Clostridium difficile

Recent News

Jun 29, 2020
Extended family playing board game

Study suggests household exposure may increase C difficile risk

Living with a family member with C difficile increased the risk of contracting the disease 12-fold.

May 22, 2020

News Scan for May 22, 2020

C diff in COVID-19 patients
Pharmacist review for Staph bacteremia
Romaine E coli and cattle proximity
Polio in Afghanistan, Pakistan
May 18, 2020

Stewardship / Resistance Scan for May 18, 2020

Funding for recurrent C diff drug
Antibiotic decline in Spain
May 11, 2020

Stewardship / Resistance Scan for May 11, 2020

Nursing home stewardship for UTIs
Funds for rapid susceptibility test
Acid suppressors and C diff
Apr 29, 2020

News Scan for Apr 29, 2020

New DRC Ebola case
Impact of C diff treatment guidelines
Nigeria Lassa decline
Apr 13, 2020

Stewardship / Resistance Scan for Apr 13, 2020

C diff testing stewardship
Improved UK antibiotic prescribing
Apr 02, 2020
ESBL bacteria

CDC studies show drop in MDR bacteria, C diff in US hospitals

The findings suggest that prevention efforts, particularly in hospitals, are yielding benefits.

Mar 19, 2020

Stewardship / Resistance Scan for Mar 19, 2020

Antibiotic allergies in Aussie nursing homes
Drug for recurrent C diff
Mar 18, 2020

News Scan for Mar 18, 2020

C diff testing intervention
Carbapenem heteroresistance
Lassa fever in Nigeria
Mar 13, 2020
Fecal transplant pills

FDA warns about infections linked to fecal microbiota transplants

The alert comes after 6 patients were infected with diarrhea-causing E coli following FMT.

Resources & Literature

Recent Literature

Abad CL, Barker AK, Safdar N. A systematic review of the effectiveness of cohorting to reduce transmission of healthcare-associated C. difficile and multidrug-resistant organisms. Infect Control Hosp Epidemiol 2020 (published online Mar 27)

Abdali Z, Roberts T, Barton P, et al. Economic evaluation of faecal microbiota transplantation compared to antibiotics for the treatment of recurrent Clostridioides difficile infection. EClinicalMedicine 2020 Jul 1;24:100420

Aguirre-Garcia GM, Garza-Gonzalez E, Morfin-Otero R, et al. Clostriodioides difficile infections among healthcare workers. Am J Infect Control 2020 (published online Feb 28)

Al-Tawfiq JA, Rabaan AA, Bazzi AM, et al. Clostriodioides (Clostridium) difficile-associated disease: epidemiology among patients in a general hospital in Saudi Arabia. Am J Infect Control 2020 (published online Feb 29)

Avni T, Babitch T, Ben-Zvi H, et al. Clostridioides difficile infection in immunocompromised hospitalized patients is associated with a high recurrence rate. Int J Infect Dis 2019 (published online Oct 28)

Babar S, El Kurdi B, El Iskandarani M, et al. Oral vancomycin prophylaxis for the prevention of Clostridium difficile infection: a systematic review and meta-analysis. Infect Control Hosp Epidemiol 2020 (published online Jun 29)

Baron SW, Ostrowsky BE, Nori P, et al. Screening of Clostridioides difficile carriers in an urban academic medical center: understanding implications of disease. Infect Control Hosp Epidemiol 2019 (published online Dec 11)

Berger FK, Mellmann A, Bischoff M, et al. Molecular epidemiology and antimicrobial resistance of Clostridioides difficile detected in chicken, soil and human samples from Zimbabwe. Int J Infect Dis 2020 (published online Apr 17)

Bilgin J, Sayin E, Gurun HP, et al. Hospital acquired Clostridioides difficile infection and risk factors for severity in a university hospital: a prospective study. Am J Infect Control 2020 (published online Jun 5)

Brown KA, McGeer A, Schwartz KL, et al. Interfacility patient sharing and Clostridioides difficile infection incidence in the Ontario hospital system: a 13-year cohort study. Infect Control Hosp Epidemiol 2019 (published online Nov 25)

Bush K, Barbosa H, Farooq S, et al. Predicting hospital-onset Clostridium difficile using patient mobility data: a network approach. Infect Control Hosp Epidemiol 2019 (published online Oct 28)

Chiang HY, Huang HC, Chung CW, et al. Risk prediction for 30-day mortality among patients with Clostridium difficile infections: a retrospective cohort study. Antimicrob Resist Infect Control 2019 Nov 12;8:175

Clancy CJ, Buehrle D, Vu M, et al. Impact of revised Infectious Diseases Society of America and Society for Healthcare Epidemiology of America clinical practice guidelines on the treatment of Clostridium difficile infections in the United States. Clin Infect Dis 2020 (published online Apr 28)

Cohen BV, Levine M, Kamboj M. Clostridium difficile infection following outpatient cancer surgery. Infect Control Hosp Epidemiol 2019 (published online Oct 14)

Colomb-Cotinat M, Assouvie L, Durand J, et al. Epidemiology of Clostridioides difficile infections, France, 2010 to 2017. Euro Surveill 2019 Aug 29;24(35):pii=1800638

Crobach MJT, Notermans DW, Harmanus C, et al. Community-onset Clostridioides difficile infection in hospitalized patients in the Netherlands. Open Forum Infect Dis 2019 (published online Nov 26)

Dai W, Yang T, Yan L, et al. Characteristics of Clostridium difficile isolates and the burden of hospital-acquired Clostridium difficile infection in a tertiary teaching hospital in Chongqing, Southwest China. BMC Infect Dis 2020 Apr 15;20(277)

Dbeibo L, Kelley K, Beeler C, et al. Achieving Clostridioides difficile infection Health and Human Services 2020 goals: using agile implementation to bring evidence to the bedside. Infect Control Hosp Epidemiol 2019 (published online Dec 5)

Doll ME, Zhao J, Kang L, et al. Chasing the rate: an interrupted time series analysis of interventions targeting reported hospital onset Clostridioides difficile, 2013–2018. Infect Control Hosp Epidemiol 2020 (published online Jun 4)

Duhalde L, Lurienne L, Wingen-Heimann SM, et al. The economic burden of Clostridioides difficile infection in patients with hematological malignancies in the United States: a case-control study. Infect Control Hosp Epidemiol 2020 (published online May 15)

Gilboa M, Levi EH, Cohen C, et al. Environmental shedding of toxigenic Clostridioides difficile by asymptomatic carriers: a prospective observational study. Clin Microbiol Infect 2020 (published online Jan 2)

Guh AY, MU Y, Winston LG, et al. Trends in U.S. burden of Clostridioides difficile infection and outcomes. N Engl J Med 2020 Apr 2;382:1320-30

Hatt S, Schindler B, Bach D, et al. Washer disinfector and alkaline detergent efficacy against C. difficile on plastic bedpans. Am J Infect Control 2020 (published online Jan 5)

Hecker MT, Son AH, Alhmidi H, et al. Efficacy of a stewardship intervention focused on reducing unnecessary use of non-Clostriodioides difficile antibiotics in patients with Clostridioides difficile infection. Infect Control Hosp Epidemiol 2019 (published online Dec 17)

Hengel RL, Ritter TE, Nathan RV, et al. Real-world experience of bezlotoxumab for prevention of Clostridioides difficile infection: a retrospective multicenter cohort study. Open Forum Infect Dis 2020 (published online Mar 19)

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