The findings could help hospitals and public health officials prepare for outbreaks.
The loss of activity is equivalent to 15% of the US population becoming completely immobile for 1 day.
Adult COVID-19 patients also infected with the flu are 4 times more likely to need mechanical ventilation and 2.4 times more likely to die.
The roadmap offers a powerful opportunity to leverage advances in vaccine science to better protect against influenza, including pandemic flu.
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Overall flu cases are 10.8% higher than last year across Australia.
Japan typically reports increased influenza activity at the end of November.
HEPA purifiers were associated with a 33% decrease in viral diversity, but the reduction wasn't linked to fewer school absences.
But there is 'substantial opportunity' for load-balancing strategies during future pediatric hospital surges to reduce bed strain and harm, the authors say.
The money will fund work on CD388, a non-vaccine preventive for both pandemic and seasonal flu.
In other developments, the CDC reported one more pediatric flu death, raising the season's total to 281, the highest for a nonpandemic year.
The reports provide more detail on the deadliest flu season for US children in more than a decade.
Commonly detected viruses were rhinovirus/enterovirus, seasonal coronavirus, human metapneumovirus, and SARS-CoV-2.
The 2024-25 season was the highest severity flu season in more than a decade, according to a new analysis of US surveillance data.
Test positivity is down slightly, but emergency department visits for COVID are elevated in children.