Clostridium difficile

Recent News

Jun 20, 2022

Stewardship / Resistance Scan for Jun 20, 2022

Cascade susceptibility reporting
Sporicidal cleaning for C diff
May 27, 2022
Mom holding capsules with boy at computer

Inappropriate antibiotics for kids tied to adverse events, higher costs

"Seeing the numbers really does crystallize the urgency of this issue."

May 20, 2022

Stewardship / Resistance Scan for May 20, 2022

C difficile rates during COVID-19
Students pressuring for antibiotics
May 12, 2022

News Scan for May 12, 2022

High-path avian flu in Minnesota fox
Hospital C difficile intervention
Apr 25, 2022

Stewardship / Resistance Scan for Apr 25, 2022

Antibiotic resistance rise during COVID
C difficile in pigs
South African center for antibiotic discovery
Apr 15, 2022

Stewardship / Resistance Scan for Apr 15, 2022

Vaccine hesitancy and poor antibiotic knowledge
Short-course antibiotics for BSI
C difficile on potatoes
Apr 13, 2022

Stewardship / Resistance Scan for Apr 13, 2022

Antibiotic-resistant Campylobacter
Household C diff spread
Feb 23, 2022

Stewardship / Resistance Scan for Feb 23, 2022

C diff in hospital rooms
XDR Shigella increase in Europe
Jan 24, 2022

Stewardship / Resistance Scan for Jan 24, 2022

Non-adherence to C diff guidelines
Pandemic decline in urgent care antibiotics
Jan 21, 2022

Stewardship / Resistance Scan for Jan 21, 2022

Oral microbiome therapy for C diff
Funding for new TB treatments

Resources & Literature

Recent Literature

Abosi OJ, Kobayashi T, Holley S, et al. Stable Clostridioides difficile infection rates after the discontinuation of ultraviolet light for terminal disinfection at a tertiary care center, Iowa 2019–2020. Am J Infect Control 2021 (published online Aug 13)

Carling PC, O'Hara LM, Harris AD, et al. Mitigating hospital-onset Clostridioides difficile: the impact of an optimized environmental hygiene program in eight hospitals. Infect Control Hosp Epidemiol 2022 (published online Jun 20)

Carlson TJ, Gonzalez-Luna AJ, Wilcox MF, et al. Corticosteroids do not increase the likelihood of primary Clostridioides difficile infection in the setting of broad-spectrum antibiotic use. Open Forum Infect Dis 2021 (published online Aug 11)

Evans ME, McCauley BP, Simbartl LA. Association between Clostridioides difficile infection testing results and decision to treat. Infect Control Hosp Epidemiol 2021 (published online Jul 30)

Gonzales-Luna AJ, Olaitan AO, Shen WJ, et al. Reduced susceptibility to metronidazole is associated with initial clinical failure in Clostridioides difficile infection. Open Forum Infect Dis 2021 (published online Jul 8)

Goodenough D, Sefton S, Overton E, et al. Reductions in positive Clostridioides difficile events reportable to National Healthcare Safety Network (NHSN) with adoption of reflex enzyme immunoassay (EIA) testing in 13 Atlanta hospitals. Infect Control Hosp Epidemiol 2021 (published online Jul 8)

Guo CLT, Kwong TNY, Mak JWY, et al. Trends in incidence and clinical outcomes of Clostridioides difficile infection, Hong Kong. Emerg Infect Dis 2021 December;27(12):3036-44

Kim DY, Lee YM, Park KH, et al. Clostridium difficile infection after orthopedic surgery: incidence, associated factors, and impact on outcome. Am J Infect Control 2021 (published online Aug 22)

Lawrence J, Kitchin N, Anderson AS, et al. Safety and immunogenicity of different Clostridioides (Clostridium) difficile vaccine formulations in two early phase randomized studies of healthy adults aged 50–85 years. Vaccine 2021 (published online Sep 3)

Maro A, Asrat H, Qiu W, et al. Trends in Clostridioides difficile infection across a public health hospital system in New York City 2019-2021: a cautionary note. Am J Infect Control 2022 (published online May 12)

Nace ME, Wallace JL, Kline KE, et al. Notes from the field: Escherichia coli O157:H7 outbreak in children with Clostridioides difficile colonization associated with an improperly treated swimming pool—Pennsylvania, June 2021. MMWR Morb Mortal Wkly Rep 2022 May 20;71:690-1

Perry DA, Shirley D, Micic D, et al. External validation and comparison of Clostridioides difficile severity scoring systems. Clin Infect Dis 2021 (published online Aug 30)

Phillips EC, Warren CA, Ma JZ, et al. Impact of tigecycline on C. difficile outcomes: case series and propensity-matched retrospective study. Antimicrob Agents Chemother 2022 (published online Jun 1)

Tougas SR, Lodha N, Vandermeer B, et al. Prevalence of detection of Clostridioides difficile among asymptomatic children. JAMA Pediatr 2021 (published online Aug 2)

Yu H, Alfred T, Nguyen JL, et al. Incidence, attributable mortality, and healthcare and out-of-pocket costs of Clostridioides difficile infection in US medicare advantage enrollees. Clin Infect Dis 2022 (published online Jun 10)

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