But the researchers say other genetic mutations would likely be needed for the virus to prefer human cell receptors and enable efficient human transmission.
The loss of activity is equivalent to 15% of the US population becoming completely immobile for 1 day.
Adult COVID-19 patients also infected with the flu are 4 times more likely to need mechanical ventilation and 2.4 times more likely to die.
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They also had lower odds of requiring intensive care and dialysis or vasopressors than those who didn't receive early therapy, the authors say.
With flu and COVID levels still low but expected to rise, the CDC said vaccination is a good way to cut risk over the holiday season.
In 2017-18, 70% to 86% of hospitalized children with flu received antivirals, declining to 52% to 59% in 2023-24.
The average time between discharge and death was 9 days.
The proportion admitted to the ICU ranged from 14% during 2021-22 to 22% during 2013-14.
Though the KP.3.1.1 variant is still dominant, levels of the newer XEC variant continue to rise.
The CDC said the rise in M pneumoniae in children ages 2 to 4 is notable, because it isn't typically known as a leading cause of pneumonia in the age-group.
Less than half recognized some of the most common infant RSV symptoms.
CDC wastewater tracking shows SARS-CoV-2 detections are now at the low level nationally.
The test joins other over-the-counter COVID-19/flu tests already available under emergency use authorization.
