MERS-CoV

Middle East respiratory syndrome coronavirus

Recent News

May 05, 2020

News Scan for May 05, 2020

COVID-19 vaccine trial
MERS in Saudi Arabia
Flu vaccine dosing in kids
Apr 21, 2020

News Scan for Apr 21, 2020

Phase 1 trials of MERS vaccines
Risk of flu death by age
Apr 10, 2020

News Scan for Apr 10, 2020

New DRC Ebola case
Three Saudi MERS cases
Polio in 4 nations
Apr 09, 2020

News Scan for Apr 09, 2020

MERS in Saudi Arabia
Flu vaccine effectiveness
Mar 20, 2020

News Scan for Mar 20, 2020

Uptick in US visits for flulike illness
E coli sproutbreak
Ebola in DRC
3 Saudi MERS cases
Polio in 5 countries
Mar 17, 2020

News Scan for Mar 17, 2020

Saudi MERS cases
Flu-related hospital readmission
Global flu decrease
Mar 13, 2020

News Scan for Mar 13, 2020

US flu levels rise a bit
Ebola milestone in DRC
MERS case in Qatar
Polio cases in 4 nations
San Fran meat antibiotics ordinance
Mar 09, 2020

News Scan for Mar 09, 2020

New Saudi MERS cases
Bias in flu case definitions
Mar 05, 2020

News Scan for Mar 05, 2020

More MERS in Saudi Arabia
Drug trial for highly resistant TB
Urine culture order intervention
Antibiotic use, resistance in African food animals
Mar 04, 2020

News Scan for Mar 04, 2020

New Saudi MERS case
Avian flu in Taiwan, Bulgaria

Resources & Literature

Resources

 

Jump to Recent Literature

 

Last updated Oct 8, 2014

Latest Cases & General Information

Frequently updated case list from FluTrackersTransmission electron micrograph of Middle East Respiratory Syndrome Coronavirus
Disease outbreak news from WHO
Maia Majumder, MPH, MERS resources on Tumblr
Virology Down Under MERS-CoV page
Naming of MERS-CoV from Science (May 6, 2013)
Genetic sequence of MERS-CoV from PHE

Health Agency Documents

World Health Organization (WHO)

MERS-CoV page 
List of latest case updates
Summary updates landing page
Latest risk assessment (Apr 24, 2014)
Frequently asked questions (May 9, 2014)
Interim Case Definitions (Jul 14, 2014)
Guidance on conducting case-control studies (Jul 15, 2014)
Interim surveillance recommendations (Jun 27, 2013)
Interim recommendations for laboratory testing (Sep 16, 2o13)
Seroepidemiological investigation of contacts (Nov 19, 2013)                                                                     Risk factors of infection among health care personnel (Jan 27, 2014)
Guidance for health care professionals (May 6, 2013)
Clinical management (Feb 11, 2013)
Home care for patients with MERS-CoV infection (Aug 8, 2013)
Travel recommendations (Jun 5, 2013)
Travel advice for pilgrims (Jun 3, 2014)
Naming of the novel coronavirus (May 28, 2013)

US Centers for Disease Control and Prevention (CDC)

MERS-CoV page
Press release on first US case
(May 2, 2014)
Press release on clearing of contacts of first 2 US cases (Jun 17, 2014)
Health Alert Network advisory (May 3, 2014)
Frequently asked questions
(Aug 4, 2014)
Case definitions (Jun 25, 2014)
Interim guidance for healthcare professionals (Jul 29, 2014)
Guidance for travelers (May 21, 2014)
Infection prevention and control guidelines (Jul 11, 2014)
Information and guidance for clinicians (Jun 18, 2013)
Guidance on air medical transport for MERS patients (Jul 3, 2014)

Interim guidance for airline crew
(Mar 10, 2014)
Guidelines for evaluation of MERS-CoV (Jun 7, 2013)                                                                                   Interim guidelines for collection, processing and transport of clinical specimens (Jun 7, 2013)          Interim guidance for preventing MERS-CoV from spreading in homes and communities (Jul 11, 2014)
Interim home care and isolation guidance for MERS-CoV (Jul 11, 2014)
Advanced molecular detection (Aug 25, 2014)
MERS-CoV Images                                                   

European Centre for Disease Prevention and Control (ECDC)

MERS-CoV page
Updated rapid risk assessment (Apr 25, 2014) 
Epidemiologic update
(May 16, 2014)

Public Health England (PHE)

MERS-CoV page
Key facts  (Oct 4, 2013)
Risk assessment (May 2, 2014)
Treatment of MERS-CoV: Decision support tool (Jul 14, 2014)
Infection control advice (Jun 28, 2013)
Primary care algorithm for MERS & avian flu (May 28, 2014)
Algorithm for management of possible cases (Jul 14, 2014)
Algorithm for management of close contacts (May 16, 2014)
Epidemiologic protocols (Nov 11, 2013)

Food and Drug Administration (FDA)

RT-PCR Assay fact sheet for health care professionals (Jun 12, 2014)
RT-PCR assay fact sheet for patients (Jun 12, 2014) 
Emergency use authorization (Jun 10, 2014)

World Organization for Animal Health (OIE)

Questions and answers  (Aug 2014)

Public Health Agency of Canada (PHAC)

Risk assessment (Oct 8, 2014)
Public health notice (Oct 1, 2014)
Travel health notice (Jul 24, 2014)
Infection prevention and control guidance (Oct 4, 2013)
Interim case definition (Sep 23, 2013)
Coronavirus in animals (May 28, 2013)
Case report form (Apr 22, 2013) 

Saudi Arabia Ministry of Health (MOH)

MERS-CoV Page 
Infection prevention and control precautions (May 15, 2013)
Frequently asked questions
Procedures for suspected or confirmed cases 
Media Statements  

Twitter 

CIDRAP (@CIDRAP)
Helen Branswell (@HelenBranswell)
Michael Coston (@Fla_Medic)
ECDC (@ECDC_EU)
Martin Enserink (@martinenserink)
FluTrackers (@FluTrackers)
Jason Gale (@jwgale)
Gregory Hartl (@HaertlG)
HealthMap.org (@healthmap)
Crawford Kilian (@crof)
Ian M Mackay, PhD (@MackayIM)
Maia Majumder, MPH (@maiamajumder)
NPR Global Health (@nprGlobalHealth)
Lisa Schnirring (@lisaschnirring)
Marc Sprenger (@ECDC_MSprenger)
World Health Organization (@WHO)

Recent Literature

Adney DR, Letko M, Ragan IK, et al. Bactrian camels shed large quantities of Middle East respiratory syndrome coronavirus (MERS-CoV) after experimental infection. Emerg Microbes Infect 2019 (published online May 23)

Alanazi KH, Abedi GR, Midgley CM, et al. Diabetes mellitus, hypertension, and death among 32 patients with MERS-CoV infection, Saudi Arabia. (Research letter) Emerg Infect Dis 2019 (published online Dec 10)

AlRuthia Y, Somily AM, Alkhamali AS, et al. Estimation of direct medical costs of Middle East respiratory syndrome coronavirus infection: a single-center retrospective chart review study. Infect Drug Resist 2019 Nov 7;12:3463-73

Arabi Y, Shalhoub S, Mandourah Y, et al. Ribavirin and interferon therapy for critically ill patients with the Middle East respiratory syndrome: a multicenter observational study. Clin Infect Dis 2019 (published online Jun 25)

Dighe A, Jombart T, Van Kerkhove MD, et al. A systematic review of MERS-CoV seroprevalence and RNA prevalence in dromedary camels: implications for animal vaccination. Epidemics 2019 (published online Jun 5)

Donnelly CA, Malik MR, Elkholy A, et al. Worldwide reduction in MERS cases and deaths since 2016. (Research letter) Emerg Infect Dis 2019 (published online Jul 8)

Farag E, Sikkema RS, Mohamedani AA, et al. MERS-CoV in camels but not camel handlers, Sudan, 2015 and 2017. Emerg Infect Dis 2019 (published online Nov 6)

Farooq HZ, Davies E, Ahmad S, et al. Middle East respiratory syndrome coronoavirus (MERS-CoV) — surveillance and testing in north England from 2012 to 2019. Int J Infect Dis 2020 (published online Jan 28)

Folegatti PM, Bittaye M, Flaxman A, et al. Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non-randomised, uncontrolled, phase 1 trial. Lancet Infect Dis 2020 (published online Apr 20)

Grant R, Malik MR, Elkholy A, et al. A review of asymptomatic and sub-clinical Middle East respiratory syndrome coronavirus infections. Epidemiol Rev 2019 (published online Nov 29)

Habib AMG, Ali MAE, Zouaoui BR, et al. Clinical outcomes among hospital patients with Middle East respiratory syndrome coronavirus (MERS-CoV) infection. BMC Infect Dis 2019 Oct 22;19:870

Hakawi A, Rose EB, Biggs HM, et al. Middle East respiratory syndrome coronavirus, Saudi Arabia, 2017-2018. (Research letter) Emerg Infect Dis 2019 (published online Aug 20)

Harvey R, Mattiuzzo G, Hassall M, et al. Comparison of serologic assays for Middle East respiratory syndrome coronavirus. Emerg Infect Dis 2019 (published online Aug 20)

Hemida MG, Waheed M, Ali AM, et al. Detection of the Middle East respiratory syndrome coronavirus in dromedary camel’s seminal plasma in Saudi Arabia 2015‐2017. Transbound Emerg Dis 2020 (published online May 6)

Kain T, Lindsay PJ, Adhikari NKJ, et al. Pharmacologic treatments and supportive care for Middle East respiratory syndrome. Emerg Infect Dis 2020 Jun;26(6)

Koch T, Dahlke C, Fathi A, et al. Safety and immunogenicity of a modified vaccinia virus Ankara vector vaccine candidate for Middle East respiratory syndrome: an open-label, phase 1 trial. Lancet Infect Dis 2020 (published online Apr 20)

Modjarrad K, Roberts CC, Mills KT, et al. Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial. Lancet Infect Dis 2019 (published online Jul 24)

Momattin H, Al-Ali AY, Tawfiq JA. A systematic review of therapeutic agents for the treatment of Middle East respiratory syndrome coronavirus (MERS-CoV). Travel Med Infect Dis (published online Jun 25)

Okba NMA, Raj VS, Widjaja I, et al. Sensitive and specific detection of low-level antibody responses to mild Middle East respiratory syndrome coronavirus infections. Emerg Infect Dis 2019 (published online Aug 19)

Salamatbakhsh M, Mobaraki K, Sadeghimohammadi S, et al. The global burden of premature mortality due to the Middle East respiratory syndrome (MERS) using standard expected years of life lost, 2012 to 2019. BMC Public Health 2019 Nov 14;19:1523

Van Doremalen N, Haddock E, Feldmann F, et al. A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques. Sci Adv 2020 (published online May 1)

Van Kerkhove MD, Alaswad S, Assiri A, et al. Transmissibility of MERS-CoV infection in closed setting, Riyadh, Saudi Arabia, 2015. Emerg Infect Dis 2019 (published online Aug 20)

Zheng J, Hassan S, Alagaili AN, et al. Middle East respiratory syndrome coronavirus seropositivity in camel handlers and their families, Pakistan. Emerg Infect Dis 2019 (published online Nov 6)

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