The 10 new flu-related deaths in children bring the season's total to 226, the most since 2009-10.
The loss of activity is equivalent to 15% of the US population becoming completely immobile for 1 day.
Adult COVID-19 patients also infected with the flu are 4 times more likely to need mechanical ventilation and 2.4 times more likely to die.
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Though H10 viruses have infected humans before, the woman's illness marks the first known case involving H10N5.
In a preliminary flu season severity assessment, the CDC said the season has been moderate.
Activity is rising in Europe and Central Asia, with declines in other regions, including parts of East Asia and the Arabian Peninsula.
Signs are encouraging, though activity sometimes rises again after the holiday period.
The greatest reductions occurred when the breaks coincided with elevated local flu activity.
Some downward trends might reflect changes in holiday-related health seeking behaviors.
Influenza A currently makes up the majority of global detections, with H3N2 most common among subtyped samples.
Though COVID wastewater and test positivity are higher than last year at this time, medical encounters are trending lower.
Relative to flu patients, those infected with Omicron BA.5 had higher rates of vasopressor use, renal replacement therapy, and in-hospital death.
Flu and COVID indicators continued upward trends, with different regions reporting the most intensive activity.
