A chikungunya candidate vaccine developed using noninfectious virus-like particles (VLPs) has been shown to provide long-term protection against multiple genotypes of the disease, according to results of the first human trial, conducted by researchers from the National Institute of Allergy and Infectious Diseases (NIAID) and published today in The Lancet.
The number of travel-related US chikungunya cases has grown to 580, an increase of 96 in the past week, the Centers for Disease Control and Prevention (CDC) said today in its weekly update. The number of locally acquired cases stayed at 4, for 584 total US cases.
Officials reported more than 62,000 new chikungunya cases in the Caribbean and surrounding areas last week—almost all in the Dominican Republic—expanding the outbreak to 576,000 cases, according to an Aug 8 update from the Pan American Health Organization (PAHO).
This year's tally of US chikungunya cases related to foreign travel, mostly to the Caribbean, has risen to 484, an increase of 86 over the past week, the Centers for Disease Control and Prevention (CDC) says.
Forty states have reported cases, three more than a week ago, the agency said in an Aug 5 update. The number of locally acquired cases stayed at four, all of them in Florida.
About two thirds of the 38,000 new cases reported last week were in the Dominican Republic.
Resistance to artemisinin, the main drug for treating malaria, has now spread throughout Southeast Asia, including critical border regions, and a genetic mutation in the Plasmodium falciparum parasite that causes the disease may be the culprit, according to a study today in the New England Journal of Medicine.
The steady flow of imported chikungunya infections linked mainly to travel to the Caribbean continued in the United States last week, with 98 more cases reported, lifting the total to 398, the US Centers for Disease Control and Prevention (CDC) said yesterday.
Cases in the Americas now total almost 475,000, with the Dominican Republic accounting for most of last week's rise.
The chikungunya epidemic in the Caribbean is continuing to spill over into the United States, with 300 imported cases identified as of yesterday, an increase of 66 from a week earlier, according to the Centers for Disease Control and Prevention (CDC).
The increase was led by the Dominican Republic, which had almost 60,000 new cases.
