The designation means that the NgG vaccine, which is in a phase 2 trial, will receive expedited review by FDA officials.
Analysis of Neisseria gonorrhoeae isolates from 3 African countries finds high resistance to ciprofloxacin and emerging resistance determinants for azithromycin.
Gonorrhea infections rose 50% in 2022 compared with 2021, and infectious syphilis diagnoses increased 15%.
Gonorrhea and chlamydia cases increased by 4% in 2021, while syphilis cases rose by 32%.
Trial results were so compelling that researchers stopped the trial early to give all participants post-exposure prophylaxis with doxycycline.
Officials have received a growing number of reports of XDR Shigella, which is highly transmissible and resistant to commonly recommended antibiotics, in adults.
State health officials say the strain, which had reduced susceptibility to the last remaining recommended antibiotic treatment, is a serious public health concern.
Data suggest 4CMenB protection against gonorrhea and support the feasibility of a gonococcal vaccine.
CARB-X announced today that it is awarding Australian diagnostics company SpeeDx up to $1.8 million to develop a rapid molecular diagnostic test for chlamydia and gonorrhea infections.
A pilot trial conducted at two emergency departments (EDs) found that audit and feedback with peer-to-peer comparisons reduced antibiotic prescribing for viral acute respiratory infections (ARIs) but not overall antibiotic use, researchers reported today in Open Forum Infectious Diseases.
