrobial stewardship bundle for patients with Clostridium difficile infection. J Antimicrob Chemother 2016 Mar;71(3):836-40

Chalmers JD, Akram AR, Singanayagam A, et al. Risk factors for Clostridium difficile infection in hospitalized patients with community-acquired pneumonia. J Infect 2016 (published online Apr 19)

Chauv S, Fontaine GV, Hoang QP, et al. Risk of resistant organisms and Clostridium difficile with prolonged systemic antibiotic prophylaxis for central nervous system devices. Neurocrit Care 2016 (published online Feb 26)

Croft L, Ladd J, Doll M, et al. Inappropriate antibiotic use and gastric acid suppression preceding Clostridium difficile infection. (Letter) Infect Control Hosp Epidemiol 2016 Apr;37(4):494-5

Evans ME, Kralovic SM, Simbartl LA, et al. Effect of a Clostridium difficile infection prevention initiative in Veterans Affairs acute care facilities. Infect Control Hosp Epidemiol 2016 Jun;37(6):720-2

Grigoras CA, Zervou FN, Zacharioudakis IM, et al. Isolation of C. difficile carriers alone and as part of a bundle approach for the prevention of Clostridium difficile infection (CDI): a mathematical model based on clinical study data. PLoS One 2016 Jun 3;11(6):e0156577

Hunter JC, Mu Y, Dumyati GK, et al. Burden of nursing home-onset Clostridium difficile infection in the United States: estimates of incidence and patient outcomes. Open Forum Infect Dis 2016 Jan 18;3(1):ofv196

Jasiak NM, Alaniz C, Rao K, et al. Recurrent Clostridium difficile infection in intensive care unit patients. Am J Infect Control 2016 Jan 1;44(1):36-40

Khanafer N, Oltra L, Hulin M, et al. Clostridium difficile infection in a French university hospital: eight years of prospective surveillance study. Medicine (Baltimore) 2016 Jun;95(23):e3874

Kuntz JL, Smith DH, Petrik AF, et al. Predicting the risk of Clostridium difficile infection upon admission: A score to identify patients for antimicrobial stewardship efforts. Perm J 2016 Winter;20(1):20-5

Lytvyn L, Mertz D, Sadeghirad B, et al. Prevention of Clostridium difficile infection: a systematic survey of clinical practice guidelines. Infect Control Hosp Epidemiol 2016 (published online Jun 7)

McKinley L, Becerra B, Moriarty H, et al. Vancomycin-resistant Enterococcus co-colonization rates with methicillin-resistant Staphylococcus aureus and Clostridium difficile in critically ill veterans. Am J Infect Control 2016 (published online Apr 7)

Nanwa N, Kwong JC, Krahn M, et al. The economic burden of hospital acquired Clostridium difficile infection: a population-based matched cohort study. Infect Control Hosp Epidemiol 2016 (published online Jun 20)

Olsen MA, Young-Xu Y, Stwalley D, et al. The burden of Clostridium difficile infection: estimates of the incidence of CDI from US administrative databases. BMC Infect Dis 2016 Apr 22;16:177

Pant C, Deshpande A, Gilroy R, et al. Rising incidence of Clostridium difficile related discharges among hospitalized children in the United States. Infect Control Hosp Epidemiol 2016 Jan;37(1):104-6

Patterson JA, Edmond MB, Hohmann SF, et al. Association between high-risk medication usage and healthcare facility-onset C. difficile infection. Infect Control Hosp Epidemiol 2016 (published online Apr 21)

Radcliff TA, Lorden AL, Zhao H. Clostridium difficile infection in Texas hospitals, 2007-2011. Infect Control Hosp Epidemiol 2016 Mar;37(3):357-9

Reeves JS, Evans ME, Simbartl LA, et al. Clostridium difficile infections in Veterans Health Administration long-term care facilities. Infect Control Hosp Epidemiol 2016 Mar;37(3):295-300

Schwab EM, Wilkes J, Korgenski K, et al. Risk factors for recurrent Clostridium difficile infection in pediatric inpatients. Hosp Pediatr 2016 Jun;6(6):339-44

Shah DN, Aitken SL, Barragan LF, et al. Economic burden of primary compared with recurrent Clostridium difficile infection in hospitalized patients: a prospective cohort study. J Hosp Infect 2016 Jul;93(3):286-9

Sheitoyan-Pesant C, Abou Chakra CN, Pepin J, et al. Clinical and healthcare burden of multiple recurrences of Clostridium difficile infection. Clin Infect Dis 2016 Mar 1;62(5):574-80

Spigaglia P. Recent advances in the understanding of antibiotic resistance in Clostridium difficile infection. Ther Adv Infect Dis 2016 Feb;3(1):23-42

White H, Wiselka M, Bell D. A multi-faceted approach of one teaching hospital NHS trust during the Clostridium difficile epidemic-antibiotic management and beyond. Antibiotics (Basel) 2016 Feb 26;5(1):13

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2015

Abdelsattar ZM, Krapohl G, Alrahmani L, et al. Post-operative burden of hospital-acquired Clostridium difficile infection. Infect Control Hosp Epidemiol 2015 Jan;36(1):40-6

Aguado JM, Anttila VJ, Galperine T, et al. Highlighting clinical needs in Clostridium difficile infection: the views of European healthcare professionals at the front line. J Hosp Infect 2015 Jun;90(2):117-25

Brown K, Valenta K, Fisman D, et al. Hospital ward antibiotic prescribing and the risks of Clostridium difficile infection. JAMA Intern Med 2015 Apr;175(4):626-33

Bouza E, Rodriguez-Creixems M, Alcala L, et al. Is Clostridium difficile infection an increasingly common severe disease in adult intensive care units? A 10-year experience. J Crit Care 2015 Jun;30(3):543-9

Buckel WR, Avdic E, Carroll KC, et al. Gut check: Clostridium difficile testing and treatment in the molecular testing era. Infect Control Hosp Epidemiol 2015 Feb;36(2):217-21

Chopra T, Neelakanta A, Dombecki C, et al. Burden of Clostridium difficile infection on hospital readmissions and its potential impact under the Hospital Readmission Reduction Program. Am J Infect Control 2015 Apr 1;43(4):314-7

Chopra T, Goldstein EJ. Clostridium difficile infection in long-term care facilities: a call to action for antimicrobial stewardship. Clin Infect Dis 2015 May 15;60(Suppl 2):S72-6

Crowther GS, Wilcox MH. Antibiotic therapy and Clostridium difficile infection — primum non nocere — first do no harm. Infect Drug Resist 2015 Sep 15;8:333-7

Daneman N, Guttmann A, Wang X, et al. The association of hospital prevention processes and patient risk factors with the risk of Clostridium difficile infection: a population-based cohort study. BMJ Qual Saf 2015 Jul;24(7):435-43

 Dantes R, Mu Y, Hicks LA, et al. Association between outpatient antibiotic prescribing practices and community-associated Clostridium difficile infection. Open Forum Infect Dis 2015 Aug 11;2(3):ofv113

Evans CT, Safdar N. Current trends in the epidemiology and outcomes of Clostridium difficile infection. Clin Infect Dis 2015 May 15;60(Suppl 2):S66-71

Goldstein EJ, Johnson S, Maziade PJ, et al. Pathway to prevention of nosocomial Clostridium difficile infection. Clin Infect Dis 2015 May 15;60(Suppl 2):S148-58

Hikone M, Ainoda Y, Tago S, et al. Risk factors for recurrent hospital-acquired Clostridium difficile infection in a Japanese university hospital. Clin Exp Gastroenterol 2015 Jul 14;8:191-6

Khanafer N, Voirin N, Barbut F, et al. Hospital management of Clostridium difficile infection: a review of the literature. J Hosp Infect 2015 Jun;90(2):91-101

Knight DR, Giglio S, Huntington PG, et al. Surveillance for antimicrobial resistance in Australian isolates of Clostridium difficile, 2013-14. J Antimicrob Chemother 2015 Nov;70(11):2992-9

Le Saux N, Gravel D, Mulvey M, et al. Healthcare-associated Clostridium difficile infection and strain diversity in pediatric hospitals in the Canadian nosocomial infection surveillance program, 2007-2011. J Pediatric Infect Dis Soc 2015 Dec;4(4):e151-4

Lessa FC, Mu Y, Bamberg WM, et al. Burden of Clostridium infection in the United States. N Engl J Med 2015 Feb 26;372(9):825-34

Llewelyn MJ, Hand K, Hopkins S, et al. Antibiotic policies in acute English NHS trusts: implementation of 'Start Smart-Then Focus' and relationship with Clostridium difficile infection rates. J Antimicrob Chemother 2015 Apr;70(4):1230-5

Magee G, Strauss ME, Thomas SM, et al. Impact of Clostridium difficile-associated diarrhea on acute care length of stay, hospital costs, and readmission: a multicenter retrospective study of inpatients, 2009-2011. Am J Infect Control 2015 Nov 1;43(11):1148-53. doi: 10.1016/j.ajic.2015.06.004

Revolinski S. Implementation of a clinical decision support alert for the management of Clostridium difficile infection. Antibiotics (Basel) 2015 Dec 21;4(4):667-74

Saint S, Fowler KE, Krein SL, et al. Clostridium difficile infection in the United States: a national study assessing preventive practices used and perceptions of practice evidence. Infect Control Hosp Epidemiol 2015 Aug;36(8):969-71

Sarma JB, Marshall B, Cleeve V, et al. Effects of fluoroquinolone restriction (from 2007 to 2012) on Clostridium difficile infections: interrupted time-series analysis. J Hosp Infect 2015 Sep;91(1):74-80

Slayton RB, Scott RD, Baggs J, et al. The cost-benefit of federal investment in preventing Clostridium difficile infections through the use of a multifaceted infection control and antimicrobial stewardship program. Infect Control Hosp Epidemiol 2015 Jun;36(6):681-7

Tartof SY, Rieg GK, Wei R, et al. A comprehensive assessment across the healthcare continuum: risk of hospital-associated Clostridium difficile infection due to outpatient and inpatient antibiotic exposure. Infect Control Hosp Epidemiol 2015 Dec;36(12):1409-16

Van Esch G, Van Broeck J, Delmee M, et al. Surveillance of Clostridium difficile infections in a long-term care psychogeriatric facility: outbreak analysis and policy improvement. Arch Public Health 2015 Apr 6;73(1):18

Wenzler E, Mulugeta SG, Danziger LH. The antimicrobial stewardship approach to combating Clostridium difficile. Antibiotics (Basel) 2015 Jun 17;4(2):198-215

Wong KK, Fraser TG, Shrestha NK, et al. Low incidence of Clostridium difficile infection (CDI) in patients treated with outpatient parenteral antimicrobial therapy (OPAT). Infect Control Hosp Epidemiol 2015 Jan;36(1):110-2

Yeung SS, Yeung JK, Lau TT, et al. Evaluation of a Clostridium difficile infection management policy with clinical pharmacy and medical microbiology involvement at a major Canadian teaching hospital. J Clin Pharm Ther 2015 Dec;40(6):655-60

Young-Xu Y, Kuntz JL, Gerding DN, et al. Clostridium difficile infection among Veterans Health Administration patients. Infect Control Hosp Epidemiol 2015 Sep;36(9):1038-45

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2014

Allen UD, Canadian Paediatric Society, Infectious Diseases and Immunization Committee. Clostridium difficile in paediatric populations. Paediatr Child Health 2014 Jan;19(1):43-54

Banach DB, Francois J, Blash S, et al. Active surveillance for carbapenem-resistant Enterobacteriaceae using stool specimens submitted for testing for Clostridium difficile. Infect Control Hosp Epidemiol 2014 Jan;35(1):82-4

Beran V, Chmelar D, Vobejdova J, et al. Sensitivity to antibiotics of Clostridium difficile toxigenic nosocomial strains. Folia Microbiol (Praha) 2014 May;59(3):209-15

Brown KA, Fisman DN, Moineddin R, et al. The magnitude and duration of Clostridium difficile infection risk associated with antibiotic therapy: a hospital cohort study. PLoS One 2014 Aug 26;9(8):e105454

Buchler AC, Rampini SK, Stelling S, et al. Antibiotic susceptibility of Clostridium difficile is similar worldwide over two decades despite widespread use of broad-spectrum antibiotics: an analysis done at the University Hospital of Zurich. BMC Infect Dis 2014 Nov 26;14:607

Chahine EB, Sucher AJ, Mantei K. Fidaxomicin: a novel macrolide antibiotic for Clostridium difficile infection. Consult Pharm 2014 Sep;29(9):614-24

Chilton CH, Crowther GS, Freeman J, et al. Successful treatment of simulated Clostridium difficile infection in a human gut model by fidaxomicin first line and after vancomycin or metronidazole failure. J Antimicrob Chemother 2014 Feb;69(2):451-62

Chung P, Currie B, Guo Y, et al. Investigation to identify a resource-efficient case-control methodology for determining antibiotics associated with Clostridium difficile infection. Am J Infect Control 2014 Oct;42(10 Suppl):S264-8

Cornely OA, Nathwani D, Ivanescu C, et al. Clinical efficacy of fidaxomicin compared with vancomycin and metronidazole in Clostridium difficile infections: a meta-analysis and indirect treatment comparison. J Antimicrob Chemother 2014 Nov;69(11):2892-900

Cruz-Rodriguez NC, Hernandez-Garcia R, Salinas-Caballero AG, et al. The effect of pharmacy restriction of clindamycin on Clostridium difficile infection rates in an orthopedics ward. Am J Infect Control 2014 Jun;42(6):e71-3

D'Agostino RB Sr, Collins SH, Pencina KM, et al. Risk estimation for recurrent Clostridium difficile infection based on clinical factors. Clin Infect Dis 2014 May;58(10:1386-93

Doh YS, Kim YS, Jung HJ, et al. Long-term clinical outcome of Clostridium difficile infection in hospitalized patients: a single center study. Intest Res 2014 Oct;12(4):299-305

Dubberke ER, Schaefer E, Reske KA, et al. Attributable inpatient costs of recurrent Clostridium difficile infections. Infect Control Hosp Epidemiol 2014 Nov;35(11):1400-8

DuPont HL. Challenges and opportunities in the management of Clostridium difficile infection. Expert Rev Gastroenterol Hepatol 2014 Nov;8(8):863-74

Esmaily-Fard A, Tverdek FP, Crowther DM, et al. The use of fidaxomicin for treatment of relapsed Clostridium difficile infections in patients with cancer. Pharmacotherapy 2014 Nov;34(11):1220-5

Feazel LM, Malhotra A, Perencevich EN, et al. Effect of antibiotic stewardship programmes on Clostridium difficile incidence: a systematic review and meta-analysis. J Antimicrob Chemother 2014 Jul;69(7):1748-54

Ferreyra JA, Wu KJ, Hryckowian AJ, et al. Gut microbiota-produced succinate promotes C. difficile infection after antibiotic treatment or motility disturbance. Cell Host Microb 2014 Dec 10;16(6):770-7

Fisher BT, Sammons JS, Li Y, et al. Variation in risk of hospital-onset Clostridium difficile infection across beta-lactam antibiotics in children with new-onset acute lymphoblastic leukemia. J Pediatric Infect Dis Soc 2014 Dec;3(4):329-35

Garneau JR, Valiquette L, Fortier LC. Prevention of Clostridium difficile spore formation by sub-inhibitory concentrations of tigecycline and piperacillin/tazobactam. BMC Infet Dis 2014 Jan 15;14:29

Haran JP, Hayward G, Skinner S, et al. Factors influencing the development of antibiotic associated diarrhea in ED patients discharged home: risk of administering IV antibiotics. Am J Emerg Med 2014 Oct;32(10):1195-9

Honda H, Dubberke ER. The changing epidemiology of Clostridium difficile infection. Curr Opin Gastroenterol 2014 Jan;30(1):54-62

Johnson S, Louie T, Gerding DN, et al. Vancomycin, metronidazole, or tolevamer for Clostridium difficile infection: results from two multinational, randomized, controlled trials. Clin Infect Dis 2014 Aug 1;59(3):345-54

Kamboj M, Babady NE, Marsh JW, et al. Estimating risk of C. difficile transmission from PCR positive but cytotoxin negative cases. PLoS One 2014 Feb 11;9(2):e88262

Keshavamurthy S, Koch CG, Fraser TG, et al. Clostridium difficile infection after cardiac surgery: prevalence, morbidity, mortality, and resource utilization. J Thorac Cardiovasc Surg 2014 Dec;148(6):3157-65

Knecht H, Neulinger SC, Heinsen FA, et al. Effects of beta-lactam antibiotics and fluoroquinolones on human gut microbiota in relation to Clostridium difficile associated diarrhea. PLoS One 2014 Feb 28;9(2):e89417

Lee JH, Lee Y, Lee K, et al. The changes of PCR ribotype and antimicrobial resistance of Clostridium difficile in a tertiary care hospital over 10 years. J Med Microbiol 2014 Jun;63(Pt 6):819-23

Locher HH, Caspers P, Bruyere T, et al. Investigations of the mode of action and resistance development of cadazolid, a new antibiotic for treatment of Clostridium difficile infections. Antimicrob Agents Chemother 2014;58(2):901-8

Luciano JA, Zuckerbraun BS. Clostridium difficile infection: prevention, treatment, and surgical management. Surg Clin North Am 2014 Dec;94(6):1335-49

Macy E, Contreras R. Health care use and serious infection prevalence associated with penicillin "allergy" in hospitalized patients: a cohort study. J Allergy Clin Immunol 2014 Mar;133(3):790-6

Matsumoto K, Kanazawa N, Shigemi A, et al. Factors affecting treatment and recurrence of Clostridium difficile infections. Biol Pharm Bull 2014;37(11):1811-5

Mathur H, Rea MC, Cotter PD, et al. The potential for emerging therapeutic options for Clostridium difficile infection. Gut Microbes 2014;5(6):696-710

Mullane K. Fidaxomicin in Clostridium difficile infection: latest evidence and clinical guidance. Ther Adv Chronic Dis 2014 Mar;5(2):69-84

Na JY, Park JM, Lee KS, et al. Clinical characteristics of symptomatic Clostridium difficile infection in children: conditions as infection risks and whether probiotics is effective. Pediatr Gastroenterol Hepatol Nutr 2014 Dec;17(4):232-8

Nathwani D, Cornely OA, Van Engen AK, et al. Cost-effectiveness analysis of fidaxomicin versus vancomycin in Clostridium difficile infection. J Antimicrob Chemother 2014 Nov;69(11):2901-12

O'Horo JC, Jindai K, Kunzer B, et al. Treatment of recurrent Clostridium difficile infection: a systematic review. Infection 2014 Feb;42(1):43-59

Oleastro M, Coelho M, Giao M, et al. Outbreak of Clostridium difficile PCR ribotype 027 — the recent experience of a regional hospital. BMC Infect Dis 2014 Apr 17;14:209

Ostrowsky B, Ruiz R, Brown S, et al. Lessons learned from implementing Clostridium difficile-focused antibiotic stewardship interventions. Infect Control Hosp Epidemiol 2014 Oct;35(Suppl 3):S86-95

Pakyz AL, Jawahar R, Wang Q, et al. Medication risk factors associated with healthcare-associated Clostridium difficile infection: a multilevel model case-control study among 64 US academic medical centres. J Antimicrob Chemother 2014 Apr;69(4):1127-31

Parmar SR, Bhatt V, Yang J, et al. A retrospective review of metronidazole and vancomycin in the management of Clostridium difficile infection in patients with hematologic malignancies. J Oncol Pharm Pract 2014 Jun;20(3):172-82

Rodriguez S, Hernandez MB, Tarchini G, et al. Risk of Clostridium difficile infection in hospitalized patients receiving metronidazole for a non-C difficile infection. Clin Gastroenterol Hepatol 2014 Nov;12(11):1856-61

Samady W, Bush R, Pong A, et al. Predictors of Clostridium difficile infections in hospitalized children. J Hosp Med 2014 Feb;9(2):94-8

Samady W, Pong A, Fisher E. Risk factors for the development of Clostridium difficile infection in hospitalized children. Curr Opin Pediatr 2014 Oct;26(5):568-72

Shivashankar R, Khanna S, Kammer PP, et al. Clinical predictors of recurrent Clostridium difficile infection in out-patients. Aliment Pharmacol Ther 2014 Sep;40(5):518-22

Slimings C, Riley TV. Antibiotics and hospital-acquired Clostridium difficile infection: update of systematic review and meta-analysis. J Antimicrob Chemother 2014 Apr;69(4):881-91

Smith LA, Chan CK, Halm M, et al. Development and validation of a Clostridium difficile risk assessment tool. AACN Adv Crit Care 2014 Oct-Dec;25(4):334-46

Taori SK, Wroe A, Hardie A, et al. A prospective study of community-associated Clostridium difficile infections: the role of antibiotics and co-infections. J Infect 2014 Aug;69(2):134-44

Thomas A, Khan F, Uddin N, et al. Tigecycline for severe Clostridium difficile infection. Int J Infect Dis 2014 Sep;26:171-2

Tickler IA, Goering RV, Whitmore JD, et al. Strain types and antimicrobial resistance patterns of Clostridium difficile isolates from the United States, 2011 to 2013. Antimicrob Agents Chemother 2014 Jul;58(7):4214-8

Tschudin-Sutter S, Tamma PD, Milstone AM, et al. The prediction of complicated Clostridium difficile infections in children. Infect Control Hosp Epidemiol 2014 Jul;35(7):901-3

Tschudin-Sutter S, Tamma PD, Milstone AM, et al. Predictors of first recurrence of Clostridium difficile infections in children. Pediatr Infect Dis J 2014 Apr;33(4):414-6

Turner RB, Smith CB, Martello JL, et al. Role of doxycycline in Clostridium difficile infection acquisition. Ann Pharmacother 2014 Jun;48(6):772-6

Vargo CA, Bauer KA, Mangino JE, et al. An antimicrobial stewardship program's real-world experience with fidaxomicin for treatment of Clostridium difficile infection: a case series. Pharmacotherapy 2014 Sep;34(9):901-9

Varier RU, Biltaji E, Smith KJ, et al. Cost-effectiveness analysis of treatment strategies for initial Clostridium difficile infection. Clin Microbiol Infect 2014 Dec;20(12):1343-51

Vassallo A, Tran MC, Goldstein EJ. Clostridium difficile: improving the prevention paradigm in healthcare settings. Expert Rev Anti Infect Ther 2014 Sep;12(9):1087-102

Vehreschild MJ, Weitershagen D, Biehl LM, et al. Clostridium difficile infection in patients with acute myelogenous leukemia and in patients undergoing allogeneic stem cell transplantation: epidemiology and risk factor analysis. Biol Blood Marrow Transplant 2014 Jun;20(6)823-8

Walters PR, Zuckerbraun BS. Clostridium difficile infection: clinical challenges and management strategies. Crit Care Nurse 2014 Aug;34(4):24-34

Wendt JM, Cohen JA, Mu Y, et al. Clostridium difficile infection among children across diverse US geographic locations. Pediatrics 2014 Apr;133(4):651-8

Wenisch JM, Equiluz Bruck S, Fudel M, et al. Decreasing Clostridium difficile infections by an antimicrobial stewardship program that reduces moxifloxacin use. Antimicrob Agents Chemother 2014 Sep;58(9):5079-83

Yakob L, Riley TV, Paterson DL, et al. Assessing control bundles for Clostridium difficile: a review and mathematical model. Emerg Microbes Infect 2014 Jun;3(6):e43

Zilberberg MD, Reske K, Olsen M, et al. Development and validation of a recurrent Clostridium difficile risk-prediction model. J Hosp Med 2014 Jul;9(7):418-23

Zilberberg MD, Reske K, Olsen M, et al. Risk factors for recurrent Clostridium difficile infection (CDI) hospitalization among hospitalized patients with an initial CDI episode: a retrospective cohort study. BMC Infect Dis 2014 Jun 4;14:306

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2013

Brakovich B, et al. War on the spore: Clostridium difficile disease among patients in a long-term acute care hospital. J Healthc Qual 2013 May-Jun;35(3):15-21

Haines CF, et al. Clostridium difficile in a HIV-infected cohort: incidence, risk factors, and clinical outcomes. AIDS 2013 Nov 13;27(17):2799-807

Jardin CG, et al. Assessment of treatment patterns and patient outcomes before vs after implementation of a severity-based Clostridium difficile infection treatment policy. J Hosp Infect 2013 Sep;85(1):28-32

Jury LA, et al. A Clostridium difficile infection (CDI) stewardship initiative improves adherence to practice guidelines for management of CDI. Infect Control Hosp Epidemiol 2013 Nov;34(11):1222-4

Montoya M, et al. Antimicrobial selection and its impact on the incidence of Clostridium difficile- associated diarrhea. J Pharm Pract 2013 Oct;26(5):483-7

Piacenti FJ, et al. Antimicrobial stewardship and Clostridium difficile-associated diarrhea. J Pharm Pract 2013 Oct;26(5):506-13

Srigley JA, et al. Inappropriate use of antibiotics and Clostridium difficile infection. Am J Infect Control 2013 Nov;41(11):1116-8

Stanley JD, et al. Clostridium difficile infection. Curr Probl Surg 2013 Jul;50(7):302-37

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2012

Aldeyab MA, et al. An evaluation of the impact of antibiotic stewardship on reducing the use of high- risk antibiotics and its effect on the incidence of Clostridium difficile infection in hospital settings. J Antimicrob Chemother 2012;67:2988-96

CDC. Preventing Clostridium difficile infections. (Vital signs) MMWR 2012 Mar 9;61:157-62

Tschudin-Sutter S et al. Clostridium difficile: novel insights on an incessantly challenging disease. Curr Opin Infect Dis 2012 Aug;25(4):405-11

Wiegand PN, et al. Clinical and economic burden of Clostridium difficile infection in Europe: a systematic review of healthcare-facility-acquired infection. J Hosp Infect 2012 May;81(1):1-14

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2011

Aldeyab MA, et al. Multihospital outbreak of Clostridium difficile ribotype 027 infection: epidemiology and analysis of control measures. Infect Control Hosp Epidemiol 2011;32:210-9

Polgreen PM, et al. Using oral vancomycin prescriptions as a proxy measure for Clostridium difficile infections: a spatial and time series analysis. Infect Control Hosp Epidemiol 2011 Jul;32(7):723-6

Wilkinson K, et al. Infection prevention and control practices related to Clostridium difficile infection in Canadian acute and long-term care institutions. Am J Infect Control 2011;39:177-82

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2010

Bartlett JG. Clostridium difficile: progress and challenges. Ann N Y Acad Sci 2010 Dec;1213:62-9

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Veterinary, Ag, Environment

2016
2015
2014

2016

Aitken SL, Dilworth TJ, Heil EL, et al. Agricultural applications for antimicrobials. A danger to human health: an official position statement of the society of infectious diseases pharmacists. Pharmacotherapy 2016 Apr;36(4):422-32

Bean TG, Bergstrom E, Thomas-Oates J, et al. Evaluation of a novel approach for reducing emissions of pharmaceuticals to the environment. Environ Manage 2016 (published online Jun 24)

Elmahdi S, DaSilva LV, Parveen S. Antibiotic resistance of Vibrio parahaemolyticus and Vibrio vulnificus in various countries: a review. Food Microbiol 2016 Aug;57:128-34

Guo Y, Zhou H, Qin L, et al. Frequency, antimicrobial resistance and genetic diversity of Klebsiella pneumoniae in food samples. PLoS One 2016 Apr 14;11(4):e0153561

Lammie SL, Hughes JM. Antimicrobial resistance, food safety, and one health: the need for convergence. Annu Rev Food Sci Technol 2016;7:287-312

Ojo OE, Fabusoro E, Majasan AA, et al. Antimicrobials in animal production: usage and practices among livestock farmers in Oyo and Kaduna States of Nigeria. Trop Anim Health Prod 2016 Jan;48(1):189-97

Toombs-Ruane LJ, Riley CB, Kendall AT, et al. Antimicrobial susceptibility of bacteria isolated from neonatal foal samples submitted to a New Zealand veterinary pathology laboratory (2004 to 2013). N Z Vet J 2016 Mar;64(2):107-11

Wang S, Zeng X, Yang Q, et al. Antimicrobial peptides as potential alternatives to antibiotics in food animal industry. Int J Mol Sci 2016 May 3;17(5):603

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2015

Aarestrup FM. The livestock reservoir for antimicrobial resistance: a personal view on changing patterns of risks, effects of interventions and the way forward. Philos Trans R Soc Lond B Biol Sci 2015 Jun 5;370(1670):20140085

Abdalrahman LS, Stanley A, Wells H, et al. Isolation, virulence, and antimicrobial resistance of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) strains from Oklahoma retail poultry meats. Int J Environ Res Public Health 2015 May 29;12(6):6148-61

Agga GE, Arthur TM, Durso LM, et al. Antimicrobial-resistant bacterial populations and antimicrobial resistance genes obtained from environments impacted by livestock and municipal waste. PLoS One 2015 Jul 21;10(7):e0132586

Argudin MA, Vanderhaeghen W, Vandendriessche S, et al. Antimicrobial resistance and population structure of Staphylococcus epidermidis recovered from animals and humans. Vet Microbiol 2015 Jul 9;178(1-2):105-13

Berendonk TU, Manaia CM, Merlin C, et al. Tackling antibiotic resistance: the environmental framework. Nat Rev Microbiol 2015 May;13(5):310-7

Bjork KE, Kopral CA, Wagner BA, et al. Comparison of mixed effects models of antimicrobial resistance metrics of livestock and poultry Salmonella isolates from a national monitoring system. Prev Vet Med 2015 Dec 1;122(3):265-72

Catry B, Cavaleri M, Baptiste K, et al. Use of colistin-containing products within the European Union and European Economic Area (EU/EEA): development of resistance in animals and possible impact on human and animal health. Int J Antimicrob Agents 2015 Sep;46(3):297-306

Dahshan H, Abd-Elall AM, Megahed AM, et al. Veterinary antibiotic resistance, residues, and ecological risks in environmental samples obtained from poultry farms, Egypt. Environ Monit Assess 2015 Feb;187:2

Donado-Godoy P, Byrne BA, Leon M, et al. Prevalence, resistance patterns, and risk factors for antimicrobial resistance in bacteria from retail chicken meat in Colombia. J Food Prot 2015 Apr;78(4):751-9

Donado-Godoy P, Castellanos R, Leon M, et al. The establishment of the Colombian integrated program for antimicrobial resistance surveillance (COIPARS): a pilot project on poultry farms, slaughterhouses and retail market. Zoonoses Public Health 2015 Apr;62(Suppl 1):58-69

Doyle ME. Multidrug-resistant pathogens in the food supply. Foodborne Pathog Dis 2015 Apr;12(4):261-79

Economou V, Gousia P. Agriculture and food animals as a source of antimicrobial-resistant bacteria. Infect Drug Resist 2015 Apr 1;8:49-61

Fletcher S. Understanding the contribution of environmental factors in the spread of antimicrobial resistance. Environ Health Prev Med 2015 Jul;20(4):243-52

Guardabassi L, Prescott JF. Antimicrobial stewardship in small animal veterinary practice: from theory to practice. Vet Clin North Am Small Anim Pract 2015 Mar;45(2):361

Hanon JB, Jaspers S, Butaye P, et al. A trend analysis of antimicrobial resistance in commensal Escherichia coli from several livestock species in Belgium (2011-2014). Prev Vet Med 2015 Dec 1;122(4):443-52

Hiki M, Kawanishi M, Abo H, et al. Decreased resistance to broad-spectrum cephalosporin in Escherichia coli from healthy broilers at farms in Japan after voluntary withdrawal of ceftiofur. Foodborne Pathog Dis 2015 Jul;12(7):639-43

Huijbers PM, Blaak H, de Jong MC, et al. Role of the environment in the transmission of antimicrobial resistance to humans: a review. Environ Sci Technol 2015 Oct 20;49(20):11993-2004

Jones PJ, Marier EA, Tranter RB, et al. Factors affecting dairy farmers' attitudes towards antimicrobial medicine usage in cattle in England and Wales. Prev Vet Med 2015 Sep 1;121(1-2):30-40

Leger DF, Newby NC, Reid-Smith R, et al. Antimicrobial dispensing by Ontario dairy veterinarians. Can Vet J 2015 Jul;56(7):723-9

McCrackin MA, Helke KL, Galloway AM, et al. Effect of antimicrobial use in agricultural animals on drug-resistant foodborne campylobacteriosis in humans: a systematic literature review. Crit Rev Food Sci Nutr 2015 (published online Nov 18)

McIntosh W, Dean W. Factors associated with the inappropriate use of antimicrobials. Zoonoses Public Health 2015 Apr;62(Suppl 1):22-8

Meek RW, Vyas H, Piddock LJ. Nonmedical uses of antibiotics: time to restrict their use? PLoS Biol 2015 Oct 7;13(10):e1002266

Menz J, Schneider M, Kummerer K. Usage pattern-based exposure screening as a simple tool for the regional priority-setting in environmental risk assessment of veterinary antibiotics: a case study of north-western Germany. Chemosphere 2015 May;127:42-8

Ojo OE, Fabusoro E, Majasan AA, et al. Antimicrobials in animal production: usage and practices among livestock farmers in Oyo and Kaduna States of Nigeria. Trop Anim Health Prod 2015 (published online Nov 2)

Paulson JA, Zaoutis TE, Council on Environmental Health, et al. Nontherapeutic use of antimicrobial agents in animal agriculture: implications for pediatrics. Pediatrics 2015 Dec;136(6):e1670-7

Rushton J. Antimicrobial use in animals: how to assess the trade-offs. Zoonoses Public Health 2015 Apr;62(Suppl 1):10-21

Sahin O, Kassem II, Shen Z, et al. Campylobacter in poultry: ecology and potential interventions. Avian Dis 2015 Jun;59(2):185-200

Scott HM, Midgley G, Loneragan GH. Antimicrobials in animal agriculture: parables and policy. Zoonoses Public Health 2015 Apr;62(Suppl 1):3-9

Speksnijder DC, Jaarsma AD, van der Gugten AC, et al. Determinants associated with veterinary antimicrobial prescribing in farm animals in the Netherlands: a qualitative study. Zoonoses Public Health 2015 Apr;62(Suppl 1):39-51

Speksnijder DC, Jaarsma DA, Verheij TJ, et al. Attitudes and perceptions of Dutch veterinarians on their role in the reduction of antimicrobial use in farm animals. Prev Vet Med 2015 Oct 1;121(3-4):365-73

Speksnijder DC, Mevius DJ, Bruschke CJ, et al. Reduction of veterinary antimicrobial use in the Netherlands. The Dutch success model. Zoonoses Public Health 2015 Apr;62(Suppl 1):79-87

Tellez G, Laukova A, Latorre JD, et al. Food-producing animals and their health in relation to human health. Microb Ecol Health Dis 2015 Feb 2;26:25876

Van Boeckel TP, Brower C, Gilbert M, et al. Global trends in antimicrobial use in food animals. Proc Natl Acad Sci U S A 2015 May 5;112(18):5649-54

Visschers VH, Backhans A, Collineau L, et al. Perceptions of antimicrobial usage, antimicrobial resistance and policy measures to reduce antimicrobial usage in convenient samples of Belgian, French, German, Swedish and Swiss pig farmers. Prev Vet Med 2015 Apr 1;119(1-2):10-20

Weese JS, Giguere S, Guardabassi L, et al. ACVIM consensus statement on therapeutic antimicrobial use in animals and antimicrobial resistance. J Vet Intern Med 2015 Mar-Apr;29(2):487-98

Woolhouse M, Ward M, van Bunnik B, et al. Antimicrobial resistance in humans, livestock and the wider environment. Philos Trans R Soc Lond B Biol Sci 2015 Jun 5;370(1670):20140083

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2014

Bengtsson B, Greko C. Antibiotic resistance--consequences for animal health, welfare, and food production. Ups J Med Sci 2014 May;119(2):96-102

Forslund K, Sunagawa S, Coelho LP, et al. Metagenomic insights into the human gut resistome and the forces that shape it. Bioessays 2014 Mar;36(3):316-29

Perry JA, Wright GD. Forces shaping the antibiotic resistome. Bioessays 2014 Dec;36(12):1179-84

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Developing Antibiotics

2016
2015
2014
2013
2012
2011
2010

2016

Anderson T. Countries mull over incentives for developing antibiotics. Lancet 2016 May 7;387(10031):1894-5

Andersson JA, Fitts EC, Kirtley ML, et al. New role for FDA-approved drugs in combating antibiotic-resistant bacteria. Antimicrob Agents Chemother 2016 May 23;60(6):3717-29

Fortman JL, Mukhopadhyay A. The future of antibiotics: emerging technologies and stewardship. Trends Microbiol 2016 Jul;24(7):515-7

Outterson K, Gopinathan U, Clift C, et al. Delinking investment in antibiotic research and development from sales revenues: the challenges of transforming a promising idea into reality. PLoS Med 2016 Jun 14;13(6):e1002043

Outterson K, McDonnell A. Funding antibiotic innovation with vouchers: recommendations on how to strengthen a flawed incentive policy. Health Aff (Millwood) 2016 May 1;35(5):784-90

Renwick MJ, Brogan DM, Mossialos E. A systematic review and critical assessment of incentive strategies for discovery and development of novel antibiotics. J Antibiot (Tokyo) 2016 Feb;69(2):73-88

Rex JH, Outterson K. Antibiotic reimbursement in a model delinked from sales: a benchmark-based worldwide approach. Lancet Infect Dis 2016 Apr;16(4):500-5

Wenzler E, Wong JR, Goff DA, et al. Controversies in antimicrobial stewardship: focus on new rapid diagnostic technologies and antimicrobials. Antibiotics (Basel) 2016 Jan 14;5(1):6

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2015

Amin AN, Deruelle D. Healthcare-associated infections, infection control and the potential of new antibiotics in development in the USA. Future Microbiol 2015;10(6):1049-62

Bassetti M, Righi E. Development of novel antibacterial drugs to combat multiple resistant organisms. Langenbecks Arch Surg 2015 Feb;400(2):153-65

Bax R, Green S. Antibiotics: the changing regulatory and pharmaceutical industry paradigm. J Antimicrob Chemother 2015 May;70(5):1281-4

Bettiol E, Harbarth S. Development of new antibiotics: taking off finally? Swiss Med Wkly 2015 Jul 31;145:w14167

Brandenburg K, Schurholz T. Lack of new antiinfective agents: passing into the pre-antibiotic age? World J Biol Chem 2015 Aug 26;6(3):71-7

Draenert R, Seybold U, Grutzner E, et al. Novel antibiotics: are we still in the pre-post-antibiotic era? Infection 2015 Apr;43(2):145-51

Eichberg MJ. Public funding of clinical-stage antibiotic development in the United States and European Union. Health Secur 2015 May-Jun;13(3):156-65

Harbarth S, Theuretzbacher U, Hackett J, et al. Antibiotic research and development: business as usual? J Antimicrob Chemother 2015;70(6):1604-7

Kandi V, Kandi S. Antimicrobial properties of nanomolecules: potential candidates as antibiotics in the era of multi-drug resistance. Epidemiol Health 2015 Apr 17;37:e2015020

Kostyanev T, Bonten MJ, O'Brien S, et al. The Innovative Medicines Initiative's New Drugs for Bad Bugs programme: European public-private partnerships for the development of new strategies to tackle antibiotic resistance. J Antimicrob Chemother 2015 (published online Nov 15)

O'Brien S. Meeting the societal need for new antibiotics: the challenges for the pharmaceutical industry. Br J Clin Pharmacol 2015 Feb;79(2):168-72

Outterson K, Powers JH, Daniel GW, et al. Repairing the broken market for antibiotic innovation. Health Aff (Millwood) 2015 Feb;34(2):277-85

Payne DJ, Miller LF, Findlay D, et al. Time for a change: addressing R&D and commercialization challenges for antibacterials. Philos Trans R Soc Lond B Biol Sci 2015 Jun 5;370(1670):20140086

Renwick MJ, Brogan DM, Mossialos E. A systematic review and critical assessment of incentive strategies for discovery and development of novel antibiotics. J Antibiot (Tokyo) 2015 (published online Oct 14)

Spellberg B, Bartlett J, Wunderink R, et al. Novel approaches are needed to develop tomorrow's antibacterial therapies. Am J Respir Crit Care Med 2015 Jan 15;191(2):135-40

Thabit AK, Crandon JL, Nicolau DP. Antimicrobial resistance: impact on clinical and economic outcomes and the need for new antimicrobials. Expert Opin Pharmacother 2015 Feb;16(2):159-77

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2014

Brooks BD, Brooks AE. Therapeutic strategies to combat antibiotic resistance. Adv Drug Deliv Rev 2014 Nov 30;78:14-27

Dryden MS. Novel antibiotic treatment for skin and soft tissue infection. Curr Opin Infect Dis 2014 Apr;27(2):116-24

Lin L, Pantapalangkoor P, Tan B, et al. Transferrin iron starvation therapy for lethal bacterial and fungal infections. J Infect Dis 2014 Jul 15;210(2):254-64

Spellberg B. The future of antibiotics. Crit Care 2014 Jun 27;18(3):228

Spellberg B, Shlaes D. Prioritized current unmet needs for antibacterial therapies. Clin Pharmacol Ther 2014 Aug;96(2):151-3

Srinivasan A, Lopez Ribot JL, Ramasubramanian AK. Overcoming antifungal resistance. Drug Discov Today Technol 2014 Mar;11:65-71

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2013

Boucher HW, et al. 10 x '20 progress--development of new drugs active against gram-negative bacilli: an update from the Infectious Diseases Society of America. Clin Infect Dis 2013;56:1685-94

Pujol M, et al. Evaluation of new antimicrobials for the hospital formulary: policies restricting antibiotic use in hospitals. Enferm Infecc Microbiol Clin 2013 Sep;31(Suppl 4):45-50

Rex JH, et al. A comprehensive regulatory framework to address the unmet need for new antibacterial treatments. Lancet Infect Dis 2013;13:269-75

Schlaes DM, et al. The FDA reboot of antibiotic development. Antimicrob Agents Chemother 2013 Oct;57(10):4605-7

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2012

Shlaes DM, et al. Overcoming the challenges to developing new antibiotics. Curr Opin Pharmacol 2012 Oct;12(5):522-6

Spellberg B, et al. The critical impact of time discounting on economic incentives to overcome the antibiotic market failure. Nat Rev Drug Discov 2012 Feb 1; 11(2):168

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2011

Laxminarayan R, et al. Antibacterial R&D incentives. Nat Rev Drug Discov 2011 Sep30;10(10):727-8

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2010

IDSA. The 10 x ’20 Initiative: pursuing a global commitment to develop 10 new antibacterial drugs by 2020. Clin Infect Dis 2010 Apr 15;50(8):1081-3

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Recent News

Aug 24, 2016
Baby with thermometer

Genetic tests could speed infection diagnosis in infants

Two studies show the potential of genetics to quickly tell bacterial from viral infections in feverish infants.

Aug 22, 2016

News Scan for Aug 22, 2016

New chikungunya cases
Ohio Crypto outbreak
Resistant E coli in drinking water
African Salmonella
Aug 19, 2016
Antibiotics prescription

Experts propose global targets for cutting antibiotic use

Global health experts urge the UN to set worldwide targets for reduced antibiotic consumption.

Aug 19, 2016

ASP News Scan for Aug 19, 2016

MCR-1 in UTI in Switzerland
Burden of bloodstream infections
MRSA and fatal flu infections
Aug 19, 2016

News Scan for Aug 19, 2016

MCR-1 in UTI in Switzerland
HPV vaccine acceptance
UN cholera lawsuit immunity
Aug 18, 2016

News Scan for Aug 18, 2016

Saudi MERS case
Burden of bloodstream infections
UN Haiti cholera shift
Contact lens infections
Aug 15, 2016

Flu Scan for Aug 15, 2016

More H3N2v in Michigan pigs
MRSA and fatal flu infections
Aug 12, 2016

ASP News Scan for Aug 12, 2016

MRSA in people and pigs
New TB guidelines
HIV and drug-resistant TB
Aug 12, 2016

News Scan for Aug 12, 2016

Yellow fever in Angola, DRC
Childhood vaccine costs
MRSA in people and pigs
Aug 11, 2016
Drug-resistant Shigella

Drug-resistant Shigella on the rise in gay men

Two reports today detail evidence of rising antibiotic-resistant Shigella among men who have sex with men.

Online Resources

Resources


US Health, Policy, and Government Initiatives

  • Get Smart for Healthcare (Centers for Disease Control and Prevention) - A national initiative provides evidence to support stewardship (eg, resistance and healthcare-associated infection rates, healthcare costs), inpatient implementation core elements, guidance for stewardship in long-term care, program examples, and educational resources.
  • Antibiotic Stewardship in Acute Care: A Practical Playbook  (Centers for Disease Control and Prevention, the National Quality Forum, and the Hospital Corporation of America) - The playbook offers practical strategies for building or enhancing an antibiotic stewardship program in acute care hospitals.
  • Antibiotic Resistance Project (The Pew Charitable Trusts) - The ARP supports policies that would spur the creation of new antibiotics, establish stewardship programs to ensure that antibiotics are prescribed only when necessary in human health care settings, and end the overuse of antibiotics in food animals.


International Initiatives

  • Bugs and Drugs (Alberta Health Services, Alberta, Canada) - “Bugs and Drugs” provides information about antibiotic indications and restrictions, along with microbiology issues.
  • Antimicrobial Stewardship Initiative (Australian Commission on Safety and Quality in Health Care) - The ASI offers online modules for prescribing practices, resources on antimicrobial use, and sample reports for hospitals.
  • Antibiotic Action (The British Society for Antimicrobial Chemotherapy) - Antibiotic Action informs and educates everyone across the globe to identify and implement solutions within research, regulation and economic markets to stimulate and regenerate interest in the discovery and development plus responsible use of new treatments for bacterial infections.
  • Prudent Antibiotic User Website (PAUSE) (British Society for Antimicrobial Chemotherapy and the European Society of Clinical Microbiology and Infectious Diseases) - PAUSE provides standardized teaching materials for more prudent antimicrobial prescribing practices.
  • Transatlantic Task Force on Antimicrobial Resistance (TATFAR) (Centers for Disease Control and Prevention) - TATFAR was created in 2009 with the goal of improving cooperation between the U.S. and the EU in three key areas: (1) appropriate therapeutic use of antimicrobial drugs in medical and veterinary communities, (2) prevention of healthcare and community-associated drug-resistant infections, and (3) strategies for improving the pipeline of new antimicrobial drugs.
  • Antimicrobial Stewardship (European Wound Management Association [EWMA]) - EWMA addresses antimicrobial management and resistance in non-healing wound care.
  • Antimicrobial Stewardship Working Group (International Society of Chemotherapy Infection and Cancer) - The group surveys antimicrobial use and consumption, creates transcontinental consensus documents related to antimicrobial use, and runs online courses for healthcare workers.
  • Antimicrobial Use & Resistance (National Collaborating Centre for Infectious Diseases, Canada) - NCCID provides resources for antimicrobial use in long-term care, surveillance data, and roles of animal and human Health in resistance.
  • Antimicrobial Stewardship  (National Institute for Health and Care Excellence, UK) - NICE’s program provides processes for effective antimicrobial medicine use, tools for implementation, guidance, and online modules.
  • Antimicrobial Stewardship (Public Health Ontario) - Public Health Ontario’s resources provide information on building an antimicrobial stewardship program in a healthcare facility.
  • ReAct Action on Antibiotic Resistance (The ReAct Group at Uppsala University, Sweden) - ReAct aims for change in awareness and action to manage the interacting social, political, ecological and technical forces that drive the rising rate of resistant human and animal infection and the rapid spread of resistance within and between communities and countries.
  • Scottish Antimicrobial Prescribing Group (Scottish Medicines Consortium) - SMC coordinates a national framework for antimicrobial stewardship to enhance the quality of antimicrobial prescribing and management in Scotland.
  • Centre for Antimicrobial Resistance (CAR) (University of Dundee, Scotland, UK) - CAR brings together biologists, chemists, physicists, clinicians, mathematicians, epidemiologists, engineers and designers to focus on innovation in tackling antimicrobial resistance.
  • Review on Antimicrobial Resistance (AMR)  (The Wellcome Trust and Her Majesty's Government) - The independent AMR proposes solutions to the problem of antimicrobial resistance from an economic and social perspective.


Interdisciplinary/Interprofessional Projects

  • Stewardship-Education.org (American Society of Health-System Pharmacists, Infectious Disease Society of America, Making a Difference in Infectious Diseases Pharmacotherapy, National Foundation for Infectious Diseases, Pediatric Infectious Diseases Society, Society for Healthcare Epidemiology of America, Society of Infectious Diseases Pharmacists) - The interdisciplinary project provides online courses; information on antimicrobial use issues including measurement, analysis, special populations, information technology, and infection control; hospital administration and clinical guidelines; policy statements; and relevant research.
  • Antimicrobial Stewardship Programs (Making a Difference in Infectious Diseases [MAD-ID])- The MAD-ID Antimicrobial Stewardship Training Program is designed to help practitioners who are residency trained (or equivalent experience) who are currently or planning to pursue antimicrobial stewardship activities.


Professional Organizations

  • Antimicrobial Stewardship Resources (American Society of Health-System Pharmacists [ASHP]) - ASHP provides a stewardship toolkit, a mentored quality improvement impact program with continuing education activities, and s statement on pharmacists' roles.
  • Antimicrobial Stewardship Toolkit (American Hospital Association) - AHA’s toolkit on antimicrobial stewardship addresses resources for hospitals and health systems, clinicians, and patients.
  • Antimicrobial Stewardship Association for Professionals in Infection Control and Epidemiology (APIC) - APIC provides implementation guides, scientific guidelines, an infection preventionist competency model, and practice resources.
  • Guidelines for Antimicrobial Agent Use (Infectious Diseases Society of America [IDSA])- IDSA’s guidelines cover surgery prophylaxis, stewardship, combat-related infections, neutropenic patients with cancer, outpatient parenteral anti-infective therapy, and indications for vancomycin use.


Academic Centers and Projects

  • Duke Antimicrobial Stewardship Outreach Network (Duke University School of Medicine) DASON’s primary goals are to improve quality of patient care, to enhance patient safety, to promote judicious antimicrobial use (eg, formulary management) for patients treated in community hospitals.
  • Antimicrobial Stewardship Program (Mount Sinai Hospital and University Health Network) - The ASP offers online courses, infection control algorithms, and best health system practices. 
  • Antimicrobial Stewardship (The Ohio State University) - The Antimicrobial Stewardship Program at The Ohio State University, Wexner Medical Center, is a multidisciplinary team consisting of Infectious Diseases physicians, pharmacists, microbiologists, epidemiologists, and a data manager. The goal of ASP is to ensure the selection of the right antibiotic, at the right dose, for the right duration in order to cure infection while minimizing toxicity and emergence of resistance.
  • Penn CDC Prevention Epicenters Program (Penn Medicine)  - The program focuses on use of biomarkers to improve antimicrobial prescribing, colonization with antimicrobial resistant organisms, antimicrobial stewardship strategies, epidemiology of household transmission of methicillin-resistant Staphylococcus aureus (MRSA), treatment of multidrug resistant gram-negative organisms, and strategies to improve the utility of public reporting of healthcare acquired infections.
  • Alliance for the Prudent Use of Antibiotics (Tufts University Medical School) - The alliance lends specialized expertise to guide policy makers, provider organizations, and other stakeholders seeking to improve antimicrobial supply, use, and management decisions.
  • Got A Bug? Antimicrobial Stewardship Program (University of Miami Miller School of Medicine) - Resources encourage clinical stewardship education, reassessment of antimicrobial therapy based on cultures and susceptibilities, de-escalating broad spectrum antimicrobials whenever possible, and stopping antimicrobials when no longer needed.


Health System Programs

  • Antimicrobial Stewardship (Greater New York Hospital Association) - The program helps a group of acute and long term care health facilities implement and test a set of evidence-based guidelines to create effective and sustainable antibiotic stewardship programs across the continuum of care.
  • Antimicrobial Stewardship Program (The Nebraska Medical Center) - Resources include a restricted antimicrobial list, clinical pathways/order sets, institution-specific antibiotic guidelines, and microbiology information.
  • Antimicrobial Stewardship (University of Pennsylvania Health System) - Resources include a restricted antimicrobial list, institution-specific antibiotic guidelines, microbiology information, and other educational material.
  • Antimicrobial Stewardship (Washington State Hospital Association [WSHA]) - The WSHA provides webcasts, sample policies and procedures, strategies specific to critical access hospitals, and report samples.

Recent Literature

Cantey JB, Wozniak PS, Pruszynski JE, et al. Reducing unnecessary antibiotic use in the neonatal intensive care unit (SCOUT): a prospective interrupted time-series study. Lancet Infect Dis 2016 (published online Jul 21)

Castanheira M, Griffin MA, Deshpande LM, et al. Detection of mcr-1 among Escherichia coli clinical isolates collected worldwide as part of the SENTRY Antimicrobial Surveillance Program during 2014-2015. Antimicrob Agents Chemother 2016 (published Jul 11)

Cegielski JP, Kurbatova E, van der Walt M, et al. Multidrug-resistant tuberculosis treatment outcomes in relation to treatment, initial and acquired second-line drug resistance. Clin Infect Dis 2015 (published online Oct 27)

Chou AF, Graber CJ, Jones M, et al. Characteristics of antimicrobial stewardship programs at Veterans Affairs hospitals: results of a nationwide survey. Infect Control Hosp Epidemiol 2016 (published online Feb 24)

Corey VC, Lukens AK, Istvan ES, et al. A broad analysis of resistance development in the malaria parasite. Nat Commun 2016 (published online Jun 15)

Cunha CB, Kassakian SZ, Chan R, et al. Screening of nursing home residents for colonization with carbapenem-resistant Enterobacteriaceae admitted to acute care hospitals: incidence and risk factors. Am J Infect Control 2015 (published online Nov 26)

Dar OA, Hasan R, Schlundt J, et al. Exploring the evidence base for national and regional policy interventions to combat resistance. Lancet 2015 (published online Nov 18)

Deak D, Outterson K, Powers JH, et al. Progress in the fight against multidrug-resistant bacteria? A review of U.S. Food and Drug Administration-approved antibiotics, 2010-2015. Ann Intern Med 2016 (published online May 31)

Di Pilato V, Arena F, Tascini C, et al. MCR-1.2: a new MCR variant encoded by a transferable plasmid from a colistin-resistant KPC carbapenemase-producing Klebsiella pneumoniae of sequence type 512. Antimicrob Agents Chemother 2016 (published Jul 11)

Diaz A, Ortiz DC, Trujillo M, et al. Clinical characteristics of carbapenem-resistant Klebsiella pneumoniae infections in ill and colonized children in Colombia. Pediatr Infect Dis J 2016 Mar;35(3):237-41

Dodd PJ, Sismanidis C, Seddon JA. Global burden of drug-resistant tuberculosis in children: a mathematical modelling study. Lancet Infect Dis 2016 (published online Jun 21)

Du H, Chen L, Tang YW, et al. Emergence of the mcr-1 colistin resistance gene in carbapenem-resistant Enterobacteriaceae. (Letter) Lancet Infect Dis 2016 (published online Jan 31)

EFSA/ECDC. The European Union summary report on antibicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2014. EFSA J 2016 (published online Feb 11)

Falgenhauer L, Waezsada SE, Yao Y, et al. Colistin resistance gene mcr-1 in extended-spectrum beta-lactamase-producing and carbapenemase-producing Gram-negative bacteria in Germany.  (Letter) Lancet Infect Dis 2016 (published online Jan 8)

Furin J, Brigden G, Lessem E, et al. Global progress and challenges in implementing new medications for treating multidrug-resistant tuberculosis. Emerg Infect Dis 2016 (published online Jan 27)

Glaser P, Martins-Simoes P, Villain A, et al. Demography and intercontinental spread of the USA300 community-acquired methicillin-resistant Staphylococcus aureus lineage. mBio 2016 Feb 16;7(1):e02183-15

Goodman KE, Lessler J, Cosgrove SE, et al. A clinical decision tree to predict whether a bacteremic patient is infected with an ESBL-producing organism. Clin Infect Dis 2016 (published online Jun 28)

Goto M, O'Shea AMJ, Livorsi DJ, et al. The effect of a nationwide infection control program expansion on hospital-onset gram-negative rod bacteremia in 130 Veterans Health Administration medical centers: an interrupted time series analysis. Clin Infect Dis 2016 (published online Jun 28)

Grami R, Mansour W, Mehri W, et al. Impact of food animal trade on the spread of mcr-1-mediated colistin resistance, Tunisia, July 2015. Euro Surveill 2016 Feb 25;21(8):pii=30144

Guh AY, Bulens SN, Mu Y, et al. Epidemiology of carbapenem-resistant Enterobacteriaceae in 7 US communities, 2012-2013. JAMA 2015 (published online Oct 5)

Gulliford MC, Moore MV, Little P, et al. Safety of reduced antibiotic prescribing for self limiting respiratory tract infections in primary care: cohort study using electronic health records. BMJ 2016 (published online Jul 4)

Haenni M, Poirel L, Kieffer N, et al. Co-occurrence of extended spectrum beta lactamase and mcr-1 encoding genes on plasmids. (Letter) Lancet Infect Dis (published online Jan 8)

Hallsworth M, Chadborn T, Sallis A, et al. Provision of social norm feedback to high prescribers of antibiotics in general practice: a pragmatic national randomised controlled trial. Lancet 2016 (published online Feb 18)

Hanley PW, Barnhart KF, Abee CR, et al. Methicillin-resistant Staphylococcus aureas prevalence among captive chimpanzees, Texas USA, 2012. Emerg Infect Dis 2015 (published online Oct 29)

Harik NS, Com G, Tang X, et al. Clinical characteristics and epidemiology of methicillin-resistance Staphylococcus aureus (MRSA) in children with cystic fibrosis from a center with a high MRSA prevalence. Am J Infect Control 2015 (published online Dec 9)

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