Current vaccine strains show high neutralization against the latest variants, but the LP.8.1 antigen may provide similar or moderately higher cross-reactive antibody response.
Plaque growth can lead to a higher risk of heart attack, stroke, and other life-threatening cardiovascular events for as long as 1 year.
Post-exertional malaise, or exercise intolerance, was seen in 36% of those with long COVID.
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The incidence dropped by one-fifth for both mRNA vaccines when dose spacing was longer.
The Journal of Infectious Diseases has published studies demonstrating lower COVID-19 incidence—but a higher risk of severe disease—in people with Down syndrome (DS), and a lower COVID vaccine immune response.
An additional 600,000 lives might have been saved if global vaccination goals had been met.
A study yesterday in JAMA Internal Medicine shows that a fourth Pfizer COVID-19 vaccine dose provided 64% to 67% protection against hospitalization and 72% protection against death in nursing home residents, but only 34% protection against infection during an Omicron-dominated period.
The absolute risk appears to be only slightly higher than in uninfected peers.
Maternal COVID vaccination during pregnancy provides 52% protection against COVID-19 hospitalization in infants but only 38% protection against Omicron hospitalization, according to a study yesterday in the New England Journal of Medicine.
Protection against an intensive care unit (ICU) stay, however, was 70%.
Only 0.74% of patients visited an emergency department and only 0.11% a hospital.
The vaccine produces a strong immune response against the BA.4 and BA.5 Omicron subvariants.
Women had a broader symptom profile than men, who were more likely to have diabetes or kidney problems.
The United Kingdom today expanded monkeypox vaccination to include men who have sex with men who are in high-risk groups, instead of just those who are known contacts and those at occupational risk.
