Clostridium difficile

Recent News

May 07, 2021

Stewardship / Resistance Scan for May 07, 2021

Antibiotic use and hospital C diff
Antibiotic use in rural China
Apr 16, 2021

News Scan for Apr 16, 2021

Antibiotic use in re-hospitalized MRSA patients
H1N1v flu case in Wisconsin
Polio in 10 countries
Feb 26, 2021
Meeting of doctors aerial view

National safety program linked to reduced hospital antibiotic use

In addition to less antibiotic use, participating hospitals saw a 20% drop in hospital-onset C difficile.

Feb 25, 2021

Stewardship / Resistance Scan for Feb 25, 2021

C diff and acid-reducing drugs
AMR social science research
Feb 23, 2021
Colon imaging

Study supports fluoroquinolone-sparing treatment for diverticulitis

Data indicate amoxicillin-clavulanate is safe and effective and may cut the risk of fluoroquinolone-related harms.

Dec 07, 2020

News Scan for Dec 07, 2020

Drop in healthcare-related infections
Avian flu outbreaks in 4 nations
Oct 27, 2020

Stewardship / Resistance Scan for Oct 27, 2020

C diff guidelines for low-income countries
COVID-19 antibiotic stewardship
Oct 15, 2020

Stewardship / Resistance Scan for Oct 15, 2020

MDR infection risks study
C difficile pacemaker infection
Sep 28, 2020

News Scan for Sep 28, 2020

Southern Hemisphere flu vaccine strains
New antibiotic for hospital pneumonia
Durable fecal transplant effectiveness
CDC ends Cyclospora probe
Sep 16, 2020

Stewardship / Resistance Scan for Sep 16, 2020

C diff vaccine candidate fails phase 3
Prior patient cultures for better antibiotics Rx

Resources & Literature

Recent Literature

Abdali Z, Roberts T, Barton P, et al. Economic evaluation of faecal microbiota transplantation compared to antibiotics for the treatment of recurrent Clostridioides difficile infection. EClinicalMedicine 2020 Jul 1;24:100420

Alimings C, Riley TV. Antibiotics and healthcare facility-associated Clostridioides difficile infection: systematic review and meta-analysis 2020 update. J Antimicrob Chemother 2021 (published online Mar 31)

Anjewierden S, Han Z, Brown AM, et al. Risk factors for Clostridioides difficile colonization among hospitalized adults: a meta-analysis and systematic review. Infect Control Hosp Epidemiol 2020 (published online Oct 29)

Aukes L, Fireman B, Lewis E, et al. A risk score to predict Clostridioides difficile infection. Open Forum Infect Dis 2021 (published online Feb 4)

Babar S, El Kurdi B, El Iskandarani M, et al. Oral vancomycin prophylaxis for the prevention of Clostridium difficile infection: a systematic review and meta-analysis. Infect Control Hosp Epidemiol 2020 (published online Jun 29)

Banks M, Phillips AB. Evaluating the effect of automated hand hygiene technology on compliance and C. difficile rates in a long-term acute care hospital. Am J Infect Control 2020 (published online Nov 10)

Bentivegna E, Alessio G, Spuntarelli V, et al. Impact of COVID-19 prevention measures on risk of health care-associated Clostridium difficile infection. Am J Infect Control 2020 (published online Oct 5)

Bhoi B, Wong KK, Dunn AN, et al. Real-time polymerase chain reaction (PCR) cycle threshold and Clostridioides difficile infection outcomes. Infect Control Hosp Epidemiol 2021 (published online Feb 24)

Carlson TJ, Gonzales-Luna AJ, Nebo K, et al. Assessment of kidney injury as a severity criteria for Clostridioides difficile infection. Open Forum Infect Dis 2020 (published online Oct 7)

Carlson TJ, Gonzales-Luna AJ. Utilizing antibiotics to prevent Clostridioides difficile infection: does exposure to a risk factor decrease risk? J Antimicrob Chemother 2020 (published online Jul 22)

Chen J, Gong CL, Hitchcock MM, et al. Cost-effectiveness of bezlotoxumab and fidaxomicin for initial Clostridioides difficile infection. Clin Microbiol Infect 2021 (published online Apr 16)

Clayton JA, Cadnum JL, Senders S, et al. Degree of concordance of Clostridioides difficile strains in adults with community-associated C. difficile infection and infants with C. difficile colonization. Infect Control Hosp Epidemiol 2020 (published online Nov 19)

Collier DA, De Marco A, Ferreira IA, et al. Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies. Nature 2021 (published online Mar 11)

Collison M, Murillo C, Marrs R, et al. Universal screening for Clostridioides difficile at an urban academic medical center. Infect Control Hosp Epidemiol 2020 (published online Sep 22)

Davies K, Mawer D, Walker AS, et al. An analysis of C.difficile environmental contamination during and following treatment for C.difficile infection. Open Forum Infect Dis 2020 (published online Aug 17)

De Bruyn G, Gordon DL, Steiner T, et al. Safety, immunogenicity, and efficacy of a Clostridioides difficile toxoid vaccine candidate: a phase 3 multicentre, observer-blind, randomised, controlled trial. Lancet 2020 (published online Sep 15)

Deane J, Fouhy F, Ronan NJ, et al. A multicentre analysis of Clostridium difficile in persons with cystic fibrosis demonstrates that carriage may be transient and highly variable with respect to strain and level. J Infect 2021 (published online Jan 11)

Doll M, Marra AR, Apisarnthanarak A, et al. Prevention of Clostridioides difficile in hospitals: a position paper of the International Society for Infectious Diseases. Int J Infect Dis 2020 (published online Oct 26)

Doolan CP, Louie T, Lata C, et al. Latent class analysis for the diagnosis of Clostridioides difficile infection. Clin Infect Dis 2020 (published online Oct 14)

Hazel K, Skally M, Glynn E, et al. The other ‘C’: hospital-acquired Clostridioides difficile infection during the COVID-19 pandemic. Infect Control Hosp Epidemiol 2021 (published online Jan 13)

Heil EL, Harris AD, Brown CH, et al. A multi-center evaluation of probiotic use for the primary prevention of Clostridioides difficile infection. Clin Infect Dis 2021 (published online May 10)

Inghammar M, Svanstrom H, Voldstedlund M, et al. Proton-pump inhibitor use and the risk of community-associated Clostridium difficile infection. Clin Infect Dis 2021 (published online Feb 25)

Janezic S, Blazevic I, Eyre DW, et al. Possible contribution of shoes to Clostridioides difficile transmission within the hospitals. Clin Microbiol Infect 2020 (published online Nov 6)

Kazakova SV, Baggs J, Yi SH, et al. Associations of facility-level antibiotic use and hospital-onset Clostridioides difficile infection in US acute-care hospitals, 2012-2018. Infect Control Hosp Epidemiol 2021 (published online May 7)

Keegan J, Buchan BW, Ledeboer NA, et al. Toxigenic Clostridioides difficile colonization as a risk factor for development of C. difficile infection in solid-organ transplant patients. Infect Control Hosp Epidemiol 2020 (published online Sep 16)

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