The European health agency says decisions on doxycycline post-exposure prophylaxis use should be made at the individual level, following clinical judgement and national guidelines.
Data on more than 1.4 millions incarcerated individuals in 43 countries shows STI rates are particularly high in adolescents and women.
The report is in response to a continent-wide surge in STIs since 2014.
Reported cases of chlamydia, gonorrhea, and syphilis declined for the third straight year in 2024, but cases of newborn syphilis were up by 2%.
The findings indicate that expanding gonorrhea and chlamydia screening in emergency departments may be warranted, the authors say.
A genomic analysis finds the percentage of US gonorrhea isolates carrying tetracycline resistance genes rose from 10% in 2020 to more than 30% in 2024.
Doxycycline post-exposure prophylaxis isn't formally available in the Netherlands, but 23% of respondents to an online survey said they've used it.
A study at a sexual health clinic finds that significant declines in chlamydia and syphilis were sustained nearly 2 years after doxy-PEP was introduced.
A study of 40 female sex workers reveals that a single daily dose of doxycycline is associated with significantly reduced STIs, primarily syphilis.
The at-home test can detect chlamydia, gonorrhea, and trichomoniasis and deliver results within 30 minutes.
