"What we really need is a new [influenza] vaccine. What we’re doing is tinkering—but I don't know how to tinker with this current vaccine and make it any better. It's like we're trying to fix a horse and buggy when what we really need is a modern 2015 vehicle."
"Extreme measures are needed to ensure a massive coordinated effort among vaccine manufacturers, government regulatory authorities, government public health agencies, non-governmental organizations and global, national and local leaders."
"We had very bad matches [of vaccine to circulating flu viruses] and the vaccine performed as we would expect on an average basis, and we've had years where there's been a really good match and the vaccine provided little to no protection."
"I still say get your flu shot, it's the best tool that we have. But . . . there just is no comprehensive, compelling data that say when you get your flu shot that it even reduces the severity of illness or hospitalization."
"This is potentially revolutionary work. We're a long way from changing our current policies, but this could really help. It also raises questions about how often do we need to be vaccinated if we can use this back-boost?"
"We need a lot more information about the virology, the clinical presentation and the epidemiology of this virus [Ebola]. Nobody underestimates the difficulty of doing that research in these settings, but it is really important to get this information."
"These are a major step forward in protecting workers from Ebola virus infection . . . but the recommendations just by themselves do not make for a safer work environment. . . . Training is critical. We need to train people how to use PPE safely and effectively."
"The Ebola epidemic in West Africa could become an inflection point for fundamental reform of the WHO and usher in an era of direct United Nations engagement in health threats that could potentially destabilize nations and regions."
"The key piece here is early recognition of an infection. Will people make the connection between travel to West Africa and the possibility the illness the patient is being seen for is due to the Ebola virus?"