The delay, narrowed approval, and extra study steps raise concerns about the status of and potential added requirements for other COVID vaccines.
Plaque growth can lead to a higher risk of heart attack, stroke, and other life-threatening cardiovascular events for as long as 1 year.
Post-exertional malaise, or exercise intolerance, was seen in 36% of those with long COVID.
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The authors found no differences among the study participants in time to recovery.
The authors noted that misinformation can erode public trust in scientists, which complicates disease-control efforts.
While most studies have looked at the pandemic’s impact on elementary school kids or teenagers, little attention has been paid to preschool-aged kids.
Risk factors for long COVID were Black race, ages 50 to 64, diabetes, and severe infection.
The extra dose reduced risk of infection by 41%, hospitalization or death by 65%.
The findings highlight the importance of preventing COVID-19 through vaccination and contact precautions, the authors said.
The researchers limited capture of data on COVID-19 diagnoses to children who had an additional respiratory illness, such as pneumonia.
The absolute difference in age-adjusted death rates between men and women increased from 252 to 315 per 100,000 from 2010 to 2021.
Outcomes were compared to those seen in the 4 years prior to the pandemic.
Outcomes of nosocomial SARS-CoV-2 infections are important metrics for hospital prevention and control measures.