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A German research team that analyzed and compared H7N9 influenza virus from a diseased human and H7 viruses from birds found that the human strain replicated as well as seasonal flu in lab culture designed to mimic human lung tissue, but the avian H7 strain grew poorly. They reported their findings yesterday in the latest edition of mBio.
In a randomized controlled trial in France, a statin drug failed to improve survival rates in patients with ventilator-associated pneumonia (VAP), according to a report published online today by the Journal of the American Medical Association (JAMA).
Multistate outbreak affecting hundreds highlights public health consequences of fed shutdown.
At a malaria conference in South Africa today, researchers reported more promising findings for a vaccine that is furthest along in development, and GlaxoSmithKline (GSK) officials said they now intend to submit a regulatory application for it to the European Medicines Agency (EMA) in 2014, according to a company press release.
Wearing gowns and gloves in all ICU rooms didn't lower the combined levels of two key drug-resistant threats significantly.
Indonesia's Ministry of Health has confirmed the country's second H5N1 case this year, in a 28-year-old man from Bekasi.
The man died from the disease, according to a machine-translated health ministry statement today on FluTrackers, the Web-based infectious disease message board. The health ministry statement is dated Oct 3.
The cases, apparently previously reported by Saudi Arabia, raise the global count to 136, with 58 deaths.
A vaccine targeting two common norovirus strains reduced vomiting and diarrhea and prevented severe illness in a small clinical challenge study, researchers reported today at the IDWeek conference in San Francisco.
The rate of needless antibiotic prescribing for the two conditions has stayed level for years.
Neither the seasonal trivalent (three-strain) influenza vaccine (TIV) nor a monovalent H3N2 vaccine substantially reduced shedding of variant H3N2 (H3N2v) virus in ferrets, but previous infection with a seasonal H3N2 virus did, according to a study yesterday in the Journal of Virology.
A two-drug combination may be effective against Middle East respiratory syndrome coronavirus (MERS-CoV), according to the results of a cell-culture study published today in the Journal of Infection.
New federal contracts establish a "fill and finish" network for flu vaccine to boost capacity by 20%.
Researchers who used a sophisticated modeling approach incorporating H7N9 case data from China found hints that the virus has low transmission potential and that the pace of infection slowed in April after officials closed live-bird markets.
The World Health Organization (WHO) and other health groups yesterday launched what they billed as the first global action plan to stop tuberculosis (TB) in children, saying it could save as many as 74,000 lives each year.
Response to seasonal flu, H7N9, MERS, and other threats could be markedly diminished.
Saudi Arabia has reported three more Middle East Respiratory syndrome coronavirus (MERS-CoV) cases, according to a machine-translated Saudi government statement posted on disease-tracking Web sites.
Saudi Arabia reports three more MERS cases, and a serologic study finds no evidence of exposure.
Clusters of children who had nonmedical exemptions (NMEs) from vaccines appears to be one of several factors that played a role in California's 2010 pertussis (whooping cough) epidemic, researchers reported today in Pediatrics.
Cases in recent months show steep declines in the percent of severe and fatal cases.
The World Health Organization (WHO) yesterday recommended a specific H7N9 influenza strain for vaccine development, saying it "elicits antibodies that react well with all viruses tested."
In a statement, the WHO said it has selected an A/Anhui/1/2013-like virus for the development of H7N9 vaccines for pandemic preparedness. It notes that A/Shanghai/2/2013 is an A/Anhui/1/2013-like virus.
