The Osterholm Quotes

"It is probable that human cases of CWD associated with the consumption of contaminated meat will be documented in the years ahead. It is possible that number of human cases will be substantial and will not be isolated events."
"If Stephen King could write an infectious disease novel, he would write about prions like this."
"What our work will be doing is bringing together the world’s expertise, whether they’re at the World Health Organization or the Centers for Disease Control and Prevention or the NIH. And we will really serve as you might say 'air traffic control' on a global level for trying to develop new and better flu vaccinations."
"No one should assume that this means there's going to be this new universal flu vaccine in the next several years. This is going to take a lot of work. It's going to take billions of dollars and research that will be considered cutting edge at the time it's done and doesn't exist yet today. But we're optimistic that we can have a [universal] flu vaccine."
"Influenza, and particularly pandemic influenza, remains one of the greatest global health challenges today, and the results of this project will go a long way toward reducing these risks."
"By highlighting key research gaps, identifying strategic goals and milestones and encouraging synergistic R&D [research and development] activities, the roadmap will serve as a valuable tool to advance a complex field of vaccine research and stimulate informed investment in influenza vaccine R&D."
"Frankly, if the Chinese want to go to war with us, they wouldn't have to fire a single shot. They would just shut down the drug distribution overnight."
"What we are doing now is working backward, looking at the entire global supply chain for these products."
"We don't pretend we're going to fix [supply chain issues] yet. We've just got to get people to understand the vulnerability."
"We know, based on our recent experience, that there will be more and more incidents where necessary drugs or medical supplies will be unavailable to those in crisis and, increasingly, the consequences are truly about life and death."
"I do believe that it is not a matter of if, but when, CWD crosses to humans."
"It's way too early to tell how effective this year's [flu] vaccine is." However, regarding timing, "Now's a great time, go get it today."
"It's very possible and maybe likely that there may be other enteroviruses [aside from D68] that are causing similar symptoms. This is a tough disease, because it doesn't fit a model of strict cause and effect."
"I don't know if that's what did it [awareness of last season's severe flu season] or if in fact there are more organized programs to get people vaccinated."
"What makes us quite convinced that this is actually an infectious process is that these cases are not located only in one area ... and if you look at the seasonality, it's very, very striking to see that the vast majority of cases that have occurred since 2014 have occurred in the months of basically August and September and then coming back down in October ... It has all the makings of being an enterovirus-like agent or agents."
"We are beginning to sit on the cliff edge of a post-antibiotic era. This is not just about a problem today, it's about a problem that our kids and grandkids are going to bear in a very big way."
"We're seeing rapid testing becoming much more of a reality — a faster and more specific diagnostic result could help bring better outcomes for your patients and your institution."
"The use of vaccines to curb antibiotic use has tremendous potential as an alternative approach to prevent and treat infections of resistant organisms. . . . If we had vaccines, we wouldn't have to deal with the actual infection and the potential for resistance."
"I don't want to say that there won't be new antibiotics developed, but they won't be the savior against antibiotic resistance. We must save the antibiotics we have now and ensure we use them as wisely as possible."
"Antimicrobial resistance is as much a part of our world as gravity. We've overprescribed and overused antibiotics over the past 100 years, so we shouldn't be surprised today that we're seeing resistance challenges as these microbes evolve to survive."
"We don't do much better with cytokine storms today than we did back in [the flu pandemic of] 1918. There are some machines that can breathe and circulate blood for you, but overall the outcome is still very, very bleak."
"If a pandemic causes disruption in the production and transportation of these [critical life-saving] drugs, we'll see people dying in short order. Collateral damage from a 1918-like pandemic could be dramatic."
"We already overwhelmed the healthcare system here in the US with just the seasonal flu this year [in 2017-18], and this wasn't even a particularly severe year. But it shows you just how limited our capacity is to respond to a major increase in cases."
"Influenza pandemics are like earthquakes, hurricanes, and tsunamis: they occur, and some are much worse than others. The idea that we would not have another 1918-like event is foolish. For all we know, it could be starting as we speak."
"Since 95 percent of flu outbreaks start in mid-December, it’s best to get the flu shot in early to mid-November."

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