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Patients in several high-income countries still have limited access to most of the new antibacterials approved since 2010, and as a result sales revenue for these drugs has been insufficient—findings that highlight the poor commercial prospects for new antibiotics, researchers reported yesterday in Clinical Infectious Diseases.
Today a consensus statement by several leading public health organizations and a commentary in the Annals of Internal Medicine voiced support for mandating COVID-19 vaccinations in US healthcare workers (HCWs).
WHO head Tedros urges Moderna and Pfizer to go all out on channeling vaccine supply to COVAX.
The FDA and the CDC said so far there are not enough data to recommend a booster.
Two doses of different vaccines were 80% to 89% effective in at-risk patients 65 years and older.
People who received the flu vaccine prior to having COVID-19 had less risk of sepsis, stroke, deep vein thrombosis (DVT), and disease requiring emergency or intensive care, according to a study presented at the European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) this year.
A study of hospital patients in Israel found a link between multidrug-resistant gut bacteria and exposure to commonly used non-antimicrobial drugs (NAMDs), researchers reported last week at the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID).
Sixteen African nations report resurgences, and cases have more than doubled in some European countries.
The CDC says vaccines are "one of the most critical strategies to help schools safely resume full operations."
The vaccine had good efficacy against infection and severe disease, but lower than with mRNA vaccines.
"Americans who have been fully vaccinated do not need a booster shot at this time," the agencies say.
Our weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scans
The London School of Hygiene and Tropical Medicine (LSHTM) announced today that it is partnering with Johnson & Johnson (J&J) to launch a center focused on research into antimicrobial resistance and tuberculosis (TB).
In Orange County, California, COVID-19 vaccination in healthcare personnel (HCP) was connected with a 94% reduction in HCP cases 3 weeks after second doses of mRNA-based vaccines were administered, according to a JAMA Network Open research letter yesterday.
"We are now starting to see new and concerning trends in cases," CDC Director Rochelle Walensky says.
A report notes significant differences in the use of various antibiotic classes between the 2 databases studied.
Also, global deaths pass 4 million, led by the United States, India, and Brazil.
Recommendations include bolstering worker well-being, reassessing priorities, and admitting when data are lacking.
A urine culture stewardship initiative at a teaching hospital in Michigan reduced overuse of urine cultures and was associated with a significant decline in catheter-associated urinary tract infections (CAUTIs), researchers reported today in Infection Control & Hospital Epidemiology.
The US COVID-19 vaccination program may have saved almost 280,000 lives and prevented 1.25 million hospitalizations, according to the results of a modeling study published yesterday by the Commonwealth Fund.
