The delay, narrowed approval, and extra study steps raise concerns about the status of and potential added requirements for other COVID vaccines.
Plaque growth can lead to a higher risk of heart attack, stroke, and other life-threatening cardiovascular events for as long as 1 year.
Post-exertional malaise, or exercise intolerance, was seen in 36% of those with long COVID.
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Current vaccine strains show high neutralization against the latest variants, but the LP.8.1 antigen may provide similar or moderately higher cross-reactive antibody response.
Although the risk was greater with moderate-to-severe infections, even mild cases were linked to more than double the risk.
Sewer sampling, the authors say, could be expanded to track other infectious diseases such as H5N1 avian flu or mpox or to detect unexpected pathogens.
The risk of long COVID was two to three times higher after the initial infection (14.8%) than after first (5.8%) or second (5.3%) reinfections.
Overall, the hazard ratio for in-hospital mortality at 28 days was 0.73.
While incidence of community-associated and healthcare-associated community-onset MRSA bacteremia declined during the pandemic, hospital-onset cases rose substantially.
The 10 new flu-related deaths in children bring the season's total to 226, the most since 2009-10.
Health disparities are shortening lives by decades in high- and low-income countries alike, the World Health Organization says.
The combined vaccine elicited higher immune response against SARS-CoV-2.
Overweight and obesity were significantly associated with memory issues and persistent headache, among other conditions.
