"I don't think we should wait for a seasonal approach to this [COVID-19 vaccination] because this is not a seasonal disease yet."

"We have to address the challenges with health care. We have to realize that getting prepared for the next one [pandemic] means actually stockpiling vaccines and the kinds of things like N95 respirators. Well, we now have an administration that's tried to make that happen, but Congress has turned it down flat. If we had a pandemic emerge tomorrow, we would be in worse shape for that pandemic response than we were in 2019 and 2020."

“I do think that given the data that we’ve seen on waning immunity over time, that if somebody wanted to be vaccinated [against COVID-19] every six months and if they were in a high-risk group by age or underlying health condition, then I think that should be permitted. I don’t believe for a moment that it will be a widespread practice.”

"There are many cold criminal cases that never get solved, despite intense efforts to do so because they don't have sufficient evidence as to what happened. I think you have a very similar situation here [origin of SARS-CoV-2]. We're never really going to know." 

"When an agency [US Department of Energy] comes out and says they're leaning this way [China SARS-CoV-2 lab leak] but with 'low confidence?' I mean, how do you interpret that? The question is: 'Why did you even put it out there?'"

"It's not unusual to see an influenza B resurgence after the big A peak, but we've really seen no evidence of that so far."

“It’s one of those issues where every sudden event that results in death or some kind of cardiac issue, people are now saying it’s due to the COVID-19 vaccine, without any information. And that story gets repeated enough times, and people start to believe it. Ask me what I would recommend to the people who matter most to me. Get the vaccine."

“My focus is on people who are 65 and older and those who are immune-compromised. That’s who I think really should get” a COVID-19 booster.

“That may be one of the cruelest things of all. If we basically prevent [older people] from getting infected [with COVID-19] by isolating them to where it’s loneliness that does them in.”

“Trying to predict what H5N1 [avian flu] will do in the human population absolutely requires a great deal of scientific humility. I will never, ever, take H5N1 for granted. I just don’t know what it’s going to do.”

"We will still have access to free vaccines and drugs," after the US COVID-19 pandemic emergency ends in May. "Testing may be a challenge in the sense that it's not currently covered, and we've got to look at how we're going to cover that."

"People all assumed we would see major [COVID-19] transmission [this winter]. Well, every time we think we have some reason to believe we know what it's going to do, it doesn't do that,"

“I’m getting more [COVID-19] intelligence from China right now, by far, from news reporters on the ground, or from private sector companies [than from the government]."

“I don’t think we have a real sense of what variants to be concerned about and which not to be."

"People are trying to figure out 'Well, how do we adjust to this virus [SARS-CoV-2]?' We could make this decision today to go with a once-a-year vaccine. But what happens if a new variant emerges in July and suddenly has major changes for the world?"

 The poultry industry likely cannot “sustain itself in countries like the U.S. if we continue to see annual surges" of H5N1 avian flu.

“We are watching this antibiotic era turn into a post-antibiotic era,” regarding a newly identified strain of antibiotic-resistant gonorrhea in the United States. "That is a scary proposition.”

“The bivalent vaccine is working as well as we could have expected. The challenge we have is, what does that mean going forward?”

“Every day, I hear from people who are misinformed by their physicians or call-in nurse lines. Generally, they’re being told you can’t get Paxlovid until you’re seriously ill—which is just the opposite of what’s recommended. Why are we not doing more to educate the medical community?”

“None of us yet really understand how to interpret the scientific information that continues to come in on variants and subvariants and try to translate that into meaningful public health policy—or for that matter, how to even talk about it. I think we’re in a place right now where we’re trying to understand: How do we talk about this [in a way] that’s meaningful to people and that has public health consequence?”